Page last updated: 2024-09-28

Granuloma of Larynx

A tumor-like nodule or mass of inflammatory granulation tissue projecting into the lumen of the LARYNX.

Synonyms(3)

Synonym
Granuloma, Laryngeal
Granuloma of Larynx
Laryngeal Granuloma

Research Excerpts

Research

Studies (22)

TimeframeStudies, This Condition (%)All Conditions %
pre-19902 (9.09)23.3326
1990's3 (13.64)12.5806
2000's9 (40.91)18.1394
2010's7 (31.82)28.8240
2020's1 (4.55)9.53
DrugIndicatedRelationship StrengthStudiesTrials
isoniazid0low10
mesalamine0low10
metronidazole0low10
rabeprazole0low10
sevoflurane0low10
prednisone0low20
methylprednisolone acetate0low10
triamcinolone acetonide0low10
methylprednisolone0low10
acetylcysteine0low10
ethambutol0low10
titanium0low10
zinc sulfate0low20
triamcinolone0low10
amoxicillin0low10
fluorodeoxyglucose f180low10
clarithromycin0low10
potassium titanylphosphate0low10
acriflavine0low10
terbinafine0low10
pulmicort0low10
tranilast0low10
etretinate0low10
isotretinoin0low10
(9R)-9-chloro-11,17-dihydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one0low10
rifampin0low10

Protein Targets (345)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
IDH14004
chromobox protein homolog 14004
geminin130013
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
acetylcholinesterase3003
dopamine D1 receptor2002
15-lipoxygenase, partial3003
pregnane X receptor2002
phosphopantetheinyl transferase3003
RAR-related orphan receptor gamma100010
USP1 protein, partial6006
NFKB1 protein, partial4004
Microtubule-associated protein tau3003
Thrombopoietin3003
AR protein150015
regulator of G-protein signaling 42002
glucocorticoid receptor [Homo sapiens]140014
retinoic acid nuclear receptor alpha variant 1100010
retinoid X nuclear receptor alpha100010
farnesoid X nuclear receptor5005
estrogen nuclear receptor alpha180018
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
arylsulfatase A3003
euchromatic histone-lysine N-methyltransferase 29009
Bloom syndrome protein isoform 13003
D(1A) dopamine receptor1001
thyroid hormone receptor beta isoform a4004
thyroid hormone receptor beta isoform 2100010
heat shock protein beta-15005
flap endonuclease 11001
peripheral myelin protein 223003
survival motor neuron protein isoform d3003
muscarinic acetylcholine receptor M12002
Histone deacetylase 30101
Solute carrier family 22 member 60101
Histone deacetylase 40101
Guanine nucleotide-binding protein G1001
Histone deacetylase 10101
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Ataxin-28008
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
ATP-dependent phosphofructokinase4004
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
hypoxia-inducible factor 1 alpha subunit6006
SMAD family member 25005
Fumarate hydratase1001
SMAD family member 35005
TDP1 protein100010
GLI family zinc finger 3110011
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)5005
nuclear receptor subfamily 1, group I, member 35005
progesterone receptor9009
cytochrome P450 family 3 subfamily A polypeptide 49009
estrogen-related nuclear receptor alpha110011
pregnane X nuclear receptor130013
cytochrome P450 2D65005
polyprotein1001
67.9K protein3003
peroxisome proliferator-activated receptor delta6006
peroxisome proliferator activated receptor gamma5005
caspase-31001
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
thyroid stimulating hormone receptor3003
activating transcription factor 65005
thyrotropin-releasing hormone receptor1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x4004
potassium voltage-gated channel subfamily H member 2 isoform d4004
nuclear factor erythroid 2-related factor 2 isoform 1100010
Voltage-dependent calcium channel gamma-2 subunit5005
Interferon beta7007
Cellular tumor antigen p539009
Glutamate receptor 25005
Spike glycoprotein5005
ATPase family AAA domain-containing protein 57007
Chain A, Beta-lactamase3003
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
apical membrane antigen 1, AMA11001
Beta-lactamase 0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)2002
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
DNA polymerase kappa isoform 12002
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012012
Bile salt export pump0404
Bile salt export pump013013
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Cytochrome P450 2C9 0303
Beta-lactamase0001
Kappa-type opioid receptor0001
Solute carrier family 15 member 10101
Solute carrier family 15 member 10101
Cytochrome P450 2J20303
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Canalicular multispecific organic anion transporter 1012012
importin subunit beta-1 isoform 12002
mitogen-activated protein kinase 13003
snurportin-12002
GTP-binding nuclear protein Ran isoform 12002
streptokinase A precursor0011
ATP-dependent translocase ABCB10101
Cytochrome P450 3A40202
Potassium voltage-gated channel subfamily H member 20101
Solute carrier organic anion transporter family member 1B30305
Solute carrier organic anion transporter family member 1B10305
Enoyl-[acyl-carrier-protein] reductase [NADH]0204
Pantothenate synthetase0202
G4004
HLA class I histocompatibility antigen, B alpha chain 4004
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
Luciferase4004
GLS protein3003
EWS/FLI fusion protein2002
bromodomain adjacent to zinc finger domain 2B3003
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
cytochrome P450 2D6 isoform 11001
nuclear receptor ROR-gamma isoform 16006
cytochrome P450 3A4 isoform 15005
histone acetyltransferase KAT2A isoform 12002
Gamma-aminobutyric acid receptor subunit pi5005
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20101
Myeloperoxidase0101
Cytochrome P450 1A20101
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Gamma-aminobutyric acid receptor subunit beta-15005
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Gamma-aminobutyric acid receptor subunit alpha-65005
Cytochrome P450 2C190101
Gamma-aminobutyric acid receptor subunit alpha-15005
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
Endonuclease III-like protein 10101
DNA gyrase subunit B0202
DNA gyrase subunit A0202
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0101
GABA theta subunit5005
Endonuclease 8-like 10101
Gamma-aminobutyric acid receptor subunit epsilon5005
Chain A, Ferritin light chain1001
Chain A, Cruzipain2002
thioredoxin reductase2002
ATAD5 protein, partial4004
aldehyde dehydrogenase 1 family, member A16006
Parkin2002
Caspase-71001
peripheral myelin protein 22 isoform 13003
vitamin D3 receptor isoform VDRA4004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
caspase-31001
serine/threonine-protein kinase mTOR isoform 11001
serine/threonine-protein kinase PLK11001
Ornithine decarboxylase0001
Adenosine receptor A30404
Retinoic acid receptor alpha0101
Alpha-1B adrenergic receptor0404
Alpha-2B adrenergic receptor0404
Retinoic acid receptor gamma0101
Retinoic acid receptor beta0101
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0101
Retinoic acid receptor RXR-beta0101
Retinoic acid receptor RXR-gamma0101
Cellular retinoic acid-binding protein 10101
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0404
Cellular retinoic acid-binding protein 10011
Mitogen-activated protein kinase 140101
Rap guanine nucleotide exchange factor 41001
Olfactory receptor 51E20101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
microphthalmia-associated transcription factor isoform 90101
caspase-1 isoform alpha precursor1001
Solute carrier organic anion transporter family member 2B1 0203
Tumor necrosis factor0101
Neuraminidase0101
Prostaglandin G/H synthase 10101
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0202
Platelet-activating factor receptor1001
Cystathionine gamma-lyase0101
Prostaglandin G/H synthase 20202
Histamine H2 receptor3003
Caspase-71001
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Protein-arginine deiminase type-40101
Cystine/glutamate transporter0101
Hydroxyacid oxidase 10101
large T antigen0101
PPM1D protein1001
nonstructural protein 12002
nuclear receptor subfamily 1, group I, member 25005
nuclear factor erythroid 2-related factor 2 isoform 26006
muscleblind-like protein 1 isoform 14004
Nuclear receptor subfamily 1 group I member 20022
Glucocorticoid receptor012320
Glycine receptor subunit alpha-1012012
Androgen receptor0505
Glycine receptor subunit beta012012
Glycine receptor subunit alpha-2012012
Glycine receptor subunit alpha-3012012
Nuclear receptor subfamily 1 group I member 20011
Glucose-6-phosphate 1-dehydrogenase0101
thyroid stimulating hormone receptor2002
Thioredoxin reductase 0101
lamin isoform A-delta104004
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
TAR DNA-binding protein 432002
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Lanosterol 14-alpha demethylase0202
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0303
Progesterone receptor0304
Glucocorticoid receptor0213
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0325
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0303
thioredoxin glutathione reductase2002
Nuclear receptor ROR-gamma1001
glp-1 receptor, partial2002
glucocerebrosidase1001
Interleukin-50101
Interleukin-50101
Matrix metalloproteinase-90101
Interleukin-5 receptor subunit alpha0101
Sodium-dependent serotonin transporter0101
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Insulin-degrading enzyme0101
Urease subunit alpha0101
D(3) dopamine receptor0202
Fatty acid synthase0202
WD repeat-containing protein 50101
Urease subunit beta0101
Histone-lysine N-methyltransferase 2A0101
NAD(+) hydrolase SARM10101
Cytosolic endo-beta-N-acetylglucosaminidase0101
Broad substrate specificity ATP-binding cassette transporter ABCG20202
interleukin 81001
DNA-directed RNA polymerase subunit beta0101
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Solute carrier organic anion transporter family member 1A40101
Albumin0011
NH(3)-dependent NAD(+) synthetase0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Cytochrome P450 2B60011
Arylacetamide deacetylase0102
Caspase-10101
Alpha-synuclein0101
Solute carrier organic anion transporter family member 1A10101
Solute carrier organic anion transporter family member 1A20101
Glutathione S-transferase omega-10101
DNA-directed RNA polymerase subunit beta0101
cystic fibrosis transmembrane conductance regulator0101
Aldo-keto reductase family 1 member B10202
Alpha-2A adrenergic receptor0202
Cytochrome P450 2D60101
Sodium-dependent noradrenaline transporter 0202
C-8 sterol isomerase0101
Squalene monooxygenase 0101
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Sigma non-opioid intracellular receptor 10202
MSH0001
pyruvate kinase1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a1001
polyunsaturated fatty acid lipoxygenase ALOX121001
atrial natriuretic peptide receptor 1 precursor1001
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
M-phase phosphoprotein 81001
pyruvate kinase PKM isoform b1001
neuropeptide S receptor isoform A1001
Hematopoietic prostaglandin D synthase0101
Transient receptor potential cation channel subfamily A member 10101
Integrin beta-31001
Integrin alpha-IIb1001
Ornithine decarboxylase1001
NACHT, LRR and PYD domains-containing protein 3 0101
Transient receptor potential cation channel subfamily V member 20101
Smad31001
procathepsin L isoform 1 preproprotein0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]