Conditions > Enterocolitis, Neutropenic
Page last updated: 2024-09-27

Enterocolitis, Neutropenic

A syndrome characterized by inflammation in the ILEUM, the CECUM, and the ASCENDING COLON. It is observed in cancer patients with CHEMOTHERAPY-induced NEUTROPENIA or in other immunocompromised individuals (IMMUNOCOMPROMISED HOST).

Synonyms(3)

Synonym
Neutropenic Enterocolitis
Enterocolitis, Neutropenic
Ileocecal Syndrome

Research Excerpts

Overview

ExcerptReference
"Neutropenic enterocolitis is a common gastrointestinal complication in children undergoing chemotherapy for a variety of malignancies."( Aggarwal, SK; Gupta, S; Kapoor, S; Prakash, A; Ravi, RN, 2012)
"Neutropenic enterocolitis is a severe and potentially fatal complication of docetaxel-based treatment, especially when combined with other antineoplastic treatments known to cause neutropenia."( Amiri Kordestani, L; Bersoff-Matcha, SJ; Christopher Jones, S; Fedenko, K; Nayernama, A; Prowell, T; Singh, P, 2020)

Treatment

ExcerptReference
"The authors report neutropenic enterocolitis in a child undergoing chemotherapy for acute lymphoblastic lymphoma which presented with ileus along with a mass like lesion in the rectum."( Aggarwal, SK; Gupta, S; Kapoor, S; Prakash, A; Ravi, RN, 2012)

Research

Studies (28)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's11 (39.29)18.1394
2010's13 (46.43)28.8240
2020's4 (14.29)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carmustine0low10
gentamicin0low10
metronidazole0low10
cytarabine0low30
methylprednisolone0low10
podophyllotoxin0low10
camptothecin0low10
etoposide0low10
ribavirin0low10
idarubicin0low10
irinotecan0low20
methotrexate0low10
carbapenems0low10
docetaxel anhydrous0low80
trimethoprim, sulfamethoxazole drug combination0low20
carboplatin0low20
mycophenolic acid0low10
melphalan0low10
propylthiouracil0low10
alvocidib0low10
staurosporine0low10
midostaurin0low10
piperidines0low10
minocycline0low10
tigecycline0low10
nedaplatin0low10
ganciclovir0low10
valganciclovir0low10
aprepitant0low10

Protein Targets (986)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Protein (glycogen Phosphorylase)0101
Leukotriene C4 synthase0022
Glycogen synthase kinase-3 beta 0101
[Tau protein] kinase 0101
Bone morphogenetic protein receptor type-1B0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0022
Serine/threonine-protein kinase PLK40022
Serine/threonine-protein kinase 250022
ATP-dependent RNA helicase DDX3X0022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0022
Pyridoxal kinase0022
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase RIO30022
Dual specificity mitogen-activated protein kinase kinase 70022
Serine/threonine-protein kinase Chk10033
Inhibitor of nuclear factor kappa-B kinase subunit beta0022
Peripheral plasma membrane protein CASK0022
Aurora kinase A0123
Cyclin-G-associated kinase0022
Serine/threonine-protein kinase DCLK10022
Inhibitor of nuclear factor kappa-B kinase subunit alpha0022
Muscle, skeletal receptor tyrosine-protein kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Mitogen-activated protein kinase 130022
3-phosphoinositide-dependent protein kinase 10022
Mitogen-activated protein kinase kinase kinase 130022
Death-associated protein kinase 30022
Mitogen-activated protein kinase kinase kinase 70022
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10011
NUAK family SNF1-like kinase 10022
Dynamin-like 120 kDa protein, mitochondrial0022
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0022
Cyclin-T10202
UDP-glucuronosyltransferase 1A90002
Tyrosine-protein kinase JAK20022
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0022
Cyclin-K0101
Serine/threonine-protein kinase PAK 30022
Cyclin-dependent kinase-like 50022
Serine/threonine-protein kinase 17B0022
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30123
Cyclin-dependent kinase 140022
G2/mitotic-specific cyclin-B20102
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Serine/threonine-protein kinase OSR10022
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40022
Serine/threonine-protein kinase Chk20022
G1/S-specific cyclin-E20101
Glycogen phosphorylase, muscle form0101
Tyrosine-protein kinase ABL10235
Epidermal growth factor receptor0224
RAF proto-oncogene serine/threonine-protein kinase0022
Vitamin K-dependent protein C0101
Receptor tyrosine-protein kinase erbB-20224
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20022
Protein kinase C gamma type0101
ADP/ATP translocase 20022
Protein kinase C alpha type0101
Protein kinase C beta type0123
Insulin receptor0022
Tyrosine-protein kinase Lck0123
Tyrosine-protein kinase Fyn0123
Cyclin-dependent kinase 10225
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Macrophage colony-stimulating factor 1 receptor0123
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0022
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0022
Tyrosine-protein kinase HCK0022
Proto-oncogene tyrosine-protein kinase ROS0022
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Platelet-derived growth factor receptor beta0022
Tyrosine-protein kinase Fgr0022
Wee1-like protein kinase 20022
Uncharacterized serine/threonine-protein kinase SBK30022
Serine/threonine-protein kinase A-Raf0022
Mast/stem cell growth factor receptor Kit0123
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0123
Serine/threonine-protein kinase pim-10022
Fibroblast growth factor receptor 10123
DNA topoisomerase 2-alpha02311
Myosin light chain kinase, smooth muscle0022
Cyclin-dependent kinase 40225
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20213
Proto-oncogene tyrosine-protein kinase Src0224
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Insulin receptor-related protein0022
G2/mitotic-specific cyclin-B10102
Serine/threonine-protein kinase B-raf0022
G2/mitotic-specific cyclin-B0101
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Platelet-derived growth factor receptor alpha0022
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0123
cAMP-dependent protein kinase catalytic subunit alpha0123
Vascular endothelial growth factor receptor 1 0022
General transcription and DNA repair factor IIH helicase subunit XPD0022
Glycogen synthase kinase-3 beta0101
Interferon-induced, double-stranded RNA-activated protein kinase0022
Casein kinase II subunit alpha'0022
Cyclin-A20203
Ras-related protein Rab-6A0022
Serine/threonine-protein kinase MAK0022
Cyclin-dependent kinase 11B0022
Ephrin type-A receptor 10022
Fibroblast growth factor receptor 20022
Receptor tyrosine-protein kinase erbB-30022
Multifunctional protein ADE20022
Nucleoside diphosphate kinase B0011
Fibroblast growth factor receptor 40022
Dual specificity protein kinase CLK10101
Fibroblast growth factor receptor 30022
cAMP-dependent protein kinase catalytic subunit gamma0123
cAMP-dependent protein kinase catalytic subunit beta0123
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
G1/S-specific cyclin-D10102
Protein kinase C eta type0123
G1/S-specific cyclin-E10101
Cyclin-dependent kinase 20237
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Activin receptor type-2A0022
Mitogen-activated protein kinase 3 0123
MAP/microtubule affinity-regulating kinase 30022
Deoxycytidine kinase0023
Mitogen-activated protein kinase 10022
Ephrin type-A receptor 20022
Ephrin type-A receptor 30022
Ephrin type-A receptor 80022
Ephrin type-B receptor 20022
Leukocyte tyrosine kinase receptor0022
Non-receptor tyrosine-protein kinase TYK20022
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10022
G1/S-specific cyclin-D20102
G1/S-specific cyclin-D30102
Wee1-like protein kinase0022
Heme oxygenase 20022
Tyrosine-protein kinase receptor UFO0022
Mitogen-activated protein kinase 40022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-alpha serine/threonine-protein kinase0022
RAC-beta serine/threonine-protein kinase0022
G protein-coupled receptor kinase 40022
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Prostaglandin G/H synthase 20022
Myosin-100011
Tyrosine-protein kinase receptor Tie-10022
Vascular endothelial growth factor receptor 30022
Vascular endothelial growth factor receptor 20224
Dual specificity mitogen-activated protein kinase kinase 20022
Receptor-type tyrosine-protein kinase FLT30224
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
Serine/threonine-protein kinase receptor R30022
TGF-beta receptor type-20022
Electron transfer flavoprotein subunit beta0022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0123
Exosome RNA helicase MTR40022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0022
Serine/threonine-protein kinase mTOR0022
Megakaryocyte-associated tyrosine-protein kinase0022
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase TXK0022
Tyrosine-protein kinase ABL20022
Tyrosine-protein kinase FRK0022
Tyrosine-protein kinase ZAP-700123
Tyrosine-protein kinase SYK0022
26S proteasome regulatory subunit 6B0022
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 40022
Dual specificity mitogen-activated protein kinase kinase 30022
Casein kinase I isoform alpha0022
Casein kinase I isoform delta0022
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0022
MAP kinase-activated protein kinase 20022
Cyclin-dependent kinase 80022
Elongation factor Tu, mitochondrial0022
Choline-phosphate cytidylyltransferase A0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0123
Glycogen synthase kinase-3 beta0123
Cyclin-dependent kinase 70123
Cyclin-dependent kinase 90224
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0022
Interleukin-1 receptor-associated kinase 10022
Ribosomal protein S6 kinase alpha-30022
Cytoplasmic tyrosine-protein kinase BMX0022
cAMP-dependent protein kinase catalytic subunit PRKX0022
Cyclin-H0101
CDK-activating kinase assembly factor MAT10101
Serine/threonine-protein kinase Nek20022
Serine/threonine-protein kinase Nek30022
Serine/threonine-protein kinase Nek40022
Tyrosine-protein kinase JAK30022
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10022
Death-associated protein kinase 10022
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 120022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10022
5'-AMP-activated protein kinase catalytic subunit alpha-20022
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40022
Ephrin type-B receptor 10022
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Hormonally up-regulated neu tumor-associated kinase0022
Serine/threonine-protein kinase SIK10022
Receptor-interacting serine/threonine-protein kinase 40022
Ras-related protein Rab-100022
Cell division control protein 2 homolog0022
Actin-related protein 30022
Actin-related protein 20022
Calcium-dependent protein kinase 10022
GTP-binding nuclear protein Ran0022
Protein kinase C gamma type0101
Tubulin alpha-1A chain0022
Casein kinase II subunit alpha0022
Protein kinase C beta type0101
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0022
SRSF protein kinase 20022
Casein kinase I isoform gamma-20022
Cyclin-A10203
Mitogen-activated protein kinase kinase kinase 90022
Serine/threonine-protein kinase PknB0022
Cyclin-dependent kinase 30022
Cyclin-dependent kinase-like 10022
Cyclin-dependent kinase 60123
Cyclin-dependent-like kinase 5 0123
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
Cyclin homolog0101
ATP-dependent 6-phosphofructokinase, platelet type0022
Protein kinase C epsilon type0123
Dual specificity mitogen-activated protein kinase kinase 10022
Angiopoietin-1 receptor0022
Mitogen-activated protein kinase kinase kinase 100022
DNA topoisomerase 2-beta01311
Protein kinase C theta type0123
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10022
Protein kinase C zeta type0112
Protein kinase C delta type0123
Tyrosine-protein kinase BTK0022
Tyrosine-protein kinase receptor TYRO30022
Cyclin-dependent kinase 180022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Tyrosine-protein kinase ITK/TSK0123
Myotonin-protein kinase0022
Mitogen-activated protein kinase kinase kinase kinase 20022
Mitogen-activated protein kinase kinase kinase 120022
Tyrosine-protein kinase Mer0123
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Serine/threonine-protein kinase PAK 10022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
cGMP-dependent protein kinase 20022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Serine/threonine-protein kinase PRP4 homolog0022
Serine/threonine-protein kinase ATR0011
Receptor-interacting serine/threonine-protein kinase 10022
Calcium/calmodulin-dependent protein kinase type II subunit beta0022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0033
Cyclin-dependent kinase 130022
Calcium/calmodulin-dependent protein kinase type 10022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Cyclin-dependent kinase 5 activator 10101
Cyclin-dependent kinase 100011
Serine/threonine-protein kinase D10123
Serine/threonine-protein kinase 380022
Receptor tyrosine-protein kinase erbB-40022
Ribosomal protein S6 kinase alpha-20022
Ephrin type-A receptor 70022
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10022
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0022
Mitogen-activated protein kinase 110022
Serine/threonine-protein kinase STK110022
Rhodopsin kinase GRK10022
NT-3 growth factor receptor0022
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140022
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
BDNF/NT-3 growth factors receptor0022
Mitogen-activated protein kinase 60022
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0022
Discoidin domain-containing receptor 20022
AP2-associated protein kinase 10123
Myosin light chain kinase 30022
La-related protein 70101
Serine/threonine-protein kinase SBK10022
Mitogen-activated protein kinase kinase kinase 190022
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase TNNI3K0022
Rab-like protein 30022
Leucine-rich repeat serine/threonine-protein kinase 20022
Serine/threonine-protein kinase MRCK alpha0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0101
Protein kinase C eta type0101
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase Nek50022
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30022
Dual serine/threonine and tyrosine protein kinase0022
Mitogen-activated protein kinase kinase kinase 150022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
Serine/threonine-protein kinase tousled-like 20022
Serine/threonine-protein kinase 32C0022
Serine/threonine-protein kinase pim-30022
ATP-dependent RNA helicase DDX420011
Serine/threonine-protein kinase VRK20022
Myosin light chain kinase family member 40022
Homeodomain-interacting protein kinase 10022
Calcium/calmodulin-dependent protein kinase type 1D0022
Mitogen-activated protein kinase kinase kinase kinase 30022
Cyclin-dependent kinase-like 30022
MAP kinase-activated protein kinase 50022
Serine/threonine-protein kinase BRSK20022
Serine/threonine-protein kinase NIM10022
Serine/threonine-protein kinase ULK20022
Misshapen-like kinase 10022
Serine/threonine-protein kinase DCLK20022
Calcium/calmodulin-dependent protein kinase kinase 10022
Casein kinase I isoform alpha-like0022
Homeodomain-interacting protein kinase 40022
Myosin-IIIa0022
Ankyrin repeat and protein kinase domain-containing protein 10022
Serine/threonine-protein kinase Nek110022
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase BRSK10022
Serine/threonine-protein kinase 350022
Serine/threonine-protein kinase Nek70022
Rhodopsin kinase GRK70022
Serine/threonine-protein kinase 32A0022
G2/mitotic-specific cyclin-B30102
Myosin-IIIb0022
ATP-dependent RNA helicase DDX10022
Dual specificity tyrosine-phosphorylation-regulated kinase 20022
Cyclin-dependent kinase-like 20022
Mitogen-activated protein kinase kinase kinase kinase 10022
Serine/threonine-protein kinase Sgk30022
Atypical kinase COQ8B, mitochondrial0022
Aurora kinase B0022
MAP/microtubule affinity-regulating kinase 40022
Calcium/calmodulin-dependent protein kinase type 1G0022
Serine/threonine-protein kinase Nek10022
Cyclin-dependent kinase 150022
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20011
SRSF protein kinase 10022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0022
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Serine/threonine-protein kinase RIO10022
MAP kinase-interacting serine/threonine-protein kinase 10022
Serine/threonine-protein kinase RIO20022
Cyclin-dependent kinase 190022
Transient receptor potential cation channel subfamily M member 60022
Testis-specific serine/threonine-protein kinase 10022
Serine/threonine-protein kinase 330022
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20022
Serine/threonine-protein kinase DCLK30022
Cyclin-dependent kinase 10101
NUAK family SNF1-like kinase 20022
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
Myosin light chain kinase 2, skeletal/cardiac muscle0022
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
Homeodomain-interacting protein kinase 20022
Tyrosine-protein kinase Srms0022
Homeodomain-interacting protein kinase 30022
Serine/threonine-protein kinase PLK30022
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
MAP kinase-interacting serine/threonine-protein kinase 20022
Serine/threonine-protein kinase Nek60022
Casein kinase I isoform gamma-10022
Serine/threonine-protein kinase PAK 60022
SNF-related serine/threonine-protein kinase0022
Serine/threonine-protein kinase LATS20022
Serine/threonine-protein kinase 360022
Phenylalanine--tRNA ligase beta subunit0022
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Serine/threonine-protein kinase 32B0022
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120123
Serine/threonine-protein kinase PLK20022
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130022
Serine/threonine-protein kinase MARK10022
Serine/threonine-protein kinase pim-20022
Serine/threonine-protein kinase PAK 50022
Serine/threonine-protein kinase 260022
eIF-2-alpha kinase GCN20022
Serine/threonine-protein kinase NLK0022
Phosphatidylinositol 4-kinase beta0022
Serine/threonine-protein kinase 17A0022
STE20/SPS1-related proline-alanine-rich protein kinase0022
Ephrin type-A receptor 60022
5'-AMP-activated protein kinase subunit gamma-20022
Serine/threonine-protein kinase TBK10022
Septin-90022
Death-associated protein kinase 20022
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase tousled-like 10022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
ALK tyrosine kinase receptor0022
SRSF protein kinase 30022
Serine/threonine-protein kinase ICK0022
Cyclin-dependent kinase 11A0022
Aurora kinase C0022
Calcium/calmodulin-dependent protein kinase type II subunit alpha0022
Protein kinase C theta type0101
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase 38-like0022
Microtubule-associated serine/threonine-protein kinase 10022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Serine/threonine-protein kinase 240022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
hypoxia-inducible factor 1 alpha subunit4004
RAR-related orphan receptor gamma9009
GALC protein1001
TDP1 protein190019
GLI family zinc finger 39009
AR protein130013
caspase 7, apoptosis-related cysteine protease5005
estrogen receptor 2 (ER beta)7007
nuclear receptor subfamily 1, group I, member 3110011
progesterone receptor9009
cytochrome P450 family 3 subfamily A polypeptide 49009
glucocorticoid receptor [Homo sapiens]100010
retinoic acid nuclear receptor alpha variant 19009
retinoid X nuclear receptor alpha100010
estrogen-related nuclear receptor alpha150015
farnesoid X nuclear receptor8008
pregnane X nuclear receptor120012
estrogen nuclear receptor alpha170017
G6006
cytochrome P450 2D65005
peroxisome proliferator-activated receptor delta9009
peroxisome proliferator activated receptor gamma110011
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
caspase-35005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
thyroid stimulating hormone receptor5005
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x100010
thyroid hormone receptor beta isoform 2120012
heat shock protein beta-12002
nuclear factor erythroid 2-related factor 2 isoform 1130013
ATP-binding cassette sub-family C member 3015015
Multidrug resistance-associated protein 4015016
Voltage-dependent calcium channel gamma-2 subunit9009
Bile salt export pump015015
Interferon beta120012
HLA class I histocompatibility antigen, B alpha chain 6006
Cellular tumor antigen p53140014
Cytochrome P450 3A40505
Glutamate receptor 2101011
Substance-P receptor0213
Neuromedin-K receptor0101
Spike glycoprotein6017
Substance-P receptor0101
Inositol hexakisphosphate kinase 16006
Canalicular multispecific organic anion transporter 1017018
cytochrome P450 2C9, partial6006
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, Ferritin light chain4004
Chain A, Cruzipain1001
DNA topoisomerase 0101
thioredoxin reductase7007
15-lipoxygenase, partial3003
ATAD5 protein, partial5005
Fumarate hydratase5005
NFKB1 protein, partial2002
PPM1D protein8008
Thrombopoietin2002
aldehyde dehydrogenase 1 family, member A1120012
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)6006
thyroid stimulating hormone receptor5005
regulator of G-protein signaling 42002
EWS/FLI fusion protein120012
polyprotein5005
67.9K protein9009
glucocerebrosidase2002
putative alpha-glucosidase1001
alpha-galactosidase4004
euchromatic histone-lysine N-methyltransferase 2120012
Bloom syndrome protein isoform 16006
lysosomal alpha-glucosidase preproprotein1001
peripheral myelin protein 22 isoform 14004
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a3003
cytochrome P450 2C19 precursor2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
chromobox protein homolog 18008
nuclear factor erythroid 2-related factor 2 isoform 29009
huntingtin isoform 24004
ras-related protein Rab-9A3003
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
serine/threonine-protein kinase mTOR isoform 13003
DNA polymerase iota isoform a (long)7007
nuclear receptor ROR-gamma isoform 15005
geminin150015
survival motor neuron protein isoform d8008
cytochrome P450 3A4 isoform 17007
M-phase phosphoprotein 83003
muscleblind-like protein 1 isoform 15005
histone acetyltransferase KAT2A isoform 15005
relaxin receptor 1 isoform 11001
lethal factor (plasmid)4004
lamin isoform A-delta10110011
Gamma-aminobutyric acid receptor subunit pi7007
Telomerase reverse transcriptase0101
Histone deacetylase 30101
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0002
DNA ligase0101
Integrin beta-33104
Integrin alpha-IIb3003
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 10219
Gamma-aminobutyric acid receptor subunit beta-17007
Gamma-aminobutyric acid receptor subunit delta7007
Gamma-aminobutyric acid receptor subunit gamma-27007
Gamma-aminobutyric acid receptor subunit alpha-57007
Gamma-aminobutyric acid receptor subunit alpha-37007
Gamma-aminobutyric acid receptor subunit gamma-17007
Gamma-aminobutyric acid receptor subunit alpha-27007
Type-2 restriction enzyme BamHI0101
Gamma-aminobutyric acid receptor subunit alpha-47007
Gamma-aminobutyric acid receptor subunit gamma-37007
Gamma-aminobutyric acid receptor subunit alpha-67007
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
5-hydroxytryptamine receptor 2B0202
Type-2 restriction enzyme HindIII0101
D(1A) dopamine receptor3003
Histone deacetylase 40101
Ribonuclease pancreatic0101
Gamma-aminobutyric acid receptor subunit alpha-17007
Gamma-aminobutyric acid receptor subunit beta-37007
Gamma-aminobutyric acid receptor subunit beta-27007
Inositol monophosphatase 13003
DNA topoisomerase 10102
Histone deacetylase 10202
DNA topoisomerase 10101
Integrase 0202
Histone deacetylase 70101
GABA theta subunit7007
Histone deacetylase 20101
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80202
Gamma-aminobutyric acid receptor subunit epsilon7007
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 60202
Histone deacetylase 90101
Histone deacetylase 50101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
acetylcholinesterase4004
phosphopantetheinyl transferase7007
vitamin D3 receptor isoform VDRA6006
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase kappa isoform 14004
ATP-dependent phosphofructokinase7007
endonuclease IV4004
arylsulfatase A4004
thyroid hormone receptor beta isoform a5005
muscarinic acetylcholine receptor M12002
Bile salt export pump0202
Glutathione reductase, mitochondrial0101
Alpha-synuclein2002
Glutathione reductase0101
glp-1 receptor, partial4004
USP1 protein, partial6006
LMP1 [Human herpesvirus 4]0003
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0303
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
transactivating tegument protein VP16 [Human herpesvirus 1]0303
peripheral myelin protein 228008
nuclear receptor coactivator 3 isoform a0303
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0101
Thymidine kinase0101
Thymidylate synthase0203
Thymidine kinase0101
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Ataxin-2110011
Thymidine kinase0101
Deoxynucleoside kinase0101
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Luciferase2002
Microtubule-associated protein tau3003
aryl hydrocarbon receptor4004
activating transcription factor 64004
Caspase-72002
runt-related transcription factor 1 isoform AML1b1001
caspase-32002
core-binding factor subunit beta isoform 21001
mitogen-activated protein kinase 13003
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Transthyretin0101
NADH-ubiquinone oxidoreductase chain 40001
ATP-dependent translocase ABCB10408
72 kDa type IV collagenase0101
Carbonyl reductase [NADPH] 10001
Glutamate receptor 12103
Glutamate receptor 32103
Glutamate receptor 42103
Platelet-activating factor receptor1001
Multidrug resistance-associated protein 1 0204
Histamine H2 receptor1001
Reverse transcriptase/RNaseH 0101
ATPase family AAA domain-containing protein 58008
Broad substrate specificity ATP-binding cassette transporter ABCG20002
nuclear receptor subfamily 1, group I, member 24004
Serum paraoxonase/arylesterase 10303
Kinesin-like protein KIF110101
Nucleotide-binding oligomerization domain-containing protein 20202
SMAD family member 23003
SMAD family member 33003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
Regulatory protein E20022
ATP-dependent translocase ABCB10101
Cytochrome P450 2C9 0303
Polyunsaturated fatty acid lipoxygenase ALOX150101
DNA topoisomerase 20001
ATP-dependent translocase ABCB10202
UDP-glucuronosyltransferase 1A1 0103
Glutamate receptor ionotropic, NMDA 1 0001
Caspase-30101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
DNA topoisomerase 2-alpha 0001
Glutamate receptor ionotropic, NMDA 2D0001
Tubulin beta-2B chain0215
Similar to alpha-tubulin isoform 1 0215
Similar to alpha-tubulin isoform 1 0204
Glutamate receptor ionotropic, NMDA 3B0001
Solute carrier organic anion transporter family member 1B30405
Glutamate receptor ionotropic, NMDA 3A0001
Thymidine kinase 0101
ClpP2002
GLS protein3003
Solute carrier family 22 member 1 0102
POU domain, class 2, transcription factor 20001
Transitional endoplasmic reticulum ATPase0101
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60002
DNA polymerase III, partial1001
nonstructural protein 12002
NPYLR7B0011
Parkin1001
hexokinase-4 isoform 11001
NPC intracellular cholesterol transporter 1 precursor3003
D(1A) dopamine receptor1001
potassium voltage-gated channel subfamily H member 2 isoform d3003
glucokinase regulatory protein1001
DNA polymerase beta2002
flap endonuclease 12002
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
eyes absent homolog 2 isoform a1001
tumor susceptibility gene 101 protein1001
DNA polymerase eta isoform 12002
Amyloid-beta precursor protein1001
Single-stranded DNA cytosine deaminase1001
Chain A, Acetylcholinesterase0101
interferon gamma precursor0001
Solute carrier family 22 member 20101
Solute carrier family 22 member 30101
Interstitial collagenase0101
Acetylcholinesterase0101
Muscarinic acetylcholine receptor M40202
Alpha-2C adrenergic receptor0202
Acetylcholinesterase0202
Liver carboxylesterase 10001
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10101
thioredoxin glutathione reductase2002
Smad31001
importin subunit beta-1 isoform 12002
snurportin-12002
Nuclear receptor ROR-gamma3003
TAR DNA-binding protein 434004
Large neutral amino acids transporter small subunit 1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
dopamine D1 receptor1001
Thymidylate synthase 0101
IDH14004
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 31001
caspase-1 isoform alpha precursor1001
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Carbonic anhydrase 20011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40303
bromodomain adjacent to zinc finger domain 2B1001
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor0516
Glycine receptor subunit alpha-10404
Androgen receptor0202
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Lanosterol 14-alpha demethylase0101
tyrosine-protein kinase Yes1001
Protein delta homolog 10011
Aspartyl/asparaginyl beta-hydroxylase0101
Poly [ADP-ribose] polymerase tankyrase-20011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Albumin0011
Stromelysin-10101
Matrilysin0101
Multidrug transporter MdfA0101
Matrix metalloproteinase-90101
Cytochrome P450 2J20101
Protein mono-ADP-ribosyltransferase PARP150101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
Inosine-5'-monophosphate dehydrogenase 1 0202
Sodium-dependent serotonin transporter0101
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Chain A, Beta-lactamase2002
Genome polyprotein 0101
pregnane X receptor2002
Tubulin alpha-1A chain0225
Tubulin beta chain0224
Tubulin beta-4A chain0226
Integrin alpha-V 0101
Tubulin beta chain0226
60 kDa chaperonin0101
Tubulin alpha-3C chain0226
Botulinum neurotoxin type A 0101
Apoptosis regulator Bcl-20101
60 kDa heat shock protein, mitochondrial0101
UDP-glucuronosyltransferase 2B70101
UDP-glucuronosyltransferase 1-60101
Substance-K receptor0202
UDP-glucuronosyltransferase 1A40101
Cholecystokinin receptor type A0202
Melanocortin receptor 50202
UDP-glucuronosyltransferase 2B10 0101
Delta-type opioid receptor0202
10 kDa heat shock protein, mitochondrial0101
Tubulin alpha-1B chain0226
Tubulin alpha-4A chain0226
Tubulin beta-4B chain0226
Bcl-2-like protein 10101
Tubulin beta-3 chain0327
Tubulin beta-2A chain0226
Thiosulfate sulfurtransferase0101
Beta-tubulin 0101
Tubulin beta-8 chain0226
60 kDa chaperonin 0101
Tubulin alpha-3E chain0226
Tubulin alpha-1A chain0226
10 kDa chaperonin 0101
Tubulin alpha-1C chain0226
Tubulin beta-6 chain0226
Tubulin beta-2B chain0226
Tubulin beta-1 chain0226
Solute carrier organic anion transporter family member 1B10202
PAX80001
nuclear receptor subfamily 0 group B member 10101
steroidogenic factor 10101
Regulatory protein E20011
Regulatory protein E20011
Prostaglandin G/H synthase 10101
Cytochrome P450 2C190101
Prostaglandin G/H synthase 20101
Calcium-activated potassium channel subunit alpha-10101
interleukin 82002
NADH-cytochrome b5 reductase 3 0101
Myeloperoxidase0101
Thyroid peroxidase0101
Taste receptor type 2 member 380012
NS5 0011
Spike glycoprotein0011
Replicase polyprotein 1ab0011
glycogen synthase kinase-3 beta isoform 10011
Transmembrane protease serine 20011
Rap guanine nucleotide exchange factor 31001
Polymerase basic protein 20011
RNA-directed RNA polymerase catalytic subunit0011
Polymerase acidic protein0011
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Adenosine receptor A30101
Replicase polyprotein 1ab0011
Adenosylhomocysteinase0002
Adenosine receptor A2a0101
Adenosine receptor A10101
Adenosine receptor A10101
Genome polyprotein0011
Angiotensin-converting enzyme 2 0011
Chain A, Ribosomal protein S6 kinase alpha-10101
Chain X, Tyrosine-protein kinase Lyn0101
Chain A, Dual specificity protein kinase TTK0011
Chain A, Dual specificity protein kinase TTK0011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]