Page last updated: 2024-09-27

Hepatic Infarct

Formation of infarct resulting from obstruction of HEPATIC ARTERY and/or PORTAL VEIN most often after LIVER TRANSPLANTATION or hepatobiliary surgery.

Synonyms(4)

Synonym
Liver Infarct
Liver Infarction
Hepatic Infarct
Hepatic Infarction

Research Excerpts

Overview

ExcerptReference
"Liver infarction is usually managed by conservative therapy; interventional procedures such as percutaneous imaging-guided drainage or surgical evacuation should be reserved in cases where septic complications occur, with development of a hepatic abscess from the necrotic area."( Carlei, F; De Donato, MC; Di Cesare, E; Di Sibio, A; Ficorella, C; Giuliani, A; Latessa, M; Monti, R; Parisi, A; Romano, L; Schietroma, M; Varrassi, M; Venditti, O, 2020)

Treatment

ExcerptReference
"We report a case of segmental hepatic infarction following the adjuvant chemotherapy with Oxaliplatin and Capecitabine in a patient who had undergone total gastrectomy and distal esophagectomy for gastric cancer."( Carlei, F; De Donato, MC; Di Cesare, E; Di Sibio, A; Ficorella, C; Giuliani, A; Latessa, M; Monti, R; Parisi, A; Romano, L; Schietroma, M; Varrassi, M; Venditti, O, 2020)

Research

Studies (8)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's2 (25.00)28.8240
2020's6 (75.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
glycine0low10
thyroxine0low10
capecitabine0low10
tacrolimus0low10
mycophenolic acid0low10
stilbenes0low10
sb 2250020low10
pterostilbene0low10
technetium tc 99m mebrofenin0low10

Protein Targets (182)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma4004
TDP1 protein5005
estrogen nuclear receptor alpha5005
Liver carboxylesterase 10001
AR protein4004
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 1 0213
Sodium- and chloride-dependent glycine transporter 10101
Glutamate receptor ionotropic, NMDA 2A 0213
Glutamate receptor ionotropic, NMDA 2B0213
Glutamate receptor ionotropic, NMDA 2C0213
Large neutral amino acids transporter small subunit 10101
Glutamate receptor ionotropic, NMDA 2D0213
Proton-coupled amino acid transporter 10101
Glutamate receptor ionotropic, NMDA 3B0213
Serine racemase0101
Olfactory receptor 51E20011
Glutamate receptor ionotropic, NMDA 3A0213
Sodium- and chloride-dependent glycine transporter 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase2002
acetylcholinesterase1001
glp-1 receptor, partial2002
SMAD family member 21001
SMAD family member 31001
aldehyde dehydrogenase 1 family, member A11001
estrogen receptor 2 (ER beta)1001
nuclear receptor subfamily 1, group I, member 33003
progesterone receptor1001
glucocorticoid receptor [Homo sapiens]2002
retinoid X nuclear receptor alpha1001
estrogen-related nuclear receptor alpha3003
farnesoid X nuclear receptor1001
67.9K protein1001
peroxisome proliferator-activated receptor delta2002
peroxisome proliferator activated receptor gamma3003
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
euchromatic histone-lysine N-methyltransferase 22002
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
activating transcription factor 61001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
Histone H2A.x1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
nuclear factor erythroid 2-related factor 2 isoform 21001
thyroid hormone receptor beta isoform 23003
nuclear factor erythroid 2-related factor 2 isoform 13003
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
geminin3003
peripheral myelin protein 222002
survival motor neuron protein isoform d1001
cytochrome P450 3A4 isoform 11001
lethal factor (plasmid)1001
lamin isoform A-delta102002
Gamma-aminobutyric acid receptor subunit pi1001
UDP-glucuronosyltransferase 1A90001
Voltage-dependent calcium channel gamma-2 subunit2002
Cellular tumor antigen p533003
Inosine-5'-monophosphate dehydrogenase 20202
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Glutamate receptor 10101
Glutamate receptor 22103
Glutamate receptor 30101
Glutamate receptor 40101
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0102
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0033
Alpha-synuclein1001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
TAR DNA-binding protein 432002
Inosine-5'-monophosphate dehydrogenase0102
GABA theta subunit1001
ATPase family AAA domain-containing protein 52002
Ataxin-22002
Gamma-aminobutyric acid receptor subunit epsilon1001
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Luciferase2002
BRCA11001
phosphopantetheinyl transferase1001
Microtubule-associated protein tau1001
lysosomal alpha-glucosidase preproprotein1001
NPC intracellular cholesterol transporter 1 precursor1001
mitogen-activated protein kinase 11001
ras-related protein Rab-9A1001
FAD-linked sulfhydryl oxidase ALR0001
nuclear receptor ROR-gamma isoform 12002
Tyrosine-protein kinase ABL10102
Cytochrome P450 1A10101
ATP-dependent translocase ABCB10102
Neuronal acetylcholine receptor subunit alpha-40101
Polyunsaturated fatty acid 5-lipoxygenase0101
Breakpoint cluster region protein0102
Neuronal acetylcholine receptor subunit beta-20101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
5-hydroxytryptamine receptor 1A0001
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0001
Cytochrome P450 1B10101
Transient receptor potential cation channel subfamily A member 10112
Transient receptor potential cation channel subfamily V member 10101
NACHT, LRR and PYD domains-containing protein 3 0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
C-X-C chemokine receptor type 10101
C-X-C chemokine receptor type 20101
retinoic acid nuclear receptor alpha variant 11001
histone deacetylase 9 isoform 31001
Tyrosinase0101
NAD(P)H dehydrogenase [quinone] 10001
Chain A, Ferritin light chain1001
USP1 protein, partial2002
DNA polymerase kappa isoform 12002
ATP-binding cassette sub-family C member 30101
Multidrug resistance-associated protein 40101
Nuclear receptor subfamily 1 group I member 20022
Bile salt export pump0101
Cytochrome P450 3A40101
UDP-glucuronosyltransferase 2B70001
Cytochrome P450 3A50101
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Spike glycoprotein1001
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Canalicular multispecific organic anion transporter 10101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Solute carrier organic anion transporter family member 1B10102
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
thioredoxin reductase1001
apical membrane antigen 1, AMA11001
cytochrome P450 family 3 subfamily A polypeptide 41001
EWS/FLI fusion protein1001
pregnane X nuclear receptor1001
G1001
v-jun sarcoma virus 17 oncogene homolog (avian)1001
thyroid hormone receptor beta isoform a1001
serine/threonine-protein kinase PLK11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Rap guanine nucleotide exchange factor 31001
Interferon beta1001
HLA class I histocompatibility antigen, B alpha chain 1001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Inositol hexakisphosphate kinase 11001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
cytochrome P450 2C9, partial1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]
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