Page last updated: 2024-09-27

Dihydropyrimidine Dehydrogenase Deficiency

An autosomal recessive disorder affecting DIHYDROPYRIMIDINE DEHYDROGENASE and causing familial pyrimidinemia. It is characterized by thymine-uraciluria in homozygous deficient patients. Even a partial deficiency in the enzyme leaves individuals at risk for developing severe 5-FLUOROURACIL-associated toxicity.

Synonyms(8)

Synonym
Dihydropyrimidine Dehydrogenase Deficiency
Familial Pyrimidemia
Familial Pyrimidinemia
Pyrimidinemia, Familial
Hereditary Thymine-Uraciluria
Thymine-Uraciluria, Hereditary
Dihydropyrimidinuria
DPD Deficiency

Research Excerpts

Overview

ExcerptReference
"DPD deficiency is a pharmacogenetic syndrome which is also present in the Indian population."( Carollo, T; Diasio, RB; Ezzeldin, H; Mattison, L; Saif, MW, 2006)
"DPD deficiency is a pharmacogenetics syndrome associated with severe/lethal toxicities upon 5-FU or capecitabine intake."( Bagarry-Liegey, D; Blesius, A; Brunet, C; Chefrour, M; Ciccolini, J; Dahan, L; Duffaud, F; Favre, R; Ferri-Dessens, RM; Frances, N; Giovanni, A; Lacarelle, B; Marouani, H; Mercier, C; Seitz, JF; Varoquaux, A; Yang, CG; Zanaret, M, 2011)
"While DPD deficiencyis veryrare, we need to consider that 5-FU causes severe adverse events in patients with DPD deficiency."( Arita, S; Koike, N; Oshima, Y; Takeuchi, T; Watanabe, H, 2018)
"Dihydropyrimidine dehydrogenase deficiency is a rare inherited disorder."( Burns, K; Findlay, M; Helsby, N; Porter, D; Strother, M, 2021)

Context

ExcerptReference
"DPD deficiency has been associated with severe 5-FU toxicity."( Diasio, RB; Ezzeldin, H; Saif, MW; Sellers, S; Vance, K, 2007)

Treatment

ExcerptReference
"The frequency of DPD deficiency was determined by radiochemical methods in the peripheral blood mononuclear cells (PBMCs) of 764 CRC patients treated with 5-FU."( Adleff, V; Budai, B; Hitre, E; Komlósi, V; Kralovánszky, J; Pap, E; Réti, A, 2007)
"Thus, a DPD deficiency could be predicted from 5FU blood concentrations measured after the administration of a test dose of 5FU."( Behnke, D; Hausler, P; Jabschinsky, K; Maring, JG; Schalhorn, A; Schmalenberg, H; Schwabe, W; Terborg, C; van Kuilenburg, AB, 2008)
"Screening for DPD deficiency was performed prior to the beginning of the chemotherapy or radiochemotherapy."( Bagarry-Liegey, D; Blesius, A; Brunet, C; Chefrour, M; Ciccolini, J; Dahan, L; Duffaud, F; Favre, R; Ferri-Dessens, RM; Frances, N; Giovanni, A; Lacarelle, B; Marouani, H; Mercier, C; Seitz, JF; Varoquaux, A; Yang, CG; Zanaret, M, 2011)
"It implies that DPD deficiency can cause neurotoxicity in 5-FU-treated patients and advocates for the prospective screening of DPD deficiency before starting any 5-FU-containing chemotherapy so as to prevent such side effects in the future."( Ciccolini, J; Cordier, PY; Lacarelle, B; Mercier, C; Nau, A; Oliver, M; Peytel, E, 2011)
"Pretherapeutic detection of DPD deficiency could prevent severe toxicity otherwise limiting drug administration."( Carlsson, G; Gustavsson, B; Odin, E; Wettergren, Y, 2012)

