Cystic Angiomatosis Of Bone, Diffuse

Syndromes of bone destruction where the cause is not obvious such as neoplasia, infection, or trauma. The destruction follows various patterns: massive (Gorham disease), multicentric (HAJDU-CHENEY SYNDROME), or carpal/tarsal.

Synonyms(8)

Synonym
Osteolysis, Essential
Gorham's Disease
Gorham Disease
Osteolysis, Idiopathic Multicentric
Cystic Angiomatosis Of Bone, Diffuse
Disappearing Bone Disease
Osteolysis, Massive
Gorham-Stout Disease

Research Excerpts

Overview

Excerpt	Reference
""Disappearing bone disease" is a rare entity that is characterized by extensive osteolysis associated with hemangiomatosis."	( Carneiro, RS; Steglich, V, 1987)
"Gorham disease is a rare condition characterized by intraosseous neoplastic proliferation of hemangiomatous tissue with progressive, massive osteolysis."	( Chen, A; Chen, CY; Chin, SC; Hsueh, CJ; Juan, CJ; Lo, CP, 2004)
"Gorham's disease is a rare disorder characterized by spontaneous and progressive osteolysis of one or more skeletal bones."	( Fedele, S; Lanza, A; Lo Russo, L; Marenzi, G; Mignogna, MD; Sammartino, G, 2005)
"Gorham's disease is a rare benign cause of progressive massive idiopathic osteolysis."	( Bandyopadhyay, A; Chattopadhyay, P; Das, S; Kundu, AJ, 2009)
"Gorham's disease is a rare musculoskeletal disease of unknown etiology characterized by progressive osteolysis and massive bone destruction."	( Abbasian, M; Esmailiejah, AA; Kamalian, N, 2013)
"Gorham's disease is progressive in most patients; yet it can be self-limiting in a few reported cases."	( Al-Hussaini, M; Attili, A; Ellati, R; Haddad, H; Shehadeh, A, 2016)

Actions

Excerpt	Reference
"A rare case of Gorham's disease affecting the radius in a 46-year-old woman is presented."	( Ansari, AN; Forrester, DM; Gleason-Jordan, I; Greenspan, A; Kimura, RL; Spieth, ME, 1997)

Treatment

Excerpt	Reference
"The treatment of massive osteolysis with lymphangioma and/or hemangioma (Gorham-Stout syndrome) has been controversial."	( Kanazawa, T; Kuwano, H; Morikawa, A; Ogawa, C; Suzuki, M; Suzuki, N; Takahashi, A; Tsuchida, Y; Watanabe, H, 2005)

Research

Studies (154)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	60 (38.96)	23.3326
1990's	18 (11.69)	12.5806
2000's	19 (12.34)	18.1394
2010's	43 (27.92)	28.8240
2020's	14 (9.09)	9.53

Drug	Relationship Strength	Studies	Trials
adenine	low	1	0
chlorine	low	1	0
salicylic acid	low	1	0
alendronate	low	4	0
busulfan	low	1	0
fentanyl	low	1	0
fluorouracil	low	1	0
indomethacin	low	1	0
oxyphenbutazone	low	1	0
pamidronate	low	4	0
propranolol	low	3	0
sodium fluoride	low	1	0
thalidomide	low	1	0
corticosterone	low	1	0
hydroxyproline	low	2	0
thyroxine	low	1	0
aldosterone	low	1	0
penicillamine	low	1	0
prednisone	low	4	0
ethinyl estradiol	low	1	0
edetic acid	low	1	0
vinyl chloride	low	1	0
acrylonitrile	low	1	0
pyrroles	low	1	0
pyrazines	low	1	0
limestone	low	1	0
fusarium	low	1	0
titanium	medium	3	1
americium	low	1	0
chromium	low	1	0
zirconium	low	1	0
trolamine salicylate	low	11	0
clodronic acid	low	1	0
fluorides	low	1	0
paclitaxel	low	1	0
fluorodeoxyglucose f18	low	2	0
zoledronic acid	low	16	0
dracorhodin	low	1	0
technetium tc 99m hydroxymethylene diphosphonate	low	2	0
methotrexate	low	1	0
proline	low	1	0
technetium tc 99m (sn)methylenediphosphonate	low	1	0
bortezomib	low	1	0
fibrin	low	1	0
picibanil	low	3	0
propylthiouracil	low	1	0
succimer	low	1	0
fusafungin	low	1	0
osteoprotegerin	low	1	0
calcitriol	low	1	0
amphotericin b	low	2	0
sirolimus	medium	11	1
su 11248	low	1	0
antimony	low	1	0
phosphorus	low	4	0
24,25-dihydroxyvitamin d 3	low	1	0
everolimus	low	1	0
technetium tc 99m diphosphonate	low	2	0
trametinib	low	1	0
acid phosphatase	low	2	0
jaw	low	3	0
pci 32765	low	1	0
piperidines	low	1	0
demeclocycline	low	1	0
technetium tc 99m sulfur colloid	low	1	0
technetium tc 99m medronate	low	8	0
technetium tc 99m dimercaptosuccinic acid	low	2	0
pyrimidinones	low	1	0

Protein Targets (1,284)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
RAR-related orphan receptor gamma	12	0	0	12
ATAD5 protein, partial	5	0	0	5
GLS protein	5	0	0	5
Microtubule-associated protein tau	8	0	0	8
Smad3	4	0	0	4
aldehyde dehydrogenase 1 family, member A1	10	0	0	10
thyroid stimulating hormone receptor	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	10	0	0	10
progesterone receptor	10	0	0	10
EWS/FLI fusion protein	13	0	0	13
retinoic acid nuclear receptor alpha variant 1	10	0	0	10
retinoid X nuclear receptor alpha	14	0	0	14
estrogen-related nuclear receptor alpha	16	0	0	16
estrogen nuclear receptor alpha	21	0	0	21
peroxisome proliferator activated receptor gamma	13	0	0	13
aryl hydrocarbon receptor	5	0	0	5
chromobox protein homolog 1	8	0	0	8
thyroid hormone receptor beta isoform 2	15	0	0	15
peripheral myelin protein 22	10	0	0	10
cytochrome P450 3A4 isoform 1	4	0	0	4
Gamma-aminobutyric acid receptor subunit pi	4	1	1	6
ATP-binding cassette sub-family C member 3	0	14	0	14
Multidrug resistance-associated protein 4	0	14	0	15
Solute carrier family 22 member 6	0	5	0	5
Carbonic anhydrase 12	0	4	0	4
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	6	0	6
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Bile salt export pump	0	21	0	21
Cytochrome P450 2B1	0	1	0	2
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	8	0	8
Carbonic anhydrase 2	0	8	1	9
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	0	1	2
Cytochrome P450 1A2	0	3	0	5
Prostaglandin G/H synthase 1	0	6	0	7
Carbonic anhydrase 3	0	3	0	3
Cytochrome P450 3A4	0	8	0	10
Cytochrome P450 2D6	0	5	0	5
Cytochrome P450 2C9	0	8	0	10
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	1	1	6
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	4	1	1	6
Gamma-aminobutyric acid receptor subunit gamma-2	4	1	1	6
UDP-glucuronosyltransferase 1-6	0	1	0	2
Glutamate receptor 2	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-5	4	1	1	6
Gamma-aminobutyric acid receptor subunit alpha-3	4	1	1	6
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	3	0	5
Carbonic anhydrase 4	0	5	0	5
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	4	1	1	6
Gamma-aminobutyric acid receptor subunit alpha-2	4	1	1	6
Gamma-aminobutyric acid receptor subunit alpha-4	4	1	1	6
Gamma-aminobutyric acid receptor subunit gamma-3	4	1	1	6
Gamma-aminobutyric acid receptor subunit alpha-6	4	1	1	6
Carbonic anhydrase 5A, mitochondrial	0	3	0	3
Prostaglandin G/H synthase 2	0	4	2	7
Carbonic anhydrase 7	0	3	0	3
Nuclear receptor ROR-gamma	6	0	0	6
Cytochrome P450 2J2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	4	1	1	6
Gamma-aminobutyric acid receptor subunit beta-3	4	1	1	6
Gamma-aminobutyric acid receptor subunit beta-2	4	1	1	6
Carbonic anhydrase 9	0	4	0	4
GABA theta subunit	4	1	1	6
Canalicular multispecific organic anion transporter 1	0	14	0	14
Carbonic anhydrase 15	0	5	0	5
Carbonic anhydrase 13	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	4	1	1	6
Carbonic anhydrase 14	0	4	0	4
Carbonic anhydrase 5B, mitochondrial	0	3	0	3
toxin B	0	0	0	1
GLI family zinc finger 3	7	0	0	7
Cellular tumor antigen p53	13	0	0	13
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	7	0	0	7
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
TDP1 protein	19	0	0	19
AR protein	16	0	0	16
cytochrome P450 family 3 subfamily A polypeptide 4	10	0	0	10
glucocorticoid receptor [Homo sapiens]	15	0	0	15
pregnane X nuclear receptor	13	0	0	13
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 2	7	0	0	7
heat shock protein beta-1	6	0	0	6
importin subunit beta-1 isoform 1	3	0	0	3
snurportin-1	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
lamin isoform A-delta10	15	0	0	15
Cyclin-dependent kinase 1	0	1	5	6
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
TAR DNA-binding protein 43	5	0	0	5
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	3	1	4
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	6	0	0	6
thyroid hormone receptor beta isoform a	6	0	0	6
geminin	16	0	0	16
Sex hormone-binding globulin	0	0	3	3
Corticosteroid-binding globulin	0	2	0	2
Mineralocorticoid receptor	0	1	3	4
Androgen receptor	0	4	0	4
Mineralocorticoid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
Guanine nucleotide-binding protein G	3	0	0	3
Chain A, farnesyl pyrophosphate synthase	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	4	0	5
Farnesyl pyrophosphate synthase	0	6	0	6
Acetylcholinesterase	0	4	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	2	0	2
Farnesyl pyrophosphate synthase	0	4	0	4
Farnesyl pyrophosphate synthase	0	2	0	2
Chain A, HADH2 protein	4	0	0	4
Chain B, HADH2 protein	4	0	0	4
Chain A, Cruzipain	2	0	0	2
interleukin 8	5	0	0	5
phosphopantetheinyl transferase	5	0	0	5
farnesoid X nuclear receptor	9	0	0	9
peroxisome proliferator-activated receptor delta	9	0	0	9
vitamin D (1,25- dihydroxyvitamin D3) receptor	12	0	0	12
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 1	14	0	0	14
Cytochrome P450 2C19	0	5	0	6
Potassium voltage-gated channel subfamily H member 2	0	8	0	8
Aurora kinase B	0	2	5	7
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	4
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
Fumarate hydratase	6	0	0	6
PPM1D protein	5	0	0	5
caspase 7, apoptosis-related cysteine protease	2	0	0	2
estrogen receptor 2 (ER beta)	7	0	0	7
polyprotein	6	0	0	6
caspase-3	2	0	0	2
nuclear receptor subfamily 1, group I, member 2	2	0	0	2
Histone H2A.x	5	0	0	5
Caspase-7	2	0	0	2
caspase-3	2	0	0	2
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
Histone deacetylase 3	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Prothrombin	0	1	0	1
Chymotrypsinogen A	0	2	0	2
Interferon beta	9	0	0	9
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	1	0	1
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	2	0	3
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
26S proteasome regulatory subunit 6B	0	1	5	6
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
Histone deacetylase 1	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Histone deacetylase 2	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Histone deacetylase 8	0	1	0	1
Histone deacetylase 6	0	1	0	1
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
15-lipoxygenase, partial	2	0	0	2
apical membrane antigen 1, AMA1	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
lethal factor (plasmid)	2	0	0	2
Matrix metalloproteinase-9	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Chain A, Vitamin D Nuclear Receptor	0	0	1	1
Chain A, Beta-lactamase	3	0	0	3
Chain A, Ferritin light chain	2	0	0	2
Vitamin D3 receptor	0	0	1	1
USP1 protein, partial	9	0	0	9
thioredoxin glutathione reductase	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	16	0	0	16
mitogen-activated protein kinase 1	2	0	0	2
nuclear receptor ROR-gamma isoform 1	6	0	0	6
Vitamin D-binding protein	0	0	1	1
Androgen receptor	0	1	1	2
Vitamin D3 receptor	0	1	2	4
Vitamin D3 receptor	0	1	1	3
Retinoic acid receptor RXR-alpha	0	0	3	3
Kappa-type opioid receptor	0	2	1	3
Vitamin D3 receptor	0	0	1	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	0	1	1
Vitamin D3 receptor	0	1	1	2
Transporter	0	1	0	1
Vitamin D3 receptor A	0	0	2	2
Carbonic anhydrase	0	3	0	3
Type IV secretion-like conjugative transfer relaxase protein TraI	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Stromelysin-1	0	2	1	3
Macrophage metalloelastase	0	1	0	1
thioredoxin reductase	9	0	0	9
pregnane X receptor	5	0	0	5
NFKB1 protein, partial	2	0	0	2
GALC protein	1	0	0	1
Thrombopoietin	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3	0	0	3
nonstructural protein 1	3	0	0	3
G	5	0	0	5
IDH1	7	0	0	7
thyroid stimulating hormone receptor	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
survival motor neuron protein isoform d	4	0	0	4
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 1	0	5	0	5
Solute carrier family 22 member 3	0	2	0	2
Solute carrier family 22 member 3	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
C-8 sterol isomerase	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Inositol hexakisphosphate kinase 1	5	0	0	5
Sigma non-opioid intracellular receptor 1	0	5	0	5
Solute carrier family 22 member 2	0	2	0	2
cytochrome P450 2C9, partial	5	0	0	5
dopamine D1 receptor	2	0	0	2
regulator of G-protein signaling 4	1	0	0	1
arylsulfatase A	5	0	0	5
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
flap endonuclease 1	3	0	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	4	0	0	4
DNA polymerase kappa isoform 1	6	0	0	6
M-phase phosphoprotein 8	3	0	0	3
ATP-dependent phosphofructokinase	5	0	0	5
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
hypoxia-inducible factor 1 alpha subunit	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
Eyes absent homolog 2	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	1	0	0	1
Amyloid-beta precursor protein	1	1	0	2
Angiotensin-converting enzyme	0	2	0	2
Histamine H2 receptor	2	0	0	2
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Luciferase	7	0	0	7
67.9K protein	8	0	0	8
activating transcription factor 6	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
urokinase-type plasminogen activator precursor	3	0	0	3
plasminogen precursor	3	0	0	3
urokinase plasminogen activator surface receptor precursor	3	0	0	3
Vpr	2	0	0	2
Estrogen receptor	0	2	1	3
Glucocorticoid receptor	0	4	1	5
Glycine receptor subunit alpha-1	0	4	0	4
Aldo-keto reductase family 1 member B1	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Adenosine receptor A3	0	3	1	4
Neuronal acetylcholine receptor subunit beta-2	1	1	0	2
Alpha-1B adrenergic receptor	0	4	1	5
Glycine receptor subunit beta	0	4	0	4
Cytochrome P450 2B6	0	2	0	3
Glycine receptor subunit alpha-2	0	4	0	4
Sodium-dependent noradrenaline transporter	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Glycine receptor subunit alpha-3	0	4	0	4
Adenosine receptor A2a	0	3	1	4
Sodium-dependent serotonin transporter	0	4	0	4
Mu-type opioid receptor	0	5	2	7
Kappa-type opioid receptor	0	5	1	6
Alpha-1A adrenergic receptor	0	4	1	5
Sulfotransferase 1A1	0	2	1	4
Sodium-dependent dopamine transporter	0	2	0	2
Aldehyde oxidase	0	1	0	1
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Estrogen receptor beta	0	1	1	2
Multidrug and toxin extrusion protein 1	0	2	0	2
Bone morphogenetic protein receptor type-1B	0	0	5	5
Cell division cycle 7-related protein kinase	0	0	5	5
Serine/threonine-protein kinase PLK4	0	1	5	6
ATP-dependent RNA helicase DDX3X	0	0	5	5
Pyridoxal kinase	0	0	5	5
Citron Rho-interacting kinase	0	0	5	5
Serine/threonine-protein kinase Chk1	0	1	5	6
Aurora kinase A	0	1	5	6
Cyclin-G-associated kinase	0	0	5	5
Ephrin type-B receptor 6	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 3	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 2	0	0	5	5
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	5	5
Dynamin-like 120 kDa protein, mitochondrial	0	0	5	5
Eukaryotic translation initiation factor 5B	0	0	4	4
Rho-associated protein kinase 2	0	0	5	5
Serine/threonine-protein kinase ULK1	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	5	5
Ribosomal protein S6 kinase alpha-5	0	0	5	5
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	5	5
Ribosomal protein S6 kinase alpha-4	0	0	5	5
Serine/threonine-protein kinase 16	0	0	5	5
Serine/threonine-protein kinase 10	0	0	5	5
Serine/threonine-protein kinase D3	0	0	5	5
Structural maintenance of chromosomes protein 2	0	0	5	5
Mitogen-activated protein kinase kinase kinase 6	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	5	5
Serine/threonine-protein kinase LATS1	0	0	5	5
Serine/threonine-protein kinase PAK 4	0	2	5	7
Tyrosine-protein kinase ABL1	0	2	7	9
Epidermal growth factor receptor	0	7	6	13
High affinity nerve growth factor receptor	0	0	5	5
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	4	4
ADP/ATP translocase 2	0	0	5	5
Protein kinase C beta type	0	0	5	5
Insulin receptor	0	1	5	6
Tyrosine-protein kinase Lck	0	2	5	7
Tyrosine-protein kinase Fyn	0	2	5	7
Glycogen phosphorylase, liver form	0	0	5	5
Tyrosine-protein kinase Fes/Fps	0	0	5	5
Adenine phosphoribosyltransferase	0	0	5	5
Tyrosine-protein kinase Yes	0	1	5	6
Tyrosine-protein kinase Lyn	0	1	5	6
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	5	7
Insulin-like growth factor 1 receptor	0	0	5	5
Signal recognition particle receptor subunit alpha	0	0	5	5
Cytochrome c1, heme protein, mitochondrial	0	0	5	5
Hepatocyte growth factor receptor	0	1	5	6
Tyrosine-protein kinase HCK	0	2	5	7
Platelet-derived growth factor receptor beta	0	4	5	9
Tyrosine-protein kinase Fgr	0	1	4	5
Serine/threonine-protein kinase A-Raf	0	0	5	5
Glycogen phosphorylase, brain form	0	0	5	5
Breakpoint cluster region protein	0	0	6	6
Serine/threonine-protein kinase pim-1	0	0	5	5
Fibroblast growth factor receptor 1	0	2	5	7
DNA topoisomerase 2-alpha	0	0	5	5
Cyclin-dependent kinase 4	0	0	5	5
ADP/ATP translocase 3	0	0	5	5
Inosine-5'-monophosphate dehydrogenase 2	0	0	5	5
Proto-oncogene tyrosine-protein kinase Src	0	3	5	8
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	5	5
Serine/threonine-protein kinase B-raf	0	0	5	5
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	5	5
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	5	5
Tyrosine-protein kinase Fer	0	0	5	5
Protein kinase C alpha type	0	0	5	5
cAMP-dependent protein kinase catalytic subunit alpha	0	0	5	5
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	5	5
Casein kinase II subunit alpha'	0	0	5	5
Ras-related protein Rab-6A	0	0	5	5
Ephrin type-A receptor 1	0	0	5	5
Multifunctional protein ADE2	0	0	5	5
cAMP-dependent protein kinase catalytic subunit gamma	0	0	4	4
cAMP-dependent protein kinase catalytic subunit beta	0	0	5	5
Ferrochelatase, mitochondrial	0	0	5	5
Ribosomal protein S6 kinase beta-1	0	0	5	5
Tyrosine-protein kinase JAK1	0	2	5	7
Cyclin-dependent kinase 2	0	2	6	8
Beta-adrenergic receptor kinase 1	0	0	5	5
Probable ATP-dependent RNA helicase DDX6	0	0	5	5
Mitogen-activated protein kinase 3	0	0	5	5
MAP/microtubule affinity-regulating kinase 3	0	0	5	5
Deoxycytidine kinase	0	0	5	5
Mitogen-activated protein kinase 1	0	0	5	5
Ephrin type-A receptor 2	0	1	5	6
Ephrin type-B receptor 2	0	0	5	5
Non-receptor tyrosine-protein kinase TYK2	0	0	5	5
UMP-CMP kinase	0	0	4	4
Phosphatidylethanolamine-binding protein 1	0	0	5	5
Wee1-like protein kinase	0	0	5	5
Heme oxygenase 2	0	0	5	5
S-adenosylmethionine synthase isoform type-2	0	0	5	5
DnaJ homolog subfamily A member 1	0	0	5	5
RAC-alpha serine/threonine-protein kinase	0	1	5	6
RAC-beta serine/threonine-protein kinase	0	0	5	5
Dual specificity protein kinase TTK	0	0	5	5
DNA replication licensing factor MCM4	0	0	5	5
Myosin-10	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 2	0	2	5	7
Receptor-type tyrosine-protein kinase FLT3	0	3	5	9
Bone morphogenetic protein receptor type-1A	0	0	5	5
Activin receptor type-1B	0	0	5	5
TGF-beta receptor type-1	0	0	5	5
TGF-beta receptor type-2	0	0	5	5
Electron transfer flavoprotein subunit beta	0	0	4	4
Tyrosine-protein kinase CSK	0	1	5	6
Glycine--tRNA ligase	0	0	5	5
Protein kinase C iota type	0	0	5	5
Exosome RNA helicase MTR4	0	0	5	5
Serine/threonine-protein kinase mTOR	0	3	3	6
Tyrosine-protein kinase Tec	0	1	5	6
Tyrosine-protein kinase ABL2	0	0	5	5
Tyrosine-protein kinase FRK	0	1	5	6
G protein-coupled receptor kinase 6	0	0	5	5
Tyrosine-protein kinase SYK	0	1	5	6
Mitogen-activated protein kinase 8	0	0	5	5
Mitogen-activated protein kinase 9	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 3	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	5	5
Casein kinase I isoform alpha	0	1	4	5
Casein kinase I isoform delta	0	0	5	5
MAP kinase-activated protein kinase 2	0	0	5	5
Elongation factor Tu, mitochondrial	0	0	5	5
Choline-phosphate cytidylyltransferase A	0	0	5	5
Cysteine--tRNA ligase, cytoplasmic	0	0	4	4
Casein kinase I isoform epsilon	0	0	5	5
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	5	5
Dual specificity protein kinase CLK1	0	0	5	5
Dual specificity protein kinase CLK2	0	0	5	5
Dual specificity protein kinase CLK3	0	0	4	4
Glycogen synthase kinase-3 alpha	0	0	5	5
Glycogen synthase kinase-3 beta	0	0	5	5
Cyclin-dependent kinase 7	0	0	5	5
Cyclin-dependent kinase 9	0	0	5	5
Ras-related protein Rab-27A	0	0	5	5
Interleukin-1 receptor-associated kinase 1	0	0	5	5
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Ribosomal protein S6 kinase alpha-3	0	1	5	6
Serine/threonine-protein kinase Nek2	0	1	5	6
Serine/threonine-protein kinase Nek3	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 6	0	0	5	5
Serine/threonine-protein kinase PLK1	0	2	5	7
LIM domain kinase 1	0	0	5	5
LIM domain kinase 2	0	0	5	5
Mitogen-activated protein kinase 10	0	0	5	5
Tyrosine--tRNA ligase, cytoplasmic	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-1	0	0	5	6
Ephrin type-B receptor 3	0	0	5	5
Ephrin type-A receptor 5	0	0	5	5
Ephrin type-B receptor 4	0	1	5	6
Ephrin type-A receptor 4	0	0	5	5
Adenylate kinase 2, mitochondrial	0	0	5	5
Adenosine kinase	0	0	5	5
Ras-related protein Rab-10	0	0	5	5
Actin-related protein 3	0	0	5	5
Actin-related protein 2	0	0	5	5
GTP-binding nuclear protein Ran	0	0	5	5
Casein kinase I isoform gamma-2	0	0	5	5
Cyclin-dependent kinase 3	0	0	4	4
Cyclin-dependent kinase 6	0	0	5	5
Cyclin-dependent-like kinase 5	0	0	5	5
Cyclin-dependent kinase 16	0	0	5	5
Cyclin-dependent kinase 17	0	0	5	5
ATP-dependent 6-phosphofructokinase, platelet type	0	0	5	5
Dual specificity mitogen-activated protein kinase kinase 1	0	1	5	6
DNA topoisomerase 2-beta	0	0	5	5
Protein kinase C theta type	0	0	5	5
Activin receptor type-1	0	0	5	5
Macrophage-stimulating protein receptor	0	0	5	5
Focal adhesion kinase 1	0	1	5	6
Protein kinase C delta type	0	0	5	5
Tyrosine-protein kinase BTK	0	2	6	8
Activated CDC42 kinase 1	0	0	5	5
Epithelial discoidin domain-containing receptor 1	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	5	5
Serine/threonine-protein kinase 4	0	0	5	5
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	5	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	5	5
Mitogen-activated protein kinase 7	0	0	5	5
Serine/threonine-protein kinase PAK 2	0	0	5	5
Serine/threonine-protein kinase 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 1	0	0	5	5
Integrin-linked protein kinase	0	0	5	5
Rho-associated protein kinase 1	0	0	5	5
Non-receptor tyrosine-protein kinase TNK1	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	5	5
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	5	5
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	5	5
Activin receptor type-2B	0	0	5	5
Bone morphogenetic protein receptor type-2	0	0	5	5
Protein-tyrosine kinase 6	0	1	5	6
cGMP-dependent protein kinase 1	0	0	5	5
Cyclin-dependent kinase 13	0	0	5	5
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	5	5
Protein-tyrosine kinase 2-beta	0	0	5	5
Sodium channel protein type 5 subunit alpha	0	3	0	3
Maternal embryonic leucine zipper kinase	0	0	5	5
Structural maintenance of chromosomes protein 1A	0	0	5	5
Chromodomain-helicase-DNA-binding protein 4	0	0	5	5
Peroxisomal acyl-coenzyme A oxidase 1	0	0	4	4
Ephrin type-A receptor 7	0	0	4	4
Delta(24)-sterol reductase	0	0	5	5
Ribosomal protein S6 kinase alpha-1	0	2	5	7
Dual specificity testis-specific protein kinase 1	0	0	4	4
Myosin light chain kinase, smooth muscle	0	0	5	5
Mitogen-activated protein kinase 11	0	0	5	5
Serine/threonine-protein kinase STK11	0	0	5	5
Serine/threonine-protein kinase N1	0	0	5	5
Serine/threonine-protein kinase N2	0	0	5	5
Mitogen-activated protein kinase 14	0	0	5	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	5	5
Mitogen-activated protein kinase kinase kinase 11	0	0	5	5
Discoidin domain-containing receptor 2	0	0	5	5
AP2-associated protein kinase 1	0	1	5	6
Myosin light chain kinase 3	0	0	5	5
Putative heat shock protein HSP 90-beta 2	0	0	5	5
Serine/threonine-protein kinase MRCK alpha	0	0	5	5
Serine/threonine-protein kinase MRCK gamma	0	0	5	5
Acyl-CoA dehydrogenase family member 10	0	0	4	4
Serine/threonine-protein kinase N3	0	0	4	4
Serine/threonine-protein kinase ULK3	0	0	5	5
Uncharacterized protein FLJ45252	0	0	5	5
Acyl-CoA dehydrogenase family member 11	0	0	5	5
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	5	5
Serine/threonine-protein kinase MARK2	0	0	5	5
ATP-dependent RNA helicase DHX30	0	0	5	5
Serine/threonine-protein kinase TAO1	0	0	5	5
STE20-related kinase adapter protein alpha	0	0	5	5
Myosin-14	0	0	5	5
AarF domain-containing protein kinase 1	0	0	5	5
ATP-dependent RNA helicase DDX42	0	0	4	4
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	5	5
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Regulatory-associated protein of mTOR	0	2	0	2
Atypical kinase COQ8A, mitochondrial	0	0	5	5
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	5	5
Mitogen-activated protein kinase 15	0	0	5	5
Serine/threonine-protein kinase Nek9	0	0	5	5
Serine/threonine-protein kinase Nek7	0	0	3	3
ATP-dependent RNA helicase DDX1	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	5	5
MAP/microtubule affinity-regulating kinase 4	0	0	5	5
Serine/threonine-protein kinase Nek1	0	0	5	5
PAS domain-containing serine/threonine-protein kinase	0	0	5	5
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	5	5
EKC/KEOPS complex subunit TP53RK	0	0	5	5
Dual specificity testis-specific protein kinase 2	0	0	3	3
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	5	5
Mitogen-activated protein kinase kinase kinase 5	0	0	5	5
Mitogen-activated protein kinase kinase kinase 3	0	0	5	5
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	5	5
Target of rapamycin complex subunit LST8	0	2	0	2
Nucleolar GTP-binding protein 1	0	0	5	5
Serine/threonine-protein kinase D2	0	0	5	5
NUAK family SNF1-like kinase 2	0	0	4	4
RNA cytidine acetyltransferase	0	0	5	5
Serine/threonine-protein kinase SIK2	0	0	5	5
STE20-like serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase TAO3	0	0	5	5
dCTP pyrophosphatase 1	0	0	5	5
Dual specificity protein kinase CLK4	0	0	5	5
Casein kinase I isoform gamma-1	0	0	5	5
Phenylalanine--tRNA ligase beta subunit	0	0	5	5
BMP-2-inducible protein kinase	0	0	5	5
Obg-like ATPase 1	0	0	5	5
Midasin	0	0	5	5
Interleukin-1 receptor-associated kinase 4	0	0	5	5
Mitogen-activated protein kinase kinase kinase 20	0	0	5	5
Cyclin-dependent kinase 12	0	0	5	5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	4	4
Serine/threonine-protein kinase 26	0	0	5	5
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	5	5
Serine/threonine-protein kinase NLK	0	0	5	5
5'-AMP-activated protein kinase subunit gamma-2	0	0	5	6
Serine/threonine-protein kinase TBK1	0	1	5	6
Septin-9	0	0	5	5
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
Ribosomal protein S6 kinase alpha-6	0	0	5	5
TRAF2 and NCK-interacting protein kinase	0	0	5	5
Serine/threonine-protein kinase TAO2	0	0	5	5
Long-chain-fatty-acid--CoA ligase 5	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	0	5	5
Serine/threonine-protein kinase SIK3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 2	0	0	5	5
Thyroid hormone receptor-associated protein 3	0	0	5	5
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	5	5
Receptor-interacting serine/threonine-protein kinase 3	0	0	5	5
Serine/threonine-protein kinase MRCK beta	0	0	5	5
Interleukin-1 receptor-associated kinase 3	0	0	5	5
Casein kinase I isoform gamma-3	0	0	5	5
Mitogen-activated protein kinase kinase kinase 4	0	0	5	5
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
ATP-dependent translocase ABCB1	0	6	1	9
D(2) dopamine receptor	0	2	1	3
Amine oxidase [flavin-containing] A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Delta-type opioid receptor	0	2	0	2
Delta-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	4	1	5
Kappa-type opioid receptor	0	2	0	2
Histamine H1 receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	5	1	6
Mu-type opioid receptor	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
endonuclease IV	1	0	0	1
acetylcholinesterase	1	0	0	1
glp-1 receptor, partial	2	0	0	2
Skn7p	0	0	0	1
peripheral myelin protein 22 isoform 1	2	0	0	2
hemoglobin subunit beta	1	0	0	1
huntingtin isoform 2	2	0	0	2
muscleblind-like protein 1 isoform 1	3	0	0	3
Solute carrier family 22 member 8	0	0	0	1
Thymidylate synthase	0	3	0	3
Aromatase	0	2	0	2
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Neutral amino acid transporter A	0	2	0	2
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	2	0	2
Proton-coupled amino acid transporter 1	0	2	0	2
Amino acid transporter	0	2	0	2
transcriptional regulator ERG isoform 3	2	0	0	2
Acid-sensing ion channel 3	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	2
Prostaglandin G/H synthase 1	0	2	0	3
Prostaglandin G/H synthase 2	0	2	0	3
Dihydrofolate reductase	0	3	0	4
Fatty acid-binding protein, liver	0	1	0	1
Albumin	0	3	3	6
Albumin	0	1	0	1
Albumin	0	0	1	1
Cholinesterase	0	1	0	1
Fatty acid-binding protein, intestinal	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	4
UDP-glucuronosyltransferase 2B7	0	1	0	2
Prostaglandin G/H synthase 1	0	2	0	2
Adenosine receptor A1	0	2	0	2
Caspase-1	0	1	0	2
Adenosine receptor A2a	0	2	0	2
Substance-P receptor	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	3
UDP-glucuronosyltransferase 1A3	0	0	0	1
Aldo-keto reductase family 1 member C3	0	3	0	3
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Acid-sensing ion channel 1	0	1	0	1
Prostaglandin G/H synthase 2	0	5	0	5
Fatty-acid amide hydrolase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	3
Solute carrier family 22 member 6	0	3	0	4
Prostaglandin G/H synthase 1	0	2	0	3
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 8	0	3	0	5
Solute carrier family 22 member 6	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
SMAD family member 2	2	0	0	2
SMAD family member 3	2	0	0	2
glucocerebrosidase	1	0	0	1
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
cytochrome P450 2D6 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
ras-related protein Rab-9A	2	0	0	2
DNA polymerase iota isoform a (long)	3	0	0	3
neuropeptide S receptor isoform A	1	0	0	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Procathepsin L	0	1	0	1
Interleukin-8	0	1	0	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member B1	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Sodium-dependent dopamine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Thromboxane-A synthase	0	1	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	3	3
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Spike glycoprotein	4	0	0	4
Prostaglandin D2 receptor	0	2	0	2
Solute carrier organic anion transporter family member 1A3	0	1	0	3
Lactoylglutathione lyase	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Uracil nucleotide/cysteinyl leukotriene receptor	0	1	0	1
Solute carrier family 22 member 7	0	0	0	2
Sigma intracellular receptor 2	0	2	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	4	0	5
Cytosolic phospholipase A2 gamma	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Solute carrier organic anion transporter family member 1B1	0	5	0	6
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
acid sphingomyelinase	1	0	0	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
alpha-galactosidase	1	0	0	1
Thymidylate synthase	0	1	0	1
Bloom syndrome protein isoform 1	2	0	0	2
cellular tumor antigen p53 isoform a	2	0	0	2
polyunsaturated fatty acid lipoxygenase ALOX12	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
DNA polymerase beta	1	0	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
DNA polymerase eta isoform 1	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
histone acetyltransferase KAT2A isoform 1	3	0	0	3
caspase-1 isoform alpha precursor	1	0	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	2	0	2
Integrin beta-3	1	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Integrin alpha-IIb	1	0	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	2
Protein-arginine deiminase type-4	0	2	0	2
Nrf2	1	0	0	1
Microphthalmia-associated transcription factor	0	0	0	1
hypothetical protein, conserved	1	0	0	1
cytochrome P450 2D6	2	0	0	2
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	1	0	1
caspase recruitment domain family, member 15	0	1	0	1
glucose-6-phosphate 1-dehydrogenase isoform b	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
histone deacetylase 9 isoform 3	1	0	0	1
receptor-interacting serine/threonine-protein kinase 2 isoform 1	0	1	0	1
serine/threonine-protein kinase PLK1	2	0	0	2
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
Beta lactamase (plasmid)	0	1	0	1
Genome polyprotein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Tubulin alpha-1A chain	0	0	1	2
Tubulin beta chain	0	0	1	1
Tubulin beta-4A chain	0	1	1	3
Receptor tyrosine-protein kinase erbB-2	0	2	2	4
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
60 kDa chaperonin	0	1	0	1
Tubulin alpha-3C chain	0	1	1	3
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Substance-K receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	1	0	1
Cholecystokinin receptor type A	0	3	1	4
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	3	4
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Thiosulfate sulfurtransferase	0	1	0	1
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
60 kDa chaperonin	0	1	0	1
Tubulin beta-2B chain	0	0	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
10 kDa chaperonin	0	1	0	1
Similar to alpha-tubulin isoform 1	0	0	1	3
Similar to alpha-tubulin isoform 1	0	0	0	2
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
tyrosine-protein kinase Yes	2	0	0	2
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Putative nucleoside diphosphate kinase	0	0	1	1
Tyrosine-protein kinase JAK2	0	2	3	5
Macrophage colony-stimulating factor 1 receptor	0	2	1	3
Cytochrome P450 2C8	0	2	0	3
Receptor tyrosine-protein kinase erbB-3	0	1	1	2
Nucleoside diphosphate kinase B	0	0	1	1
G1/S-specific cyclin-E1	0	1	0	1
Tyrosine-protein kinase TXK	0	1	2	3
Tyrosine-protein kinase Blk	0	1	2	3
Cytoplasmic tyrosine-protein kinase BMX	0	2	2	4
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Tyrosine-protein kinase JAK3	0	1	2	3
Tyrosine-protein kinase ITK/TSK	0	1	2	3
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	1	2	3
MAP kinase-activated protein kinase 3	0	0	2	2
Rab-like protein 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	4	4
Misshapen-like kinase 1	0	0	4	4
Nuclear receptor subfamily 4 group A member 3	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	3	3
Peroxiredoxin-like 2A	0	1	0	1
Platelet glycoprotein VI	0	1	0	1
Serine/threonine-protein kinase PAK 6	0	1	3	4
Serine/threonine-protein kinase ICK	0	0	4	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	4	4
Serine/threonine-protein kinase 24	0	0	4	4
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Glutamate 5-kinase	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Beta-1 adrenergic receptor	0	1	1	3
D(1A) dopamine receptor	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Beta-2 adrenergic receptor	0	2	1	3
Muscarinic acetylcholine receptor M2	0	2	1	3
Beta-1 adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1A	0	1	0	1
Alpha-2A adrenergic receptor	0	1	2	4
Beta-2 adrenergic receptor	0	2	0	3
Muscarinic acetylcholine receptor M1	0	1	1	2
Beta-3 adrenergic receptor	0	2	1	3
Alpha-2B adrenergic receptor	0	0	1	2
Beta-1 adrenergic receptor	0	2	1	4
Alpha-2C adrenergic receptor	0	1	2	4
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	1	4
Alpha-2B adrenergic receptor	0	0	1	1
Muscarinic acetylcholine receptor M3	0	1	1	2
D(1A) dopamine receptor	0	1	1	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	0	1	1
Alpha-1D adrenergic receptor	0	2	1	3
Alpha-1D adrenergic receptor	0	0	1	2
Endothelin-1 receptor	0	1	1	2
Beta-3 adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1B	0	2	1	3
5-hydroxytryptamine receptor 2A	0	2	1	3
5-hydroxytryptamine receptor 2C	0	2	1	3
5-hydroxytryptamine receptor 1B	0	2	0	2
Neuromedin-K receptor	0	0	1	1
Type-1 angiotensin II receptor	0	1	1	2
5-hydroxytryptamine receptor 7	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	2	4
Alpha-1B adrenergic receptor	0	0	1	2
Vasopressin V1a receptor	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	1	3
5-hydroxytryptamine receptor 6	0	2	1	3
5-hydroxytryptamine receptor 7	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Sodium/bile acid cotransporter	0	1	0	1
Beta-2 adrenergic receptor	0	1	1	3
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
cytochrome P450 2C19 precursor	1	0	0	1
NADH-cytochrome b5 reductase 3	0	1	0	1
Myeloperoxidase	0	1	0	1
Thyroid peroxidase	0	1	0	1
Taste receptor type 2 member 38	0	0	1	2
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	1	1	3
Xanthine dehydrogenase/oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Cyclin-dependent kinase-like 5	0	0	3	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Serine/threonine-protein kinase receptor R3	0	0	3	3
Alpha-synuclein	1	1	0	2
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Protein kinase C zeta type	0	0	3	3
Cyclin-dependent kinase 18	0	0	3	3
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	3	3
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Isoleucine--tRNA ligase, mitochondrial	0	0	3	3
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
Membrane-associated progesterone receptor component 1	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	1	2
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
NUAK family SNF1-like kinase 1	0	1	1	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	1	1	2
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	1	1	2
Mast/stem cell growth factor receptor Kit	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	0	1
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	3	1	4
Myosin light chain kinase, smooth muscle	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Platelet-derived growth factor receptor alpha	0	2	1	3
Translocator protein	0	1	0	1
Vascular endothelial growth factor receptor 1	0	2	1	3
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Beta-adrenergic receptor kinase 1	0	1	0	1
Fibroblast growth factor receptor 2	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
Protein kinase C eta type	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	0	1
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	1	1	2
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
G protein-coupled receptor kinase 5	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	2	1	3
Vascular endothelial growth factor receptor 2	0	3	1	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	1	2
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
Cyclin-dependent kinase 8	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Protein delta homolog 1	0	1	1	2
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Protein kinase C epsilon type	0	0	1	1
Angiopoietin-1 receptor	0	1	1	2
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Serine/threonine-protein kinase ATR	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Cyclin-dependent kinase 10	0	0	2	2
Serine/threonine-protein kinase D1	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
NAD-dependent protein deacetylase sirtuin-2	0	1	0	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	1	1	2
Bromodomain-containing protein 9	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Bromodomain-containing protein 7	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	1	1	2
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	1	1	2
eIF-2-alpha kinase GCN2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	1	1	2
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Replicase polyprotein 1ab	0	1	0	1
Replicase polyprotein 1ab	0	1	0	1
90-kda heat shock protein beta HSP90 beta, partial	0	1	0	1
estrogen receptor beta isoform 1	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	1	0	1
tyrosine-protein phosphatase non-receptor type 7 isoform 2	0	1	0	1
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
Tetracycline resistance protein, class B	0	0	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Neutrophil collagenase	0	2	0	2
Collagenase 3	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Integrase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Chain X, Thyroid hormone receptor beta-1	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Rap guanine nucleotide exchange factor 3	1	0	0	1
Transthyretin	0	1	0	2
Thyroid hormone receptor alpha	0	0	1	1
Thyroid hormone receptor beta	0	0	1	1
Proliferating cell nuclear antigen	0	1	0	1
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Butyrophilin subfamily 3 member A1	0	0	1	2
Farnesyl diphosphate synthase	0	1	0	1
Matrix metalloproteinase-14	0	1	0	1
Geranylgeranyl pyrophosphate synthase	0	2	0	2
H	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

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