Page last updated: 2024-09-28

Hematometra

Blood-filled UTERUS.

Synonyms(1)

Synonym
Hematometra

Research Excerpts

Overview

ExcerptReference
"Hematometra is a condition of retained blood or clot within the uterus."( Jamieson, MA; Rumbolt, D; Russell, EH; Thorne, JG, 2018)

Research

Studies (21)

TimeframeStudies, This Condition (%)All Conditions %
pre-19907 (33.33)23.3326
1990's3 (14.29)12.5806
2000's6 (28.57)18.1394
2010's4 (19.05)28.8240
2020's1 (4.76)9.53
DrugIndicatedRelationship StrengthStudiesTrials
guaifenesin0low10
medroxyprogesterone acetate0low10
medroxyprogesterone0low10
levonorgestrel0low10
technetium0low10
barium sulfate0low10
buserelin0low10
mifepristone0low10
fluorodeoxyglucose f180low10
methotrexate0low10
diethylstilbestrol0low10
nitinol0low10
misoprostol0low10
trelstar0low10

Protein Targets (358)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, Ferritin light chain4004
Luciferase2002
interleukin 82002
acetylcholinesterase1001
glp-1 receptor, partial2002
15-lipoxygenase, partial2002
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma5005
ATAD5 protein, partial6006
USP1 protein, partial6006
GLS protein3003
TDP1 protein7007
GLI family zinc finger 35005
Microtubule-associated protein tau4004
AR protein7007
Smad31001
aldehyde dehydrogenase 1 family, member A14004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
thyroid stimulating hormone receptor1001
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 37007
progesterone receptor6006
regulator of G-protein signaling 42002
cytochrome P450 family 3 subfamily A polypeptide 45005
glucocorticoid receptor [Homo sapiens]5005
retinoic acid nuclear receptor alpha variant 14004
retinoid X nuclear receptor alpha6006
estrogen-related nuclear receptor alpha7007
farnesoid X nuclear receptor6006
pregnane X nuclear receptor5005
estrogen nuclear receptor alpha8008
G6006
cytochrome P450 2D63003
67.9K protein3003
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
IDH14004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
thyroid stimulating hormone receptor3003
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Histone H2A.x4004
cellular tumor antigen p53 isoform a2002
vitamin D3 receptor isoform VDRA5005
thyroid hormone receptor beta isoform a1001
potassium voltage-gated channel subfamily H member 2 isoform d2002
thyroid hormone receptor beta isoform 27007
heat shock protein beta-12002
mitogen-activated protein kinase 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
serine/threonine-protein kinase PLK11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
nuclear factor erythroid 2-related factor 2 isoform 17007
nuclear receptor ROR-gamma isoform 13003
geminin9009
peripheral myelin protein 226006
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 12002
high affinity choline transporter 1 isoform a0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lethal factor (plasmid)1001
lamin isoform A-delta109009
neuropeptide S receptor isoform A4004
Gamma-aminobutyric acid receptor subunit pi2002
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
5-hydroxytryptamine receptor 40202
Nuclear receptor subfamily 1 group I member 20101
Voltage-dependent calcium channel gamma-2 subunit5005
Carbonic anhydrase 10101
Carbonic anhydrase 20112
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 6006
Estrogen receptor1539
Glucocorticoid receptor18314
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Cellular tumor antigen p537007
Integrin beta-32002
Tyrosine-protein kinase Fyn0202
Glycine receptor subunit alpha-10808
Aldo-keto reductase family 1 member B10202
Integrin alpha-IIb2002
Beta-1 adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Polyunsaturated fatty acid 5-lipoxygenase0101
Adenosine receptor A30202
Muscarinic acetylcholine receptor M10202
Polyunsaturated fatty acid lipoxygenase ALOX150202
D(2) dopamine receptor0202
Androgen receptor0707
Gamma-aminobutyric acid receptor subunit beta-12002
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0404
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
Alpha-2C adrenergic receptor0202
Glutamate receptor 25005
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Muscarinic acetylcholine receptor M30202
Glycine receptor subunit beta0808
Substance-K receptor0202
D(1A) dopamine receptor0202
Acetylcholinesterase0202
Glycine receptor subunit alpha-20808
Prostaglandin G/H synthase 10303
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Sodium-dependent noradrenaline transporter 0202
Glycine receptor subunit alpha-30808
Thromboxane-A synthase 0101
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
Adenosine receptor A2a0202
Gamma-aminobutyric acid receptor subunit alpha-62002
Adenosine receptor A10202
Sodium-dependent serotonin transporter0202
Mu-type opioid receptor0404
D(3) dopamine receptor0202
Vasopressin V1a receptor0202
Alpha-synuclein2002
Delta-type opioid receptor0202
Kappa-type opioid receptor0404
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0202
