| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| RAR-related orphan receptor gamma | 5 | 0 | 0 | 5 |
| GLI family zinc finger 3 | 4 | 0 | 0 | 4 |
| AR protein | 6 | 0 | 0 | 6 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
| peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 4 | 0 | 0 | 4 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform a | 3 | 0 | 0 | 3 |
| heat shock protein beta-1 | 2 | 0 | 0 | 2 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 3 | 0 | 0 | 3 |
| Carbonic anhydrase 1 | 0 | 1 | 0 | 2 |
| Carbonic anhydrase 2 | 0 | 2 | 0 | 3 |
| Alanine racemase, biosynthetic | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1D | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 1 | 2 |
| Proton-coupled amino acid transporter 1 | 0 | 1 | 0 | 1 |
| Adenosine deaminase | 0 | 0 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
| glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| cystic fibrosis transmembrane conductance regulator | 0 | 1 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| short transient receptor potential channel 6 isoform 1 | 0 | 0 | 1 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
| Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Muscarinic acetylcholine receptor M2 | 0 | 4 | 1 | 8 |
| Muscarinic acetylcholine receptor M4 | 0 | 4 | 1 | 7 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 2 | 6 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 2 | 6 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 2 | 6 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 2 | 6 |
| Muscarinic acetylcholine receptor M5 | 0 | 4 | 1 | 7 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 2 | 7 |
| Muscarinic acetylcholine receptor M1 | 0 | 4 | 1 | 8 |
| Muscarinic acetylcholine receptor M1 | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 4 | 1 | 7 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 0 | 0 | 1 |
| Muscarinic acetylcholine receptor | 0 | 1 | 1 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 1 | 0 | 0 | 1 |
| Chain A, serum paraoxonase | 0 | 1 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| Carbonic anhydrase 12 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 3 | 0 | 1 | 0 | 1 |
| Neutrophil cytosol factor 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 6 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5A, mitochondrial | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 7 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 9 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 13 | 0 | 1 | 0 | 1 |
| Poly [ADP-ribose] polymerase tankyrase-2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 14 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 5B, mitochondrial | 0 | 1 | 0 | 1 |
| P2Y purinoceptor 2 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 1 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 4 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 6 | 0 | 0 | 1 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| TDP1 protein | 6 | 0 | 0 | 6 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| progesterone receptor | 3 | 0 | 0 | 3 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 4 | 0 | 0 | 4 |
| EWS/FLI fusion protein | 5 | 0 | 0 | 5 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
| cytochrome P450 2D6 | 3 | 0 | 0 | 3 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 4 | 0 | 0 | 4 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 2 | 0 | 0 | 2 |
| caspase-3 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 3 | 0 | 0 | 3 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
| Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| thioredoxin reductase | 4 | 0 | 0 | 4 |
| arylsulfatase A | 3 | 0 | 0 | 3 |
| STE24 | 0 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 2 | 0 | 0 | 2 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 3 | 0 | 0 | 3 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| CAAX prenyl protease | 0 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| streptokinase A precursor | 0 | 0 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 3 | 1 | 1 | 5 |
| Trypsin | 0 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| DNA gyrase subunit A | 0 | 1 | 0 | 2 |
| DNA gyrase subunit B | 0 | 1 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit delta | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 3 | 1 | 1 | 5 |
| DNA gyrase subunit B | 0 | 1 | 0 | 2 |
| DNA gyrase subunit A | 0 | 1 | 0 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| GABA theta subunit | 3 | 1 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit epsilon | 3 | 1 | 1 | 5 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| NFKB1 protein, partial | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 0 | 1 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| Beta-2 adrenergic receptor | 0 | 2 | 1 | 3 |
| Beta-1 adrenergic receptor | 0 | 2 | 1 | 3 |
| Alpha-2A adrenergic receptor | 0 | 1 | 1 | 2 |
| Beta-3 adrenergic receptor | 0 | 2 | 1 | 3 |
| POU domain, class 2, transcription factor 1 | 0 | 0 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 1 | 1 | 2 |
| Alpha-2C adrenergic receptor | 0 | 1 | 1 | 2 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 0 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 1 | 1 | 2 |
| Alpha-1B adrenergic receptor | 0 | 1 | 1 | 2 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 0 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 2 | 0 | 0 | 2 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 1 | 2 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase | 0 | 0 | 1 | 1 |
| Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase | 0 | 0 | 1 | 1 |
| Chain A, Breast cancer type 1 susceptibility protein | 1 | 0 | 0 | 1 |
| Chain H, Immunoglobulin Igg1 Heavy chain | 0 | 0 | 1 | 1 |
| Chain L, Immunoglobulin Igg1 Lambda Light Chain | 0 | 0 | 1 | 1 |
| Chain A, DODECIN | 0 | 0 | 1 | 1 |
| Chain A, DODECIN | 0 | 0 | 1 | 1 |
| Chain C, DODECIN | 0 | 0 | 1 | 1 |
| Chain E, DODECIN | 0 | 0 | 1 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| NPYLR7B | 0 | 0 | 1 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| tumor necrosis factor | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 3 | 0 | 0 | 3 |
| caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Riboflavin-binding protein | 0 | 1 | 1 | 2 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| 60 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| 10 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Thiosulfate sulfurtransferase | 0 | 1 | 0 | 1 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| 10 kDa chaperonin | 0 | 1 | 0 | 1 |
| Luciferase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 1 | 0 | 1 |
| Free fatty acid receptor 1 | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 0 | 1 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Cytochrome P450 2C9 | 0 | 1 | 1 | 2 |
| Tyrosine-protein phosphatase non-receptor type 1 | 0 | 1 | 0 | 1 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Cytochrome P450 3A5 | 0 | 0 | 1 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Catechol O-methyltransferase | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | 0 | 1 | 1 | 2 |
| Carnitine O-palmitoyltransferase 2, mitochondrial | 0 | 1 | 0 | 1 |
| Thromboxane-A synthase | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 2 | 0 | 2 |
| Peroxisome proliferator-activated receptor gamma | 0 | 2 | 2 | 5 |
| Peroxisome proliferator-activated receptor gamma | 0 | 0 | 1 | 1 |
| C-C chemokine receptor type 2 | 0 | 1 | 0 | 1 |
| Cannabinoid receptor 2 | 0 | 0 | 1 | 1 |
| Carnitine O-palmitoyltransferase 1, liver isoform | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| Peroxisome proliferator-activated receptor delta | 0 | 2 | 1 | 3 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 0 | 1 | 1 |
| Peroxisome proliferator-activated receptor alpha | 0 | 2 | 1 | 3 |
| ATP-binding cassette sub-family C member 8 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 0 | 1 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 0 | 1 | 1 |
| ATP-sensitive inward rectifier potassium channel 11 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 0 | 1 | 1 |
| Sodium/bile acid cotransporter | 0 | 1 | 0 | 1 |
| Thrombin | 0 | 0 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 2 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 0 | 1 | 1 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 2 | 0 | 2 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| Beta-1 adrenergic receptor | 0 | 0 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| Beta-2 adrenergic receptor | 0 | 0 | 1 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| G | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Cytochrome P450 2C19 | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |