| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| potassium voltage-gated channel subfamily H member 2 isoform d | 3 | 0 | 0 | 3 |
| thyroid hormone receptor beta isoform 2 | 10 | 0 | 0 | 10 |
| Solute carrier family 22 member 6 | 0 | 0 | 0 | 2 |
| Phosphoribosyl pyrophosphate synthase-associated protein 2 | 0 | 1 | 0 | 2 |
| Adenylate kinase isoenzyme 1 | 0 | 0 | 0 | 2 |
| Adenylate kinase 2, mitochondrial | 0 | 0 | 0 | 2 |
| Adenosine deaminase | 0 | 1 | 0 | 2 |
| Capsid protein | 0 | 0 | 2 | 2 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 4 |
| Solute carrier family 22 member 8 | 0 | 0 | 0 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, MTA/SAH nucleosidase | 0 | 1 | 0 | 1 |
| Chain A, Ribosome-inactivating protein alpha-trichosanthin | 0 | 0 | 1 | 1 |
| Chain A, Ricin A chain | 0 | 0 | 1 | 1 |
| Chain A, Ribosome-inactivating protein 3 | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| Chain A, Phenylethanolamine N-methyltransferase | 0 | 0 | 1 | 1 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| TDP1 protein | 7 | 0 | 0 | 7 |
| AR protein | 10 | 0 | 0 | 10 |
| nuclear receptor subfamily 1, group I, member 3 | 7 | 0 | 0 | 7 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 4 | 0 | 0 | 4 |
| glucocorticoid receptor [Homo sapiens] | 8 | 0 | 0 | 8 |
| estrogen-related nuclear receptor alpha | 10 | 0 | 0 | 10 |
| pregnane X nuclear receptor | 9 | 0 | 0 | 9 |
| estrogen nuclear receptor alpha | 12 | 0 | 0 | 12 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 6 | 0 | 0 | 6 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 3 | 0 | 0 | 3 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| tumor susceptibility gene 101 protein | 1 | 0 | 0 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| Voltage-dependent calcium channel gamma-2 subunit | 4 | 0 | 0 | 4 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Cyclin-dependent kinase 1 | 0 | 1 | 0 | 1 |
| Heat shock protein HSP 90-beta | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 4 | 0 | 0 | 4 |
| Xanthine dehydrogenase/oxidase | 0 | 3 | 0 | 3 |
| TAR DNA-binding protein 43 | 3 | 0 | 0 | 3 |
| Protein mono-ADP-ribosyltransferase PARP15 | 0 | 1 | 0 | 1 |
| Leucine-rich repeat serine/threonine-protein kinase 2 | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 4 | 0 | 0 | 4 |
| Ataxin-2 | 4 | 0 | 0 | 4 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 7 | 0 | 0 | 7 |
| progesterone receptor | 8 | 0 | 0 | 8 |
| IDH1 | 3 | 0 | 0 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 9 | 0 | 0 | 9 |
| geminin | 5 | 0 | 0 | 5 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| Polyphenol oxidase 2 | 0 | 1 | 0 | 1 |
| Hypoxanthine-guanine phosphoribosyltransferase | 0 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 1 | 2 |
| Nuclear receptor ROR-gamma | 0 | 1 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 2 | 1 | 4 |
| Purine nucleoside phosphorylase | 0 | 0 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| Shiga toxin subunit A | 0 | 1 | 0 | 1 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 3 | 0 | 0 | 3 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| Fumarate hydratase | 2 | 0 | 0 | 2 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| PPM1D protein | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 8 | 0 | 0 | 8 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 4 | 0 | 0 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | 8 | 0 | 0 | 8 |
| retinoid X nuclear receptor alpha | 9 | 0 | 0 | 9 |
| farnesoid X nuclear receptor | 5 | 0 | 0 | 5 |
| polyprotein | 2 | 0 | 0 | 2 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| Parkin | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 5 | 0 | 0 | 5 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| activating transcription factor 6 | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| hemoglobin subunit beta | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 2 | 0 | 0 | 2 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Interferon beta | 3 | 0 | 0 | 3 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Adenosine receptor A3 | 0 | 1 | 0 | 1 |
| DNA (cytosine-5)-methyltransferase 1 | 0 | 2 | 0 | 2 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
| Spike glycoprotein | 4 | 0 | 1 | 5 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Histone-lysine N-methyltransferase EHMT2 | 0 | 2 | 0 | 2 |
| ATP-dependent phosphofructokinase | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
| exodeoxyribonuclease V subunit RecD | 0 | 1 | 0 | 1 |
| exodeoxyribonuclease V subunit RecB | 0 | 1 | 0 | 1 |
| exodeoxyribonuclease V subunit RecC | 0 | 1 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| Sex hormone-binding globulin | 0 | 0 | 1 | 1 |
| Beta-glucuronidase | 0 | 1 | 0 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Beta-glucuronidase | 0 | 1 | 0 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 2 | 0 | 2 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| G-protein coupled bile acid receptor 1 | 0 | 0 | 1 | 1 |
| Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
| NPC1-like intracellular cholesterol transporter 1 | 0 | 0 | 1 | 1 |
| Thymidine kinase 2 | 0 | 1 | 0 | 1 |
| Deoxycytidine kinase | 0 | 0 | 0 | 2 |
| Probable deoxycytidylate deaminase | 0 | 0 | 0 | 1 |
| Cytidine deaminase | 0 | 0 | 0 | 2 |
| AAA family ATPase | 0 | 0 | 0 | 2 |
| Reverse transcriptase/RNaseH | 0 | 2 | 4 | 11 |
| Luciferase | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| Chain A, DEOXYNUCLEOSIDE KINASE | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Transmembrane protease serine 2 | 0 | 0 | 1 | 1 |
| Procathepsin L | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1a | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Equilibrative nucleoside transporter 1 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme 2 | 0 | 0 | 1 | 1 |
| Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | 0 | 0 | 1 | 1 |
| GALC protein | 1 | 0 | 0 | 1 |
| G | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Cytochrome P450 144 | 0 | 0 | 1 | 1 |
| Steroid C26-monooxygenase | 0 | 0 | 1 | 1 |
| Steroid C26-monooxygenase | 0 | 0 | 1 | 1 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Glucocorticoid receptor | 0 | 4 | 1 | 5 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| Translocator protein | 0 | 1 | 0 | 1 |
| Integrase | 0 | 1 | 0 | 1 |
| Cytochrome P450 14alpha-demethylase | 0 | 0 | 1 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Sterol 14-alpha demethylase | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Carnitine O-palmitoyltransferase 1, muscle isoform | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| pyruvate kinase PKM isoform a | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| tyrosine-protein kinase Yes | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | 0 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Thymidine kinase, cytosolic | 0 | 2 | 0 | 3 |
| Protein kinase C beta type | 0 | 1 | 0 | 1 |
| DNA polymerase beta | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 1 |
| Thymidine kinase, cytosolic | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A3 | 0 | 0 | 0 | 1 |
| Thymidylate kinase | 0 | 1 | 0 | 1 |
| Protein kinase C epsilon type | 0 | 1 | 0 | 1 |
| Thymidine kinase | 0 | 1 | 0 | 2 |
| Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
| Protease | 0 | 1 | 1 | 2 |
| Solute carrier family 22 member 11 | 0 | 0 | 0 | 1 |
| Thymidine kinase | 0 | 1 | 0 | 2 |
| Solute carrier family 22 member 7 | 0 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |