| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| AR protein | 4 | 0 | 0 | 4 |
| aldehyde dehydrogenase 1 family, member A1 | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 2 | 0 | 0 | 2 |
| retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 4 | 0 | 0 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 6 | 0 | 0 | 6 |
| Voltage-dependent calcium channel gamma-2 subunit | 1 | 0 | 0 | 1 |
| Glutamate receptor 2 | 1 | 0 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 5 | 0 | 0 | 5 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN | 0 | 0 | 1 | 1 |
| thioredoxin reductase | 4 | 0 | 0 | 4 |
| phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
| NFKB1 protein, partial | 2 | 0 | 0 | 2 |
| GLS protein | 4 | 0 | 0 | 4 |
| thyroid stimulating hormone receptor | 4 | 0 | 0 | 4 |
| alpha-galactosidase | 2 | 0 | 0 | 2 |
| euchromatic histone-lysine N-methyltransferase 2 | 6 | 0 | 0 | 6 |
| cytochrome P450 2C19 precursor | 4 | 0 | 0 | 4 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| flap endonuclease 1 | 2 | 0 | 0 | 2 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| muscarinic acetylcholine receptor M1 | 5 | 0 | 0 | 5 |
| lethal factor (plasmid) | 3 | 0 | 0 | 3 |
| Cytochrome P450 3A4 | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, endothelial | 0 | 0 | 0 | 2 |
| Nitric oxide synthase, brain | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, brain | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, inducible | 0 | 0 | 0 | 1 |
| Nitric oxide synthase, inducible | 0 | 0 | 1 | 3 |
| Cationic amino acid transporter 3 | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 3 | 0 | 0 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 3 | 0 | 0 | 3 |
| Chain A, Ferritin light chain | 3 | 0 | 0 | 3 |
| arylsulfatase A | 4 | 0 | 0 | 4 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| Metabotropic glutamate receptor 6 | 0 | 0 | 1 | 1 |
| Excitatory amino acid transporter 4 | 0 | 1 | 0 | 1 |
| Glutamate transporter homolog | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 2 |
| N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 2 | 0 | 2 |
| Excitatory amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Excitatory amino acid transporter 2 | 0 | 1 | 0 | 1 |
| Excitatory amino acid transporter 3 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Metabotropic glutamate receptor 1 | 0 | 0 | 1 | 1 |
| Metabotropic glutamate receptor 2 | 0 | 0 | 1 | 1 |
| Carbonic anhydrase-like protein, putative | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 4 | 0 | 0 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 2 | 0 | 0 | 2 |
| cystic fibrosis transmembrane conductance regulator | 0 | 1 | 0 | 1 |
| DNA polymerase beta | 2 | 0 | 0 | 2 |
| short transient receptor potential channel 6 isoform 1 | 0 | 0 | 1 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 5 |
| 5-hydroxytryptamine receptor 4 | 0 | 4 | 0 | 4 |
| Bile salt export pump | 0 | 6 | 0 | 6 |
| Muscarinic acetylcholine receptor M2 | 0 | 3 | 2 | 8 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 1 | 5 |
| Muscarinic acetylcholine receptor M1 | 0 | 4 | 1 | 8 |
| Muscarinic acetylcholine receptor M3 | 0 | 4 | 1 | 8 |
| Muscarinic acetylcholine receptor M4 | 0 | 4 | 1 | 8 |
| Muscarinic acetylcholine receptor M5 | 0 | 4 | 1 | 8 |
| Muscarinic acetylcholine receptor M5 | 0 | 3 | 1 | 6 |
| Muscarinic acetylcholine receptor M2 | 0 | 4 | 1 | 9 |
| Muscarinic acetylcholine receptor M1 | 0 | 3 | 3 | 9 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 1 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 1 | 5 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 4 | 0 | 4 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor | 0 | 1 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
| IDH1 | 1 | 0 | 0 | 1 |
| geminin | 2 | 0 | 0 | 2 |
| Deoxycytidine kinase | 0 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| TDP1 protein | 2 | 0 | 0 | 2 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 isoform 1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit delta | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 2 | 0 | 2 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 2 | 0 | 3 |
| Neuronal acetylcholine receptor subunit alpha-4 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 2 | 0 | 3 |
| Neuronal acetylcholine receptor subunit beta-2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 0 | 2 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 2 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 3 | 3 | 2 | 8 |
| 5-hydroxytryptamine receptor 1A | 0 | 3 | 1 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 0 | 2 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 0 | 2 | 2 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 0 | 1 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 0 | 1 | 2 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit epsilon | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-7 | 0 | 1 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 3 | 3 | 2 | 8 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 3 | 3 | 2 | 8 |
| Gamma-aminobutyric acid receptor subunit theta | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Chain A, Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
| Chain A, HADH2 protein | 2 | 0 | 0 | 2 |
| Chain B, HADH2 protein | 2 | 0 | 0 | 2 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| estrogen-related nuclear receptor alpha | 3 | 0 | 0 | 3 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 3 | 0 | 0 | 3 |
| Cellular tumor antigen p53 | 2 | 0 | 0 | 2 |
| Thymidylate synthase | 0 | 2 | 0 | 2 |
| Thymidylate synthase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A3 | 0 | 1 | 0 | 1 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Multidrug resistance associated protein | 0 | 0 | 0 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| beta-2 adrenergic receptor | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 2A1 | 0 | 1 | 0 | 1 |
| Chain A, Methionyl-tRNA synthetase | 0 | 0 | 1 | 1 |
| Chain A, Methionyl-tRNA synthetase | 0 | 0 | 1 | 1 |
| Chain A, Aminopeptidase | 0 | 1 | 0 | 1 |
| Chain A, Methionine aminopeptidase | 0 | 1 | 0 | 1 |
| S-ribosylhomocysteine lyase | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 5 | 0 | 0 | 0 | 1 |
| S-adenosylmethionine synthase isoform type-1 | 0 | 0 | 0 | 1 |
| S-adenosylmethionine synthase isoform type-2 | 0 | 0 | 0 | 1 |
| Fatty acid synthase | 0 | 1 | 0 | 1 |
| Large neutral amino acids transporter small subunit 1 | 0 | 1 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 2 | 0 | 0 | 2 |
| pyruvate kinase PKM isoform b | 1 | 0 | 0 | 1 |
| Ornithine decarboxylase | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 3 | 0 | 0 | 3 |
| Cytochrome P450 2A6 | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor DM1 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 1 | 0 | 0 | 1 |
| Cytochrome P450 2A13 | 0 | 1 | 1 | 2 |
| Glutamate 5-kinase | 0 | 0 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter A | 0 | 1 | 0 | 1 |
| Neutral amino acid transporter B(0) | 0 | 1 | 0 | 1 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Amino acid transporter | 0 | 1 | 0 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| Chain A, Ferritin light chain | 0 | 0 | 1 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A9 | 0 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent GABA transporter 1 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | 0 | 1 | 0 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Sodium- and chloride-dependent betaine transporter | 0 | 1 | 0 | 1 |
| Fatty-acid amide hydrolase 1 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A8 | 0 | 0 | 0 | 1 |
| Pyridoxal kinase | 0 | 0 | 0 | 1 |
| Thymidine phosphorylase | 0 | 1 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 0 | 1 | 1 |
| Beta-2 adrenergic receptor | 0 | 2 | 0 | 2 |
| Beta-1 adrenergic receptor | 0 | 2 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| Beta-3 adrenergic receptor | 0 | 2 | 0 | 2 |
| Beta-1 adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| Beta-2 adrenergic receptor | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |