Page last updated: 2024-09-28

Dicrocoeliasis

Infection with flukes of the genus Dicrocoelium.

Synonyms(1)

Synonym
Dicrocoeliasis

Research Excerpts

Treatment

ExcerptReference
"The patient was treated for dicrocoeliasis with praziquantel (3 x 600 mg/day for three days)."( Adusu, E; Jelinek, T; Rack, J, 2004)

Research

Studies (65)

TimeframeStudies, This Condition (%)All Conditions %
pre-199027 (41.54)23.3326
1990's9 (13.85)12.5806
2000's15 (23.08)18.1394
2010's11 (16.92)28.8240
2020's3 (4.62)9.53
DrugIndicatedRelationship StrengthStudiesTrials
gamma-aminobutyric acid0low10
carbamates0low40
albendazole0low110
guaifenesin0low10
hexachlorophene0low10
tetramisole0low10
praziquantel0low80
emetine0low10
malondialdehyde0low10
oxyclozanide0low10
cambendazole0low10
triclabendazole0low20
glutathione disulfide0low20
netobimin0low20
luxabendazole0low10
albendazole sulfoxide0low10
retinol0low10
isomethyleugenol0low10
pica0low10
thiophanate0low30
bilirubin0low30
beta carotene0low20
ants0low220
ascorbic acid0low10
agar0low10
vitamin b 120low10

Protein Targets (374)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase1001
Luciferase4004
glp-1 receptor, partial3003
hypoxia-inducible factor 1 alpha subunit3003
RAR-related orphan receptor gamma7007
ATAD5 protein, partial4004
Fumarate hydratase2002
TDP1 protein8008
GLI family zinc finger 35005
AR protein100010
caspase 7, apoptosis-related cysteine protease1001
nuclear receptor subfamily 1, group I, member 36006
progesterone receptor4004
glucocorticoid receptor [Homo sapiens]9009
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha4004
estrogen-related nuclear receptor alpha8008
farnesoid X nuclear receptor5005
pregnane X nuclear receptor9009
estrogen nuclear receptor alpha100010
polyprotein2002
67.9K protein2002
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
caspase-31001
IDH14004
euchromatic histone-lysine N-methyltransferase 27007
aryl hydrocarbon receptor5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
v-jun sarcoma virus 17 oncogene homolog (avian)2002
nuclear receptor subfamily 1, group I, member 25005
Histone H2A.x2002
cellular tumor antigen p53 isoform a2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
chromobox protein homolog 13003
nuclear factor erythroid 2-related factor 2 isoform 24004
transcriptional regulator ERG isoform 33003
thyroid hormone receptor beta isoform 29009
histone deacetylase 9 isoform 33003
heat shock protein beta-13003
mitogen-activated protein kinase 13003
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
geminin9009
Vif0001
peripheral myelin protein 227007
survival motor neuron protein isoform d3003
muscleblind-like protein 1 isoform 12002
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
lamin isoform A-delta107007
neuropeptide S receptor isoform A4004
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40303
Voltage-dependent calcium channel gamma-2 subunit3003
Bile salt export pump0505
Interferon beta4004
Cellular tumor antigen p537007
Integrin beta-31001
Integrin alpha-IIb1001
Methionine aminopeptidase0101
Glutamate receptor 23003
Fatty-acid amide hydrolase 10101
Inositol monophosphatase 13003
Canalicular multispecific organic anion transporter 10303
ATPase family AAA domain-containing protein 55005
Ataxin-25005
cytochrome P450 family 3 subfamily A polypeptide 45005
EWS/FLI fusion protein2002
cytochrome P450 2D63003
nuclear factor erythroid 2-related factor 2 isoform 15005
Chain A, Hyaluronidase, phage associated0101
acetylcholinesterase3003
thioredoxin glutathione reductase1001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
lethal factor (plasmid)2002
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0101
Alpha-2B adrenergic receptor0011
Spike glycoprotein2013
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10001
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0001
Solute carrier family 23 member 10101
aldehyde dehydrogenase 1 family, member A14004
core protein, partial0101
histone acetyltransferase KAT2A isoform 13003
Solute carrier organic anion transporter family member 1B30405
Solute carrier organic anion transporter family member 1B10405
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, 2-oxoglutarate Oxygenase1001
Chain A, Cruzipain3003
phosphopantetheinyl transferase4004
USP1 protein, partial4004
Microtubule-associated protein tau5005
vitamin D3 receptor isoform VDRA3003
DNA polymerase kappa isoform 11001
caspase-1 isoform alpha precursor1001
Caspase-72002
nuclear receptor ROR-gamma isoform 14004
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
NS5 0011
thioredoxin reductase5005
PPM1D protein2002
estrogen receptor 2 (ER beta)4004
Parkin3003
peroxisome proliferator-activated receptor delta3003
activating transcription factor 62002
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor2002
flap endonuclease 13003
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 11001
Transmembrane protease serine 20011
Glucose transporter0101
Serine hydrolase RBBP90101
Hexose transporter 1 0101
Procathepsin L0011
ATP-dependent translocase ABCB10102
Alpha-2A adrenergic receptor0404
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0224
Solute carrier family 2, facilitated glucose transporter member 10101
Alpha-2C adrenergic receptor0404
Hypoxia-inducible factor 1-alpha0102
Dihydroorotate dehydrogenase 0101
Endothelial PAS domain-containing protein 10102
Angiotensin-converting enzyme 2 0011
Chain A, Ferritin light chain2002
Gamma-aminobutyric acid 0011
Gamma-aminobutyric acid receptor subunit rho-30011
Hsf1 protein0011
thyroid stimulating hormone receptor3003
regulator of G-protein signaling 42002
bromodomain adjacent to zinc finger domain 2B2002
arylsulfatase A2002
Bloom syndrome protein isoform 13003
D(1A) dopamine receptor1001
thyroid hormone receptor beta isoform a2002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit pi3205
Gamma-aminobutyric acid receptor subunit delta0101
Histone deacetylase 30101
Gamma-aminobutyric acid type B receptor subunit 20011
Gamma-aminobutyric acid type B receptor subunit 20101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-13205
Gamma-aminobutyric acid receptor subunit alpha-60011
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit delta3205
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-23216
Gamma-aminobutyric acid receptor subunit alpha-53205
Gamma-aminobutyric acid receptor subunit alpha-33205
Gamma-aminobutyric acid receptor subunit gamma-20011
Gamma-aminobutyric acid receptor subunit delta0011
Gamma-aminobutyric acid receptor subunit gamma-13205
Gamma-aminobutyric acid receptor subunit alpha-23205
Sodium- and chloride-dependent GABA transporter 10101
Gamma-aminobutyric acid receptor subunit rho-10022
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit alpha-30011
Gamma-aminobutyric acid receptor subunit gamma-30011
Gamma-aminobutyric acid receptor subunit alpha-43205
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit gamma-33205
Gamma-aminobutyric acid receptor subunit rho-20011
Gamma-aminobutyric acid receptor subunit alpha-63205
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent taurine transporter0101
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-30112
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Gamma-aminobutyric acid receptor subunit alpha-40112
Gamma-aminobutyric acid receptor subunit beta-10011
Histone deacetylase 40101
Gamma-aminobutyric acid receptor subunit alpha-10011
Gamma-aminobutyric acid receptor subunit alpha-13216
Gamma-aminobutyric acid receptor subunit beta-33205
Gamma-aminobutyric acid receptor subunit beta-30011
Gamma-aminobutyric acid receptor subunit beta-23216
Gamma-aminobutyric acid receptor subunit epsilon0101
4-aminobutyrate aminotransferase, mitochondrial0001
4-aminobutyrate aminotransferase, mitochondrial0001
TAR DNA-binding protein 433003
Histone deacetylase 10101
Gamma-aminobutyric acid receptor subunit alpha-60112
Sterol O-acyltransferase 10011
Proton-coupled amino acid transporter 10101
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit pi0011
Histone deacetylase 70101
GABA theta subunit3205
Histone deacetylase 20101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Gamma-aminobutyric acid receptor subunit gamma-30101
Histone deacetylase 80101
Gamma-aminobutyric acid receptor subunit alpha-40011
Gamma-aminobutyric acid receptor subunit epsilon3205
Platelet glycoprotein VI0011
Gamma-aminobutyric acid receptor subunit theta0011
Sodium- and chloride-dependent GABA transporter 20101
Gamma-aminobutyric acid receptor subunit gamma-10011
Histone deacetylase 60101
Gamma-aminobutyric acid type B receptor subunit 10011
Histone deacetylase 90101
Gamma-aminobutyric acid receptor subunit theta0101
Histone deacetylase 50101
Gamma-aminobutyric acid type B receptor subunit 10101
Glutathione reductase0001
Multidrug resistance-associated protein 1 0001
Histone-lysine N-methyltransferase EHMT20101
Histone-lysine N-methyltransferase EHMT10101
SMAD family member 24004
SMAD family member 34004
Rap guanine nucleotide exchange factor 32002
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
calpain II, partial0101
PAX80001
SUMO-10101
15-lipoxygenase, partial2002
pregnane X receptor2002
Mcl-10101
Valosin-containing protein0101
TSHR protein1001
Estrogen receptor 10101
Smad32002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
PINK12002
envelope glycoprotein0101
nonstructural protein 11001
G1001
heat shock protein 900011
heat shock 70kDa protein 1A0101
thyroid stimulating hormone receptor2002
thyrotropin-releasing hormone receptor2002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
Caspase-71001
galactokinase1001
tumor necrosis factor1001
polyunsaturated fatty acid lipoxygenase ALOX121001
neuropeptide Y receptor type 10011
neuropeptide Y receptor type 20011
small ubiquitin-related modifier 2 isoform b precursor0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
caspase-31001
estrogen receptor beta isoform 10101
huntingtin isoform 21001
DNA polymerase beta1001
enteropeptidase precursor1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
fatty acid synthase0101
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase PLK11001
heat shock protein HSP 90-alpha isoform 20002
DNA polymerase eta isoform 11001
heat shock cognate 71 kDa protein isoform 10101
DNA polymerase iota isoform a (long)2002
eukaryotic translation initiation factor 4E isoform 10101
Vpr2002
cytochrome P450 3A4 isoform 13003
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
replicative DNA helicase0001
recombinase A0011
streptokinase A precursor0022
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
POsterior Segregation0011
heat shock cognate 71 kDa protein isoform 20101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
5-hydroxytryptamine receptor 40202
Epidermal growth factor receptor0101
Urokinase-type plasminogen activator0101
Tissue-type plasminogen activator0101
HLA class I histocompatibility antigen, B alpha chain 1001
Receptor tyrosine-protein kinase erbB-20101
Plasminogen activator inhibitor 10101
Cytochrome P450 1A20101
Estrogen receptor0022
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Urokinase-type plasminogen activator0101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Muscarinic acetylcholine receptor M50101
60 kDa chaperonin0101
Adenosine receptor A30202
60 kDa heat shock protein, mitochondrial0101
Muscarinic acetylcholine receptor M20101
Endoplasmic reticulum chaperone BiP0202
Macrophage migration inhibitory factor0202
Androgen receptor0202
Alpha-1B adrenergic receptor0202
Substance-K receptor0202
Acetylcholinesterase0101
Sodium-dependent noradrenaline transporter 0011
Thromboxane-A synthase 0101
Adenosine receptor A11001
Mitogen-activated protein kinase 3 0101
5-hydroxytryptamine receptor 2C0202
Mitogen-activated protein kinase 10101
Adenosine receptor A2a0202
Sodium-dependent serotonin transporter0202
Cytochrome P450 2C190101
Prostaglandin G/H synthase 20101
Alpha-synuclein2103
5-hydroxytryptamine receptor 2B0202
Alpha-1A adrenergic receptor0202
Histamine H2 receptor1001
Nuclear receptor ROR-gamma2002
10 kDa heat shock protein, mitochondrial0101
Mitogen-activated protein kinase 140101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
Estrogen receptor beta0022
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
10 kDa chaperonin 0101
N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D0101
Rap guanine nucleotide exchange factor 42002
Inositol hexakisphosphate kinase 11001
Zinc finger protein mex-50011
cytochrome P450 2C9, partial1001
phosphoglycerate kinase1001
heat shock protein 90, putative0002
M1-family alanyl aminopeptidase0101
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
BZLF20101
large T antigen0101
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0011
M-phase phosphoprotein 81001
muscarinic acetylcholine receptor M11001
Bile salt export pump0101
ATP-dependent phosphofructokinase2002
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
interleukin 81001
potassium voltage-gated channel subfamily H member 2 isoform d2002
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Disintegrin and metalloproteinase domain-containing protein 171001
hepatitis C virus polyprotein1001
alpha-galactosidase1001
Transthyretin0101
Cruzipain0101
Guanine nucleotide-binding protein G1001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]