Page last updated: 2024-09-27

Hendra Virus Infections

Infections with viruses of the genus HENIPAVIRUS, family PARAMYXOVIRIDAE.

Synonyms(5)

Synonym
Hendra Virus Infections
Nipah Virus Encephalitis
NiV Infection
Henipavirus Infections
Nipah Virus Infection

Research Excerpts

Overview

ExcerptReference
"Henipavirus infections are probably more widespread than it is at presently known and so it is important to have an intense monitoring for these diseases, especially in countries where large-scale deforestation is happening."( Wild, TF, 2009)

Context

ExcerptReference
"NiV infection has not been previously detected in India."( Bellini, WJ; Chadha, MS; Comer, JA; Ksiazek, TG; Lowe, L; Mishra, A; Rollin, PE; Rota, PA, 2006)

Research

Studies (101)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's26 (25.74)18.1394
2010's52 (51.49)28.8240
2020's23 (22.77)9.53
DrugIndicatedRelationship StrengthStudiesTrials
lactic acid0low10
formaldehyde0low20
chloroquine0low30
alanine0low40
adenosine monophosphate0low20
leucine0low10
tryptophan0low10
aziridine0low10
acridines0low10
pyrazines0low20
limestone0low10
tetradecanoylphorbol acetate0low10
ribavirin0low30
bortezomib0low10
phalloidine0low10
favipiravir0low10
phenylephrine hydrochloride0low10
cysteine0low10
sq-233770low10
braco-190low10
clove0low20
sodium hypochlorite0low10
heparitin sulfate0low10
sybr green i0low10
s 89320low20
exudates0low450
tetra(4-n-methylpyridyl)porphine0low10

Protein Targets (362)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Ferritin light chain1001
thioredoxin reductase4004
TDP1 protein5005
Microtubule-associated protein tau3003
Smad31001
aldehyde dehydrogenase 1 family, member A12002
alpha-galactosidase2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
flap endonuclease 13003
DNA polymerase iota isoform a (long)2002
DNA topoisomerase 2-alpha0001
Acetylcholinesterase0101
Chain A, Glycogen Phosphorylase B0011
Chain B, Glycogen Phosphorylase B0011
Chain A, ADP-dependent glucokinase0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, phosphodiesterase-nucleotide pyrophosphatase0101
Chain A, GLYCOGEN PHOSPHORYLASE B0011
Chain B, GLYCOGEN PHOSPHORYLASE B0011
Chain A, GLYCOGEN PHOSPHORYLASE B0011
RAR-related orphan receptor gamma5005
AR protein5005
regulator of G-protein signaling 41001
glucocorticoid receptor [Homo sapiens]4004
estrogen-related nuclear receptor alpha7007
euchromatic histone-lysine N-methyltransferase 24004
v-jun sarcoma virus 17 oncogene homolog (avian)2002
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
Mitogen-activated protein kinase kinase kinase 70011
2'-deoxynucleoside 5'-phosphate N-hydrolase 10101
5'-AMP-activated protein kinase subunit beta-20011
Transient receptor potential cation channel subfamily M member 20101
Alcohol dehydrogenase E chain0101
Alcohol dehydrogenase S chain0101
L-lactate dehydrogenase A chain0112
Adenylate kinase isoenzyme 10001
Fructose-1,6-bisphosphatase 10101
Alkaline phosphatase, tissue-nonspecific isozyme0203
Fructose-1,6-bisphosphatase 10101
2-dehydropantoate 2-reductase0112
Inosine-5'-monophosphate dehydrogenase0101
Cytochrome P450 2C9 0101
Proto-oncogene tyrosine-protein kinase Src0101
Amine oxidase [flavin-containing] B0101
5'-nucleotidase0001
Choline O-acetyltransferase0101
Adenylate kinase 2, mitochondrial0102
GTP:AMP phosphotransferase AK3, mitochondrial0001
Adenosine receptor A10112
Adenylate kinase isoenzyme 1 0102
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Adenylate kinase 2, mitochondrial0001
Glycine--tRNA ligase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Adenosine deaminase-like protein0001
Protease 0112
P2Y purinoceptor 110011
Histamine H3 receptor0101
5'-AMP-activated protein kinase subunit gamma-30011
5'-AMP-activated protein kinase subunit gamma-20011
5'-AMP-activated protein kinase subunit beta-10022
ATP-dependent phosphofructokinase2002
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Carbonic anhydrase 10103
Carbonic anhydrase 20103
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0102
Proton-coupled amino acid transporter 10203
Adenosine deaminase0001
Carbonic anhydrase 40001
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
Fumarate hydratase1001
PPM1D protein2002
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)2002
nuclear receptor subfamily 1, group I, member 32002
progesterone receptor1001
cytochrome P450 family 3 subfamily A polypeptide 43003
EWS/FLI fusion protein1001
retinoic acid nuclear receptor alpha variant 14004
retinoid X nuclear receptor alpha1001
farnesoid X nuclear receptor2002
pregnane X nuclear receptor2002
estrogen nuclear receptor alpha4004
polyprotein1001
peroxisome proliferator-activated receptor delta1001
peroxisome proliferator activated receptor gamma4004
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
caspase-31001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
nuclear receptor subfamily 1, group I, member 21001
Histone H2A.x2002
Caspase-71001
caspase-31001
thyroid hormone receptor beta isoform 22002
heat shock protein beta-11001
nuclear factor erythroid 2-related factor 2 isoform 13003
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
Histone deacetylase 30101
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40303
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120102
Voltage-dependent calcium channel gamma-2 subunit2002
Bile salt export pump0303
Prothrombin0101
Chymotrypsinogen A0101
Interferon beta2002
Cellular tumor antigen p533003
Carbonic anhydrase 30102
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Glutamate receptor 22002
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10102
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50203
Carbonic anhydrase 5A, mitochondrial0102
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
Carbonic anhydrase 70102
26S proteasome regulatory subunit 6B0101
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10101
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90102
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80101
Histone deacetylase 20101
Canalicular multispecific organic anion transporter 10303
ATPase family AAA domain-containing protein 51001
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
Ataxin-23003
Carbonic anhydrase 150102
Histone deacetylase 80101
Histone deacetylase 60101
Carbonic anhydrase 140102
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0102
Telomerase reverse transcriptase0112
Protection of telomeres protein 10101
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0134
Replicase polyprotein 1ab0134
glucose-6-phosphate 1-dehydrogenase isoform b0101
Transmembrane protease serine 20134
Dihydrofolate reductase 0101
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0101
Histidine-rich protein PFHRP-II0102
Procathepsin L0134
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M40101
Cytochrome P450 3A40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0101
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0134
Spike glycoprotein0101
Replicase polyprotein 1ab0235
Muscarinic acetylcholine receptor M10101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
DNA ligase 10101
Muscarinic acetylcholine receptor M30101
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Spike glycoprotein1135
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20202
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Sigma non-opioid intracellular receptor 10101
Angiotensin-converting enzyme 2 0134
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
acetylcholinesterase1001
cytochrome P450 2D61001
thyroid stimulating hormone receptor3003
cellular tumor antigen p53 isoform a1001
Integrin beta-31001
Integrin alpha-IIb1001
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Intestinal-type alkaline phosphatase0202
Large neutral amino acids transporter small subunit 10202
Phospholipase A-2-activating protein0202
Chain A, 2-oxoglutarate Oxygenase2002
glp-1 receptor, partial1001
GALC protein1001
GLI family zinc finger 32002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
IDH11001
beta-2 adrenergic receptor1001
Bloom syndrome protein isoform 12002
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
chromobox protein homolog 12002
geminin2002
Vpr1001
peripheral myelin protein 221001
lamin isoform A-delta103003
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
NS5 0112
interleukin 81001
Thrombopoietin1001
thyroid stimulating hormone receptor2002
arylsulfatase A2002
peripheral myelin protein 22 isoform 12002
nuclear factor erythroid 2-related factor 2 isoform 21001
glycogen synthase kinase-3 beta isoform 10011
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
survival motor neuron protein isoform d1001
cytochrome P450 3A4 isoform 11001
muscarinic acetylcholine receptor M11001
Gamma-aminobutyric acid receptor subunit pi1001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Rap guanine nucleotide exchange factor 31001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Adenosine receptor A30101
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Adenosylhomocysteinase0002
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Adenosine receptor A2a0101
Gamma-aminobutyric acid receptor subunit alpha-61001
Nuclear receptor ROR-gamma2002
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Adenosine receptor A10101
Genome polyprotein0011
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
mitogen-activated protein kinase 11001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
nuclear receptor ROR-gamma isoform 11001
DNA polymerase kappa isoform 11001
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Protein kinase C alpha type0112
Beta-1 adrenergic receptor0101
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
phosphopantetheinyl transferase1001
GLS protein1001
thioredoxin glutathione reductase1001
bromodomain adjacent to zinc finger domain 2B1001
aryl hydrocarbon receptor1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
M-phase phosphoprotein 81001
Dihydrofolate reductase0202
Plasma kallikrein0001
Myeloperoxidase0101
Stromelysin-10101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Carbonic anhydrase0001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3A0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]