Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Protein farnesyltransferase subunit beta | 0 | 1 | 0 | 1 |
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | 0 | 1 | 0 | 1 |
RAR-related orphan receptor gamma | 5 | 0 | 0 | 5 |
SMAD family member 2 | 2 | 0 | 0 | 2 |
SMAD family member 3 | 2 | 0 | 0 | 2 |
GLI family zinc finger 3 | 6 | 0 | 0 | 6 |
AR protein | 7 | 0 | 0 | 7 |
nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
progesterone receptor | 4 | 0 | 0 | 4 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
retinoic acid nuclear receptor alpha variant 1 | 6 | 0 | 0 | 6 |
retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
estrogen-related nuclear receptor alpha | 4 | 0 | 0 | 4 |
pregnane X nuclear receptor | 6 | 0 | 0 | 6 |
estrogen nuclear receptor alpha | 7 | 0 | 0 | 7 |
G | 3 | 0 | 0 | 3 |
cytochrome P450 2D6 | 3 | 0 | 0 | 3 |
peroxisome proliferator activated receptor gamma | 2 | 0 | 0 | 2 |
aryl hydrocarbon receptor | 4 | 0 | 0 | 4 |
thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
Histone H2A.x | 2 | 0 | 0 | 2 |
thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
Interferon beta | 4 | 0 | 0 | 4 |
HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
Glutamate receptor 2 | 3 | 0 | 0 | 3 |
Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
Chain A, BCL-2-RELATED PROTEIN A1 | 0 | 0 | 1 | 1 |
Chain A, Cruzipain | 1 | 0 | 0 | 1 |
Luciferase | 1 | 0 | 0 | 1 |
acid sphingomyelinase | 1 | 0 | 0 | 1 |
interleukin 8 | 1 | 0 | 0 | 1 |
acetylcholinesterase | 1 | 0 | 0 | 1 |
PAX8 | 0 | 0 | 0 | 1 |
glp-1 receptor, partial | 2 | 0 | 0 | 2 |
15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
pregnane X receptor | 2 | 0 | 0 | 2 |
phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
USP1 protein, partial | 1 | 0 | 0 | 1 |
TDP1 protein | 4 | 0 | 0 | 4 |
caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
PINK1 | 1 | 0 | 0 | 1 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
67.9K protein | 1 | 0 | 0 | 1 |
glucocerebrosidase | 1 | 0 | 0 | 1 |
Parkin | 1 | 0 | 0 | 1 |
peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
heat shock protein 90 | 0 | 0 | 1 | 1 |
caspase-3 | 1 | 0 | 0 | 1 |
IDH1 | 2 | 0 | 0 | 2 |
euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
calcineurin A1, putative | 0 | 0 | 1 | 1 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
activating transcription factor 6 | 1 | 0 | 0 | 1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
hepatocyte nuclear factor 4-alpha isoform 2 | 0 | 1 | 0 | 1 |
cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
perilipin-5 | 0 | 1 | 0 | 1 |
thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
perilipin-1 | 0 | 1 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 3 |
potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
heat shock protein beta-1 | 2 | 0 | 0 | 2 |
huntingtin isoform 2 | 1 | 0 | 0 | 1 |
importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
ubiquitin-conjugating enzyme E2 N | 0 | 1 | 0 | 1 |
nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
flap endonuclease 1 | 1 | 0 | 0 | 1 |
protein AF-9 isoform a | 0 | 0 | 0 | 1 |
snurportin-1 | 1 | 0 | 0 | 1 |
melanocortin receptor 4 | 0 | 1 | 0 | 1 |
CAAX prenyl protease | 0 | 0 | 0 | 1 |
urokinase-type plasminogen activator precursor | 2 | 0 | 0 | 2 |
plasminogen precursor | 2 | 0 | 0 | 2 |
bcl-2-related protein A1 | 0 | 1 | 0 | 1 |
urokinase plasminogen activator surface receptor precursor | 2 | 0 | 0 | 2 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
geminin | 3 | 0 | 0 | 3 |
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | 0 | 1 | 0 | 1 |
DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
glycogen synthase kinase-3 alpha | 0 | 0 | 0 | 1 |
hexokinase HKDC1 | 0 | 1 | 0 | 1 |
DNA repair protein RAD52 homolog isoform a | 0 | 0 | 0 | 1 |
bcl-2-like protein 11 isoform 1 | 0 | 0 | 1 | 1 |
lethal factor (plasmid) | 1 | 0 | 0 | 1 |
lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
Synaptojanin-2 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 2 | 0 | 2 | 0 | 2 |
Solute carrier family 22 member 1 | 0 | 3 | 0 | 3 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
Synaptojanin-1 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 3 | 0 | 2 | 0 | 2 |
Glutathione reductase, mitochondrial | 0 | 1 | 0 | 2 |
Integrin beta-3 | 2 | 0 | 0 | 2 |
72 kDa type IV collagenase | 0 | 1 | 0 | 1 |
Integrin alpha-IIb | 2 | 0 | 0 | 2 |
Matrix metalloproteinase-9 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
Trypanothione reductase | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
Alpha-synuclein | 1 | 0 | 0 | 1 |
Histamine H2 receptor | 1 | 0 | 0 | 1 |
Spike glycoprotein | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase | 0 | 1 | 0 | 1 |
Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
GABA theta subunit | 2 | 0 | 0 | 2 |
Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
Ataxin-2 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
Spermine oxidase | 0 | 1 | 0 | 1 |
Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
thioredoxin reductase | 1 | 0 | 0 | 1 |
NFKB1 protein, partial | 1 | 0 | 0 | 1 |
GALC protein | 1 | 0 | 0 | 1 |
Thrombopoietin | 1 | 0 | 0 | 1 |
nonstructural protein 1 | 1 | 0 | 0 | 1 |
chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
Sex hormone-binding globulin | 0 | 0 | 1 | 1 |
Corticosteroid-binding globulin | 0 | 2 | 0 | 2 |
Mineralocorticoid receptor | 0 | 2 | 2 | 4 |
Androgen receptor | 0 | 2 | 0 | 2 |
C-8 sterol isomerase | 0 | 1 | 0 | 1 |
Solute carrier organic anion transporter family member 1A1 | 0 | 1 | 0 | 1 |
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 1 | 0 | 2 | 0 | 2 |
Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 2 | 0 | 2 | 0 | 2 |
EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
DNA polymerase beta | 1 | 0 | 0 | 1 |
ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
Bile salt export pump | 0 | 2 | 0 | 2 |
Histamine H2 receptor | 0 | 2 | 0 | 2 |
Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
Adenosine receptor A2a | 0 | 2 | 0 | 2 |
7,8-dihydro-8-oxoguanine triphosphatase | 0 | 1 | 0 | 1 |
Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
Toll-like receptor 8 | 0 | 0 | 1 | 1 |
Toll-like receptor 7 | 0 | 0 | 1 | 1 |
luciferase | 0 | 0 | 0 | 1 |
nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
Fatty acid-binding protein, liver | 0 | 1 | 0 | 1 |
Estrogen receptor | 0 | 2 | 0 | 2 |
Glucocorticoid receptor | 0 | 2 | 1 | 8 |
Progesterone receptor | 0 | 2 | 0 | 3 |
Glucocorticoid receptor | 0 | 1 | 1 | 2 |
Glucocorticoid receptor | 0 | 0 | 1 | 1 |
Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
Androgen receptor | 0 | 2 | 0 | 2 |
Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
Glutamine synthetase | 0 | 0 | 1 | 1 |
Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
Histamine H1 receptor | 0 | 0 | 1 | 1 |
Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
Nociceptin receptor | 0 | 0 | 1 | 1 |
Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
Estrogen receptor beta | 0 | 2 | 0 | 2 |
Chain A, CHORISMATE MUTASE | 0 | 1 | 0 | 1 |
Chain A, TYROSYL-tRNA SYNTHETASE | 0 | 0 | 1 | 1 |
Polyphenol oxidase 2 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 12 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 1 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 2 | 0 | 0 | 0 | 1 |
Plasma kallikrein | 0 | 0 | 0 | 1 |
Carbonic anhydrase 3 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 6 | 0 | 0 | 0 | 1 |
Adenosine receptor A1 | 0 | 0 | 0 | 1 |
Adenosine receptor A2a | 0 | 0 | 0 | 1 |
Carbonic anhydrase 5A, mitochondrial | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 1 | 0 | 0 | 0 | 1 |
Carbonic anhydrase | 0 | 0 | 0 | 1 |
Carbonic anhydrase 7 | 0 | 0 | 0 | 1 |
Carbonic anhydrase | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 0 | 1 |
Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
SLC16A10 protein | 0 | 0 | 0 | 1 |
Carbonic anhydrase 9 | 0 | 0 | 0 | 1 |
Carbonic anhydrase | 0 | 0 | 0 | 1 |
Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 1 |
Carbonic anhydrase | 0 | 0 | 0 | 1 |
Carbonic anhydrase | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 0 | 1 |
Carbonic anhydrase | 0 | 0 | 0 | 1 |
Tubulin--tyrosine ligase | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 0 | 1 |
Monocarboxylate transporter 10 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 15 | 0 | 0 | 0 | 1 |
Taste receptor type 2 member 14 | 0 | 0 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 0 | 1 |
Carbonic anhydrase 14 | 0 | 0 | 0 | 1 |
Carbonic anhydrase 5B, mitochondrial | 0 | 0 | 0 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |