Dejerine-Thomas Syndrome

A group of inherited and sporadic disorders which share progressive ataxia in combination with atrophy of the CEREBELLUM; PONS; and inferior olivary nuclei. Additional clinical features may include MUSCLE RIGIDITY; NYSTAGMUS, PATHOLOGIC; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; and OPHTHALMOPLEGIA. The familial form has an earlier onset (second decade) and may feature spinal cord atrophy. The sporadic form tends to present in the fifth or sixth decade, and is considered a clinical subtype of MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085)

Synonyms(12)

Synonym
Olivopontocerebellar Degeneration
Pontoolivocerebellar Atrophy
Olivo-Ponto-Cerebellar Atrophy
Olivo-Ponto-Cerebellar Degeneration
Olivopontocerebellar Atrophies
Olivopontocerebellar Atrophy
Olivopontocerebellar Atrophy, Idiopathic
Familial Olivopontocerebellar Atrophy
Dejerine-Thomas Syndrome
Inherited Olivopontocerebellar Atrophy
Nonfamilial Olivopontocerebellar Atrophy
Presenile Ataxia

Research Excerpts

Overview

Excerpt	Reference
"Infantile olivopontocerebellar atrophies are rare progressive, fatal, neurologic conditions characterized pathologically by loss of neurons and gliosis in the cerebellum, pons, and inferior olivary nuclei in early life."	( Bawle, EV; Becker, CJ; D'Amato, CJ; Hicks, S; Kupsky, WJ, 1995)
"Olivopontocerebellar atrophy is a rare neurodegenerative syndrome associated with 2 distinct disorders: multiple system atrophy and spinocerebellar ataxia."	( Brenner, AI; Finkelstein, M; Harfouch, N; Raden, M; Sathe, S, 2020)

Research

Studies (147)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	20 (13.61)	23.3326
1990's	92 (62.59)	12.5806
2000's	19 (12.93)	18.1394
2010's	10 (6.80)	28.8240
2020's	6 (4.08)	9.53

Drug	Relationship Strength	Studies	Trials
gamma-aminobutyric acid	low	2	0
choline	medium	2	1
creatine	medium	1	1
cytosine	low	1	0
lactic acid	low	1	0
glycine	low	1	0
dihydroxyphenylalanine	medium	3	1
inositol	low	1	0
nitrous oxide	low	2	0
phosphorylethanolamine	low	1	0
quinolinic acid	low	1	0
taurine	low	1	0
thiamine	low	3	0
uric acid	low	1	0
2-amino-5-phosphonovalerate	low	1	0
alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid	low	2	0
3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid	low	1	0
ibotenic acid	low	2	0
sk&f 77434	low	1	0
sk&f-38393	low	1	0
homovanillic acid	medium	5	1
phenytoin	low	1	0
hydroxyindoleacetic acid	low	3	0
7-nitroindazole	low	1	0
amantadine	medium	3	3
biperiden	low	1	0
buspirone	medium	1	1
clonazepam	low	2	0
diazepam	low	1	0
flumazenil	low	3	0
flunitrazepam	medium	1	1
fluoxetine	low	1	0
iofetamine	low	1	0
isoflurane	low	1	0
apnea	low	1	0
pindolol	low	1	0
propofol	low	1	0
risperidone	low	1	0
trazodone	low	1	0
trihexyphenidyl	low	3	0
vesamicol	low	1	0
vigabatrin	medium	1	1
serine	low	2	0
aspartic acid	medium	2	1
glutamine	low	1	0
physostigmine	medium	1	1
apomorphine	low	1	0
tetrabenazine	low	1	0
adenosine diphosphate	low	1	0
levodopa	low	16	0
tryptophan	low	1	0
quinoxalines	low	2	0
indazoles	low	1	0
3-acetylpyridine	low	2	0
methoxyhydroxyphenylglycol	low	1	0
d-alpha tocopherol	low	1	0
n-methylaspartate	low	1	0
silver	low	2	0
xenon	medium	2	1
lisuride	low	1	0
transferrin	low	5	0
glutamic acid	low	7	0
substance p	low	2	0
vecuronium bromide	low	1	0
quisqualic acid	low	2	0
fomesafen	medium	5	2
fluorodopa f 18	low	1	0
3-iodobenzylguanidine	low	1	0
n-acetylaspartic acid	medium	1	1
fluorodeoxyglucose f18	medium	9	1
droxidopa	low	1	0
3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide	low	1	0
deoxyglucose	medium	6	1
dihydrotetrabenazine	low	1	0
glycerophosphoethanolamine	low	1	0
cyanopindolol	low	1	0
biotin	low	1	0
inositol 1,4,5-trisphosphate	low	3	0
nitroarginine	low	1	0
diprenorphine	low	1	0
cocaine	low	1	0
arginine vasopressin	low	1	0
6-cyano-7-nitroquinoxaline-2,3-dione	low	1	0
17-ketosteroids	low	1	0
4-hydroxy-2-nonenal	low	1	0
dextromethorphan	low	1	0
cysteine	low	1	0
dizocilpine maleate	low	2	0
i(3)so3-galactosylceramide	low	1	0
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	1	0
alpha-synuclein	low	8	0
oxadiazoles	low	1	0
brimonidine tartrate	low	1	0
technetium tc 99m exametazime	low	3	0
atrial natriuretic factor	low	1	0
neuropeptide y	low	1	0
phosphatidylcholines	low	1	0
cerebellin	low	1	0
glycolipids	low	1	0
piperidines	low	1	0
guanosine triphosphate	low	2	0
inosine triphosphate	low	1	0
clozapine	low	1	0
carbidopa	low	4	0
technetium tc 99m bicisate	low	1	0

Protein Targets (888)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	13	0	0	13
euchromatic histone-lysine N-methyltransferase 2	36	0	0	36
Bloom syndrome protein isoform 1	21	0	0	21
peripheral myelin protein 22 isoform 1	9	0	0	9
D(1A) dopamine receptor	12	0	0	12
lamin isoform A-delta10	23	0	0	23
Glutamate receptor 1	1	10	2	13
Glutamate receptor ionotropic, NMDA 1	0	19	3	25
Glutamate receptor ionotropic, kainate 3	0	9	0	9
Glutamate receptor ionotropic, NMDA 2A	0	19	3	25
Glutamate receptor ionotropic, NMDA 2B	0	19	3	25
Glutamate receptor ionotropic, NMDA 2C	0	19	3	25
Glutamate receptor ionotropic, NMDA 2D	0	19	3	25
Glutamate receptor ionotropic, NMDA 3B	0	19	3	25
Glutamate receptor ionotropic, NMDA 3A	0	19	3	25
ATP-dependent phosphofructokinase	19	0	0	19
Sodium-dependent dopamine transporter	0	6	1	7
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
regulator of G-protein signaling 4	19	0	0	19
nonstructural protein 1	4	0	0	4
thyroid hormone receptor beta isoform a	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
M-phase phosphoprotein 8	10	0	0	10
histone acetyltransferase KAT2A isoform 1	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
aryl hydrocarbon receptor	6	0	0	6
Nicotinamidase	0	1	0	1
D(2) dopamine receptor	0	13	3	21
D(4) dopamine receptor	0	6	2	11
D(3) dopamine receptor	0	13	1	17
D(2) dopamine receptor	0	15	6	21
dopamine D1 receptor	5	0	0	5
thioredoxin reductase	30	0	0	30
GLS protein	19	0	0	19
Thrombopoietin	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	7	0	0	7
cytochrome P450 2D6 isoform 1	8	0	0	8
cytochrome P450 2C19 precursor	9	0	0	9
ras-related protein Rab-9A	2	0	0	2
lethal factor (plasmid)	7	0	0	7
POU domain, class 2, transcription factor 1	0	0	0	1
Spike glycoprotein	7	0	0	7
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, Penicillin Amidohydrolase	0	1	0	1
Chain B, Penicillin Amidohydrolase	0	1	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	8	0	0	8
Chain A, HADH2 protein	8	0	0	8
Chain B, HADH2 protein	8	0	0	8
Chain A, JmjC domain-containing histone demethylation protein 3A	9	0	0	9
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
Chain A, Protocatechuate 3,4-dioxygenase	0	0	1	1
Chain M, Protocatechuate 3,4-dioxygenase	0	0	1	1
Olfactory receptor class A-like protein 1	0	0	1	1
Luciferase	7	0	0	7
endonuclease IV	9	0	0	9
RGS12	1	0	0	1
phosphopantetheinyl transferase	14	0	0	14
NFKB1 protein, partial	7	0	0	7
TDP1 protein	20	0	0	20
Microtubule-associated protein tau	12	0	0	12
alkaline phosphatase, intestinal	0	0	1	1
thioredoxin glutathione reductase	3	0	0	3
apical membrane antigen 1, AMA1	3	0	0	3
thyroid stimulating hormone receptor	14	0	0	14
hypothetical protein, conserved	3	0	0	3
lysosomal alpha-glucosidase preproprotein	2	0	0	2
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
intestinal alkaline phosphatase precursor	0	1	0	1
chromobox protein homolog 1	16	0	0	16
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
DNA polymerase beta	3	0	0	3
flap endonuclease 1	12	0	0	12
DNA polymerase iota isoform a (long)	10	0	0	10
geminin	16	0	0	16
alkaline phosphatase, germ cell type preproprotein	0	0	1	1
POsterior Segregation	0	0	1	1
muscarinic acetylcholine receptor M1	18	0	0	18
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	8	2	10
Zinc finger protein mex-5	0	0	1	1
vitamin D3 receptor isoform VDRA	7	0	0	7
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
15-lipoxygenase, partial	6	0	0	6
USP1 protein, partial	8	0	0	8
glucocerebrosidase	3	0	0	3
Glutamate receptor 1	0	5	2	7
Glutamate receptor 2	0	5	2	7
Glutamate receptor 3	0	4	1	5
Glutamate receptor 4	0	5	1	6
Inositol monophosphatase 1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
nuclear receptor ROR-gamma isoform 1	5	0	0	5
survival motor neuron protein isoform d	7	0	0	7
muscleblind-like protein 1 isoform 1	2	0	0	2
neuropeptide S receptor isoform A	5	0	0	5
Aromatase	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Nitric oxide synthase, endothelial	0	3	0	3
Nitric oxide synthase, endothelial	0	3	0	4
Nitric oxide synthase, brain	0	4	0	5
Nitric oxide synthase, brain	0	3	0	3
Nitric oxide synthase, inducible	0	3	0	3
Nitric oxide synthase, inducible	0	3	0	4
Nitric oxide synthase, endothelial	0	1	0	1
Chain A, Heat Shock Protein 90	0	0	1	1
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE	0	0	1	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN	0	1	0	1
Chain A, Myosin Ie Heavy Chain	0	0	1	1
Chain A, Preprotein translocase secA	0	0	1	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Ribonuclease pancreatic	0	1	0	1
Chain A, Phosphoribosylformylglycinamidine synthase	0	1	0	1
Chain A, nucleoside diphosphate kinase A	0	0	1	1
Chain B, nucleoside diphosphate kinase A	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain D, DNA polymerase III subunit gamma	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3	0	0	1	1
Chain A, Kinesin-like protein KIF11	0	1	0	1
HPr kinase/phosphorylase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
ATP-dependent molecular chaperone HSP82	0	0	0	1
Heat shock protein HSP 90-alpha	0	1	2	4
Heat shock protein HSP 90-beta	0	1	1	3
2-dehydropantoate 2-reductase	0	1	2	3
Heat shock 70 kDa protein 1A	0	1	1	2
Endoplasmic reticulum chaperone BiP	0	0	1	1
Heat shock cognate 71 kDa protein	0	0	1	1
Pyruvate kinase PKM	0	0	0	1
Pyruvate kinase PKLR	0	0	0	1
Endoplasmin	0	0	0	1
Heat shock cognate 71 kDa protein	0	0	1	1
5'-nucleotidase	0	1	0	1
Mu-type opioid receptor	0	1	1	2
Delta-type opioid receptor	0	1	1	2
Kappa-type opioid receptor	0	1	2	3
Endoplasmin	0	1	1	2
P2Y purinoceptor 2	0	0	1	1
Phosphatidylinositol 4-kinase alpha	0	2	0	2
P2X purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2Y purinoceptor 1	0	0	1	1
P2X purinoceptor 1	0	0	1	1
P2X purinoceptor 4	0	0	1	1
P2X purinoceptor 5	0	0	1	1
P2X purinoceptor 6	0	0	1	1
P2X purinoceptor 3	0	0	1	1
Heat shock protein 75 kDa, mitochondrial	0	1	0	1
P2Y purinoceptor 6	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
P2Y purinoceptor 11	0	0	1	1
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
P2Y purinoceptor 12	0	0	1	1
Sensor protein kinase WalK	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	2	0	2
P2X purinoceptor 2	0	0	1	1
arylsulfatase A	20	0	0	20
Glutamate receptor ionotropic, NMDA 2D	0	4	0	4
Glutamate receptor ionotropic, NMDA 3B	0	4	0	4
Integrin beta-3	2	1	1	4
Integrin alpha-IIb	2	1	1	4
Glutamate receptor 2	8	8	2	18
Glutamate receptor 3	1	8	2	11
Glutamate receptor 4	1	8	2	11
Glutamate receptor ionotropic, kainate 1	0	8	1	9
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	0	2
Glutamate receptor ionotropic, kainate 1	0	3	1	4
Glutamate receptor ionotropic, kainate 2	0	8	1	9
Excitatory amino acid transporter 1	0	4	0	5
Excitatory amino acid transporter 2	0	4	0	5
Excitatory amino acid transporter 3	0	4	0	5
Glutamate receptor ionotropic, kainate 4	0	6	0	6
Glutamate receptor ionotropic, NMDA 1	0	4	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	0	4
Glutamate receptor ionotropic, kainate 2	0	3	1	4
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Glutamate receptor ionotropic, NMDA 2B	0	4	0	4
Glutamate receptor ionotropic, NMDA 2C	0	4	0	4
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	6	0	6
Glutamate receptor ionotropic, NMDA 3A	0	4	0	4
Glutamate receptor 4	0	2	0	2
Glutamate receptor 3	0	2	0	2
acetylcholinesterase	9	0	0	9
RAR-related orphan receptor gamma	11	0	0	11
GLI family zinc finger 3	13	0	0	13
AR protein	16	0	0	16
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
EWS/FLI fusion protein	7	0	0	7
estrogen nuclear receptor alpha	19	0	0	19
putative alpha-glucosidase	1	0	0	1
thyroid hormone receptor beta isoform 2	8	0	0	8
heat shock protein beta-1	3	0	0	3
peripheral myelin protein 22	10	0	0	10
Solute carrier family 22 member 2	0	4	0	6
Solute carrier family 22 member 1	0	3	0	7
Matrix protein 2	0	1	1	2
Matrix protein 2	0	1	2	3
Solute carrier family 22 member 1	0	3	0	4
Multidrug and toxin extrusion protein 1	0	4	0	4
Solute carrier family 22 member 2	0	3	0	4
ATAD5 protein, partial	5	0	0	5
estrogen-related nuclear receptor alpha	15	0	0	15
Chain A, Putative fructose-1,6-bisphosphate aldolase	5	0	0	5
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	15	0	0	15
estrogen receptor 2 (ER beta)	5	0	0	5
nuclear receptor subfamily 1, group I, member 3	9	0	0	9
progesterone receptor	8	0	0	8
cytochrome P450 family 3 subfamily A polypeptide 4	11	0	0	11
farnesoid X nuclear receptor	3	0	0	3
cytochrome P450 2D6	9	0	0	9
peroxisome proliferator-activated receptor delta	4	0	0	4
peroxisome proliferator activated receptor gamma	6	0	0	6
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	5	0	0	5
thyroid stimulating hormone receptor	5	0	0	5
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	5	0	0	5
Histone H2A.x	6	0	0	6
cellular tumor antigen p53 isoform a	3	0	0	3
cytochrome P450 2C9 precursor	5	0	0	5
potassium voltage-gated channel subfamily H member 2 isoform d	6	0	0	6
mitogen-activated protein kinase 1	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	10	0	0	10
cytochrome P450 3A4 isoform 1	7	0	0	7
Gamma-aminobutyric acid receptor subunit pi	7	11	2	20
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
ATP-binding cassette sub-family C member 3	0	12	0	12
Multidrug resistance-associated protein 4	0	12	0	12
Voltage-dependent calcium channel gamma-2 subunit	7	0	0	7
Bile salt export pump	0	15	0	15
Cellular tumor antigen p53	8	0	0	8
5-hydroxytryptamine receptor 1A	0	9	8	17
5-hydroxytryptamine receptor 2C	0	12	0	12
Tryptophan 5-hydroxylase 1	0	2	0	2
5-hydroxytryptamine receptor 2A	0	13	0	13
Gamma-aminobutyric acid receptor subunit beta-1	7	11	2	20
Alpha-1B adrenergic receptor	0	10	2	12
Gamma-aminobutyric acid receptor subunit delta	7	11	2	20
Gamma-aminobutyric acid receptor subunit gamma-2	7	11	3	21
D	0	10	0	10
D(3) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 1A	0	18	1	19
Alpha-2B adrenergic receptor	0	7	2	9
Gamma-aminobutyric acid receptor subunit alpha-5	7	11	2	20
Gamma-aminobutyric acid receptor subunit alpha-3	7	11	2	20
D(2) dopamine receptor	0	5	0	5
D(1A) dopamine receptor	0	9	4	16
D(1B) dopamine receptor	0	4	0	6
Alpha-2C adrenergic receptor	0	7	2	9
Alpha-2A adrenergic receptor	0	7	2	9
Gamma-aminobutyric acid receptor subunit gamma-1	7	11	2	20
Gamma-aminobutyric acid receptor subunit alpha-2	7	11	2	20
Alpha-1D adrenergic receptor	0	10	2	12
D(1B) dopamine receptor	0	4	0	4
5-hydroxytryptamine receptor 2A	0	14	1	17
Gamma-aminobutyric acid receptor subunit alpha-4	7	11	2	20
Gamma-aminobutyric acid receptor subunit gamma-3	7	11	2	20
5-hydroxytryptamine receptor 1B	0	14	0	14
5-hydroxytryptamine receptor 1D	0	6	0	6
Gamma-aminobutyric acid receptor subunit alpha-6	7	11	2	20
D(4) dopamine receptor	0	4	1	5
5-hydroxytryptamine receptor 1F	0	6	0	6
5-hydroxytryptamine receptor 2B	0	12	1	13
5-hydroxytryptamine receptor 6	0	2	0	2
5-hydroxytryptamine receptor 7	0	5	0	5
5-hydroxytryptamine receptor 5A	0	2	0	2
5-hydroxytryptamine receptor 5B	0	2	0	2
5-hydroxytryptamine receptor 3A	0	3	0	3
Alpha-1A adrenergic receptor	0	10	2	12
Histamine H2 receptor	5	0	0	5
5-hydroxytryptamine receptor 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	7	11	3	21
Gamma-aminobutyric acid receptor subunit beta-3	7	11	2	20
Gamma-aminobutyric acid receptor subunit beta-2	7	11	3	21
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
D	0	2	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
GABA theta subunit	7	11	2	20
Canalicular multispecific organic anion transporter 1	0	10	0	10
D	0	5	0	5
ATPase family AAA domain-containing protein 5	3	0	0	3
Ataxin-2	8	0	0	8
Sigma non-opioid intracellular receptor 1	0	13	0	13
Gamma-aminobutyric acid receptor subunit epsilon	7	11	2	20
5-hydroxytryptamine receptor 3B	0	3	0	3
Translocator protein	0	1	2	4
Vasopressin V2 receptor	0	2	1	4
Oxytocin receptor	0	1	1	2
Vasopressin V1a receptor	0	0	2	2
Vasopressin V1a receptor	0	1	1	2
Vasopressin V1b receptor	0	1	1	2
Vasopressin V2 receptor	0	0	1	1
Vasopressin V1b receptor	0	1	1	3
Translocator protein	0	1	0	2
Oxytocin receptor	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Chain A, Ferritin light chain	3	0	0	3
Metabotropic glutamate receptor 6	0	2	2	5
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	2	0	7
Carbonic anhydrase 2	0	2	0	7
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Metabotropic glutamate receptor 1	0	3	3	7
Metabotropic glutamate receptor 2	0	3	4	8
Carbonic anhydrase-like protein, putative	0	0	0	5
Carbonic anhydrase 4	0	0	0	1
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Protein (streptavidin)	0	0	1	1
Chain B, Protein (streptavidin)	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain D, Streptavidin	0	0	1	1
Chain A, Streptavidin Complex With Biotin	0	0	1	1
Chain D, Circularly Permuted Core-streptavidin E51/a46	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Core-streptavidin	0	0	1	1
Chain D, Core-streptavidin	0	0	1	1
Chain A, Avidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
Chain A, Streptavidin	0	0	1	1
Chain B, Streptavidin	0	0	1	1
nonstructural protein 1	0	1	0	1
green fluorescent protein, partial	0	1	0	1
insulin-degrading enzyme isoform 1	0	0	1	1
Streptavidin	0	0	1	1
Receptor-type tyrosine-protein phosphatase beta	0	0	0	1
PPM1D protein	1	0	0	1
Interferon beta	7	0	0	7
Muscarinic acetylcholine receptor M2	0	6	1	7
Muscarinic acetylcholine receptor M4	0	6	1	7
Muscarinic acetylcholine receptor M1	0	8	1	9
Muscarinic acetylcholine receptor M3	0	9	1	10
retinoid X nuclear receptor alpha	2	0	0	2
pregnane X nuclear receptor	8	0	0	8
vitamin D (1,25- dihydroxyvitamin D3) receptor	7	0	0	7
Bile salt export pump	0	4	0	4
Beta-2 adrenergic receptor	0	3	0	4
Angiotensin-converting enzyme	0	1	0	1
Beta-1 adrenergic receptor	0	4	0	5
Alpha-1D adrenergic receptor	0	10	0	11
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 2C	0	14	2	16
5-hydroxytryptamine receptor 7	0	3	0	3
5-hydroxytryptamine receptor 2B	0	12	1	13
5-hydroxytryptamine receptor 3A	0	2	0	2
5-hydroxytryptamine receptor 6	0	8	0	9
Potassium voltage-gated channel subfamily H member 2	0	9	0	9
Alpha-2A adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Lysosomal alpha-glucosidase	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	4	0	4
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	4	0	4
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	3	0	4
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	3	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	10	0	10
Gamma-aminobutyric acid receptor subunit delta	0	10	0	10
Gamma-aminobutyric acid receptor subunit alpha-1	0	5	0	6
Gamma-aminobutyric acid receptor subunit beta-1	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-2	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-3	0	5	0	6
Gamma-aminobutyric acid receptor subunit alpha-1	0	12	7	19
Gamma-aminobutyric acid receptor subunit beta-1	0	10	2	12
Gamma-aminobutyric acid receptor subunit gamma-2	0	12	5	17
Gamma-aminobutyric acid receptor subunit alpha-4	0	5	0	6
Gamma-aminobutyric acid receptor subunit gamma-2	0	5	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	12	4	16
Translocator protein	0	2	0	2
Translocator protein	0	3	0	3
Cholecystokinin receptor type A	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	11	6	17
Gamma-aminobutyric acid receptor subunit alpha-3	0	11	4	15
Gamma-aminobutyric acid receptor subunit alpha-2	0	11	3	14
Gamma-aminobutyric acid receptor subunit beta-2	0	11	4	15
Gamma-aminobutyric acid receptor subunit alpha-4	0	10	2	12
Gamma-aminobutyric acid receptor subunit epsilon	0	10	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	0	11	2	13
Gamma-aminobutyric acid receptor subunit gamma-1	0	10	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	0	10	0	10
Gamma-aminobutyric acid receptor subunit theta	0	10	0	10
5-hydroxytryptamine receptor 3E	0	1	0	1
Fumarate hydratase	3	0	0	3
caspase 7, apoptosis-related cysteine protease	3	0	0	3
glucocorticoid receptor [Homo sapiens]	7	0	0	7
G	6	0	0	6
polyprotein	3	0	0	3
Beta-1 adrenergic receptor	0	1	0	1
bromodomain adjacent to zinc finger domain 2B	5	0	0	5
caspase-3	3	0	0	3
IDH1	5	0	0	5
Adenylate cyclase type 1	0	1	0	1
atrial natriuretic peptide receptor 2 precursor	3	0	0	3
short transient receptor potential channel 6 isoform 1	0	0	1	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 4	0	12	0	12
5-hydroxytryptamine receptor 3B	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	6	0	0	6
Albumin	0	0	5	5
Aldo-keto reductase family 1 member B1	0	6	0	6
ATP-dependent translocase ABCB1	0	1	0	4
Muscarinic acetylcholine receptor M1	0	3	0	3
Muscarinic acetylcholine receptor M3	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Cytochrome P450 3A4	0	3	0	4
Muscarinic acetylcholine receptor M5	0	2	0	2
Muscarinic acetylcholine receptor M5	0	7	0	7
Alpha-2A adrenergic receptor	0	9	0	10
Calmodulin-1	0	1	0	1
Cytochrome P450 2D6	0	6	0	8
Muscarinic acetylcholine receptor M2	0	4	0	4
Cytochrome P450 2C9	0	4	0	5
Angiotensin-converting enzyme	0	6	0	6
Alpha-2B adrenergic receptor	0	10	0	11
Alpha-2C adrenergic receptor	0	9	1	11
Endothelin receptor type B	0	1	0	1
Adenylate cyclase type 3	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Sodium-dependent dopamine transporter	0	7	0	7
5-hydroxytryptamine receptor 3A	0	1	0	1
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	6	0	6
Adenosine receptor A1	0	1	0	2
Adenylate cyclase type 2	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
Histamine H1 receptor	0	2	0	2
Histamine H1 receptor	0	2	0	2
Sodium-dependent serotonin transporter	0	11	2	13
Sodium-dependent serotonin transporter	0	6	0	7
Cytochrome P450 2C19	0	1	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Alpha-1A adrenergic receptor	0	3	0	4
5-hydroxytryptamine receptor 2A	0	2	0	2
Histamine H1 receptor	0	8	2	12
Alpha-1B adrenergic receptor	0	2	0	3
Adenylate cyclase type 8	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
Cytochrome P450 2J2	0	3	0	4
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Calmodulin	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
5-hydroxytryptamine receptor 2B	0	2	0	2
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 5	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Transporter	0	3	0	3
Cholecystokinin receptor type A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Nuclear receptor subfamily 3 group C member 3	0	6	0	6
5-hydroxytryptamine receptor 3D	0	1	0	1
Adenylyl cyclase 7	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
Inositol hexakisphosphate kinase 1	6	0	0	6
Histamine H4 receptor	0	1	1	2
Sigma non-opioid intracellular receptor 1	0	4	0	4
Transporter	0	5	0	5
Histamine H3 receptor	0	3	0	3
cytochrome P450 2C9, partial	6	0	0	6
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	0	2	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Sodium-dependent dopamine transporter	0	3	0	3
Leukotriene B4 receptor 2	0	1	0	1
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	5	0	5
Beta-2 adrenergic receptor	0	4	2	6
Deoxycytidine kinase	0	0	0	1
activating transcription factor 6	3	0	0	3
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Taste receptor type 2 member 46	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	3	0	3
Cytochrome P450 2D4	0	1	0	1
Gamma-aminobutyric acid	0	2	1	3
glp-1 receptor, partial	3	0	0	3
Fatty acid-binding protein, liver	0	1	0	1
Alpha-1-acid glycoprotein 1	0	0	0	1
Albumin	0	0	1	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit delta	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	2	1	3
Gamma-aminobutyric acid receptor subunit pi	0	2	1	3
Sphingosine-1-phosphate lyase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	2	1	3
Gamma-aminobutyric acid receptor subunit theta	0	2	1	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	2	1	3
Synaptic vesicular amine transporter	0	3	1	4
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
runt-related transcription factor 1 isoform AML1b	2	0	0	2
core-binding factor subunit beta isoform 2	2	0	0	2
DNA polymerase kappa isoform 1	7	0	0	7
Epidermal growth factor receptor	0	2	0	2
Caspase-7	1	0	0	1
Delta-type opioid receptor	0	0	0	1
Kappa-type opioid receptor	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
TAR DNA-binding protein 43	4	0	0	4
Caspase-7	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
caspase-3	1	0	0	1
huntingtin isoform 2	1	0	0	1
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
Sodium-dependent noradrenaline transporter	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Acetylcholinesterase	0	2	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Potassium voltage-gated channel subfamily C member 1	0	1	0	1
D(1A) dopamine receptor	1	0	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Cytochrome P450 1B1	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	2	0	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit rho-3	0	0	1	1
Hsf1 protein	0	0	1	1
transcriptional regulator ERG isoform 3	4	0	0	4
histone-lysine N-methyltransferase 2A isoform 2 precursor	3	0	0	3
Histone deacetylase 3	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 2	0	1	1	2
Gamma-aminobutyric acid type B receptor subunit 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit rho-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit rho-2	0	0	1	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent taurine transporter	0	2	0	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Histone deacetylase 4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	2
Histone deacetylase 1	0	1	0	1
Sterol O-acyltransferase 1	0	0	1	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 2	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 11	0	1	0	1
Histone deacetylase 8	0	1	0	1
Platelet glycoprotein VI	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Histone deacetylase 6	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	1	2
Histone deacetylase 9	0	1	0	1
Histone deacetylase 5	0	1	0	1
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	1	1
ATP-citrate synthase	0	1	0	1
Metabotropic glutamate receptor 1	0	2	3	5
Metabotropic glutamate receptor 2	0	0	2	2
Metabotropic glutamate receptor 3	0	0	2	2
Metabotropic glutamate receptor 4	0	1	2	3
Metabotropic glutamate receptor 5	0	0	2	2
Metabotropic glutamate receptor 6	0	0	2	2
Metabotropic glutamate receptor 7	0	0	2	2
Metabotropic glutamate receptor 5	0	3	2	6
Metabotropic glutamate receptor 8	0	0	2	2
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Glutamate carboxypeptidase 2	0	2	0	2
Metabotropic glutamate receptor 7	0	1	2	4
Metabotropic glutamate receptor 3	0	2	1	4
Metabotropic glutamate receptor 4	0	3	3	7
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Chain A, Glutamine Binding Protein	0	0	1	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Amino acid transporter	0	2	0	2
Glycine receptor subunit alpha-1	0	0	2	2
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	3	0	3
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	0	1	1
Chain B, Uracil Phosphoribosyltransferase	0	0	1	1
Chain C, Uracil Phosphoribosyltransferase	0	0	1	1
67.9K protein	3	0	0	3
Ras-related protein Rab-7a	0	0	1	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9	0	2	0	2
ClpP	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Smad3	3	0	0	3
alpha-galactosidase	2	0	0	2
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Chain A, Beta-lactamase	2	0	0	2
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, CELL DIVISION PROTEIN KINASE 2	0	1	0	1
Chain A, Cell Division Protein Kinase 2	0	1	0	1
DNA repair and recombination protein RadA	0	0	1	1
Cyclin-dependent kinase 1	0	1	0	1
G2/mitotic-specific cyclin-B1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	1	3
Cyclin-A2	0	1	0	1
Cyclin-dependent kinase 2	0	1	0	1
RAC-alpha serine/threonine-protein kinase	0	1	0	1
Cyclin-A1	0	1	0	1
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Sodium/myo-inositol cotransporter 2	0	1	0	1
Chain A, BETA-SPECTRIN	0	0	1	1
Chain A, Phospholipase C Delta-1	0	0	1	1
Chain A, Inositol 1,4,5-trisphosphate receptor type 1	0	0	1	1
Inositol-trisphosphate 3-kinase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	0	2	2
Inositol 1,4,5-trisphosphate receptor type 2	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 3	0	1	1	2
Inositol polyphosphate-5-phosphatase A	0	1	0	1
Inositol 1,4,5-trisphosphate receptor type 1	0	1	1	2
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
DNA polymerase eta isoform 1	1	0	0	1
Polyphenol oxidase 2	0	0	0	1
Carbonic anhydrase 12	0	0	0	2
Plasma kallikrein	0	0	0	2
Tyrosine-protein kinase Lck	0	1	0	1
Tyrosine-protein kinase Fyn	0	1	0	1
Carbonic anhydrase 3	0	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Tyrosinase	0	1	0	1
Carbonic anhydrase 4	0	0	0	2
Carbonic anhydrase 6	0	1	0	3
Adenosine receptor A2a	0	0	0	1
Carbonic anhydrase 5A, mitochondrial	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase 7	0	0	0	2
Solute carrier family 15 member 1	0	1	0	1
Carbonic anhydrase	0	0	0	2
SLC16A10 protein	0	0	0	2
Carbonic anhydrase 9	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Carbonic anhydrase 15	0	0	0	2
Carbonic anhydrase 13	0	0	0	2
Carbonic anhydrase 14	0	0	0	2
Carbonic anhydrase 5B, mitochondrial	0	0	0	2
phosphoglycerate kinase	1	0	0	1
Beta-1 adrenergic receptor	0	4	1	5
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Neuropeptide Y receptor type 1	0	2	0	2
Neuropeptide Y receptor type 2	0	2	0	2
prostaglandin E2 receptor EP2 subtype	0	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Acetylcholinesterase	0	3	0	4
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Cholinesterase	0	3	0	4
Cholinesterase	0	1	0	1
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Parkin	1	0	0	1
Beta-3 adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1B	0	1	0	1
Angiotensin-converting enzyme	0	1	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	1
Lysine-specific demethylase 4E	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Advanced glycosylation end product-specific receptor	0	0	1	1
Beta-lactamase	0	1	0	1
Advanced glycosylation end product-specific receptor	0	0	1	1
Chain A, Glutamate Receptor 2	0	1	0	1
Chain A, Glutamate Receptor 2	0	1	0	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
Cystine/glutamate transporter	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Replicase polyprotein 1ab	0	1	0	1
Substance-P receptor	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Substance-K receptor	0	1	1	2
Substance-K receptor	0	2	0	2
Substance-P receptor	0	2	1	3
Neuromedin-K receptor	0	1	1	2
Substance-P receptor	0	2	0	2
Substance-K receptor	0	1	0	1
Substance-K receptor	0	1	0	1
Growth hormone secretagogue receptor type 1	0	0	1	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Chain A, Cruzipain	1	0	0	1
pregnane X receptor	1	0	0	1
GALC protein	1	0	0	1
Synaptic vesicular amine transporter	0	2	1	3
Synaptic vesicular amine transporter	0	1	0	1
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Myeloperoxidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Stromelysin-1	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
Guanine deaminase	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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