Page last updated: 2024-09-27

Aesthesioneuroblastoma

Synonyms(6)

Synonym
Paranasal Sinus-Nasal Cavity Esthesioneuroblastoma
Esthesioneuroblastoma
Neuroblastoma, Olfactory
Aesthesioneuroblastoma
Esthesioneuroblastoma, Paranasal Sinus-Nasal Cavity
Olfactory Neuroblastoma

Research Excerpts

Overview

ExcerptReference
"Olfactory neuroblastoma is an uncommon intranasal neoplasm that has not been previously documented to invade the oral cavity."( Hardy, DA; Myers, SL; Shiffman, J; Wiebe, CB, 1994)
"Esthesioneuroblastomas are radiocurable tumors."( Eich, HT; Eich, PD; Micke, O; Müller, R; Staar, S; Stützer, H, 2001)
"Esthesioneuroblastoma is a rare tumor, which in many cases is diagnosed at an advanced stage with an high recurrence rate and incidence of metastases."( Constantinidis, J; Iro, H; Koch, M; Koester, M; Schänzer, A, 2002)
"Esthesioneuroblastoma is an uncommon malignancy of neural crest origin arising in the upper nasal cavity."( Amdur, RJ; Hinerman, RW; Mendenhall, WM; Monroe, AT; Morris, CG, 2003)
"Esthesioneuroblastoma is an uncommon malignancy of the nasal vault with a treatment regimen consisting of surgical resection followed by radiotherapy for primary lesions and addition of chemotherapy for patients with advanced, recurrent or metastatic lesions."( Donahue, JE; Park, MC; Sampath, P; Weaver, CE, 2006)
"Esthesioneuroblastoma is a rare malignancy arising from the olfactory mucosa in the nasal fossa, which can invade the orbit producing ophthalmic symptoms and signs."( Crompton, J; Laforest, C; Leibovitch, I; Selva, D, 2005)
"Orbital invasion by esthesioneuroblastoma is not uncommon."( Crompton, J; Laforest, C; Leibovitch, I; Selva, D, 2005)
"Esthesioneuroblastoma is a rare and clinically variable tumor of nasal sinus and skull base and challenging for modern multidisciplinary therapy."( Constantinidis, J; Dimmler, A; Iro, H; Koch, M; Strauss, C, 2006)
"Therapy of esthesioneuroblastoma is challenging because of rarity and biologic variability of the tumor and and because of lack of a standard therapy."( Constantinidis, J; Dimmler, A; Iro, H; Koch, M; Strauss, C, 2006)
"Olfactory neuroblastomas are rare, slow-growing malignant tumors, usually diagnosed at advanced stages."( An, JH; Cho, YM; Choi, SH; Chung, JH; Jang, HC; Jeon, KH; Koo, BK; Lee, CH; Lim, S, 2008)
"Esthesioneuroblastoma is a rare malignancy that arises in the olfactory epithelium."( Loehrl, TA; Michel, MA; Tseng, J, 2009)
"Esthesioneuroblastoma is an uncommon malignant tumor."( Huang, WT; Wang, DH; Wang, SY; Zhang, M; Zhou, L, 2010)
"Olfactory neuroblastoma is a rare paranasal sinus malignancy."( Bridger, GP; Broadley, K; Meagher, NS; Smee, RI; Williams, JR, 2011)
"Olfactory neuroblastoma is an uncommon malignant neoplasm of the superior nasal cavity."( Hoshikawa, H; Nishiyama, Y; Tanaka, K; Yamamoto, Y, 2014)
"Esthesioneuroblastoma is a rare malignant tumor of sinonasal origin."( Gallia, GL; Ishii, M; Reh, DD; Roxbury, CR, 2016)
"Esthesioneuroblastoma is a rare neuroectodermic tumor of the olfactory tract."( Aubert, S; Baillet, C; Do Cao, C; Jannin, A; Turpin, A, 2018)
"Esthesioneuroblastoma is a rare neoplasm arising from the neural crest cells of olfactory epithelium mostly in the nasal vault."( Kakkar, A; Kumar, R; Shamim, SA; Sharma, P; Tripathy, S, 2019)
"Esthesioneuroblastoma is a rare malignant tumor arising from olfactory neuroepithelium."( Albano, D; Bertagna, F; Bertoli, M; Dondi, F; Giubbini, R, 2021)

Treatment

ExcerptReference
"Successful treatment of olfactory neuroblastoma is more often described in less advanced tumors and mostly in adults."( Armata, J; Balwierz, W; Cwiklińska, M; Załeska-Czepko, E, 1995)
"Eleven olfactory neuroblastomas treated at Helsinki University Central Hospital between 1970 and 1991 were reviewed retrospectively."( Jekunen, AP; Kairemo, KJ; Kajanti, MJ; Lehtonen, HP, 1996)
"Hyams' grading of esthesioneuroblastoma tumors seems to be important in predicting response to chemotherapy."( Buckner, JC; Lewis, JE; McElroy, EA, 1998)
"We report a 56-year-old man in whom an olfactory neuroblastoma with epithelial and endocrine differentiation transformed into a mature ganglioneuroma after chemoradiotherapy."( Mineta, H; Miura, K; Tsutsui, Y; Yokota, N, 2001)
"Our data suggest that metastatic esthesioneuroblastoma is sensitive to platinum-based chemotherapy."( de Vos, FY; de Vries, EG; Willemse, PH, 2003)
"Therapy of esthesioneuroblastoma is challenging because of rarity and biologic variability of the tumor and and because of lack of a standard therapy."( Constantinidis, J; Dimmler, A; Iro, H; Koch, M; Strauss, C, 2006)
"Chemotherapy for olfactory neuroblastoma with irinotecan plus docetaxel is safe and manageable."( Fujii, S; Hayashi, R; Kawashima, M; Kiyota, N; Minami, H; Ogino, T; Ohtsu, A; Tahara, M, 2008)
"Using primary esthesioneuroblastoma cells we analyzed the anti-tumor potential and the mechanism employed by Bortezomib in combination with TRAIL for the treatment of this rare but aggressive tumor."( Ahnert, P; Bauer, M; Bockmuehl, U; Erdal, H; Ganten, TM; Holland, H; Koschny, R; Krupp, W; Meixensberger, J; Stremmel, W; Sykora, J; Walczak, H, 2010)
"We successfully treated two cases of olfactory neuroblastoma by endoscopic-assisted craniotomy with primary dural closure and anterior cranial base reconstruction using a multi-layered flap technique."( Kono, M; Ogawa, K; Toda, M; Tomio, R; Tomita, T; Yazawa, M; Yoshida, K, 2014)
"Advanced-stage olfactory neuroblastoma requires multimodal therapy for optimal outcomes."( Adappa, ND; Gallagher, R; Harvey, RJ; Havas, T; Nalavenkata, S; Palmer, JN; Purkey, MT; Sacks, R; Schlosser, RJ; Smee, R; Snyderman, C; Wang, EW; Woodworth, BA, 2017)

Research

Studies (98)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (1.02)23.3326
1990's9 (9.18)12.5806
2000's35 (35.71)18.1394
2010's42 (42.86)28.8240
2020's11 (11.22)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0low20
hydrogen carbonate0low10
methanol0low10
carmustine0low20
fluorouracil0low10
ifosfamide0low40
ketoconazole0low20
lomustine0medium21
metyrapone0low10
procarbazine0low10
temozolomide0low20
thiotepa0low10
mitomycin0low10
cytarabine0low20
phencyclidine0low10
methylprednisolone0low10
pyrroles0low20
indazoles0low10
pyrazines0low10
gadolinium0low10
camptothecin0low10
etoposide0low150
epirubicin0low10
propiconazole0low90
topotecan0low10
irinotecan0low10
3-iodobenzylguanidine0low10
fluorodeoxyglucose f180low130
methotrexate0low20
docetaxel anhydrous0low10
edotreotide0low10
bortezomib0low10
carboplatin0medium61
dactinomycin0low20
bromochloroacetic acid0low80
arginine vasopressin0low20
leuprolide0low10
phenylephrine hydrochloride0low100
su 112480low20
gadolinium dtpa0low10
pazopanib0low10
losartan potassium0low10
pituitrin0low20
mesna0low10
gdc 04490low10
gallium ga 68 dotatate0low20
lutetium lu 177 dotatate0low10
68ga-dotanoc0low10
levoleucovorin0low10
dacarbazine0low40
eye0low20

Protein Targets (1,094)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
dopamine D1 receptor2002
thioredoxin reductase110011
GLS protein3003
Thrombopoietin3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
cytochrome P450 2D6 isoform 11001
cytochrome P450 2C19 precursor3003
ras-related protein Rab-9A2002
histone acetyltransferase KAT2A isoform 15005
lethal factor (plasmid)2002
POU domain, class 2, transcription factor 10001
Spike glycoprotein9009
ATP-dependent phosphofructokinase8008
vitamin D3 receptor isoform VDRA6006
peripheral myelin protein 227007
ATP-binding cassette sub-family C member 3019019
Multidrug resistance-associated protein 4019020
Bile salt export pump022022
Translocator protein0213
Vasopressin V2 receptor0214
Oxytocin receptor0112
Vasopressin V1a receptor0022
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Vasopressin V2 receptor0011
Vasopressin V1b receptor0113
Translocator protein0102
Oxytocin receptor0101
Vasopressin V2 receptor 0112
Canalicular multispecific organic anion transporter 1019020
Chain H, Proteasome component PUP10101
Chain I, Proteasome component PUP30101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Chain K, Proteasome component PRE20101
Chain L, Proteasome component C50101
Proteasome subunit beta type-110101
RAR-related orphan receptor gamma150015
Fumarate hydratase7007
PPM1D protein8008
TDP1 protein170017
AR protein170017
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)8008
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor110011
cytochrome P450 family 3 subfamily A polypeptide 4100010
EWS/FLI fusion protein170017
glucocorticoid receptor [Homo sapiens]140014
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha130013
estrogen-related nuclear receptor alpha180018
farnesoid X nuclear receptor9009
pregnane X nuclear receptor120012
estrogen nuclear receptor alpha150015
polyprotein7007
peroxisome proliferator-activated receptor delta9009
peroxisome proliferator activated receptor gamma130013
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
caspase-35005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
nuclear receptor subfamily 1, group I, member 24004
Histone H2A.x8008
Caspase-72002
caspase-32002
thyroid hormone receptor beta isoform 2130013
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 1130013
26S proteasome non-ATPase regulatory subunit 110101
26S proteasome non-ATPase regulatory subunit 120101
26S proteasome non-ATPase regulatory subunit 140101
Proteasome subunit alpha type-70101
Histone deacetylase 30202
26S proteasome non-ATPase regulatory subunit 30101
Carbonic anhydrase 120303
Voltage-dependent calcium channel gamma-2 subunit9009
Prothrombin0103
Chymotrypsinogen A0202
Carbonic anhydrase 10505
Carbonic anhydrase 20516
Interferon beta120012
Cellular tumor antigen p53140014
Carbonic anhydrase 30202
Cathepsin B0101
Neutrophil elastase0101
Cathepsin G0202
Lysosomal protective protein0101
Chymotrypsinogen B0101
26S proteasome regulatory subunit 6A0101
Glutamate receptor 29009
Nuclear factor NF-kappa-B p105 subunit0101
Proteasome subunit beta type-10102
Carbonic anhydrase 40303
Carbonic anhydrase 60202
Chymase0101
Proteasome subunit alpha type-10101
Proteasome subunit alpha type-20101
Proteasome subunit alpha type-30101
Proteasome subunit alpha type-40101
Proteasome subunit beta type-80101
Proteasome subunit beta type-80101
Proteasome subunit beta type-90101
Proteasome subunit alpha type-50101
Proteasome subunit beta type-40101
Proteasome subunit beta type-60101
Proteasome subunit beta type-50203
Carbonic anhydrase 5A, mitochondrial0202
26S proteasome regulatory subunit 70101
Lon protease homolog, mitochondrial0101
Proteasome subunit beta type-100101
Carbonic anhydrase 70202
26S proteasome regulatory subunit 6B0123
26S proteasome non-ATPase regulatory subunit 80101
Proteasome subunit beta type-30101
Proteasome subunit beta type-20102
26S proteasome non-ATPase regulatory subunit 70101
26S proteasome non-ATPase regulatory subunit 40101
26S proteasome complex subunit SEM10101
Proteasome subunit alpha type-60101
26S proteasome regulatory subunit 40101
26S proteasome regulatory subunit 80101
26S proteasome regulatory subunit 10B0101
Beta-carbonic anhydrase 10101
Nuclear factor NF-kappa-B p100 subunit 0101
Transcription factor p650101
26S proteasome non-ATPase regulatory subunit 20101
Histone deacetylase 10202
26S proteasome non-ATPase regulatory subunit 60101
Proteasomal ubiquitin receptor ADRM10101
Carbonic anhydrase 90404
ATP-dependent Clp protease proteolytic subunit0112
Carbonic anhydrase 130101
NACHT, LRR and PYD domains-containing protein 3 0101
Proteasome subunit alpha-type 80101
Histone deacetylase 20202
ATPase family AAA domain-containing protein 59009
Proteasome subunit beta type-70101
26S proteasome non-ATPase regulatory subunit 10101
Ataxin-2100010
Carbonic anhydrase 150303
Histone deacetylase 80202
Histone deacetylase 60202
Carbonic anhydrase 140202
26S proteasome non-ATPase regulatory subunit 130101
Carbonic anhydrase 5B, mitochondrial0202
aldehyde dehydrogenase 1 family, member A19009
thyroid stimulating hormone receptor7007
Nuclear receptor ROR-gamma2002
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, 2-oxoglutarate Oxygenase6006
Chain A, Ferritin light chain4004
Chain A, Cruzipain2002
DNA topoisomerase 0101
15-lipoxygenase, partial5005
ATAD5 protein, partial4004
NFKB1 protein, partial1001
thyroid stimulating hormone receptor5005
regulator of G-protein signaling 42002
67.9K protein8008
glucocerebrosidase1001
putative alpha-glucosidase1001
alpha-galactosidase2002
euchromatic histone-lysine N-methyltransferase 2100010
Bloom syndrome protein isoform 15005
lysosomal alpha-glucosidase preproprotein2002
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta3003
cellular tumor antigen p53 isoform a2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
chromobox protein homolog 1110011
nuclear factor erythroid 2-related factor 2 isoform 27007
huntingtin isoform 25005
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
serine/threonine-protein kinase mTOR isoform 13003
DNA polymerase iota isoform a (long)7007
nuclear receptor ROR-gamma isoform 14004
geminin120012
survival motor neuron protein isoform d7007
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 15005
relaxin receptor 1 isoform 11001
lamin isoform A-delta10110011
Gamma-aminobutyric acid receptor subunit pi4004
Telomerase reverse transcriptase0101
Serine/threonine-protein kinase Chk10134
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
DNA ligase0101
Integrin beta-32002
Integrin alpha-IIb2002
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 103313
DNA topoisomerase 2-alpha03311
Gamma-aminobutyric acid receptor subunit beta-14004
Gamma-aminobutyric acid receptor subunit delta4004
Gamma-aminobutyric acid receptor subunit gamma-24004
Gamma-aminobutyric acid receptor subunit alpha-54004
Gamma-aminobutyric acid receptor subunit alpha-34004
Gamma-aminobutyric acid receptor subunit gamma-14004
Gamma-aminobutyric acid receptor subunit alpha-24004
Type-2 restriction enzyme BamHI0101
Gamma-aminobutyric acid receptor subunit alpha-44004
Gamma-aminobutyric acid receptor subunit gamma-34004
Gamma-aminobutyric acid receptor subunit alpha-64004
Somatostatin receptor type 10202
Somatostatin receptor type 20202
Somatostatin receptor type 40202
Somatostatin receptor type 30202
Somatostatin receptor type 50202
5-hydroxytryptamine receptor 2B0202
Type-2 restriction enzyme HindIII0101
D(1A) dopamine receptor2002
Histone deacetylase 40101
Ribonuclease pancreatic0101
Gamma-aminobutyric acid receptor subunit alpha-14004
Gamma-aminobutyric acid receptor subunit beta-34004
Gamma-aminobutyric acid receptor subunit beta-24004
Inositol monophosphatase 12002
DNA topoisomerase 2-beta02312
DNA topoisomerase 10203
DNA topoisomerase 10101
Integrase 0202
Histone deacetylase 70101
GABA theta subunit4004
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Gamma-aminobutyric acid receptor subunit epsilon4004
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 90101
Histone deacetylase 50101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
acetylcholinesterase6006
phosphopantetheinyl transferase5005
G5005
cytochrome P450 2D66006
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase kappa isoform 14004
HLA class I histocompatibility antigen, B alpha chain 5005
Inositol hexakisphosphate kinase 15005
cytochrome P450 2C9, partial5005
endonuclease IV3003
GLI family zinc finger 3140014
arylsulfatase A2002
thyroid hormone receptor beta isoform a4004
muscarinic acetylcholine receptor M11001
Bile salt export pump0404
Glutathione reductase, mitochondrial0101
Alpha-synuclein1001
Glutathione reductase0101
glp-1 receptor, partial5005
USP1 protein, partial5005
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0303
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0303
nuclear receptor coactivator 3 isoform a0303
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0101
Thymidine kinase0101
Thymidylate synthase0304
Cytochrome P450 3A4010012
Thymidine kinase0101
Deoxycytidine kinase0023
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
interleukin 83003
hypoxia-inducible factor 1 alpha subunit7007
activating transcription factor 63003
Matrix metalloproteinase-90101
Isocitrate lyase0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Microtubule-associated protein tau4004
RAD510101
aryl hydrocarbon receptor4004
v-jun sarcoma virus 17 oncogene homolog (avian)4004
caspase-1 isoform alpha precursor2002
ATP-dependent translocase ABCB10406
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-72002
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20224
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Serum paraoxonase/arylesterase 10303
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20101
Genome polyprotein 0101
Tyrosine-protein kinase Fyn0123
UDP-glucuronosyltransferase 2B70001
SMAD family member 22002
SMAD family member 32002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Regulatory protein E20011
ATP-dependent translocase ABCB10303
Cytochrome P450 2C9 0203
Polyunsaturated fatty acid lipoxygenase ALOX150202
DNA topoisomerase 20001
ATP-dependent translocase ABCB10303
UDP-glucuronosyltransferase 1A1 0102
Glutamate receptor ionotropic, NMDA 1 0203
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0203
Glutamate receptor ionotropic, NMDA 2B0204
Glutamate receptor ionotropic, NMDA 2C0204
DNA topoisomerase 2-alpha 0001
Glutamate receptor ionotropic, NMDA 2D0203
Tubulin beta-2B chain0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Glutamate receptor ionotropic, NMDA 3B0203
Solute carrier organic anion transporter family member 1B30203
Glutamate receptor ionotropic, NMDA 3A0203
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase4004
Skn7p0001
pregnane X receptor2002
nonstructural protein 13003
IDH14004
flap endonuclease 12002
Vpr2002
Solute carrier family 22 member 80001
Epidermal growth factor receptor0224
Amyloid-beta precursor protein1001
Aromatase0505
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Albumin0112
Albumin0011
Cytochrome P450 1A20303
Cytochrome P450 2D60303
Sodium-dependent dopamine transporter0101
Sodium-dependent serotonin transporter0202
Cytochrome P450 2C190202
Smoothened homolog0112
Potassium voltage-gated channel subfamily H member 20303
Sonic hedgehog protein0102
Sonic hedgehog protein0101
Smoothened homolog0224
Broad substrate specificity ATP-binding cassette transporter ABCG20304
Carbonic anhydrase0101
Chain A, Beta-lactamase2002
GALC protein4004
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
DNA repair and recombination protein RadA0011
Cyclin-dependent kinase 10123
Heat shock protein HSP 90-alpha0011
G2/mitotic-specific cyclin-B10101
Indoleamine 2,3-dioxygenase 10213
Cyclin-A20101
Cyclin-dependent kinase 20235
Nitric oxide synthase, brain0101
RAC-alpha serine/threonine-protein kinase0224
Cyclin-A10101
Chain A, Acetylcholinesterase0101
interferon gamma precursor0001
Solute carrier family 22 member 20202
Solute carrier family 22 member 1 0303
Solute carrier family 22 member 30101
Interstitial collagenase0101
Acetylcholinesterase0101
Muscarinic acetylcholine receptor M40202
Alpha-2C adrenergic receptor0202
Acetylcholinesterase0505
Liver carboxylesterase 10001
Multidrug and toxin extrusion protein 20202
Multidrug and toxin extrusion protein 10202
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Beta-lactamase0101
Steroid 17-alpha-hydroxylase/17,20 lyase0303
Epoxide hydrolase 10001
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Alpha-2A adrenergic receptor0202
Cytochrome P450 2C80202
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
5-hydroxytryptamine receptor 2A0202
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0303
Cytochrome P450 11B1, mitochondrial0202
Alpha-2B adrenergic receptor0202
Cytochrome P450 7A1 0101
Cytochrome P450 11B2, mitochondrial0202
Estrogen receptor0102
Substance-K receptor0202
Sodium-dependent noradrenaline transporter 0202
Thromboxane-A synthase 0101
Histamine H2 receptor0202
Gonadotropin-releasing hormone receptor0314
Sodium-dependent serotonin transporter0202
Type-1 angiotensin II receptor0101
Malate dehydrogenase, cytoplasmic0101
Delta-type opioid receptor0202
Cytochrome P450 4F20101
Sodium-dependent dopamine transporter 0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Lanosterol 14-alpha demethylase0213
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Gonadotropin-releasing hormone receptor0101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
Smad31001
Type-1A angiotensin II receptor 0101
Type-1B angiotensin II receptor0202
Type-2 angiotensin II receptor0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
5-hydroxytryptamine receptor 1A0101
Type-1 angiotensin II receptor0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX122002
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
DNA polymerase beta1001
snurportin-11001
DNA polymerase eta isoform 11001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10347
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 432002
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
bromodomain adjacent to zinc finger domain 2B1001
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Androgen receptor0202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nuclear receptor subfamily 1 group I member 20011
Cytochrome P450 11B1, mitochondrial0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Cytochrome P450 2A60101
Cytochrome P450 2A50101
Leukotriene C4 synthase0022
tyrosine-protein kinase Yes3003
Bone morphogenetic protein receptor type-1B0022
Membrane-associated progesterone receptor component 10022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0123
Serine/threonine-protein kinase PLK40123
Serine/threonine-protein kinase 250022
ATP-dependent RNA helicase DDX3X0022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0022
Pyridoxal kinase0022
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase RIO30022
Dual specificity mitogen-activated protein kinase kinase 70022
Inhibitor of nuclear factor kappa-B kinase subunit beta0023
Peripheral plasma membrane protein CASK0022
Aurora kinase A0123
Cyclin-G-associated kinase0022
Serine/threonine-protein kinase DCLK10022
Inhibitor of nuclear factor kappa-B kinase subunit alpha0022
Muscle, skeletal receptor tyrosine-protein kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Mitogen-activated protein kinase 130022
3-phosphoinositide-dependent protein kinase 10022
Mitogen-activated protein kinase kinase kinase 130022
Death-associated protein kinase 30022
Mitogen-activated protein kinase kinase kinase 70022
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
NUAK family SNF1-like kinase 10123
Dynamin-like 120 kDa protein, mitochondrial0022
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0022
Tyrosine-protein kinase JAK20022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0022
Serine/threonine-protein kinase PAK 30022
Cyclin-dependent kinase-like 50022
Serine/threonine-protein kinase 17B0022
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30022
Cyclin-dependent kinase 140022
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Serine/threonine-protein kinase OSR10022
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40224
Serine/threonine-protein kinase Chk20123
RAF proto-oncogene serine/threonine-protein kinase0123
Receptor tyrosine-protein kinase erbB-20022
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20022
ADP/ATP translocase 20022
Protein kinase C beta type0022
Insulin receptor0123
Tyrosine-protein kinase Lck0123
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Macrophage colony-stimulating factor 1 receptor0224
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0123
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0123
Tyrosine-protein kinase HCK0123
Proto-oncogene tyrosine-protein kinase ROS0022
Platelet-derived growth factor receptor beta0426
Tyrosine-protein kinase Fgr0022
Wee1-like protein kinase 20022
Uncharacterized serine/threonine-protein kinase SBK30022
Serine/threonine-protein kinase A-Raf0022
Mast/stem cell growth factor receptor Kit0426
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0033
Serine/threonine-protein kinase pim-10022
Fibroblast growth factor receptor 10224
Myosin light chain kinase, smooth muscle0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20022
Proto-oncogene tyrosine-protein kinase Src0123
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Insulin receptor-related protein0022
Serine/threonine-protein kinase B-raf0022
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Platelet-derived growth factor receptor alpha0325
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0022
cAMP-dependent protein kinase catalytic subunit alpha0022
Vascular endothelial growth factor receptor 1 0325
General transcription and DNA repair factor IIH helicase subunit XPD0022
Interferon-induced, double-stranded RNA-activated protein kinase0022
Casein kinase II subunit alpha'0022
Serine/threonine-protein kinase MAK0022
Cyclin-dependent kinase 11B0022
Ephrin type-A receptor 10022
Fibroblast growth factor receptor 20123
Receptor tyrosine-protein kinase erbB-30022
Multifunctional protein ADE20022
Fibroblast growth factor receptor 40022
Fibroblast growth factor receptor 30022
cAMP-dependent protein kinase catalytic subunit gamma0022
cAMP-dependent protein kinase catalytic subunit beta0022
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
Protein kinase C eta type0022
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Activin receptor type-2A0022
Mitogen-activated protein kinase 3 0022
MAP/microtubule affinity-regulating kinase 30022
Mitogen-activated protein kinase 10022
Ephrin type-A receptor 20022
Ephrin type-A receptor 30022
Ephrin type-A receptor 80022
Ephrin type-B receptor 20022
Leukocyte tyrosine kinase receptor0022
Non-receptor tyrosine-protein kinase TYK20022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0022
Heme oxygenase 20022
Tyrosine-protein kinase receptor UFO0123
Mitogen-activated protein kinase 40022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-beta serine/threonine-protein kinase0022
G protein-coupled receptor kinase 40022
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Prostaglandin G/H synthase 20123
Tyrosine-protein kinase receptor Tie-10022
Vascular endothelial growth factor receptor 30325
Vascular endothelial growth factor receptor 20426
Dual specificity mitogen-activated protein kinase kinase 20022
Receptor-type tyrosine-protein kinase FLT30124
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0123
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0123
Serine/threonine-protein kinase mTOR0123
Megakaryocyte-associated tyrosine-protein kinase0022
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase TXK0022
Tyrosine-protein kinase ABL20123
Tyrosine-protein kinase FRK0022
G protein-coupled receptor kinase 60022
Tyrosine-protein kinase ZAP-700022
Tyrosine-protein kinase SYK0022
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 40022
Dual specificity mitogen-activated protein kinase kinase 30022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0123
Casein kinase I isoform delta0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0123
MAP kinase-activated protein kinase 20022
Cyclin-dependent kinase 80022
Elongation factor Tu, mitochondrial0022
Cysteine--tRNA ligase, cytoplasmic0022
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0022
Glycogen synthase kinase-3 beta0022
Cyclin-dependent kinase 70022
Cyclin-dependent kinase 90022
Ras-related protein Rab-27A0022
Tyrosine-protein kinase Blk0022
Interleukin-1 receptor-associated kinase 10022
Ribosomal protein S6 kinase alpha-30123
Cytoplasmic tyrosine-protein kinase BMX0022
cAMP-dependent protein kinase catalytic subunit PRKX0022
Serine/threonine-protein kinase Nek20123
Serine/threonine-protein kinase Nek30022
Serine/threonine-protein kinase Nek40022
Tyrosine-protein kinase JAK30022
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10224
Death-associated protein kinase 10022
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 120022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10023
5'-AMP-activated protein kinase catalytic subunit alpha-20124
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40123
Ephrin type-B receptor 10022
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Hormonally up-regulated neu tumor-associated kinase0022
Serine/threonine-protein kinase SIK10022
Receptor-interacting serine/threonine-protein kinase 40022
Ras-related protein Rab-100022
Cell division control protein 2 homolog0022
Actin-related protein 30022
Actin-related protein 20022
Calcium-dependent protein kinase 10022
GTP-binding nuclear protein Ran0022
Tubulin alpha-1A chain0022
Casein kinase II subunit alpha0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0022
SRSF protein kinase 20022
Casein kinase I isoform gamma-20022
Mitogen-activated protein kinase kinase kinase 90022
Serine/threonine-protein kinase PknB0022
Cyclin-dependent kinase 30022
Cyclin-dependent kinase-like 10022
Cyclin-dependent kinase 60022
Cyclin-dependent-like kinase 5 0022
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
ATP-dependent 6-phosphofructokinase, platelet type0022
Protein kinase C epsilon type0022
Dual specificity mitogen-activated protein kinase kinase 10022
Angiopoietin-1 receptor0123
Mitogen-activated protein kinase kinase kinase 100022
Protein kinase C theta type0022
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10123
Protein kinase C delta type0022
Tyrosine-protein kinase BTK0022
Tyrosine-protein kinase receptor TYRO30022
Cyclin-dependent kinase 180022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Tyrosine-protein kinase ITK/TSK0022
Myotonin-protein kinase0022
Mitogen-activated protein kinase kinase kinase kinase 20022
Mitogen-activated protein kinase kinase kinase 120022
Tyrosine-protein kinase Mer0022
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10124
Serine/threonine-protein kinase PAK 10022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
cGMP-dependent protein kinase 20022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Serine/threonine-protein kinase PRP4 homolog0022
Receptor-interacting serine/threonine-protein kinase 10123
Calcium/calmodulin-dependent protein kinase type II subunit beta0022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0022
Cyclin-dependent kinase 130022
Calcium/calmodulin-dependent protein kinase type 10022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Serine/threonine-protein kinase D10022
Serine/threonine-protein kinase 380022
Receptor tyrosine-protein kinase erbB-40022
Ribosomal protein S6 kinase alpha-20022
Ephrin type-A receptor 70022
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10123
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0022
Mitogen-activated protein kinase 110022
Serine/threonine-protein kinase STK110022
Rhodopsin kinase GRK10022
NT-3 growth factor receptor0022
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140022
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
BDNF/NT-3 growth factors receptor0022
Mitogen-activated protein kinase 60022
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0022
AP2-associated protein kinase 10123
Myosin light chain kinase 30022
Receptor protein-tyrosine kinase 0101
Serine/threonine-protein kinase SBK10022
Mitogen-activated protein kinase kinase kinase 190022
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase TNNI3K0022
Rab-like protein 30022
Leucine-rich repeat serine/threonine-protein kinase 20123
Serine/threonine-protein kinase MRCK alpha0022
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase Nek50022
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30022
Dual serine/threonine and tyrosine protein kinase0022
Mitogen-activated protein kinase kinase kinase 150022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
Serine/threonine-protein kinase tousled-like 20022
Serine/threonine-protein kinase 32C0022
Serine/threonine-protein kinase pim-30022
ATP-dependent RNA helicase DDX420022
Serine/threonine-protein kinase VRK20022
Myosin light chain kinase family member 40022
Homeodomain-interacting protein kinase 10022
Calcium/calmodulin-dependent protein kinase type 1D0022
Mitogen-activated protein kinase kinase kinase kinase 30022
Cyclin-dependent kinase-like 30022
MAP kinase-activated protein kinase 50022
Serine/threonine-protein kinase BRSK20022
Serine/threonine-protein kinase NIM10022
Serine/threonine-protein kinase ULK20022
Misshapen-like kinase 10022
Serine/threonine-protein kinase DCLK20022
Calcium/calmodulin-dependent protein kinase kinase 10022
Casein kinase I isoform alpha-like0022
Homeodomain-interacting protein kinase 40022
Myosin-IIIa0022
Ankyrin repeat and protein kinase domain-containing protein 10022
Serine/threonine-protein kinase Nek110022
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase BRSK10022
Serine/threonine-protein kinase 350022
Serine/threonine-protein kinase Nek70022
Rhodopsin kinase GRK70022
Serine/threonine-protein kinase 32A0022
Myosin-IIIb0022
ATP-dependent RNA helicase DDX10022
Dual specificity tyrosine-phosphorylation-regulated kinase 20022
Cyclin-dependent kinase-like 20022
Mitogen-activated protein kinase kinase kinase kinase 10022
Serine/threonine-protein kinase Sgk30022
Atypical kinase COQ8B, mitochondrial0022
Aurora kinase B0123
MAP/microtubule affinity-regulating kinase 40022
Calcium/calmodulin-dependent protein kinase type 1G0022
Serine/threonine-protein kinase Nek10022
Cyclin-dependent kinase 150022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
SRSF protein kinase 10022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0022
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Serine/threonine-protein kinase RIO10022
MAP kinase-interacting serine/threonine-protein kinase 10022
Serine/threonine-protein kinase RIO20022
Cyclin-dependent kinase 190022
Transient receptor potential cation channel subfamily M member 60022
Testis-specific serine/threonine-protein kinase 10022
Serine/threonine-protein kinase 330022
Nucleolar GTP-binding protein 10022
Serine/threonine-protein kinase D20022
Serine/threonine-protein kinase DCLK30022
NUAK family SNF1-like kinase 20022
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
Myosin light chain kinase 2, skeletal/cardiac muscle0022
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
Homeodomain-interacting protein kinase 20022
Tyrosine-protein kinase Srms0022
Homeodomain-interacting protein kinase 30022
Serine/threonine-protein kinase PLK30123
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
MAP kinase-interacting serine/threonine-protein kinase 20022
Serine/threonine-protein kinase Nek60022
Casein kinase I isoform gamma-10022
Serine/threonine-protein kinase PAK 60123
SNF-related serine/threonine-protein kinase0022
Serine/threonine-protein kinase LATS20022
Serine/threonine-protein kinase 360022
Phenylalanine--tRNA ligase beta subunit0022
Isoleucine--tRNA ligase, mitochondrial0022
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Serine/threonine-protein kinase 32B0022
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120022
Serine/threonine-protein kinase PLK20123
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130022
Serine/threonine-protein kinase MARK10022
Serine/threonine-protein kinase pim-20022
Serine/threonine-protein kinase PAK 50123
Serine/threonine-protein kinase 260022
eIF-2-alpha kinase GCN20022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Serine/threonine-protein kinase NLK0022
Phosphatidylinositol 4-kinase beta0022
Serine/threonine-protein kinase 17A0022
STE20/SPS1-related proline-alanine-rich protein kinase0022
Ephrin type-A receptor 60022
5'-AMP-activated protein kinase subunit gamma-20023
Serine/threonine-protein kinase TBK10123
Septin-90022
Death-associated protein kinase 20022
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase tousled-like 10022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50022
ALK tyrosine kinase receptor0123
SRSF protein kinase 30022
Serine/threonine-protein kinase ICK0022
Cyclin-dependent kinase 11A0022
Aurora kinase C0022
Calcium/calmodulin-dependent protein kinase type II subunit alpha0022
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase 38-like0022
Microtubule-associated serine/threonine-protein kinase 10022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Serine/threonine-protein kinase 240022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Muscarinic acetylcholine receptor M10011
Muscarinic acetylcholine receptor M30011
Muscarinic acetylcholine receptor M40011
Muscarinic acetylcholine receptor M50011
Muscarinic acetylcholine receptor M20011
Muscarinic acetylcholine receptor M10012
Cytochrome P450 2B60202
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0001
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Muscarinic acetylcholine receptor M50012
Sigma non-opioid intracellular receptor 10101
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
Sigma non-opioid intracellular receptor 10202
beta-2 adrenergic receptor1001
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
heat shock protein HSP 90-alpha isoform 20001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histamine H2 receptor1001
Guanine nucleotide-binding protein G1001
heat shock protein 90, putative0001
chaperonin-containing TCP-1 beta subunit homolog1001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit beta-10001
Cell division cycle 7-related protein kinase0011
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Eukaryotic translation initiation factor 5B0011
Proto-oncogene tyrosine-protein kinase Src0101
Mast/stem cell growth factor receptor Kit0101
Platelet-derived growth factor receptor beta0101
Adenine phosphoribosyltransferase0011
Potassium voltage-gated channel subfamily E member 10101
Ras-related protein Rab-6A0011
Beta-adrenergic receptor kinase 10101
Platelet-derived growth factor receptor alpha 0101
UMP-CMP kinase 0011
Bifunctional epoxide hydrolase 20101
G protein-coupled receptor kinase 50101
Myosin-100011
Electron transfer flavoprotein subunit beta0011
Choline-phosphate cytidylyltransferase A0011
Potassium voltage-gated channel subfamily KQT member 10101
DNA-dependent protein kinase catalytic subunit0101
Protein delta homolog 10112
Mu-type opioid receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Protein kinase C zeta type0011
Serine/threonine-protein kinase ATR0011
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
Cyclin-dependent kinase 100011
Uncharacterized aarF domain-containing protein kinase 50011
Serine/threonine-protein kinase ULK30011
NAD-dependent protein deacetylase sirtuin-20101
PAS domain-containing serine/threonine-protein kinase0011
Poly [ADP-ribose] polymerase tankyrase-20011
Bromodomain-containing protein 90011
Serine/threonine-protein kinase 30011
Bromodomain-containing protein 70011
Potassium voltage-gated channel subfamily D member 30101
Thyroid hormone receptor-associated protein 30011
polyadenylate-binding protein 10101
serine/threonine-protein kinase PLK11001
Cytochrome P450 2B10101
NPYLR7B0011
Hypoxia-inducible factor 1-alpha0112
Endothelial PAS domain-containing protein 10011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]