Page last updated: 2024-09-27

Corneal Endothelial Cell Damage

Loss of CORNEAL ENDOTHELIUM usually following intraocular surgery (e.g., cataract surgery) or due to FUCHS' ENDOTHELIAL DYSTROPHY; ANGLE-CLOSURE GLAUCOMA; IRITIS; or aging.

Synonyms(3)

Synonym
Corneal Endothelial Cell Loss
Corneal Endothelial Cell Damage
Endothelial Cell Loss, Corneal

Research Excerpts

Treatment

ExcerptReference
"To assess corneal endothelial cell loss after penetrating keratoplasty (PK) treatment for laser iridotomy (LI)-induced bullous keratopathy (BK)."( Kayukawa, K; Kinoshita, S; Koizumi, N; Kondo, M; Kusakabe, A; Mori, K; Okumura, N; Sotozono, C; Wakimasu, K, 2018)

Research

Studies (150)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's1 (0.67)18.1394
2010's128 (85.33)28.8240
2020's21 (14.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
beta-alanine0low10
glycine0low10
glycerol0low10
hydrogen carbonate0medium22
amantadine0low10
bupivacaine0low10
cefuroxime0low10
cyclopentolate0medium11
erythrosine0low60
gentamicin0medium51
lidocaine0medium31
2-propanol0medium351
metformin0low10
o-phthalaldehyde0low10
mitomycin0medium104
prednisolone0medium62
prednisolone acetate0medium52
fluprednisolone0low10
pilocarpine0low10
phenylephrine0medium11
cytidine0low10
mannitol0low10
alizarin0low10
perflutren0low20
sulfan blue0low10
fluorometholone0medium32
gentian violet0low20
c.i. 425100low10
vancomycin0low10
sulfur hexafluoride0medium121
Brilliant Blue0low10
phenyl acetate0low20
triamcinolone0low10
simvastatin0low10
fluorexon0low10
triazoles0low10
voriconazole0low10
n-acetylcytidine0low10
methotrexate0low10
tamsulosin0low10
proline0low10
moxifloxacin0medium32
atropine0low10
ropivacaine0low10
calcein am0low50
difluprednate0low10
loteprednol etabonate0medium21
zithromax0low10
y 276320low10
riboflavin0medium132
bromochloroacetic acid0low10
curcumin0low10
nitinol0low10
zeaxanthin0low10
lutein0low20
humulene0low10
5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine0low10
carbocyanines0low10
fg-45920low10
thymosin beta(4)0low10
thymosin0low10
methylcellulose0low10
vasoactive intestinal peptide0low10
ascorbic acid0low10
chondroitin sulfates0medium102
exudates0low10
acyclovir0low10
trypan blue0medium152
eye0low10

Protein Targets (706)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit9009
RAR-related orphan receptor gamma200020
GLI family zinc finger 3200020
AR protein300030
aldehyde dehydrogenase 1 family, member A18008
retinoic acid nuclear receptor alpha variant 1180018
retinoid X nuclear receptor alpha160016
estrogen nuclear receptor alpha280028
peroxisome proliferator-activated receptor delta110011
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a190019
activating transcription factor 69009
v-jun sarcoma virus 17 oncogene homolog (avian)9009
Histone H2A.x120012
thyroid hormone receptor beta isoform a7007
heat shock protein beta-18008
nuclear factor erythroid 2-related factor 2 isoform 1160016
lamin isoform A-delta10170017
Voltage-dependent calcium channel gamma-2 subunit120012
Glutamate receptor 2130013
Chain E, Purine nucleoside phosphorylase0101
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, ATP-DEPENDENT DNA HELICASE Q15005
Chain A, Ferritin light chain7007
Thymidine kinase 0101
thioredoxin reductase9009
phosphopantetheinyl transferase6006
GLS protein7007
TDP1 protein190019
Smad34004
thyroid stimulating hormone receptor6006
EWS/FLI fusion protein110012
arylsulfatase A3003
euchromatic histone-lysine N-methyltransferase 2130013
Bloom syndrome protein isoform 16006
hemoglobin subunit beta2002
atrial natriuretic peptide receptor 1 precursor2002
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Solute carrier family 22 member 1 0205
ATP-binding cassette sub-family C member 3010010
Multidrug resistance-associated protein 4010011
Solute carrier family 22 member 60001
Bile salt export pump0202
Bile salt export pump013013
Purine nucleoside phosphorylase0101
Thymidine kinase, cytosolic0001
POU domain, class 2, transcription factor 20001
Cytochrome P450 2C9 0404
Cytochrome P450 2J20303
Disintegrin and metalloproteinase domain-containing protein 172002
Purine nucleoside phosphorylase0011
Solute carrier family 22 member 60002
Thymidine kinase 0101
Solute carrier family 22 member 80002
Canalicular multispecific organic anion transporter 1010010
Thymidine kinase0101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE9009
Chain A, JmjC domain-containing histone demethylation protein 3A4004
Chain A, 2-oxoglutarate Oxygenase5005
Luciferase8008
endonuclease IV1001
15-lipoxygenase, partial4004
WRN1001
USP1 protein, partial8008
Microtubule-associated protein tau5006
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 3140014
cytochrome P450 family 3 subfamily A polypeptide 4110011
G6006
cytochrome P450 2D67007
peroxisome proliferator activated receptor gamma120012
aryl hydrocarbon receptor9009
thyroid stimulating hormone receptor100010
polyunsaturated fatty acid lipoxygenase ALOX124004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 14004
chromobox protein homolog 19009
nuclear factor erythroid 2-related factor 2 isoform 28009
potassium voltage-gated channel subfamily H member 2 isoform d4004
histone deacetylase 9 isoform 34004
importin subunit beta-1 isoform 14004
mitogen-activated protein kinase 16006
flap endonuclease 16006
serine/threonine-protein kinase PLK12002
snurportin-14004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 15005
tumor susceptibility gene 101 protein2002
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)6006
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
geminin150015
DNA polymerase kappa isoform 17007
Vpr2002
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 18008
histone acetyltransferase KAT2A isoform 16006
kelch-like ECH-associated protein 10002
Gamma-aminobutyric acid receptor subunit pi8008
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Interferon beta120012
HLA class I histocompatibility antigen, B alpha chain 6006
Transthyretin0101
Gag-Pol polyprotein0101
Cellular tumor antigen p53180018
Apoptosis regulator Bcl-20101
Gamma-aminobutyric acid receptor subunit beta-18008
Gamma-aminobutyric acid receptor subunit delta8008
Gamma-aminobutyric acid receptor subunit gamma-28008
D(3) dopamine receptor0101
Glutamate receptor 11001
Glutamate receptor 31001
Glutamate receptor 41001
Gamma-aminobutyric acid receptor subunit alpha-58008
Gamma-aminobutyric acid receptor subunit alpha-38008
Amine oxidase [flavin-containing] A0303
Gamma-aminobutyric acid receptor subunit gamma-18008
Gamma-aminobutyric acid receptor subunit alpha-28008
Amine oxidase [flavin-containing] B0303
Gamma-aminobutyric acid receptor subunit alpha-48008
Gamma-aminobutyric acid receptor subunit gamma-38008
Gamma-aminobutyric acid receptor subunit alpha-68008
Histamine H2 receptor4005
Gamma-aminobutyric acid receptor subunit alpha-18008
Gamma-aminobutyric acid receptor subunit beta-38008
Guanine nucleotide-binding protein G3003
Gamma-aminobutyric acid receptor subunit beta-28008
Inositol monophosphatase 13003
Induced myeloid leukemia cell differentiation protein Mcl-10101
TAR DNA-binding protein 438008
Cytochrome P450 1B10101
RmtA0101
Reverse transcriptase/RNaseH 0102
GABA theta subunit8008
Inositol hexakisphosphate kinase 16006
Protein arginine N-methyltransferase 10101
Gamma-aminobutyric acid receptor subunit epsilon8008
cytochrome P450 2C9, partial6006
phosphoglycerate kinase2002
acetylcholinesterase7007
NFKB1 protein, partial3003
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 46006
putative alpha-glucosidase1001
thyroid hormone receptor beta isoform 2170017
peripheral myelin protein 226006
Solute carrier family 22 member 20203
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0516
Spike glycoprotein100010
Glutamate receptor ionotropic, NMDA 2A 0415
Glutamate receptor ionotropic, NMDA 2B0415
Glutamate receptor ionotropic, NMDA 2C0415
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0415
Solute carrier family 22 member 10102
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0415
Multidrug and toxin extrusion protein 10303
Solute carrier family 22 member 20101
Glutamate receptor ionotropic, NMDA 3A0415
ATP-dependent phosphofructokinase6006
Chain A, Hyaluronidase, phage associated0101
thioredoxin glutathione reductase4004
glucocorticoid receptor [Homo sapiens]190019
estrogen-related nuclear receptor alpha180018
vitamin D (1,25- dihydroxyvitamin D3) receptor110011
IDH19009
lethal(3)malignant brain tumor-like protein 1 isoform I3003
lethal factor (plasmid)6006
Polyphenol oxidase 20101
Pancreatic alpha-amylase0202
Albumin0101
Urease0101
Prolyl 4-hydroxylase subunit alpha-10001
Tyrosinase0202
Alpha-2B adrenergic receptor0314
Hyaluronate lyase0101
Prolyl hydroxylase EGLN20001
Egl nine homolog 10113
Prolyl hydroxylase EGLN30001
Hypoxia-inducible factor 1-alpha inhibitor0102
Solute carrier family 23 member 10101
pregnane X nuclear receptor110011
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta3003
short transient receptor potential channel 6 isoform 10011
5-hydroxytryptamine receptor 40202
Muscarinic acetylcholine receptor M205210
Muscarinic acetylcholine receptor M40417
Muscarinic acetylcholine receptor M10418
Muscarinic acetylcholine receptor M30418
Muscarinic acetylcholine receptor M40418
Muscarinic acetylcholine receptor M50418
Muscarinic acetylcholine receptor M50518
Muscarinic acetylcholine receptor M20419
Muscarinic acetylcholine receptor M105311
Muscarinic acetylcholine receptor M10012
Muscarinic acetylcholine receptor M30417
Alpha-1D adrenergic receptor0617
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M40101
5-hydroxytryptamine receptor 70101
Muscarinic acetylcholine receptor0112
Cytochrome P450 3A40505
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Sodium- and chloride-dependent betaine transporter0101
Sodium- and chloride-dependent GABA transporter 30101
Proton-coupled amino acid transporter 10303
Sodium- and chloride-dependent GABA transporter 20101
caspase 7, apoptosis-related cysteine protease6006
caspase-36006
ATPase family AAA domain-containing protein 5110011
Ataxin-2110011
Pannexin-10101
Nuclear receptor ROR-gamma4004
Potassium channel subfamily K member 30303
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
progesterone receptor130013
nuclear receptor subfamily 1, group I, member 2110011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, Breast cancer type 1 susceptibility protein2002
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, Cruzipain3003
interleukin 82002
Nrf21001
pregnane X receptor2002
SMAD family member 27007
ATAD5 protein, partial5005
SMAD family member 37007
alkaline phosphatase, intestinal0101
apical membrane antigen 1, AMA12002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)7007
PINK12002
farnesoid X nuclear receptor8008
glucocerebrosidase2002
Parkin2002
bromodomain adjacent to zinc finger domain 2B3003
toll-like receptor 90101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
TPA: protein transporter TIM100101
thyrotropin-releasing hormone receptor4004
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
lysosomal alpha-glucosidase preproprotein2002
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0101
cellular tumor antigen p53 isoform a3003
perilipin-50101
vitamin D3 receptor isoform VDRA7007
intestinal alkaline phosphatase precursor0101
perilipin-10101
transcriptional regulator ERG isoform 33003
huntingtin isoform 23003
pyruvate kinase PKM isoform a1001
nuclear factor NF-kappa-B p105 subunit isoform 13003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
GTP-binding nuclear protein Ran isoform 12002
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
nuclear receptor ROR-gamma isoform 13003
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
muscleblind-like protein 1 isoform 13003
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
alkaline phosphatase, germ cell type preproprotein0101
caspase-1 isoform alpha precursor3003
hypothetical protein SA14220101
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
neuropeptide S receptor isoform A2002
Prostaglandin E synthase0101
Histone deacetylase 30101
Acetylcholinesterase0101
Lysine-specific histone demethylase 1A0101
D-amino-acid oxidase0101
Phospholipase A20101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Amyloid-beta precursor protein0102
Integrin beta-33003
Neuronal proto-oncogene tyrosine-protein kinase Src 0101
Prostaglandin G/H synthase 10101
Cholinesterase0101
Heme oxygenase 1 0101
Integrin alpha-IIb3003
Glutathione S-transferase P0101
Polyunsaturated fatty acid 5-lipoxygenase0101
60 kDa chaperonin0303
Replicase polyprotein 1ab0213
Replicase polyprotein 1ab0213
Microtubule-associated protein tau0102
60 kDa heat shock protein, mitochondrial0404
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Tissue factor0101
Aminopeptidase N0101
Aminopeptidase N0101
Alpha-1B adrenergic receptor0505
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20202
Glycogen synthase kinase-3 beta0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Acetylcholinesterase0202
Heme oxygenase 20101
Alpha-1D adrenergic receptor0404
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Proteasome subunit beta type-50101
Prostaglandin G/H synthase 20303
17-beta-hydroxysteroid dehydrogenase type 20101
Alpha-synuclein2114
Alpha-1A adrenergic receptor0606
Glycogen synthase kinase-3 beta0101
Caspase-73003
Histone deacetylase 40101
Beta-secretase 10101
10 kDa heat shock protein, mitochondrial0404
Cholinesterase0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
Serine/threonine-protein kinase PAK 10101
Histone deacetylase 10202
5-hydroxytryptamine receptor 40011
Sodium/bile acid cotransporter0011
Nuclear factor erythroid 2-related factor 20011
Thiosulfate sulfurtransferase0404
Thioredoxin reductase 1, cytoplasmic0101
60 kDa chaperonin 0404
10 kDa chaperonin 0404
Thioredoxin reductase 30101
Sortase A0101
Histone deacetylase 70101
Histone deacetylase 20202
CREB-binding protein0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30202
Cysteine protease 0101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
NACHT, LRR and PYD domains-containing protein 3 0101
Histone deacetylase 80202
Thioredoxin reductase 2, mitochondrial0101
CDGSH iron-sulfur domain-containing protein 10202
Histone deacetylase 60101
Histone deacetylase 90101
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Histone deacetylase 50101
Lymphocyte antigen 960011
Beta lactamase (plasmid)0101
Glucose transporter0101
Cdk-related protein kinase 60101
Protein kinase domain-containing protein0101
Hexose transporter 1 0101
Solute carrier family 2, facilitated glucose transporter member 10101
Deoxycytidine kinase0001
Cytidine deaminase0001
Calcium-dependent protein kinase 10101
Mitogen-activated protein kinase 0101
Proline--tRNA ligase0101
Calcium-dependent protein kinase 40101
Lysine--tRNA ligase 0101
Uridine-cytidine kinase 1 0001
Chain A, Beta-lactamase4004
Genome polyprotein 0112
chaperonin-containing TCP-1 beta subunit homolog1001
Fumarate hydratase2002
hypothetical protein, conserved3003
polyprotein2002
eyes absent homolog 2 isoform a1001
relaxin receptor 1 isoform 11001
Flavin reductase (NADPH)0011
large T antigen0101
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Prolyl 4-hydroxylase0202
Prolyl 3-hydroxylase OGFOD10101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Multidrug resistance-associated protein 1 0002
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor06112
Glycine receptor subunit alpha-10606
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Androgen receptor0505
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Nuclear receptor subfamily 1 group I member 20011
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
67.9K protein3003
luciferase1001
Caspase-72002
tumor necrosis factor2002
caspase-32002
Epidermal growth factor receptor0101
Tyrosine-protein kinase Fyn0101
Alpha-2A adrenergic receptor0516
Adenosine receptor A30202
Cytochrome P450 2D60101
D(2) dopamine receptor0303
Alpha-2C adrenergic receptor0415
Substance-K receptor0202
D(1A) dopamine receptor0202
Glutamate receptor ionotropic, kainate 11001
Histamine H2 receptor0202
5-hydroxytryptamine receptor 2A0202
Adenosine receptor A2a0202
Mu-type opioid receptor0202
D(3) dopamine receptor0303
Kappa-type opioid receptor0202
Glutamate receptor ionotropic, kainate 21001
Glutamate receptor ionotropic, kainate 31001
Fatty-acid amide hydrolase 11001
Glutamate receptor ionotropic, kainate 41001
Sodium-dependent dopamine transporter 0202
Leukotriene B4 receptor 11001
Glutamate receptor ionotropic, kainate 51001
Leukotriene B4 receptor 21001
Rho-associated protein kinase 20303
Rho-associated protein kinase 10303
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E0011
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10101
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Carbonic anhydrase 10101
Carbonic anhydrase 20112
Carbonic anhydrase 40101
Carbonic anhydrase0101
Carbonic anhydrase 150101
muscarinic acetylcholine receptor M11001
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Potassium voltage-gated channel subfamily H member 20405
Sodium channel protein type 5 subunit alpha0202
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0101
PPM1D protein3003
retinoic acid receptor alpha isoform 10101
retinoic acid receptor RXR-alpha isoform a0101
Dihydrofolate reductase0304
Dipeptidyl peptidase 40101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
dopamine D1 receptor3003
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase1001
Thymidylate synthase 0101
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0202
M-phase phosphoprotein 81001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40202
Indoleamine 2,3-dioxygenase 10101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
DNA gyrase subunit B0101
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA topoisomerase 4 subunit A0101
DNA gyrase subunit B0101
DNA topoisomerase 2-alpha0001
Potassium voltage-gated channel subfamily E member 10101
DNA gyrase subunit A0101
Potassium voltage-gated channel subfamily KQT member 10101
DNA gyrase subunit B0102
DNA gyrase subunit A0102
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
glp-1 receptor, partial4004
Alpha-1B adrenergic receptor 0011
D(1A) dopamine receptor1001
ras-related protein Rab-9A1001
Beta-2 adrenergic receptor0011
Beta-1 adrenergic receptor0011
Beta-3 adrenergic receptor0011
POU domain, class 2, transcription factor 10001
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0213
Alpha-1B adrenergic receptor0202
Alpha-2B adrenergic receptor0314
Alpha-2C adrenergic receptor0213
Alpha-2A adrenergic receptor0213
Alpha-2B adrenergic receptor0001
Alpha-1A adrenergic receptor0336
Alpha-1B adrenergic receptor0336
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
luciferase0001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
Riboflavin-binding protein0112
photoreceptor-specific nuclear receptor0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
ATP-dependent translocase ABCB10101
Insulin receptor 0101
Nuclear receptor subfamily 4 group A member 20011
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase0101
Sigma non-opioid intracellular receptor 10101
Solute carrier organic anion transporter family member 1B10101
isocitrate dehydrogenase 1, partial1001
nonstructural protein 10101
protein AF-9 isoform a0001
Alpha-1A adrenergic receptor0112
5-hydroxytryptamine receptor 1A0101
Tryptophan 5-hydroxylase 10101
Sodium-dependent dopamine transporter0101
5-hydroxytryptamine receptor 70101
Alpha-1D adrenergic receptor0101
Alpha-1B adrenergic receptor0101
Alpha-1A adrenergic receptor0101
peripheral myelin protein 22 isoform 11001
procathepsin L isoform 1 preproprotein0101
Albumin0011
Sodium-dependent serotonin transporter0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
Sterol 14-alpha-demethylase0011
14-alpha sterol demethylase 0011
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Lanosterol 14-alpha demethylase0011
Cytochrome P450 2B60101
Cytochrome P450 2C190101
Cytochrome P450 1440011
Steroid C26-monooxygenase0011
Steroid C26-monooxygenase0011
Sterol 14-alpha demethylase0011
14-alpha sterol demethylase 0011
14-alpha sterol demethylase 0011
Cholesterol 24-hydroxylase0213
Chain E, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor, alpha form0101
Chain B, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, Rho-associated protein kinase 10101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit0101
Chain I, cAMP-dependent protein kinase inhibitor alpha0101
Chain A, Rho-associated protein kinase 10101
Ribosomal protein S6 kinase alpha-50101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit alpha 0101
C-C motif chemokine 20101
cAMP-dependent protein kinase catalytic subunit alpha0101
cAMP-dependent protein kinase catalytic subunit gamma0101
cAMP-dependent protein kinase catalytic subunit beta0101
Serine/threonine-protein kinase N20101
Rho-associated protein kinase 20101
Rho-associated protein kinase 20101
streptokinase A precursor0011
twin arginine protein translocation system - TatA protein0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]