A bony proliferation and articular degeneration of the first METATARSOPHALANGEAL JOINT that is characterized by pain and a progressive decrease in the dorsiflexion range of motion.
| Synonym |
|---|
| Hallux Limitus |
| Timeframe | Studies, This Condition (%) | All Conditions % |
|---|
| Drug | Indicated | Relationship Strength | Studies | Trials |
|---|
| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|---|---|---|---|
| GLS protein | 1 | 0 | 0 | 1 |
| TDP1 protein | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 1 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Stromelysin-1 | 0 | 1 | 0 | 1 |
| Matrilysin | 0 | 1 | 0 | 1 |
| Multidrug transporter MdfA | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Protein mono-ADP-ribosyltransferase PARP15 | 0 | 1 | 0 | 1 |
| Protein-arginine deiminase type-4 | 0 | 2 | 0 | 2 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | ||||