Page last updated: 2024-09-27

Exsanguinating Hemorrhage

Rapid and extreme blood loss leading to HEMORRHAGIC SHOCK.

Synonyms(2)

Synonym
Exsanguination
Exsanguinating Hemorrhage

Research Excerpts

Research

Studies (58)

TimeframeStudies, This Condition (%)All Conditions %
pre-19909 (15.52)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's40 (68.97)28.8240
2020's9 (15.52)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low20
lactic acid0low10
hydrogen carbonate0low10
n-methyl-3,4-methylenedioxyamphetamine0low10
barbital0low10
lidocaine0low10
isoguvacine0low10
pentobarbital0low10
tranexamic acid0medium84
prednisolone0low10
malondialdehyde0low10
dronabinol0low10
enbucrilate0low10
4-methoxyamphetamine0low20
fomesafen0low10
adenosine0low10
fibrinogen0medium61
centhaquine0low10
aminopterin0low10
cortisone0low10
thiopental0low10
lithium0low10
phenylephrine hydrochloride0low10
silicon0low10
heroin0low10
radium0low10
cardiovascular agents0low10
11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid0low10
warfarin0low10
cyclosporine0low10

Protein Targets (375)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
5-hydroxytryptamine receptor 2C0113
5-hydroxytryptamine receptor 2A0112
5-hydroxytryptamine receptor 1A0112
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0112
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0224
Sodium-dependent serotonin transporter0213
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein9009
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 43003
glucocorticoid receptor [Homo sapiens]7007
retinoid X nuclear receptor alpha4004
estrogen nuclear receptor alpha100010
NPYLR7B0011
arylsulfatase A1001
IDH13003
Histone H2A.x3003
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 12002
flap endonuclease 13003
nuclear receptor ROR-gamma isoform 11001
peripheral myelin protein 222002
survival motor neuron protein isoform d3003
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit2002
Rap guanine nucleotide exchange factor 31001
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0101
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30225
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Glutamate receptor 22013
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A10112
Adenosine receptor A30101
Adenosine receptor A2a0124
Adenosine receptor A2b0012
Adenosine receptor A2b0112
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A10225
Adenosine receptor A2a0112
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10011
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
hypoxia-inducible factor 1 alpha subunit4004
SMAD family member 21001
SMAD family member 31001
TDP1 protein6006
nuclear receptor subfamily 1, group I, member 31001
estrogen-related nuclear receptor alpha6006
farnesoid X nuclear receptor1001
pregnane X nuclear receptor6006
peroxisome proliferator-activated receptor delta2002
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
activating transcription factor 61001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
thyroid hormone receptor beta isoform 23003
heat shock protein beta-12002
nuclear factor erythroid 2-related factor 2 isoform 14004
Dihydrofolate reductase0202
Dihydrofolate reductase0203
Dihydrofolate reductase0102
Cellular tumor antigen p536006
Dihydrofolate reductase0101
Folylpolyglutamate synthase, mitochondrial0102
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0002
acetylcholinesterase2002
cytochrome P450 family 3 subfamily A polypeptide 44004
histone acetyltransferase KAT2A isoform 14004
lamin isoform A-delta105005
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
endonuclease IV1001
dopamine D1 receptor1001
thioredoxin reductase4004
pregnane X receptor1001
RAR-related orphan receptor gamma6006
GLS protein3003
GLI family zinc finger 34004
aldehyde dehydrogenase 1 family, member A15005
progesterone receptor4004
retinoic acid nuclear receptor alpha variant 14004
euchromatic histone-lysine N-methyltransferase 24004
v-jun sarcoma virus 17 oncogene homolog (avian)3003
peripheral myelin protein 22 isoform 11001
atrial natriuretic peptide receptor 1 precursor2002
chromobox protein homolog 13003
geminin4004
cytochrome P450 3A4 isoform 13003
M-phase phosphoprotein 81001
muscarinic acetylcholine receptor M12002
Gamma-aminobutyric acid receptor subunit pi3104
Bile salt export pump0505
Glucocorticoid receptor04110
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0202
Gamma-aminobutyric acid receptor subunit beta-13104
Gamma-aminobutyric acid receptor subunit delta3104
Gamma-aminobutyric acid receptor subunit gamma-23104
Gamma-aminobutyric acid receptor subunit alpha-53104
Gamma-aminobutyric acid receptor subunit alpha-33104
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Gamma-aminobutyric acid receptor subunit gamma-13104
Gamma-aminobutyric acid receptor subunit alpha-23104
Glycine receptor subunit alpha-30404
Gamma-aminobutyric acid receptor subunit alpha-43104
Gamma-aminobutyric acid receptor subunit gamma-33104
Gamma-aminobutyric acid receptor subunit alpha-63104
Gamma-aminobutyric acid receptor subunit alpha-13104
Gamma-aminobutyric acid receptor subunit beta-33104
Gamma-aminobutyric acid receptor subunit beta-23104
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 431001
GABA theta subunit3104
Multidrug and toxin extrusion protein 10202
Gamma-aminobutyric acid receptor subunit epsilon3104
aryl hydrocarbon receptor2002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a2002
potassium voltage-gated channel subfamily H member 2 isoform d1001
Fatty-acid amide hydrolase 10101
Nuclear receptor subfamily 1 group I member 20011
Transient receptor potential cation channel subfamily A member 10001
L-lactate dehydrogenase A chain0101
Fatty acid-binding protein, liver0101
Glutamate receptor 10011
Glutamate receptor 30011
Glutamate receptor 40011
Cannabinoid receptor 10213
Cannabinoid receptor 10214
Glycine receptor subunit alpha-10011
Cannabinoid receptor 2 0214
D(3) dopamine receptor0011
Cannabinoid receptor 10101
Cannabinoid receptor 20112
N-arachidonyl glycine receptor0011
Transient receptor potential cation channel subfamily A member 10011
Lysophosphatidylserine lipase ABHD120101
ATPase family AAA domain-containing protein 52002
Monoglyceride lipase0101
Ataxin-22002
Monoacylglycerol lipase ABHD60101
Cannabinoid receptor 20202
G-protein coupled receptor 550112
Luciferase1001
Liver carboxylesterase 10001
Carbonic anhydrase 10303
Carbonic anhydrase 20303
Carbonic anhydrase 40202
Carbonic anhydrase0101
Carbonic anhydrase 150202
thyroid stimulating hormone receptor1001
hexokinase-4 isoform 11001
D(1A) dopamine receptor1001
glucokinase regulatory protein1001
tumor susceptibility gene 101 protein1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20123
Gamma-aminobutyric acid receptor subunit rho-10011
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50112
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20123
Gamma-aminobutyric acid receptor subunit beta-20123
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60112
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid type B receptor subunit 10101
ATP-dependent phosphofructokinase1001
estrogen receptor 2 (ER beta)1001
cytochrome P450 2D62002
thyroid stimulating hormone receptor2002
cellular tumor antigen p53 isoform a1001
Integrin beta-31001
Integrin alpha-IIb1001
Chain A, Beta-lactamase2002
Microtubule-associated protein tau1001
Potassium channel subfamily K member 30101
ATP-binding cassette sub-family C member 30202
Multidrug resistance-associated protein 40202
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Potassium voltage-gated channel subfamily H member 20202
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Canalicular multispecific organic anion transporter 10202
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2D60102
Aldo-keto reductase family 1 member B10101
Sodium-dependent noradrenaline transporter 0213
Sodium-dependent dopamine transporter0011
Sodium-dependent dopamine transporter 0213
Trace amine-associated receptor 10011
Chain A, 2-oxoglutarate Oxygenase4004
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
glp-1 receptor, partial1001
GALC protein1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
beta-2 adrenergic receptor1001
Bloom syndrome protein isoform 11001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Spike glycoprotein1001
luciferase0001
nuclear receptor subfamily 1, group I, member 21001
nuclear factor erythroid 2-related factor 2 isoform 21001
Interferon beta2002
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0202
Glutamine synthetase0011
Androgen receptor0101
Histamine H1 receptor0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
5-hydroxytryptamine receptor 2A0011
5-hydroxytryptamine receptor 2C0011
5-hydroxytryptamine receptor 2B0011
chaperonin-containing TCP-1 beta subunit homolog1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
Carbonic anhydrase 120101
5'-AMP-activated protein kinase subunit beta-20001
Bile salt export pump0101
Albumin0112
Polymerase acidic protein0011
Carbonic anhydrase 30101
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60101
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase 90101
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
5'-AMP-activated protein kinase subunit beta-10001
Chain A, Ferritin light chain1001
USP1 protein, partial1001
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Fatty-acid amide hydrolase 10101
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
EWS/FLI fusion protein2002
Plasminogen0213
Urokinase-type plasminogen activator0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
PPM1D protein1001
thyroid hormone receptor beta isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]