Page last updated: 2024-09-28

Equine Infectious Anemia

Viral disease of horses caused by the equine infectious anemia virus (EIAV; INFECTIOUS ANEMIA VIRUS, EQUINE). It is characterized by intermittent fever, weakness, and anemia. Chronic infection consists of acute episodes with remissions.

Synonyms(2)

Synonym
Swamp Fever
Equine Infectious Anemia

Research Excerpts

Research

Studies (44)

TimeframeStudies, This Condition (%)All Conditions %
pre-199019 (43.18)23.3326
1990's4 (9.09)12.5806
2000's9 (20.45)18.1394
2010's9 (20.45)28.8240
2020's3 (6.82)9.53
DrugIndicatedRelationship StrengthStudiesTrials
phytic acid0low10
nitrites0low10
phenol0low10
erythrosine0low10
chloramphenicol0low10
edetic acid0low10
sodium citrate, anhydrous0low10
asparagine0low10
tryptophan0low10
arginine0low10
thiazoles0low10
pyrazines0low10
hematoxylin0low10
malondialdehyde0low10
eosine yellowish-(ys)0low10
mesterolone0low10
deuterium oxide0low10
ammonium chloride0low10
tetradecanoylphorbol acetate0low10
cadmium telluride0low10
tripalmitoyl cysteine0low10
atropine0low10
sodium dodecyl sulfate0low10
bilirubin0low10
cysteine0low10
ammonium sulfate0low10
tellurium0low10
thiazole orange0low10
sepharose0low10
oligonucleotides0low10
transforming growth factor beta0low10
agar0low70

