Page last updated: 2024-09-28

Congenital Poikiloderma

An autosomal recessive syndrome occurring principally in females, characterized by the presence of reticulated, atrophic, hyperpigmented, telangiectatic cutaneous plaques, often accompanied by juvenile cataracts, saddle nose, congenital bone defects, disturbances in the growth of HAIR; NAILS; and TEETH; and HYPOGONADISM.

Synonyms(6)

Synonym
Congenital Poikiloderma
Poikiloderma of Rothmund-Thomson
Poikiloderma Congenitale
Poikiloderma Congenitale of Rothmund-Thomson
Poikiloderma Atrophicans and Cataract
Rothmund-Thomson Syndrome

Research

Studies (50)

TimeframeStudies, This Condition (%)All Conditions %
pre-199021 (42.00)23.3326
1990's5 (10.00)12.5806
2000's13 (26.00)18.1394
2010's9 (18.00)28.8240
2020's2 (4.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
cytosine0low10
glycine0low10
iodine0low10
kynurenine0low10
nickel0low10
niacin0low20
thymine0low20
betaxolol0low10
cyproheptadine0low10
hydroxyurea0low20
2-propanol0low20
methyl methanesulfonate0low10
mitomycin0low10
hydroxyproline0low10
serine0low10
4-nitroquinoline-1-oxide0low10
glutamine0low10
levodopa0low10
tryptophan0low10
arginine0low20
pantothenic acid0low10
6-methylcoumarin0low10
diepoxybutane0low10
thymine glycol0low10
thorium0low10
xenon0low10
camptothecin0low10
fomesafen0low10
methotrexate0low20
sb 2035800low10
inositol 3-phosphate0low10
aphidicolin0low10
bromochloroacetic acid0low20
etretinate0low10
oxadiazoles0low10
nad0low10
oligonucleotides0low10
piperidines0low10
warfarin0low10
exudates0low10
guanine0low20
8-hydroxyguanine0low10
eye0low10

Protein Targets (910)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit6006
RAR-related orphan receptor gamma8008
GLI family zinc finger 38008
AR protein120012
aldehyde dehydrogenase 1 family, member A19009
retinoic acid nuclear receptor alpha variant 1130013
retinoid X nuclear receptor alpha7007
estrogen nuclear receptor alpha140014
peroxisome proliferator-activated receptor delta5005
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x6006
thyroid hormone receptor beta isoform a3003
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 19009
lamin isoform A-delta107007
Voltage-dependent calcium channel gamma-2 subunit7007
Glutamate receptor 27007
nuclear receptor subfamily 1, group I, member 36006
glucocorticoid receptor [Homo sapiens]8008
farnesoid X nuclear receptor6006
pregnane X nuclear receptor7007
vitamin D (1,25- dihydroxyvitamin D3) receptor8008
IDH14004
aryl hydrocarbon receptor6006
chromobox protein homolog 16006
geminin8008
Rap guanine nucleotide exchange factor 32002
Nuclear receptor ROR-gamma2002
TAR DNA-binding protein 433003
Microtubule-associated protein tau4004
Olfactory receptor 51E20022
Chain A, caspase-3, p17 subunit0101
Chain B, caspase-3, p12 subunit0101
Chain A, caspase-3, p17 subunit0101
Chain B, caspase-3, p12 subunit0101
Chain A, caspase-3, p17 subunit0101
Chain B, caspase-3, p12 subunit0101
Caspase-10202
Caspase-30202
Caspase-20101
Caspase-71102
Caspase-60101
Caspase-80101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE7007
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
TDP1 protein8008
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
euchromatic histone-lysine N-methyltransferase 29009
huntingtin isoform 23003
survival motor neuron protein isoform d3003
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase beta0101
DNA polymerase beta0101
DNA polymerase catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase alpha catalytic subunit0112
DNA polymerase delta catalytic subunit0101
DNA polymerase catalytic subunit0101
DNA polymerase subunit gamma-10101
DNA polymerase lambda0101
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
thioredoxin reductase8008
phosphopantetheinyl transferase7007
NFKB1 protein, partial3003
GLS protein5005
thyroid stimulating hormone receptor7007
alpha-galactosidase3003
cytochrome P450 2C19 precursor4004
flap endonuclease 15005
DNA polymerase iota isoform a (long)7007
muscarinic acetylcholine receptor M14004
lethal factor (plasmid)5005
Cytochrome P450 3A40102
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase6006
cytochrome P450 family 3 subfamily A polypeptide 44004
EWS/FLI fusion protein100010
cytochrome P450 2D65005
Beta-1 adrenergic receptor 0011
arylsulfatase A4004
hexokinase-4 isoform 12002
thyroid hormone receptor beta isoform 28008
glucokinase regulatory protein2002
Gamma-aminobutyric acid receptor subunit pi3014
Bile salt export pump0808
Beta-1 adrenergic receptor0112
Cytochrome P450 2D60202
Gamma-aminobutyric acid receptor subunit beta-13014
Beta-1 adrenergic receptor0011
Gamma-aminobutyric acid receptor subunit delta3014
Gamma-aminobutyric acid receptor subunit gamma-23014
5-hydroxytryptamine receptor 1A0213
Gamma-aminobutyric acid receptor subunit alpha-53014
Gamma-aminobutyric acid receptor subunit alpha-33014
Gamma-aminobutyric acid receptor subunit gamma-13014
Gamma-aminobutyric acid receptor subunit alpha-23014
Gamma-aminobutyric acid receptor subunit alpha-43014
Gamma-aminobutyric acid receptor subunit gamma-33014
Gamma-aminobutyric acid receptor subunit alpha-63014
Gamma-aminobutyric acid receptor subunit alpha-13014
Gamma-aminobutyric acid receptor subunit beta-33014
Gamma-aminobutyric acid receptor subunit beta-23014
Beta-2 adrenergic receptor 0011
Beta-2 adrenergic receptor0011
GABA theta subunit3014
Gamma-aminobutyric acid receptor subunit epsilon3014
thyroid stimulating hormone receptor3003
Cellular tumor antigen p538008
Chain A, HADH2 protein6006
Chain B, HADH2 protein6006
Chain A, 2-oxoglutarate Oxygenase8008
Chain A, Ferritin light chain2002
Chain A, Cruzipain1001
DNA topoisomerase 0101
15-lipoxygenase, partial5005
ATAD5 protein, partial4004
Fumarate hydratase5005
PPM1D protein4004
Thrombopoietin1001
regulator of G-protein signaling 43003
estrogen-related nuclear receptor alpha130013
polyprotein5005
67.9K protein4004
glucocerebrosidase1001
putative alpha-glucosidase1001
Bloom syndrome protein isoform 16006
lysosomal alpha-glucosidase preproprotein2002
peripheral myelin protein 22 isoform 14004
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a3003
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
nuclear factor erythroid 2-related factor 2 isoform 24004
ras-related protein Rab-9A1001
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor0011
serine/threonine-protein kinase mTOR isoform 12002
nuclear receptor ROR-gamma isoform 12002
cytochrome P450 3A4 isoform 13003
M-phase phosphoprotein 84004
muscleblind-like protein 1 isoform 12002
histone acetyltransferase KAT2A isoform 13003
relaxin receptor 1 isoform 11001
Telomerase reverse transcriptase0101
Serine/threonine-protein kinase Chk10022
Histone deacetylase 30101
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40506
Type-2 restriction enzyme ScaI0101
Deoxyribonuclease-2-alpha0101
Tyrosyl-DNA phosphodiesterase 20101
Deoxyribonuclease-10101
Type-2 restriction enzyme PstI0101
Type-2 restriction enzyme EcoRI0101
Prothrombin0001
DNA ligase0101
Interferon beta5005
Integrin beta-32002
Integrin alpha-IIb2002
Heterogeneous nuclear ribonucleoprotein A10011
DNA topoisomerase 10116
DNA topoisomerase 2-alpha0101
Type-2 restriction enzyme BamHI0101
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
5-hydroxytryptamine receptor 2B0404
Type-2 restriction enzyme HindIII0101
D(1A) dopamine receptor1001
Histone deacetylase 40101
Ribonuclease pancreatic0101
Inositol monophosphatase 12002
DNA topoisomerase 2-beta0001
DNA topoisomerase 10102
Histone deacetylase 10101
DNA topoisomerase 10101
Integrase 0101
Histone deacetylase 70101
Histone deacetylase 20101
Canalicular multispecific organic anion transporter 10505
DNA topoisomerase type IB small subunit 0011
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
Histone deacetylase 80101
Tyrosyl-DNA phosphodiesterase 10101
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
cytochrome P450 2D6 isoform 12002
D(1A) dopamine receptor1001
potassium voltage-gated channel subfamily H member 2 isoform d1001
atrial natriuretic peptide receptor 2 precursor1001
peripheral myelin protein 224004
chaperonin GroEL1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 40202
Prostaglandin G/H synthase 10101
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
5-hydroxytryptamine receptor 2C0203
Muscarinic acetylcholine receptor M50101
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Muscarinic acetylcholine receptor M20101
Glycogen phosphorylase, brain form0101
Glycogen phosphorylase, muscle form0101
Muscarinic acetylcholine receptor M10404
Angiotensin-converting enzyme0202
D(2) dopamine receptor0202
5-hydroxytryptamine receptor 2A0303
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
D0101
D(3) dopamine receptor0101
Muscarinic acetylcholine receptor M30202
Endothelin receptor type B0101
D(1A) dopamine receptor0202
UDP-glucuronosyltransferase 1A40001
Sodium-dependent noradrenaline transporter 0202
Endothelin receptor type B0101
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0202
D(4) dopamine receptor0101
5-hydroxytryptamine receptor 2B0101
Sodium-dependent serotonin transporter0101
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 70101
Histamine H1 receptor0213
D(3) dopamine receptor0202
UDP-glucuronosyltransferase 1A30001
Histamine H2 receptor2002
5-hydroxytryptamine receptor 60202
Spike glycoprotein4004
D(2) dopamine receptor0101
D(2) dopamine receptor0202
Potassium voltage-gated channel subfamily H member 20202
Sodium-dependent serotonin transporter0101
Nuclear receptor subfamily 3 group C member 3 0202
Histone-lysine N-methyltransferase SETD70202
Ataxin-23003
Transporter0101
Deoxycytidine kinase0001
Chain A, Beta-lactamase2002
Chain A, JmjC domain-containing histone demethylation protein 3A3003
acetylcholinesterase3003
glp-1 receptor, partial2002
SMAD family member 22002
SMAD family member 32002
thioredoxin glutathione reductase2002
Smad31001
apical membrane antigen 1, AMA12002
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)4004
progesterone receptor7007
peroxisome proliferator activated receptor gamma8008
caspase-32002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Vpr1001
Glutathione S-transferase omega-10101
ATPase family AAA domain-containing protein 52002
USP1 protein, partial3003
G2002
HLA class I histocompatibility antigen, B alpha chain 2002
Inositol hexakisphosphate kinase 12002
cytochrome P450 2C9, partial2002
Luciferase3003
Chain A, Glutamine Binding Protein0011
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Carbonic anhydrase 10003
Carbonic anhydrase 20116
Neutral amino acid transporter A0303
Asc-type amino acid transporter 10202
Neutral amino acid transporter B(0)0303
Carbonic anhydrase-like protein, putative0003
Amino acid transporter0303
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Glutamate receptor ionotropic, NMDA 1 0215
Sodium- and chloride-dependent glycine transporter 10101
Glutamate receptor ionotropic, NMDA 2A 0215
Glutamate receptor ionotropic, NMDA 2B0215
Glutamate receptor ionotropic, NMDA 2C0215
Large neutral amino acids transporter small subunit 10303
Glutamate receptor ionotropic, NMDA 2D0215
Proton-coupled amino acid transporter 10303
Glutamate receptor ionotropic, NMDA 3B0215
Serine racemase0101
Glutamate receptor ionotropic, NMDA 3A0215
Sodium- and chloride-dependent glycine transporter 20101
Purine nucleoside phosphorylase0202
Hypoxanthine-guanine phosphoribosyltransferase0001
Ricin0101
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase0011
Purine nucleoside phosphorylase 0012
Shiga toxin subunit A0101
Guanine deaminase0001
vitamin D3 receptor isoform VDRA3003
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Stromelysin-10112
Gamma-aminobutyric acid receptor subunit alpha-10101
Urease subunit alpha0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Carbonic anhydrase 40103
Ribonucleoside-diphosphate reductase large subunit0101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Carbonic anhydrase 5A, mitochondrial0103
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Urease subunit beta0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Carbonic anhydrase 90104
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
histone deacetylase 9 isoform 31001
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
dopamine D1 receptor2002
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
atrial natriuretic peptide receptor 1 precursor1001
importin subunit beta-1 isoform 12002
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
snurportin-12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
DNA polymerase kappa isoform 14004
Polyphenol oxidase 20102
Carbonic anhydrase 120002
Epidermal growth factor receptor0213
Plasma kallikrein0002
Tyrosine-protein kinase Lck0213
Tyrosine-protein kinase Fyn0112
Carbonic anhydrase 30002
Polyunsaturated fatty acid lipoxygenase ALOX150101
Tyrosinase0101
Carbonic anhydrase 60002
Adenosine receptor A10001
Adenosine receptor A2a0001
Carbonic anhydrase0002
Carbonic anhydrase 70002
Solute carrier family 15 member 10101
Carbonic anhydrase0002
SLC16A10 protein0002
Carbonic anhydrase 0002
Carbonic anhydrase0002
Carbonic anhydrase0002
Carbonic anhydrase 0002
Monocarboxylate transporter 100002
Carbonic anhydrase 150002
Carbonic anhydrase 130002
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
phosphoglycerate kinase1001
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
transcriptional regulator ERG isoform 31001
DNA polymerase beta1001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0405
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10022
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20022
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0101
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
Disintegrin and metalloproteinase domain-containing protein 171001
nuclear receptor subfamily 1, group I, member 21001
Indoleamine 2,3-dioxygenase 10203
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
bromodomain adjacent to zinc finger domain 2B2002
thyrotropin-releasing hormone receptor1001
Amyloid-beta precursor protein0101
Neuronal acetylcholine receptor subunit alpha-41102
Cholesteryl ester transfer protein0202
Cytochrome P450 2C9 0314
Neuronal acetylcholine receptor subunit beta-21102
D-amino-acid oxidase0101
Xanthine dehydrogenase/oxidase0101
Hydroxycarboxylic acid receptor 30011
Nicotinamidase0101
Hydroxycarboxylic acid receptor 20011
Hydroxycarboxylic acid receptor 20213
Multidrug and toxin extrusion protein 10101
D-aspartate oxidase0101
Hydroxycarboxylic acid receptor 20112
Type II pantothenate kinase0001
Type III pantothenate kinase0001
Chain A, Erk20101
Leukotriene C4 synthase0011
cytochrome P450 2C9 precursor1001
mitogen-activated protein kinase 11001
tyrosine-protein kinase Yes1001
Bone morphogenetic protein receptor type-1B0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0011
Serine/threonine-protein kinase PLK40011
Serine/threonine-protein kinase 250011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0011
Citron Rho-interacting kinase0112
Serine/threonine-protein kinase RIO30011
Dual specificity mitogen-activated protein kinase kinase 70011
Inhibitor of nuclear factor kappa-B kinase subunit beta0011
Peripheral plasma membrane protein CASK0011
Aurora kinase A0011
Cyclin-G-associated kinase0112
Serine/threonine-protein kinase DCLK10011
Inhibitor of nuclear factor kappa-B kinase subunit alpha0011
Muscle, skeletal receptor tyrosine-protein kinase0011
Ephrin type-B receptor 60011
Mitogen-activated protein kinase 130123
3-phosphoinositide-dependent protein kinase 10011
Mitogen-activated protein kinase 20101
Mitogen-activated protein kinase kinase kinase 130011
Death-associated protein kinase 30011
Mitogen-activated protein kinase kinase kinase 70011
Receptor-interacting serine/threonine-protein kinase 20112
NUAK family SNF1-like kinase 10011
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0011
Tyrosine-protein kinase JAK20011
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0011
Serine/threonine-protein kinase PAK 30011
Cyclin-dependent kinase-like 50011
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Serine/threonine-protein kinase 17B0011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30112
Cyclin-dependent kinase 140011
Mitogen-activated protein kinase kinase kinase 60011
Serine/threonine-protein kinase OSR10011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Serine/threonine-protein kinase Chk20011
RAF proto-oncogene serine/threonine-protein kinase0112
Receptor tyrosine-protein kinase erbB-20112
High affinity nerve growth factor receptor0011
Protein kinase C gamma type0101
Myeloperoxidase0202
Cytochrome P450 1A20101
Protein kinase C beta type0101
Insulin receptor0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0011
Tyrosine-protein kinase Yes0011
Tyrosine-protein kinase Lyn0011
Proto-oncogene tyrosine-protein kinase receptor Ret0011
Insulin-like growth factor 1 receptor0011
Neutrophil elastase0101
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0011
Proto-oncogene tyrosine-protein kinase ROS0011
Platelet-derived growth factor receptor beta0011
Tyrosine-protein kinase Fgr0011
Wee1-like protein kinase 20011
Uncharacterized serine/threonine-protein kinase SBK30011
Mast/stem cell growth factor receptor Kit0011
Serine/threonine-protein kinase pim-10011
Tyrosinase0101
Fibroblast growth factor receptor 10011
Myosin light chain kinase, smooth muscle0011
Cyclin-dependent kinase 40011
Proto-oncogene tyrosine-protein kinase Src0112
Insulin receptor-related protein0011
Serine/threonine-protein kinase B-raf0112
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Platelet-derived growth factor receptor alpha0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0101
cAMP-dependent protein kinase catalytic subunit alpha0112
Vascular endothelial growth factor receptor 1 0011
Interferon-induced, double-stranded RNA-activated protein kinase0011
Amine oxidase [flavin-containing] B0101
Casein kinase II subunit alpha'0011
Serine/threonine-protein kinase MAK0011
Cyclin-dependent kinase 11B0011
Ephrin type-A receptor 10011
Fibroblast growth factor receptor 20011
Receptor tyrosine-protein kinase erbB-30011
Fibroblast growth factor receptor 40011
Fibroblast growth factor receptor 30011
cAMP-dependent protein kinase catalytic subunit gamma0101
cAMP-dependent protein kinase catalytic subunit beta0112
Prostaglandin G/H synthase 10101
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10011
Thromboxane-A synthase 0101
Protein kinase C eta type0112
Activin receptor type-2A0011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Adenosine receptor A2a0202
Ephrin type-A receptor 20011
Ephrin type-A receptor 30011
Ephrin type-A receptor 80011
Ephrin type-B receptor 20112
Leukocyte tyrosine kinase receptor0011
Non-receptor tyrosine-protein kinase TYK20011
Wee1-like protein kinase0011
Tyrosine-protein kinase receptor UFO0011
Adenosine receptor A10202
Mitogen-activated protein kinase 40011
Sodium-dependent serotonin transporter0101
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
G protein-coupled receptor kinase 40011
Delta-type opioid receptor0101
Cytochrome P450 2C190101
Dual specificity protein kinase TTK0011
Prostaglandin G/H synthase 20011
Tyrosine-protein kinase receptor Tie-10011
Vascular endothelial growth factor receptor 30011
Vascular endothelial growth factor receptor 20011
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30011
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10112
Serine/threonine-protein kinase receptor R30011
TGF-beta receptor type-20011
Tyrosine-protein kinase CSK0011
Protein kinase C iota type0112
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0011
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0011
Serine/threonine-protein kinase mTOR0011
Megakaryocyte-associated tyrosine-protein kinase0011
Tyrosine-protein kinase Tec0011
Tyrosine-protein kinase TXK0011
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0011
Tyrosine-protein kinase ZAP-700011
Tyrosine-protein kinase SYK0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90112
Dual specificity mitogen-activated protein kinase kinase 40011
Dual specificity mitogen-activated protein kinase kinase 30011
Mitogen-activated protein kinase 14 0112
Casein kinase I isoform alpha0011
Casein kinase I isoform delta0112
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0011
MAP kinase-activated protein kinase 20011
