| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| Luciferase | 3 | 0 | 0 | 3 |
| glp-1 receptor, partial | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| ATAD5 protein, partial | 2 | 0 | 0 | 2 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| GLI family zinc finger 3 | 6 | 0 | 0 | 6 |
| AR protein | 6 | 0 | 0 | 6 |
| caspase 7, apoptosis-related cysteine protease | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
| progesterone receptor | 4 | 0 | 0 | 4 |
| glucocorticoid receptor [Homo sapiens] | 4 | 0 | 0 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
| pregnane X nuclear receptor | 6 | 0 | 0 | 6 |
| estrogen nuclear receptor alpha | 8 | 0 | 0 | 8 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 3 | 0 | 0 | 3 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 3 | 0 | 0 | 3 |
| caspase-3 | 3 | 0 | 0 | 3 |
| IDH1 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 4 | 0 | 0 | 4 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| Histone H2A.x | 4 | 0 | 0 | 4 |
| cellular tumor antigen p53 isoform a | 4 | 0 | 0 | 4 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| histone deacetylase 9 isoform 3 | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 3 | 0 | 0 | 3 |
| mitogen-activated protein kinase 1 | 3 | 0 | 0 | 3 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 5 | 0 | 0 | 5 |
| Vif | 0 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 4 | 0 | 0 | 4 |
| survival motor neuron protein isoform d | 3 | 0 | 0 | 3 |
| muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 4 | 0 | 0 | 4 |
| neuropeptide S receptor isoform A | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 5 | 0 | 5 |
| Multidrug resistance-associated protein 4 | 0 | 5 | 0 | 5 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Interferon beta | 3 | 0 | 0 | 3 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| Integrin beta-3 | 3 | 0 | 0 | 3 |
| Integrin alpha-IIb | 3 | 0 | 0 | 3 |
| Methionine aminopeptidase | 0 | 1 | 0 | 1 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Fatty-acid amide hydrolase 1 | 1 | 1 | 0 | 2 |
| Inositol monophosphatase 1 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 5 | 0 | 5 |
| ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Chain A, Cruzipain | 2 | 0 | 0 | 2 |
| aldehyde dehydrogenase 1 family, member A1 | 5 | 0 | 0 | 5 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 3 | 1 | 0 | 4 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| DNA gyrase subunit B | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 2 | 0 | 2 |
| DNA gyrase subunit B | 0 | 1 | 0 | 2 |
| DNA gyrase subunit A | 0 | 1 | 0 | 3 |
| DNA gyrase subunit B | 0 | 1 | 0 | 3 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 1 |
| DNA topoisomerase 4 subunit B | 0 | 1 | 0 | 2 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| DNA topoisomerase 2-alpha | 0 | 1 | 0 | 4 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 3 | 1 | 0 | 4 |
| DNA gyrase subunit A | 0 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 3 | 1 | 0 | 4 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Multidrug resistance protein MdtK | 0 | 0 | 1 | 1 |
| Histamine H2 receptor | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 3 | 1 | 0 | 4 |
| DNA gyrase subunit B | 0 | 1 | 0 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] | 0 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 3 | 0 | 4 |
| DNA topoisomerase 4 subunit A | 0 | 1 | 0 | 1 |
| DNA topoisomerase 4 subunit B | 0 | 1 | 0 | 1 |
| Integrase | 0 | 1 | 0 | 1 |
| GABA theta subunit | 3 | 1 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit epsilon | 3 | 1 | 0 | 4 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 4 | 0 | 0 | 4 |
| beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa] | 1 | 0 | 0 | 1 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| Microtubule-associated protein tau | 3 | 0 | 0 | 4 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| alpha synuclein, partial | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 4 | 0 | 0 | 4 |
| hypothetical protein, conserved | 2 | 0 | 0 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 3 | 0 | 0 | 3 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| luciferase | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 3 | 0 | 0 | 3 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
| tumor necrosis factor | 1 | 0 | 0 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 2 | 0 | 0 | 2 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 3A4 isoform 1 | 3 | 0 | 0 | 3 |
| lethal factor (plasmid) | 4 | 0 | 0 | 4 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| 60 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Androgen receptor | 0 | 2 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 1 | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Adenosine receptor A2a | 0 | 2 | 0 | 2 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, kainate 2 | 1 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 3 | 1 | 0 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Nuclear receptor ROR-gamma | 2 | 0 | 0 | 2 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| 10 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Disintegrin and metalloproteinase domain-containing protein 17 | 1 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 4 | 1 | 0 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Leukotriene B4 receptor 1 | 1 | 0 | 0 | 1 |
| Thiosulfate sulfurtransferase | 0 | 1 | 0 | 1 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, kainate 5 | 1 | 0 | 0 | 1 |
| 10 kDa chaperonin | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Leukotriene B4 receptor 2 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| PPM1D protein | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| pyruvate kinase PKM isoform a | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Endothelin receptor type B | 1 | 0 | 0 | 1 |
| Endothelin-1 receptor | 1 | 1 | 0 | 2 |
| Signal transducer and activator of transcription 3 | 0 | 1 | 0 | 1 |
| Pyruvate-flavodoxin oxidoreductase | 0 | 1 | 0 | 1 |
| Anoctamin-1 | 0 | 1 | 0 | 1 |
| Glucocorticoid receptor | 0 | 0 | 0 | 1 |
| Chain A, MALTOPORIN | 0 | 0 | 1 | 1 |
| Chain B, MALTOPORIN | 0 | 0 | 1 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 1 | 2 |
| Carbonic anhydrase 9 | 0 | 1 | 1 | 2 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| exodeoxyribonuclease V subunit RecD | 0 | 1 | 0 | 1 |
| exodeoxyribonuclease V subunit RecB | 0 | 1 | 0 | 1 |
| exodeoxyribonuclease V subunit RecC | 0 | 1 | 0 | 1 |
| ATP-dependent 6-phosphofructokinase | 0 | 1 | 0 | 1 |
| Dihydropteroate synthase | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 3 | 0 | 4 |
| Protease | 0 | 1 | 1 | 2 |
| Protein-arginine deiminase type-4 | 0 | 2 | 0 | 2 |
| Chain A, Dihydrofolate Reductase | 0 | 0 | 1 | 1 |
| Chain A, Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Chain A, dihydrofolate reductase (DHFR) | 0 | 1 | 0 | 1 |
| Chain A, Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Chain A, Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 2 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase type 1 | 0 | 1 | 0 | 2 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Thymidylate synthase | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| NH(3)-dependent NAD(+) synthetase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Thymidylate synthase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase type 1 from Tn4003 | 0 | 1 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Dipeptidyl peptidase 4 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| Metabotropic glutamate receptor 5 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
| Bifunctional dihydrofolate reductase-thymidylate synthase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Trace amine-associated receptor 5 | 0 | 0 | 1 | 1 |
| Dihydrofolate reductase | 0 | 2 | 0 | 2 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 2 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Urease subunit alpha | 0 | 1 | 0 | 1 |
| Urease subunit beta | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |