Page last updated: 2024-09-28

Hereditary Optic Atrophy

Hereditary conditions that feature progressive visual loss in association with optic atrophy. Relatively common forms include autosomal dominant optic atrophy (OPTIC ATROPHY, AUTOSOMAL DOMINANT) and Leber hereditary optic atrophy (OPTIC ATROPHY, HEREDITARY, LEBER).

Synonyms(3)

Synonym
Optic Atrophy, Hereditary
Hereditary Optic Atrophy
Optic Atrophies, Hereditary

Research

Studies (101)

TimeframeStudies, This Condition (%)All Conditions %
pre-199010 (9.90)23.3326
1990's67 (66.34)12.5806
2000's13 (12.87)18.1394
2010's9 (8.91)28.8240
2020's2 (1.98)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low40
carbon monoxide0low10
formic acid0low10
lactic acid0medium51
glycine0low10
hydrogen0low10
pyruvic acid0medium21
taurine0low10
thymine0low10
meglutol0low10
erythrosine0low20
hydroxychloroquine0low10
lidocaine0low10
idebenone0low40
isoflurane0low10
2-propanol0low10
oxazepam0low10
pentoxifylline0low10
alanine0low30
serine0low20
aspartic acid0low10
glutamine0low20
lysine0low10
cyanides0low20
adenosine diphosphate0low40
galactose0low20
tyrosine0low10
adenosine monophosphate0low10
leucine0low10
phenylalanine0low10
histidine0low50
threonine0low20
arginine0low60
methylprednisolone0low10
rotenone0low70
thiazoles0low10
3-methylglutaric acid0low10
ethambutol0low10
d-alpha tocopherol0low10
fluorescein0low20
europium0low10
cephalexin0low10
zidovudine0low10
vecuronium bromide0low10
propiconazole0low30
lopinavir0low10
4-hydroxy-25-desoxyneorollinicin0low20
proline0low10
tetraphenylphosphonium0low10
darunavir0low10
ritonavir0low10
tacrolimus0low10
riboflavin0low10
3-methylglutaconic acid0low40
ubiquinone q20low10
11-cis-retinal0low20
coenzyme q100low50
cysteine0low10
phosphorus0low30
myxothiazol0low10
phosphocreatine0low40
nad0low20
oligonucleotides0low30
ubiquinone0low120
cobicistat0low10
glycolipids0low10
interleukin-80low10
hydroxocobalamin0low10
ascorbic acid0low20
cyclosporine0low10
cyclic gmp0low60
guanosine triphosphate0low10
guanine0low50
guanosine0low10
folic acid0low10
eye0low60
phosphorus radioisotopes0low10

Protein Targets (743)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Retinaldehyde-binding protein 10011
Chain A, Retinaldehyde-binding protein 10011
hypoxia-inducible factor 1 alpha subunit6006
RAR-related orphan receptor gamma140014
GLI family zinc finger 3130013
AR protein210021
aldehyde dehydrogenase 1 family, member A18008
retinoic acid nuclear receptor alpha variant 1170017
retinoid X nuclear receptor alpha130013
estrogen nuclear receptor alpha250025
peroxisome proliferator-activated receptor delta9009
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
activating transcription factor 69009
v-jun sarcoma virus 17 oncogene homolog (avian)9009
Histone H2A.x4004
thyroid hormone receptor beta isoform a6006
heat shock protein beta-16006
nuclear factor erythroid 2-related factor 2 isoform 1140014
lamin isoform A-delta10140014
Voltage-dependent calcium channel gamma-2 subunit7007
Glutamate receptor 27007
glp-1 receptor, partial3003
TDP1 protein160016
geminin9009
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
nuclear receptor subfamily 1, group I, member 38008
cytochrome P450 family 3 subfamily A polypeptide 4120012
glucocorticoid receptor [Homo sapiens]150015
estrogen-related nuclear receptor alpha180018
pregnane X nuclear receptor120012
nuclear factor erythroid 2-related factor 2 isoform 24004
importin subunit beta-1 isoform 13003
snurportin-13003
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
Bile salt export pump011011
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0214
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 432002
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 57007
Ataxin-28008
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
regulator of G-protein signaling 45005
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70022
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
2-dehydropantoate 2-reductase0235
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0202
Mu-type opioid receptor0213
Delta-type opioid receptor0011
Kappa-type opioid receptor0213
Endoplasmin0112
P2Y purinoceptor 20022
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10011
P2Y purinoceptor 10022
P2Y purinoceptor 10022
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 14004
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110022
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120011
Sensor protein kinase WalK0101
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20011
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
euchromatic histone-lysine N-methyltransferase 2140014
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0203
Fructose-1,6-bisphosphatase 10101
Inosine-5'-monophosphate dehydrogenase0101
Cytochrome P450 2C9 0404
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0101
5'-nucleotidase0001
Choline O-acetyltransferase0101
Adenylate kinase 2, mitochondrial0102
GTP:AMP phosphotransferase AK3, mitochondrial0001
Adenosine receptor A10011
Adenylate kinase isoenzyme 1 0102
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 07415
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
ATP-dependent phosphofructokinase7007
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
Carbonic anhydrase 10108
Carbonic anhydrase 20108
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0003
Glutamate receptor ionotropic, NMDA 1 0519
Proton-coupled amino acid transporter 10607
Adenosine deaminase0001
Carbonic anhydrase 40003
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
thioredoxin reductase5005
phosphopantetheinyl transferase8008
NFKB1 protein, partial2002
GLS protein6006
thyroid stimulating hormone receptor4004
alpha-galactosidase3003
cytochrome P450 2C19 precursor4004
chromobox protein homolog 16006
flap endonuclease 14004
DNA polymerase iota isoform a (long)5005
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)7007
Cytochrome P450 3A40709
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase7007
thioredoxin glutathione reductase3003
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
IDH15005
thyroid hormone receptor beta isoform 2120012
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Polyphenol oxidase 20102
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0112
Spike glycoprotein7029
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
Chain A, Ferritin light chain8008
arylsulfatase A4004
Bloom syndrome protein isoform 16006
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0317
Glutamate receptor ionotropic, NMDA 2B0317
Glutamate receptor ionotropic, NMDA 2C0317
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0005
Glutamate receptor ionotropic, NMDA 2D0317
Glutamate receptor ionotropic, NMDA 3B0317
Glutamate receptor ionotropic, NMDA 3A0317
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Microtubule-associated protein tau7007
bromodomain adjacent to zinc finger domain 2B4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
vitamin D3 receptor isoform VDRA5005
mitogen-activated protein kinase 15005
Solute carrier family 22 member 60203
Interferon beta8008
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Solute carrier family 15 member 20102
Solute carrier family 22 member 80101
Cytochrome P450 1A20202
Cytochrome P450 2D60303
Cytochrome P450 2C190404
Broad substrate specificity ATP-binding cassette transporter ABCG20404
Protease 07513
peripheral myelin protein 227007
Carbonic anhydrase 40104
Carbonic anhydrase0104
Carbonic anhydrase 150104
Phosphodiesterase 0101
Multidrug resistance-associated protein 409011
Multidrug resistance-associated protein 50001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
USP1 protein, partial6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
Rap guanine nucleotide exchange factor 31001
Cellular tumor antigen p53140014
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, Pol Polyprotein0101
Chain A, Pol Polyprotein0101
Chain B, Pol Polyprotein0101
Chain A, Pol Polyprotein0101
Chain B, Pol Polyprotein0101
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, protease0101
Chain B, protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease (Retropepsin)0011
Chain B, Protease (Retropepsin)0011
Chain A, Protease (Retropepsin)0011
Chain B, Protease (Retropepsin)0011
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, HIV-1 Protease0101
Chain B, HIV-1 Protease0101
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, HIV-1 protease0011
Chain B, HIV-1 protease0011
Chain A, HIV-1 protease0011
Chain B, HIV-1 protease0011
Chain A, HIV-1 Protease0011
Chain B, HIV-1 Protease0011
Chain A, Protease0011
Chain B, Protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, HIV-1 protease0101
Chain B, HIV-1 protease0101
Chain A, HIV-1 protease0101
Chain B, HIV-1 protease0101
Chain A, HIV-1 protease0101
Chain B, HIV-1 protease0101
Chain A, Protease0011
Chain B, Protease0011
Chain A, Pol polyprotein0101
Chain B, Pol polyprotein0101
EWS/FLI fusion protein7007
G7007
cytochrome P450 2D68008
nuclear receptor subfamily 1, group I, member 24004
potassium voltage-gated channel subfamily H member 2 isoform d4004
HLA class I histocompatibility antigen, B alpha chain 7007
Gag-Pol polyprotein0303
ATP-dependent translocase ABCB10404
Replicase polyprotein 1ab0325
Replicase polyprotein 1ab0527
Gag-Pol polyprotein0213
Potassium voltage-gated channel subfamily E member 10101
Alpha-1B adrenergic receptor0303
Alpha-1D adrenergic receptor0303
Alpha-1A adrenergic receptor0303
Potassium voltage-gated channel subfamily KQT member 10101
Potassium voltage-gated channel subfamily H member 20404
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0202
Inositol hexakisphosphate kinase 17007
Gag-Pol polyprotein0101
Potassium voltage-gated channel subfamily D member 30101
cytochrome P450 2C9, partial7007
Chain A, Beta-lactamase5005
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
Genome polyprotein 0213
Luciferase6006
chaperonin-containing TCP-1 beta subunit homolog1001
SMAD family member 28008
ATAD5 protein, partial4004
Fumarate hydratase4004
SMAD family member 38008
hypothetical protein, conserved1001
farnesoid X nuclear receptor8008
polyprotein4004
aryl hydrocarbon receptor7007
thyroid stimulating hormone receptor5005
thyrotropin-releasing hormone receptor3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
eyes absent homolog 2 isoform a1001
DNA polymerase kappa isoform 17007
histone acetyltransferase KAT2A isoform 16006
relaxin receptor 1 isoform 12002
Flavin reductase (NADPH)0011
large T antigen0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0001
Pantothenate synthetase0101
estrogen receptor 2 (ER beta)9009
progesterone receptor9009
peroxisome proliferator activated receptor gamma9009
Chain A, Dihydrofolate reductase0011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, 2-oxoglutarate Oxygenase3003
acid sphingomyelinase1001
glucocerebrosidase2002
lysosomal alpha-glucosidase preproprotein1001
DNA polymerase beta2002
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10101
Alpha-synuclein1001
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Chain A, Glutamine Binding Protein0011
15-lipoxygenase, partial2002
peripheral myelin protein 22 isoform 13003
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Neutral amino acid transporter A0303
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0303
Amino acid transporter0303
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10506
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0203
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Adenosylhomocysteinase0102
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
67.9K protein2002
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
Chain A, HISTIDINE-BINDING PROTEIN0011
cytochrome P450 3A4 isoform 14004
Gamma-aminobutyric acid receptor subunit pi4004
Carbonic anhydrase 120003
Plasma kallikrein0003
Carbonic anhydrase 30003
Histidine-binding periplasmic protein0011
Gamma-aminobutyric acid receptor subunit beta-14004
Gamma-aminobutyric acid receptor subunit delta4004
Gamma-aminobutyric acid receptor subunit gamma-24004
Gamma-aminobutyric acid receptor subunit alpha-54004
Gamma-aminobutyric acid receptor subunit alpha-34004
Carbonic anhydrase 60003
Gamma-aminobutyric acid receptor subunit gamma-14004
Gamma-aminobutyric acid receptor subunit alpha-24004
Adenosine receptor A10003
Gamma-aminobutyric acid receptor subunit alpha-44004
Gamma-aminobutyric acid receptor subunit gamma-34004
Gamma-aminobutyric acid receptor subunit alpha-64004
Adenosine receptor A2a0003
Carbonic anhydrase 5A, mitochondrial0003
Carbonic anhydrase 70003
Carbonic anhydrase0003
Gamma-aminobutyric acid receptor subunit alpha-14004
Gamma-aminobutyric acid receptor subunit beta-34004
Gamma-aminobutyric acid receptor subunit beta-24004
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 90003
Carbonic anhydrase 0003
Carbonic anhydrase0003
Carbonic anhydrase0003
Carbonic anhydrase 0003
Carbonic anhydrase 130002
GABA theta subunit4004
Carbonic anhydrase 130002
Gamma-aminobutyric acid receptor subunit epsilon4004
Carbonic anhydrase 140003
Carbonic anhydrase 5B, mitochondrial0003
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0022
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0101
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Muscarinic acetylcholine receptor M10101
Alpha-2C adrenergic receptor0101
Muscarinic acetylcholine receptor M30101
Alpha-1D adrenergic receptor0202
Sigma intracellular receptor 20101
Cyclic GMP-AMP synthase0101
Sigma non-opioid intracellular receptor 10101
Angiotensin-converting enzyme 2 0022
Toll-like receptor 90101
Toll-like receptor 70101