Cyclin-dependent kinase 80011
Casein kinase I isoform epsilon0112
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Dual specificity protein kinase CLK30011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Tyrosine-protein kinase Blk0011
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0011
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Serine/threonine-protein kinase Nek40011
Tyrosine-protein kinase JAK30011
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
Death-associated protein kinase 10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 120123
Mitogen-activated protein kinase 100213
5'-AMP-activated protein kinase catalytic subunit alpha-20011
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-B receptor 10011
Ephrin type-A receptor 40011
Hormonally up-regulated neu tumor-associated kinase0011
Serine/threonine-protein kinase SIK10011
Receptor-interacting serine/threonine-protein kinase 40011
Cell division control protein 2 homolog0011
Calcium-dependent protein kinase 10011
Mitogen-activated protein kinase 10101
Tubulin alpha-1A chain0011
Casein kinase II subunit alpha0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0011
SRSF protein kinase 20011
Casein kinase I isoform gamma-20011
Mitogen-activated protein kinase kinase kinase 90011
Serine/threonine-protein kinase PknB0011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase-like 10011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
Protein kinase C epsilon type0112
Dual specificity mitogen-activated protein kinase kinase 10112
Angiopoietin-1 receptor0112
Mitogen-activated protein kinase kinase kinase 100011
Protein kinase C theta type0112
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C zeta type0101
Protein kinase C delta type0112
Tyrosine-protein kinase BTK0011
Tyrosine-protein kinase receptor TYRO30011
Cyclin-dependent kinase 180011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0011
Myotonin-protein kinase0112
Mitogen-activated protein kinase kinase kinase kinase 20011
Mitogen-activated protein kinase kinase kinase 120011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10011
Serine/threonine-protein kinase PAK 10011
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
cGMP-dependent protein kinase 20011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Serine/threonine-protein kinase PRP4 homolog0011
Receptor-interacting serine/threonine-protein kinase 10011
Calcium/calmodulin-dependent protein kinase type II subunit beta0011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60011
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Calcium/calmodulin-dependent protein kinase type 10011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Serine/threonine-protein kinase D10112
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40011
Ribosomal protein S6 kinase alpha-20011
Ephrin type-A receptor 70011
Ribosomal protein S6 kinase alpha-10011
Dual specificity testis-specific protein kinase 10011
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110123
Serine/threonine-protein kinase STK110011
Rhodopsin kinase GRK10011
NT-3 growth factor receptor0011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140224
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
BDNF/NT-3 growth factors receptor0011
Mitogen-activated protein kinase 60011
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Serine/threonine-protein kinase SBK10011
Mitogen-activated protein kinase kinase kinase 190011
Serine/threonine-protein kinase TNNI3K0011
Leucine-rich repeat serine/threonine-protein kinase 20011
Serine/threonine-protein kinase MRCK alpha0011
P2X purinoceptor 70101
Serine/threonine-protein kinase MRCK gamma0011
Serine/threonine-protein kinase Nek50011
Serine/threonine-protein kinase ULK30011
Dual serine/threonine and tyrosine protein kinase0011
Mitogen-activated protein kinase kinase kinase 150011
Serine/threonine-protein kinase MARK20011
Serine/threonine-protein kinase TAO10011
Serine/threonine-protein kinase tousled-like 20011
Serine/threonine-protein kinase 32C0011
Serine/threonine-protein kinase pim-30011
Serine/threonine-protein kinase VRK20011
Myosin light chain kinase family member 40011
Homeodomain-interacting protein kinase 10011
Calcium/calmodulin-dependent protein kinase type 1D0011
Mitogen-activated protein kinase kinase kinase kinase 30011
Cyclin-dependent kinase-like 30011
MAP kinase-activated protein kinase 50011
Serine/threonine-protein kinase BRSK20011
Serine/threonine-protein kinase NIM10011
Serine/threonine-protein kinase ULK20011
Misshapen-like kinase 10011
Serine/threonine-protein kinase DCLK20011
Calcium/calmodulin-dependent protein kinase kinase 10011
Casein kinase I isoform alpha-like0011
Homeodomain-interacting protein kinase 40011
Myosin-IIIa0011
Ankyrin repeat and protein kinase domain-containing protein 10011
Serine/threonine-protein kinase Nek110011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase BRSK10011
Serine/threonine-protein kinase 350011
Serine/threonine-protein kinase Nek70011
Rhodopsin kinase GRK70011
Serine/threonine-protein kinase 32A0011
Myosin-IIIb0011
Dual specificity tyrosine-phosphorylation-regulated kinase 20011
Cyclin-dependent kinase-like 20011
Mitogen-activated protein kinase kinase kinase kinase 10011
Serine/threonine-protein kinase Sgk30011
Atypical kinase COQ8B, mitochondrial0011
Aurora kinase B0011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
Cyclin-dependent kinase 150011
Calcium/calmodulin-dependent protein kinase kinase 20011
SRSF protein kinase 10011
P2X purinoceptor 70101
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Serine/threonine-protein kinase RIO10011
MAP kinase-interacting serine/threonine-protein kinase 10011
Serine/threonine-protein kinase RIO20011
Cyclin-dependent kinase 190011
Transient receptor potential cation channel subfamily M member 60011
Testis-specific serine/threonine-protein kinase 10011
Serine/threonine-protein kinase 330011
Serine/threonine-protein kinase D20011
Serine/threonine-protein kinase DCLK30011
NUAK family SNF1-like kinase 20011
Serine/threonine-protein kinase SIK20011
Myosin light chain kinase 2, skeletal/cardiac muscle0011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
Homeodomain-interacting protein kinase 20011
Tyrosine-protein kinase Srms0011
Homeodomain-interacting protein kinase 30011
Serine/threonine-protein kinase PLK30011
Dual specificity protein kinase CLK40011
MAP kinase-interacting serine/threonine-protein kinase 20011
Serine/threonine-protein kinase Nek60011
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
SNF-related serine/threonine-protein kinase0011
Serine/threonine-protein kinase LATS20011
Serine/threonine-protein kinase 360112
BMP-2-inducible protein kinase0011
Interleukin-1 receptor-associated kinase 40011
Serine/threonine-protein kinase 32B0011
Mitogen-activated protein kinase kinase kinase 200011
Serine/threonine-protein kinase PLK20011
Serine/threonine-protein kinase MARK10011
Serine/threonine-protein kinase pim-20011
Serine/threonine-protein kinase PAK 50011
Serine/threonine-protein kinase 260011
eIF-2-alpha kinase GCN20011
Serine/threonine-protein kinase NLK0112
Phosphatidylinositol 4-kinase beta0011
Serine/threonine-protein kinase 17A0011
STE20/SPS1-related proline-alanine-rich protein kinase0011
Ephrin type-A receptor 60011
Serine/threonine-protein kinase TBK10011
Death-associated protein kinase 20011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0112
Serine/threonine-protein kinase tousled-like 10011
Serine/threonine-protein kinase TAO20011
ALK tyrosine kinase receptor0011
SRSF protein kinase 30011
Serine/threonine-protein kinase ICK0011
Cyclin-dependent kinase 11A0011
Aurora kinase C0011
Calcium/calmodulin-dependent protein kinase type II subunit alpha0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase 38-like0011
Microtubule-associated serine/threonine-protein kinase 10011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Acetylcholinesterase0101
Pyruvate kinase PKM0011
Cholinesterase0101
Thymidine phosphorylase0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Phospholipase A-2-activating protein0101
Albumin0011
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]