Diarrheogenic Islet Cell Tumor

A tumor that secretes VASOACTIVE INTESTINAL PEPTIDE, a neuropeptide that causes VASODILATION; relaxation of smooth muscles; watery DIARRHEA; HYPOKALEMIA; and HYPOCHLORHYDRIA. Vipomas, derived from the pancreatic ISLET CELLS, generally are malignant and can secrete other hormones. In most cases, Vipomas are located in the PANCREAS but can be found in extrapancreatic sites.

Synonym
Vipoma Syndrome
WDHA Syndrome
Verner-Morrison Syndrome
WDHH
Pancreatic Cholera
Diarrheogenic Islet Cell Tumor
Pancreatic VIPoma
Vasoactive Intestinal Peptide-Producing Tumor
Vasoactive Intestinal Peptide (VIP) Tumor
Vipoma
Diarrheogenic Tumor
VIP-Secreting Tumor (VIPoma)
Watery Diarrhea Syndrome
Watery Diarrhea with Hypokalemic Alkalosis
Watery Diarrhea, Hypokalemia, and Achlorhydria Syndrome
WDHA

Excerpt	Reference
"Vipomas are tumours which secrete vasoactive intestinal peptide (VIP) and present with severe watery diarrhoea (the Verner and Morrison syndrome)."	( Dupont, C, 1984)
"The diagnosis of VIPoma is simple but localization can be very difficult."	( Bierła, J; Cichy, W; Dobrzańska, A; Rowecka, K; Socha, J; Stodulski, J; Woźniewicz, B, 1984)
"VIPomas are malignant and require sophisticated diagnostic and localization techniques in order to identify their presence."	( O'Dorisio, MS; O'Dorisio, TM; Park, SK, 1996)
"Pancreatic vipoma is an unusual endocrine tumour, with only 5 cases reported in our country."	( Bermejo, F; García López, JL; Gisbert, JP; González Palacios, F; Moreira, V; Moreno, L, 1999)
"The VIPoma syndrome is rare."	( Barbier, JP; Berger, A; Carnot, F; Cellier, C; Cuillerier, E; Haddad, C; Landi, B; Siauve, N; Yaghi, C, 2000)
"A vipoma is a rare differential diagnosis of secretory diarrhoea."	( Höbling, W; Kirchgatterer, A; Knoflach, P; Rammer, M; Stockhammer, M, 2003)
"Vipoma is a rare neuroendocrine tumor most frequently localized in the pancreas."	( Ajmi, S; Ben Ali, A; Ben Hadj Hamida, R; Dahmene, Y; Derbel, F; Gressens, P; Hachicha, I; Henin, D; Korbi, S; Letaief, R; Mnif Hachicha, L; Mokni, M; Zayene, A, 2003)
"VIPoma is rare."	( Fang, HQ; Li, JT; Liu, YB; Peng, CH; Peng, SY; Qian, HR; Wang, XB; Wu, YL, 2004)
"VIPoma is rare."	( Fang, HQ; Ji, C; Li, JT; Liu, YB; Peng, SY; Qian, HR; Tang, Z; Wang, XB; Wu, YL, 2004)
"VIPomas are rare pancreatic endocrine tumors associated with a well-defined clinical syndrome characterized by watery diarrhea, hypokalemia, and metabolic acidosis."	( Cameron, JL; Chojnacki, KA; Ghaferi, AA; Long, WD; Yeo, CJ, 2008)
"VIPomas are rare neuroendocrine tumours, with metastases often confined to the liver."	( Ardill, JE; Johnston, BT; Johnston, PC; Mc Cance, DR, 2010)
"VIPoma is an exceedingly unusual neuroendocrine neoplasm that autonomously secretes vasoactive intestinal polypeptide (VIP)."	( Abu-Zaid, A; Abudan, Z; Algouhi, A; Almana, H; Amin, T; Azzam, A, 2014)
"VIPomas are rare-functioning neuroendocrine tumors (NETs)."	( Brixi, H; Cadiot, G; de Mestier, L; Lombard-Bohas, C; Walter, T, 2015)
"VIPoma is a rare subtype of pancreatic neuroendocrine tumor that can secrete dopamine and can be associated with thromboembolism."	( Freedman, EM; Kebebew, E; Nilubol, N; Patel, D; Quezado, MM, 2016)
"VIPomas are neuroendocrine tumors that autonomously secrete vasoactive intestinal peptide (VIP)."	( Belei, OA; Boeriu, E; Boia, ES; Cerbu, S; Heredea, ER; Iacob, D; Iacob, ER; Marcovici, TM; Mărginean, O; Motoc, AGM, 2017)
"VIPomas are generally rare functioning pancreatic neuroendocrine tumors (PanNETs) that cause watery diarrhea, hypokalemia, and achlorhydria."	( Fujimori, N; Ito, T; Matsumoto, K; Murakami, M; Ogawa, Y; Ohno, A; Oono, T; Takamatsu, Y; Takeno, A; Teramatsu, K; Ueda, K, 2022)

Excerpt	Reference
"A 43-yr-old-man with metastatic VIPoma in whom the conventional measures of surgery, chemotheraphy, and hepatic artery embolization ultimately failed to control his severe diarrhea, resulting from vasoactive intestinal polypeptide hypersecretion, was treated with a new long-acting somatostatin analogue, SMS 201-995, for 14 mo."	( Bloom, SR; Carr, DH; Ch'ng, JL; Kraenzlin, ME; Wood, SM, 1985)
"Two patients with therapy-resistant pancreatic cholera syndrome were successfully treated with human leucocyte interferon given intramuscularly in a dose of 3 X 10(6)-6 X 10(6) IU per day."	( Alm, G; Lindström, H; Lundqvist, G; Oberg, K, 1985)
"Morbidity and mortality from untreated WDHA syndrome are related to long-standing dehydration and electrolyte and acid-base disturbances resulting in chronic renal failure."	( Grier, JF, 1995)
"Liver transplantation for metastatic VIPomas confined to the liver may be justified in selected patients to provide symptomatic hormonal control and pain from tumour bulk, provided there is no extra hepatic disease and medical treatment has been exhausted."	( Ardill, JE; Johnston, BT; Johnston, PC; Mc Cance, DR, 2010)
"We report a successful treatment of VIPoma with hepatic chemoembolization of a metastatic hepatic lesion evidenced by a reduction of VIP levels and resolutions of symptoms in a patient with pancreatic VIPoma unresponsive to increased doses of an octreotide analog."	( Mitchell, K; Saif, MW; Shaib, W, 2010)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	71 (41.04)	23.3326
1990's	37 (21.39)	12.5806
2000's	33 (19.08)	18.1394
2010's	21 (12.14)	28.8240
2020's	11 (6.36)	9.53

Drug	Relationship Strength	Studies	Trials
citric acid, anhydrous	medium	1	1
hydrogen carbonate	low	1	0
iodine	low	1	0
hydroxyindoleacetic acid	medium	2	2
diatrizoic acid	low	1	0
theophylline	low	1	0
verapamil	low	1	0
fluorouracil	low	5	0
indomethacin	low	1	0
iopanoic acid	low	1	0
1-methyl-3-isobutylxanthine	low	1	0
lomustine	low	1	0
loperamide	low	1	0
ondansetron	low	1	0
temozolomide	low	1	0
prednisolone	low	5	0
carbachol	low	1	0
prednisone	low	1	0
leucine	low	1	0
colchicine	low	1	0
egtazic acid	low	1	0
pyrroles	low	2	0
meglumine	low	1	0
gadolinium	low	1	0
chlorine	low	1	0
tetradecanoylphorbol acetate	low	1	0
substance p	low	2	0
enkephalin, methionine	low	1	0
capecitabine	low	1	0
gadolinium 1,4,7,10-tetraazacyclododecane-n,n',n'',n'''-tetraacetate	low	1	0
atropine	low	1	0
dactinomycin	low	2	0
succimer	low	1	0
su 11248	low	3	0
bismuth	low	2	0
pentagastrin	low	1	0
pasireotide	low	1	0
calcimycin	low	1	0
calcitonin	low	1	0
cholecystokinin	low	3	0
ceruletide	low	1	0
gastrins	low	8	0
glucagon	low	4	0
neuropeptide y	low	1	0
peptide phi	low	7	0
c-peptide	low	1	0
bismuth subsalicylate	low	2	0
technetium tc 99m sestamibi	low	2	0
neurotensin	low	7	0
piperidines	low	1	0
vasoactive intestinal peptide	medium	131	1
salicylates	low	2	0
gallium ga 68 dotatate	low	3	0
technetium tc 99m medronate	low	1	0
lutetium lu 177 dotatate	low	1	0
technetium tc 99m dimercaptosuccinic acid	low	1	0
68ga-dotanoc	low	1	0
dacarbazine	low	1	0

Protein Targets (1,134)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Chain A, Phosphodiesterase 9A	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	3	0	0	3
Chain A, Class I phosphodiesterase PDEB1	0	1	0	1
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera	0	1	0	1
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera	0	1	0	1
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
glp-1 receptor, partial	4	0	0	4
thyroid stimulating hormone receptor	7	0	0	7
estrogen-related nuclear receptor alpha	14	0	0	14
Phosphodiesterase	0	3	0	3
mitogen-activated protein kinase 1	2	0	0	2
geminin	10	0	0	10
cytochrome P450 3A4 isoform 1	4	0	0	4
histone acetyltransferase KAT2A isoform 1	3	0	0	3
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
Gamma-aminobutyric acid receptor subunit pi	4	2	0	6
Monocarboxylate transporter 4	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
Renin	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	2	0	6
Gamma-aminobutyric acid receptor subunit delta	4	2	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	4	2	0	6
Gamma-aminobutyric acid receptor subunit alpha-5	4	2	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	4	2	0	6
Gamma-aminobutyric acid receptor subunit gamma-1	4	3	0	7
Gamma-aminobutyric acid receptor subunit alpha-2	4	2	0	6
Adenosine receptor A1	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-4	4	2	0	6
Gamma-aminobutyric acid receptor subunit gamma-3	4	2	0	6
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	2	2	6
Adenosine receptor A2b	0	1	0	3
Adenosine receptor A2b	0	3	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	4	2	0	6
Adenosine receptor A1	0	2	2	8
Adenosine receptor A2a	0	4	0	6
Sodium-dependent serotonin transporter	0	1	0	1
Adenosine receptor A2a	0	2	0	2
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	4	2	0	6
Gamma-aminobutyric acid receptor subunit beta-3	4	2	0	6
Gamma-aminobutyric acid receptor subunit beta-2	4	2	0	6
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Phosphodiesterase	0	1	0	1
GABA theta subunit	4	2	0	6
Phosphodiesterase	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	4	2	0	6
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
GLI family zinc finger 3	11	0	0	11
AR protein	13	0	0	13
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
glucocorticoid receptor [Homo sapiens]	15	0	0	15
retinoid X nuclear receptor alpha	9	0	0	9
pregnane X nuclear receptor	10	0	0	10
cystic fibrosis transmembrane conductance regulator	0	1	0	1
DNA polymerase beta	1	0	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
Solute carrier family 22 member 1	0	6	0	6
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	12
5-hydroxytryptamine receptor 4	0	4	0	4
Bile salt export pump	0	14	0	14
Muscarinic acetylcholine receptor M2	0	4	3	11
Muscarinic acetylcholine receptor M4	0	4	3	10
Muscarinic acetylcholine receptor M1	0	5	2	11
Muscarinic acetylcholine receptor M3	0	5	2	10
Muscarinic acetylcholine receptor M4	0	4	1	8
Muscarinic acetylcholine receptor M5	0	4	1	8
Muscarinic acetylcholine receptor M5	0	4	3	10
Muscarinic acetylcholine receptor M2	0	5	1	10
Muscarinic acetylcholine receptor M1	0	4	3	11
Muscarinic acetylcholine receptor M1	0	1	1	3
Muscarinic acetylcholine receptor M3	0	4	3	10
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	4	0	4
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	4	0	0	6
5-hydroxytryptamine receptor 7	0	4	0	4
Reverse transcriptase/RNaseH	0	1	0	2
Muscarinic acetylcholine receptor	0	3	1	4
Canalicular multispecific organic anion transporter 1	0	12	0	12
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	4	0	0	4
Luciferase	7	0	0	7
euchromatic histone-lysine N-methyltransferase 2	11	0	0	11
lamin isoform A-delta10	10	0	0	10
Spike glycoprotein	6	0	1	7
Chain A, Putative fructose-1,6-bisphosphate aldolase	4	0	0	4
Chain A, ATP-DEPENDENT DNA HELICASE Q1	2	0	0	2
Chain A, Ferritin light chain	3	0	0	3
Chain A, Cruzipain	3	0	0	3
acid sphingomyelinase	1	0	0	1
endonuclease IV	5	0	0	5
thioredoxin reductase	6	0	0	6
ClpP	1	0	0	1
electroneutral potassium-chloride cotransporter KCC2	0	0	1	1
ATAD5 protein, partial	5	0	0	5
Fumarate hydratase	3	0	0	3
USP1 protein, partial	6	0	0	6
GLS protein	4	0	0	4
TDP1 protein	14	0	0	14
Microtubule-associated protein tau	5	0	0	5
TSHR protein	1	0	0	1
Smad3	3	0	0	3
apical membrane antigen 1, AMA1	1	0	0	1
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
regulator of G-protein signaling 4	3	0	0	3
nonstructural protein 1	2	0	0	2
polyprotein	3	0	0	3
67.9K protein	4	0	0	4
glucocerebrosidase	4	0	0	4
Parkin	2	0	0	2
arylsulfatase A	5	0	0	5
LacZ protein (plasmid)	0	0	1	1
XBP1	0	1	0	1
IDH1	6	0	0	6
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
serine-protein kinase ATM isoform a	1	0	0	1
Bloom syndrome protein isoform 1	4	0	0	4
lysosomal alpha-glucosidase preproprotein	2	0	0	2
hexokinase-4 isoform 1	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
peripheral myelin protein 22 isoform 1	5	0	0	5
type-1 angiotensin II receptor	0	1	0	1
D(1A) dopamine receptor	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
vitamin D3 receptor isoform VDRA	6	0	0	6
chromobox protein homolog 1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	5	0	0	5
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	3	0	0	3
glucokinase regulatory protein	1	0	0	1
huntingtin isoform 2	6	0	0	6
flap endonuclease 1	3	0	0	3
ras-related protein Rab-9A	4	0	0	4
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
serine/threonine-protein kinase PLK1	1	0	0	1
apelin receptor	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
DNA damage-inducible transcript 3 protein	0	1	0	1
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
nuclear receptor ROR-gamma isoform 1	6	0	0	6
Vpr	2	0	0	2
survival motor neuron protein isoform d	5	0	0	5
streptokinase A precursor	0	0	1	1
neuropeptide S receptor isoform A	4	0	0	4
Rap guanine nucleotide exchange factor 3	1	0	0	1
Amyloid-beta precursor protein	2	0	0	2
Alpha-synuclein	1	0	0	1
D(1A) dopamine receptor	2	0	0	2
Guanine nucleotide-binding protein G	3	0	0	3
TAR DNA-binding protein 43	3	0	0	3
Ataxin-2	7	0	0	7
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
heat shock protein 90, putative	0	0	0	1
ATP-dependent phosphofructokinase	4	0	0	4
RAR-related orphan receptor gamma	13	0	0	13
estrogen nuclear receptor alpha	16	0	0	16
Liver carboxylesterase 1	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	6	0	0	6
Chain A, Beta-lactamase	2	0	0	2
acetylcholinesterase	4	0	0	4
GALC protein	1	0	0	1
peroxisome proliferator activated receptor gamma	11	0	0	11
thyroid stimulating hormone receptor	5	0	0	5
thyrotropin-releasing hormone receptor	1	0	0	1
v-jun sarcoma virus 17 oncogene homolog (avian)	8	0	0	8
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	3	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Delta-type opioid receptor	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, Proto-oncogene Tyrosine-protein Kinase Src	0	1	0	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase	0	0	1	1
farnesoid X nuclear receptor	6	0	0	6
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	1	0	1
thyroid hormone receptor beta isoform a	4	0	0	4
perilipin-1	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
Beta-lactamase	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	2	1	3
3-dehydroquinate dehydratase	0	0	1	1
ATP-citrate synthase	0	0	0	1
Ribonuclease T	0	0	0	1
Cell death-related nuclease 4	0	0	0	1
3-dehydroquinate dehydratase	0	0	1	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
interleukin 8	5	0	0	5
PAX8	0	0	0	1
pregnane X receptor	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
PPM1D protein	3	0	0	3
Thrombopoietin	3	0	0	3
estrogen receptor 2 (ER beta)	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	9	0	0	9
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
peroxisome proliferator-activated receptor delta	5	0	0	5
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
aryl hydrocarbon receptor	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	7	0	0	7
activating transcription factor 6	6	0	0	6
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
cytochrome P450 2D6 isoform 1	3	0	0	3
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cellular tumor antigen p53 isoform a	2	0	0	2
cytochrome P450 2C19 precursor	1	0	0	1
cytochrome P450 2C9 precursor	3	0	0	3
thyroid hormone receptor beta isoform 2	9	0	0	9
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
steroidogenic factor 1	0	1	0	1
peripheral myelin protein 22	7	0	0	7
muscleblind-like protein 1 isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
lethal factor (plasmid)	2	0	0	2
Solute carrier family 22 member 3	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	7	0	0	7
Interferon beta	8	0	0	8
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	1
Tubulin beta-4A chain	0	2	2	5
Cellular tumor antigen p53	8	0	0	8
ATP-dependent translocase ABCB1	0	2	0	2
Tubulin beta chain	0	2	2	5
ATP-dependent translocase ABCB1	0	5	1	16
Cytochrome P450 3A4	0	3	0	3
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	1	2
Glutamate receptor 2	7	0	0	7
ATP-dependent translocase ABCB1	0	2	0	3
Nuclear receptor ROR-gamma	5	0	0	5
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	0	0	1
ATPase family AAA domain-containing protein 5	5	0	0	5
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
cytochrome P450 2D6	5	0	0	5
Matrix metalloproteinase-9	0	1	0	1
Inositol monophosphatase 1	3	0	0	3
Isocitrate lyase	0	1	0	1
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
15-lipoxygenase, partial	2	0	0	2
caspase 7, apoptosis-related cysteine protease	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
progesterone receptor	8	0	0	8
caspase-3	2	0	0	2
RAD51	0	1	0	1
Histone H2A.x	2	0	0	2
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1	0	1	0	1
Caspase-7	1	0	0	1
Growth factor receptor-bound protein 2	0	1	0	1
Pantothenate synthetase	0	1	0	1
Discoidin domain-containing receptor 2	0	1	1	2
Growth factor receptor-bound protein 2	0	1	0	1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase	0	0	1	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
EWS/FLI fusion protein	7	0	0	7
hemoglobin subunit beta	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Epidermal growth factor receptor	0	3	1	4
Thymidylate synthase	0	1	0	1
Aromatase	0	2	0	2
Carbonic anhydrase 1	0	2	0	2
Carbonic anhydrase 2	0	2	0	2
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
NFKB1 protein, partial	1	0	0	1
hypothetical protein, conserved	1	0	0	1
alpha-galactosidase	1	0	0	1
M-phase phosphoprotein 8	2	0	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
G	4	0	0	4
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	1	0	0	1
heat shock protein beta-1	1	0	0	1
DNA polymerase kappa isoform 1	5	0	0	5
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Prostaglandin G/H synthase 2	0	1	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Albumin	0	1	2	3
Prostaglandin G/H synthase 1	0	2	0	3
Procathepsin L	0	1	1	2
Interleukin-8	0	1	0	1
Androgen receptor	0	2	1	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Caspase-1	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	1
Substance-P receptor	0	2	0	2
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	3	1	5
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	3	2	5
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Sigma intracellular receptor 2	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Inositol hexakisphosphate kinase 1	4	0	0	4
Multidrug and toxin extrusion protein 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	4	0	4
cytochrome P450 2C9, partial	4	0	0	4
histone deacetylase 9 isoform 3	1	0	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	3	0	3
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	2	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
Menin	0	1	0	1
Cocaine esterase	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Transmembrane protease serine 2	0	0	1	1
Beta-2 adrenergic receptor	0	2	0	2
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Replicase polyprotein 1ab	0	3	1	4
Cytochrome P450 2D6	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	1	0	1
Histamine H2 receptor	0	4	0	4
Sodium-dependent serotonin transporter	0	4	0	4
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	4	0	4
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	2	0	2
Nociceptin receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	6	0	6
Calmodulin	0	1	1	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Mu-type opioid receptor	0	1	1	2
Angiopoietin-1 receptor	0	1	2	3
Sodium channel protein type 5 subunit alpha	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	2	0	2
Angiotensin-converting enzyme 2	0	0	1	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
Neurotensin receptor type 1	0	0	1	1
Neurotensin receptor type 2	0	1	1	3
Myelin basic protein	0	0	1	1
Neurotensin receptor type 1	0	1	1	2
Neurotensin receptor type 1	0	2	2	5
Neurotensin receptor type 2	0	2	1	3
Sortilin	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	1	3
Solute carrier family 22 member 2	0	1	0	1
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	1	3
Integrin beta-3	0	1	0	1
Integrin alpha-IIb	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
D	0	1	0	1
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Interleukin-6 receptor subunit alpha	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
Cholecystokinin receptor type A	0	2	0	2
Gastrin/cholecystokinin type B receptor	0	1	1	2
D(4) dopamine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	1	3
Alpha-1A adrenergic receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
5-hydroxytryptamine receptor 6	0	0	0	1
D(2) dopamine receptor	0	2	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Thyrotropin-releasing hormone receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Glycine receptor subunit alpha-4	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	1	3
Multidrug and toxin extrusion protein 2	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	1	3
Histamine H3 receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Nischarin	0	1	0	1
interferon gamma precursor	0	0	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	1	2
luciferase	0	0	0	1
Fatty acid-binding protein, liver	0	1	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	4	2	11
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Cytochrome P450 2C9	0	2	0	2
Glutamine synthetase	0	0	1	1
Androgen receptor	0	1	0	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Cytochrome P450 2J2	0	2	0	2
Estrogen receptor beta	0	2	0	2
thioredoxin glutathione reductase	1	0	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Serine/threonine-protein kinase PLK4	0	1	1	2
Serine/threonine-protein kinase 25	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Serine/threonine-protein kinase Chk1	0	1	1	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Aurora kinase A	0	1	1	2
Cyclin-G-associated kinase	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
NUAK family SNF1-like kinase 1	0	1	1	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	2	2
Cyclin-dependent kinase 14	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	2	1	3
Serine/threonine-protein kinase Chk2	0	1	1	2
Tyrosine-protein kinase ABL1	0	2	2	4
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	1	1	2
Receptor tyrosine-protein kinase erbB-2	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Protein kinase C beta type	0	1	2	3
Insulin receptor	0	1	1	2
Tyrosine-protein kinase Lck	0	1	1	2
Tyrosine-protein kinase Fyn	0	0	1	1
Cyclin-dependent kinase 1	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	1	1	2
Tyrosine-protein kinase HCK	0	1	1	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Platelet-derived growth factor receptor beta	0	3	1	4
Tyrosine-protein kinase Fgr	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	3	1	4
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	2	2
Fibroblast growth factor receptor 1	0	1	1	2
DNA topoisomerase 2-alpha	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Platelet-derived growth factor receptor alpha	0	2	1	3
Translocator protein	0	1	0	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
Vascular endothelial growth factor receptor 1	0	2	1	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Casein kinase II subunit alpha'	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Ephrin type-A receptor 1	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
Acetylcholinesterase	0	1	0	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Ribosomal protein S6 kinase beta-1	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Protein kinase C eta type	0	0	2	2
Cyclin-dependent kinase 2	0	1	1	2
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	0	1
Activin receptor type-2A	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	1	1	2
Mitogen-activated protein kinase 4	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	1	1	2
RAC-beta serine/threonine-protein kinase	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
G protein-coupled receptor kinase 5	0	1	0	1
Myosin-10	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	2	1	3
Vascular endothelial growth factor receptor 2	0	3	1	4
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	1	1	3
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Serine/threonine-protein kinase mTOR	0	1	1	2
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ABL2	0	1	1	2
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	1	1	2
Casein kinase I isoform delta	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	1	3
MAP kinase-activated protein kinase 2	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Glycogen synthase kinase-3 beta	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Ribosomal protein S6 kinase alpha-3	0	1	1	2
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek2	0	1	1	2
Serine/threonine-protein kinase Nek3	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase PLK1	0	2	1	3
Death-associated protein kinase 1	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	1	2
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	1	1	2
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Protein delta homolog 1	0	1	1	2
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C epsilon type	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	1	1	2
Protein kinase C zeta type	0	0	2	2
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	1	2
Serine/threonine-protein kinase PAK 1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Serine/threonine-protein kinase ATR	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Cyclin-dependent kinase 10	0	0	1	1
Serine/threonine-protein kinase D1	0	0	2	2
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	1	1	2
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
AP2-associated protein kinase 1	0	1	1	2
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Rab-like protein 3	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	1	2
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Aurora kinase B	0	1	1	2
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	1	1	2
dCTP pyrophosphatase 1	0	0	1	1
Bromodomain-containing protein 9	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	1	1	2
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase PLK2	0	1	1	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	1	1	2
Serine/threonine-protein kinase 26	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	1	1	2
Septin-9	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	1	1	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	2	1	3
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	2	0	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
polyadenylate-binding protein 1	0	1	0	1
Carbonic anhydrase 12	0	1	0	1
Carbonic anhydrase 9	0	1	0	1
Protein kinase C gamma type	0	1	1	2
Luciferin 4-monooxygenase	0	0	1	1
Ras guanyl-releasing protein 3	0	0	1	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
phosphopantetheinyl transferase	1	0	0	1
transcriptional regulator ERG isoform 3	1	0	0	1
Potassium channel subfamily K member 2	0	0	1	1
Adenosine receptor A3	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A1	0	2	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Bile salt export pump	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Alpha-2A adrenergic receptor	0	2	0	2
Cytochrome P450 2C8	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Diarrheogenic Islet Cell Tumor

Synonyms(16)

Research Excerpts

Overview

Treatment

Research

Studies (173)

Protein Targets (1,134)

Diarrheogenic Islet Cell Tumor

Synonyms(16)

Research Excerpts

Overview

Treatment

Research

Studies (173)

Drugs Studied (68)

Protein Targets (1,134)