huntingtin isoform 21001
nuclear receptor ROR-gamma isoform 16006
Polyunsaturated fatty acid 5-lipoxygenase0101
NAD-dependent protein deacetylase sirtuin-20101
NAD-dependent protein deacetylase 0101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
cellular tumor antigen p53 isoform a1001
Integrin beta-31001
Integrin alpha-IIb1001
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Potassium channel subfamily K member 30101
ATP-binding cassette sub-family C member 30909
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Canalicular multispecific organic anion transporter 10909
Multidrug and toxin extrusion protein 10303
Sodium channel protein type 3 subunit alpha0101
Chain A, protease0101
Chain B, protease0101
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, protease0011
Chain B, protease0011
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, Protease0101
Chain B, Protease0101
Chain A, PROTEASE RETROPEPSIN0101
Chain B, PROTEASE RETROPEPSIN0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Chain A, Protease Retropepsin0101
Chain B, Protease Retropepsin0101
Smad31001
Albumin0026
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
Gag-Pol polyprotein0202
CAAX prenyl protease 1 homolog0101
Plasmepsin V 0202
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Glutathione reductase, mitochondrial0202
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
PPM1D protein2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
nonstructural protein 13003
muscleblind-like protein 1 isoform 11001
Nuclear receptor subfamily 1 group I member 20033
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Androgen receptor0202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nuclear receptor subfamily 1 group I member 20011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Translocator protein0101
endonuclease IV1001
dopamine D1 receptor1001
vasopressin V1b receptor1001
survival motor neuron protein isoform d2002
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tumor necrosis factor0101
Cholinesterase0101
Acetylcholinesterase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A2b0101
Disintegrin and metalloproteinase domain-containing protein 171001
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chitotriosidase-10213
Endochitinase B10213
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
E3 ubiquitin-protein ligase XIAP0101
SLC16A10 protein0002
Large neutral amino acids transporter small subunit 1 0101
Monocarboxylate transporter 100002
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
pregnane X receptor2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
heat shock protein HSP 90-alpha isoform 20001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histamine H2 receptor2002
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Solute carrier family 22 member 200101
Prolyl 4-hydroxylase0101
Solute carrier family 22 member 60101
Solute carrier organic anion transporter family member 2A10101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain A, Breast cancer type 1 susceptibility protein1001
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
tumor necrosis factor1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
caspase-1 isoform alpha precursor1001
Riboflavin-binding protein0112
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Caspase-71001
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, Cruzipain3003
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
neuropeptide S receptor isoform A2002
Solute carrier family 22 member 20202
Solute carrier family 22 member 1 0101
Solute carrier family 22 member 30101
Solute carrier organic anion transporter family member 2B1 0202
Gag-Pol polyprotein0101
ATP-dependent translocase ABCB10101
Cytochrome P450 3A50202
ATP-dependent translocase ABCB10101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Thromboxane-A synthase 0101
Vasopressin V1a receptor0202
Thromboxane-A synthase0001
Sodium/bile acid cotransporter0101
Multidrug and toxin extrusion protein 20202
Solute carrier organic anion transporter family member 1B30202
Solute carrier organic anion transporter family member 1B10303
NPC intracellular cholesterol transporter 1 precursor1001
cytochrome P450 2C9 precursor1001
atrial natriuretic peptide receptor 1 precursor1001
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 12002
M-phase phosphoprotein 81001
Pancreatic triacylglycerol lipase0101
NADH-ubiquinone oxidoreductase chain 10101
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial0101
Dihydroorotate dehydrogenase (fumarate)0101
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Acyl carrier protein, mitochondrial0101
Dihydroorotate dehydrogenase 0101
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Cholinesterase0101
UDP-glucuronosyltransferase 2B70002
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
GALC protein1001
Sodium- and chloride-dependent taurine transporter0101
Chain A, Multidrug-efflux Transporter 1 Regulator Bmrr0011
Thymidine phosphorylase0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
Caspase-71001
caspase-31001
pyruvate kinase PKM isoform a1001
serine/threonine-protein kinase PLK11001
tyrosine-protein kinase Yes1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Ectonucleoside triphosphate diphosphohydrolase 10001
Thymidine kinase, cytosolic0203
Protein kinase C beta type0101
DNA polymerase beta0101
Thymidine kinase, cytosolic 0001
Thymidylate kinase0101
Protein kinase C epsilon type0101
Thymidine kinase 0102
Solute carrier family 22 member 60001
Solute carrier family 22 member 70001
Reverse transcriptase/RNaseH 0126
Solute carrier family 22 member 80001
Solute carrier family 22 member 110001
Thymidine kinase0102
Solute carrier family 22 member 70001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]