Page last updated: 2024-09-27

Dysarthria, Pseudobulbar

A syndrome characterized by DYSARTHRIA, dysphagia, dysphonia, impairment of voluntary movements of tongue and facial muscles, and emotional lability. This condition is caused by diseases that affect the motor fibers that travel from the cerebral cortex to the lower BRAIN STEM (i.e., corticobulbar tracts); including MULTIPLE SCLEROSIS; MOTOR NEURON DISEASE; and CEREBROVASCULAR DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, p489)

Synonyms(8)

Synonym
Dysarthria, Pseudobulbar
Pseudobulbar Syndrome
Paralysis, Pseudobulbar
Pseudobulbar Paresis
Spastic Bulbar Palsy
Pseudobulbar Paralysis
Pseudobulbar Palsy
Pseudobulbar Mutism

Research

Studies (36)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's16 (44.44)18.1394
2010's19 (52.78)28.8240
2020's1 (2.78)9.53
DrugIndicatedRelationship StrengthStudiesTrials
salicylic acid0medium11
phenytoin0low10
bisoprolol0low10
citalopram0low10
valproic acid0low10
riluzole0low20
serine0low10
levodopa0low10
threonine0low10
thiophenes0low10
diphenhydramine hydrochloride0low10
glutamic acid0medium11
fomesafen0low10
n 0437, (-)-isomer0low10
aripiprazole0low10
fluorodeoxyglucose f180low10
sertraline0low20
pramipexole0low10
methotrexate0low10
quinidine0medium204
D-fructopyranose0low10
pica0low10
topiramate0low10
deamino arginine vasopressin0low10
dextromethorphan0medium204
dextromethorphan - quinidine combination0medium113

Protein Targets (599)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, JmjC domain-containing histone demethylation protein 3A2002
5-hydroxytryptamine receptor 3E0101
acetylcholinesterase3003
hypoxia-inducible factor 1 alpha subunit3003
RAR-related orphan receptor gamma2002
SMAD family member 22002
Fumarate hydratase2002
USP1 protein, partial5005
PPM1D protein2002
SMAD family member 32002
TDP1 protein9009
GLI family zinc finger 35005
Microtubule-associated protein tau3003
AR protein100010
estrogen receptor 2 (ER beta)3003
nuclear receptor subfamily 1, group I, member 38008
progesterone receptor4004
EWS/FLI fusion protein5005
glucocorticoid receptor [Homo sapiens]7007
retinoic acid nuclear receptor alpha variant 16006
retinoid X nuclear receptor alpha5005
estrogen-related nuclear receptor alpha100010
farnesoid X nuclear receptor3003
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha140014
G4004
cytochrome P450 2D64004
polyprotein2002
67.9K protein3003
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
euchromatic histone-lysine N-methyltransferase 29009
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyroid stimulating hormone receptor3003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)4004
lysosomal alpha-glucosidase preproprotein2002
mu-type opioid receptor isoform MOR-10022
nuclear factor erythroid 2-related factor 2 isoform 22002
potassium voltage-gated channel subfamily H member 2 isoform d6006
transcriptional regulator ERG isoform 33003
thyroid hormone receptor beta isoform 26006
heat shock protein beta-11001
nuclear factor erythroid 2-related factor 2 isoform 16006
nuclear receptor ROR-gamma isoform 13003
geminin7007
peripheral myelin protein 227007
histone acetyltransferase KAT2A isoform 13003
5-hydroxytryptamine receptor 2A0022
neuropeptide S receptor isoform A1001
Solute carrier family 22 member 20101
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40809
5-hydroxytryptamine receptor 3A0101
Voltage-dependent calcium channel gamma-2 subunit4004
5-hydroxytryptamine receptor 3B0101
Bile salt export pump011011
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 4004
Cellular tumor antigen p536006
ATP-dependent translocase ABCB10405
Cytochrome P450 3A40505
5-hydroxytryptamine receptor 1A0213
5-hydroxytryptamine receptor 2C0203
Neuronal acetylcholine receptor subunit alpha-42002
Neuronal acetylcholine receptor subunit beta-22002
D(2) dopamine receptor0549
5-hydroxytryptamine receptor 2A0202
Alpha-1B adrenergic receptor0101
Alpha-2C adrenergic receptor0404
D0303
5-hydroxytryptamine receptor 1A0303
Glutamate receptor 24217
Muscarinic acetylcholine receptor M30202
D(1A) dopamine receptor0224
D(4) dopamine receptor0314
D(1B) dopamine receptor0202
Alpha-1D adrenergic receptor0101
Alpha-1D adrenergic receptor0303
5-hydroxytryptamine receptor 2A0415
5-hydroxytryptamine receptor 2C0606
D(4) dopamine receptor0202
Histamine H1 receptor0101
Sodium-dependent serotonin transporter0729
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 70202
Alpha-1A adrenergic receptor0303
Histamine H1 receptor0415
Alpha-1B adrenergic receptor0101
D(3) dopamine receptor0337
5-hydroxytryptamine receptor 2B0505
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 3A0202
5-hydroxytryptamine receptor 60202
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Spike glycoprotein5005
D(2) dopamine receptor0415
Inositol monophosphatase 13003
Potassium voltage-gated channel subfamily H member 20909
5-hydroxytryptamine receptor 3D0101
Multidrug and toxin extrusion protein 20101
5-hydroxytryptamine receptor 3C0101
Inositol hexakisphosphate kinase 14004
Canalicular multispecific organic anion transporter 10808
Multidrug and toxin extrusion protein 10202
Histamine H3 receptor0101
cytochrome P450 2C9, partial4004
ATAD5 protein, partial4004
arylsulfatase A4004
chromobox protein homolog 17007
DNA polymerase kappa isoform 14004
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0011
Beta-3 adrenergic receptor0112
Beta-1 adrenergic receptor0101
thioredoxin reductase8008
aldehyde dehydrogenase 1 family, member A15005
NPC intracellular cholesterol transporter 1 precursor3003
D(1A) dopamine receptor2002
survival motor neuron protein isoform d5005
Solute carrier family 22 member 1 0405
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 40404
Aldo-keto reductase family 1 member B10707
Tryptophan 5-hydroxylase 10101
Angiotensin-converting enzyme0404
Aldo-keto reductase family 1 member B10202
Acetylcholinesterase0202
Aromatase0101
Sodium-dependent noradrenaline transporter 0617
Sodium-dependent dopamine transporter0202
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 70202
Sodium-dependent dopamine transporter 0314
Sigma intracellular receptor 20202
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Nuclear receptor subfamily 3 group C member 3 0404
Ataxin-25005
Sigma non-opioid intracellular receptor 10606
Sigma non-opioid intracellular receptor 10303
Transporter0303
ATP-dependent phosphofructokinase3003
Vasopressin V2 receptor0112
Oxytocin receptor0011
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Translocator protein0101
Vasopressin V2 receptor 0112
thyroid stimulating hormone receptor2002
cytochrome P450 2D6 isoform 11001
muscarinic acetylcholine receptor M14004
Glutamate receptor ionotropic, NMDA 2D0202
Glutamate receptor ionotropic, NMDA 3B0202
Neuronal acetylcholine receptor subunit alpha-30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0404
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2D10202
Cytochrome P450 2D260202
Cytochrome P450 2D60506
Muscarinic acetylcholine receptor M20101
Cytochrome P450 2C9 0505
Neuronal acetylcholine receptor subunit beta-40101
Cytochrome P450 2D30202
Glutamate receptor ionotropic, NMDA 1 0315
Cytochrome P450 2J20202
Taste receptor type 2 member 460011
Glutamate receptor ionotropic, NMDA 2A 0315
Glutamate receptor ionotropic, NMDA 2B0416
Glutamate receptor ionotropic, NMDA 2C0315
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Sigma non-opioid intracellular receptor 10303
Glutamate receptor ionotropic, NMDA 2D0315
Cytochrome P450 2D40202
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0315
Glutamate receptor ionotropic, NMDA 3A0315
Chain A, 2-oxoglutarate Oxygenase5005
endonuclease IV2002
peripheral myelin protein 22 isoform 13003
thyroid hormone receptor beta isoform a3003
mitogen-activated protein kinase 11001
eyes absent homolog 2 isoform a1001
DNA polymerase iota isoform a (long)3003
lamin isoform A-delta104004
Alpha-synuclein2002
TAR DNA-binding protein 433003
Luciferase4004
Histone H2A.x3003
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
glp-1 receptor, partial3003
phosphopantetheinyl transferase5005
GLS protein3003
regulator of G-protein signaling 44004
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Excitatory amino acid transporter 40101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Carbonic anhydrase 10407
Carbonic anhydrase 20429
Integrin beta-32013
Integrin alpha-IIb2013
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE3003
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
dopamine D1 receptor2002
15-lipoxygenase, partial3003
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA11001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
pyruvate kinase2002
Bloom syndrome protein isoform 14004
hexokinase-4 isoform 11001
atrial natriuretic peptide receptor 1 precursor2002
glucokinase regulatory protein1001
importin subunit beta-1 isoform 12002
flap endonuclease 14004
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
snurportin-12002
DNA polymerase eta isoform 12002
M-phase phosphoprotein 82002
Polyphenol oxidase 20103
Carbonic anhydrase 120204
Epidermal growth factor receptor0101
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Carbonic anhydrase 30203
Polyunsaturated fatty acid lipoxygenase ALOX150101
Tyrosinase0101
Carbonic anhydrase 40204
Carbonic anhydrase 60204
Adenosine receptor A10001
Adenosine receptor A2a0001
Carbonic anhydrase 5A, mitochondrial0215
Carbonic anhydrase0102
Carbonic anhydrase 70204
Solute carrier family 15 member 10101
Carbonic anhydrase0102
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 90204
Carbonic anhydrase 0102
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0102
Monocarboxylate transporter 100001
Carbonic anhydrase 150203
Carbonic anhydrase 130204
Carbonic anhydrase 140204
Carbonic anhydrase 5B, mitochondrial0204
phosphoglycerate kinase1001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain A, Ferritin light chain1001
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
IDH13003
Thymidylate synthase 0101
cellular tumor antigen p53 isoform a2002
polyunsaturated fatty acid lipoxygenase ALOX121001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
vitamin D3 receptor isoform VDRA2002
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
muscleblind-like protein 1 isoform 11001
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0303
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0304
Dihydrofolate reductase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10303
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60102
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80102
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
ATPase family AAA domain-containing protein 53003
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
cytochrome P450 family 3 subfamily A polypeptide 41001
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
D(2) dopamine receptor0101
D0202
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Gamma-aminobutyric acid 0101
cytochrome P450 2C9 precursor2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit pi2103
Gamma-aminobutyric acid receptor subunit delta0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-12103
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit delta2103
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit gamma-22103
Gamma-aminobutyric acid receptor subunit alpha-52103
Gamma-aminobutyric acid receptor subunit alpha-32103
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit gamma-12103
Gamma-aminobutyric acid receptor subunit alpha-22103
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-42103
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit gamma-32103
Gamma-aminobutyric acid receptor subunit alpha-62103
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0102
Histamine H2 receptor2002
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit alpha-12103
Gamma-aminobutyric acid receptor subunit beta-32103
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit beta-22103
Gamma-aminobutyric acid receptor subunit epsilon0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0101
GABA theta subunit2103
Sodium channel protein type 2 subunit alpha0101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon2103
Gamma-aminobutyric acid receptor subunit theta0101
Sodium channel protein type 3 subunit alpha0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0101
Muscarinic acetylcholine receptor M20303
Alpha-2A adrenergic receptor0303
Muscarinic acetylcholine receptor M10303
Alpha-2B adrenergic receptor0303
D(3) dopamine receptor0213
Histamine H2 receptor0123
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1E0101
Delta-type opioid receptor0101
5-hydroxytryptamine receptor 5A0101
Solute carrier family 22 member 10204
Histamine H4 receptor0112
Solute carrier family 22 member 20203
Chain A, Beta-lactamase2002
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
cytochrome P450 3A4 isoform 12002
Solute carrier organic anion transporter family member 1A40101
Histidine-rich protein PFHRP-II0101
Cholinesterase0101
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 2B70203
UDP-glucuronosyltransferase 1-60102
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0202
UDP-glucuronosyltransferase 1A40101
Potassium voltage-gated channel subfamily A member 50101
UDP-glucuronosyltransferase 2B10 0101
Solute carrier organic anion transporter family member 1A10101
Cholinesterase0202
Potassium voltage-gated channel subfamily D member 20101
Multidrug resistance protein 1a0001
NFKB1 protein, partial1001
nonstructural protein 12002
Parkin1001
histone deacetylase 9 isoform 31001
ras-related protein Rab-9A2002
pyruvate kinase PKM isoform b1001
Potassium channel subfamily K member 20011
Cytochrome P450 1A20101
Ornithine decarboxylase1001
Cytochrome P450 2C190303
Disintegrin and metalloproteinase domain-containing protein 171001
chaperonin-containing TCP-1 beta subunit homolog1001
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
5'-AMP-activated protein kinase subunit beta-20001
Albumin0101
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
Prostaglandin G/H synthase 10101
Cystathionine gamma-lyase0101
Prostaglandin G/H synthase 20101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
lethal factor (plasmid)1001
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Smad31001
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 11001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Rap guanine nucleotide exchange factor 31001
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Transcriptional activator protein LuxR0101
D(1B) dopamine receptor0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Melanocortin receptor 50202
D(1A) dopamine receptor1001
Envelope glycoprotein0011
activating transcription factor 61001
Chain A, Carbonic anhydrase 10101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase0101
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110001
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80101
Arachidonate 5-lipoxygenase-activating protein0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 20101
Delta-type opioid receptor0101
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
Carbonic anhydrase 130101
Carbonic anhydrase 40202
pregnane X receptor1001
Cocaine esterase0101
Histone deacetylase 30202
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Nuclear receptor ROR-gamma1001
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]