Histamine H2 receptor1001
5-hydroxytryptamine receptor 60202
Nuclear receptor ROR-gamma2002
Spike glycoprotein4004
Estrogen-related receptor gamma0011
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Gamma-aminobutyric acid receptor subunit beta-22002
Disintegrin and metalloproteinase domain-containing protein 171001
Inositol monophosphatase 11001
Sodium-dependent dopamine transporter 0202
Aldehyde oxidase0101
TAR DNA-binding protein 433003
UDP-glucose 4-epimerase0101
Mitogen-activated protein kinase 140202
GABA theta subunit2002
Inositol hexakisphosphate kinase 16006
Estrogen receptor beta1539
Gamma-aminobutyric acid receptor subunit epsilon2002
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Cysteinyl leukotriene receptor 10202
cytochrome P450 2C9, partial6006
SMAD family member 25005
SMAD family member 35005
flap endonuclease 12002
Bile salt export pump0707
Rap guanine nucleotide exchange factor 32002
NFKB1 protein, partial1001
nonstructural protein 13003
arylsulfatase A1001
euchromatic histone-lysine N-methyltransferase 27007
aryl hydrocarbon receptor1001
chromobox protein homolog 16006
transcriptional regulator ERG isoform 34004
importin subunit beta-1 isoform 12002
snurportin-12002
DNA polymerase kappa isoform 12002
muscleblind-like protein 1 isoform 12002
Acid-sensing ion channel 30101
Solute carrier organic anion transporter family member 1A40101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Bile salt export pump0202
Dihydrofolate reductase0304
Epidermal growth factor receptor0101
Fatty acid-binding protein, liver0101
Albumin0112
Albumin0101
Albumin0011
Prostaglandin G/H synthase 10303
Cholinesterase0101
Cytochrome P450 2C9 0303
Fatty acid-binding protein, intestinal0101
Polyunsaturated fatty acid 5-lipoxygenase0102
UDP-glucuronosyltransferase 2B70001
Prostaglandin G/H synthase 10101
Adenosine receptor A10112
Caspase-10101
Adenosine receptor A2a0112
Substance-P receptor0202
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 2 0102
UDP-glucuronosyltransferase 1A30001
Aldo-keto reductase family 1 member C30202
Caspase-30101
Solute carrier organic anion transporter family member 1A10101
Caspase-40101
4-aminobutyrate aminotransferase, mitochondrial0101
Cytochrome P450 2J20101
Caspase-50101
Caspase-90101
Acid-sensing ion channel 10101
Prostaglandin G/H synthase 20202
Mu-type opioid receptor0101
Fatty-acid amide hydrolase 10101
Prostaglandin G/H synthase 20101
Solute carrier family 22 member 60102
Prostaglandin G/H synthase 1 0102
Solute carrier family 22 member 200202
Solute carrier family 22 member 80102
Solute carrier family 22 member 60202
Dehydrogenase/reductase SDR family member 90101
Chain A, Beta-lactamase5005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
nuclear factor erythroid 2-related factor 2 isoform 24004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
DNA polymerase beta3003
DNA polymerase iota isoform a (long)5005
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40405
Progesterone receptor0439
Canalicular multispecific organic anion transporter 10404
ATPase family AAA domain-containing protein 54004
Ataxin-24004
GALC protein1001
PINK12002
Parkin2002
Cytochrome P450 2C190101
Chain A, Cruzipain3003
pregnane X receptor2002
nuclear receptor subfamily 1, group I, member 22002
Sex hormone-binding globulin0011
Mineralocorticoid receptor 1316
Androgen receptor1438
Androgen receptor0011
Histamine H2 receptor0202
5-hydroxytryptamine receptor 1B0101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G2002
Aldo-keto reductase family 1 member C10101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, 2-oxoglutarate Oxygenase1001
acid sphingomyelinase1001
dopamine D1 receptor2002
thioredoxin reductase3003
ClpP1001
phosphopantetheinyl transferase1001
EWS/FLI fusion protein3003
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
Bloom syndrome protein isoform 11001
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
M-phase phosphoprotein 82002
histone acetyltransferase KAT2A isoform 13003
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
ATP-dependent phosphofructokinase2002
Chain A, PROGESTERONE RECEPTOR0101
Glucocorticoid receptor 0101
Fumarate hydratase1001
apical membrane antigen 1, AMA11001
hypothetical protein, conserved1001
polyprotein1001
bromodomain adjacent to zinc finger domain 2B1001
D(1A) dopamine receptor1001
huntingtin isoform 21001
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 11001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Tegument protein VP160011
Glucocorticoid receptor0113
Glucocorticoid receptor0101
Cytochrome P450 3A40202
Coagulation factor VII0101
Cytochrome P450 2C80101
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Tissue factor0101
5-hydroxytryptamine receptor 1A0101
ATP-dependent translocase ABCB10011
D(1A) dopamine receptor1001
Progesterone receptor0011
Sigma non-opioid intracellular receptor 10202
Glucocorticoid receptor0101
thioredoxin glutathione reductase2002
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]