Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
Chain A, Membrane lipoprotein tmpC | 0 | 0 | 1 | 1 |
Chain A, Structure of PAE2307 in complex with adenosine | 0 | 0 | 1 | 1 |
Chain B, Structure of PAE2307 in complex with adenosine | 0 | 0 | 1 | 1 |
Chain A, ADENOSINE RECEPTOR A2A | 0 | 1 | 0 | 1 |
Chain A, ADENOSINE RECEPTOR A2A | 0 | 1 | 0 | 1 |
Chain A, tRNA (guanine-N(1)-)-methyltransferase | 0 | 0 | 1 | 1 |
Chain A, Uncharacterized protein MJ0883 | 0 | 0 | 1 | 1 |
AR protein | 5 | 0 | 0 | 5 |
signal transducer and activator of transcription 6, interleukin-4 induced | 2 | 0 | 0 | 2 |
regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
retinoid X nuclear receptor alpha | 2 | 0 | 0 | 2 |
estrogen nuclear receptor alpha | 6 | 0 | 0 | 6 |
NPYLR7B | 0 | 0 | 1 | 1 |
arylsulfatase A | 3 | 0 | 0 | 3 |
IDH1 | 1 | 0 | 0 | 1 |
Histone H2A.x | 2 | 0 | 0 | 2 |
glycogen synthase kinase-3 beta isoform 1 | 0 | 0 | 2 | 2 |
mitogen-activated protein kinase 1 | 2 | 0 | 0 | 2 |
flap endonuclease 1 | 1 | 0 | 0 | 1 |
nuclear receptor ROR-gamma isoform 1 | 3 | 0 | 0 | 3 |
peripheral myelin protein 22 | 4 | 0 | 0 | 4 |
survival motor neuron protein isoform d | 2 | 0 | 0 | 2 |
high affinity choline transporter 1 isoform a | 0 | 1 | 0 | 1 |
Sodium/nucleoside cotransporter 1 | 0 | 2 | 0 | 2 |
Calcium dependent protein kinase | 0 | 1 | 0 | 1 |
Mitogen-activated protein kinase kinase kinase 7 | 0 | 0 | 1 | 1 |
Sodium/nucleoside cotransporter 2 | 0 | 2 | 0 | 2 |
Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
Rap guanine nucleotide exchange factor 3 | 2 | 0 | 0 | 2 |
Purine nucleoside phosphorylase | 0 | 1 | 0 | 1 |
Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
Phosphoglycerate kinase 1 | 0 | 1 | 0 | 1 |
Adenosine deaminase | 0 | 0 | 0 | 1 |
Avidin | 0 | 0 | 1 | 1 |
Adenosine deaminase | 0 | 0 | 0 | 1 |
Glyceraldehyde-3-phosphate dehydrogenase | 0 | 2 | 0 | 2 |
Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
Insulin receptor | 0 | 0 | 0 | 1 |
Phosphoglycerate kinase 2 | 0 | 1 | 0 | 1 |
Heat shock protein HSP 90-alpha | 0 | 2 | 2 | 4 |
Platelet-derived growth factor receptor beta | 0 | 0 | 0 | 1 |
Adenosine receptor A3 | 0 | 4 | 2 | 7 |
Heat shock 70 kDa protein 1A | 0 | 1 | 0 | 1 |
Heat shock cognate 71 kDa protein | 0 | 0 | 1 | 1 |
Fibroblast growth factor receptor 1 | 0 | 0 | 0 | 1 |
Inosine-5'-monophosphate dehydrogenase 2 | 0 | 1 | 0 | 1 |
Endoplasmin | 0 | 2 | 2 | 4 |
Glutamate receptor 2 | 2 | 0 | 0 | 2 |
Inosine-5'-monophosphate dehydrogenase 1 | 0 | 1 | 0 | 1 |
Fibroblast growth factor receptor 2 | 0 | 0 | 0 | 1 |
Fibroblast growth factor receptor 4 | 0 | 0 | 0 | 1 |
Fibroblast growth factor receptor 3 | 0 | 0 | 0 | 1 |
Streptavidin | 0 | 0 | 1 | 1 |
Adenosylhomocysteinase | 0 | 0 | 0 | 3 |
Adenosine receptor A1 | 0 | 1 | 1 | 2 |
Adenosine receptor A3 | 0 | 2 | 0 | 2 |
Adenosine receptor A2a | 0 | 2 | 2 | 6 |
Adenosine receptor A2b | 0 | 0 | 1 | 3 |
Adenosine receptor A2b | 0 | 1 | 1 | 2 |
Adenylate kinase 2, mitochondrial | 0 | 1 | 0 | 1 |
Adenosine receptor A1 | 0 | 4 | 2 | 8 |
Adenosine receptor A2a | 0 | 1 | 1 | 2 |
Adenylate kinase isoenzyme 1 | 0 | 1 | 0 | 1 |
Phosphatidylinositol 4-kinase alpha | 0 | 2 | 0 | 3 |
Adenosine receptor A1 | 0 | 0 | 1 | 1 |
Adenosine kinase | 0 | 0 | 0 | 1 |
Adenosine deaminase | 0 | 0 | 0 | 1 |
Equilibrative nucleoside transporter 2 | 0 | 2 | 0 | 2 |
Phosphatidylinositol 4-kinase type 2-beta | 0 | 2 | 0 | 3 |
Histone-lysine N-methyltransferase, H3 lysine-79 specific | 0 | 1 | 0 | 1 |
Equilibrative nucleoside transporter 1 | 0 | 2 | 0 | 2 |
Phosphatidylinositol 4-kinase type 2-alpha | 0 | 2 | 0 | 3 |
Solute carrier family 28 member 3 | 0 | 2 | 0 | 2 |
Adenosine kinase | 0 | 1 | 0 | 2 |
Phosphatidylinositol 4-kinase beta | 0 | 2 | 0 | 3 |
5-methylthioadenosine/S-adenosylhomocysteine deaminase | 0 | 0 | 0 | 1 |
Adenosine transporter 1 | 0 | 0 | 0 | 1 |
Acetylcholinesterase | 0 | 1 | 0 | 1 |
Acetylcholinesterase | 0 | 1 | 0 | 1 |
acetylcholinesterase | 1 | 0 | 0 | 1 |
thioredoxin reductase | 2 | 0 | 0 | 2 |
RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
NFKB1 protein, partial | 1 | 0 | 0 | 1 |
GLI family zinc finger 3 | 2 | 0 | 0 | 2 |
thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
putative alpha-glucosidase | 1 | 0 | 0 | 1 |
euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
heat shock protein beta-1 | 1 | 0 | 0 | 1 |
histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
Solute carrier family 22 member 2 | 0 | 2 | 0 | 3 |
Solute carrier family 22 member 1 | 0 | 1 | 0 | 2 |
Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
Matrix protein 2 | 0 | 1 | 1 | 2 |
Matrix protein 2 | 0 | 1 | 2 | 3 |
Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
Spike glycoprotein | 2 | 0 | 1 | 3 |
Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
Multidrug and toxin extrusion protein 1 | 0 | 2 | 0 | 2 |
Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
Hsf1 protein | 0 | 0 | 1 | 1 |
Microtubule-associated protein tau | 2 | 0 | 0 | 2 |
ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 3 | 0 | 3 |
Bile salt export pump | 0 | 4 | 0 | 4 |
Albumin | 0 | 0 | 1 | 3 |
Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 3 | 0 | 3 |
Capsid protein | 0 | 1 | 1 | 2 |
Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 3 | 0 | 3 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 3 | 0 | 3 |
Reverse transcriptase/RNaseH | 0 | 0 | 1 | 1 |
Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
ATP-dependent translocase ABCB1 | 0 | 2 | 0 | 2 |
D(2) dopamine receptor | 0 | 1 | 0 | 1 |
Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
D(4) dopamine receptor | 0 | 1 | 0 | 1 |
Mu-type opioid receptor | 0 | 4 | 0 | 4 |
D(3) dopamine receptor | 0 | 1 | 0 | 1 |
Delta-type opioid receptor | 0 | 1 | 0 | 1 |
Kappa-type opioid receptor | 0 | 3 | 0 | 3 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
Mas-related G-protein coupled receptor member X2 | 0 | 0 | 1 | 1 |
Aldehyde oxidase 1 | 0 | 1 | 0 | 1 |
ATAD5 protein, partial | 1 | 0 | 0 | 1 |
USP1 protein, partial | 2 | 0 | 0 | 2 |
TDP1 protein | 4 | 0 | 0 | 4 |
Smad3 | 1 | 0 | 0 | 1 |
vasopressin V1b receptor | 1 | 0 | 0 | 1 |
chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
relaxin receptor 1 isoform 1 | 1 | 0 | 0 | 1 |
relaxin receptor 2 isoform 1 | 1 | 0 | 0 | 1 |
Ataxin-2 | 4 | 0 | 0 | 4 |
NS5 | 0 | 0 | 2 | 2 |
interleukin 8 | 1 | 0 | 0 | 1 |
Thrombopoietin | 1 | 0 | 0 | 1 |
aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
alpha-galactosidase | 2 | 0 | 0 | 2 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
Spike glycoprotein | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 2 | 0 | 0 | 2 |
urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
plasminogen precursor | 1 | 0 | 0 | 1 |
urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
geminin | 2 | 0 | 0 | 2 |
cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
Transmembrane protease serine 2 | 0 | 0 | 1 | 1 |
Polymerase basic protein 2 | 0 | 0 | 1 | 1 |
RNA-directed RNA polymerase catalytic subunit | 0 | 0 | 1 | 1 |
Polymerase acidic protein | 0 | 0 | 1 | 1 |
Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
Procathepsin L | 0 | 0 | 1 | 1 |
Replicase polyprotein 1a | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
Adenosine receptor A1 | 0 | 1 | 0 | 1 |
Genome polyprotein | 0 | 0 | 1 | 1 |
GABA theta subunit | 1 | 0 | 0 | 1 |
Angiotensin-converting enzyme 2 | 0 | 0 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
Chain A, HIV-1 PROTEASE | 0 | 1 | 0 | 1 |
Chain B, HIV-1 PROTEASE | 0 | 1 | 0 | 1 |
Chain A, POL polyprotein | 0 | 1 | 0 | 1 |
Chain B, POL polyprotein | 0 | 1 | 0 | 1 |
Chain A, POL polyprotein | 0 | 1 | 0 | 1 |
Chain B, POL polyprotein | 0 | 1 | 0 | 1 |
Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
Chain A, Cruzipain | 1 | 0 | 0 | 1 |
Chain A, Endothiapepsin | 0 | 1 | 0 | 1 |
Chain A, Endothiapepsin | 0 | 1 | 0 | 1 |
Luciferase | 1 | 0 | 0 | 1 |
SMAD family member 2 | 1 | 0 | 0 | 1 |
Fumarate hydratase | 1 | 0 | 0 | 1 |
GLS protein | 1 | 0 | 0 | 1 |
SMAD family member 3 | 1 | 0 | 0 | 1 |
estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
progesterone receptor | 1 | 0 | 0 | 1 |
G | 1 | 0 | 0 | 1 |
cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
polyprotein | 1 | 0 | 0 | 1 |
peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
activating transcription factor 6 | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 2 | 2 |
Solute carrier family 22 member 3 | 0 | 1 | 0 | 1 |
Solute carrier organic anion transporter family member 2B1 | 0 | 2 | 0 | 2 |
Interferon beta | 1 | 0 | 0 | 1 |
HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
Cytochrome P450 1A2 | 0 | 2 | 0 | 2 |
Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Cytochrome P450 3A4 | 0 | 4 | 0 | 5 |
Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
Cytochrome P450 2C9 | 0 | 2 | 1 | 3 |
Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
Cytochrome P450 3A5 | 0 | 2 | 0 | 2 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Substance-K receptor | 0 | 2 | 0 | 2 |
UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 1 |
Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
Thromboxane-A synthase | 0 | 1 | 0 | 1 |
Gag-Pol polyprotein | 0 | 1 | 0 | 1 |
Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
Vasopressin V1a receptor | 0 | 2 | 0 | 2 |
Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
Thromboxane-A synthase | 0 | 0 | 0 | 1 |
Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
Protease | 0 | 1 | 1 | 4 |
Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
Plasmepsin V | 0 | 1 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
Solute carrier organic anion transporter family member 1B3 | 0 | 2 | 0 | 2 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 2 | 0 | 2 |
Solute carrier organic anion transporter family member 1B1 | 0 | 3 | 0 | 3 |
Protease | 0 | 2 | 1 | 3 |
cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
Cereblon isoform 4 | 0 | 1 | 0 | 1 |
RNA-directed RNA polymerase | 0 | 0 | 1 | 2 |
Protein cereblon | 0 | 1 | 0 | 1 |
Chain A, MALTOPORIN | 0 | 0 | 1 | 1 |
Chain B, MALTOPORIN | 0 | 0 | 1 | 1 |
Carbonic anhydrase 2 | 0 | 1 | 1 | 2 |
Carbonic anhydrase 9 | 0 | 1 | 1 | 2 |
UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 1 |
UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
Serine/threonine-protein kinase mTOR | 0 | 1 | 0 | 1 |
Peptidyl-prolyl cis-trans isomerase FKBP1A | 0 | 2 | 1 | 3 |
Peptidyl-prolyl cis-trans isomerase FKBP1B | 0 | 0 | 1 | 1 |
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 0 | 1 | 0 | 1 |
Peptidyl-prolyl cis-trans isomerase FKBP5 | 0 | 1 | 0 | 1 |
Splicing factor 3B subunit 3 | 0 | 1 | 0 | 1 |
3-phosphoinositide-dependent protein kinase 1 | 0 | 1 | 0 | 1 |
Transthyretin | 0 | 0 | 1 | 1 |
Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 1 |
Protein kinase C alpha type | 0 | 1 | 0 | 1 |
Nuclear factor NF-kappa-B p105 subunit | 0 | 1 | 0 | 1 |
Nuclear factor NF-kappa-B p100 subunit | 0 | 1 | 0 | 1 |
Transcription factor p65 | 0 | 1 | 0 | 1 |
Protein kinase C theta type | 0 | 1 | 0 | 1 |
Thioredoxin reductase 1, cytoplasmic | 0 | 1 | 0 | 1 |
NAD(P)H dehydrogenase [quinone] 1 | 0 | 0 | 0 | 1 |
Thioredoxin reductase 3 | 0 | 1 | 0 | 1 |
Thioredoxin reductase 2, mitochondrial | 0 | 1 | 0 | 1 |
Lymphocyte antigen 96 | 0 | 0 | 1 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |