Page last updated: 2024-09-27

Deficiency Syndrome, Leukocyte-Adhesion

Synonyms(1)

Synonym
Deficiency Syndrome, Leukocyte-Adhesion

Research

Studies (99)

TimeframeStudies, This Condition (%)All Conditions %
pre-19901 (1.01)23.3326
1990's35 (35.35)12.5806
2000's46 (46.46)18.1394
2010's12 (12.12)28.8240
2020's5 (5.05)9.53
DrugIndicatedRelationship StrengthStudiesTrials
phosphoserine0low10
adenine0low10
cytosine0low10
glycine0low10
thymine0low10
busulfan0low30
erythrosine0low10
gentamicin0low10
ethidium0low10
prednisolone0low10
aspartic acid0low10
cycloheximide0low10
egtazic acid0low10
threonine0low10
nitroblue tetrazolium0low10
citrulline0low10
fusarium0low10
luminol0low10
vancomycin0low10
fucose0low240
fluorescein-5-isothiocyanate0low10
manganese0low10
tetradecanoylphorbol acetate0low50
4-methoxyamphetamine0low10
transferrin0low10
phorbol 12,13-dibutyrate0low10
glucose, (beta-d)-isomer0low40
fibrinogen0low10
1-hexadecyl-2-acetyl-glycero-3-phosphocholine0low10
n-acetylglucopyranosylamine0low10
wortmannin0low10
glucosamine0low20
n-formylmethionine leucyl-phenylalanine0low50
mycophenolic acid0low10
alpha-chymotrypsin0low10
leukotriene b40low10
phenylephrine hydrochloride0low10
cysteine0low10
dolichols0low10
i(3)so3-galactosylceramide0low10
chlorhexidine0low10
amoxicillin-potassium clavulanate combination0low10
mocetinostat0low40
ribose0low10
alpha-Neup5Ac-(2->3)-beta-D-Galp-(1->4)-[alpha-L-Fucp-(1->3)]-D-GlcpNAc0low30
ly-1460320low10
interleukin-80low70
transforming growth factor beta0low10
lewis x antigen0low50
daptomycin0low10
cyclosporine0low20
lactoferrin0low10
guanosine diphosphate mannose0low30
guanine0low10
cytarabine0low120
concanavalin a0low20

Protein Targets (484)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain A, Cruzipain2002
regulator of G-protein signaling 42002
Platelet-activating factor receptor0202
Inositol monophosphatase 12002
5-hydroxytryptamine receptor 2C0112
5-hydroxytryptamine receptor 2A0112
5-hydroxytryptamine receptor 1A0112
5-hydroxytryptamine receptor 1B0112
5-hydroxytryptamine receptor 1D0112
5-hydroxytryptamine receptor 1F0112
5-hydroxytryptamine receptor 2B0112
5-hydroxytryptamine receptor 60011
Sodium-dependent serotonin transporter0011
Sodium-dependent serotonin transporter0303
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma9009
TDP1 protein120012
AR protein100010
nuclear receptor subfamily 1, group I, member 35005
cytochrome P450 family 3 subfamily A polypeptide 46006
glucocorticoid receptor [Homo sapiens]7007
estrogen-related nuclear receptor alpha130013
pregnane X nuclear receptor5005
estrogen nuclear receptor alpha130013
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
nuclear factor erythroid 2-related factor 2 isoform 26006
heat shock protein beta-13003
importin subunit beta-1 isoform 14004
snurportin-14004
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 13003
lamin isoform A-delta108008
Voltage-dependent calcium channel gamma-2 subunit6006
Bile salt export pump0808
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Glutamate receptor 26107
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 436006
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 55005
Ataxin-25005
peripheral myelin protein 226006
histone acetyltransferase KAT2A isoform 14004
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40707
Canalicular multispecific organic anion transporter 10707
Aminoglycoside 3'-phosphotransferase 0001
ATP-dependent phosphofructokinase2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
Chain A, Ferritin light chain1001
phosphopantetheinyl transferase4004
aldehyde dehydrogenase 1 family, member A19009
arylsulfatase A2002
euchromatic histone-lysine N-methyltransferase 2100010
Bloom syndrome protein isoform 15005
cytochrome P450 2C19 precursor2002
lethal factor (plasmid)6006
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10001
Carbonic anhydrase 20001
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0314
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0314
Glutamate receptor ionotropic, NMDA 2B0314
Glutamate receptor ionotropic, NMDA 2C0314
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, NMDA 2D0314
Glutamate receptor ionotropic, NMDA 3B0314
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0314
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, 2-oxoglutarate Oxygenase3003
15-lipoxygenase, partial2002
apical membrane antigen 1, AMA11001
thyroid stimulating hormone receptor3003
EWS/FLI fusion protein4004
retinoic acid nuclear receptor alpha variant 17007
retinoid X nuclear receptor alpha7007
aryl hydrocarbon receptor7007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
thyroid hormone receptor beta isoform 25005
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
nuclear factor erythroid 2-related factor 2 isoform 18008
geminin100010
Matrix metalloproteinase-90202
Disintegrin and metalloproteinase domain-containing protein 171001
Chain A, BCL-2-RELATED PROTEIN A10011
Luciferase2002
acid sphingomyelinase1001
interleukin 82002
acetylcholinesterase3003
PAX80001
glp-1 receptor, partial4004
pregnane X receptor2002
hypoxia-inducible factor 1 alpha subunit3003
SMAD family member 23003
USP1 protein, partial3003
SMAD family member 33003
GLI family zinc finger 36006
caspase 7, apoptosis-related cysteine protease1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
PINK11001
estrogen receptor 2 (ER beta)4004
progesterone receptor5005
farnesoid X nuclear receptor4004
G4004
cytochrome P450 2D63003
67.9K protein5005
glucocerebrosidase1001
Parkin1001
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma5005
vitamin D (1,25- dihydroxyvitamin D3) receptor5005
heat shock protein 900011
caspase-31001
IDH15005
calcineurin A1, putative0011
thyroid stimulating hormone receptor3003
activating transcription factor 66006
v-jun sarcoma virus 17 oncogene homolog (avian)4004
Histone H2A.x7007
cytochrome P450 2D6 isoform 11001
hepatocyte nuclear factor 4-alpha isoform 20101
cellular tumor antigen p53 isoform a2002
cytochrome P450 2C9 precursor1001
perilipin-50101
thyroid hormone receptor beta isoform a7007
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d1001
transcriptional regulator ERG isoform 32002
huntingtin isoform 21001
mitogen-activated protein kinase 12002
ubiquitin-conjugating enzyme E2 N0101
nuclear factor NF-kappa-B p105 subunit isoform 12002
flap endonuclease 12002
protein AF-9 isoform a0001
melanocortin receptor 40101
CAAX prenyl protease0001
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
bcl-2-related protein A10101
urokinase plasminogen activator surface receptor precursor3003
nuclear receptor ROR-gamma isoform 15005
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
DNA polymerase kappa isoform 14004
cytochrome P450 3A4 isoform 13003
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
Gamma-aminobutyric acid receptor subunit pi3003
Synaptojanin-20101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0102
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 4004
Cellular tumor antigen p538008
Integrin beta-31001
72 kDa type IV collagenase0101
Integrin alpha-IIb1001
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Trypanothione reductase0101
Gamma-aminobutyric acid receptor subunit alpha-63003
Alpha-synuclein4004
Histamine H2 receptor1001
Nuclear receptor ROR-gamma2002
Spike glycoprotein2013
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 41001
GABA theta subunit3003
Inositol hexakisphosphate kinase 14004
Multidrug and toxin extrusion protein 10101
Gamma-aminobutyric acid receptor subunit epsilon3003
Spermine oxidase0101
cytochrome P450 2C9, partial4004
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
General amino-acid permease GAP10001
Nitric oxide synthase, brain0101
Nitric oxide synthase, brain 0101
ATAD5 protein, partial3003
Fumarate hydratase2002
PPM1D protein2002
Smad33003
polyprotein2002
P531001
RPL19A0011
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor1001
chromobox protein homolog 13003
ras-related protein Rab-9A1001
heat shock protein HSP 90-alpha isoform 20002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
survival motor neuron protein isoform d2002
COUP transcription factor 2 isoform a0101
Transmembrane protease serine 20011
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0011
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Solute carrier family 2, facilitated glucose transporter member 10101
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0011
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0002
Deoxycytidine kinase0001
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
endonuclease IV1001
peripheral myelin protein 22 isoform 11001
D(1A) dopamine receptor1001
Chain A, Beta-lactamase2002
Chain A, ATP-DEPENDENT DNA HELICASE Q13003
Genome polyprotein 0112
chaperonin-containing TCP-1 beta subunit homolog1001
GLS protein2002
thioredoxin glutathione reductase2002
hypothetical protein, conserved1001
bromodomain adjacent to zinc finger domain 2B1001
thyrotropin-releasing hormone receptor2002
vitamin D3 receptor isoform VDRA5005
eyes absent homolog 2 isoform a1001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
Microtubule-associated protein tau3003
DNA polymerase iota isoform a (long)2002
Reverse transcriptase/RNaseH 0101
Fucose-binding lectin PA-IIL0101
CD209 antigen0202
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10101
Proton-coupled amino acid transporter 10101
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
Leukotriene B4 receptor 10202
Leukotriene B4 receptor 20101
thioredoxin reductase3003
tumor necrosis factor1001
NEDD8-activating enzyme E1 regulatory subunit isoform a0101
NEDD8-conjugating enzyme Ubc120101
Queuine tRNA-ribosyltransferase0101
60 kDa heat shock protein, mitochondrial0202
10 kDa heat shock protein, mitochondrial0202
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20012
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
streptokinase A precursor0011
Beta-lactamase0001
Beta-lactamase SHV-10001
Beta-lactamase0001
Beta-lactamase TEM0001
B2 metallo-beta-lactamase 0001
Metallo-beta-lactamase VIM-130001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0012
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Histamine H3 receptor0001
Beta-lactamase class B VIM-2 0012
Beta-lactamase 0001
Beta-lactamase VIM-1 0001
Thioredoxin reductase 0101
muscleblind-like protein 1 isoform 11001
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Lanosterol 14-alpha demethylase0101
Histone deacetylase 30202
Nuclear receptor corepressor 10101
Integrin beta-10101
Cytochrome P450 3A40101
Leukotriene A-4 hydrolase0101
Cytochrome P450 2D60101
Integrin alpha-40101
Cytochrome P450 2C190101
Histone deacetylase 40101
Potassium voltage-gated channel subfamily H member 20101
Histone deacetylase 10202
Histone deacetylase 70101
Histone deacetylase 20202
Histone deacetylase 11 0101
Histone deacetylase 80101
Histone deacetylase 60101
Histone deacetylase 50101
Nuclear receptor corepressor 20101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
UDP-glucuronosyltransferase 1A90001
Inosine-5'-monophosphate dehydrogenase 20202
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
UDP-glucuronosyltransferase 1A1 0001
Peroxisome proliferator-activated receptor gamma0011
Inosine-5'-monophosphate dehydrogenase0102
UDP-glucuronosyltransferase 1A70001
UDP-glucuronosyltransferase 1A100001
UDP-glucuronosyltransferase 1A80001
Formyl peptide receptor-related sequence 10011
fMet-Leu-Phe receptor0224
N-formyl peptide receptor 20022
FML2_HUMAN 0011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
GALC protein1001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr2002
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Protein kinase C alpha type0101
Protein kinase C gamma type0224
Protein kinase C beta type0224
Proto-oncogene vav0011
Protein kinase C alpha type0225
Protein kinase C eta type0123
Protein kinase C delta type0112
Protein kinase C epsilon type0224
Protein kinase C theta type0123
Protein kinase C delta type0224
Sigma non-opioid intracellular receptor 10011
Transient receptor potential cation channel subfamily V member 4 0011
luciferase0001
nuclear receptor subfamily 1, group I, member 21001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Cytochrome P450 2C9 0101
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Histamine H1 receptor0011
Prostaglandin G/H synthase 20101
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
Serine/threonine-protein kinase D30011
Luciferin 4-monooxygenase0011
Beta-1 adrenergic receptor0101
Protein kinase C iota type0011
Protein kinase C zeta type0011
Serine/threonine-protein kinase D10011
Ras guanyl-releasing protein 30011
Thymidine phosphorylase0101
Albumin0011
Alpha-2A adrenergic receptor0101
Alpha-1B adrenergic receptor0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Alpha-1A adrenergic receptor0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
Nrf21001
WRN1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
endoribonuclease toxin MazF0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0112
Serine/threonine-protein kinase PLK40101
Myosin light chain kinase, smooth muscle0101
Metabotropic glutamate receptor 10101
Phosphatidylinositol 3-kinase regulatory subunit alpha0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0213
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0112
Serine/threonine-protein kinase mTOR0112
Phosphatidylinositol 4-kinase alpha0101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0112
Serine/threonine-protein kinase PLK10202
Guanine nucleotide-binding protein G1001
DNA-dependent protein kinase catalytic subunit0101
Myosin light chain kinase, smooth muscle0101
Phosphoinositide 3-kinase regulatory subunit 50101
Phosphatidylinositol 4-kinase type 2-alpha0101
Serine/threonine-protein kinase PLK30202
Serine/threonine-protein kinase PLK20101
Phosphatidylinositol 4-kinase beta0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]