Research

Studies (165)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's1 (0.61)12.5806
2000's53 (32.12)18.1394
2010's68 (41.21)28.8240
2020's43 (26.06)9.53
DrugIndicatedRelationship StrengthStudiesTrials
n-carbamoyl-beta-alanine0low10
beta-alanine0low20
carnitine0low20
dihydrouracil0medium141
thymine0low100
uracil0medium472
chloroquine0low10
dapsone0low10
fluorouracil0medium1362
hydralazine0low10
oxonic acid0low30
primaquine0low10
tegafur0low80
thymidine0low10
floxuridine0low50
bromouracil0low10
ethinyl estradiol0low10
uridine0low60
uridine triphosphate0low10
trifluridine0low30
valine0low10
pivalic acid0low10
quinuclidines0low10
thiophenes0low20
quinazolines0low20
pyrimidine0low30
ninhydrin0low10
isosorbide0low10
deoxycytidine0low200
pn 4010low50
camptothecin0low30
phenyl acetate0low50
s-adenosylmethionine0low10
gemcitabine0low10
irinotecan0low20
capecitabine0medium550
3-aminoisobutyric acid0low20
cephalosporin c0low10
uftoral0low10
5-fluorodihydrouracil0low20
gefitinib0low10
drospirenone and ethinyl estradiol combination0low10
erlotinib hydrochloride0low10
flavin-adenine dinucleotide0low10
5-(2-bromovinyl)uracil0low10
terbinafine0low10
bilirubin0low10
ma-10low10
5-fluorouridine 5'-triphosphate0low10
4-sulfophenylmethallyl ether0low10
gimeracil0low10
s 1 (combination)0low30
levoleucovorin0low30
deoxyguanosine0low10
folic acid0low10
raltitrexed0low10
8-hydroxy-2'-deoxyguanosine0low10

