Page last updated: 2024-09-27

Deficiency Disease, Ornithine Carbamoyltransferase

Synonyms(7)

Synonym
Ornithine Transcarbamylase Deficiency Disease
Ornithine Transcarbamylase Deficiency
Deficiency Disease, Ornithine Transcarbamylase
OTC Deficiency
Deficiency Disease, Ornithine Carbamoyltransferase
Ornithine Carbamoyltransferase Deficiency
Ornithine Transcarbamylase Deficiency, Hyperammonemia Due To

Research Excerpts

Overview

ExcerptReference
"Ornithine transcarbamylase deficiency is an X-linked recessive disorder of urea biosynthesis characterized by recurrent, often fatal, hyperammonemic encephalopathy in affected males; carrier females are usually asymptomatic."( Blaser, S; Clarke, JT; Pridmore, CL, 1995)
"Ornithine transcarbamylase deficiency is an X-linked disorder of the urea cycle that can cause hyperammonemic encephalopathy in hemizygous males and heterozygous females."( Boyer, JL; Brusilow, SW; Felig, DM, 1995)
"OTC deficiency is the most common urea cycle defect and typically is diagnosed in male infants with irritability, poor feeding, vomiting, lethargy, and often death caused by the effects of hyperammonemia."( Myers, JH; Shook, JE, 1996)
"OTC deficiency is an X-linked genetic disorder, usually causing neonatal or infantile hyperammonemia, coma and death."( Hou, JW; Wang, TR, 1996)
"Ornithine transcarbamylase deficiency is an X linked disorder and the most common inherited cause of hyperammonaemia."( Kohlschütter, A; Oechsner, M; Steen, C; Stürenburg, HJ, 1998)
"OTC deficiency is an X-linked disorder that causes hyperammonemia leading to brain damage, mental retardation and death."( McCullough, BA; Tuchman, M; Yudkoff, M, 2000)
"Ornithine transcarbamylase deficiency is a very heterogeneous urea cycle disorder resulting in hyperammonemia with various presentations from the neonatal period through adulthood."( Burlina, AB; Korall, H; Ogier, H; Trefz, FK, 2001)
"X-linked inherited ornithine transcarbamylase deficiency is the most frequent urea cycle disorder."( Garrigue, MA; Kouatchet, A; Labarthe, F; Legras, A; Maillot, F; Ogier de Baulny, H, 2002)
"The prognosis of ornithine transcarbamylase deficiency is better for those with an onset after infancy, but morbidity from brain damage does not appear to be linked to the number of episodes of hyperammonaemia that have occurred."( Gordon, N, 2003)
"OTC deficiency is the most common urea cycle defect causing hyperammonemia."( Fraser, DD; Ramsay, DA; Rupar, CA; Singh, R; Thakur, V, 2006)
"Ornithine transcarbamylase deficiency is the most common inherited urea cycle disorder."( Duława, J; Hawrot-Kawecka, AM; Kawecki, GP, 2006)
"Ornithine transcarbamylase deficiency is the commonest urea cycle disorder which is transmitted in X-linked inheritance."( Chan, GC; Kwong, NS; Lam, CW; Lau, KY; Li, SK; Low, LC; Mak, CM; Poon, GW; Siu, TS; Tam, S; Tang, NL; Wong, KY, 2007)
"OTC deficiency is an X-linked genetic disorder ranging from fatal in newborns to hyperammonemia and anorexia in adults."( Guan, KL; Huang, W; Lei, Q; Lin, Y; Xiong, Y; Yao, J; Yu, W; Zhao, S, 2009)
"Gene therapy for OTC deficiency is effective in animals, and work is ongoing to improve persistence and safety."( Walker, V, 2009)
"Ornithine transcarbamylase deficiency is a rare X-linked disorder in which female carriers are usually heterozygous for the ornithine transcarbamylase deficiency gene."( Allen, TK; Constantinescu, OC; Habib, AS; Ituk, U; Small, MJ, 2012)
"Ornithine carbamoyltransferase deficiency is the most common inherited defect of the urea cycle."( Chuzhanova, N; Dvorakova, L; Hrebicek, M; Jirsa, M; Luksan, O; Majer, F; Peskova, K; Storkanova, G; Stranecky, V; Vlaskova, H; Zeman, J, 2013)
"Ornithine transcarbamylase deficiency is the most common of the urea cycle disorders."( Lachmann, R; Mehta, S; Tayabali, S, 2018)
"Ornithine transcarbamylase deficiency is an X-linked disorder which results in the accumulation of ammonia causing irritability and vomiting."( Fuchigami, T; Iwata, Y; Katagiri, J; Yoshida, H, 2023)

Context

ExcerptReference
"Most patients with ornithine transcarbamylase deficiency have markedly reduced or undetectable enzyme protein in their liver, therefore."( Butkowski, RJ; Holzknecht, RA; Tuchman, M; Zhang, W, 1990)
"Late-onset OTC deficiency has been described in patients of all ages."( Myers, JH; Shook, JE, 1996)
"Although OTC deficiency has been described as the most common inborn error of ureagenesis in humans, to our knowledge, this is the first report in a Chinese family confirmed by biochemical and DNA analyses."( Hou, JW; Wang, TR, 1996)
"One patient with OTC deficiency has had a liver transplant."( Keskinen, P; Salo, M; Siitonen, A, 2008)

