Page last updated: 2024-09-27

Endolymphatic Stromal Myosis

Neoplasms of the endometrial stroma that sometimes involve the MYOMETRIUM. These tumors contain cells that may closely or remotely resemble the normal stromal cells. Endometrial stromal neoplasms are divided into three categories: (1) benign stromal nodules; (2) low-grade stromal sarcoma, or endolymphatic stromal myosis; and (3) malignant endometrial stromal sarcoma (SARCOMA, ENDOMETRIAL STROMAL).

Synonyms(3)

Synonym
Sarcoma, Endometrial Stromal, Low-Grade
Endometrial Stromal Tumors
Endolymphatic Stromal Myosis

Research Excerpts

Research

Studies (18)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's6 (33.33)18.1394
2010's9 (50.00)28.8240
2020's3 (16.67)9.53
DrugIndicatedRelationship StrengthStudiesTrials
anastrozole0medium21
fluorouracil0low10
letrozole0low20
medroxyprogesterone acetate0low20
phenformin0low10
nitrilotriacetic acid0low10
megestrol acetate0low10
deoxycytidine0low10
stearoyl-2-lactylic acid0low10
technetium0medium11
gemcitabine0low10
triazoles0low30
bis-neodecanoato-1,2-diaminocyclohexaneplatinum(ii)0medium11
methotrexate0low10
docetaxel anhydrous0low10
tretinoin0low10
bromochloroacetic acid0low10
tamoxifen0low10
er-0865260low10
stearates0low10
interleukin-80low10
transforming growth factor beta0low10
cyclin d10low30

Protein Targets (426)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
AR protein100010
cytochrome P450 family 3 subfamily A polypeptide 46006
glucocorticoid receptor [Homo sapiens]8008
estrogen nuclear receptor alpha9009
G5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
thyroid hormone receptor beta isoform 28008
ATP-binding cassette sub-family C member 30909
Multidrug resistance-associated protein 409010
Bile salt export pump010010
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 5005
Aromatase0505
Cytochrome P450 2C9 0213
Amine oxidase [flavin-containing] A 0202
UDP-glucuronosyltransferase 1A40102
Spike glycoprotein4026
Inositol hexakisphosphate kinase 15005
Canalicular multispecific organic anion transporter 10909
cytochrome P450 2C9, partial5005
RAR-related orphan receptor gamma6006
aldehyde dehydrogenase 1 family, member A15005
nuclear receptor subfamily 1, group I, member 38008
retinoic acid nuclear receptor alpha variant 18008
thyroid stimulating hormone receptor5005
nuclear factor erythroid 2-related factor 2 isoform 19009
Cellular tumor antigen p538008
Nuclear receptor ROR-gamma2114
Thymidine kinase 2 0101
Deoxycytidine kinase0002
Probable deoxycytidylate deaminase0001
Cytidine deaminase0002
AAA family ATPase 0002
Reverse transcriptase/RNaseH 0011
PPM1D protein2002
TDP1 protein7007
GLI family zinc finger 36006
caspase 7, apoptosis-related cysteine protease2002
estrogen-related nuclear receptor alpha7007
farnesoid X nuclear receptor7007
pregnane X nuclear receptor6006
67.9K protein4004
peroxisome proliferator activated receptor gamma8008
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
caspase-32002
nuclear receptor subfamily 1, group I, member 23003
Serum paraoxonase/arylesterase 10101
Kinesin-like protein KIF110101
ATPase family AAA domain-containing protein 56006
Ataxin-26006
Nucleotide-binding oligomerization domain-containing protein 20101
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase2002
interleukin 82002
endonuclease IV1001
acetylcholinesterase2002
glp-1 receptor, partial1001
Skn7p0001
thioredoxin reductase3003
pregnane X receptor4004
hypoxia-inducible factor 1 alpha subunit3003
ATAD5 protein, partial3003
Microtubule-associated protein tau4004
Thrombopoietin1001
thyroid stimulating hormone receptor4004
estrogen receptor 2 (ER beta)4004
progesterone receptor5005
EWS/FLI fusion protein4004
nonstructural protein 13003
retinoid X nuclear receptor alpha6006
peroxisome proliferator-activated receptor delta6006
arylsulfatase A2002
IDH14004
euchromatic histone-lysine N-methyltransferase 26006
v-jun sarcoma virus 17 oncogene homolog (avian)3003
Histone H2A.x3003
peripheral myelin protein 22 isoform 11001
hemoglobin subunit beta1001
chromobox protein homolog 15005
nuclear factor erythroid 2-related factor 2 isoform 25005
huntingtin isoform 21001
flap endonuclease 12002
serine/threonine-protein kinase mTOR isoform 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
geminin7007
Vpr1001
peripheral myelin protein 224004
survival motor neuron protein isoform d4004
muscleblind-like protein 1 isoform 13003
lamin isoform A-delta105005
Voltage-dependent calcium channel gamma-2 subunit5005
Solute carrier family 22 member 80001
Epidermal growth factor receptor0202
Amyloid-beta precursor protein1102
Thymidylate synthase0303
Glutamate receptor 25005
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
ATP-dependent phosphofructokinase3003
Chain A, DEOXYNUCLEOSIDE KINASE0101
Spike glycoprotein0022
Replicase polyprotein 1ab0022
Transmembrane protease serine 20022
Procathepsin L0022
Replicase polyprotein 1a0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0022
Replicase polyprotein 1ab0022
Equilibrative nucleoside transporter 10101
Angiotensin-converting enzyme 2 0022
USP1 protein, partial5005
cytochrome P450 2C19 precursor1001
runt-related transcription factor 1 isoform AML1b1001
vitamin D3 receptor isoform VDRA4004
core-binding factor subunit beta isoform 21001
cytochrome P450 3A4 isoform 14004
Gamma-aminobutyric acid receptor subunit pi4004
Carbonic anhydrase 20213
Estrogen receptor0427
Steryl-sulfatase0101
Gamma-aminobutyric acid receptor subunit beta-14004
Cytochrome P450 11B1, mitochondrial0101
Gamma-aminobutyric acid receptor subunit delta4004
Gamma-aminobutyric acid receptor subunit gamma-24004
Cytochrome P450 11B2, mitochondrial0101
Gamma-aminobutyric acid receptor subunit alpha-54004
Gamma-aminobutyric acid receptor subunit alpha-34004
Gamma-aminobutyric acid receptor subunit gamma-14004
Gamma-aminobutyric acid receptor subunit alpha-24004
Gamma-aminobutyric acid receptor subunit alpha-44004
Gamma-aminobutyric acid receptor subunit gamma-34004
Gamma-aminobutyric acid receptor subunit alpha-64004
Gamma-aminobutyric acid receptor subunit alpha-14004
Gamma-aminobutyric acid receptor subunit beta-34004
Gamma-aminobutyric acid receptor subunit beta-24004
GABA theta subunit4004
Gamma-aminobutyric acid receptor subunit epsilon4004
Chain A, Beta-lactamase4004
Chain A, Cruzipain3003
SMAD family member 23003
SMAD family member 33003
PINK11001
Parkin2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
transcriptional regulator ERG isoform 33003
DNA polymerase iota isoform a (long)3003
neuropeptide S receptor isoform A2002
Glucocorticoid receptor0415
Sex hormone-binding globulin0011
Progesterone receptor0314
Glycine receptor subunit alpha-10404
Mineralocorticoid receptor 0101
Androgen receptor0224
Androgen receptor0606
Androgen receptor0011
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Histamine H2 receptor0404
5-hydroxytryptamine receptor 1B0303
Alpha-synuclein2103
Aldo-keto reductase family 1 member C30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G1001
Aldo-keto reductase family 1 member C10101
Estrogen receptor beta0325
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
bioA0001
DNA polymerase beta2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase2002
Chain A, Ferritin light chain3003
acid sphingomyelinase1001
dopamine D1 receptor1001
ClpP1001
15-lipoxygenase, partial1001
phosphopantetheinyl transferase3003
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
Bloom syndrome protein isoform 12002
cellular tumor antigen p53 isoform a2002
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
importin subunit beta-1 isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
DNA polymerase kappa isoform 12002
M-phase phosphoprotein 83003
histone acetyltransferase KAT2A isoform 12002
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0304
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Integrin beta-32002
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Integrin alpha-IIb2002
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 431001
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
Chain A, JmjC domain-containing histone demethylation protein 3A2002
apical membrane antigen 1, AMA12002
nonstructural protein 10101
thyroid hormone receptor beta isoform a2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
serine/threonine-protein kinase PLK11001
cytochrome P450 2D6 isoform 12002
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
Carbonic anhydrase 120101
Carbonic anhydrase 10101
Cytochrome P450 2D260101
Cytochrome P450 2D60112
Cytochrome P450 2D30101
Carbonic anhydrase 90101
Solute carrier family 22 member 10001
Cytochrome P450 2D40101
Chain A, CES1 protein0101
Fumarate hydratase1001
DNA polymerase III, partial1001
regulator of G-protein signaling 42002
polyprotein1001
glucocerebrosidase1001
bromodomain adjacent to zinc finger domain 2B2002
activating transcription factor 62002
thyrotropin-releasing hormone receptor2002
Caspase-72002
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
D(1A) dopamine receptor1001
caspase-32002
heat shock protein beta-12002
ubiquitin-conjugating enzyme E2 N0101
ras-related protein Rab-9A1001
nuclear receptor ROR-gamma isoform 12002
streptokinase A precursor0011
lethal factor (plasmid)1001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
5-hydroxytryptamine receptor 40202
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Receptor tyrosine-protein kinase erbB-20101
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
ATP-dependent translocase ABCB10213
Beta-1 adrenergic receptor0202
Cytochrome P450 3A40112
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Adenosine receptor A30404
Muscarinic acetylcholine receptor M10202
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Alpha-1B adrenergic receptor0404
Protein kinase C alpha type0101
Alpha-2B adrenergic receptor0202
5-hydroxytryptamine receptor 1A0303
Muscarinic acetylcholine receptor M30202
Cytochrome P450 2B60101
Substance-K receptor0202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
Prostaglandin G/H synthase 10101
Sodium-dependent noradrenaline transporter 0202
Thromboxane-A synthase 0101
Protein kinase C eta type0101
Alpha-1D adrenergic receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
Adenosine receptor A2a0202
B2 bradykinin receptor0202
Adenosine receptor A10202
Sodium-dependent serotonin transporter0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
5-hydroxytryptamine receptor 2B0404
Protein kinase C iota type0101
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0404
Histamine H2 receptor1001
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Sodium-dependent dopamine transporter 0202
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Potassium voltage-gated channel subfamily H member 20202
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Nuclear receptor subfamily 3 group C member 3 0202
Sigma non-opioid intracellular receptor 10202
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Chain A, Nuclear Receptor ROR-beta0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
GLS protein1001
thioredoxin glutathione reductase1001
aryl hydrocarbon receptor1001
Ornithine decarboxylase0001
Cytochrome P450 1A20011
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Alpha-1D adrenergic receptor0101
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2C190011
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]