Page last updated: 2024-09-28

Craniofacial Microsomia

Mandibulofacial dysostosis with congenital eyelid dermoids.

Synonyms(21)

Synonym
OAVS with Radial Defect
Microsomia Hemifacial Radial Defects
Oculoauriculovertebral Dysplasia
Goldenhar Disease
Oculoauriculovertebral Spectrum
Oculoauriculovertebral Spectrum with Radial Defect
Goldenhar Syndrome
Oculoauriculovertebral Syndrome
Goldenhar-Gorlin Syndrome
Moeschler Clarren Syndrome
Lateral Facial Dysplasia
Facioauriculovertebral Dysplasia
Hemifacial Microsomia
Otomandibular Dysostosis
Facioauriculovertebral Sequence
Hemifacial Microsomia with Radial Defects
First and Second Branchial Arch Syndrome
Oral-Mandibular-Auricular Syndrome
Craniofacial Microsomia
Goldenhar Syndrome with Ipsilateral Radial Defect
First and Second Pharyngeal Arch Syndromes

Research Excerpts

Overview

ExcerptReference
"Oculoauriculovertebral dysplasia is a developmental disorder characterized by a triad of anomalies; epibulbar dermoids with or without lipodermoids, preauricular appendages or blind preauricular fistulae, and vertebral anomalies."( Hendricks, WM; Kallor, AD, 1979)
"Goldenhar syndrome is a well-known developmental anomaly of maxillofacial skeleton and hemi-facial soft tissue, was later included to a broader classification called oculo-ariculo-vertebral spectrum."( Canter, HI; Konaş, E; Mavili, ME, 2006)
"Children with Goldenhar syndrome are known to present airway management challenges for the anesthesiologist."( Rosenblatt, WH; Sukhupragarn, W, 2008)
"Goldenhar syndrome is characterized by the typical features of craniofacial microsomia (CFM) with the addition of epibulbar dermoids and vertebral anomalies."( Bartlett, SP; Paliga, JT; Tahiri, Y; Taylor, JA; Tuin, J, 2015)

Research

Studies (63)

TimeframeStudies, This Condition (%)All Conditions %
pre-199013 (20.63)23.3326
1990's14 (22.22)12.5806
2000's9 (14.29)18.1394
2010's18 (28.57)28.8240
2020's9 (14.29)9.53
DrugIndicatedRelationship StrengthStudiesTrials
nitrous oxide0low30
aspirin0low10
bupivacaine0low10
valproic acid0low10
fluoxetine0low10
gentamicin0low10
halothane0low20
2-propanol0low10
apnea0low10
primidone0low10
propofol0low10
sevoflurane0low40
thalidomide0low10
alanine0low10
kanamycin a0low10
medroxyprogesterone acetate0low10
medroxyprogesterone0low10
glycopyrrolate0low10
cladribine0low10
titanium0low20
trolamine salicylate0low20
propiconazole0low50
fomesafen0low10
cephalosporin c0low10
atropine0low10
inositol 3-phosphate0low40
trichostatin a0low10
tretinoin0low30
cocaine0low20
mercaptopurine0low10
pica0low10
quinine0low10
misoprostol0low10
phenylephrine hydrochloride0low60
fluorapatite0low10
beta-sitosterol oleate0low20
jaw0low10
cardiovascular agents0low10
transforming growth factor beta0low10
eye0low60

Protein Targets (663)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit4004
RAR-related orphan receptor gamma120012
GLI family zinc finger 3160016
AR protein150015
aldehyde dehydrogenase 1 family, member A1100010
retinoic acid nuclear receptor alpha variant 1130013
retinoid X nuclear receptor alpha130013
estrogen nuclear receptor alpha190019
peroxisome proliferator-activated receptor delta8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x7007
thyroid hormone receptor beta isoform a6006
heat shock protein beta-14004
nuclear factor erythroid 2-related factor 2 isoform 1160016
lamin isoform A-delta109009
Voltage-dependent calcium channel gamma-2 subunit8008
Glutamate receptor 28008
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase7007
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
thioredoxin reductase6006
GALC protein3003
nuclear receptor subfamily 1, group I, member 3140014
cytochrome P450 family 3 subfamily A polypeptide 49009
glucocorticoid receptor [Homo sapiens]110011
estrogen-related nuclear receptor alpha160016
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A5005
Carbonic anhydrase0101
euchromatic histone-lysine N-methyltransferase 2140014
Bloom syndrome protein isoform 17007
geminin9009
peripheral myelin protein 225005
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 12002
Gamma-aminobutyric acid receptor subunit pi4217
ATP-binding cassette sub-family C member 3011011
Multidrug resistance-associated protein 4011011
Carbonic anhydrase0101
Solute carrier family 22 member 60202
Carbonic anhydrase 120215
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump014014
Glycogen phosphorylase, muscle form0101
Renin0202
Carbonic anhydrase 105111
Carbonic anhydrase 205110
Carbonic anhydrase 20202
Cytochrome P450 1A20213
Carbonic anhydrase 30215
Cathepsin B0101
Cytochrome P450 3A40415
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0505
Polyunsaturated fatty acid 5-lipoxygenase0202
Cytochrome P450 2C80202
Cytochrome P450 2D60516
Cytochrome P450 2A60202
Cytochrome P450 2C9 0314
5-hydroxytryptamine receptor 2A0505
Androgen receptor0707
Gamma-aminobutyric acid receptor subunit beta-14217
Translocator protein0101
Gamma-aminobutyric acid receptor subunit delta4217
Gamma-aminobutyric acid receptor subunit gamma-24217
Gamma-aminobutyric acid receptor subunit alpha-54217
Gamma-aminobutyric acid receptor subunit alpha-34217
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60202
Carbonic anhydrase 40214
Carbonic anhydrase 60214
Gamma-aminobutyric acid receptor subunit gamma-14217
Gamma-aminobutyric acid receptor subunit alpha-24217
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A10202
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-44217
Gamma-aminobutyric acid receptor subunit gamma-34217
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-64217
Adenosine receptor A2a0202
5-hydroxytryptamine receptor 2B0505
Sodium-dependent serotonin transporter0506
Delta-type opioid receptor0101
Cytochrome P450 2C190415
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Carbonic anhydrase 5A, mitochondrial0215
Carbonic anhydrase0101
Kappa-type opioid receptor0101
Carbonic anhydrase 70214
Carbonic anhydrase0101
D(1A) dopamine receptor2103
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0101
D(2) dopamine receptor0303
Gamma-aminobutyric acid receptor subunit alpha-14318
Gamma-aminobutyric acid receptor subunit beta-34217
Gamma-aminobutyric acid receptor subunit beta-24217
Cholinesterase0101
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Fatty-acid amide hydrolase 10202
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0202
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 90215
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0101
Carbonic anhydrase 30101
Carbonic anhydrase0102
Carbonic anhydrase0102
Carbonic anhydrase 0101
Sigma intracellular receptor 20202
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10303
Renin0101
Carbonic anhydrase 0101
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130214
GABA theta subunit4217
Canalicular multispecific organic anion transporter 1011011
Carbonic anhydrase 40203
Carbonic anhydrase 150102
Acidic mammalian chitinase0101
Carbonic anhydrase 130203
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon4217
Carbonic anhydrase 0101
Carbonic anhydrase 140215
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0215
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 0202
Proton-coupled amino acid transporter 10101
Adenosine deaminase0001
ATAD5 protein, partial5005
TDP1 protein130013
Microtubule-associated protein tau6006
D(1A) dopamine receptor4004
neuropeptide S receptor isoform A3003
Chain A, Phospholipase A2 isoform 30011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, 2-oxoglutarate Oxygenase5005
GTP-binding protein (rab7)0011
ras protein, partial0011
interleukin 82002
GLS protein3003
thyroid stimulating hormone receptor3003
hypothetical protein, conserved1001
EWS/FLI fusion protein5005
cytochrome P450 2D67007
glucocerebrosidase3003
Rac1 protein0011
IDH16006
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
DNA polymerase iota isoform a (long)5005
DNA polymerase kappa isoform 12002
muscarinic acetylcholine receptor M12002
lethal factor (plasmid)2002
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0202
Fatty acid-binding protein, liver0101
Integrin beta-33205
Myeloperoxidase0101
Prostaglandin G/H synthase 10202
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb3205
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10606
Substance-P receptor0101
Prostaglandin G/H synthase 20202
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Nuclear receptor ROR-gamma4116
Ras-related protein Rab-2A0011
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Sigma non-opioid intracellular receptor 10617
Sigma non-opioid intracellular receptor 10112
pregnane X nuclear receptor110011
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta3003
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0303
5-hydroxytryptamine receptor 40808
Muscarinic acetylcholine receptor M206110
Muscarinic acetylcholine receptor M40518
Muscarinic acetylcholine receptor M10316
Muscarinic acetylcholine receptor M30215
Muscarinic acetylcholine receptor M40215
Muscarinic acetylcholine receptor M50215
Muscarinic acetylcholine receptor M507110
Muscarinic acetylcholine receptor M20216
Muscarinic acetylcholine receptor M107111
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M308111
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2C0808
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor2104
5-hydroxytryptamine receptor 70202
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0112
thyroid stimulating hormone receptor8008
Cellular tumor antigen p53150015
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20213
Potassium channel subfamily K member 90101
Chain A, BCL-2-RELATED PROTEIN A10011
glp-1 receptor, partial3003
Fumarate hydratase3003
Smad31001
farnesoid X nuclear receptor100010
G8008
polyprotein3003
67.9K protein2002
cellular tumor antigen p53 isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 24004
thyroid hormone receptor beta isoform 29009
huntingtin isoform 22002
tyrosine-protein kinase Yes1001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
nuclear receptor ROR-gamma isoform 15005
relaxin receptor 1 isoform 11001
bcl-2-like protein 11 isoform 10011
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Interferon beta100010
HLA class I histocompatibility antigen, B alpha chain 8008
Deoxycytidine kinase0001
Adenosine receptor A30101
Rap guanine nucleotide exchange factor 41001
Inositol hexakisphosphate kinase 18008
ATPase family AAA domain-containing protein 57007
Ataxin-28008
cytochrome P450 2C9, partial8008
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Amyloid-beta precursor protein0202
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10314
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20314
D0101
5-hydroxytryptamine receptor 1A0404
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Liver carboxylesterase 10102
Sodium-dependent noradrenaline transporter 0819
Sodium-dependent dopamine transporter0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Gamma-aminobutyric acid receptor subunit beta-30314
5-hydroxytryptamine receptor 1B0404
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50213
Sodium-dependent serotonin transporter0628
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30213
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20213
Gamma-aminobutyric acid receptor subunit beta-20213
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit epsilon0202
Glutamate receptor ionotropic, NMDA 2A 0101
Glutamate receptor ionotropic, NMDA 2C0101
Sodium-dependent dopamine transporter 0617
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
Potassium voltage-gated channel subfamily H member 20505
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60213
Sodium-dependent dopamine transporter0303
Glutamate receptor ionotropic, NMDA 2D0101
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10202
Glutamate receptor ionotropic, NMDA 3B0101
Gamma-aminobutyric acid receptor subunit gamma-30202
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0101
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0303
caspase 7, apoptosis-related cysteine protease3003
estrogen receptor 2 (ER beta)4004
progesterone receptor8008
regulator of G-protein signaling 45005
peroxisome proliferator activated receptor gamma100010
caspase-33003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
Caspase-73003
NPC intracellular cholesterol transporter 1 precursor2002
chromobox protein homolog 17007
potassium voltage-gated channel subfamily H member 2 isoform d3003
caspase-33003
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A2002
serine/threonine-protein kinase mTOR isoform 12002
Sodium-dependent noradrenaline transporter0101
Albumin0011
Sodium channel protein type 1 subunit alpha0101
Aldo-keto reductase family 1 member B10707
ATP-dependent translocase ABCB10517
Alpha-2A adrenergic receptor0303
Angiotensin-converting enzyme0404
Dipeptidyl peptidase 40101
Alpha-1B adrenergic receptor0606
Alpha-2B adrenergic receptor0404
Acetylcholinesterase0101
Acetylcholinesterase0101
Alpha-1D adrenergic receptor0303
Potassium voltage-gated channel subfamily C member 10101
5-hydroxytryptamine receptor 2A0404
Alpha-1A adrenergic receptor0606
5-hydroxytryptamine receptor 60404
Cytochrome P450 2J20101
Spike glycoprotein6017
Gastrin/cholecystokinin type B receptor 0101
Cytochrome P450 1B10101
Sodium-dependent serotonin transporter0101
Transporter0101
Nuclear receptor subfamily 3 group C member 3 0404
Beta-2 adrenergic receptor0101
Histamine H3 receptor0101
Luciferase3003
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
vitamin D3 receptor isoform VDRA6006
Chain A, Cruzipain4004
Albumin0112
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Chymotrypsinogen A0101
ATP-dependent phosphofructokinase2002
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
SMAD family member 24004
SMAD family member 34004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
PINK12002
Parkin3003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Glucocorticoid receptor0415
Glycine receptor subunit alpha-10404
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
pregnane X receptor5005
nonstructural protein 13003
nuclear receptor subfamily 1, group I, member 21001
transcriptional regulator ERG isoform 33003
cytochrome P450 3A4 isoform 14004
Estrogen receptor0326
Sex hormone-binding globulin0011
Progesterone receptor0314
Mineralocorticoid receptor 0101
Androgen receptor0224
Androgen receptor0011
Histamine H2 receptor0404
Alpha-synuclein2103
Aldo-keto reductase family 1 member C30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G2002
Aldo-keto reductase family 1 member C10101
Estrogen receptor beta0325
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, JmjC domain-containing histone demethylation protein 3A2002
phosphopantetheinyl transferase4004
thioredoxin glutathione reductase3003
apical membrane antigen 1, AMA12002
bromodomain adjacent to zinc finger domain 2B3003
aryl hydrocarbon receptor4004
hemoglobin subunit beta1001
histone acetyltransferase KAT2A isoform 12002
UDP-glucose 6-dehydrogenase0101
Solute carrier family 22 member 80001
Hypoxanthine-guanine phosphoribosyltransferase0001
UDP-glucose 6-dehydrogenase0101
Purine nucleoside phosphorylase0011
UDP-glucuronosyltransferase 1A1 0101
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
acetylcholinesterase2002
dopamine D1 receptor1001
USP1 protein, partial4004
flap endonuclease 11001
Rap guanine nucleotide exchange factor 31001
TAR DNA-binding protein 432002
Chain A, Ferritin light chain5005
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
heat shock protein HSP 90-alpha isoform 20001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
heat shock protein 90, putative0001
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90002
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
5-hydroxytryptamine receptor 2B0606
Sodium- and chloride-dependent betaine transporter0101
UDP-glucuronosyltransferase 1A80001
Solute carrier family 22 member 10101
Solute carrier family 22 member 20102
Solute carrier organic anion transporter family member 1A40101
Solute carrier family 22 member 20101
Histidine-rich protein PFHRP-II0101
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
Solute carrier organic anion transporter family member 1A10101
Solute carrier family 22 member 10203
Cytochrome P450 2D40101
Solute carrier family 22 member 20202
Chain A, CES1 protein0101
PPM1D protein2002
DNA polymerase III, partial1001
thyrotropin-releasing hormone receptor2002
Spike glycoprotein0011
Replicase polyprotein 1ab0011
cytochrome P450 2D6 isoform 11001
interferon gamma precursor0001
ubiquitin-conjugating enzyme E2 N0101
M-phase phosphoprotein 82002
streptokinase A precursor0011
Transmembrane protease serine 20011
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Receptor tyrosine-protein kinase erbB-20101
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Procathepsin L0011
Beta-1 adrenergic receptor0202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Adenosine receptor A30404
Replicase polyprotein 1ab0011
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Protein kinase C alpha type0101
Substance-K receptor0202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
UDP-glucuronosyltransferase 1A40001
Thromboxane-A synthase 0101
Protein kinase C eta type0101
Substance-P receptor0202
Adenosine receptor A2a0202
B2 bradykinin receptor0202
Adenosine receptor A10202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Delta-type opioid receptor0303
Kappa-type opioid receptor0202
Protein kinase C iota type0101
Melanocortin receptor 30202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
Chain A, Nuclear Receptor ROR-beta0101
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)0101
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)0101
Chain A, Histone deacetylase 7a0101
Chain A, Histone deacetylase 7a0101
Histone deacetylase 80101
Histone deacetylase 0101
Lysine-specific demethylase 4E0101
unnamed protein product0001
Histone deacetylase 10202
Histone deacetylase 30406
5-hydroxytryptamine receptor 3A0101
Histone deacetylase 30101
Plasma kallikrein0101
Coagulation factor VII0101
Leukotriene A-4 hydrolase0101
Vitamin D3 receptor0101
Tissue factor0202
Adenosine receptor A10101
Histone deacetylase 40418
Histone deacetylase 20101
Histone deacetylase 10428
Splicing factor 3B subunit 30101
Histone deacetylase 10101
Adenosine receptor A10101
Histone deacetylase 0101
Histone deacetylase 40101
Polyamine deacetylase HDAC100101
Histone deacetylase 30101
Histone deacetylase-like amidohydrolase0202
Histone deacetylase 70101
NAD-dependent protein deacetylase sirtuin-60112
Histone deacetylase 80101
Histone deacetylase 70406
Histone deacetylase 110101
Histone deacetylase 20417
HD2 type histone deacetylase HDA106 0202
Polyamine deacetylase HDAC100406
Histone deacetylase 11 0406
Histone deacetylase 90101
Histone deacetylase 70101
Histone deacetylase 6 0101
Histone deacetylase 40101
Histone deacetylase 80406
Histone deacetylase 60417
Histone deacetylase 90406
Histone deacetylase 50406
Histone deacetylase 0101
Nuclear receptor corepressor 20202
Histone deacetylase 60101
Histone deacetylase 50101
Histone deacetylase 0101
Cocaine esterase0101
Bile salt export pump0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60001
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]