| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| TDP1 protein | 3 | 0 | 0 | 3 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 3 | 0 | 5 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit B | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit B | 0 | 1 | 0 | 2 |
| DNA gyrase subunit A | 0 | 1 | 0 | 3 |
| DNA gyrase subunit B | 0 | 1 | 0 | 3 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 1 |
| DNA topoisomerase 4 subunit B | 0 | 1 | 0 | 2 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| DNA topoisomerase 2-alpha | 0 | 1 | 0 | 4 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 3 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 3 | 0 | 5 |
| DNA gyrase subunit A | 0 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 3 | 0 | 5 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Multidrug resistance protein MdtK | 0 | 0 | 1 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 3 | 1 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 3 | 0 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 3 | 1 | 6 |
| DNA gyrase subunit B | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 3 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 1 |
| DNA topoisomerase 4 subunit B | 0 | 1 | 0 | 1 |
| Integrase | 0 | 1 | 0 | 1 |
| GABA theta subunit | 2 | 3 | 0 | 5 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 3 | 0 | 5 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-3 | 0 | 0 | 1 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| Hsf1 protein | 0 | 0 | 1 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 2 | 0 | 0 | 2 |
| geminin | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit rho-1 | 0 | 0 | 2 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit rho-2 | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent taurine transporter | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 1 | 2 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 1 | 2 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 0 | 0 | 1 |
| 4-aminobutyrate aminotransferase, mitochondrial | 0 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Histone deacetylase 1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 1 | 2 |
| Sterol O-acyltransferase 1 | 0 | 0 | 1 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 0 | 1 | 1 |
| Histone deacetylase 7 | 0 | 1 | 0 | 1 |
| Histone deacetylase 2 | 0 | 1 | 0 | 1 |
| Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
| Histone deacetylase 11 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| Histone deacetylase 8 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 0 | 1 | 1 |
| Platelet glycoprotein VI | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 0 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 0 | 1 | 1 |
| Histone deacetylase 9 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| Histone deacetylase 5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid type B receptor subunit 1 | 0 | 1 | 0 | 1 |
| Chain A, HISTIDINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Carbonic anhydrase 12 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 1 | 0 | 0 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 0 | 0 | 2 |
| Plasma kallikrein | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 0 | 0 | 1 |
| Histidine-binding periplasmic protein | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 0 | 0 | 1 |
| Adenosine receptor A1 | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 0 | 1 |
| Adenosine receptor A2a | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| Glutaminyl-peptide cyclotransferase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 0 | 1 |
| Carbonic anhydrase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 3 | 0 | 0 | 3 |
| AR protein | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Glucocorticoid receptor | 0 | 4 | 1 | 10 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Androgen receptor | 0 | 3 | 0 | 3 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| polyadenylate-binding protein 1 | 0 | 1 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| bcl-2-related protein A1 | 0 | 1 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| P2X purinoceptor 4 | 0 | 1 | 0 | 1 |
| luciferase | 0 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 2 | 0 | 2 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Progesterone receptor | 0 | 2 | 0 | 3 |
| Glucocorticoid receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 0 | 1 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 2 | 1 | 3 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Glutamine synthetase | 0 | 0 | 1 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Histamine H1 receptor | 0 | 0 | 1 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Nociceptin receptor | 0 | 0 | 1 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 2 | 0 | 2 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Glutamate 5-kinase | 0 | 0 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter A | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter B(0) | 0 | 1 | 0 | 1 |
| Amino acid transporter | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |