An inherited renal disorder characterized by defective NaCl reabsorption in the convoluted DISTAL KIDNEY TUBULE leading to HYPOKALEMIA. In contrast with BARTTER SYNDROME, Gitelman syndrome includes hypomagnesemia and normocalcemic hypocalciuria, and is caused by mutations in the thiazide-sensitive SODIUM-POTASSIUM-CHLORIDE SYMPORTERS.
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| "Bartter's and Gitelman's syndrome are two ends of a spectrum of inherited renal tubular disorders that present with hypokalemic metabolic alkalosis of varying severity." | ( Jha, R; Kumar, PJ; Modi, KD; Muthukrishnan, J, 2009) |
| "Gitelman's syndrome is a rare autosomal recessive syndrome presenting with hypocalciuria, hypomagnesiemia and hypokalemic metabolic alkalosis." | ( Christiansen, P; Hvelplund, C; Jeppesen, EM; Mortensen, HB, 2009) |
| "Gitelman syndrome is a primary tubular disorder causing hypokalaemic metabolic alkalosis with hypocalciuria." | ( Alvarez, V; Coto, E; Espinosa, L; Gil-Calvo, M; Gil-Peña, H; Herrero-Morín, JD; Loris, C; Rodríguez, J; Santos, F, 2011) |
| "Gitelman's syndrome is a primary renal tubular hypokalemic metabolic alkalosis." | ( Aladag, NB; Cakal, S; Karakoyun, S; Sahin, A; Yildiz, BS; Yildiz, M, 2013) |
| "Gitelman's syndrome is a congenital renal tubular defect which affects the apical membrane of the distal convoluted tubule of the renal system." | ( Gillham, J; Mathen, S; Venning, M, 2013) |
| "Gitelman syndrome is an inherited tubulopathy that must be considered in some settings of hypokalaemia." | ( Costa, F; Cotovio, P; Oliveira, N; Silva, C, 2013) |
| "Gitelman syndrome is a rare autosomal recessive inherited disease that affects the thiazide-sensitive sodium chloride cotransport channels and the magnesium channels of the distal renal tubuli." | ( Koch, C; Lichtenstern, C; Rickert, M; Schaumberg, S; Schneck, E, 2013) |
| "Gitelman's syndrome is a renal tubule disease of recessive autosomal inheritance in which the fundamental alteration is found in the distal tubule, specifically at the level of the Na/Cl cotransporter, is sensitive to thiazides, and coded in chromosome 16q." | ( Garcia-Esteve, L; Lafarga-Giribets, MA; Martín-Miguel, V; Rodrigo-Claverol, MD, 2014) |
| "Gitelman's syndrome is a rare autosomal recessive tubulopathy caused by a defect of the thiazide-sensitive sodium chloride co-transporter at the distal tubule, leading to hypokalemia, metabolic alkalosis, hypomagnesemia, hypocalciuria and low-to-normal blood pressure." | ( Dimitrijevic, Z; Mitic, B; Nikolic, V; Salinger-Martinovic, S, 2015) |
| "Gitelman syndrome is an autosomal recessive distal renal tubular disorder caused by defective sodium chloride transporters." | ( Koudsi, L; Mishra, V; Nikolova, S, 2016) |
| "Gitelman's syndrome is a rare autosomal-recessive tubular disorder characterized by hypomagnesemia and hypocalciuria associated to hypokalemia." | ( Bassetti, M; De Vita, S; Della Siega, P; Picco, L; Quartuccio, L; Zabotti, A, 2016) |
| "Bartter and Gitelman syndromes are typical normotensive salt losing hypokalaemic tubulopathies." | ( Alfandary, H; Landau, D, 2017) |
| "Gitelman syndrome is the most common inherited tubular disease resulting from mutations of the SLC12A3 gene that encodes the thiazide-sensitive sodium-chloride cotransporter in the early distal convoluted tubules." | ( Elisaf, MS; Filippatos, TD; Rizos, CV; Tzavella, E, 2018) |
| "Gitelman syndrome is a rare hereditary renal tubulopathy, responsable of hypokalemia and hypomagnesaemia-related ionic disorders, which management is poorly codified during pregnancy." | ( Blanchier, D; Elbouajaji, K; Pourrat, O; Sarreau, M, 2018) |
| "Gitelman syndrome is a rare pathology where there is a lack of homogeneity in management of pregnancy." | ( Blanchier, D; Elbouajaji, K; Pourrat, O; Sarreau, M, 2018) |
| "Gitelman syndrome is the most common renal tubulopathy, recently exhibiting a dramatic rise of incidence in Asia." | ( Achappa, B; Chauhan, N; Gopinath, B, 2019) |
| "Gitelman syndrome is an inherited tubulopathy characterized by renal salt wasting from the distal convoluted tubule." | ( Sayer, JA; Urwin, S; Willows, J, 2020) |
| "Bartter and Gitelman syndromes are rare inherited tubulopathies characterized by hypokalaemic, hypochloraemic metabolic alkalosis." | ( Besouw, MTP; Bockenhauer, D; Kleta, R, 2020) |
| "Gitelman syndrome is one of the salt losing tubulopathies." | ( Odstrcil-Bobillo, MS; Russo, PM; Ungaro, CM, 2020) |
| "Gitelman syndrome is a rare salt-losing renal tubular disorder associated with mutation of SLC12A3 gene, which encodes the Na-Cl co-transporter (NCCT)." | ( Chen, Y; Dong, B; Liu, X; Sun, X; Wang, F; Wang, Y; Zhao, W; Zhao, Y, 2020) |
| "Gitelman syndrome is an autosomal recessive renal tubulopathy." | ( Fujimoto, K; Mitamura, K; Nishiyama, Y; Norikane, T; Takami, Y; Yamamoto, Y, 2021) |
| "Gitelman syndrome is a rare inherited renal tubulopathy characterized by hypokalemia, hypomagnesemia and metabolic alcalosis." | ( Benner, A; Rombach, S; Schick, MA, 2021) |
| "Acquired Gitelman syndrome is a very rare disorder reported in association with autoimmune disorders, mostly Sjögren syndrome." | ( Gunapala, A; Perera, S; Ranaweerage, R, 2021) |
| "Gitelman syndrome is a recessive salt-wasting disorder characterized by hypomagnesemia, hypokalemia, metabolic alkalosis and hypocalciuria." | ( de Baaij, JHF; Schlingmann, KP, 2022) |