Agyria-Pachygyria-Band Spectrum

Disorders comprising a spectrum of brain malformations representing the paradigm of a diffuse neuronal migration disorder. They result in cognitive impairment; SEIZURES; and HYPOTONIA or spasticity. Mutations of two genes, LIS1, the gene for the non-catalytic subunit of PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB; and DCX or XLIS, the gene for doublecortin, have been identified as the most common causes of disorders in this spectrum. Additional variants of classical (Type I) lissencephaly have been linked to RELN, the gene for reelin, and ARX, the gene for aristaless related homeobox protein. (From Leventer, R.J., et al, Mol Med Today. 2000 Jul;6(7):277-84 and Barkovich, A.J., et al, Neurology. 2005 Dec 27;65(12):1873-87.)

Synonym
Miller-Dieker Lissencephaly Syndrome
Lissencephaly 1
Heterotopia, Subcortical Band
Lissencephalies, Classical
Classic Lissencephaly
Double Cortex Syndrome
Lissencephaly, X-Linked, 1
Classical Lissencephalies and Subcortical Band Heterotopias
Classical Lissencephaly Syndrome
Subcortical Laminar Heterotopia
Lissencephaly, X-Linked
Lissencephaly, Type 1
Lissencephaly, Miller-Dieker
Isolated Lissencephaly Sequence
Subcortical Band Heterotopia
Lissencephaly-Subcortical Band Heterotopia
X-Linked Lissencephaly
Type 1 Lissencephaly
Lissencephaly Type 1
Lissencephaly, Classic
Lissencephaly Syndrome, Miller-Dieker
Miller-Dieker Syndrome
Chromosome 17p13.3 Deletion Syndrome
Agyria-Pachygyria-Band Spectrum
Lissencephaly Sequence, Isolated

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	5 (22.73)	18.1394
2010's	11 (50.00)	28.8240
2020's	6 (27.27)	9.53

Drug	Relationship Strength	Studies
gamma-aminobutyric acid	low	3
carmustine	low	1
valproic acid	low	2
lamotrigine	low	2
phenobarbital	low	1
vigabatrin	low	1
thyroxine	low	1
pentylenetetrazole	low	2
triiodothyronine	low	1
bromodeoxyuridine	low	2
bicuculline	low	1
fluorodeoxyglucose f18	low	3
trichostatin a	low	1
cocaine	low	1
propylthiouracil	low	1
freedom	low	1
levetiracetam	low	1
cysteine	low	1
cholecystokinin	low	2
neuropeptide y	low	1
oligonucleotides	low	1
technetium tc 99m bicisate	low	1
gq1b ganglioside	low	1

Protein Targets (366)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
thioredoxin reductase	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	11	0	0	11
chromobox protein homolog 1	6	0	0	6
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
geminin	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	0	4	0	4
Gamma-aminobutyric acid receptor subunit delta	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-3	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-5	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-3	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	4	1	5
Gamma-aminobutyric acid receptor subunit epsilon	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	0	4	1	5
Gamma-aminobutyric acid receptor subunit gamma-1	0	4	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	0	4	0	4
Gamma-aminobutyric acid receptor subunit theta	0	4	0	4
interleukin 8	2	0	0	2
pregnane X receptor	2	0	0	2
RAR-related orphan receptor gamma	2	0	0	2
ATAD5 protein, partial	5	0	0	5
TDP1 protein	5	0	0	5
Microtubule-associated protein tau	3	0	0	3
AR protein	3	0	0	3
aldehyde dehydrogenase 1 family, member A1	4	0	0	4
nuclear receptor subfamily 1, group I, member 3	3	0	0	3
progesterone receptor	2	0	0	2
glucocorticoid receptor [Homo sapiens]	3	0	0	3
retinoic acid nuclear receptor alpha variant 1	2	0	0	2
retinoid X nuclear receptor alpha	2	0	0	2
estrogen-related nuclear receptor alpha	5	0	0	5
pregnane X nuclear receptor	4	0	0	4
estrogen nuclear receptor alpha	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
arylsulfatase A	4	0	0	4
IDH1	1	0	0	1
nuclear receptor subfamily 1, group I, member 2	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
Nuclear hormone receptor family member daf-12	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	2	0	0	2
thyroid hormone receptor beta isoform 2	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
oxysterols receptor LXR-beta isoform 1	0	0	1	1
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
peripheral myelin protein 22	3	0	0	3
survival motor neuron protein isoform d	2	0	0	2
muscarinic acetylcholine receptor M1	3	0	0	3
Voltage-dependent calcium channel gamma-2 subunit	1	0	0	1
Thymidine kinase, cytosolic	0	1	0	1
Glutamate receptor 2	1	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Nuclear receptor ROR-gamma	2	0	0	2
Spike glycoprotein	1	0	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
endonuclease IV	2	0	0	2
GLI family zinc finger 3	1	0	0	1
thyroid stimulating hormone receptor	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	3	0	0	3
EWS/FLI fusion protein	5	0	0	5
cytochrome P450 2D6	2	0	0	2
peroxisome proliferator activated receptor gamma	5	0	0	5
Bloom syndrome protein isoform 1	5	0	0	5
peripheral myelin protein 22 isoform 1	2	0	0	2
thyroid hormone receptor beta isoform a	5	0	0	5
huntingtin isoform 2	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	5	0	0	5
nuclear receptor ROR-gamma isoform 1	1	0	0	1
ATP-binding cassette sub-family C member 3	0	4	0	4
Multidrug resistance-associated protein 4	0	4	0	4
Bile salt export pump	0	2	0	2
Bile salt export pump	0	9	0	9
Glutathione reductase, mitochondrial	0	1	0	1
Cellular tumor antigen p53	4	0	0	4
Alpha-synuclein	2	0	0	2
Glutathione reductase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	4	0	4
ATP-dependent phosphofructokinase	3	0	0	3
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	0	1	0	1
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Liver carboxylesterase 1	0	1	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	3
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
D(2) dopamine receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Transporter	0	2	0	2
Chain A, Ferritin light chain	2	0	0	2
Gamma-aminobutyric acid	0	0	1	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
regulator of G-protein signaling 4	3	0	0	3
D(1A) dopamine receptor	3	0	0	3
transcriptional regulator ERG isoform 3	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
histone acetyltransferase KAT2A isoform 1	2	0	0	2
lamin isoform A-delta10	4	0	0	4
neuropeptide S receptor isoform A	2	0	0	2
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Histone deacetylase 3	0	5	0	7
Gamma-aminobutyric acid type B receptor subunit 2	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit delta	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	0	1	1
Histone deacetylase 4	0	5	1	9
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	0	1	1
Gamma-aminobutyric acid receptor subunit beta-2	0	2	2	4
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
TAR DNA-binding protein 43	1	0	0	1
Histone deacetylase 1	0	5	2	9
Sterol O-acyltransferase 1	0	0	1	1
Proton-coupled amino acid transporter 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	0	1	1
Histone deacetylase 7	0	5	0	7
GABA theta subunit	0	2	1	3
Histone deacetylase 2	0	5	1	8
Polyamine deacetylase HDAC10	0	5	0	7
Histone deacetylase 11	0	5	0	7
Histone deacetylase 8	0	5	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	1	1
Gamma-aminobutyric acid receptor subunit epsilon	0	2	1	3
Platelet glycoprotein VI	0	0	1	1
Gamma-aminobutyric acid receptor subunit theta	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	0	1	1
Histone deacetylase 6	0	5	1	8
Gamma-aminobutyric acid type B receptor subunit 1	0	1	1	2
Histone deacetylase 9	0	5	0	7
Histone deacetylase 5	0	5	0	7
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	2	0	0	2
GALC protein	1	0	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
mitogen-activated protein kinase 1	1	0	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
flap endonuclease 1	1	0	0	1
Synaptic vesicle glycoprotein 2A	0	1	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
GLS protein	1	0	0	1
DNA polymerase kappa isoform 1	2	0	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	1	0	0	1
phosphopantetheinyl transferase	1	0	0	1
peroxisome proliferator-activated receptor delta	2	0	0	2
vitamin D (1,25- dihydroxyvitamin D3) receptor	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	2	0	0	2
NADH-cytochrome b5 reductase 3	0	1	0	1
Myeloperoxidase	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
USP1 protein, partial	3	0	0	3
apical membrane antigen 1, AMA1	2	0	0	2
G	1	0	0	1
aryl hydrocarbon receptor	2	0	0	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Interferon beta	2	0	0	2
HLA class I histocompatibility antigen, B alpha chain	1	0	0	1
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Inositol hexakisphosphate kinase 1	1	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
cytochrome P450 2C9, partial	1	0	0	1
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Histone deacetylase 8	0	1	0	1
PPM1D protein	1	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
glucocerebrosidase	2	0	0	2
unnamed protein product	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
vitamin D3 receptor isoform VDRA	1	0	0	1
Histone deacetylase 1	0	2	0	2
5-hydroxytryptamine receptor 3A	0	1	0	1
Histone deacetylase 3	0	1	0	1
Plasma kallikrein	0	1	0	1
Integrin beta-3	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Integrin alpha-IIb	0	1	0	1
Coagulation factor VII	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Cytochrome P450 2D6	0	1	0	1
Vitamin D3 receptor	0	1	0	1
Cytochrome P450 2C9	0	1	0	1
Tissue factor	0	2	0	2
Adenosine receptor A1	0	1	0	1
Cytochrome P450 2C19	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Histamine H2 receptor	0	1	0	1
Histone deacetylase 2	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Histone deacetylase 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Histone deacetylase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	0	2
Histone deacetylase 7	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	1	2
Histone deacetylase 8	0	1	0	1
Histone deacetylase 11	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 5	0	1	0	1
Histone deacetylase	0	1	0	1
glp-1 receptor, partial	1	0	0	1
farnesoid X nuclear receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Prothrombin	0	0	1	1
Androgen receptor	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	1	2
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Luciferase	1	0	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Agyria-Pachygyria-Band Spectrum

Synonyms(25)

Research Excerpts

Research

Studies (22)

Protein Targets (366)

Agyria-Pachygyria-Band Spectrum

Synonyms(25)

Research Excerpts

Research

Studies (22)

Drugs Studied (27)

Protein Targets (366)