| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| IDH1 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| geminin | 7 | 0 | 0 | 7 |
| Sex hormone-binding globulin | 0 | 1 | 7 | 8 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| TDP1 protein | 7 | 0 | 0 | 7 |
| GLI family zinc finger 3 | 7 | 0 | 0 | 7 |
| AR protein | 8 | 0 | 0 | 8 |
| Smad3 | 2 | 0 | 0 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| estrogen receptor 2 (ER beta) | 5 | 0 | 0 | 5 |
| progesterone receptor | 5 | 0 | 0 | 5 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 4 | 0 | 0 | 4 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 8 | 0 | 0 | 8 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 7 | 0 | 0 | 7 |
| estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
| peroxisome proliferator-activated receptor delta | 6 | 0 | 0 | 6 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 5 | 0 | 0 | 5 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 6 | 0 | 0 | 6 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Beta-glucuronidase | 0 | 2 | 0 | 2 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Corticosteroid-binding globulin | 0 | 6 | 0 | 6 |
| Aromatase | 0 | 3 | 0 | 6 |
| Androgen receptor | 0 | 4 | 1 | 5 |
| Gastrin/cholecystokinin type B receptor | 0 | 0 | 0 | 1 |
| Testosterone 17-beta-dehydrogenase 3 | 0 | 3 | 0 | 3 |
| Alpha-synuclein | 1 | 1 | 0 | 2 |
| Nuclear receptor ROR-gamma | 4 | 0 | 0 | 4 |
| TAR DNA-binding protein 43 | 3 | 0 | 0 | 3 |
| Chain A, retinol dehydratase | 0 | 1 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 1 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 4 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 1 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 1 | 0 | 2 |
| Solute carrier organic anion transporter family member 1A1 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 1 | 0 | 2 |
| G-protein coupled bile acid receptor 1 | 0 | 0 | 4 | 4 |
| GABA theta subunit | 1 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 1 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| Beta-glucuronidase | 0 | 1 | 0 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
| NPC1-like intracellular cholesterol transporter 1 | 0 | 0 | 1 | 1 |
| Thymidine kinase 2 | 0 | 1 | 0 | 1 |
| Deoxycytidine kinase | 0 | 0 | 0 | 2 |
| Probable deoxycytidylate deaminase | 0 | 0 | 0 | 1 |
| Cytidine deaminase | 0 | 0 | 0 | 2 |
| AAA family ATPase | 0 | 0 | 0 | 2 |
| Reverse transcriptase/RNaseH | 0 | 0 | 1 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Chain A, Sex Hormone-Binding Globulin | 0 | 0 | 1 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| Plasma kallikrein | 0 | 1 | 0 | 1 |
| Glucocorticoid receptor | 0 | 1 | 0 | 2 |
| Progesterone receptor | 0 | 1 | 0 | 1 |
| Progesterone receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
| Sex hormone-binding globulin | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 2 | 2 | 6 |
| Androgen receptor | 0 | 1 | 1 | 2 |
| Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 0 | 1 | 1 |
| Cannabinoid receptor 2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor | 0 | 1 | 0 | 1 |
| Neuropeptide FF receptor 2 | 0 | 0 | 0 | 1 |
| ALK tyrosine kinase receptor | 0 | 1 | 0 | 1 |
| Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN) | 0 | 1 | 0 | 1 |
| Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN) | 0 | 1 | 0 | 1 |
| Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN) | 0 | 1 | 0 | 1 |
| Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN) | 0 | 1 | 0 | 1 |
| Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN) | 0 | 1 | 0 | 1 |
| Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN) | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 4 | 0 | 0 | 4 |
| ClpP | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 2 | 0 | 0 | 2 |
| Chain A, DEOXYNUCLEOSIDE KINASE | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Transmembrane protease serine 2 | 0 | 0 | 1 | 1 |
| Procathepsin L | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1a | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Spike glycoprotein | 0 | 0 | 1 | 1 |
| Equilibrative nucleoside transporter 1 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme 2 | 0 | 0 | 1 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Serum paraoxonase/arylesterase 1 | 0 | 2 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| Genome polyprotein | 0 | 1 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| Tyrosine-protein kinase ABL1 | 0 | 1 | 0 | 1 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Tubulin alpha-1A chain | 0 | 0 | 1 | 2 |
| Tubulin beta chain | 0 | 0 | 1 | 1 |
| Tubulin beta-4A chain | 0 | 1 | 1 | 3 |
| Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
| Integrin beta-3 | 0 | 1 | 0 | 1 |
| Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
| Integrin alpha-V | 0 | 1 | 0 | 1 |
| Tubulin beta chain | 0 | 1 | 1 | 3 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 3 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Tubulin alpha-3C chain | 0 | 1 | 1 | 3 |
| Botulinum neurotoxin type A | 0 | 1 | 0 | 1 |
| Apoptosis regulator Bcl-2 | 0 | 1 | 0 | 1 |
| 60 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Fibroblast growth factor receptor 1 | 0 | 1 | 0 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1-6 | 0 | 1 | 0 | 1 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A4 | 0 | 1 | 0 | 1 |
| Cholecystokinin receptor type A | 0 | 2 | 0 | 2 |
| Melanocortin receptor 5 | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 2B10 | 0 | 1 | 0 | 1 |
| Delta-type opioid receptor | 0 | 2 | 0 | 2 |
| 10 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Tubulin alpha-1B chain | 0 | 1 | 1 | 3 |
| Tubulin alpha-4A chain | 0 | 1 | 1 | 3 |
| Tubulin beta-4B chain | 0 | 1 | 1 | 3 |
| Bcl-2-like protein 1 | 0 | 1 | 0 | 1 |
| Tyrosine-protein kinase Mer | 0 | 1 | 0 | 1 |
| Tubulin beta-3 chain | 0 | 2 | 1 | 4 |
| Tubulin beta-2A chain | 0 | 1 | 1 | 3 |
| Thiosulfate sulfurtransferase | 0 | 1 | 0 | 1 |
| Beta-tubulin | 0 | 1 | 0 | 1 |
| Tubulin beta-8 chain | 0 | 1 | 1 | 3 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Tubulin beta-2B chain | 0 | 0 | 1 | 3 |
| Tubulin alpha-3E chain | 0 | 1 | 1 | 3 |
| Tubulin alpha-1A chain | 0 | 1 | 1 | 3 |
| 10 kDa chaperonin | 0 | 1 | 0 | 1 |
| Similar to alpha-tubulin isoform 1 | 0 | 0 | 1 | 3 |
| Similar to alpha-tubulin isoform 1 | 0 | 0 | 0 | 2 |
| Tubulin alpha-1C chain | 0 | 1 | 1 | 3 |
| Tubulin beta-6 chain | 0 | 1 | 1 | 3 |
| Tubulin beta-2B chain | 0 | 1 | 1 | 3 |
| Tubulin beta-1 chain | 0 | 1 | 1 | 3 |
| Nucleotide-binding oligomerization domain-containing protein 2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 2 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 2 | 0 | 2 |
| Lanosterol 14-alpha demethylase | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |