Page last updated: 2024-09-28

Crigler Najjar Syndrome

A familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. It is characterized by icterus and brain damage caused by a glucuronyl transferase deficiency in the liver and faulty bilirubin conjugation.

Synonyms(7)

Synonym
Familial Nonhemolytic Unconjugated Hyperbilirubinemia
Crigler-Najjar Syndrome
Crigler-Najar Syndrome
Hereditary Unconjugated Hyperbilirubinemia
Crigler-Najjar Syndrome, Type I
Crigler Najjar Syndrome
Crigler Najjar Syndrome, Type 1

Research

Studies (232)

TimeframeStudies, This Condition (%)All Conditions %
pre-199052 (22.41)23.3326
1990's65 (28.02)12.5806
2000's58 (25.00)18.1394
2010's47 (20.26)28.8240
2020's10 (4.31)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbamates0medium11
carbon monoxide0low10
choline0low10
creatine0low10
glycine0low20
melatonin0low10
nitrous oxide0low10
4-nitrophenol0low30
urea0low30
phenytoin0low20
azathioprine0low10
baclofen0low10
benzo(a)pyrene0low10
clofibrate0low10
diflunisal0low10
ethosuximide0low10
etodolac0low10
fenofibrate0low10
fentanyl0low10
flumazenil0low10
glutethimide0low10
isoflurane0low20
midazolam0low10
apnea0low10
o(6)-benzylguanine0low10
ofloxacin0low10
phenobarbital0medium371
propofol0low20
propranolol0low10
sulfobromophthalein0low30
thyroxine0low10
androsterone0low10
aspartic acid0low20
glutamine0low10
uridine0low10
uridine diphosphate0low20
tyrosine0low20
leucine0low10
phenylalanine0low20
arginine0low30
methylprednisolone0low20
1-naphthol0low10
pyrroles0low20
2-naphthol0low10
chenodeoxycholic acid0low10
glycylglycine0low10
uridine diphosphate glucuronic acid0low10
technetium0low10
camptothecin0low30
zinc sulfate0low10
calcium phosphate, dibasic, anhydrous0medium11
calcium phosphate, monobasic, anhydrous0medium11
tricalcium phosphate0medium21
urobilinogen0low10
ursodeoxycholic acid0low10
azides0low10
zidovudine0low10
irinotecan0low30
6-sulfatoxymelatonin0low10
glucuronic acid0low10
ezogabine0medium11
levofloxacin0low10
ezetimibe0low20
calcium pyrophosphate0medium11
atropine0low10
retinol0low10
tacrolimus0low10
mycophenolic acid0low10
obeticholic acid0low10
t09013170low10
buprenorphine0low10
orlistat0medium21
bilirubin0medium1854
retinol palmitate0low10
hymecromone0low20
bilirubin diglucuronide0low20
nalorphine0low10
morphine0low10
naltrexone0low10
pregnanediol0low10
hypericum0low10
technetium tc 99m disofenin0low20
scopolamine hydrobromide0low10
tin mesoporphyrin0low30
oligonucleotides0low20
sodium salicylate0low10
triiodothyronine, reverse0low10
heme0low30
nitrophenols0low30
guanine0low10
guanosine0low10
concanavalin a0low10

Protein Targets (829)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Luciferase100010
RAR-related orphan receptor gamma180018
GLI family zinc finger 3180018
AR protein280028
estrogen receptor 2 (ER beta)110011
nuclear receptor subfamily 1, group I, member 3190019
progesterone receptor130013
retinoic acid nuclear receptor alpha variant 1180018
estrogen-related nuclear receptor alpha240024
farnesoid X nuclear receptor110011
pregnane X nuclear receptor200020
estrogen nuclear receptor alpha290029
peroxisome proliferator activated receptor gamma130013
aryl hydrocarbon receptor9009
Histone H2A.x8008
nuclear factor erythroid 2-related factor 2 isoform 1210021
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
DNA repair and recombination protein RadA0022
Voltage-dependent calcium channel gamma-2 subunit9009
Cytochrome P450 1A20505
Cytochrome P450 2A60202
Polyunsaturated fatty acid 5-lipoxygenase0101
Glutamate receptor 291010
Cytochrome P450 2A50202
UDP-glucuronosyltransferase 1A1 04110
MAP kinase-activated protein kinase 20101
retinoid X nuclear receptor alpha150015
peroxisome proliferator-activated receptor delta120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a130013
v-jun sarcoma virus 17 oncogene homolog (avian)8008
thyroid hormone receptor beta isoform 2110011
Cellular tumor antigen p53150015
Sulfotransferase 1A1 0001
Sulfotransferase 1E10001
Sulfotransferase 1A10001
Sulfotransferase 2A10001
Chain A, Sulfotransferase 1A10101
Chain A, Sulfotransferase 1A10101
acetylcholinesterase120012
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a8008
histone deacetylase 9 isoform 31001
Endolysin0011
UDP-glucuronosyltransferase 1A40115
Chain A, retinol dehydratase0101
TDP1 protein260026
histone acetyltransferase KAT2A isoform 18008
Gamma-aminobutyric acid receptor subunit pi118221
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
Glucose-6-phosphate 1-dehydrogenase0101
Androgen receptor0303
Gamma-aminobutyric acid receptor subunit beta-1118221
Gamma-aminobutyric acid receptor subunit delta118221
Gamma-aminobutyric acid receptor subunit gamma-2118322
Gamma-aminobutyric acid receptor subunit alpha-5118221
Gamma-aminobutyric acid receptor subunit alpha-3118221
Gamma-aminobutyric acid receptor subunit gamma-1118221
Gamma-aminobutyric acid receptor subunit alpha-2118221
Gamma-aminobutyric acid receptor subunit alpha-4118221
Gamma-aminobutyric acid receptor subunit gamma-3118221
Gamma-aminobutyric acid receptor subunit alpha-6118221
Solute carrier organic anion transporter family member 1A10101
Gamma-aminobutyric acid receptor subunit alpha-1118322
Gamma-aminobutyric acid receptor subunit beta-3118221
Gamma-aminobutyric acid receptor subunit beta-2118322
TAR DNA-binding protein 436006
G-protein coupled bile acid receptor 10044
GABA theta subunit118221
Gamma-aminobutyric acid receptor subunit epsilon118221
thioredoxin reductase190019
ATAD5 protein, partial7007
Microtubule-associated protein tau9009
arylsulfatase A110011
euchromatic histone-lysine N-methyltransferase 2240024
Bloom syndrome protein isoform 1130013
D(1A) dopamine receptor4004
lamin isoform A-delta10160016
neuropeptide S receptor isoform A4004
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase110011
NFKB1 protein, partial5005
GLS protein7007
thyroid stimulating hormone receptor8008
alpha-galactosidase3003
cytochrome P450 2C19 precursor6006
chromobox protein homolog 1140014
flap endonuclease 16006
DNA polymerase iota isoform a (long)110011
muscarinic acetylcholine receptor M19009
lethal factor (plasmid)5005
Cytochrome P450 3A407210
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase120012
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, Ferritin light chain100010
aldehyde dehydrogenase 1 family, member A1160016
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10509
Carbonic anhydrase 20509
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0316
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0316
Glutamate receptor ionotropic, NMDA 2B0316
Glutamate receptor ionotropic, NMDA 2C0316
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0004
Glutamate receptor ionotropic, NMDA 2D0316
Glutamate receptor ionotropic, NMDA 3B0316
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0316
Chain A, 2-oxoglutarate Oxygenase100010
glucocorticoid receptor [Homo sapiens]150015
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0708
ATP-binding cassette sub-family C member 3017017
Multidrug resistance-associated protein 4017017
5-hydroxytryptamine receptor 408210
Bile salt export pump024024
Muscarinic acetylcholine receptor M20429
Muscarinic acetylcholine receptor M40619
Muscarinic acetylcholine receptor M105310
Muscarinic acetylcholine receptor M30439
Muscarinic acetylcholine receptor M40439
Muscarinic acetylcholine receptor M50439
Muscarinic acetylcholine receptor M50316
Muscarinic acetylcholine receptor M205412
Muscarinic acetylcholine receptor M105210
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30428
Alpha-1D adrenergic receptor0214
5-hydroxytryptamine receptor 2C0819
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor4005
5-hydroxytryptamine receptor 70303
Reverse transcriptase/RNaseH 0127
Muscarinic acetylcholine receptor0112
Canalicular multispecific organic anion transporter 1017017
interleukin 83003
SMAD family member 28008
Fumarate hydratase4004
SMAD family member 38008
thioredoxin glutathione reductase3003
EWS/FLI fusion protein150015
G150015
polyprotein4004
P531001
IDH13003
thyroid stimulating hormone receptor4004
activating transcription factor 69009
peripheral myelin protein 22 isoform 19009
hemoglobin subunit beta2002
cellular tumor antigen p53 isoform a2002
heat shock protein beta-18008
geminin200020
peripheral myelin protein 228008
survival motor neuron protein isoform d5005
cytochrome P450 3A4 isoform 1110011
M-phase phosphoprotein 85005
muscleblind-like protein 1 isoform 14004
Bile salt export pump0404
Interferon beta170017
HLA class I histocompatibility antigen, B alpha chain 150015
Nuclear receptor ROR-gamma3216
Inositol hexakisphosphate kinase 1150015
ATPase family AAA domain-containing protein 54004
Ataxin-25005
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial150015
Carbonic anhydrase 40103
Carbonic anhydrase0103
Carbonic anhydrase 150103
regulator of G-protein signaling 46006
67.9K protein6006
Gamma-aminobutyric acid type B receptor subunit 20213
Gamma-aminobutyric acid type B receptor subunit 20202
Gamma-aminobutyric acid type B receptor subunit 10213
Gamma-aminobutyric acid type B receptor subunit 10101
Chain A, JmjC domain-containing histone demethylation protein 3A3003
acid sphingomyelinase1001
glp-1 receptor, partial3003
hypoxia-inducible factor 1 alpha subunit4004
Smad32002
apical membrane antigen 1, AMA12002
caspase 7, apoptosis-related cysteine protease6006
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
caspase-36006
nuclear factor erythroid 2-related factor 2 isoform 27007
importin subunit beta-1 isoform 12002
snurportin-12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
GTP-binding nuclear protein Ran isoform 11001
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Receptor tyrosine-protein kinase erbB-20101
Tyrosine-protein kinase Fyn0101
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0606
Aryl hydrocarbon receptor0011
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, Cruzipain3003
USP1 protein, partial100010
vitamin D3 receptor isoform VDRA3003
DNA polymerase kappa isoform 16006
caspase-1 isoform alpha precursor2002
Caspase-72002
Inositol monophosphatase 14004
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10305
Kappa-type opioid receptor0809
Kappa-type opioid receptor09316
DNA topoisomerase 0101
15-lipoxygenase, partial4004
PPM1D protein3003
Thrombopoietin1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
glucocerebrosidase2002
putative alpha-glucosidase1001
lysosomal alpha-glucosidase preproprotein2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 19009
huntingtin isoform 21001
ras-related protein Rab-9A2002
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
serine/threonine-protein kinase mTOR isoform 13003
nuclear receptor ROR-gamma isoform 1110011
relaxin receptor 1 isoform 11001
Telomerase reverse transcriptase0101
Serine/threonine-protein kinase Chk10011
Histone deacetylase 30101
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0001
DNA ligase0101
Integrin beta-31001
Integrin alpha-IIb1001
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 10117
DNA topoisomerase 2-alpha0101
Type-2 restriction enzyme BamHI0101
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
5-hydroxytryptamine receptor 2B0617
Type-2 restriction enzyme HindIII0101
D(1A) dopamine receptor1001
Histone deacetylase 40101
Ribonuclease pancreatic0202
DNA topoisomerase 2-beta0001
DNA topoisomerase 10102
Histone deacetylase 10101
DNA topoisomerase 10101
Integrase 0101
Histone deacetylase 70101
Histone deacetylase 20101
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
cytochrome P450 family 3 subfamily A polypeptide 4100010
Caspase-72002
caspase-32002
Alpha-2A adrenergic receptor0157
Vitamin D3 receptor0224
Alpha-2B adrenergic receptor0034
Alpha-2C adrenergic receptor0348
Retinoic acid receptor RXR-alpha0011
Guanine nucleotide-binding protein G3003
Ileal sodium/bile acid cotransporter0202
Bile acid receptor0011
Bile acid receptor0246
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20102
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-40202
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-20202
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70202
Solute carrier family 22 member 10102
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
Chain A, Beta-lactamase2002
GALC protein2002
potassium voltage-gated channel subfamily H member 2 isoform d6006
Fatty acid-binding protein, liver0224
Peroxisome proliferator-activated receptor alpha0022
Peroxisome proliferator-activated receptor gamma0156
Peroxisome proliferator-activated receptor gamma0022
Peroxisome proliferator-activated receptor alpha0123
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10304
electroneutral potassium-chloride cotransporter KCC20011
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Dihydrofolate reductase0202
Transthyretin0227
Albumin0145
High mobility group protein B10011
Disintegrin and metalloproteinase domain-containing protein 173003
Solute carrier family 22 member 60203
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase0202
Voltage-dependent T-type calcium channel subunit alpha-1I0101
cytochrome P450 2D64004
atrial natriuretic peptide receptor 1 precursor2002
Solute carrier family 22 member 60102
Prostaglandin G/H synthase 10202
Prostaglandin G/H synthase 20101
UDP-glucuronosyltransferase 2B70116
UDP-glucuronosyltransferase 1A30013
Spike glycoprotein5005
Sodium/bile acid cotransporter0303
NPC1-like intracellular cholesterol transporter 10101
NPC1-like intracellular cholesterol transporter 10101
Potassium voltage-gated channel subfamily KQT member 30013
Potassium voltage-gated channel subfamily KQT member 20013
UDP-glucuronosyltransferase 1A90013
UDP-glucuronosyltransferase 2B110011
UDP-glucuronosyltransferase 2B170011
Potassium voltage-gated channel subfamily KQT member 20011
Potassium voltage-gated channel subfamily KQT member 3 0011
Sodium channel protein type 2 subunit alpha0112
UDP-glucuronosyltransferase 2B40011
UDP-glucuronosyltransferase 2A10011
UDP-glucuronosyltransferase 2A20011
UDP-glucuronosyltransferase 1-60112
UDP-glucuronosyltransferase 1A50011
UDP-glucuronosyltransferase 2B10 0112
UDP-glucuronosyltransferase 2B150011
Potassium voltage-gated channel subfamily KQT member 40011
UDP-glucuronosyltransferase 2A30011
UDP-glucuronosyltransferase 2B280011
UDP-glucuronosyltransferase 1A70012
UDP-glucuronosyltransferase 1A100012
UDP-glucuronosyltransferase 1A80014
Potassium voltage-gated channel subfamily KQT member 50012
Potassium voltage-gated channel subfamily KQT member 2 0011
endonuclease IV3003
nonstructural protein 13003
bromodomain adjacent to zinc finger domain 2B2002
serine-protein kinase ATM isoform a1001
cytochrome P450 2C9 precursor4004
mitogen-activated protein kinase 12002
Fatty acid-binding protein, liver0101
Aldo-keto reductase family 1 member B10505
Adenosine receptor A30314
Fatty acid-binding protein, intestinal0112
Beta-3 adrenergic receptor0415
Alpha-1B adrenergic receptor0314
Sodium-dependent noradrenaline transporter 0404
Cruzipain0101
5-hydroxytryptamine receptor 2A0415
D(3) dopamine receptor0303
Peroxisome proliferator-activated receptor alpha0011
Alpha-1A adrenergic receptor0415
Sodium-dependent dopamine transporter 0202
Sigma non-opioid intracellular receptor 10112
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Nuclear receptor subfamily 1 group I member 20167
ATP-dependent translocase ABCB10506
D(2) dopamine receptor0213
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0202
Delta-type opioid receptor0619
Delta-type opioid receptor07311
Mu-type opioid receptor08415
Kappa-type opioid receptor06310
Histamine H1 receptor0101
Mu-type opioid receptor08516
Delta-type opioid receptor08415
Mu-type opioid receptor06211
Mu-type opioid receptor0719
Potassium voltage-gated channel subfamily H member 20808
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10505
cytochrome P450 2D6 isoform 13003
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Gamma-aminobutyric acid receptor subunit alpha-10325
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20325
5-hydroxytryptamine receptor 1A0517
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Gamma-aminobutyric acid receptor subunit beta-30325
Gamma-aminobutyric acid receptor subunit alpha-50224
Gamma-aminobutyric acid receptor subunit alpha-30224
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit epsilon0202
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit theta0202
Chain A, Glutamine Binding Protein0011
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10405
Serine racemase0101
Olfactory receptor 51E20033
Sodium- and chloride-dependent glycine transporter 20101
Angiotensin-converting enzyme 0101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10213
Glutamate receptor 40101
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
Solute carrier family 15 member 20101
Purine nucleoside phosphorylase0203
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Adenosylhomocysteinase0102
Acetylcholinesterase0202
Carbonic anhydrase 120103
Aldo-keto reductase family 1 member B10101
Nuclear factor NF-kappa-B p105 subunit0101
Genome polyprotein0101
Testosterone 17-beta-dehydrogenase 30101
Small conductance calcium-activated potassium channel protein 30101
Cholinesterase0101
Sorbitol dehydrogenase0101
Induced myeloid leukemia cell differentiation protein Mcl-10202
Carbonic anhydrase 90103
Oleandomycin glycosyltransferase0001
Chain A, Acetylcholinesterase0101
interferon gamma precursor0002
Solute carrier family 22 member 30101
Interstitial collagenase0101
Acetylcholinesterase0101
Liver carboxylesterase 10001
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10202
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Replicase polyprotein 1ab0101
CAAX prenyl protease 2 isoform 20001
streptokinase A precursor0022
Tubulin beta-4A chain0101
Tubulin beta chain0101
Tubulin alpha-3C chain0101
Tubulin alpha-1B chain0101
Tubulin alpha-4A chain0101
Tubulin beta-4B chain0101
Fatty-acid amide hydrolase 10303
DNA gyrase subunit A0203
DNA primase0101
Tubulin beta-3 chain0101
Tubulin beta-2A chain0101
Tubulin beta-8 chain0101
Tubulin alpha-3E chain0101
Tubulin alpha-1A chain0101
Tubulin alpha-1C chain0101
Tubulin beta-6 chain0101
Tubulin beta-2B chain0101
Tubulin beta-1 chain0101
ClpP1001
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Myeloperoxidase0202
Cholinesterase0101
Cytochrome P450 2C11 0101
Cytochrome P450 2D60304
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0101
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Palmitoleoyl-protein carboxylesterase NOTUM0101
Carboxylic ester hydrolase 0101
Histamine H3 receptor0101
nuclear receptor subfamily 1, group I, member 22002
Glucocorticoid receptor0213
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Nuclear receptor subfamily 1 group I member 20011
ATP-dependent translocase ABCB10202
Translocator protein0213
ATP-dependent translocase ABCB10202
Opioid receptor, delta 1b 0101
Opioid receptor homologue0101
Acyl-CoA desaturase 10101
Histidine decarboxylase0033
Proteinase-activated receptor 10112
Sodium-dependent serotonin transporter0202
Kappa-type opioid receptor0629
Nociceptin receptor0101
Mu-type opioid receptor0101
Beta-2 adrenergic receptor0315
Mas-related G-protein coupled receptor member X20011
Mu-type opioid receptor0101
Chain A, Inosine-5'-Monophosphate Dehydrogenase 20101
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Inosine-5'-monophosphate dehydrogenase 20202
Glutamate receptor 10101
Glutamate receptor 30101
Glutamate receptor 40101
Inosine-5'-monophosphate dehydrogenase 1 0202
Alpha-synuclein3104
Inosine-5'-monophosphate dehydrogenase0102
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
Nociceptin receptor0101
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
transcriptional regulator ERG isoform 32002
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
Cyclin-dependent kinase 10101
G2/mitotic-specific cyclin-B10101
G2/mitotic-specific cyclin-B0101
Methylated-DNA--protein-cysteine methyltransferase0102
Cyclin-A20101
Cyclin-dependent kinase 20101
Cyclin-A10101
Cyclin-dependent kinase 10101
G-protein coupled bile acid receptor 10011
STE240001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor5005
CAAX prenyl protease0001
Trypsin0001
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA gyrase subunit B0102
Fatty-acid amide hydrolase 10202
Rap guanine nucleotide exchange factor 36006
Phosphatidylserine lipase ABHD16A0101
Pancreatic triacylglycerol lipase0203
Lipoprotein lipase0101
Hepatic triacylglycerol lipase0101
Pancreatic triacylglycerol lipase0101
Proteasome subunit beta type-10101
Cannabinoid receptor 10202
Proteasome subunit beta type-50101
Cytochrome P450 2C190202
Cannabinoid receptor 2 0101
Fatty acid synthase0202
Proteasome subunit beta type-20101
Platelet-activating factor acetylhydrolase0101
Neutral cholesterol ester hydrolase 10101
Diacylglycerol lipase-alpha0101
Lysophosphatidylserine lipase ABHD120101
Diacylglycerol lipase-beta0101
Monoacylglycerol lipase ABHD60101
Acyl-protein thioesterase 20101
Diacylglycerol lipase-alpha0101
Endothelial lipase0101
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
Sodium channel protein type 3 subunit alpha0202
thyroid hormone receptor beta isoform a4004
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Plasma kallikrein0013
Carbonic anhydrase 30002
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Carbonic anhydrase 60002
Adenosine receptor A10002
Adenosine receptor A2a0002
Carbonic anhydrase 5A, mitochondrial0002
Carbonic anhydrase 70002
Carbonic anhydrase0002
E3 ubiquitin-protein ligase XIAP0101
SLC16A10 protein0002
Carbonic anhydrase 0002
Carbonic anhydrase0002
Carbonic anhydrase0002
Large neutral amino acids transporter small subunit 1 0101
Carbonic anhydrase 0002
Carbonic anhydrase 130001
Monocarboxylate transporter 100002
Carbonic anhydrase 130001
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
Gamma-aminobutyric acid 0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Dihydrofolate reductase 0101
Cytochrome P450 2C9 0202
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Sodium channel protein type 4 subunit alpha0102
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Polyunsaturated fatty acid lipoxygenase ALOX150101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
Beta-1 adrenergic receptor 0113
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0213
5-hydroxytryptamine receptor 1A0101
Beta-2 adrenergic receptor0203
Cytochrome P450 2C80101
Beta-1 adrenergic receptor0214
D(3) dopamine receptor0101
Alpha-2B adrenergic receptor0011
D(1A) dopamine receptor0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Alpha-2C adrenergic receptor0011
Alpha-2A adrenergic receptor0011
Alpha-1D adrenergic receptor0112
Endothelin-1 receptor0112
Beta-3 adrenergic receptor0202
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 1B0202
Adenosine receptor A2a0112
Neuromedin-K receptor0011
Type-1 angiotensin II receptor0112
Sodium-dependent serotonin transporter0202
Cholecystokinin receptor type A0112
5-hydroxytryptamine receptor 70112
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0124
Alpha-1B adrenergic receptor0012
Vasopressin V1a receptor0112
5-hydroxytryptamine receptor 60213
Cytochrome P450 2J20101
Beta-2 adrenergic receptor0101
Nuclear receptor subfamily 2 group E member 10022
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR0011
pregnane X receptor2002
Retinol-binding protein 40011
Beta-lactoglobulin0011
Amyloid-beta precursor protein0101
Hematopoietic prostaglandin D synthase0101
Chain A, Oxysterols receptor LXR-beta0101
Chain A, Oxysterols receptor LXR-beta0101
PINK11001
Parkin1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
Retinoic acid receptor RXR-alpha0134
Nuclear receptor ROR-alpha0213
Alpha-glucosidase MAL320101
Presenilin-10112
Presenilin-20112
Oxysterols receptor LXR-beta0224
Oxysterols receptor LXR-alpha0224
Oxysterols receptor LXR-beta0011
Oxysterols receptor LXR-beta0011
Gamma-secretase subunit APH-1B0112
Rap guanine nucleotide exchange factor 41001
Nicastrin0112
Nuclear receptor ROR-beta0112
Gamma-secretase subunit APH-1A0112
Gamma-secretase subunit PEN-20112
Cytochrome P450 3A50101
Serine/threonine-protein kinase mTOR0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Peptidyl-prolyl cis-trans isomerase FKBP50101
Splicing factor 3B subunit 30101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
serine/threonine-protein kinase PLK12002
DNA polymerase eta isoform 11001
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Polyphenol oxidase 20001
Tubulin--tyrosine ligase0101
Taste receptor type 2 member 140001
Urease subunit alpha0101
Urease subunit beta0101
Chain A, Cytidine Deaminase0101
Sodium/nucleoside cotransporter 10202
Sodium/nucleoside cotransporter 20202
Cytidine deaminase0101
Equilibrative nucleoside transporter 20202
Protein cereblon0202
Equilibrative nucleoside transporter 10202
Uridine-cytidine kinase 1 0001
Solute carrier family 28 member 30202
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit0101
Seminal ribonuclease0101
Ribonucleoside-diphosphate reductase large subunit0001
Ribonucleoside-diphosphate reductase subunit M20001
P2Y purinoceptor 20011
P2Y purinoceptor 10011
P2Y purinoceptor 40011
UDP-galactopyranose mutase0011
P2Y purinoceptor 60011
P2Y purinoceptor 140022
UDP-galactopyranose mutase0011
P2Y purinoceptor 60011
Ribonucleoside-diphosphate reductase subunit M2 B0001
Ubiquitin carboxyl-terminal hydrolase 20101
CDGSH iron-sulfur domain-containing protein 10202
M1-family alanyl aminopeptidase0101
pyruvate kinase PKM isoform a1001
tyrosine-protein kinase Yes1001
Ectonucleoside triphosphate diphosphohydrolase 10001
Thymidine kinase, cytosolic0203
Protein kinase C beta type0101
DNA polymerase beta0101
Thymidine kinase, cytosolic 0001
Thymidylate kinase0101
Protein kinase C epsilon type0101
Thymidine kinase 0102
Solute carrier family 22 member 70001
Protease 0112
Solute carrier family 22 member 80001
Solute carrier family 22 member 110001
Thymidine kinase0102
Solute carrier family 22 member 70001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]