Page last updated: 2024-09-27

Hematoma, Subdural, Spinal

Subdural hematoma of the SPINAL CANAL.

Synonyms(5)

Synonym
Spinal Subdural Hematoma, Traumatic
Hematoma, Subdural, Spinal
Spinal Subdural Hematoma
Subdural Hematoma, Spinal, Traumatic
Traumatic Spinal Subdural Hematoma

Research Excerpts

Context

ExcerptReference
"Spinal subdural hematoma has not previously been reported following rivaroxaban therapy."( Dargazanli, C; Gras-Combe, G; Lonjon, N, 2016)

Treatment

ExcerptReference
"We herein describe a case of acute spinal subdural hematoma (SSDH) during the administration of high-dose corticosteroids and intravenous heparin for the treatment of active lupus nephritis."( Adachi, T; Akita, K; Horii, S; Itoh, K; Kimura, F; Matsumoto, M; Wada, T, 2014)

Research

Studies (23)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's5 (21.74)18.1394
2010's16 (69.57)28.8240
2020's2 (8.70)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
dalteparin0low30
acetaminophen0low10
aspirin0low10
fluoxetine0low10
gabapentin0low10
ticlopidine0low10
tranexamic acid0low10
prednisolone0low10
prednisone0low10
mannitol0low10
methylprednisolone0low30
clopidogrel0low10
vitamin k semiquinone radical0low20
fondaparinux0low10
hydrocodone0low10
rivaroxaban0low40
apixaban0low40
warfarin0low30
vardenafil dihydrochloride0low10

Protein Targets (388)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma4004
ATAD5 protein, partial3003
GLS protein2002
Microtubule-associated protein tau1001
Smad31001
aldehyde dehydrogenase 1 family, member A16006
thyroid stimulating hormone receptor4004
nuclear receptor subfamily 1, group I, member 34004
progesterone receptor7007
EWS/FLI fusion protein8008
retinoic acid nuclear receptor alpha variant 17007
retinoid X nuclear receptor alpha4004
estrogen-related nuclear receptor alpha8008
estrogen nuclear receptor alpha100010
peroxisome proliferator activated receptor gamma3003
aryl hydrocarbon receptor2002
chromobox protein homolog 15005
thyroid hormone receptor beta isoform 25005
peripheral myelin protein 225005
cytochrome P450 3A4 isoform 12002
Gamma-aminobutyric acid receptor subunit pi2204
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Solute carrier family 22 member 60202
Carbonic anhydrase 120101
UDP-glucuronosyltransferase 1A90001
Bile salt export pump0202
Voltage-dependent calcium channel gamma-2 subunit3003
Bile salt export pump011011
Cytochrome P450 2B10001
Cytochrome P450 1A10001
Carbonic anhydrase 10303
Carbonic anhydrase 20303
Myoglobin0101
Cytochrome P450 1A10012
Cytochrome P450 1A20001
Prostaglandin G/H synthase 10202
Carbonic anhydrase 30101
Cytochrome P450 3A40202
Cytochrome P450 2D60303
Cytochrome P450 2C9 0505
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit beta-12204
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit delta2204
Gamma-aminobutyric acid receptor subunit gamma-22215
UDP-glucuronosyltransferase 1-60001
Glutamate receptor 23003
Gamma-aminobutyric acid receptor subunit alpha-52204
Gamma-aminobutyric acid receptor subunit alpha-32204
Arachidonate 5-lipoxygenase-activating protein0101
UDP-glucuronosyltransferase 1A1 0001
Carbonic anhydrase 40101
Prostaglandin G/H synthase 10404
Carbonic anhydrase 60101
Gamma-aminobutyric acid receptor subunit gamma-12204
Gamma-aminobutyric acid receptor subunit alpha-22204
Gamma-aminobutyric acid receptor subunit alpha-42204
Gamma-aminobutyric acid receptor subunit gamma-32204
Gamma-aminobutyric acid receptor subunit alpha-62204
Carbonic anhydrase 5A, mitochondrial0101
Prostaglandin G/H synthase 20304
Carbonic anhydrase 70101
Nuclear receptor ROR-gamma3003
Cytochrome P450 2J20404
Gamma-aminobutyric acid receptor subunit alpha-12316
Gamma-aminobutyric acid receptor subunit beta-32204
Gamma-aminobutyric acid receptor subunit beta-22215
Carbonic anhydrase 90101
GABA theta subunit2204
Canalicular multispecific organic anion transporter 10606
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Gamma-aminobutyric acid receptor subunit epsilon2204
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
toxin B0001
Chain A, Coagulation factor X (EC 3.4.21.6) (Stuart factor) (Stuart-Prower factor)0101
Coagulation factor X0101
Prothrombin0202
Coagulation factor X0505
Trypsin-10101
Trypsin-20101
Trypsin-30101
Spike glycoprotein3003
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, 2-oxoglutarate Oxygenase2002
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 81001
thioredoxin reductase4004
AR protein8008
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 45005
glucocorticoid receptor [Homo sapiens]8008
cytochrome P450 2D63003
glucocerebrosidase1001
peroxisome proliferator-activated receptor delta2002
Rac1 protein0011
IDH12002
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
euchromatic histone-lysine N-methyltransferase 27007
Bloom syndrome protein isoform 13003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
DNA polymerase iota isoform a (long)3003
DNA polymerase kappa isoform 12002
muscarinic acetylcholine receptor M12002
lethal factor (plasmid)1001
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0101
Fatty acid-binding protein, liver0202
Integrin beta-30101
Myeloperoxidase0101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb0101
Glutathione hydrolase 1 proenzyme0101
Adenosine receptor A10101
Adenosine receptor A2a0101
Substance-P receptor0101
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20101
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Sigma non-opioid intracellular receptor 10617
Sigma non-opioid intracellular receptor 10213
Potassium channel subfamily K member 30202
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
nonstructural protein 12002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
geminin6006
Cytochrome P450 2C80303
Cytochrome P450 2B60303
Liver carboxylesterase 10001
Sodium-dependent serotonin transporter0426
Cytochrome P450 2C190404
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120101
Luciferase2002
TDP1 protein5005
pregnane X nuclear receptor7007
potassium voltage-gated channel subfamily H member 2 isoform d4004
Solute carrier family 22 member 1 0202
Nuclear receptor subfamily 1 group I member 20022
ATP-dependent translocase ABCB10202
D(2) dopamine receptor0101
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0213
Kappa-type opioid receptor0101
Histamine H1 receptor0101
Mu-type opioid receptor0314
D(3) dopamine receptor0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Kappa-type opioid receptor0303
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20303
Sigma non-opioid intracellular receptor 10303
GLI family zinc finger 36006
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)3003
regulator of G-protein signaling 43003
G3003
caspase-31001
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x1001
Caspase-71001
NPC intracellular cholesterol transporter 1 precursor1001
D(1A) dopamine receptor2002
caspase-31001
huntingtin isoform 21001
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 11001
nuclear factor erythroid 2-related factor 2 isoform 13003
lamin isoform A-delta108008
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 40202
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 3003
Albumin0022
Cellular tumor antigen p535005
Sodium channel protein type 1 subunit alpha0101
Aldo-keto reductase family 1 member B10202
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0303
Muscarinic acetylcholine receptor M10202
Angiotensin-converting enzyme0202
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2A0202
Gamma-aminobutyric acid receptor subunit alpha-10213
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0404
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20213
Alpha-2B adrenergic receptor0101
Muscarinic acetylcholine receptor M30202
Acetylcholinesterase0101
Alpha-2C adrenergic receptor0101
Acetylcholinesterase0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0202
Sodium-dependent noradrenaline transporter 0213
Sodium-dependent dopamine transporter0202
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Gamma-aminobutyric acid receptor subunit beta-30213
5-hydroxytryptamine receptor 2B0202
Gamma-aminobutyric acid receptor subunit alpha-50213
Sodium-dependent serotonin transporter0202
Gamma-aminobutyric acid receptor subunit alpha-30213
Alpha-1A adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40213
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0202
Gastrin/cholecystokinin type B receptor 0101
Sodium-dependent dopamine transporter 0213
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Gamma-aminobutyric acid receptor subunit alpha-60213
Cytochrome P450 1B10101
Sigma intracellular receptor 20101
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0101
Nuclear receptor subfamily 3 group C member 3 0202
Beta-2 adrenergic receptor0101
Gamma-aminobutyric acid receptor subunit gamma-10202
Inositol hexakisphosphate kinase 13003
Ataxin-23003
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0101
Histamine H3 receptor0101
cytochrome P450 2C9, partial3003
USP1 protein, partial3003
thioredoxin glutathione reductase3003
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
survival motor neuron protein isoform d1001
Voltage-dependent calcium channel subunit alpha-2/delta-10101
ATP-dependent phosphofructokinase2002
Chain A, Ferritin light chain3003
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B2002
arylsulfatase A1001
thyroid hormone receptor beta isoform a2002
transcriptional regulator ERG isoform 31001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
histone acetyltransferase KAT2A isoform 12002
neuropeptide S receptor isoform A1001
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 432002
Histone deacetylase 10101
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
phosphopantetheinyl transferase1001
Mas-related G-protein coupled receptor member X20011
activating transcription factor 61001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
acetylcholinesterase2002
hypoxia-inducible factor 1 alpha subunit2002
PPM1D protein2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
nuclear receptor subfamily 1, group I, member 22002
nuclear factor erythroid 2-related factor 2 isoform 23003
muscleblind-like protein 1 isoform 11001
Glucocorticoid receptor06213
Glycine receptor subunit alpha-10606
Androgen receptor0303
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
ATPase family AAA domain-containing protein 52002
Nuclear receptor subfamily 1 group I member 20011
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
pregnane X receptor1001
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
vitamin D3 receptor isoform VDRA2002
nuclear receptor ROR-gamma isoform 11001
Chain A, Activated Factor Xa Heavy Chain0101
Coagulation factor XII0101
Suppressor of tumorigenicity 14 protein0101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
glp-1 receptor, partial1001
thyroid stimulating hormone receptor1001
cytochrome P450 2D6 isoform 11001
cytochrome P450 2C19 precursor1001
heat shock protein beta-11001
Alpha-2C adrenergic receptor0202
Disintegrin and metalloproteinase domain-containing protein 171001
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
Chain A, Beta-lactamase2002
Rap guanine nucleotide exchange factor 31001
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]