Treatment

ExcerptReference
"A male infant with ornithine transcarbamylase deficiency developed massive neonatal hyperammonemia and was treated with peritoneal dialysis."( Kulovich, S; Nyhan, WL; Shumacher, AE; Wolff, J, 1985)
"B6 status in a patient with OTC deficiency during the therapy with benzoate."( Fujiwara, K; Kamoshita, S; Kodama, H; Motokawa, Y; Nose, O; Tajiri, H, 1983)
"We describe here two patients with OTC deficiency, one a late on-set female patient (case 1) and the other a neonatal-onset male patient (case 2), who were successfully treated with orthotopic liver transplantation (OLTx)."( Finegold, DN; Hasegawa, T; Nour, B; Reyes, J; Starzl, TE; Todo, S; Tzakis, AG, 1995)
"Girls with symptomatic ornithine transcarbamylase deficiency who are treated with drugs that activate new pathways of waste-nitrogen excretion have fewer hyperammonemic episodes and a reduced risk of further cognitive decline."( Bassett, SS; Brusilow, SW; Clissold, DB; Maestri, NE, 1996)
"We present a rare case of a late-onset OTC deficiency in a juvenile male patient receiving valproic acid therapy who developed fatal cerebral edema."( Fraser, DD; Ramsay, DA; Rupar, CA; Singh, R; Thakur, V, 2006)
"Gene therapy for OTC deficiency is effective in animals, and work is ongoing to improve persistence and safety."( Walker, V, 2009)

Research

Studies (550)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990176 (32.00)23.3326
1990's167 (30.36)12.5806
2000's117 (21.27)18.1394
2010's63 (11.45)28.8240
2020's27 (4.91)9.53
DrugIndicatedRelationship StrengthStudiesTrials
acetylcarnitine0low40
n-carbamoyl-beta-alanine0low20
adenine0low10
adipic acid0low10
ammonium hydroxide0medium2953
beta-alanine0low20
benzoic acid0medium161
carbamates0low30
carbamyl phosphate0low90
ureidosuccinic acid0low10
carnitine0low50
choline0low10
citric acid, anhydrous0low20
methylmalonic acid0low90
phosphonoacetic acid0low10
creatine0medium31
cytosine0low10
lactic acid0low20
glutaric acid0low20
glycine0low110
glycerol0low10
glycocyamine0low10
dalteparin0low10
hydrogen0low10
inositol0low20
orotic acid0medium995
phenylacetic acid0medium102
propionic acid0low30
pteridines0low10
pyridoxine0low10
pyruvic acid0low30
quinolinic acid0low10
succinic acid0low20
thymine0low20
uracil0low140
urea0medium1473
pk 111950low10
1-anilino-8-naphthalenesulfonate0low10
homovanillic acid0low10
phenytoin0low20
hydroxyindoleacetic acid0low20
aspirin0low30
chlorpromazine0low10
cyproheptadine0low10
valproic acid0low150
fentanyl0low40
flumazenil0low10
fluorouracil0low10
isoflurane0low20
ketamine0low20
lorazepam0low10
midazolam0low30
deet0low10
phenobarbital0low10
4-phenylbutyric acid0low30
phenylbutazone0low30
sevoflurane0low10
prednisolone0low10
alanine0low120
serine0low10
aspartic acid0low60
glutamine0medium442
lysine0low70
uridine0medium131
carbostyril0low10
tyrosine0low30
leucine0low30
methionine0low10
phenylalanine0low10
cycloheximide0low10
mannitol0low10
cytarabine0low20
ornithine0low310
asparagine0low10
histidine0low30
valine0low10
tryptophan0low40
isoleucine0low10
arginine0medium583
phosphoribosyl pyrophosphate0low10
pyrrolidonecarboxylic acid0low10
mephobarbital0low10
isoxazoles0low10
pyrimidine0low20
citrulline0medium561
4-fluorobenzoic acid0low10
monomethyl succinate0low10
isovaleric acid0low20
myristic acid0low10
diepoxybutane0low10
ethylmalonic acid0low10
deoxycytidine0low20
pseudouridine0low30
tetrabutylammonium0low10
methionine sulfoximine0low10
molybdenum0low10
deuterium0low10
ammonium chloride0low60
dimethyl alpha-ketoglutarate0low10
phytanic acid0low10
daunorubicin0low20
glutamic acid0low30
s-adenosylmethionine0low10
gemcitabine0low10
homocitrulline0low50
norvaline0low10
n-acetylglutamic acid0low30
coenzyme a0low30
phenylacetylglutamine0low20
orotidine0medium111
5-fluoromethylornithine0low10
carglumic acid0low20
n(delta)-(phosphonoacetyl)-l-ornithine0low10
proline0low20
acivicin0low10
mevalonic acid0low10
acetyl coenzyme a0low20
tretinoin0low20
arachidonic acid0low10
palmitoleic acid0low10
tacrolimus0low20
sodium acetate, anhydrous0low20
sodium benzoate0medium161
isomethyleugenol0low10
n-glycylalanine0low10
zinc oxide0low10
bilirubin0low30
linoleic acid0low10
alpha-linolenic acid0low10
l 6835900low10
dizocilpine maleate0low20
glycerol phenylbutyrate0low10
lactulose0low30
nad0low10
bivalirudin0low10
endothelin-10low10
quetiapine fumarate0low10
peptones0low10
hirudin0low10
glutaminase0low20
vitamin b 120low10
exudates0low10
guanine0low10
folic acid0low10
allopurinol0medium233
cytidylyl-3'-5'-guanosine0low10
molybdenum cofactor0low10

Protein Targets (1,037)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain B, pheromone binding protein0011
Chain A, pheromone binding protein0011
Chain A, JmjC domain-containing histone demethylation protein 3A5005
Chain A, RNA-directed RNA polymerase NS50101
acid sphingomyelinase3003
thioredoxin reductase160016
USP1 protein, partial160016
TDP1 protein280028
vitamin D3 receptor isoform VDRA9009
importin subunit beta-1 isoform 15005
flap endonuclease 1100010
serine/threonine-protein kinase PLK13003
snurportin-15005
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
GTP-binding nuclear protein Ran isoform 14004
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)140014
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
geminin290029
DNA polymerase kappa isoform 1120012
fibroblast growth factor 22 isoform 1 precursor0001
Mitogen-activated protein kinase 130101
Beta-lactamase0101
Transthyretin0112
Fatty acid-binding protein, intestinal0112
Fatty acid-binding protein, adipocyte0426
Cyclin-A20101
Cannabinoid receptor 10011
Cyclin-dependent kinase 20112
Choline O-acetyltransferase0202
Mitogen-activated protein kinase 120101
Guanine nucleotide-binding protein G2002
Fatty acid-binding protein 50314
Fatty acid-binding protein 50022
Mitogen-activated protein kinase 110101
Mitogen-activated protein kinase 140101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE190019
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
mitogen-activated protein kinase 14004
survival motor neuron protein isoform d8008
Histone deacetylase 30404
Histone deacetylase 40404
Histone deacetylase 10505
Histone deacetylase 70404
Histone deacetylase 20404
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80505
NAD-dependent protein deacylase sirtuin-5, mitochondrial0202
Histone deacetylase 60505
Histone deacetylase 90404
Histone deacetylase 50404
N-alpha-acetyltransferase 500022
AR protein360036
estrogen nuclear receptor alpha400040
67.9K protein5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a130013
thyroid hormone receptor beta isoform 2210021
Cellular tumor antigen p53280028
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma220022
nuclear receptor subfamily 1, group I, member 3200020
cytochrome P450 family 3 subfamily A polypeptide 4170017
glucocorticoid receptor [Homo sapiens]280028
estrogen-related nuclear receptor alpha300030
pregnane X nuclear receptor160016
nuclear factor erythroid 2-related factor 2 isoform 29009
heat shock protein beta-18008
tumor susceptibility gene 101 protein2002
lamin isoform A-delta10270027
Voltage-dependent calcium channel gamma-2 subunit100010
Bile salt export pump018018
Cyclin-dependent kinase 10101
Heat shock protein HSP 90-beta0101
Glutamate receptor 2103114
Xanthine dehydrogenase/oxidase0303
TAR DNA-binding protein 43100010
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 58008
Ataxin-2110011
GLI family zinc finger 3260026
retinoic acid nuclear receptor alpha variant 1270027
cytochrome P450 2D67007
peroxisome proliferator-activated receptor delta120012
thyroid hormone receptor beta isoform a120012
histone acetyltransferase KAT2A isoform 1100010
lethal factor (plasmid)150015
Solute carrier family 22 member 200707
Solute carrier family 22 member 60707
Chain A, TYROSYL-DNA PHOSPHODIESTERASE170017
Carbonic anhydrase 105015
Carbonic anhydrase 205015
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0003
Glutamate receptor ionotropic, NMDA 1 013219
Proton-coupled amino acid transporter 1010011
Adenosine deaminase0001
Carbonic anhydrase 40003
interleukin 84004
thyroid stimulating hormone receptor140014
estrogen receptor 2 (ER beta)150015
progesterone receptor120012
IDH17007
euchromatic histone-lysine N-methyltransferase 2310031
Bloom syndrome protein isoform 1150015
transcriptional regulator ERG isoform 32002
ras-related protein Rab-9A3003
nuclear factor erythroid 2-related factor 2 isoform 1200020
ATP-binding cassette sub-family C member 3011011
Multidrug resistance-associated protein 4011012
Polyphenol oxidase 20203
Hypoxanthine-guanine phosphoribosyltransferase0002
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase 0101
Adenosine receptor A2a0011
Nuclear receptor ROR-gamma0101
Xanthine dehydrogenase/oxidase0214
Purine nucleoside phosphorylase0011
Canalicular multispecific organic anion transporter 1012012
Shiga toxin subunit A0202
Histamine H3 receptor0101
Chain A, Beta-lactamase5005
Chain A, HADH2 protein100010
Chain B, HADH2 protein100010
Chain A, 2-oxoglutarate Oxygenase110011
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
Chain A, Cruzipain5005
Luciferase120012
15-lipoxygenase, partial5005
WRN1001
phosphopantetheinyl transferase180018
hypoxia-inducible factor 1 alpha subunit7007
SMAD family member 22002
GLS protein110011
SMAD family member 32002
Microtubule-associated protein tau110011
thioredoxin glutathione reductase4004
aldehyde dehydrogenase 1 family, member A1240024
regulator of G-protein signaling 4130013
retinoid X nuclear receptor alpha150015
farnesoid X nuclear receptor140014
peroxisome proliferator activated receptor gamma170017
vitamin D (1,25- dihydroxyvitamin D3) receptor130013
activating transcription factor 6100010
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)140014
Caspase-74004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1100010
phospholipase A2 precursor0101
caspase-34004
cysteine protease ATG4B isoform a0101
lethal(3)malignant brain tumor-like protein 1 isoform I4004
cytochrome P450 3A4 isoform 1100010
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Gamma-aminobutyric acid receptor subunit pi107118
Free fatty acid receptor 10022
Polyunsaturated fatty acid lipoxygenase ALOX15B6006
Prostaglandin G/H synthase 1 0405
Nuclear receptor subfamily 1 group I member 20033
Trypsin0404
Coagulation factor VII0404
Aromatase0404
Tissue factor0505
Gamma-aminobutyric acid receptor subunit beta-1107118
Gamma-aminobutyric acid receptor subunit delta107118
Gamma-aminobutyric acid receptor subunit gamma-2107118
Gamma-aminobutyric acid receptor subunit alpha-5107118
Gamma-aminobutyric acid receptor subunit alpha-3107118
Prostaglandin G/H synthase 10404
Gamma-aminobutyric acid receptor subunit gamma-1107118
Gamma-aminobutyric acid receptor subunit alpha-2107118
Gamma-aminobutyric acid receptor subunit alpha-4107118
Gamma-aminobutyric acid receptor subunit gamma-3107118
Gamma-aminobutyric acid receptor subunit alpha-6107118
Peroxisome proliferator-activated receptor gamma0011
Histamine H2 receptor9009
Gamma-aminobutyric acid receptor subunit alpha-1108119
Gamma-aminobutyric acid receptor subunit beta-3107118
Gamma-aminobutyric acid receptor subunit beta-2107118
Prostaglandin G/H synthase 20405
Free fatty acid receptor 40022
GABA theta subunit107118
Gamma-aminobutyric acid receptor subunit epsilon107118
ATP-dependent phosphofructokinase120012
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
cellular tumor antigen p53 isoform a6006
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
nuclear receptor ROR-gamma isoform 19009
caspase-1 isoform alpha precursor2002
Fatty-acid amide hydrolase 10101
60 kDa chaperonin0202
60 kDa heat shock protein, mitochondrial0202
Prostaglandin G/H synthase 20416
Nuclear receptor subfamily 4 group A member 20022
10 kDa heat shock protein, mitochondrial0202
Calmodulin 0113
Disintegrin and metalloproteinase domain-containing protein 171001
Solute carrier organic anion transporter family member 2A10001
Thiosulfate sulfurtransferase0202
Lanosterol 14-alpha demethylase0101
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Solute carrier organic anion transporter family member 1B30405
Cytosolic phospholipase A2 gamma0101
Transient receptor potential cation channel subfamily V member 20101
Solute carrier organic anion transporter family member 1B10506
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0033
NFKB1 protein, partial4004
alpha-galactosidase3003
cytochrome P450 2C19 precursor4004
chromobox protein homolog 1160016
muscarinic acetylcholine receptor M19009
Cytochrome P450 3A40517
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
Neutral amino acid transporter A0404
Neutral amino acid transporter B(0)0404
Carbonic anhydrase-like protein, putative0008
Amino acid transporter0404
Chain A, Ferritin light chain7007
arylsulfatase A8008
Metabotropic glutamate receptor 60124
Excitatory amino acid transporter 40202
Glutamate transporter homolog0011
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0303
Excitatory amino acid transporter 10304
Excitatory amino acid transporter 20304
Excitatory amino acid transporter 30304
Glutamate receptor ionotropic, NMDA 2A 011217
Glutamate receptor ionotropic, NMDA 2B011217
Glutamate receptor ionotropic, NMDA 2C011217
Metabotropic glutamate receptor 10124
Metabotropic glutamate receptor 20124
Glutamate receptor ionotropic, NMDA 2D011217
Glutamate receptor ionotropic, NMDA 3B011217
Glutamate receptor ionotropic, NMDA 3A011217
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
hypothetical protein, conserved2002
EWS/FLI fusion protein7007
glucocerebrosidase2002
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0303
Fatty acid-binding protein, liver0404
Integrin beta-33115
Myeloperoxidase0202
Prostaglandin G/H synthase 10303
Seed linoleate 13S-lipoxygenase-10202
Integrin alpha-IIb3115
Glutathione hydrolase 1 proenzyme0101
Adenosine receptor A10205
Adenosine receptor A2a0104
Substance-P receptor0202
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma3115
Ras-related protein Rab-2A0011
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0303
Sigma non-opioid intracellular receptor 10415
Sigma non-opioid intracellular receptor 10112
Chain A, Oxygen-insensitive Nad(p)h Nitroreductase0101
Chain B, Oxygen-insensitive Nad(p)h Nitroreductase0101
acetylcholinesterase100010
D-amino-acid oxidase0011
Neuronal acetylcholine receptor subunit alpha-40303
Neuronal acetylcholine receptor subunit beta-20303
Tyrosinase0101
D-amino-acid oxidase0213
Metabotropic glutamate receptor 50124
Alpha-glucosidase MAL120101
Monocarboxylate transporter 10002
Beta-lactamase 0112
D-aspartate oxidase0101
Serine racemase0202
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent GABA transporter 20101
Chain A, Putative fructose-1,6-bisphosphate aldolase6006
Caspase-71001
Inositol monophosphatase 13003
Carbonic anhydrase 40408
Chain A, serum paraoxonase0101
Carbonic anhydrase 120105
Carbonic anhydrase 30105
Neutrophil cytosol factor 10101
Carbonic anhydrase 60105
Carbonic anhydrase 5A, mitochondrial0307
Carbonic anhydrase 70105
Carbonic anhydrase 90307
Carbonic anhydrase 130103
Poly [ADP-ribose] polymerase tankyrase-20101
Carbonic anhydrase 140105
Carbonic anhydrase 5B, mitochondrial0105
GALC protein1001
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Proteasome subunit beta type-110001
ATAD5 protein, partial6006
Fumarate hydratase6006
Thrombopoietin2002
Smad35005
caspase 7, apoptosis-related cysteine protease4004
NADPH oxidase 10101
G6006
polyprotein6006
Snq2p0001
caspase-34004
Adenylate cyclase type 1 0202
thyroid stimulating hormone receptor7007
Histone H2A.x6006
Spike glycoprotein0134
Replicase polyprotein 1ab0134
cytochrome P450 2D6 isoform 13003
D(1A) dopamine receptor3003
potassium voltage-gated channel subfamily H member 2 isoform d8008
histone deacetylase 9 isoform 31001
atrial natriuretic peptide receptor 2 precursor2002
serine/threonine-protein kinase mTOR isoform 14004
peripheral myelin protein 22120012
M-phase phosphoprotein 87007
Proteasome subunit alpha type-70001
Solute carrier family 22 member 1 0507
Transmembrane protease serine 20134
Glutamate receptor ionotropic, NMDA 2D0303
Transient receptor potential cation channel subfamily V member 10101
Glutamate receptor ionotropic, NMDA 3B0303
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Bile salt export pump0404
5-hydroxytryptamine receptor 40404
Potassium channel subfamily K member 20101
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 6006
Albumin0011
Albumin0011
Major prion protein0011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Receptor tyrosine-protein kinase erbB-20101
Major prion protein0011
Cytochrome P450 1A20022
Tyrosine-protein kinase Fyn0101
Procathepsin L0134
Aldo-keto reductase family 1 member B10505
Muscarinic acetylcholine receptor M20404
Muscarinic acetylcholine receptor M40404
ATP-dependent translocase ABCB10406
Muscarinic acetylcholine receptor M10202
Muscarinic acetylcholine receptor M30202
Muscarinic acetylcholine receptor M40202
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M50202
Muscarinic acetylcholine receptor M50404
Alpha-2A adrenergic receptor0404
Replicase polyprotein 1a0134
Replicase polyprotein 1ab0134
Replicase polyprotein 1ab0134
Cys-loop ligand-gated ion channel0101
Calmodulin-10213
Replicase polyprotein 1ab0134
Cytochrome P450 2D60123
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M10404
Cytochrome P450 2C9 0415
Polyunsaturated fatty acid lipoxygenase ALOX150101
Angiotensin-converting enzyme0404
D(2) dopamine receptor0506
5-hydroxytryptamine receptor 2A0303
Alpha-1B adrenergic receptor0404
Sphingomyelin phosphodiesterase0101
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
D0303
D(3) dopamine receptor0303
5-hydroxytryptamine receptor 1A0718
Alpha-2B adrenergic receptor0202
D(2) dopamine receptor0101
Muscarinic acetylcholine receptor M30404
Proteasome subunit beta type-10001
Substance-K receptor0202
D(1A) dopamine receptor0405
D(4) dopamine receptor0304
D(1B) dopamine receptor0102
Adenylate cyclase type 30202
Alpha-2C adrenergic receptor0202
UDP-glucuronosyltransferase 1A40104
Alpha-2A adrenergic receptor0202
Alpha-1D adrenergic receptor0303
Sodium-dependent noradrenaline transporter 0404
Sodium-dependent dopamine transporter0202
Histamine H2 receptor0404
Alpha-1D adrenergic receptor0404
D(1B) dopamine receptor0303
Proteasome subunit alpha type-10001
Proteasome subunit alpha type-20001
Proteasome subunit alpha type-30001
