Page last updated: 2024-09-28

Extra-Mammary Paget Disease

Synonyms(8)

Synonym
Extramammary Paget's Disease
Extramammary Paget Disease
Paget's Disease, Extra-Mammary
Paget's Disease, Extramammary
Extra-Mammary Paget's Disease
Extra-Mammary Paget Disease
Paget Disease Extramammary
Paget Disease, Extra-Mammary

Research Excerpts

Overview

ExcerptReference
"A case of extramammary Paget's disease is reported."( Athar, M; Balducci, L; Crawford, ED; Khansur, T; McKenzie, D; Smith, GF, 1988)
"Advanced extramammary Paget's disease is also an adenocarcinoma of the skin."( Yamazaki, N, 1993)
"Advanced extramammary Paget's disease is also adenocarcinoma of the skin."( Yamazaki, N, 1997)
"Primary extramammary Paget's disease is thought to be an intraepidermal carcinoma indicating apocrine secretory differentiation."( Ohnishi, T; Watanabe, S, 2001)
"Extramammary Paget disease is an uncommon cutaneous neoplasm that presents as erythematous plaques most frequently located in the anogenital region."( Cohen, PR; Hetherington, GW; Nelson, BR; Schulze, KE; Tschen, JA, 2006)
"Extramammary Paget disease is a rare cutaneous neoplasm that most frequently affects the vulva."( Badiglian-Filho, L; Baiocchi, G; Begnami, MD; Costa, FD; Faloppa, CC; Fukazawa, EM; Kumagai, LY; Oliveira, RA; Soares, FA; Surima, WS, 2012)
"Extramammary Paget disease is a rare disease."( Evangelia Iavazzo, P; Gkegkes, ID; Iavazzo, C; Karachalios, C; Ntziora, F, 2014)
"Extramammary Paget's disease is a malignant intraepithelial carcinoma, which constitutes less than 1 % of all vulvar malignancies."( Isogai, N; Iwasa, T; Nakagawa, K; Nishio, K; Sakai, K; Shimizu, T; Takahama, T; Takeda, M; Tanizaki, J; Tsurutani, J; Wada, Y; Watanabe, S, 2016)
"Extramammary Paget's disease is a rare condition, and the vulva is a common site for it to occur."( Hutson, R; Nama, V; Parashurama, R, 2017)
"Extramammary Paget disease is a rare neoplastic condition that more commonly affects postmenopausal Caucasian women."( Bouceiro-Mendes, R; Correia-Fonseca, I; Mendonça-Sanches, M; Soares-de-Almeida, L, 2019)
"Extramammary Paget disease is a rare skin intraepithelial adenocarcinoma."( Jiang, C; Song, S, 2021)

Context

ExcerptReference
"The histogenesis of extramammary Paget's disease has long remained unresolved and controversial."( Haagensen, DE; Mazoujian, G; Pinkus, GS, 1984)
"Invasive cases of extramammary Paget's disease have a poor prognosis, owing to its rapid progression and resistance to irradiation and chemotherapy."( Chinuki, Y; Harada, Y; Kaneko, S; Kusatake, K; Mizumoto, K; Morita, E; Niihara, H, 2015)

Treatment

ExcerptReference
"No effective chemotherapy for advanced extramammary Paget's disease has yet been established."( Kawabata, I; Mabuchi, M; Niwa, K; Shimokawa, K; Tamaya, T; Yokoyama, Y, 1990)
"An effective chemotherapy for advanced extramammary Paget's disease has not yet been established."( Kariya, K; Schwartz, RA; Tsuji, T, 2004)
"In order to treat a patient with extramammary Paget's disease who had multiple metastases, 500 mg/day of 5-fluorouracil (7 days per week) and 5 mg/day of cisplatin (5 days per week) were administrated intravenously for 24 hours and 1 hour, respectively."( Kariya, K; Schwartz, RA; Tsuji, T, 2004)
"In one patient with extramammary Paget's disease and multiple metastases, low-dose FP therapy appeared to be beneficial."( Kariya, K; Schwartz, RA; Tsuji, T, 2004)
"Although some cases of extramammary Paget's disease (EMPD) also express HER2 protein, no case of EMPD has been reported to be treated with trastuzumab."( Hide, M; Hori, I; Kamegashira, A; Madokoro, N; Mihara, S; Noda, H; Shindo, H; Takahagi, S, 2009)
"In conclusion, photodynamic therapy for extramammary Paget's disease is not recommended as the first option except for scrotal cases or lesions < 4 cm in diameter."( Gao, T; Hu, X; Jiao, B; Li, C; Li, Q; Liao, W; Long, HA; Lv, Y; Qi, X; Qiao, H; Wang, L; Wang, S, 2010)
"Metastatic extramammary Paget's disease (EMPD) is a rare cancer with no validated systemic treatment."( Grothey, A; Phuoc, V, 2015)
"Invasive cases of extramammary Paget's disease have a poor prognosis, owing to its rapid progression and resistance to irradiation and chemotherapy."( Chinuki, Y; Harada, Y; Kaneko, S; Kusatake, K; Mizumoto, K; Morita, E; Niihara, H, 2015)
"In invasive extramammary Paget's disease (EMPD), distant metastases may develop and the condition may become fatal; however, no standardized treatment has been established."( Fujisawa, Y; Hatta, N; Hayashi, T; Kadono, T; Kiyohara, Y; Matsushita, S; Murata, Y; Ohara, K; Takenouchi, T; Uchi, H; Uhara, H; Yoshino, K, 2016)
"Patients with biopsy-proven recurrent extramammary Paget's disease presenting to the gynecology outpatient services at two participating institutions were recruited for conservative treatment with 5% imiquimod cream from 2007 to 2011."( Abu-Rustum, NR; Backes, FJ; Black, DR; Chi, DS; Cowan, RA; Eisenhauer, EL; Gardner, GJ; Hoang, LN; Leitao, MM; Park, KJ; Soslow, RA, 2016)
"Metastatic extramammary Paget's disease (EMPD) is a rare cancer with no standardized treatment."( Funakoshi, T; Hirai, I, 2017)
"A wide local excision is the standard treatment for extramammary Paget's disease (EMPD), though this treatment often leads to permanent anogenital mutilation and functional impairment."( Hida, T; Horimoto, K; Kato, J; Sato, S; Sawada, M; Uhara, H; Yamashita, T; Yoneta, A, 2018)
"Although topical therapies are used to treat extramammary Paget's disease (EMPD), reliable treatment outcomes and the effects of these therapies on subsequent surgical treatments are unclear."( Choi, S; Chung, KY; Oh, BH; Oh, Y; Roh, MR, 2021)

Research

Studies (342)

TimeframeStudies, This Condition (%)All Conditions %
pre-199059 (17.25)23.3326
1990's48 (14.04)12.5806
2000's75 (21.93)18.1394
2010's113 (33.04)28.8240
2020's47 (13.74)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
aminolevulinic acid0medium364
5-aminovaleric acid0low10
salicylic acid0low100
phytic acid0low20
bicalutamide0low10
cimetidine0low10
pentetic acid0low10
erythrosine0low20
etidronate0medium21
fluorouracil0low340
iohexol0low10
iomeprol0low10
isoniazid0low10
khellin0low10
methenamine0low10
nimesulide0low10
oxonic acid0low80
pamidronate0low20
protoporphyrin ix0low10
tazarotene0low10
tegafur0low80
thalidomide0low10
mitomycin0low90
estriol0low10
hydroxyproline0low30
cyanides0low10
edetic acid0low10
leucine0medium11
sulfan blue0low20
citrulline0low10
betamethasone0low10
hematoxylin0low10
dihydrotestosterone0low10
hematoporphyrin0low30
c.i. 425100low40
deoxycytidine0low10
carmine0low10
potassium hydroxide0low10
fluorescein0low20
fluorescein-5-isothiocyanate0low10
rhenium0medium11
silver0low10
technetium0low10
holmium0low10
zirconium0low10
camptothecin0low10
silver nitrate0low10
clodronic acid0low20
phenyl acetate0low10
triamcinolone0low10
tridemorph0low10
paclitaxel0low90
vindesine0low10
epirubicin0low60
propiconazole0low10
iso-sulfan blue0low10
imiquimod0medium702
cidofovir anhydrous0low10
gemcitabine0low10
tiludronic acid0low10
thomsen-friedenreich antigen0low10
metaperiodate0low20
iopamidol0low10
fluorodeoxyglucose f180low100
zoledronic acid0medium21
6-amino-1-hydroxyhexane-1,1-diphosphonate0low10
clobetasone butyrate0low10
ubenimex0medium11
homocysteine0medium11
technetium tc 99m hydroxymethylene diphosphonate0low10
methotrexate0medium21
docetaxel anhydrous0low200
methyl 5-aminolevulinate0low40
singlet oxygen0low10
technetium tc 99m pentetate0low10
biotin0low10
organophosphonates0low20
carboplatin0low50
glycogen0low20
inositol 3-phosphate0low10
griseofulvin0low10
tretinoin0low10
cefoxitin0low10
diethylstilbestrol0low10
epothilone a0low10
bromochloroacetic acid0low590
isomethyleugenol0low20
tamoxifen0low10
calcitriol0low10
etretinate0low10
sirolimus0low10
clobetasol0low10
strontium0low10
aconiazide0low10
phosphorus0low10
strontium radioisotopes0low10
25-hydroxyvitamin d 20medium11
selenium0low10
oxalates0low10
involucrin0low20
ixabepilone0low10
taxane0low10
mart-1 antigen0low40
2-amino-5-hydroxy-4-oxopentanoic acid0low10
indocyanine green0low50
acid phosphatase0low10
jaw0low10
glucagon0low10
glycolipids0low10
apatinib0low10
calcipotriene0low10
s 1 (combination)0low80
transforming growth factor beta0low20
cyclin d10low50
caseins0low20
lewis x antigen0low20
hyaluronoglucosaminidase0low20
vitamin b 120medium11
technetium tc 99m medronate0low20
muramidase0low20
exudates0low10
levoleucovorin0low20
folic acid0medium11
alcian blue0low40
phosphorus radioisotopes0low10

Protein Targets (1,121)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Gamma-aminobutyric acid receptor subunit rho-30001
thioredoxin reductase160016
NFKB1 protein, partial4004
arylsulfatase A100010
cytochrome P450 2D6 isoform 16006
Gamma-aminobutyric acid receptor subunit rho-10102
Gamma-aminobutyric acid receptor subunit rho-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor 10202
Glutamate receptor 20202
Glutamate receptor 30202
Glutamate receptor ionotropic, kainate 30202
Solute carrier family 15 member 10202
Glutamate receptor 40202
ATP-dependent phosphofructokinase140014
Geranylgeranyl pyrophosphate synthase0607
Farnesyl pyrophosphate synthase0808
Chain A, Beta-lactamase140014
bromodomain adjacent to zinc finger domain 2B6006
geminin360036
Solute carrier family 15 member 10202
Solute carrier family 15 member 20202
Vascular endothelial growth factor receptor 20101
pregnane X receptor7007
GLI family zinc finger 3290029
AR protein390039
progesterone receptor240024
cytochrome P450 family 3 subfamily A polypeptide 4190019
glucocorticoid receptor [Homo sapiens]260026
estrogen-related nuclear receptor alpha340034
farnesoid X nuclear receptor190019
pregnane X nuclear receptor220022
estrogen nuclear receptor alpha440044
vitamin D (1,25- dihydroxyvitamin D3) receptor210021
IDH1120012
aryl hydrocarbon receptor180018
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a210021
nuclear receptor subfamily 1, group I, member 2120012
thyroid hormone receptor beta isoform a100010
nuclear factor erythroid 2-related factor 2 isoform 2170017
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 1280028
ATP-binding cassette sub-family C member 3021021
Multidrug resistance-associated protein 4021023
Voltage-dependent calcium channel gamma-2 subunit240024
Bile salt export pump027027
Glucocorticoid receptor011012
Glycine receptor subunit alpha-10808
Glutamate receptor 2260026
Glycine receptor subunit beta0808
Glycine receptor subunit alpha-20808
Glycine receptor subunit alpha-30808
Canalicular multispecific organic anion transporter 1022023
ORF730011
RAR-related orphan receptor gamma290029
ATAD5 protein, partial140014
TDP1 protein330033
estrogen receptor 2 (ER beta)190019
EWS/FLI fusion protein150015
retinoid X nuclear receptor alpha250025
peroxisome proliferator activated receptor gamma230023
activating transcription factor 6160016
chromobox protein homolog 1180018
thyroid hormone receptor beta isoform 2270027
tyrosine-protein kinase Yes3003
nuclear receptor ROR-gamma isoform 1140014
Estrogen receptor07210
Cellular tumor antigen p53300030
Progesterone receptor0202
Progesterone receptor0314
Glucocorticoid receptor0202
Androgen receptor05312
Androgen receptor0819
Androgen receptor0213
Mineralocorticoid receptor0202
Testosterone 17-beta-dehydrogenase 30202
Progesterone receptor0202
ALK tyrosine kinase receptor0202
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, JmjC domain-containing histone demethylation protein 3A8008
apical membrane antigen 1, AMA17007
nonstructural protein 10202
green fluorescent protein, partial0101
vitamin D3 receptor isoform VDRA130013
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
aldehyde dehydrogenase 1 family, member A1140014
nuclear receptor subfamily 1, group I, member 3220022
retinoic acid nuclear receptor alpha variant 1260026
thyroid stimulating hormone receptor130013
Nuclear receptor ROR-gamma6118
ATPase family AAA domain-containing protein 5150015
Ataxin-2150015
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Ferritin light chain120012
Vitamin D3 receptor0011
USP1 protein, partial190019
PPM1D protein100010
Microtubule-associated protein tau130013
thioredoxin glutathione reductase6006
euchromatic histone-lysine N-methyltransferase 2240024
mitogen-activated protein kinase 17007
peripheral myelin protein 22190019
Interferon beta200020
Vitamin D-binding protein0011
Cytochrome P450 1A20315
Cytochrome P450 3A4011113
Cytochrome P450 2D60314
Vitamin D3 receptor0124
Cytochrome P450 2C9 0719
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0235
Cytochrome P450 2C190516
Kappa-type opioid receptor0011
Vitamin D3 receptor0011
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Chain A, HADH2 protein110011
Chain B, HADH2 protein110011
Chain A, 2-oxoglutarate Oxygenase110011
Chain A, Cruzipain4004
DNA topoisomerase 0101
15-lipoxygenase, partial6006
Fumarate hydratase100010
Thrombopoietin3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
thyroid stimulating hormone receptor9009
regulator of G-protein signaling 47007
polyprotein100010
67.9K protein160016
glucocerebrosidase5005
putative alpha-glucosidase1001
alpha-galactosidase6006
Bloom syndrome protein isoform 19009
lysosomal alpha-glucosidase preproprotein3003
peripheral myelin protein 22 isoform 14004
hemoglobin subunit beta2002
cellular tumor antigen p53 isoform a6006
cytochrome P450 2C19 precursor6006
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1100010
huntingtin isoform 22002
ras-related protein Rab-9A4004
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
serine/threonine-protein kinase mTOR isoform 13003
DNA polymerase iota isoform a (long)130013
survival motor neuron protein isoform d140014
cytochrome P450 3A4 isoform 1150015
M-phase phosphoprotein 88008
muscleblind-like protein 1 isoform 17007
histone acetyltransferase KAT2A isoform 1150015
relaxin receptor 1 isoform 12002
lethal factor (plasmid)6006
lamin isoform A-delta10190019
Gamma-aminobutyric acid receptor subunit pi150015
Telomerase reverse transcriptase0101
Serine/threonine-protein kinase Chk10022
Histone deacetylase 30202
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0002
DNA ligase0101
Integrin beta-35106
Integrin alpha-IIb5005
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 10218
DNA topoisomerase 2-alpha0229
Gamma-aminobutyric acid receptor subunit beta-1150015
Gamma-aminobutyric acid receptor subunit delta150015
Gamma-aminobutyric acid receptor subunit gamma-2150015
Gamma-aminobutyric acid receptor subunit alpha-5150015
Gamma-aminobutyric acid receptor subunit alpha-3150015
Gamma-aminobutyric acid receptor subunit gamma-1150015
Gamma-aminobutyric acid receptor subunit alpha-2150015
Type-2 restriction enzyme BamHI0101
Gamma-aminobutyric acid receptor subunit alpha-4150015
Gamma-aminobutyric acid receptor subunit gamma-3150015
Gamma-aminobutyric acid receptor subunit alpha-6150015
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
5-hydroxytryptamine receptor 2B0808
Type-2 restriction enzyme HindIII0101
D(1A) dopamine receptor2002
Histone deacetylase 40101
Ribonuclease pancreatic0101
Gamma-aminobutyric acid receptor subunit alpha-1150015
Gamma-aminobutyric acid receptor subunit beta-3150015
Gamma-aminobutyric acid receptor subunit beta-2150015
Inositol monophosphatase 14004
DNA topoisomerase 2-beta01210
DNA topoisomerase 10102
Histone deacetylase 10202
DNA topoisomerase 10101
Integrase 0202
Histone deacetylase 70101
GABA theta subunit150015
Histone deacetylase 20202
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80202
Gamma-aminobutyric acid receptor subunit epsilon150015
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE180018
Chain A, TYROSYL-DNA PHOSPHODIESTERASE110011
Chain A, Putative fructose-1,6-bisphosphate aldolase8008
acetylcholinesterase9009
phosphopantetheinyl transferase120012
G120012
cytochrome P450 2D6110011
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
DNA polymerase kappa isoform 19009
HLA class I histocompatibility antigen, B alpha chain 120012
Inositol hexakisphosphate kinase 1120012
cytochrome P450 2C9, partial120012
Chain A, ATP-DEPENDENT DNA HELICASE Q16006
Luciferase120012
interleukin 86006
GLS protein7007
luciferase2002
potassium voltage-gated channel subfamily H member 2 isoform d9009
flap endonuclease 19009
eyes absent homolog 2 isoform a2002
Tyrosine-protein phosphatase non-receptor type 10204
Glutamate receptor 13003
Glutamate receptor 33003
Glutamate receptor 43003
Tyrosine-protein phosphatase 10101
Alpha-synuclein6208
C-terminal-binding protein 11001
Thymidine kinase 0101
Solute carrier family 22 member 60304
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Thymidine kinase0001
Solute carrier family 22 member 60305
muscarinic acetylcholine receptor M12002
Solute carrier family 22 member 10101
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0303
Solute carrier family 22 member 20101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB108113
Potassium-transporting ATPase alpha chain 10101
ATP-dependent translocase ABCB10404
Histamine H2 receptor0606
Histamine H1 receptor0011
Histamine H2 receptor92112
Potassium-transporting ATPase subunit beta0101
Cytochrome P450 2J20202
Aldehyde oxidase0202
Solute carrier family 22 member 10202
Multidrug and toxin extrusion protein 20101
Solute carrier family 22 member 80305
Multidrug and toxin extrusion protein 10101
Histamine H4 receptor0101
Solute carrier family 22 member 110102
Solute carrier family 22 member 20202
Solute carrier family 22 member 40101
Solute carrier family 22 member 80202
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10202
General amino-acid permease GAP10001
Nitric oxide synthase, brain0101
Nitric oxide synthase, brain 0101
glp-1 receptor, partial120012
hypoxia-inducible factor 1 alpha subunit130013
nonstructural protein 15005
neuropeptide S receptor isoform A4004
Guanine nucleotide-binding protein G3003
Type IV secretion-like conjugative transfer relaxase protein TraI 0202
72 kDa type IV collagenase0404
Stromelysin-10112
Matrix metalloproteinase-90303
Macrophage metalloelastase0101
endonuclease IV3003
PAX80002
Smad36006
peroxisome proliferator-activated receptor delta200020
v-jun sarcoma virus 17 oncogene homolog (avian)110011
nuclear receptor subfamily 0 group B member 10202
cytochrome P450 2C9 precursor3003
atrial natriuretic peptide receptor 2 precursor2002
steroidogenic factor 10202
caspase-1 isoform alpha precursor2002
Solute carrier family 22 member 30101
Tubulin alpha-1A chain0438
Tubulin beta chain0437
Plasma kallikrein0102
Tubulin beta-4A chain04411
Tubulin beta chain04411
Tubulin alpha-3C chain04411
Serine/threonine-protein kinase pim-10112
Tubulin alpha-1B chain04411
Tubulin alpha-4A chain04411
Tubulin beta-4B chain04411
Vesicular acetylcholine transporter0101
Tubulin beta-3 chain05412
Tubulin beta-2A chain04411
Tubulin polymerization-promoting protein0011
Tubulin beta-8 chain04411
Tubulin beta-2B chain0417
Tubulin alpha-3E chain04411
Tubulin alpha-1A chain04411
Similar to alpha-tubulin isoform 1 0316
Similar to alpha-tubulin isoform 1 0305
CREB-binding protein1001
Tubulin alpha-1C chain04411
Tubulin beta-6 chain04411
Tubulin beta-2B chain04411
Tubulin beta-1 chain04411
Carbonic anhydrase 10707
Carbonic anhydrase 20718
Carbonic anhydrase 40404
Carbonic anhydrase0202
Carbonic anhydrase 150303
Thymidine kinase 2 0101
Deoxycytidine kinase0013
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0011
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
Histone H2A.x140014
heat shock protein beta-19009
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
serine/threonine-protein kinase PLK13003
high affinity choline transporter 1 isoform a0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 12103
Polyunsaturated fatty acid lipoxygenase ALOX15B7007
5-hydroxytryptamine receptor 40404
Nuclear receptor subfamily 1 group I member 20112
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Tyrosine-protein kinase Fyn0415
Aldo-keto reductase family 1 member B10404
Beta-1 adrenergic receptor0404
Alpha-2A adrenergic receptor0404
Polyunsaturated fatty acid 5-lipoxygenase0303
Adenosine receptor A30606
Muscarinic acetylcholine receptor M10404
Polyunsaturated fatty acid lipoxygenase ALOX150303
D(2) dopamine receptor0404
Alpha-1B adrenergic receptor0606
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30404
Substance-K receptor0606
D(1A) dopamine receptor0404
Acetylcholinesterase0202
Prostaglandin G/H synthase 10404
Sodium-dependent noradrenaline transporter 0415
Thromboxane-A synthase 0202
Alpha-1D adrenergic receptor0606
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
Adenosine receptor A2a0606
Adenosine receptor A10404
Sodium-dependent serotonin transporter0606
Mu-type opioid receptor0404
D(3) dopamine receptor0404
Vasopressin V1a receptor0202
Delta-type opioid receptor0606
Kappa-type opioid receptor0404
Alpha-1A adrenergic receptor0606
5-hydroxytryptamine receptor 60404
Spike glycoprotein120214
Estrogen-related receptor gamma0112
Disintegrin and metalloproteinase domain-containing protein 171001
Sodium-dependent dopamine transporter 0606
TAR DNA-binding protein 435005
UDP-glucose 4-epimerase0101
Mitogen-activated protein kinase 140112
Estrogen receptor beta0426
Broad substrate specificity ATP-binding cassette transporter ABCG20203
Cysteinyl leukotriene receptor 10202
Chain A, Sex Hormone-Binding Globulin0011
thyrotropin-releasing hormone receptor6006
transcriptional regulator ERG isoform 33003
Sex hormone-binding globulin0123
Corticosteroid-binding globulin0202
Mineralocorticoid receptor 0101
Sex hormone-binding globulin0101
Aromatase0304
Angiotensin-converting enzyme0112
Cannabinoid receptor 20101
G-protein coupled bile acid receptor 10011
Muscarinic acetylcholine receptor0101
Neuropeptide FF receptor 20001
SMAD family member 2110011
SMAD family member 3110011
caspase 7, apoptosis-related cysteine protease7007
caspase-37007
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
urokinase-type plasminogen activator precursor8008
plasminogen precursor8008
urokinase plasminogen activator surface receptor precursor8008
Vpr3003
Rap guanine nucleotide exchange factor 32002
Glutathione S-transferase omega-10101
Serum paraoxonase/arylesterase 10303
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20202
Eyes absent homolog 20101
Amyloid-beta precursor protein1203
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Genome polyprotein 0202
UDP-glucuronosyltransferase 2B70103
Genome polyprotein 0112
chaperonin-containing TCP-1 beta subunit homolog2002
hypothetical protein, conserved3003
lethal(3)malignant brain tumor-like protein 1 isoform I2002
Flavin reductase (NADPH)0011
large T antigen0202
Solute carrier organic anion transporter family member 1A10101
Lanosterol 14-alpha demethylase0011
Olfactory receptor 51E20011
UDP-glucuronosyltransferase 1A100001
acid sphingomyelinase3003
LMP1 [Human herpesvirus 4]0001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0202
transactivating tegument protein VP16 [Human herpesvirus 1]0202
nuclear receptor coactivator 3 isoform a0202
Regulatory protein E20022
DNA topoisomerase 20001
UDP-glucuronosyltransferase 1A1 0102
Glutamate receptor ionotropic, NMDA 1 0001
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
DNA topoisomerase 2-alpha 0001
Glutamate receptor ionotropic, NMDA 2D0001
Glutamate receptor ionotropic, NMDA 3B0001
Solute carrier organic anion transporter family member 1B30405
Glutamate receptor ionotropic, NMDA 3A0001
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
Solute carrier family 22 member 80001
Epidermal growth factor receptor0314
Thymidylate synthase0505
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
DNA polymerase beta5005
Thymidylate synthase0606
Dihydrofolate reductase0336
Aldo-keto reductase family 1 member B10202
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0123
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Equilibrative nucleoside transporter 10101
Angiotensin-converting enzyme 2 0022
Heme oxygenase 1 0101
Heme oxygenase 20101
Lanosterol 14-alpha demethylase0101
Chain E, Fibrin beta chain0101
Chain A, RNA-directed RNA polymerase NS50202
WRN2002
Mcl-10101
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
alkaline phosphatase, intestinal0011
pyruvate kinase2002
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
CDK50001
serine-protein kinase ATM isoform a1001
major prion protein preproprotein Prp precursor0101
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0011
glucose-6-phosphate 1-dehydrogenase isoform b0101
intestinal alkaline phosphatase precursor0011
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
DNA polymerase eta isoform 14004
Vif0101
Tat0101
alkaline phosphatase, germ cell type preproprotein0011
endoribonuclease toxin MazF0011
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Pyruvate kinase PKM0101
Endothelin receptor type B1001
Endothelin-1 receptor1001
phosphoglycerate kinase3003
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10203
Amino acid transporter0101
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
histone deacetylase 9 isoform 32002
3-oxoacyl-[acyl-carrier-protein] synthase 3 0101
N-glycosylase/DNA lyase0101
Polyphenol oxidase 20203
Bile salt export pump0303
Myeloperoxidase0202
Formamidopyrimidine-DNA glycosylase0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Cytochrome P450 2C80101
Cytochrome P450 2A60101
Macrophage migration inhibitory factor0101
Endonuclease III-like protein 10101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
Enoyl-[acyl-carrier-protein] reductase [NADH]0102
Pantothenate synthetase0101
Isocitrate lyase0101
Putative FAD-containing monooxygenase MymA0101
Dihydrofolate reductase0202
Endonuclease 8-like 10101
Apoptosis regulator Bcl-20112
Chymotrypsinogen A0101
GALC protein2002
importin subunit beta-1 isoform 13003
snurportin-13003
GTP-binding nuclear protein Ran isoform 11001
Cytochrome P450 1A10202
Cytochrome P450 1B10101
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Large neutral amino acids transporter small subunit 10101
Phospholipase A-2-activating protein0101
HLA class I histocompatibility antigen, A alpha chain 0101
5-hydroxytryptamine receptor 2C0203
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2B0101
Gastrin/cholecystokinin type B receptor0101
Carbonic anhydrase 5A, mitochondrial0202
Carbonic anhydrase 90303
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0202
Thymidylate synthase 0202
polyunsaturated fatty acid lipoxygenase ALOX121001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0304
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0304
Thymidylate synthase0303
Tyrosine-protein kinase ABL10123
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0202
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0202
Dihydrofolate reductase0303
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30303
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0404
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0303
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30202
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0304
Protein-arginine deiminase type-40101
Indoleamine 2,3-dioxygenase 10101
Albumin0202
Interstitial collagenase0101
Prostaglandin G/H synthase 10303
Leukotriene A-4 hydrolase0314
Prostaglandin G/H synthase 20202
Prostaglandin G/H synthase 20202
NPC intracellular cholesterol transporter 1 precursor3003
Receptor tyrosine-protein kinase erbB-20202
Integrin alpha-V 0101
60 kDa chaperonin0303
Botulinum neurotoxin type A 0101
60 kDa heat shock protein, mitochondrial0303
Fibroblast growth factor receptor 10112
Proto-oncogene tyrosine-protein kinase Src0112
UDP-glucuronosyltransferase 1-60101
UDP-glucuronosyltransferase 1A40102
Cholecystokinin receptor type A0202
Melanocortin receptor 50404
UDP-glucuronosyltransferase 2B10 0101
10 kDa heat shock protein, mitochondrial0303
Bcl-2-like protein 10101
Tyrosine-protein kinase Mer0112
Thiosulfate sulfurtransferase0303
Beta-tubulin 0101
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Solute carrier organic anion transporter family member 1B10303
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0505
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Chain A, Thymidylate Synthase0101
Serine hydroxymethyltransferase, cytosolic0112
Thymidylate synthase 0101
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
Regulatory protein E20011
Regulatory protein E20011
Prostaglandin G/H synthase 20101
Calcium-activated potassium channel subunit alpha-10101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
SUMO-10101
isocitrate dehydrogenase 1, partial2002
tumor susceptibility gene 101 protein1001
POsterior Segregation0011
chaperonin GroEL1001
Exoribonuclease H 0101
Coproheme decarboxylase0011
Protease 0101
Single-stranded DNA cytosine deaminase1001
Zinc finger protein mex-50011
Butyrophilin subfamily 3 member A10023
4-hydroxy-3-methylbut-2-enyl diphosphate reductase0101
Farnesyl diphosphate synthase0101
Farnesyl pyrophosphate synthase 0202
H0202
Phosphotransferase 0101
Farnesyl diphosphate synthase0101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Carbonic anhydrase 120202
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Carbonic anhydrase 30101
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Estrogen receptor0001
Carbonic anhydrase 60101
Cystathionine gamma-lyase0101
Carbonic anhydrase 70101
5'-AMP-activated protein kinase subunit gamma-10012
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20012
Carbonic anhydrase 140202
Carbonic anhydrase 5B, mitochondrial0101
5'-AMP-activated protein kinase subunit beta-10001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30112
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
High affinity nerve growth factor receptor0011
ADP/ATP translocase 20011
Protein kinase C beta type0112
Insulin receptor0011
Tyrosine-protein kinase Lck0112
Cyclin-dependent kinase 10011
Eukaryotic translation initiation factor 4E0011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0112
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10112
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0112
Exosome RNA helicase MTR40011
Serine/threonine-protein kinase mTOR0112
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Protein kinase C theta type0112
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0112
Protein kinase C delta type0112
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Serine/threonine-protein kinase 40011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Regulatory-associated protein of mTOR0101
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Target of rapamycin complex subunit LST80101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase mTOR 0101
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
protein AF-9 isoform a0001
Chain A, CES1 protein0101
DNA polymerase III, partial1001
Caspase-72002
interferon gamma precursor0001
D(1A) dopamine receptor1001
caspase-32002
ubiquitin-conjugating enzyme E2 N0101
streptokinase A precursor0011
Lysosomal acid glucosylceramidase0011
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Estrogen receptor0012
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1A0404
Cytochrome P450 2B60101
D(4) dopamine receptor0202
Protein kinase C eta type0101
Substance-P receptor0202
5-hydroxytryptamine receptor 1B0202
B2 bradykinin receptor0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 30202
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Potassium voltage-gated channel subfamily H member 20202
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Nuclear receptor subfamily 3 group C member 3 0202
Sigma non-opioid intracellular receptor 10202
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Retinoic acid receptor alpha0238
Retinoic acid receptor beta0238
Retinoic acid receptor gamma 0238
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Neutrophil collagenase0202
Matrix metalloproteinase-140202
Chain A, Nuclear Receptor ROR-beta0101
Parkin1001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
Retinoic acid receptor alpha0123
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Alpha-1D adrenergic receptor0101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
procathepsin L isoform 1 preproprotein0101
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Chain A, Bacterial leucyl aminopeptidase0101
beta-2 adrenergic receptor1001
Aminopeptidase B0202
M1 family aminopeptidase0202
Cytosol aminopeptidase0202
Phospholipase A2, membrane associated0101
Aminopeptidase N0202
Aminopeptidase N0202
Aminopeptidase N 0101
Interleukin-1 receptor antagonist protein0101
Dipeptidyl peptidase 40101
Cytosol aminopeptidase0202
Puromycin-sensitive aminopeptidase0101
Aminopeptidase N0202
Leucyl-cystinyl aminopeptidase0101
Bacterial leucyl aminopeptidase0202
Leukotriene B4 receptor 10101
Endoplasmic reticulum aminopeptidase 20101
Aminopeptidase B0101
Endoplasmic reticulum aminopeptidase 10101
Farnesyl diphosphate synthase0101
Geranylgeranyl pyrophosphate synthase0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]