Protein Targets (381)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase3003
phosphopantetheinyl transferase5005
NFKB1 protein, partial1001
GLS protein3003
thyroid stimulating hormone receptor3003
alpha-galactosidase3003
euchromatic histone-lysine N-methyltransferase 25005
cytochrome P450 2C19 precursor1001
chromobox protein homolog 12002
flap endonuclease 13003
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M11001
lethal factor (plasmid)3003
Cytochrome P450 3A40102
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase4004
Carbonic anhydrase 10305
Carbonic anhydrase 20406
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Carbonic anhydrase-like protein, putative0002
Amino acid transporter0101
Chain A, 2-oxoglutarate Oxygenase4004
GLI family zinc finger 35005
AR protein6006
nuclear receptor subfamily 1, group I, member 32002
glucocorticoid receptor [Homo sapiens]2002
retinoid X nuclear receptor alpha4004
pregnane X nuclear receptor3003
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0101
ATP-binding cassette sub-family C member 30202
Multidrug resistance-associated protein 40202
5-hydroxytryptamine receptor 40202
Bile salt export pump0202
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M10215
Muscarinic acetylcholine receptor M30215
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M10216
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30215
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor2003
5-hydroxytryptamine receptor 70101
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
Canalicular multispecific organic anion transporter 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, Cruzipain2002
USP1 protein, partial3003
Microtubule-associated protein tau4004
aldehyde dehydrogenase 1 family, member A13003
vitamin D3 receptor isoform VDRA4004
DNA polymerase kappa isoform 14004
caspase-1 isoform alpha precursor1001
lamin isoform A-delta103003
Caspase-71001
Inositol monophosphatase 12002
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10203
interleukin 82002
TDP1 protein3003
EWS/FLI fusion protein1001
retinoic acid nuclear receptor alpha variant 16006
estrogen-related nuclear receptor alpha6006
farnesoid X nuclear receptor3003
estrogen nuclear receptor alpha5005
G3003
cytochrome P450 2D63003
peroxisome proliferator activated receptor gamma4004
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
aryl hydrocarbon receptor3003
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
thyroid hormone receptor beta isoform 24004
heat shock protein beta-11001
nuclear factor erythroid 2-related factor 2 isoform 14004
geminin3003
streptokinase A precursor0011
Dihydroxyacetone phosphate acyltransferase0001
Interferon beta3003
HLA class I histocompatibility antigen, B alpha chain 3003
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
Cellular tumor antigen p534004
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Inositol hexakisphosphate kinase 13003
Methionine--tRNA ligase, mitochondrial0011
cytochrome P450 2C9, partial3003
hypoxia-inducible factor 1 alpha subunit2002
RAR-related orphan receptor gamma4004
progesterone receptor1001
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Histone H2A.x2002
Eyes absent homolog 20101
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Voltage-dependent calcium channel gamma-2 subunit2002
Amyloid-beta precursor protein0101
Angiotensin-converting enzyme 0101
Glutamate receptor 22002
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Chain A, Beta-lactamase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Genome polyprotein 0112
Luciferase3003
acetylcholinesterase1001
chaperonin-containing TCP-1 beta subunit homolog1001
SMAD family member 22002
ATAD5 protein, partial1001
Fumarate hydratase1001
SMAD family member 32002
thioredoxin glutathione reductase3003
hypothetical protein, conserved2002
cytochrome P450 family 3 subfamily A polypeptide 42002
polyprotein1001
bromodomain adjacent to zinc finger domain 2B3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a3003
thyroid stimulating hormone receptor3003
thyrotropin-releasing hormone receptor1001
Bloom syndrome protein isoform 12002
thyroid hormone receptor beta isoform a2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
eyes absent homolog 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I2002
histone acetyltransferase KAT2A isoform 13003
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0202
Chain E, Fibrin beta chain0101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, RNA-directed RNA polymerase NS50101
15-lipoxygenase, partial1001
WRN1001
Mcl-10101
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
PPM1D protein1001
alkaline phosphatase, intestinal0011
apical membrane antigen 1, AMA11001
regulator of G-protein signaling 41001
67.9K protein1001
glucocerebrosidase1001
luciferase1001
pyruvate kinase1001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
CDK50001
serine-protein kinase ATM isoform a1001
lysosomal alpha-glucosidase preproprotein1001
major prion protein preproprotein Prp precursor0101
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0011
cellular tumor antigen p53 isoform a1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
glucose-6-phosphate 1-dehydrogenase isoform b0101
intestinal alkaline phosphatase precursor0011
nuclear factor erythroid 2-related factor 2 isoform 21001
mitogen-activated protein kinase 12002
serine/threonine-protein kinase PLK11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
nuclear receptor ROR-gamma isoform 12002
Vif0101
Tat0101
survival motor neuron protein isoform d1001
cytochrome P450 3A4 isoform 11001
DNA dC->dU-editing enzyme APOBEC-3G isoform 10101
alkaline phosphatase, germ cell type preproprotein0011
endoribonuclease toxin MazF0011
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Gamma-aminobutyric acid receptor subunit pi1001
Rap guanine nucleotide exchange factor 31001
Integrin beta-31001
Integrin alpha-IIb1001
Pyruvate kinase PKM0101
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Endothelin receptor type B1001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
Endothelin-1 receptor1001
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
GABA theta subunit1001
Gamma-aminobutyric acid receptor subunit epsilon1001
phosphoglycerate kinase1001
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
Sex hormone-binding globulin0011
Androgen receptor0101
Carbonic anhydrase 40304
Carbonic anhydrase0102
Carbonic anhydrase 150203
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Penicillin Amidohydrolase0101
Chain B, Penicillin Amidohydrolase0101
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Lysozyme0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
peroxisome proliferator-activated receptor delta2002
Polyphenol oxidase 20001
Carbonic anhydrase 120102
Endolysin0011
Carbonic anhydrase 30102
Gamma-aminobutyric acid receptor subunit alpha-10011
Sulfotransferase 1A1 0001
Gamma-aminobutyric acid receptor subunit gamma-20011
Cannabinoid receptor 10101
Carbonic anhydrase 60203
Adenosine receptor A10101
Adenosine receptor A2a0101
Carbonic anhydrase 5A, mitochondrial0203
Carbonic anhydrase 70102
Gamma-aminobutyric acid receptor subunit beta-20011
Spike glycoprotein3003
Carbonic anhydrase 0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 90203
Carbonic anhydrase0101
Carbonic anhydrase 0102
Carbonic anhydrase 30202
Carbonic anhydrase0203
Carbonic anhydrase 130101
Carbonic anhydrase 130102
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
Bifunctional epoxide hydrolase 20101
Peroxisome proliferator-activated receptor alpha1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
Serine/threonine-protein kinase D30011
Protein kinase C gamma type0112
Protein kinase C beta type0112
Luciferin 4-monooxygenase0011
Protein kinase C alpha type0112
Beta-1 adrenergic receptor0101
Protein kinase C eta type0011
Protein kinase C iota type0011
Protein kinase C epsilon type0112
Protein kinase C theta type0011
Protein kinase C zeta type0011
Protein kinase C delta type0112
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
arylsulfatase A1001
peripheral myelin protein 22 isoform 11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
M-phase phosphoprotein 81001
Dihydrofolate reductase0202
Plasma kallikrein0001
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Stromelysin-10101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Glutamate receptor ionotropic, NMDA 1 0001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Glutamate receptor ionotropic, NMDA 3A0001
Phospholipase A-2-activating protein0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]