Proteasome subunit alpha type-40001
Adenylate cyclase type 20202
Adenylate cyclase type 40202
Proteasome subunit beta type-80001
Proteasome subunit beta type-90001
Proteasome subunit alpha type-50001
Proteasome subunit beta type-40001
Proteasome subunit beta type-60001
Proteasome subunit beta type-50001
5-hydroxytryptamine receptor 2A0404
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0404
Trypanothione reductase0202
D(4) dopamine receptor0303
5-hydroxytryptamine receptor 2B0202
Histamine H1 receptor0112
Sodium-dependent serotonin transporter0303
Melanocortin receptor 40202
5-hydroxytryptamine receptor 7 0202
Melanocortin receptor 50202
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 70202
Histamine H1 receptor0516
Mu-type opioid receptor0415
D(3) dopamine receptor0506
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 4 subunit alpha0304
Adenylate cyclase type 80202
Proteasome subunit beta type-100001
Delta-type opioid receptor0404
Kappa-type opioid receptor0404
5-hydroxytryptamine receptor 2B0606
Melanocortin receptor 30202
Alpha-1A adrenergic receptor0404
Proteasome subunit beta type-30001
Proteasome subunit beta type-20001
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 60404
5-hydroxytryptamine receptor 70101
Cytochrome P450 2J20202
Gastrin/cholecystokinin type B receptor0101
Spike glycoprotein5139
Proteasome subunit alpha type-60012
D(2) dopamine receptor0405
Aldehyde oxidase 10101
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Sodium-dependent dopamine transporter 0202
Adenylate cyclase type 60202
Adenylate cyclase type 50202
Glutamate receptor ionotropic, NMDA 10404
Aldehyde oxidase0202
Potassium voltage-gated channel subfamily H member 20707
Glutamate receptor ionotropic, NMDA 2A0404
Glutamate receptor ionotropic, NMDA 2B0404
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0202
Glutamate receptor ionotropic, NMDA 2C0303
Sodium channel protein type 9 subunit alpha0202
Nuclear receptor subfamily 3 group C member 3 0404
Adenylyl cyclase 7 0202
Proteasome subunit alpha-type 80001
Glutamate receptor ionotropic, NMDA 3A0303
Inositol hexakisphosphate kinase 16006
D0101
Sodium channel protein type 2 subunit alpha0303
Proteasome subunit beta type-70001
Angiotensin-converting enzyme 2 0134
Sodium channel protein type 3 subunit alpha0303
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Histamine H3 receptor0101
Sodium channel protein type 10 subunit alpha0101
cytochrome P450 2C9, partial6006
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10204
Solute carrier family 22 member 20102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70202
Solute carrier family 22 member 10304
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20304
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, Proto-oncogene Tyrosine-protein Kinase Src0101
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain A, N5-carboxyaminoimidazole ribonucleotide mutase0011
Chain B, N5-carboxyaminoimidazole ribonucleotide mutase0011
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50101
perilipin-10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Beta-lactamase0101
Proto-oncogene tyrosine-protein kinase Src0101
3-dehydroquinate dehydratase0011
ATP-citrate synthase 0102
Ribonuclease T0001
Cell death-related nuclease 40001
3-dehydroquinate dehydratase0011
Prolyl 4-hydroxylase0404
Alpha-ketoglutarate-dependent dioxygenase FTO0303
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
General amino-acid permease GAP10001
Histone acetyltransferase p3000101
Histone acetyltransferase KAT2B0101
Histone acetyltransferase KAT50101
Sodium- and chloride-dependent creatine transporter 10101
glp-1 receptor, partial6006
pregnane X receptor5005
PPM1D protein3003
P531001
RPL19A0011
aryl hydrocarbon receptor6006
NPC intracellular cholesterol transporter 1 precursor1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
heat shock protein HSP 90-alpha isoform 20001
transactivating tegument protein VP16 [Human herpesvirus 1]0202
COUP transcription factor 2 isoform a0101
Glucose transporter0101
Hexose transporter 1 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Solute carrier family 2, facilitated glucose transporter member 10101
Alpha-synuclein2103
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0527
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40202
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10314
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
huntingtin isoform 23003
chaperonin GroEL1001
Sodium-dependent noradrenaline transporter0101
Glycogen phosphorylase, brain form0101
Glycogen phosphorylase, muscle form0101
Endothelin receptor type B0101
Endothelin receptor type B0101
5-hydroxytryptamine receptor 2C 0101
UDP-glucuronosyltransferase 1A30001
D(2) dopamine receptor0101
Sodium-dependent serotonin transporter0101
Histone-lysine N-methyltransferase SETD70202
Transporter0101
endonuclease IV7007
LMP1 [Human herpesvirus 4]0002
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
nuclear receptor coactivator 3 isoform a0101
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0101
Thymidine kinase0101
Thymidylate synthase0203
Thymidine kinase0101
Deoxycytidine kinase0003
Probable deoxycytidylate deaminase0002
Cytidine deaminase0205
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Deoxycytidine kinase0001
Chain A, Breast cancer type 1 susceptibility protein1001
runt-related transcription factor 1 isoform AML1b2002
core-binding factor subunit beta isoform 22002
histone-lysine N-methyltransferase 2A isoform 2 precursor4004
NADH-ubiquinone oxidoreductase chain 40001
72 kDa type IV collagenase0101
DNA topoisomerase 2-alpha0001
Carbonyl reductase [NADPH] 10001
Glutamate receptor 11315
Glutamate receptor 31315
Glutamate receptor 41315
Platelet-activating factor receptor1001
Multidrug resistance-associated protein 1 0203
Reverse transcriptase/RNaseH 0112
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Chain A, Odorant binding protein0011
Chain B, Odorant binding protein0011
Thymidine kinase 2 0101
AAA family ATPase 0002
Endothelin-1 receptor0101
Amine oxidase [flavin-containing] A0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0213
Kappa-type opioid receptor0101
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0303
Sigma non-opioid intracellular receptor 10303
muscleblind-like protein 1 isoform 13003
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit alpha-30202
Gamma-aminobutyric acid receptor subunit alpha-10213
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20213
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit beta-30213
Gamma-aminobutyric acid receptor subunit alpha-50213
Gamma-aminobutyric acid receptor subunit alpha-30213
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit epsilon0202
Gamma-aminobutyric acid receptor subunit alpha-60202
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
Chain A, Uracil Phosphoribosyltransferase0101
Skn7p0001
nonstructural protein 15005
peripheral myelin protein 22 isoform 16006
hemoglobin subunit beta1001
Vpr1001
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1203
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
lysosomal alpha-glucosidase preproprotein2002
DNA polymerase beta1001
Thymidylate synthase0202
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10303
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Chain A, DEOXYNUCLEOSIDE KINASE0101
Equilibrative nucleoside transporter 10303
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
Metabotropic glutamate receptor 80202
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10101
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, kainate 50101
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Protein-glutamine gamma-glutamyltransferase 20101
Chain A, Glutamine Binding Protein0011
Asc-type amino acid transporter 10101
Chain A, Protein (aspartate Aminotransferase)0022
Chain A, Aspartate Aminotransferase0022
Solute carrier family 22 member 60102
Solute carrier family 22 member 70001
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 109010
Olfactory receptor 51E20033
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0202
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Guanine deaminase0001
Chain A, HISTIDINE-BINDING PROTEIN0011
Plasma kallikrein0004
Histidine-binding periplasmic protein0011
Carbonic anhydrase0004
Carbonic anhydrase0004
Glutaminyl-peptide cyclotransferase0101
Carbonic anhydrase 0004
Carbonic anhydrase0004
Carbonic anhydrase0206
Carbonic anhydrase 0004
Carbonic anhydrase 150004
Carbonic anhydrase 130003
ClpP1001
Solute carrier family 22 member 80001
cytochrome P450 2C9 precursor3003
neuropeptide S receptor isoform A4004
Uracil nucleotide/cysteinyl leukotriene receptor0202
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
Sodium/myo-inositol cotransporter 20101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
Acetylcholinesterase0202
Rap guanine nucleotide exchange factor 34004
Cholinesterase0202
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0303
Intestinal-type alkaline phosphatase0303
Phospholipase A-2-activating protein0303
Sterol O-acyltransferase 10101
Fatty acid-binding protein, heart0202
Tyrosine-protein phosphatase non-receptor type 70101