Protein Targets (981)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
P2Y purinoceptor 20022
P2Y purinoceptor 40022
Chain A, Avidin0022
Chain A, Avidin0022
Chain B, Avidin0022
Luciferase4004
cytochrome P450 family 3 subfamily A polypeptide 47007
cytochrome P450 2D64004
euchromatic histone-lysine N-methyltransferase 28008
peripheral myelin protein 22100010
Albumin0011
ATP-dependent translocase ABCB10213
Replicase polyprotein 1ab0224
Replicase polyprotein 1ab0224
Reverse transcriptase/RNaseH 0123
Broad substrate specificity ATP-binding cassette transporter ABCG20214
regulator of G-protein signaling 43003
lethal factor (plasmid)2002
Cytochrome P450 3A40404
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Glutamate receptor ionotropic, NMDA 1 0101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0101
Proton-coupled amino acid transporter 10101
Glutamate receptor ionotropic, NMDA 3B0101
Sodium- and chloride-dependent GABA transporter 20101
Glutamate receptor ionotropic, NMDA 3A0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE4004
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, 2-oxoglutarate Oxygenase5005
Chain A, Cruzipain2002
phosphopantetheinyl transferase4004
USP1 protein, partial5005
Microtubule-associated protein tau6006
aldehyde dehydrogenase 1 family, member A17007
vitamin D3 receptor isoform VDRA3003
DNA polymerase kappa isoform 12002
caspase-1 isoform alpha precursor3003
lamin isoform A-delta10120012
Caspase-72002
Inositol monophosphatase 13003
Solute carrier organic anion transporter family member 1B30204
Solute carrier organic anion transporter family member 1B10203
Chain A, Ferritin light chain3003
DNA topoisomerase 0101
thioredoxin reductase8008
15-lipoxygenase, partial2002
ATAD5 protein, partial5005
Fumarate hydratase5005
NFKB1 protein, partial1001
PPM1D protein4004
TDP1 protein140014
Thrombopoietin3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
thyroid stimulating hormone receptor6006
EWS/FLI fusion protein6006
estrogen-related nuclear receptor alpha120012
polyprotein5005
67.9K protein9009
glucocerebrosidase2002
putative alpha-glucosidase1001
alpha-galactosidase3003
Bloom syndrome protein isoform 12002
lysosomal alpha-glucosidase preproprotein3003
peripheral myelin protein 22 isoform 12002
hemoglobin subunit beta2002
cellular tumor antigen p53 isoform a3003
cytochrome P450 2C19 precursor1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
chromobox protein homolog 15005
nuclear factor erythroid 2-related factor 2 isoform 26006
huntingtin isoform 22002
ras-related protein Rab-9A2002
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
serine/threonine-protein kinase mTOR isoform 12002
DNA polymerase iota isoform a (long)4004
nuclear receptor ROR-gamma isoform 14004
geminin100010
survival motor neuron protein isoform d6006
cytochrome P450 3A4 isoform 14004
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 14004
histone acetyltransferase KAT2A isoform 12002
relaxin receptor 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi4004
Telomerase reverse transcriptase0101
Serine/threonine-protein kinase Chk10022
Histone deacetylase 30101
ATP-binding cassette sub-family C member 30909
Multidrug resistance-associated protein 409011
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Bile salt export pump013013
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0001
DNA ligase0202
Interferon beta7007
Integrin beta-33003
Integrin alpha-IIb3003
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 10117
DNA topoisomerase 2-alpha0112
Gamma-aminobutyric acid receptor subunit beta-14004
Gamma-aminobutyric acid receptor subunit delta4004
Gamma-aminobutyric acid receptor subunit gamma-24004
Gamma-aminobutyric acid receptor subunit alpha-54004
Gamma-aminobutyric acid receptor subunit alpha-34004
Gamma-aminobutyric acid receptor subunit gamma-14004
Gamma-aminobutyric acid receptor subunit alpha-24004
Type-2 restriction enzyme BamHI0101
Gamma-aminobutyric acid receptor subunit alpha-44004
Gamma-aminobutyric acid receptor subunit gamma-34004
Gamma-aminobutyric acid receptor subunit alpha-64004
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
5-hydroxytryptamine receptor 2B0202
Type-2 restriction enzyme HindIII0101
D(1A) dopamine receptor1001
Histone deacetylase 40101
Ribonuclease pancreatic0101
Gamma-aminobutyric acid receptor subunit alpha-14004
Gamma-aminobutyric acid receptor subunit beta-34004
Gamma-aminobutyric acid receptor subunit beta-24004
DNA topoisomerase 2-beta0012
DNA topoisomerase 10102
Histone deacetylase 10101
DNA topoisomerase 10101
Integrase 0101
Histone deacetylase 70101
GABA theta subunit4004
Histone deacetylase 20101
Canalicular multispecific organic anion transporter 10909
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit epsilon4004
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
RAR-related orphan receptor gamma8008
estrogen nuclear receptor alpha130013
Liver carboxylesterase 10002
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0123
Replicase polyprotein 1ab0123
glucose-6-phosphate 1-dehydrogenase isoform b0101
flap endonuclease 13003
Transmembrane protease serine 20123
Dihydrofolate reductase 0202
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein1103
Histidine-rich protein PFHRP-II0102
Procathepsin L0123
Muscarinic acetylcholine receptor M20102
Muscarinic acetylcholine receptor M40304
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0303
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Spike glycoprotein0101
Muscarinic acetylcholine receptor M10102
Ribosyldihydronicotinamide dehydrogenase [quinone]0213
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0303
DNA ligase 10101
Muscarinic acetylcholine receptor M30101
Serine/threonine-protein kinase mTOR0213
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10303
Spike glycoprotein81211
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20202
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0202
Ataxin-24004
Sigma non-opioid intracellular receptor 10303
Angiotensin-converting enzyme 2 0123
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase 0101
interleukin 83003
AR protein100010
Smad31001
glucocorticoid receptor [Homo sapiens]8008
retinoid X nuclear receptor alpha8008
G4004
bromodomain adjacent to zinc finger domain 2B1001
peroxisome proliferator-activated receptor delta4004
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
cytochrome P450 2C9 precursor1001
thyroid hormone receptor beta isoform 2100010
Bile salt export pump0202
HLA class I histocompatibility antigen, B alpha chain 4004
Myeloperoxidase0202
Dihydrofolate reductase0303
Histamine H2 receptor4004
5-hydroxytryptamine receptor 60101
Nuclear receptor ROR-gamma3003
Inositol hexakisphosphate kinase 14004
cytochrome P450 2C9, partial4004
Thymidine kinase 2 0101
Deoxycytidine kinase0014
Probable deoxycytidylate deaminase0001
Cytidine deaminase0103
AAA family ATPase 0002
Thymidine kinase, cytosolic0306
AAA family ATPase 0001
Sterol O-acyltransferase 10202
Epidermal growth factor receptor0527
Receptor tyrosine-protein kinase erbB-20213
Serine/threonine-protein kinase B-raf 0101
pregnane X receptor2002
hypoxia-inducible factor 1 alpha subunit2002
GLI family zinc finger 3100010
caspase 7, apoptosis-related cysteine protease3003
estrogen receptor 2 (ER beta)6006
nuclear receptor subfamily 1, group I, member 38008
progesterone receptor5005
retinoic acid nuclear receptor alpha variant 17007
farnesoid X nuclear receptor9009
pregnane X nuclear receptor6006
caspase-33003
IDH15005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
thyroid stimulating hormone receptor2002
activating transcription factor 64004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)4004
thyroid hormone receptor beta isoform a1001
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 18008
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
Vpr2002
Solute carrier family 22 member 20202
Voltage-dependent calcium channel gamma-2 subunit7007
Cytochrome P450 2B10101
Estrogen receptor0213
Glucocorticoid receptor0202
Sex hormone-binding globulin0011
Cellular tumor antigen p53100010
Glycine receptor subunit alpha-10202
Aldo-keto reductase family 1 member B10404
Neuronal acetylcholine receptor subunit alpha-41001
Adenosine receptor A30202
Neuronal acetylcholine receptor subunit beta-21001
Polyunsaturated fatty acid lipoxygenase ALOX150202
Androgen receptor0202
Alpha-1B adrenergic receptor0202
Glutamate receptor 27007
Glycine receptor subunit beta0202
Cytochrome P450 2B60101
UDP-glucuronosyltransferase 1A1 0102
Glycine receptor subunit alpha-20202
Sodium-dependent noradrenaline transporter 0404
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Glycine receptor subunit alpha-30202
Adenosine receptor A2a0202
Sodium-dependent serotonin transporter0404
Mu-type opioid receptor0202
Kappa-type opioid receptor0202
Alpha-1A adrenergic receptor0202
Sulfotransferase 1A10214
Sodium-dependent dopamine transporter 0202
Aldehyde oxidase0101
TAR DNA-binding protein 433003
Nuclear receptor subfamily 1 group I member 3 0101
Multidrug and toxin extrusion protein 20202
Estrogen receptor beta0112
Multidrug and toxin extrusion protein 10202
ATP-dependent phosphofructokinase4004
thioredoxin glutathione reductase1001
Histone H2A.x7007
interferon gamma precursor0002
streptokinase A precursor0011
Sodium/nucleoside cotransporter 20303
Thymidylate synthase0709
Thymidine phosphorylase0205
Solute carrier family 15 member 10101
Thymidine kinase0002
Chain A, Uracil Phosphoribosyltransferase0101
endonuclease IV1001
acetylcholinesterase3003
glp-1 receptor, partial3003
Skn7p0001
nonstructural protein 12002
arylsulfatase A2002
Solute carrier family 22 member 80001
Aromatase0101
ATPase family AAA domain-containing protein 52002
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
acid sphingomyelinase2002
DNA polymerase beta2002
Thymidylate synthase0505
Dihydrofolate reductase0336
Aldo-keto reductase family 1 member B10101
Alpha-synuclein1001
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Leukotriene C4 synthase0011
aryl hydrocarbon receptor2002
Caspase-71001
potassium voltage-gated channel subfamily H member 2 isoform d3003
caspase-31001
epidermal growth factor receptor isoform a precursor1102
tyrosine-protein kinase Yes1001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0112
Serine/threonine-protein kinase PLK40011
Serine/threonine-protein kinase 250011
ATP-dependent RNA helicase DDX3X0011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase RIO30011
Dual specificity mitogen-activated protein kinase kinase 70011
Inhibitor of nuclear factor kappa-B kinase subunit beta0011
Peripheral plasma membrane protein CASK0011
Aurora kinase A0011
Cyclin-G-associated kinase0112
Serine/threonine-protein kinase DCLK10011
Inhibitor of nuclear factor kappa-B kinase subunit alpha0011
Muscle, skeletal receptor tyrosine-protein kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Mitogen-activated protein kinase 130011
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
3-phosphoinositide-dependent protein kinase 10011
Mitogen-activated protein kinase kinase kinase 130011
Death-associated protein kinase 30011
Mitogen-activated protein kinase kinase kinase 70011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
NUAK family SNF1-like kinase 10011
Dynamin-like 120 kDa protein, mitochondrial0011
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0011
Tyrosine-protein kinase JAK20011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0011
Serine/threonine-protein kinase PAK 30011
Cyclin-dependent kinase-like 50011
Serine/threonine-protein kinase 17B0011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Cyclin-dependent kinase 140011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Serine/threonine-protein kinase OSR10011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Serine/threonine-protein kinase Chk20011
Tyrosine-protein kinase ABL10123
RAF proto-oncogene serine/threonine-protein kinase0011
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Cytochrome P450 1A20202
Cytochrome P450 2E10101
Protein kinase C beta type0011
Insulin receptor0112
Tyrosine-protein kinase Lck0011
Tyrosine-protein kinase Fyn0011
Cyclin-dependent kinase 10011
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0011
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0112
Proto-oncogene tyrosine-protein kinase ROS0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Quinolone resistance protein NorA0101
Wee1-like protein kinase 20011
Uncharacterized serine/threonine-protein kinase SBK30011
Serine/threonine-protein kinase A-Raf0011
Cytochrome P450 2C80101
Mast/stem cell growth factor receptor Kit0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
Myosin light chain kinase, smooth muscle0011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0112
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Insulin receptor-related protein0011
Serine/threonine-protein kinase B-raf0112
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Platelet-derived growth factor receptor alpha0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
Vascular endothelial growth factor receptor 1 0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Interferon-induced, double-stranded RNA-activated protein kinase0011
Casein kinase II subunit alpha'0011
Ras-related protein Rab-6A0011
Serine/threonine-protein kinase MAK0011
Cyclin-dependent kinase 11B0011
Ephrin type-A receptor 10011
Fibroblast growth factor receptor 20011
Receptor tyrosine-protein kinase erbB-30112
Multifunctional protein ADE20011
Fibroblast growth factor receptor 40011
Fibroblast growth factor receptor 30011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Sodium-dependent dopamine transporter0112
Protein kinase C eta type0011
Cyclin-dependent kinase 20022
Beta-adrenergic receptor kinase 10011
Cruzipain0101
Probable ATP-dependent RNA helicase DDX60011
Activin receptor type-2A0011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20011
Ephrin type-A receptor 30011
Ephrin type-A receptor 80011
Ephrin type-B receptor 20011
Leukocyte tyrosine kinase receptor0011
Non-receptor tyrosine-protein kinase TYK20112
UMP-CMP kinase 0011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
Tyrosine-protein kinase receptor UFO0011
Mitogen-activated protein kinase 40011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
G protein-coupled receptor kinase 40011
Cytochrome P450 2C190101
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Type-1 angiotensin II receptor0101
Prostaglandin G/H synthase 20011
Tyrosine-protein kinase receptor Tie-10011
Vascular endothelial growth factor receptor 30011
Vascular endothelial growth factor receptor 20112
Dual specificity mitogen-activated protein kinase kinase 20011
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0011
Glycine--tRNA ligase0011
Mitogen-activated protein kinase kinase kinase 80101
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0112
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0112
Megakaryocyte-associated tyrosine-protein kinase0011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase TXK0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase ZAP-700011
Tyrosine-protein kinase SYK0011
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform alpha0112
Casein kinase I isoform delta0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0112
MAP kinase-activated protein kinase 20011
Cyclin-dependent kinase 80011
Elongation factor Tu, mitochondrial0011
Cysteine--tRNA ligase, cytoplasmic0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0011
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Serine/threonine-protein kinase Nek40011
Tyrosine-protein kinase JAK30112
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
Death-associated protein kinase 10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 120011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10011
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40112
Ephrin type-B receptor 10011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Hormonally up-regulated neu tumor-associated kinase0011
Serine/threonine-protein kinase SIK10011
Receptor-interacting serine/threonine-protein kinase 40011
Ras-related protein Rab-100011
Cell division control protein 2 homolog0011
Actin-related protein 30011
Actin-related protein 20011
Calcium-dependent protein kinase 10011
GTP-binding nuclear protein Ran0011
Tubulin alpha-1A chain0011
Casein kinase II subunit alpha0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0011
SRSF protein kinase 20011
Casein kinase I isoform gamma-20011
DNA-dependent protein kinase catalytic subunit0101
Mitogen-activated protein kinase kinase kinase 90011
Serine/threonine-protein kinase PknB0011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase-like 10011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Synaptic vesicular amine transporter0101
Protein kinase C epsilon type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Angiopoietin-1 receptor0011
Mitogen-activated protein kinase kinase kinase 100011
Transcription factor p650101
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0011
Protein kinase C delta type0011
Tyrosine-protein kinase BTK0011
Tyrosine-protein kinase receptor TYRO30011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0011
Myotonin-protein kinase0011
Mitogen-activated protein kinase kinase kinase kinase 20011
Mitogen-activated protein kinase kinase kinase 120011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Serine/threonine-protein kinase PAK 10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
cGMP-dependent protein kinase 20011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase PRP4 homolog0011
Receptor-interacting serine/threonine-protein kinase 10011
Calcium/calmodulin-dependent protein kinase type II subunit beta0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Calcium/calmodulin-dependent protein kinase type 10011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Peroxisomal acyl-coenzyme A oxidase 10011
Serine/threonine-protein kinase D10011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40112
Ribosomal protein S6 kinase alpha-20011
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Rhodopsin kinase GRK10011
NT-3 growth factor receptor0011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
BDNF/NT-3 growth factors receptor0011
Mitogen-activated protein kinase 60011
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Uncharacterized aarF domain-containing protein kinase 50011
Serine/threonine-protein kinase ULK30011
Serine/threonine-protein kinase SBK10011
Mitogen-activated protein kinase kinase kinase 190011
Putative heat shock protein HSP 90-beta 20011
Serine/threonine-protein kinase TNNI3K0011
Leucine-rich repeat serine/threonine-protein kinase 20011
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase Nek50011
Serine/threonine-protein kinase N30011
Serine/threonine-protein kinase ULK30011
Dual serine/threonine and tyrosine protein kinase0011
Mitogen-activated protein kinase kinase kinase 150011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
Serine/threonine-protein kinase tousled-like 20011
Serine/threonine-protein kinase 32C0011
Serine/threonine-protein kinase pim-30011
ATP-dependent RNA helicase DDX420011
Serine/threonine-protein kinase VRK20011
Myosin light chain kinase family member 40011
Homeodomain-interacting protein kinase 10011
Calcium/calmodulin-dependent protein kinase type 1D0011
Mitogen-activated protein kinase kinase kinase kinase 30011
Cyclin-dependent kinase-like 30011
MAP kinase-activated protein kinase 50011
Serine/threonine-protein kinase BRSK20011
Serine/threonine-protein kinase NIM10011
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Serine/threonine-protein kinase ULK20011
Misshapen-like kinase 10011
Serine/threonine-protein kinase DCLK20011
Calcium/calmodulin-dependent protein kinase kinase 10011
Casein kinase I isoform alpha-like0011
Homeodomain-interacting protein kinase 40011
Myosin-IIIa0011
Ankyrin repeat and protein kinase domain-containing protein 10011
Serine/threonine-protein kinase Nek110011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase BRSK10011
Serine/threonine-protein kinase 350011
Serine/threonine-protein kinase Nek70011
Rhodopsin kinase GRK70011
Serine/threonine-protein kinase 32A0011
Myosin-IIIb0011
ATP-dependent RNA helicase DDX10011
Dual specificity tyrosine-phosphorylation-regulated kinase 20011
Cyclin-dependent kinase-like 20011
Mitogen-activated protein kinase kinase kinase kinase 10011
Serine/threonine-protein kinase Sgk30011
Atypical kinase COQ8B, mitochondrial0011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
Cyclin-dependent kinase 150011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
SRSF protein kinase 10011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Serine/threonine-protein kinase RIO10011
MAP kinase-interacting serine/threonine-protein kinase 10011
Serine/threonine-protein kinase RIO20011
Cyclin-dependent kinase 190011
Transient receptor potential cation channel subfamily M member 60011
Testis-specific serine/threonine-protein kinase 10011
Serine/threonine-protein kinase 330011
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
Serine/threonine-protein kinase DCLK30011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
Myosin light chain kinase 2, skeletal/cardiac muscle0011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
Homeodomain-interacting protein kinase 20011
Tyrosine-protein kinase Srms0011
Homeodomain-interacting protein kinase 30011
Serine/threonine-protein kinase PLK30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
MAP kinase-interacting serine/threonine-protein kinase 20011
Serine/threonine-protein kinase Nek60011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
SNF-related serine/threonine-protein kinase0011
Serine/threonine-protein kinase LATS20011
Serine/threonine-protein kinase 360011
Phenylalanine--tRNA ligase beta subunit0011
Isoleucine--tRNA ligase, mitochondrial0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Serine/threonine-protein kinase 32B0011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
Serine/threonine-protein kinase PLK20011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase MARK10011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase PAK 50011
Serine/threonine-protein kinase 260011
eIF-2-alpha kinase GCN20011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
Phosphatidylinositol 4-kinase beta0011
Serine/threonine-protein kinase 17A0011
STE20/SPS1-related proline-alanine-rich protein kinase0011
Ephrin type-A receptor 60011
5'-AMP-activated protein kinase subunit gamma-20011
Serine/threonine-protein kinase TBK10011
Septin-90011
Death-associated protein kinase 20011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase tousled-like 10011
Serine/threonine-protein kinase TAO20011
Long-chain-fatty-acid--CoA ligase 50011
ALK tyrosine kinase receptor0011
SRSF protein kinase 30011
Serine/threonine-protein kinase ICK0011
Cyclin-dependent kinase 11A0011
Aurora kinase C0011
Calcium/calmodulin-dependent protein kinase type II subunit alpha0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase 38-like0011
Microtubule-associated serine/threonine-protein kinase 10011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Chain A, DEOXYNUCLEOSIDE KINASE0101
Equilibrative nucleoside transporter 10303
GLS protein1001
Parkin1001
pyruvate kinase1001
cytochrome P450 2D6 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
muscarinic acetylcholine receptor M11001
pyruvate kinase PKM isoform b1001
N-glycosylase/DNA lyase0101
Ornithine decarboxylase1001
Aspartate aminotransferase, cytoplasmic0101
Lactoperoxidase0101
Single-stranded DNA cytosine deaminase1001
Chain A, Acetylcholinesterase0101
Solute carrier family 22 member 1 0101
Solute carrier family 22 member 30101
Interstitial collagenase0101
Acetylcholinesterase0101
Acetylcholinesterase0203
Thymidine phosphorylase0102
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0202
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX123003
transcriptional regulator ERG isoform 31001
importin subunit beta-1 isoform 11001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0304
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0202
Carbonic anhydrase 20112
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0202
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0202
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0303
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0202
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
SMAD family member 21001
SMAD family member 31001
mitogen-activated protein kinase 11001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Carbonic anhydrase 10101
Carbonic anhydrase 40101
Carbonic anhydrase 70101
Carbonic anhydrase 90101
Histone-lysine N-methyltransferase EHMT20101
Histone-lysine N-methyltransferase EHMT10101
Free fatty acid receptor 30011
90-kda heat shock protein beta HSP90 beta, partial0101
heat shock protein HSP 90-alpha isoform 20101
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] B0101
Serine hydroxymethyltransferase, mitochondrial0101
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Chloroquine resistance transporter0101
Chain A, Thymidylate Synthase0101
Chain B, Thymidylate Synthase0101
Chain A, THYMIDYLATE SYNTHASE0101
Chain A, THYMIDYLATE SYNTHASE0101
Thymidylate synthase 0101
Met repressor 0022
Protein arginine N-methyltransferase 50011
Histone H3K27 methylase0001
Phenylethanolamine N-methyltransferase0012
S-adenosylmethionine decarboxylase proenzyme0102
Protein-L-isoaspartate(D-aspartate) O-methyltransferase0101
Catechol O-methyltransferase0001
Protein arginine N-methyltransferase 10101
Methylosome protein 500011
Chain A, Beta-lactamase1001
cystic fibrosis transmembrane conductance regulator0101
Cytochrome P450 2D60101
C-8 sterol isomerase0101
Squalene monooxygenase 0101
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Thymidine kinase 0203
Thymidine kinase0102
Polyunsaturated fatty acid 5-lipoxygenase0101
Thymidylate kinase0101
Thymidine kinase, cytosolic 0002
Thymidylate kinase0202
Thymidine kinase 0102
Thymidine kinase0001
Thymidine kinase0001
Thymidine phosphorylase0101
LMP1 [Human herpesvirus 4]0001
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
Chain A, Uracil-DNA Glycosylase0101
Protein cereblon0404
Chain A, Cytidine Deaminase0101
Sodium/nucleoside cotransporter 10202
Rap guanine nucleotide exchange factor 31001
Equilibrative nucleoside transporter 20202
Uridine-cytidine kinase 1 0001
Solute carrier family 28 member 30202
P2Y purinoceptor 40011
Thromboxane A2 receptor 0011
N-acetyllactosaminide alpha-1,3-galactosyltransferase0101
P2Y purinoceptor 2 0112
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 60011
RNA-directed RNA polymerase 0001
P2Y purinoceptor 110011
Chain A, Arginase 10101
Large neutral amino acids transporter small subunit 10101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]