Page last updated: 2024-09-28

Epidermolysis Bullosa Junctionalis, Disentis Type

Synonyms(15)

Synonym
Epidermolysis Bullosa, Junctional, Herlitz Type
Herlitz-Pearson-Type Epidermolysis Bullosa
Herlitz-Pearson Type Epidermolysis Bullosa
Junctional Epidermolysis Bullosa
Epidermolysis Bullosa, Junctional, Herlitz-Pearson Type
Herlitz's Disease
Epidermolysis Bullosa Letalis
Epidermolysis Bullosa Junctionalis, Severe Nonlethal
Epidermolysis Bullosa Junctionalis, Herlitz Type
Epidermolysis Bullosa Junctionalis, Disentis Type
Epidermolysis Bullosa Progressiva
Epidermolysis Bullosa Junctionalis, Progressive
Epidermolysis Bullosa, Generalized Atrophic Benign
Lethal Junctional Epidermolysis Bullosa
Herlitz Disease

Research Excerpts

Overview

ExcerptReference
"Junctional epidermolysis bullosa is a heterogeneous autosomal recessively inherited blistering skin disorder associated with fragility at the dermal-epidermal junction."( Christiano, AM; Dunnill, MG; Eady, RA; Gatalica, B; Li, K; McGrath, JA; McMillan, JR; Uitto, J, 1996)
"Junctional epidermolysis bullosa is a group of hereditary bullous disorders resulting from defects in several hemidesmosome-anchoring filament components."( Eady, RA; McGrath, JA; McMillan, JR; Tidman, MJ, 1998)

Treatment

ExcerptReference
"Severe generalized junctional epidermolysis bullosa, a lethal hereditary blistering disorder, is usually treated by palliative care."( Bruckner-Tuderman, L; Hammersen, J; Has, C; Kiritsi, D; Metzler, M; Naumann-Bartsch, N; Schneider, H; Söder, S; Stachel, D; Tardieu, M, 2016)

Research

Studies (138)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (0.72)23.3326
1990's49 (35.51)12.5806
2000's33 (23.91)18.1394
2010's40 (28.99)28.8240
2020's15 (10.87)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
salicylic acid0low10
glycine0low20
fentanyl0low10
flumazenil0low10
gabapentin0low10
gentamicin0medium62
lidocaine0low10
qx-3140low10
losartan0low10
prednisolone0low10
tyrosine0low20
cycloheximide0low10
gentian violet0low10
vancomycin0low10
carbonates0low10
silver0low10
tridemorph0medium1122
glutamic acid0low10
timolol0low10
delphinidin0low10
artesunic acid0low10
atazanavir sulfate0low10
cortisone0low10
mycophenolic acid0low10
bromochloroacetic acid0low50
morphine0low10
silicon0low10
tetrodotoxin0low10
involucrin0low10
oxadiazoles0low10
ptc 1240low10
trametinib0low10

Protein Targets (917)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
thioredoxin reductase9009
USP1 protein, partial4004
NFKB1 protein, partial2002
GLS protein4004
cytochrome P450 family 3 subfamily A polypeptide 46006
cytochrome P450 2D64004
arylsulfatase A5005
cytochrome P450 2D6 isoform 13003
D(1A) dopamine receptor2002
chromobox protein homolog 15005
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 11001
nuclear factor erythroid 2-related factor 2 isoform 17007
muscarinic acetylcholine receptor M17007
Solute carrier family 22 member 1 0405
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40505
Voltage-dependent L-type calcium channel subunit alpha-1F0101
5-hydroxytryptamine receptor 40202
Bile salt export pump011011
Albumin0011
High affinity nerve growth factor receptor0134
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M40404
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
5-hydroxytryptamine receptor 2C0101
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M50404
Alpha-2A adrenergic receptor0516
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10404
Angiotensin-converting enzyme0202
D(2) dopamine receptor0505
5-hydroxytryptamine receptor 2A0101
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
5-hydroxytryptamine receptor 1A0617
Muscarinic acetylcholine receptor M30404
D(1A) dopamine receptor0404
D(1B) dopamine receptor0101
UDP-glucuronosyltransferase 1A40102
Sodium-dependent noradrenaline transporter 0202
Histamine H2 receptor0404
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0404
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0101
5-hydroxytryptamine receptor 60101
Histamine H1 receptor0101
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
Histamine H1 receptor0303
D(3) dopamine receptor0505
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0202
UDP-glucuronosyltransferase 1A30002
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0404
Histamine H2 receptor3105
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
5-hydroxytryptamine receptor 70202
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Sodium-dependent dopamine transporter 0404
Potassium voltage-gated channel subfamily H member 20505
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0303
Sigma non-opioid intracellular receptor 10213
5-hydroxytryptamine receptor 4 0101
Nuclear receptor subfamily 3 group C member 3 0202
Canalicular multispecific organic anion transporter 10505
Sodium channel protein type 2 subunit alpha0101
Ataxin-26006
Sigma non-opioid intracellular receptor 10505
5-hydroxytryptamine receptor 3B0101
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0101
RAR-related orphan receptor gamma8008
AR protein120012
aldehyde dehydrogenase 1 family, member A18008
nuclear receptor subfamily 1, group I, member 36006
retinoic acid nuclear receptor alpha variant 16006
thyroid stimulating hormone receptor2002
Cellular tumor antigen p536006
Nuclear receptor ROR-gamma3003
Carbonic anhydrase 10305
Carbonic anhydrase 20305
Carbonic anhydrase 40203
Carbonic anhydrase0102
Carbonic anhydrase 150203
endonuclease IV2002
dopamine D1 receptor1001
pregnane X receptor3003
TDP1 protein120012
GLI family zinc finger 36006
progesterone receptor6006
regulator of G-protein signaling 46006
glucocorticoid receptor [Homo sapiens]7007
retinoid X nuclear receptor alpha7007
pregnane X nuclear receptor5005
estrogen nuclear receptor alpha120012
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma7007
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
euchromatic histone-lysine N-methyltransferase 2110011
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)4004
peripheral myelin protein 22 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
heat shock protein beta-12002
flap endonuclease 13003
geminin9009
survival motor neuron protein isoform d7007
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 81001
Gamma-aminobutyric acid receptor subunit pi75113
Glucocorticoid receptor04110
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0202
Gamma-aminobutyric acid receptor subunit beta-175113
Gamma-aminobutyric acid receptor subunit delta75113
Gamma-aminobutyric acid receptor subunit gamma-275214
Gamma-aminobutyric acid receptor subunit alpha-575113
Gamma-aminobutyric acid receptor subunit alpha-375113
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Gamma-aminobutyric acid receptor subunit gamma-175113
Gamma-aminobutyric acid receptor subunit alpha-275113
Glycine receptor subunit alpha-30404
Gamma-aminobutyric acid receptor subunit alpha-475113
Gamma-aminobutyric acid receptor subunit gamma-375113
Gamma-aminobutyric acid receptor subunit alpha-675113
Gamma-aminobutyric acid receptor subunit alpha-175214
Gamma-aminobutyric acid receptor subunit beta-375113
Gamma-aminobutyric acid receptor subunit beta-275214
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 435005
GABA theta subunit75113
Multidrug and toxin extrusion protein 10303
Gamma-aminobutyric acid receptor subunit epsilon75113
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
interleukin 81001
glp-1 receptor, partial3003
ATAD5 protein, partial2002
Fumarate hydratase2002
PPM1D protein1001
Smad31001
estrogen receptor 2 (ER beta)4004
EWS/FLI fusion protein5005
estrogen-related nuclear receptor alpha5005
farnesoid X nuclear receptor3003
polyprotein2002
67.9K protein3003
P531001
RPL19A0011
IDH12002
aryl hydrocarbon receptor5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
activating transcription factor 64004
Histone H2A.x3003
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a2002
thyroid hormone receptor beta isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 25005
thyroid hormone receptor beta isoform 24004
nuclear factor NF-kappa-B p105 subunit isoform 12002
ras-related protein Rab-9A1001
heat shock protein HSP 90-alpha isoform 20001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
nuclear receptor ROR-gamma isoform 14004
transactivating tegument protein VP16 [Human herpesvirus 1]0101
COUP transcription factor 2 isoform a0101
lethal factor (plasmid)3003
Transmembrane protease serine 20011
Glucose transporter0101
Voltage-dependent calcium channel gamma-2 subunit5005
Hexose transporter 1 0101
Interferon beta6006
Procathepsin L0011
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Solute carrier family 2, facilitated glucose transporter member 10101
Glutamate receptor 25319
Alpha-synuclein2103
Spike glycoprotein3014
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
ATPase family AAA domain-containing protein 55005
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0011
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
Epidermal growth factor receptor0213
Vascular endothelial growth factor receptor 20101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
CREB-binding protein0101
Luciferase3003
potassium voltage-gated channel subfamily H member 2 isoform d2002
Nuclear receptor subfamily 1 group I member 20011
ATP-dependent translocase ABCB10315
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0304
Delta-type opioid receptor0416
Mu-type opioid receptor0429
Kappa-type opioid receptor0315
Mu-type opioid receptor0629
Delta-type opioid receptor0416
Kappa-type opioid receptor0404
Kappa-type opioid receptor0618
Mu-type opioid receptor0316
Mu-type opioid receptor0404
Sigma non-opioid intracellular receptor 10101
phosphopantetheinyl transferase3003
thyroid stimulating hormone receptor4004
G4004
Bloom syndrome protein isoform 14004
cytochrome P450 2C19 precursor1001
muscleblind-like protein 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Bile salt export pump0202
HLA class I histocompatibility antigen, B alpha chain 4004
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Neuronal acetylcholine receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit alpha-30202
Neuronal acetylcholine receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-10224
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20224
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit beta-30224
Gamma-aminobutyric acid receptor subunit alpha-50224
Gamma-aminobutyric acid receptor subunit alpha-30224
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit epsilon0202
Neuronal acetylcholine receptor subunit alpha-70101
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit gamma-10202
Inositol hexakisphosphate kinase 14004
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
cytochrome P450 2C9, partial4004
thioredoxin glutathione reductase1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
lamin isoform A-delta105005
Voltage-dependent calcium channel subunit alpha-2/delta-10101
ATP-dependent phosphofructokinase3003
Chain A, Ferritin light chain2002
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
bromodomain adjacent to zinc finger domain 2B1001
transcriptional regulator ERG isoform 31001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
peripheral myelin protein 224004
histone acetyltransferase KAT2A isoform 13003
neuropeptide S receptor isoform A1001
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit rho-20011
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit beta-30011
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
Histone deacetylase 10101
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10202
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Platelet glycoprotein VI0124
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase3003
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Cruzipain2002
acetylcholinesterase2002
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
hypoxia-inducible factor 1 alpha subunit2002
SMAD family member 23003
SMAD family member 33003
Microtubule-associated protein tau3004
caspase 7, apoptosis-related cysteine protease1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
alpha synuclein, partial1001
hypothetical protein, conserved1001
glucocerebrosidase1001
luciferase1001
caspase-31001
thyrotropin-releasing hormone receptor1001
nuclear receptor subfamily 1, group I, member 23003
Caspase-71001
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
vitamin D3 receptor isoform VDRA1001
caspase-31001
histone deacetylase 9 isoform 32002
huntingtin isoform 21001
mitogen-activated protein kinase 12002
DNA polymerase kappa isoform 11001
Integrin beta-31012
Tyrosine-protein kinase Fyn0112
Integrin alpha-IIb1012
Cytochrome P450 3A40314
60 kDa chaperonin0101
Adenosine receptor A30202
Cytochrome P450 2D60202
60 kDa heat shock protein, mitochondrial0202
Androgen receptor0303
Alpha-1B adrenergic receptor0303
Substance-K receptor0202
Acetylcholinesterase0202
Glutamate receptor ionotropic, kainate 11214
Adenosine receptor A2a0202
Glutamate receptor ionotropic, kainate 21214
Glutamate receptor ionotropic, kainate 31203
10 kDa heat shock protein, mitochondrial0202
Disintegrin and metalloproteinase domain-containing protein 171001
Fatty-acid amide hydrolase 11102
Inositol monophosphatase 11001
Glutamate receptor ionotropic, kainate 41203
Leukotriene B4 receptor 11001
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
Glutamate receptor ionotropic, kainate 51203
10 kDa chaperonin 0202
Leukotriene B4 receptor 21001
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10314
Glutamate receptor 30314
Glutamate receptor 40314
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0427
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate receptor ionotropic, NMDA 2A 0427
Glutamate receptor ionotropic, NMDA 2B0427
Glutamate receptor ionotropic, NMDA 2C0427
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0427
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0427
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0427
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10202
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Chain A, Beta-lactamase1001
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Neprilysin0101
Cytochrome P450 2C9 0202
Angiotensin-converting enzyme 0101
Atrial natriuretic peptide receptor 30101
Thromboxane A2 receptor 0102
Type-1A angiotensin II receptor 0213
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Type-1B angiotensin II receptor0202
Adenosine receptor A2a0102
Type-1 angiotensin II receptor0215
Type-1 angiotensin II receptor0112
Type-2 angiotensin II receptor0202
Type-2 angiotensin II receptor0101
Squalene synthase0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Solute carrier organic anion transporter family member 1B30202
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Type-1 angiotensin II receptor0112
Solute carrier organic anion transporter family member 1B10202
ATP-dependent translocase ABCB10202
Translocator protein0112
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
ATP-dependent translocase ABCB10202
UDP-glucuronosyltransferase 1A1 0102
UDP-glucuronosyltransferase 2B10 0101
Opioid receptor, delta 1b 0101
Acetylcholinesterase0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Histidine decarboxylase0011
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0303
Kappa-type opioid receptor0214
Nociceptin receptor0101
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0112
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20213
Inosine-5'-monophosphate dehydrogenase 1 0202
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
Flavin reductase (NADPH)0011
15-lipoxygenase, partial1001
cytochrome P450 2C9 precursor1001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20103
Carbonic anhydrase 120102
5'-AMP-activated protein kinase subunit beta-20001
Albumin0112
Polymerase acidic protein0011
Carbonic anhydrase 30102
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60102
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
5'-AMP-activated protein kinase subunit gamma-10012
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Carbonic anhydrase 90102
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20012
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
5'-AMP-activated protein kinase subunit beta-10001
Beta-1 adrenergic receptor 0011
Beta-2 adrenergic receptor0202
Beta-1 adrenergic receptor0202
Beta-3 adrenergic receptor0202
Beta-1 adrenergic receptor0101
Bone morphogenetic protein receptor type-1B0011
Membrane-associated progesterone receptor component 10011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Dynamin-like 120 kDa protein, mitochondrial0011
Tyrosine-protein kinase JAK20011
Eukaryotic translation initiation factor 5B0011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0011
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
DNA topoisomerase 2-alpha0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Proto-oncogene tyrosine-protein kinase Src0011
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Ephrin type-A receptor 10011
Multifunctional protein ADE20011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Cyclin-dependent kinase 20011
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Deoxycytidine kinase0011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10112
DNA topoisomerase 2-beta0011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Mitogen-activated protein kinase kinase kinase kinase 20011
Serine/threonine-protein kinase 40011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Cyclin-dependent kinase 100011
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
MAP kinase-activated protein kinase 30011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
ATP-dependent RNA helicase DDX10011
Mitogen-activated protein kinase kinase kinase kinase 10011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Dual specificity testis-specific protein kinase 20011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Delta0101
Cycloeucalenol cycloisomerase0101
Sterol-8,7-isomerase0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Plasma kallikrein0001
Adenosine receptor A10001
Carbonic anhydrase0001
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Tubulin--tyrosine ligase0101
Monocarboxylate transporter 100001
Taste receptor type 2 member 140001
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]