Cranial Nerve III Diseases

Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)

Synonym
Oculomotor Nerve Palsy
Total Third-Nerve Palsy
Oculomotor Nerve Paralysis
Oculomotor Neuropathy
Partial Third-Nerve Palsy
Cranial Nerve III Diseases
Third Cranial Nerve Diseases
Third-Nerve Palsy
Oculomotor Nerve Diseases
Oculomotor Nerve Disorders
Third-Nerve Paralysis

Excerpt	Reference
"An isolated oculomotor nerve palsy is very rarely the presenting sign of pituitary apoplexy."	( Carter, WA; Cho, AS; Lee, CC, 2000)
"Oculomotor nerve palsy is a rare finding in children and, when reported, is most frequently either congenital or acquired from postnatal trauma, infection, aneurysm, or migraine."	( Bogie, A; Crittenden-Byers, C; Malone, JR, 2012)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	4 (1.84)	23.3326
1990's	34 (15.67)	12.5806
2000's	79 (36.41)	18.1394
2010's	84 (38.71)	28.8240
2020's	16 (7.37)	9.53

Drug	Relationship Strength	Studies	Trials
choline	low	1	0
creatine	low	1	0
lactic acid	low	1	0
methanol	low	1	0
pyrazinamide	low	1	0
thiamine	low	1	0
acetazolamide	low	2	0
albendazole	low	3	0
aspirin	low	5	0
azathioprine	low	2	0
bupivacaine	low	1	0
verapamil	low	2	0
carbamazepine	low	7	0
clonazepam	low	1	0
pentetic acid	low	2	0
brl 42810	low	1	0
fentanyl	low	1	0
flucytosine	low	1	0
foscarnet	low	1	0
guaifenesin	low	1	0
p-hydroxyamphetamine	low	1	0
lidocaine	low	1	0
iothalamic acid	low	1	0
2-propanol	low	14	0
ketoconazole	low	1	0
labetalol	low	1	0
meperidine	low	1	0
methylphenidate	low	1	0
metronidazole	low	1	0
neostigmine	low	1	0
papaverine	low	1	0
praziquantel	low	1	0
propofol	low	1	0
succinylcholine	low	1	0
sumatriptan	low	1	0
thalidomide	low	1	0
ticlopidine	low	2	0
prednisolone	low	11	0
prednisolone acetate	low	1	0
prednisone	low	16	0
penicillin g	low	3	0
pilocarpine	low	5	0
aspartic acid	low	1	0
lysine	low	1	0
levodopa	low	2	0
leucine	low	1	0
mannitol	low	1	0
cytarabine	low	3	0
arginine	low	1	0
methylprednisolone	medium	20	1
pyridostigmine bromide	low	2	0
galantamine	low	1	0
betamethasone	low	1	0
2-aminopurine	low	1	0
deoxycytidine	low	1	0
ethambutol	low	1	0
gadolinium	low	9	0
gold	low	2	0
magnesium sulfate	low	1	0
bromocriptine	low	1	0
glutamic acid	low	1	0
amoxicillin	low	1	0
oxcarbazepine	low	1	0
paclitaxel	low	1	0
etoposide	low	1	0
ribavirin	low	1	0
propiconazole	low	33	0
atracurium	low	1	0
nicorandil	low	2	0
fomesafen	low	1	0
cabergoline	low	2	0
itraconazole	low	1	0
clopidogrel	low	1	0
gemcitabine	low	1	0
plerixafor	low	1	0
oseltamivir	low	2	0
n-acetylaspartic acid	low	1	0
fluorodeoxyglucose f18	low	1	0
methotrexate	low	6	0
atropine	low	1	0
ropivacaine	low	2	0
trimethoprim, sulfamethoxazole drug combination	low	2	0
inositol 3-phosphate	low	1	0
meropenem	low	1	0
tacrolimus	low	1	0
cocaine	low	1	0
mycophenolic acid	low	1	0
flunarizine	low	1	0
vitamin k semiquinone radical	low	1	0
amphotericin b	low	1	0
coenzyme q10	low	2	0
isotretinoin	low	1	0
phenylephrine hydrochloride	low	5	0
ganglioside, gd1b	low	1	0
gadolinium dtpa	low	6	0
ergoline	low	2	0
mocetinostat	low	1	0
g(m1) ganglioside	low	2	0
amenamevir	low	1	0
clove	low	1	0
ubiquinone	low	2	0
ro13-9904	low	3	0
galactocerebroside	low	1	0
minocycline	low	1	0
vitamin b 12	medium	1	1
cyclosporine	low	1	0
acyclovir	low	7	0
levoleucovorin	low	1	0
rifampin	low	1	0
valacyclovir	low	1	0
sildenafil citrate	low	1	0
eye	low	6	0
gq1b ganglioside	low	6	0

Protein Targets (1,140)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Beta-lactamase	13	0	0	13
thioredoxin reductase	25	0	0	25
aldehyde dehydrogenase 1 family, member A1	21	0	0	21
IDH1	14	0	0	14
Phosphatidylinositol 4-kinase alpha	0	2	0	2
Xanthine dehydrogenase/oxidase	0	1	0	1
Guanine nucleotide-binding protein G	3	0	0	3
TAR DNA-binding protein 43	6	0	0	6
Phosphatidylinositol 4-kinase type 2-beta	0	2	0	2
Phosphatidylinositol 4-kinase type 2-alpha	0	2	0	2
Phosphatidylinositol 4-kinase beta	0	2	0	2
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
RAR-related orphan receptor gamma	25	0	0	25
GLI family zinc finger 3	28	0	0	28
AR protein	45	0	0	45
retinoic acid nuclear receptor alpha variant 1	25	0	0	25
retinoid X nuclear receptor alpha	21	0	0	21
estrogen nuclear receptor alpha	49	0	0	49
peroxisome proliferator-activated receptor delta	19	0	0	19
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	19	0	0	19
activating transcription factor 6	11	0	0	11
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
Histone H2A.x	15	0	0	15
thyroid hormone receptor beta isoform a	12	0	0	12
heat shock protein beta-1	10	0	0	10
nuclear factor erythroid 2-related factor 2 isoform 1	26	0	0	26
lamin isoform A-delta10	32	0	0	32
Voltage-dependent calcium channel gamma-2 subunit	14	0	0	14
Glutamate receptor 2	14	3	1	18
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	11	0	0	11
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
GALC protein	5	0	0	5
nuclear receptor subfamily 1, group I, member 3	23	0	0	23
cytochrome P450 family 3 subfamily A polypeptide 4	25	0	0	25
glucocorticoid receptor [Homo sapiens]	38	0	0	38
estrogen-related nuclear receptor alpha	31	0	0	31
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	14	0	0	14
Carbonic anhydrase	0	1	0	1
euchromatic histone-lysine N-methyltransferase 2	39	0	0	39
Bloom syndrome protein isoform 1	16	0	0	16
geminin	34	0	0	34
peripheral myelin protein 22	18	0	0	18
survival motor neuron protein isoform d	10	0	0	10
muscleblind-like protein 1 isoform 1	9	0	0	9
Gamma-aminobutyric acid receptor subunit pi	12	3	1	16
ATP-binding cassette sub-family C member 3	0	41	0	41
Multidrug resistance-associated protein 4	0	41	0	43
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	3	0	4
Carbonic anhydrase 12	0	2	1	7
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Bile salt export pump	0	51	0	51
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	2	0	2
Carbonic anhydrase 1	0	7	1	17
Carbonic anhydrase 2	0	8	2	17
Carbonic anhydrase 2	0	2	0	2
Cytochrome P450 1A2	0	2	0	2
Carbonic anhydrase 3	0	2	1	7
Cathepsin B	0	1	0	1
Cytochrome P450 3A4	0	13	0	15
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	5	0	6
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cytochrome P450 2C8	0	5	0	5
Cytochrome P450 2D6	0	5	0	5
Cytochrome P450 2A6	0	3	1	4
Cytochrome P450 2C9	0	13	0	13
5-hydroxytryptamine receptor 2A	0	6	0	6
Androgen receptor	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-1	12	3	1	16
Translocator protein	0	2	0	2
Gamma-aminobutyric acid receptor subunit delta	12	3	1	16
Gamma-aminobutyric acid receptor subunit gamma-2	12	3	1	16
Gamma-aminobutyric acid receptor subunit alpha-5	12	3	1	16
Gamma-aminobutyric acid receptor subunit alpha-3	12	3	1	16
Cannabinoid receptor 1	0	1	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
Cytochrome P450 2B6	0	4	2	6
Carbonic anhydrase 4	0	3	1	7
Carbonic anhydrase 6	0	3	1	7
Gamma-aminobutyric acid receptor subunit gamma-1	12	3	1	16
Gamma-aminobutyric acid receptor subunit alpha-2	12	3	1	16
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	2	0	3
Serum paraoxonase/arylesterase 1	0	3	0	3
Dipeptidyl peptidase 4	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	12	3	1	16
Gamma-aminobutyric acid receptor subunit gamma-3	12	3	1	16
Endochitinase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	12	3	1	16
Adenosine receptor A2a	0	2	0	3
5-hydroxytryptamine receptor 2B	0	3	0	3
Sodium-dependent serotonin transporter	0	6	0	7
Delta-type opioid receptor	0	7	0	7
Cytochrome P450 2C19	0	7	0	7
Delta-type opioid receptor	0	4	0	4
Mu-type opioid receptor	0	5	1	6
Carbonic anhydrase 5A, mitochondrial	0	3	1	8
Carbonic anhydrase	0	1	0	2
Kappa-type opioid receptor	0	5	0	7
Carbonic anhydrase 7	0	2	1	6
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	1	1	0	2
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	2
D(2) dopamine receptor	0	6	1	7
Gamma-aminobutyric acid receptor subunit alpha-1	12	4	1	17
Gamma-aminobutyric acid receptor subunit beta-3	12	3	1	16
Gamma-aminobutyric acid receptor subunit beta-2	12	3	1	16
Cholinesterase	0	4	0	4
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Fatty-acid amide hydrolase 1	0	4	0	4
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	5	1	8
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase 9	0	3	1	8
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	3
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	2
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	4
GABA theta subunit	12	3	1	16
Canalicular multispecific organic anion transporter 1	0	42	0	43
Carbonic anhydrase 4	0	2	0	3
Carbonic anhydrase 15	0	1	0	3
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 13	0	2	0	5
Carbonic anhydrase 7	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	12	3	1	16
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 14	0	2	1	7
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	2	1	7
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	10	0	0	10
Chain B, HADH2 protein	10	0	0	10
Chain A, ATP-DEPENDENT DNA HELICASE Q1	3	0	0	3
Chain A, Ferritin light chain	10	0	0	10
Thymidine kinase	0	1	0	1
phosphopantetheinyl transferase	14	0	0	14
GLS protein	14	0	0	14
TDP1 protein	32	0	0	32
Smad3	2	0	0	2
thyroid stimulating hormone receptor	14	0	0	14
EWS/FLI fusion protein	23	0	0	23
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	3	0	0	3
ubiquitin carboxyl-terminal hydrolase 2 isoform a	4	0	0	4
Solute carrier family 22 member 1	0	7	0	11
Bile salt export pump	0	12	0	12
Purine nucleoside phosphorylase	0	1	0	1
Thymidine kinase, cytosolic	0	1	0	2
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2J2	0	11	0	11
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Purine nucleoside phosphorylase	0	0	1	1
Solute carrier family 22 member 6	0	0	0	2
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	1	0	4
Thymidine kinase	0	2	0	2
Luciferase	9	0	0	9
glp-1 receptor, partial	12	0	0	12
ATAD5 protein, partial	12	0	0	12
Fumarate hydratase	6	0	0	6
caspase 7, apoptosis-related cysteine protease	4	0	0	4
progesterone receptor	18	0	0	18
farnesoid X nuclear receptor	17	0	0	17
pregnane X nuclear receptor	29	0	0	29
polyprotein	6	0	0	6
67.9K protein	10	0	0	10
peroxisome proliferator activated receptor gamma	21	0	0	21
vitamin D (1,25- dihydroxyvitamin D3) receptor	16	0	0	16
caspase-3	4	0	0	4
aryl hydrocarbon receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
cellular tumor antigen p53 isoform a	5	0	0	5
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	7	0	0	7
chromobox protein homolog 1	24	0	0	24
nuclear factor erythroid 2-related factor 2 isoform 2	16	0	0	16
transcriptional regulator ERG isoform 3	4	0	0	4
thyroid hormone receptor beta isoform 2	25	0	0	25
histone deacetylase 9 isoform 3	1	0	0	1
mitogen-activated protein kinase 1	6	0	0	6
urokinase-type plasminogen activator precursor	7	0	0	7
plasminogen precursor	7	0	0	7
urokinase plasminogen activator surface receptor precursor	7	0	0	7
Vif	0	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
neuropeptide S receptor isoform A	2	0	0	2
Interferon beta	20	0	0	20
Cellular tumor antigen p53	27	0	0	27
Integrin beta-3	3	2	1	6
Integrin alpha-IIb	3	1	1	5
Methionine aminopeptidase	0	1	0	1
Inositol monophosphatase 1	2	0	0	2
ATPase family AAA domain-containing protein 5	15	0	0	15
Ataxin-2	19	0	0	19
Thromboxane-A synthase	0	3	0	3
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	21	0	0	21
Chain A, 2-oxoglutarate Oxygenase	12	0	0	12
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
apical membrane antigen 1, AMA1	3	0	0	3
Beta-lactamase	0	0	0	2
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	9	0	0	9
DNA polymerase eta isoform 1	5	0	0	5
DNA polymerase iota isoform a (long)	17	0	0	17
DNA polymerase kappa isoform 1	10	0	0	10
Beta-lactamase SHV-1	0	0	0	2
Beta-lactamase SHV-1	0	0	0	3
Beta-lactamase	0	0	0	3
Solute carrier family 15 member 1	0	7	0	8
Solute carrier family 15 member 1	0	3	0	3
B2 metallo-beta-lactamase	0	0	0	3
Solute carrier family 15 member 2	0	3	0	3
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Solute carrier family 15 member 2	0	4	0	4
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain A, Cruzipain	5	0	0	5
interleukin 8	6	0	0	6
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	11	0	0	11
Nuclear receptor ROR-gamma	6	0	0	6
Potassium voltage-gated channel subfamily H member 2	0	12	0	12
Aurora kinase B	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	4	1	6
Chain A, Mutant Al2 6e7p9g	0	0	1	1
Beta-lactamase	0	0	0	2
acid sphingomyelinase	2	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase type 2	0	0	1	4
Metallo-beta-lactamase VIM-11	0	0	0	3
Metallo-beta-lactamase VIM-2	0	0	0	3
Beta-lactamase	0	0	0	3
Metallo-beta-lactamase	0	0	0	3
Beta-lactamase	0	0	0	2
DNA polymerase beta	3	0	0	3
60 kDa heat shock protein, mitochondrial	0	4	0	4
Beta-lactamase OXA-7	0	0	0	1
Spike glycoprotein	15	0	2	17
10 kDa heat shock protein, mitochondrial	0	4	0	4
Angiopoietin-1 receptor	0	0	1	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Thiosulfate sulfurtransferase	0	4	0	4
Metallo-beta-lactamase VIM-13	0	0	0	3
Efflux transporter	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase Toho-1	0	0	0	2
Beta-lactamase	0	0	0	2
Class D beta-lactamase	0	0	0	2
60 kDa chaperonin	0	4	0	4
Metallo-beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	1	4
10 kDa chaperonin	0	4	0	4
Metallo-b-lactamase	0	0	0	3
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	3
Histamine H3 receptor	0	0	0	2
Beta-lactamase class B VIM-2	0	0	1	4
Beta-lactamase VIM-1	0	0	0	3
ATP-dependent phosphofructokinase	13	0	0	13
USP1 protein, partial	13	0	0	13
Nicotinate phosphoribosyltransferase	0	2	0	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	3	0	0	3
alpha-galactosidase	4	0	0	4
cytochrome P450 2C19 precursor	7	0	0	7
flap endonuclease 1	8	0	0	8
muscarinic acetylcholine receptor M1	11	0	0	11
lethal factor (plasmid)	7	0	0	7
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	2	0	2
Metabotropic glutamate receptor 6	0	1	2	4
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	3	1	6
Glutamate receptor ionotropic, NMDA 1	0	4	1	7
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	4	1	7
Glutamate receptor ionotropic, NMDA 2C	0	4	1	7
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	3
Glutamate receptor ionotropic, NMDA 2D	0	4	1	7
Glutamate receptor ionotropic, NMDA 3B	0	4	1	7
Glutamate receptor ionotropic, NMDA 3A	0	4	1	7
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	1	0	0	1
cytochrome P450 2D6	10	0	0	10
glucocerebrosidase	3	0	0	3
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Epidermal growth factor receptor	0	4	0	4
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	10	1	11
Sigma non-opioid intracellular receptor 1	0	1	1	2
NPYLR7B	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Small conductance calcium-activated potassium channel protein 3	0	2	1	3
cystic fibrosis transmembrane conductance regulator	0	1	0	1
short transient receptor potential channel 6 isoform 1	0	0	1	1
5-hydroxytryptamine receptor 4	0	12	0	12
Muscarinic acetylcholine receptor M2	0	5	2	10
Muscarinic acetylcholine receptor M4	0	4	1	7
Muscarinic acetylcholine receptor M1	0	5	1	9
Muscarinic acetylcholine receptor M3	0	4	1	8
Muscarinic acetylcholine receptor M4	0	4	1	8
Muscarinic acetylcholine receptor M5	0	4	1	8
Muscarinic acetylcholine receptor M5	0	5	1	8
Muscarinic acetylcholine receptor M2	0	4	1	9
Muscarinic acetylcholine receptor M1	0	5	3	11
Muscarinic acetylcholine receptor M1	0	0	1	2
Muscarinic acetylcholine receptor M3	0	4	1	7
Alpha-1D adrenergic receptor	0	10	1	11
5-hydroxytryptamine receptor 2C	0	13	1	14
Muscarinic acetylcholine receptor M4	0	1	0	1
Histamine H2 receptor	6	0	0	7
5-hydroxytryptamine receptor 7	0	2	0	2
Reverse transcriptase/RNaseH	0	1	2	4
Muscarinic acetylcholine receptor	0	1	1	2
acetylcholinesterase	11	0	0	11
SMAD family member 2	9	0	0	9
SMAD family member 3	9	0	0	9
Microtubule-associated protein tau	9	0	0	9
thioredoxin glutathione reductase	6	0	0	6
G	13	0	0	13
P53	1	0	0	1
thyroid stimulating hormone receptor	8	0	0	8
peripheral myelin protein 22 isoform 1	6	0	0	6
cytochrome P450 3A4 isoform 1	12	0	0	12
M-phase phosphoprotein 8	6	0	0	6
HLA class I histocompatibility antigen, B alpha chain	13	0	0	13
Inositol hexakisphosphate kinase 1	13	0	0	13
Protein-arginine deiminase type-4	0	4	0	4
cytochrome P450 2C9, partial	13	0	0	13
pregnane X receptor	6	0	0	6
galanin receptor type 3	0	1	0	1
Glucocorticoid receptor	0	10	2	17
Glycine receptor subunit alpha-1	0	10	0	10
Glycine receptor subunit beta	0	10	0	10
Glycine receptor subunit alpha-2	0	10	0	10
Glycine receptor subunit alpha-3	0	10	0	10
ORF73	0	0	1	1
relaxin receptor 1 isoform 1	1	0	0	1
Genome polyprotein	0	1	1	2
dopamine D1 receptor	4	0	0	4
regulator of G-protein signaling 4	7	0	0	7
D(1A) dopamine receptor	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	4	0	0	4
ATP-dependent translocase ABCB1	0	6	0	6
ATP-dependent translocase ABCB1	0	11	1	23
Beta-1 adrenergic receptor	0	6	1	7
5-hydroxytryptamine receptor 1A	0	3	1	4
Alpha-2A adrenergic receptor	0	13	0	13
D(2) dopamine receptor	0	8	1	9
Alpha-2B adrenergic receptor	0	12	0	12
Alpha-2C adrenergic receptor	0	8	0	8
D	0	2	0	2
D(3) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	13	1	14
Alpha-2B adrenergic receptor	0	3	1	4
ATP-dependent translocase ABCB1	0	7	0	8
D(1A) dopamine receptor	0	6	0	6
Alpha-2C adrenergic receptor	0	3	1	4
Alpha-2A adrenergic receptor	0	3	1	4
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	10	1	11
5-hydroxytryptamine receptor 1B	0	13	0	13
D(4) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	9	0	9
Alpha-synuclein	1	2	0	3
5-hydroxytryptamine receptor 2B	0	15	1	16
5-hydroxytryptamine receptor 6	0	4	0	4
Potassium channel subfamily K member 3	0	3	0	3
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	2	3
Potassium channel subfamily K member 9	0	1	0	1
Histamine H3 receptor	0	1	0	1
Vpr	3	0	0	3
Albumin	0	0	1	1
Major prion protein	0	0	1	1
Sodium channel protein type 1 subunit alpha	0	3	0	3
Sodium channel protein type 2 subunit alpha	0	4	0	4
Sodium channel protein type 3 subunit alpha	0	3	0	3
UDP-glucuronosyltransferase 2B7	0	2	0	6
Sodium channel protein type 4 subunit alpha	0	2	0	3
Sodium channel protein type 9 subunit alpha	0	3	0	3
Frizzled-8	0	0	1	1
P2X purinoceptor 4	0	2	0	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Acetylcholinesterase	0	0	2	2
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	1	0	2
Solute carrier family 22 member 2	0	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	1	2	0	3
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	1	2	0	3
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	7	1	9
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Solute carrier family 22 member 1	0	2	0	3
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	4	1	5
Gamma-aminobutyric acid receptor subunit beta-1	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-2	0	4	1	5
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	4	1	5
Translocator protein	0	1	0	1
Translocator protein	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit beta-2	0	3	1	4
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	1	4
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	1	4
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
nonstructural protein 1	7	0	0	7
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
Liver carboxylesterase 1	0	1	0	5
Sodium-dependent serotonin transporter	0	12	0	12
Rap guanine nucleotide exchange factor 4	3	0	0	3
P2Y purinoceptor 12	0	1	0	1
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Amyloid-beta precursor protein	1	2	0	3
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	1	2
Tryptophan 5-hydroxylase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	12	0	12
Sodium-dependent dopamine transporter	0	5	0	5
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	3	0	3
5-hydroxytryptamine receptor 1D	0	2	1	3
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	0	2
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Sodium-dependent dopamine transporter	0	10	0	10
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	3	0	3
Leukotriene B4 receptor 1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	0	2
Leukotriene B4 receptor 2	0	1	0	1
Transporter	0	3	0	3
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	3
endonuclease IV	4	0	0	4
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	3	0	3
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	3	0	3
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	1	0	1
Thymidylate synthase	0	3	0	4
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	3
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
histone-lysine N-methyltransferase 2A isoform 2 precursor	2	0	0	2
nuclear receptor ROR-gamma isoform 1	6	0	0	6
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
UDP-glucuronosyltransferase 1A9	0	0	0	5
UDP-glucuronosyltransferase 2B17	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	1	0	3
UDP-glucuronosyltransferase 1A1	0	2	0	5
UDP-glucuronosyltransferase 1A7	0	0	0	2
Adenylate cyclase	0	1	0	1
Tyrosine-protein kinase Lck	0	2	0	2
Tyrosine-protein kinase Fyn	0	3	0	3
Beta-2 adrenergic receptor	0	4	1	5
5-hydroxytryptamine receptor 1B	0	3	1	4
5-hydroxytryptamine receptor 5A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	3
Pantothenate synthetase	0	1	0	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	8	0	0	8
Prothrombin	0	0	1	2
Regulatory protein E2	0	0	1	1
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	1	1	7
Polyunsaturated fatty acid lipoxygenase ALOX15	0	5	0	5
DNA topoisomerase 2	0	0	0	1
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	1	8
Tubulin beta-2B chain	0	1	1	4
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	1	4
Similar to alpha-tubulin isoform 1	0	1	0	3
Solute carrier organic anion transporter family member 1B3	0	6	0	8
potassium voltage-gated channel subfamily H member 2 isoform d	10	0	0	10
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
Amine oxidase [flavin-containing] A	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Kappa-type opioid receptor	0	2	0	2
Histamine H1 receptor	0	3	0	3
Mu-type opioid receptor	0	5	2	7
Delta-type opioid receptor	0	7	0	7
Kappa-type opioid receptor	0	3	0	3
Mu-type opioid receptor	0	2	0	2
Skn7p	0	0	0	2
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
serine/threonine-protein kinase PLK1	2	0	0	2
Rap guanine nucleotide exchange factor 3	4	0	0	4
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	2
estrogen receptor 2 (ER beta)	13	0	0	13
Voltage-dependent T-type calcium channel subunit alpha-1G	0	0	1	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	0	1	1
Aldo-keto reductase family 1 member B1	0	9	0	9
Adenosine receptor A3	0	5	0	5
Angiotensin-converting enzyme	0	2	0	2
Alpha-1B adrenergic receptor	0	6	0	6
Cannabinoid receptor 1	0	2	0	2
Alpha-1A adrenergic receptor	0	6	0	6
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Potassium channel subfamily K member 2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	0	1	1
Prostaglandin D2 receptor 2	0	1	0	1
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Thrombopoietin	3	0	0	3
huntingtin isoform 2	2	0	0	2
Solute carrier family 22 member 8	0	1	0	3
Aromatase	0	3	0	3
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
DNA polymerase delta catalytic subunit	0	1	0	1
P-selectin	0	1	0	1
Chain A, ACETYLCHOLINESTERASE	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
Acetylcholinesterase	0	3	0	3
Acetylcholinesterase	0	2	0	2
Cholinesterase	0	4	0	4
Vascular endothelial growth factor receptor 1	0	2	0	2
Acetylcholinesterase	0	2	0	2
Acetylcholinesterase	0	1	0	1
Vascular endothelial growth factor receptor 3	0	2	0	2
Vascular endothelial growth factor receptor 2	0	2	0	2
Acetylcholinesterase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carboxylic ester hydrolase	0	2	0	2
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Spike glycoprotein	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Transmembrane protease serine 2	0	0	2	2
Procathepsin L	0	0	2	2
Replicase polyprotein 1a	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Replicase polyprotein 1ab	0	0	2	2
Equilibrative nucleoside transporter 1	0	1	0	1
Angiotensin-converting enzyme 2	0	0	2	2
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	3	0	0	3
Metabotropic glutamate receptor 8	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Glutathione reductase, mitochondrial	0	4	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
ATP-citrate synthase	0	1	0	1
Glutamate receptor 1	0	3	1	4
Glutamate receptor 3	0	3	1	4
Glutamate receptor 4	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	0	1	1
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Alpha-ketoglutarate-dependent dioxygenase FTO	0	1	0	1
Parkin	1	0	0	1
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	1	0	1
Retinoic acid receptor gamma	0	1	0	1
Retinoic acid receptor beta	0	1	0	1
Cellular retinoic acid-binding protein 2	0	0	1	1
Mitogen-activated protein kinase 1	0	1	0	1
Retinoic acid receptor RXR-alpha	0	1	0	1
Retinoic acid receptor RXR-beta	0	1	0	1
Retinoic acid receptor RXR-gamma	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Mitogen-activated protein kinase 14	0	1	0	1
Olfactory receptor 51E2	0	1	0	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Estrogen receptor beta	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	1	0	1
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial	0	2	0	2
Cytochrome P450 26A1	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	2	0	2
Camphor 5-monooxygenase	0	0	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Beta-lactamase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	2	0	2
Epoxide hydrolase 1	0	0	0	1
Cytochrome P450 2C11	0	1	0	1
Steroid 21-hydroxylase	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Cytochrome P450 2A2	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Cytochrome P450 7A1	0	1	0	1
Cytochrome P450 11B2, mitochondrial	0	1	0	1
Estrogen receptor	0	1	0	1
Substance-K receptor	0	4	0	4
Histamine H2 receptor	0	4	0	4
Gonadotropin-releasing hormone receptor	0	1	1	2
Type-1 angiotensin II receptor	0	1	0	1
Malate dehydrogenase, cytoplasmic	0	1	0	1
Cytochrome P450 4F2	0	1	0	1
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	2	0	2
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial	0	1	0	1
Sodium/bile acid cotransporter	0	1	0	1
Lanosterol 14-alpha demethylase	0	4	1	5
Cytochrome P450 7A1	0	1	0	1
Lanosterol 14-alpha demethylase	0	2	0	2
Beta-1 adrenergic receptor	0	0	1	1
Beta-3 adrenergic receptor	0	0	1	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	0	1	1
Heparanase	0	0	1	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, AMINOPEPTIDASE	0	1	0	1
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
Phospholipase A-2-activating protein	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
15-lipoxygenase, partial	6	0	0	6
WRN	1	0	0	1
integrase, partial	0	1	0	1
lens epithelium-derived growth factor p75	0	1	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	8	0	0	8
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	2	0	0	2
glucokinase regulatory protein	2	0	0	2
importin subunit beta-1 isoform 1	2	0	0	2
snurportin-1	2	0	0	2
Polyphenol oxidase 2	0	0	0	1
Plasma kallikrein	0	0	0	1
Tyrosinase	0	1	0	1
SLC16A10 protein	0	0	0	1
Monocarboxylate transporter 10	0	0	0	1
phosphoglycerate kinase	1	0	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Multidrug and toxin extrusion protein 1	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Kappa-type opioid receptor	0	1	0	1
Metallo-beta-lactamase VIM-19	0	0	0	2
streptokinase A precursor	0	0	2	2
Beta-lactamase	0	0	0	2
Beta-lactamase TEM	0	1	0	3
Metallo-beta-lactamase VIM-2	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase IMP-1	0	0	0	2
BlaVIM-1	0	0	0	2
Beta-lactamase	0	0	0	2
Beta-lactamase	0	0	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
histone acetyltransferase KAT2A isoform 1	4	0	0	4
caspase-1 isoform alpha precursor	1	0	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Tyrosine-protein kinase ABL1	0	1	1	2
Thymidylate synthase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	2	4
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	0	1	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	2	1	5
Reduced folate transporter	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Solute carrier organic anion transporter family member 1A3	0	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	1	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Multidrug resistance associated protein	0	1	0	2
Solute carrier family 22 member 11	0	0	0	1
PPM1D protein	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Thioredoxin reductase	0	1	0	1
Flavodoxin	0	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	3	1	4
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	1	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	1	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	1	4
Albumin	0	0	4	4
Stromelysin-1	0	1	0	1
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
Histone deacetylase 3	0	4	0	4
Nuclear receptor corepressor 1	0	1	0	1
Integrin beta-1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Integrin alpha-4	0	1	0	1
Histone deacetylase 4	0	3	0	3
Histone deacetylase 1	0	4	0	4
Histone deacetylase 7	0	3	0	3
Histone deacetylase 2	0	4	0	4
Histone deacetylase 11	0	3	0	3
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	3	0	3
Histone deacetylase 5	0	3	0	3
Nuclear receptor corepressor 2	0	1	0	1
Chain A, Inosine-5'-Monophosphate Dehydrogenase 2	0	1	0	1
Inosine-5'-monophosphate dehydrogenase 2	0	2	0	2
Inosine-5'-monophosphate dehydrogenase 1	0	2	0	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Inosine-5'-monophosphate dehydrogenase	0	1	0	2
UDP-glucuronosyltransferase 1A10	0	0	0	1
UDP-glucuronosyltransferase 1A8	0	0	0	2
cytochrome P450 2C9 precursor	3	0	0	3
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	2	0	2
Sialidase	0	1	0	1
Acyl-CoA desaturase 1	0	1	0	1
Neuraminidase	0	2	0	2
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Neuraminidase	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
polyadenylate-binding protein 1	0	1	0	1
bcl-2-related protein A1	0	1	0	1
Beta-secretase 1	0	1	1	2
Trace amine-associated receptor 1	0	0	1	1
Genome polyprotein	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
Tubulin alpha-1A chain	0	0	1	2
Tubulin beta chain	0	0	1	1
Tubulin beta-4A chain	0	1	1	3
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Integrin alpha-V	0	1	0	1
Tubulin beta chain	0	1	1	3
60 kDa chaperonin	0	1	0	1
Tubulin alpha-3C chain	0	1	1	3
Botulinum neurotoxin type A	0	1	0	1
Apoptosis regulator Bcl-2	0	1	0	1
Fibroblast growth factor receptor 1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	1	0	2
Cholecystokinin receptor type A	0	2	0	2
Melanocortin receptor 5	0	2	0	2
UDP-glucuronosyltransferase 2B10	0	1	0	1
Tubulin alpha-1B chain	0	1	1	3
Tubulin alpha-4A chain	0	1	1	3
Tubulin beta-4B chain	0	1	1	3
Bcl-2-like protein 1	0	1	0	1
Tyrosine-protein kinase Mer	0	1	0	1
Tubulin beta-3 chain	0	2	1	4
Tubulin beta-2A chain	0	1	1	3
Beta-tubulin	0	1	0	1
Tubulin beta-8 chain	0	1	1	3
Tubulin alpha-3E chain	0	1	1	3
Tubulin alpha-1A chain	0	1	1	3
Tubulin alpha-1C chain	0	1	1	3
Tubulin beta-6 chain	0	1	1	3
Tubulin beta-2B chain	0	1	1	3
Tubulin beta-1 chain	0	1	1	3
Nucleotide-binding oligomerization domain-containing protein 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	7	0	8
Chain A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
cytochrome P450 2D6 isoform 1	2	0	0	2
atrial natriuretic peptide receptor 2 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
Serine hydroxymethyltransferase, mitochondrial	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
CREB-binding protein	1	0	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	2	0	2
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase 1	0	0	0	1
Beta-lactamase OXA-10	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 22 member 8	0	1	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	3	0	0	3
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Cytochrome P450 2A13	0	1	1	2
C-X-C chemokine receptor type 4	0	1	0	1
Atypical chemokine receptor 3	0	0	1	1
C-C chemokine receptor type 2	0	1	0	1
C-X-C chemokine receptor type 4	0	2	0	4
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b	0	0	1	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
heat shock protein 90, putative	0	0	0	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Fatty-acid amide hydrolase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NS5	0	0	1	1
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	1	1
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Caspase-1	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Carboxypeptidase M	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1E	0	1	0	1
5-hydroxytryptamine receptor 1F	0	2	1	3
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	0	1
5-hydroxytryptamine receptor 3C	0	1	0	1
5-hydroxytryptamine receptor 1B	0	1	0	1
Cytochrome P450 3A5	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Cereblon isoform 4	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Protein cereblon	0	2	1	4
Chain A, ykoF	0	0	1	1
Chain B, ykoF	0	0	1	1
Chain A, ThiT	0	0	1	1
Thiamine transporter ThiT	0	0	1	1
Transketolase	0	0	1	1
Thiamine-binding periplasmic protein	0	0	1	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Cocaine esterase	0	1	0	1
Tissue factor	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Polyamine deacetylase HDAC10	0	2	0	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
Histone deacetylase 9	0	2	0	2
D-alanyl-D-alanine dipeptidase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Glycoprotein	0	1	0	1
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(11)

Research Excerpts

Overview

Research

Studies (217)

Protein Targets (1,140)

Cranial Nerve III Diseases

Synonyms(11)

Research Excerpts

Overview

Research

Studies (217)

Drugs Studied (124)

Protein Targets (1,140)