Sterol O-acyltransferase 10101
Aldo-keto reductase family 1 member C30101
Dual specificity protein phosphatase 30101
Peroxisome proliferator-activated receptor alpha2013
Translocator protein0315
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
nuclear receptor subfamily 1, group I, member 22002
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Serine racemase0101
ATP-dependent translocase ABCB10101
Translocator protein0314
UDP-glucuronosyltransferase 2B70204
UDP-glucuronosyltransferase 1-60102
ATP-dependent translocase ABCB10101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 2B10 0101
Toll-like receptor 20101
Peroxisome proliferator-activated receptor delta0001
Dynamin-10101
G-protein coupled receptor 840112
Lysine-specific demethylase 4C0101
Angiotensin-converting enzyme 0202
Solute carrier family 15 member 10112
Solute carrier family 15 member 20101
Ornithine transcarbamylase, mitochondrial0101
Nociceptin receptor0101
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain A, ARGINASE 10101
Chain A, Arginase 10101
Chain A, ARGINASE 10101
Chain A, L-ARGININE\\:GLYCINE AMIDINOTRANSFERASE0101
Solute carrier family 2, facilitated glucose transporter member 90112
Tyrosine-protein phosphatase non-receptor type 10101
Olfactory receptor class A-like protein 10011
Tyrosine-protein kinase Lck0011
Prolyl 4-hydroxylase subunit alpha-10101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
E3 ubiquitin-protein ligase XIAP0101
SLC16A10 protein0003
Large neutral amino acids transporter small subunit 1 0101
Monocarboxylate transporter 100003
Estrogen receptor 10101
Parkin3003
fMet-Leu-Phe receptor0101
Prostaglandin G/H synthase 2 0101
Prostaglandin G/H synthase 1 0101
Cyclooxygenase-2 0101
Solute carrier family 22 member 80101
Gamma-aminobutyric acid 0101
atrial natriuretic peptide receptor 1 precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Dihydrofolate reductase 0101
Sodium channel protein type 2 subunit alpha0101
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Chain A, Alkaline Phosphatase0101
Chain A, ALKALINE PHOSPHATASE0101
DNA polymerase III, partial1001
bromodomain adjacent to zinc finger domain 2B4004
Fe(3+)-Zn(2+) purple acid phosphatase0101
Fatty acid-binding protein, liver0101
prostaglandin E2 receptor EP2 subtype0001
Nuclear receptor subfamily 1 group I member 3 0101
luciferase0001
Estrogen receptor0202
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nociceptin receptor0011
Estrogen receptor beta0202
Glutamate 5-kinase0001
Free fatty acid receptor 30011
Free fatty acid receptor 20112
Free fatty acid receptor 20011
Pyridoxal kinase0001
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Solute carrier organic anion transporter family member 2A10101
Lysine-specific demethylase 4E0202
Advanced glycosylation end product-specific receptor0011
Beta-lactamase 0101
Advanced glycosylation end product-specific receptor0011
Met repressor 0022
Protein arginine N-methyltransferase 50011
Histone H3K27 methylase0001
Phenylethanolamine N-methyltransferase0012
S-adenosylmethionine decarboxylase proenzyme0102
Protein-L-isoaspartate(D-aspartate) O-methyltransferase0101
Catechol O-methyltransferase0001
Protein arginine N-methyltransferase 10101
Methylosome protein 500011
Pyruvate kinase PKM0011
Free fatty acid receptor 30011
Delta-aminolevulinic acid dehydratase0101
NADP-dependent malic enzyme, mitochondrial0001
Solute carrier family 13 member 30101
Egl nine homolog 10112
Methyl-accepting chemotaxis protein NahY0011
Cytochrome P450 3A50101
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Thymidine phosphorylase0101
Chain A, Nuclear Receptor ROR-beta0101
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
thyrotropin-releasing hormone receptor1001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
Adenosine receptor A30202
Retinoic acid receptor alpha0227
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2C190011
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
Cellular retinoic acid-binding protein 10011
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Dihydrofolate reductase0202
Stromelysin-10101
Indoleamine 2,3-dioxygenase 10102
Tryptophan 2,3-dioxygenase0102
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
Chain A, Uracil-DNA Glycosylase0101
Protein cereblon0404
Urease subunit alpha0101
Urease subunit beta0101
CAD protein0001
Chain A, Cytidine Deaminase0101
Sodium/nucleoside cotransporter 10202
Sodium/nucleoside cotransporter 20202
Equilibrative nucleoside transporter 20202
Uridine-cytidine kinase 1 0001
Solute carrier family 28 member 30202
Chain A, Arginase 10101
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]