Page last updated: 2024-09-27

Flaviviridae Infections

Infections with viruses of the family FLAVIVIRIDAE.

Synonyms(2)

Synonym
Infections, Flaviviridae
Flaviviridae Infections

Research

Studies (84)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's1 (1.19)12.5806
2000's55 (65.48)18.1394
2010's24 (28.57)28.8240
2020's4 (4.76)9.53
DrugIndicatedRelationship StrengthStudiesTrials
amantadine0low10
methadone0low10
sucrose0low10
ribavirin0medium41
lamivudine0low10
adenosine0low10
1,4-3,6-dianhydromannitol0low10
n-methyladenosine0low10
aflatoxin b10low10
ritonavir0medium11
tacrolimus0low10
xanthohumol0low10
clove0low20
sofosbuvir0low10

Protein Targets (300)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein5005
signal transducer and activator of transcription 6, interleukin-4 induced2002
regulator of G-protein signaling 42002
glucocorticoid receptor [Homo sapiens]3003
retinoid X nuclear receptor alpha2002
estrogen nuclear receptor alpha6006
NPYLR7B0011
arylsulfatase A3003
IDH11001
Histone H2A.x2002
glycogen synthase kinase-3 beta isoform 10022
mitogen-activated protein kinase 12002
flap endonuclease 11001
nuclear receptor ROR-gamma isoform 13003
peripheral myelin protein 224004
survival motor neuron protein isoform d2002
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit2002
Rap guanine nucleotide exchange factor 32002
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0101
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0224
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30427
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0224
Glutamate receptor 22002
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0003
Adenosine receptor A10112
Adenosine receptor A30202
Adenosine receptor A2a0226
Adenosine receptor A2b0013
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10428
Adenosine receptor A2a0112
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
Acetylcholinesterase0101
Acetylcholinesterase0101
acetylcholinesterase1001
thioredoxin reductase2002
RAR-related orphan receptor gamma2002
NFKB1 protein, partial1001
GLI family zinc finger 32002
thyroid stimulating hormone receptor2002
EWS/FLI fusion protein2002
putative alpha-glucosidase1001
euchromatic histone-lysine N-methyltransferase 22002
thyroid hormone receptor beta isoform 24004
heat shock protein beta-11001
histone acetyltransferase KAT2A isoform 12002
lamin isoform A-delta103003
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0102
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0101
Spike glycoprotein2013
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0101
Solute carrier family 22 member 10101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0101
Multidrug and toxin extrusion protein 10202
Solute carrier family 22 member 20101
Glutamate receptor ionotropic, NMDA 3A0101
ATP-dependent phosphofructokinase2002
Hsf1 protein0011
Microtubule-associated protein tau2002
ATP-binding cassette sub-family C member 30404
Multidrug resistance-associated protein 40404
Voltage-dependent L-type calcium channel subunit alpha-1F0303
Bile salt export pump0404
Albumin0013
Voltage-dependent L-type calcium channel subunit alpha-1D 0303
Capsid protein 0112
Voltage-dependent L-type calcium channel subunit alpha-1S0303
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Reverse transcriptase/RNaseH 0011
Canalicular multispecific organic anion transporter 10404
ATP-dependent translocase ABCB10202
D(2) dopamine receptor0101
Cytochrome P450 2B60101
D(4) dopamine receptor0101
Mu-type opioid receptor0404
D(3) dopamine receptor0101
Delta-type opioid receptor0101
Kappa-type opioid receptor0303
Potassium voltage-gated channel subfamily H member 20101
Mas-related G-protein coupled receptor member X20011
Aldehyde oxidase 1 0101
ATAD5 protein, partial1001
USP1 protein, partial2002
TDP1 protein4004
Smad31001
vasopressin V1b receptor1001
chromobox protein homolog 12002
transcriptional regulator ERG isoform 31001
relaxin receptor 1 isoform 11001
relaxin receptor 2 isoform 11001
Ataxin-24004
NS5 0022
interleukin 81001
Thrombopoietin1001
aldehyde dehydrogenase 1 family, member A12002
nuclear receptor subfamily 1, group I, member 31001
cytochrome P450 family 3 subfamily A polypeptide 42002
retinoic acid nuclear receptor alpha variant 11001
estrogen-related nuclear receptor alpha2002
farnesoid X nuclear receptor2002
pregnane X nuclear receptor3003
peroxisome proliferator activated receptor gamma3003
alpha-galactosidase2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
Spike glycoprotein0011
Replicase polyprotein 1ab0011
peripheral myelin protein 22 isoform 11001
nuclear factor erythroid 2-related factor 2 isoform 21001
nuclear factor erythroid 2-related factor 2 isoform 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
geminin2002
cytochrome P450 3A4 isoform 11001
muscarinic acetylcholine receptor M11001
Gamma-aminobutyric acid receptor subunit pi1001
Transmembrane protease serine 20011
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Cellular tumor antigen p533003
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Nuclear receptor ROR-gamma1001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Adenosine receptor A10101
Genome polyprotein0011
GABA theta subunit1001
Angiotensin-converting enzyme 2 0011
Gamma-aminobutyric acid receptor subunit epsilon1001
Chain A, HIV-1 PROTEASE0101
Chain B, HIV-1 PROTEASE0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, POL polyprotein0101
Chain B, POL polyprotein0101
Chain A, Beta-lactamase1001
Chain A, Ferritin light chain2002
Chain A, Cruzipain1001
Chain A, Endothiapepsin0101
Chain A, Endothiapepsin0101
Luciferase1001
SMAD family member 21001
Fumarate hydratase1001
GLS protein1001
SMAD family member 31001
estrogen receptor 2 (ER beta)1001
progesterone receptor1001
G1001
cytochrome P450 2D61001
polyprotein1001
peroxisome proliferator-activated receptor delta1001
aryl hydrocarbon receptor1001
activating transcription factor 61001
vitamin D3 receptor isoform VDRA1001
DNA polymerase kappa isoform 12002
neuropeptide S receptor isoform A1001
Nuclear receptor subfamily 1 group I member 20022
Solute carrier family 22 member 30101
Solute carrier organic anion transporter family member 2B1 0202
Interferon beta1001
HLA class I histocompatibility antigen, B alpha chain 1001
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Gag-Pol polyprotein0101
Cytochrome P450 1A20202
Gag-Pol polyprotein0101
ATP-dependent translocase ABCB10101
Cytochrome P450 3A40405
Cytochrome P450 2D60202
Cytochrome P450 2C9 0213
Gag-Pol polyprotein0101
Alpha-1B adrenergic receptor0101
Cytochrome P450 3A50202
ATP-dependent translocase ABCB10101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Alpha-1D adrenergic receptor0101
Thromboxane-A synthase 0101
Gag-Pol polyprotein0101
Cytochrome P450 2C190101
Vasopressin V1a receptor0202
Alpha-1A adrenergic receptor0101
Thromboxane-A synthase0001
Sodium/bile acid cotransporter0101
Protease 0114
Multidrug and toxin extrusion protein 20101
Plasmepsin V 0101
Inositol hexakisphosphate kinase 11001
ATPase family AAA domain-containing protein 52002
Solute carrier organic anion transporter family member 1B30202
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Solute carrier organic anion transporter family member 1B10303
Protease 0213
cytochrome P450 2C9, partial1001
Cereblon isoform 40101
RNA-directed RNA polymerase 0012
Protein cereblon0101
Chain A, MALTOPORIN0011
Chain B, MALTOPORIN0011
Carbonic anhydrase 20112
Carbonic anhydrase 90112
UDP-glucuronosyltransferase 2B70001
UDP-glucuronosyltransferase 1A40001
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
3-phosphoinositide-dependent protein kinase 10101
Transthyretin0011
Polyunsaturated fatty acid 5-lipoxygenase0101
Protein kinase C alpha type0101
Nuclear factor NF-kappa-B p105 subunit0101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
Protein kinase C theta type0101
Thioredoxin reductase 1, cytoplasmic0101
NAD(P)H dehydrogenase [quinone] 10001
Thioredoxin reductase 30101
Thioredoxin reductase 2, mitochondrial0101
Lymphocyte antigen 960011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]