Page last updated: 2024-09-27

Hemangioma, Capillary

A dull red, firm, dome-shaped hemangioma, sharply demarcated from surrounding skin, usually located on the head and neck, which grows rapidly and generally undergoes regression and involution without scarring. It is caused by proliferation of immature capillary vessels in active stroma, and is usually present at birth or occurs within the first two or three months of life. (Dorland, 27th ed)

Synonyms(1)

Synonym
Hemangioma, Capillary

Research Excerpts

Overview

ExcerptReference
"Cutaneous capillary hemangioma is usually a sporadic condition."( Minzter, R; Shields, CL; Shields, JA; Singh, AD, 2000)
"Infantile or capillary hemangioma is the most common vascular tumor of childhood."( Frei-Jones, M; Leonard, JR; McKinstry, RC; Park, TS; Perry, A; Rubin, JB, 2008)
"Capillary hemangioma is considered to be one of the most widespread (frequently occurring) vascular ENT tumours."( Antoniv, TV, 2012)
"Capillary hemangioma is the most common benign tumor of eyelids and orbit in children."( Rizvi, SA; Rizvi, SW; Sharma, R; Yusuf, F, 2015)

Treatment

ExcerptReference
"In 2008, the effect of propranolol for treating capillary hemangiomas was demonstrated."( Albuquerque, JC; Bastos, MV; Felix, FH; Félix, JA; Fontenele, JB; Magalhães, RA; Trompieri, NM, 2014)

Research

Studies (408)

TimeframeStudies, This Condition (%)All Conditions %
pre-19904 (0.98)23.3326
1990's38 (9.31)12.5806
2000's68 (16.67)18.1394
2010's203 (49.75)28.8240
2020's95 (23.28)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbon monoxide0low10
salicylic acid0low100
albuterol0low10
aspirin0low30
atenolol0medium122
azathioprine0low10
betaxolol0low10
carteolol0low10
pentetic acid0low30
fluorouracil0medium11
furosemide0low20
gentamicin0low10
iohexol0low10
2-propanol0low70
apnea0low20
pentoxifylline0low10
propranolol0medium20510
temozolomide0low10
thalidomide0low10
ticlopidine0low20
tropicamide0low10
mitomycin0low10
prednisolone0low140
prednisone0low50
triamcinolone diacetate0low10
perflutren0low10
triamcinolone acetonide0medium101
methylprednisolone0low80
diatrizoate meglumine0low10
pyrazines0low10
betamethasone0low110
reticulin0low10
sulfur hexafluoride0low10
neodymium0low20
ruthenium0low10
technetium0low20
titanium0low10
gadolinium0low30
yttrium0low30
triamcinolone0low110
timolol0medium424
sq-117250medium31
propiconazole0low90
captopril0low10
imiquimod0medium31
3-iodobenzylguanidine0low10
betamethasone sodium phosphate0low30
fluorodeoxyglucose f180low10
fibrinogen0low10
yttrium radioisotopes0low10
bosentan anhydrous0low20
betamethasone acetate phosphate0low10
imatinib mesylate0low30
technetium tc 99m pentetate0low20
angiotensin ii0low20
deoxycholic acid0low20
cortisone0low10
bortezomib0low10
inositol 3-phosphate0low50
mupirocin0low10
bromochloroacetic acid0low20
polidocanol0low30
leuprolide0low10
curcumin0low10
osteoprotegerin0low10
ethamolin0low30
phenylephrine hydrochloride0low30
sirolimus0low30
clobetasol0low20
aluminum0low10
strontium0low10
phosphorus0low10
strontium radioisotopes0low10
gadolinium dtpa0low60
brimonidine tartrate0low10
indocyanine green0low120
acid phosphatase0low10
bleomycetin0medium21
macitentan0low10
angiotensinogen0low10
sodium tetradecyl sulfate0low10
cardiovascular agents0low10
apatinib0low10
natriuretic peptide, brain0low20
warfarin0low10
almagate0medium11
cyclin d10low10
lewis x antigen0low20
adrenomedullin0low10
technetium tc 99m medronate0low10
rifampin0low10
dacarbazine0low10
sildenafil citrate0low20
eye0low20
phosphorus radioisotopes0low10

Protein Targets (961)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit100010
RAR-related orphan receptor gamma240024
GLI family zinc finger 3240024
AR protein370037
aldehyde dehydrogenase 1 family, member A1150015
retinoic acid nuclear receptor alpha variant 1220022
retinoid X nuclear receptor alpha160016
estrogen nuclear receptor alpha380038
peroxisome proliferator-activated receptor delta150015
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a200020
activating transcription factor 66006
v-jun sarcoma virus 17 oncogene homolog (avian)120012
Histone H2A.x6006
thyroid hormone receptor beta isoform a9009
heat shock protein beta-1110011
nuclear factor erythroid 2-related factor 2 isoform 1220022
lamin isoform A-delta10200020
Voltage-dependent calcium channel gamma-2 subunit140014
Glutamate receptor 2140014
dopamine D1 receptor3003
thioredoxin reductase190019
GLS protein6006
Thrombopoietin3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
cytochrome P450 2D6 isoform 14004
cytochrome P450 2C19 precursor3003
ras-related protein Rab-9A1001
histone acetyltransferase KAT2A isoform 16006
lethal factor (plasmid)3003
POU domain, class 2, transcription factor 10001
Spike glycoprotein120012
ATP-dependent phosphofructokinase8008
glp-1 receptor, partial7007
regulator of G-protein signaling 46006
estrogen-related nuclear receptor alpha270027
NPYLR7B0011
arylsulfatase A130013
euchromatic histone-lysine N-methyltransferase 2220022
thyroid stimulating hormone receptor100010
flap endonuclease 15005
peripheral myelin protein 22100010
ATP-binding cassette sub-family C member 3025025
Multidrug resistance-associated protein 4025025
Bile salt export pump034034
Beta-2 adrenergic receptor08513
Beta-1 adrenergic receptor08614
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0303
Beta-3 adrenergic receptor0448
Delta-type opioid receptor0011
10 kDa heat shock protein, mitochondrial0303
Thiosulfate sulfurtransferase0303
Beta-2 adrenergic receptor 0024
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Beta-2 adrenergic receptor0269
Canalicular multispecific organic anion transporter 1024024
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain5005
Chain A, Apolipoprotein0011
15-lipoxygenase, partial5005
ATAD5 protein, partial110011
cytochrome P450 family 3 subfamily A polypeptide 4220022
EWS/FLI fusion protein140015
nonstructural protein 15005
glucocorticoid receptor [Homo sapiens]290029
D(1A) dopamine receptor4004
chromobox protein homolog 1110011
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
geminin250025
Rap guanine nucleotide exchange factor 32002
Plasminogen0213
Proton-coupled amino acid transporter 10101
glucocerebrosidase3003
DNA polymerase kappa isoform 16006
Atrial natriuretic peptide receptor 30101
Type-1A angiotensin II receptor 0213
Type-1 angiotensin II receptor0011
Type-1B angiotensin II receptor0202
Type-1 angiotensin II receptor0336
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0202
Vascular endothelial growth factor receptor 20101
TDP1 protein250025
Microtubule-associated protein tau7007
Bloom syndrome protein isoform 18008
neuropeptide S receptor isoform A2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, 2-oxoglutarate Oxygenase9009
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 86006
thyroid stimulating hormone receptor7007
hypothetical protein, conserved1001
cytochrome P450 2D6100010
Rac1 protein0011
IDH1110011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
DNA polymerase iota isoform a (long)100010
muscarinic acetylcholine receptor M15005
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60303
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0213
Carbonic anhydrase 10709
Carbonic anhydrase 20709
Fatty acid-binding protein, liver0404
Integrin beta-31102
Myeloperoxidase0202
Prostaglandin G/H synthase 10303
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb1102
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10404
Adenosine receptor A10101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin G/H synthase 20606
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma5005
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-172413
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200202
Solute carrier family 22 member 60202
Sigma non-opioid intracellular receptor 10415
Sigma non-opioid intracellular receptor 10011
Beta-1 adrenergic receptor 0146
Gamma-aminobutyric acid receptor subunit pi71412
Urease0101
Gamma-aminobutyric acid receptor subunit beta-171412
Gamma-aminobutyric acid receptor subunit delta71412
Gamma-aminobutyric acid receptor subunit gamma-271412
5-hydroxytryptamine receptor 1A05410
Gamma-aminobutyric acid receptor subunit alpha-571412
Gamma-aminobutyric acid receptor subunit alpha-371412
Gamma-aminobutyric acid receptor subunit gamma-171412
Gamma-aminobutyric acid receptor subunit alpha-271412
Alpha-1D adrenergic receptor0315
Gamma-aminobutyric acid receptor subunit alpha-471412
Gamma-aminobutyric acid receptor subunit gamma-371412
Gamma-aminobutyric acid receptor subunit alpha-671412
Alpha-1A adrenergic receptor0225
Alpha-1B adrenergic receptor0113
Gamma-aminobutyric acid receptor subunit beta-371412
Gamma-aminobutyric acid receptor subunit beta-271412
TAR DNA-binding protein 438008
GABA theta subunit71412
Gamma-aminobutyric acid receptor subunit epsilon71412
acetylcholinesterase7007
phosphopantetheinyl transferase7007
SMAD family member 27007
Fumarate hydratase4004
SMAD family member 37007
thioredoxin glutathione reductase5005
nuclear receptor subfamily 1, group I, member 3170017
farnesoid X nuclear receptor120012
pregnane X nuclear receptor220022
G8008
polyprotein4004
P531001
peroxisome proliferator activated receptor gamma170017
aryl hydrocarbon receptor140014
peripheral myelin protein 22 isoform 17007
hemoglobin subunit beta3003
cellular tumor antigen p53 isoform a2002
thyroid hormone receptor beta isoform 2180018
survival motor neuron protein isoform d7007
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 84004
muscleblind-like protein 1 isoform 16006
Bile salt export pump010010
Interferon beta120012
HLA class I histocompatibility antigen, B alpha chain 8008
Cellular tumor antigen p53180018
Inositol hexakisphosphate kinase 18008
ATPase family AAA domain-containing protein 5120012
Ataxin-2130013
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial8008
pregnane X receptor6006
progesterone receptor180018
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
nuclear receptor subfamily 1, group I, member 29009
nuclear factor erythroid 2-related factor 2 isoform 29009
galanin receptor type 30101
Glucocorticoid receptor014221
Glycine receptor subunit alpha-1014014
Glycine receptor subunit beta014014
Glycine receptor subunit alpha-2014014
Glycine receptor subunit alpha-3014014
ORF730011
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
Cytochrome P450 2D60404
Beta-1 adrenergic receptor0326
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
PPM1D protein3003
caspase 7, apoptosis-related cysteine protease4004
estrogen receptor 2 (ER beta)120012
caspase-34004
Caspase-71001
caspase-31001
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
Histone deacetylase 30202
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120406
Prothrombin0202
Chymotrypsinogen A0101
Carbonic anhydrase 30304
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10102
Carbonic anhydrase 40305
Carbonic anhydrase 60305
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50304
Carbonic anhydrase 5A, mitochondrial0305
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
Carbonic anhydrase 70305
26S proteasome regulatory subunit 6B0112
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10303
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90406
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80101
Histone deacetylase 20303
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
Carbonic anhydrase 150202
Histone deacetylase 80303
Histone deacetylase 60202
Carbonic anhydrase 140305
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0305
vitamin D3 receptor isoform VDRA4004
nuclear receptor ROR-gamma isoform 18008
Nuclear receptor subfamily 1 group I member 20055
Endothelin receptor type B0202
Endothelin receptor type B0314
Endothelin-1 receptor0415
Endothelin-1 receptor0213
Endothelin receptor type B0011
Deoxyhypusine synthase0101
Sodium/bile acid cotransporter0415
Endothelin-1 receptor0101
Chain A, angiotensin converting enzyme0101
Chain A, angiotensin converting enzyme0101
Metallo-beta-lactamase type 20112
transient receptor potential cation channel subfamily V member 11001
Renin0101
Neprilysin0101
Neprilysin0101
Leukotriene A-4 hydrolase0213
EEF1AKMT4-ECE2 readthrough transcript protein0101
Angiotensin-converting enzyme 0213
Angiotensin-converting enzyme0203
Leukotriene A-4 hydrolase0101
Thymidine phosphorylase0011
Endothelin-converting enzyme 10101
Succinyl-diaminopimelate desuccinylase0202
Angiotensin-converting enzyme0202
Solute carrier family 15 member 10101
Beta-lactamase TEM0101
Mu-type opioid receptor0011
Beta-lactamase 0203
Beta-lactamase 0202
Angiotensin-converting enzyme 2 0101
Beta-lactamase class B VIM-2 0112
endonuclease IV5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
atrial natriuretic peptide receptor 1 precursor1001
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0202
Potassium voltage-gated channel subfamily A member 10011
Multidrug and toxin extrusion protein 10202
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, Cruzipain2002
Luciferase7007
Nrf21001
USP1 protein, partial7007
alkaline phosphatase, intestinal0101
Smad34004
apical membrane antigen 1, AMA12002
PINK11001
Parkin1001
bromodomain adjacent to zinc finger domain 2B3003
toll-like receptor 90101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
TPA: protein transporter TIM100101
thyrotropin-releasing hormone receptor2002
lysosomal alpha-glucosidase preproprotein2002
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0101
polyunsaturated fatty acid lipoxygenase ALOX121001
perilipin-50101
intestinal alkaline phosphatase precursor0101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d6006
transcriptional regulator ERG isoform 33003
huntingtin isoform 23003
importin subunit beta-1 isoform 11001
pyruvate kinase PKM isoform a1001
DNA polymerase beta2002
mitogen-activated protein kinase 11001
nuclear factor NF-kappa-B p105 subunit isoform 11001
snurportin-11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
alkaline phosphatase, germ cell type preproprotein0101
caspase-1 isoform alpha precursor1001
hypothetical protein SA14220101
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Prostaglandin E synthase0101
Polyunsaturated fatty acid lipoxygenase ALOX15B4004
Acetylcholinesterase0101
Lysine-specific histone demethylase 1A0101
D-amino-acid oxidase0101
Phospholipase A20101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10303
Amyloid-beta precursor protein1103
Neuronal proto-oncogene tyrosine-protein kinase Src 0101
Cholinesterase0202
Heme oxygenase 1 0101
Glutathione S-transferase P0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Microtubule-associated protein tau0102
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Tissue factor0101
Tyrosinase0101
Aminopeptidase N0101
Aminopeptidase N0101
Alpha-1B adrenergic receptor0213
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20202
Glycogen synthase kinase-3 beta0101
Amine oxidase [flavin-containing] A0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Acetylcholinesterase0303
Heme oxygenase 20101
Alpha-1D adrenergic receptor0213
Amine oxidase [flavin-containing] B0202
Voltage-dependent L-type calcium channel subunit alpha-1D0101
17-beta-hydroxysteroid dehydrogenase type 20101
Alpha-synuclein2215
Alpha-1A adrenergic receptor0213
Histamine H2 receptor4004
Glycogen synthase kinase-3 beta0112
Caspase-71001
Histone deacetylase 40101
Beta-secretase 10101
Guanine nucleotide-binding protein G2002
Cholinesterase0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
Serine/threonine-protein kinase PAK 10101
5-hydroxytryptamine receptor 40011
Nuclear factor erythroid 2-related factor 20011
Thioredoxin reductase 1, cytoplasmic0101
Thioredoxin reductase 30101
Sortase A0101
Histone deacetylase 70101
CREB-binding protein0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30202
Cysteine protease 0101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
NACHT, LRR and PYD domains-containing protein 3 0101
Thioredoxin reductase 2, mitochondrial0101
CDGSH iron-sulfur domain-containing protein 10404
Histone deacetylase 90101
Broad substrate specificity ATP-binding cassette transporter ABCG20404
Histone deacetylase 50101
Lymphocyte antigen 960011
Beta lactamase (plasmid)0101
Matrix metalloproteinase-90101
Inositol monophosphatase 12002
Isocitrate lyase0202
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Vitamin D3 receptor0112
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10011
Bile acid receptor0112
Hsf1 protein0011
Enoyl-[acyl-carrier-protein] reductase [NADH]0204
Pantothenate synthetase0202
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
67.9K protein5005
serine/threonine-protein kinase mTOR isoform 12002
Vpr2002
Solute carrier family 22 member 80001
Thymidylate synthase0101
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Albumin0235
Glucose-6-phosphate 1-dehydrogenase0101
Cytochrome P450 2C9 0808
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Cytochrome P450 2J20505
6-phosphogluconate dehydrogenase, decarboxylating0101
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Carbonic anhydrase 130204
G-protein coupled receptor 350112
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
DNA repair protein RAD52 homolog isoform a0001
Tyrosine-protein kinase ABL10224
Cytochrome P450 3A40405
Cytochrome P450 2C80304
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0022
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50001
Histamine H2 receptor0202
Adenosine receptor A2a0314
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20203
Cytochrome P450 1A20202
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Cytochrome P450 2C190606
Endonuclease III-like protein 10101
DNA gyrase subunit B0202
DNA gyrase subunit A0202
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0101
Endonuclease 8-like 10101
Gonadotropin-releasing hormone receptor0101
Gonadotropin-releasing hormone receptor0202
Androgen receptor0303
Nuclear receptor subfamily 1 group I member 20011
Indoleamine 2,3-dioxygenase 10101
Chain A, Isoleucyl-tRNA synthetase0101
heat shock protein 900011
streptokinase A precursor0011
twin arginine protein translocation system - TatA protein0001
Isoleucine--tRNA ligase0101
Estrogen receptor0011
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase0101
Estrogen receptor beta0011
Atrial natriuretic peptide receptor 10101
GALC protein2002
NFKB1 protein, partial3003
vasopressin V1b receptor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0202
Tumor necrosis factor0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Adenosine receptor A2b0101
Disintegrin and metalloproteinase domain-containing protein 172002
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Chitotriosidase-10213
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Endochitinase B10213
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, Beta-lactamase3003
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Solute carrier family 22 member 1 0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
5-hydroxytryptamine receptor 40202
Muscarinic acetylcholine receptor M20314
ATP-dependent translocase ABCB10303
5-hydroxytryptamine receptor 1A0101
Alpha-2A adrenergic receptor0326
Adenosine receptor A30112
Beta-2 adrenergic receptor0203
Muscarinic acetylcholine receptor M10314
D(2) dopamine receptor0112
Alpha-2B adrenergic receptor0214
Alpha-2C adrenergic receptor0326
D(3) dopamine receptor0101
Alpha-2B adrenergic receptor0011
Muscarinic acetylcholine receptor M30314
D(1A) dopamine receptor0112
Alpha-2C adrenergic receptor0011
Alpha-2A adrenergic receptor0011
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 2A0213
5-hydroxytryptamine receptor 2C0213
5-hydroxytryptamine receptor 1B0404
Neuromedin-K receptor0011
Sodium-dependent serotonin transporter0202
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Mu-type opioid receptor0112
Vasopressin V1a receptor0112
Delta-type opioid receptor0112
Kappa-type opioid receptor0112
5-hydroxytryptamine receptor 2B0213
5-hydroxytryptamine receptor 60213
5-hydroxytryptamine receptor 70101
Beta-2 adrenergic receptor0101
Potassium voltage-gated channel subfamily H member 20101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Nuclear receptor subfamily 2 group E member 10022
DNA-directed RNA polymerase subunit beta0101
Solute carrier organic anion transporter family member 1A40102
Solute carrier organic anion transporter family member 2B1 0202
NH(3)-dependent NAD(+) synthetase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cytochrome P450 2B60213
Arylacetamide deacetylase0102
Caspase-10101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20102
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
Lanosterol 14-alpha demethylase0101
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10305
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10012
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Solute carrier family 22 member 80101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20012
5'-AMP-activated protein kinase subunit beta-10001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0112
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20112
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
polyadenylate-binding protein 10101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 11001
Solute carrier organic anion transporter family member 1A50001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
procathepsin L isoform 1 preproprotein0101
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]