Page last updated: 2024-09-27

Congenital Hyperinsulinism

A familial, nontransient HYPOGLYCEMIA with defects in negative feedback of GLUCOSE-regulated INSULIN release. Clinical phenotypes include HYPOGLYCEMIA; HYPERINSULINEMIA; SEIZURES; COMA; and often large BIRTH WEIGHT. Several sub-types exist with the most common, type 1, associated with mutations on an ATP-BINDING CASSETTE TRANSPORTERS (subfamily C, member 8).

Synonyms(1)

Synonym
Congenital Hyperinsulinism

Research Excerpts

Overview

ExcerptReference
"Congenital hyperinsulinism is a rare pancreatic endocrine cell disorder that has been categorized histologically into diffuse and focal forms."( Adzick, NS; Ganguly, A; MacMullen, CM; Ruchelli, ED; Stanley, CA; Suchi, M; Thornton, PS, 2006)
"Congenital hyperinsulinism is a condition of dysregulated insulin secretion often caused by inactivating mutations of the ATP-sensitive K+ (KATP) channel in the pancreatic beta cell."( Becker, S; Ganguly, A; Hanna, C; Lin, YW; MacMullen, C; Pinney, SE; Shyng, SL; Stanley, CA; Thornton, P, 2008)
"Congenital hyperinsulinism is the most common cause of persistent hypoglycemia in infancy (HI), leading to severe neurologic disabilities if not promptly treated."( Chiumello, G; Di Candia, S; Gessi, A; Gianolli, L; Mangano, E; Mora, S; Pepe, G; Proverbio, MC; Sogno Valin, P, 2009)
"Congenital hyperinsulinism is a leading cause of severe hypoglycaemia in the newborn period."( Hussain, K; Ismail, D, 2010)
"Congenital hyperinsulinism is a genetic condition causing dysregulation of insulin and results in persistent hypoglycemia."( Edwards, TM; Spatz, DL, 2014)
"Congenital hyperinsulinism is a rare disorder that commonly presents in the immediate postnatal period as persistent hypoglycemia."( Chu, A; Minakova, E, 2017)
"Congenital hyperinsulinism is characterized by abnormal regulation of insulin secretion from the pancreas causing profound hypoketotic hypoglycemia and is the leading cause of persistent hypoglycemia in infants and children."( Garg, PK; Garg, S; Lokitz, SJ; Nazih, R; Nedrelow, JK; Putegnat, B; Reynolds, C; Sanchez, I; Thornton, PS; Truong, L; Uffman, J, 2020)
"Congenital hyperinsulinism is characterised by the inappropriate release of insulin during hypoglycaemia."( Flanagan, SE; Hewat, TI; Johnson, MB, 2022)
"Congenital hyperinsulinism is the most common cause of persistent hypoglycemia in neonates, infants, and children."( De Leon, DD; Stanley, CA; Thornton, PS, 2022)
"Congenital hyperinsulinism is the most common cause of persistent hypoglycemia in neonates, infants, and children."( De Leon, DD; Stanley, CA; Thornton, PS, 2022)

Research

Studies (271)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's56 (20.66)18.1394
2010's142 (52.40)28.8240
2020's73 (26.94)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carnitine0low10
3-hydroxybutyric acid0low30
creatine0low10
glycine0low10
glycolic acid0low10
dihydroxyphenylalanine0medium371
carbamazepine0low10
chlorothiazide0low20
diazoxide0medium1162
valproic acid0low10
fentanyl0low10
fluoxetine0low10
glyburide0low30
metformin0low10
apnea0low10
nifedipine0low90
phenobarbital0low10
4-phenylbutyric acid0low10
potassium chloride0low20
propofol0low10
tolbutamide0low30
thyroxine0medium11
alanine0low10
glutamine0low10
adenosine diphosphate0low20
galactose0low10
levodopa0low80
tyrosine0low10
leucine0low30
phenylalanine0low10
isoleucine0low10
arginine0low10
megestrol acetate0low10
phenyl acetate0low20
glutamic acid0low20
adenylyl imidodiphosphate0low10
s-adenosylmethionine0low10
nicorandil0low10
fluorodopa f 180medium271
fluorodeoxyglucose f180low30
phorbol-12-myristate0low10
5-fluorodopa0low20
glycerophosphoinositol 4,5-bisphosphate0low10
proline0low10
edotreotide0low10
glycogen0medium21
bilirubin0low10
sirolimus0low240
everolimus0low10
atrial natriuretic factor0low10
glucagon-like peptide 10medium71
incretins0low30
c-peptide0low110
exendin (9-39)0medium52
exenatide0low30
natriuretic peptide, brain0low10
kiss1 protein, human0low10
humulin s0low10
68ga-dotanoc0low20
guanosine triphosphate0low20
sildenafil citrate0low10
maltodextrin0low10
carbidopa0low10

Protein Targets (1,023)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Protein skinhead-10101
Monocarboxylate transporter 20101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE100010
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE0011
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE0011
mitogen-activated protein kinase 14004
survival motor neuron protein isoform d4004
Histone deacetylase 30404
Histone deacetylase 40404
Histone deacetylase 10404
Histone deacetylase 70404
Histone deacetylase 20404
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Histone deacetylase 80404
NAD-dependent protein deacylase sirtuin-5, mitochondrial0202
Histone deacetylase 60404
Histone deacetylase 90404
Histone deacetylase 50404
Chain A, Heat Shock Protein 900011
Chain A, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain B, GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE0011
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, EOSINOPHIL-DERIVED NEUROTOXIN0101
Chain A, Myosin Ie Heavy Chain0011
Chain A, Preprotein translocase secA0011
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Ribonuclease pancreatic0101
Chain A, Phosphoribosylformylglycinamidine synthase0101
Chain A, nucleoside diphosphate kinase A0011
Chain B, nucleoside diphosphate kinase A0011
Chain D, DNA polymerase III subunit gamma0011
Chain D, DNA polymerase III subunit gamma0011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 30011
Chain A, Kinesin-like protein KIF110101
regulator of G-protein signaling 47007
HPr kinase/phosphorylase0011
Mitogen-activated protein kinase kinase kinase 70011
ATP-dependent molecular chaperone HSP820001
Heat shock protein HSP 90-alpha0113
Heat shock protein HSP 90-beta0113
2-dehydropantoate 2-reductase0123
Heat shock 70 kDa protein 1A 0112
Endoplasmic reticulum chaperone BiP0011
Heat shock cognate 71 kDa protein0011
Pyruvate kinase PKM 0001
Pyruvate kinase PKLR 0001
Endoplasmin0001
Heat shock cognate 71 kDa protein0011
5'-nucleotidase0202
Mu-type opioid receptor0224
Delta-type opioid receptor0213
Kappa-type opioid receptor0213
Endoplasmin0112
P2Y purinoceptor 20011
Phosphatidylinositol 4-kinase alpha0202
P2X purinoceptor 10011
P2Y purinoceptor 10011
P2Y purinoceptor 10011
P2X purinoceptor 10011
P2X purinoceptor 40011
P2X purinoceptor 50011
P2X purinoceptor 60011
P2X purinoceptor 30011
Inositol monophosphatase 14004
Heat shock protein 75 kDa, mitochondrial0101
P2Y purinoceptor 60011
Phosphatidylinositol 4-kinase type 2-beta0202
P2Y purinoceptor 110011
Phosphatidylinositol 4-kinase type 2-alpha0202
P2Y purinoceptor 120011
Sensor protein kinase WalK0202
Phosphatidylinositol 4-kinase beta0202
P2X purinoceptor 20011
Chain A, Carbamoyl-phosphate Synthase0101
Chain A, Potassium-transporting ATPase B chain0011
S-adenosylmethionine synthase isoform type-10101
S-adenosylmethionine synthase isoform type-20101
Glycine--tRNA ligase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE7007
Carbonic anhydrase 10209
Carbonic anhydrase 20209
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0001
Glutamate receptor ionotropic, NMDA 1 06211
Proton-coupled amino acid transporter 10607
Adenosine deaminase0001
Carbonic anhydrase 40001
thioredoxin reductase9009
ATAD5 protein, partial3003
TDP1 protein140014
Microtubule-associated protein tau5005
estrogen-related nuclear receptor alpha110011
arylsulfatase A4004
euchromatic histone-lysine N-methyltransferase 2160016
Bloom syndrome protein isoform 18008
D(1A) dopamine receptor5005
lamin isoform A-delta10140014
neuropeptide S receptor isoform A2002
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase6006
NFKB1 protein, partial3003
GLS protein9009
thyroid stimulating hormone receptor8008
alpha-galactosidase1001
cytochrome P450 2C19 precursor4004
chromobox protein homolog 17007
flap endonuclease 13003
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M17007
lethal factor (plasmid)4004
Cytochrome P450 3A40304
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
ATP-dependent phosphofructokinase6006
Atrial natriuretic peptide receptor 10112
Atrial natriuretic peptide receptor 1 0011
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, 2-oxoglutarate Oxygenase4004
Chain A, Cruzipain2002
USP1 protein, partial100010
aldehyde dehydrogenase 1 family, member A16006
vitamin D3 receptor isoform VDRA3003
DNA polymerase kappa isoform 16006
caspase-1 isoform alpha precursor1001
Caspase-72002
Solute carrier organic anion transporter family member 1B30203
Solute carrier organic anion transporter family member 1B10406
Chain A, Beta-lactamase5005
acetylcholinesterase4004
RAR-related orphan receptor gamma7007
AR protein130013
glucocorticoid receptor [Homo sapiens]100010
retinoic acid nuclear receptor alpha variant 19009
pregnane X nuclear receptor110011
estrogen nuclear receptor alpha170017
IDH13003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
thyroid hormone receptor beta isoform a5005
nuclear factor erythroid 2-related factor 2 isoform 22002
geminin130013
Vpr1001
ATP-binding cassette sub-family C member 3012012
Multidrug resistance-associated protein 4012012
Bile salt export pump0606
Bile salt export pump017017
Albumin0033
Major prion protein0011
Cellular tumor antigen p538008
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2C9 0808
UDP-glucuronosyltransferase 2B70204
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0203
Cytochrome P450 2J20303
Potassium voltage-gated channel subfamily H member 20808
Sodium channel protein type 9 subunit alpha0303
Frizzled-80011
Canalicular multispecific organic anion transporter 1011011
P2X purinoceptor 40101
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
EWS/FLI fusion protein5005
nonstructural protein 13003
transcriptional regulator ERG isoform 31001
nuclear factor erythroid 2-related factor 2 isoform 18008
cytochrome P450 3A4 isoform 15005
Gamma-aminobutyric acid receptor subunit pi5117
Gamma-aminobutyric acid receptor subunit beta-15117
Gamma-aminobutyric acid receptor subunit delta5117
Gamma-aminobutyric acid receptor subunit gamma-25117
Gamma-aminobutyric acid receptor subunit alpha-55117
Gamma-aminobutyric acid receptor subunit alpha-35117
Gamma-aminobutyric acid receptor subunit gamma-15117
Gamma-aminobutyric acid receptor subunit alpha-25117
Gamma-aminobutyric acid receptor subunit alpha-45117
Gamma-aminobutyric acid receptor subunit gamma-35117
Gamma-aminobutyric acid receptor subunit alpha-65117
Gamma-aminobutyric acid receptor subunit alpha-15117
Gamma-aminobutyric acid receptor subunit beta-35117
Gamma-aminobutyric acid receptor subunit beta-25117
GABA theta subunit5117
Gamma-aminobutyric acid receptor subunit epsilon5117
ORF730011
Sodium- and chloride-dependent creatine transporter 10101
Chain A, Ferritin light chain3003
cytochrome P450 2D6 isoform 13003
importin subunit beta-1 isoform 13003
snurportin-13003
GTP-binding nuclear protein Ran isoform 11001
nuclear receptor ROR-gamma isoform 15005
peripheral myelin protein 228008
histone acetyltransferase KAT2A isoform 14004
Coagulation factor VII0101
Tissue factor0202
Glutamate receptor 11216
Glutamate receptor 23218
Glutamate receptor 31216
Glutamate receptor 41216
Nicotinamide phosphoribosyltransferase0011
ATP-binding cassette sub-family C member 80213
ATP-sensitive inward rectifier potassium channel 110213
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
endonuclease IV1001
15-lipoxygenase, partial4004
cytochrome P450 family 3 subfamily A polypeptide 49009
polyunsaturated fatty acid lipoxygenase ALOX122002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Epidermal growth factor receptor0224
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
peroxisome proliferator activated receptor gamma8008
thyroid hormone receptor beta isoform 26006
Bone morphogenetic protein receptor type-1B0022
Cell division cycle 7-related protein kinase0022
Serine/threonine-protein kinase PLK40022
ATP-dependent RNA helicase DDX3X0022
Pyridoxal kinase0022
Citron Rho-interacting kinase0022
Serine/threonine-protein kinase Chk10022
Aurora kinase A0022
Cyclin-G-associated kinase0022
Ephrin type-B receptor 60022
Peroxisomal acyl-coenzyme A oxidase 30022
Receptor-interacting serine/threonine-protein kinase 20022
Mitotic checkpoint serine/threonine-protein kinase BUB10022
Dynamin-like 120 kDa protein, mitochondrial0022
Eukaryotic translation initiation factor 5B0022
Rho-associated protein kinase 20022
Serine/threonine-protein kinase ULK10022
Serine/threonine-protein kinase/endoribonuclease IRE10022
Ribosomal protein S6 kinase alpha-50022
U5 small nuclear ribonucleoprotein 200 kDa helicase0022
Ribosomal protein S6 kinase alpha-40022
Serine/threonine-protein kinase 160022
Serine/threonine-protein kinase 100022
Serine/threonine-protein kinase D30022
Structural maintenance of chromosomes protein 20022
Mitogen-activated protein kinase kinase kinase 60022
Mitogen-activated protein kinase kinase kinase kinase 40022
Serine/threonine-protein kinase LATS10022
Serine/threonine-protein kinase PAK 40022
Tyrosine-protein kinase ABL10022
High affinity nerve growth factor receptor0022
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20022
Protein kinase C beta type0022
Insulin receptor0022
Tyrosine-protein kinase Lck0123
Tyrosine-protein kinase Fyn0123
Cyclin-dependent kinase 10022
Glycogen phosphorylase, liver form0022
Tyrosine-protein kinase Fes/Fps0022
Adenine phosphoribosyltransferase0022
Tyrosine-protein kinase Yes0022
Tyrosine-protein kinase Lyn0022
Proto-oncogene tyrosine-protein kinase receptor Ret0022
Insulin-like growth factor 1 receptor0022
Signal recognition particle receptor subunit alpha0022
Cytochrome c1, heme protein, mitochondrial0022
Hepatocyte growth factor receptor0022
Tyrosine-protein kinase HCK0022
Platelet-derived growth factor receptor beta0022
Tyrosine-protein kinase Fgr0022
Serine/threonine-protein kinase A-Raf0022
Glycogen phosphorylase, brain form0022
Breakpoint cluster region protein0022
Serine/threonine-protein kinase pim-10022
Fibroblast growth factor receptor 10022
DNA topoisomerase 2-alpha0022
Cyclin-dependent kinase 40022
ADP/ATP translocase 30022
Inosine-5'-monophosphate dehydrogenase 20022
Proto-oncogene tyrosine-protein kinase Src0022
cAMP-dependent protein kinase type II-alpha regulatory subunit0022
Serine/threonine-protein kinase B-raf0022
Potassium voltage-gated channel subfamily E member 10101
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0022
Ribosyldihydronicotinamide dehydrogenase [quinone]0022
Tyrosine-protein kinase Fer0022
Protein kinase C alpha type0022
cAMP-dependent protein kinase catalytic subunit alpha0022
General transcription and DNA repair factor IIH helicase subunit XPD0022
Casein kinase II subunit alpha'0022
Ras-related protein Rab-6A0022
Ephrin type-A receptor 10022
Multifunctional protein ADE20022
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0022
Ferrochelatase, mitochondrial0022
Ribosomal protein S6 kinase beta-10022
Tyrosine-protein kinase JAK10022
Cyclin-dependent kinase 20022
Beta-adrenergic receptor kinase 10022
Probable ATP-dependent RNA helicase DDX60022
Mitogen-activated protein kinase 3 0022
MAP/microtubule affinity-regulating kinase 30022
Deoxycytidine kinase0022
Mitogen-activated protein kinase 10022
Ephrin type-A receptor 20022
Ephrin type-B receptor 20022
Non-receptor tyrosine-protein kinase TYK20022
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10022
Wee1-like protein kinase0022
Heme oxygenase 20022
S-adenosylmethionine synthase isoform type-20022
DnaJ homolog subfamily A member 10022
RAC-alpha serine/threonine-protein kinase0022
RAC-beta serine/threonine-protein kinase0022
Dual specificity protein kinase TTK0022
DNA replication licensing factor MCM40022
Myosin-100022
Dual specificity mitogen-activated protein kinase kinase 20022
Receptor-type tyrosine-protein kinase FLT30022
Bone morphogenetic protein receptor type-1A0022
Activin receptor type-1B0022
TGF-beta receptor type-10022
TGF-beta receptor type-20022
Electron transfer flavoprotein subunit beta0022
Tyrosine-protein kinase CSK0022
Glycine--tRNA ligase0022
Protein kinase C iota type0022
Exosome RNA helicase MTR40022
Serine/threonine-protein kinase mTOR0224
Tyrosine-protein kinase Tec0022
Tyrosine-protein kinase ABL20022
Tyrosine-protein kinase FRK0022
G protein-coupled receptor kinase 60022
Tyrosine-protein kinase SYK0022
26S proteasome regulatory subunit 6B0022
Mitogen-activated protein kinase 80022
Mitogen-activated protein kinase 90022
Dual specificity mitogen-activated protein kinase kinase 30022
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0022
Casein kinase I isoform alpha0022
Casein kinase I isoform delta0022
MAP kinase-activated protein kinase 20022
Elongation factor Tu, mitochondrial0022
Choline-phosphate cytidylyltransferase A0022
Cysteine--tRNA ligase, cytoplasmic0022
Casein kinase I isoform epsilon0022
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0022
Dual specificity protein kinase CLK10022
Dual specificity protein kinase CLK20022
Dual specificity protein kinase CLK30022
Glycogen synthase kinase-3 alpha0022
Glycogen synthase kinase-3 beta0022
Cyclin-dependent kinase 70022
Cyclin-dependent kinase 90022
Ras-related protein Rab-27A0022
Interleukin-1 receptor-associated kinase 10022
Potassium voltage-gated channel subfamily KQT member 10101
Ribosomal protein S6 kinase alpha-30022
Serine/threonine-protein kinase Nek20022
Serine/threonine-protein kinase Nek30022
Dual specificity mitogen-activated protein kinase kinase 60022
Serine/threonine-protein kinase PLK10022
LIM domain kinase 10022
LIM domain kinase 20022
Mitogen-activated protein kinase 100022
Tyrosine--tRNA ligase, cytoplasmic0022
5'-AMP-activated protein kinase subunit gamma-10022
Ephrin type-B receptor 30022
Ephrin type-A receptor 50022
Ephrin type-B receptor 40022
Ephrin type-A receptor 40022
Adenylate kinase 2, mitochondrial0022
Adenosine kinase0022
Ras-related protein Rab-100022
Actin-related protein 30022
Actin-related protein 20022
GTP-binding nuclear protein Ran0022
Casein kinase I isoform gamma-20022
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60022
Cyclin-dependent-like kinase 5 0022
Cyclin-dependent kinase 160022
Cyclin-dependent kinase 170022
ATP-dependent 6-phosphofructokinase, platelet type0022
Dual specificity mitogen-activated protein kinase kinase 10022
DNA topoisomerase 2-beta0022
Protein kinase C theta type0022
Activin receptor type-10022
Macrophage-stimulating protein receptor0022
Focal adhesion kinase 10022
Protein kinase C delta type0022
Tyrosine-protein kinase BTK0022
Activated CDC42 kinase 10022
Epithelial discoidin domain-containing receptor 10022
Mitogen-activated protein kinase kinase kinase kinase 20022
Serine/threonine-protein kinase 40022
5'-AMP-activated protein kinase catalytic subunit alpha-10022
Dual specificity mitogen-activated protein kinase kinase 50022
Mitogen-activated protein kinase 70022
Serine/threonine-protein kinase PAK 20022
Serine/threonine-protein kinase 30022
Mitogen-activated protein kinase kinase kinase 10022
Integrin-linked protein kinase0022
Rho-associated protein kinase 10022
Non-receptor tyrosine-protein kinase TNK10022
Calcium/calmodulin-dependent protein kinase type II subunit gamma0022
Calcium/calmodulin-dependent protein kinase type II subunit delta0022
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0022
Activin receptor type-2B0022
Bone morphogenetic protein receptor type-20022
Protein-tyrosine kinase 60022
cGMP-dependent protein kinase 1 0022
Cyclin-dependent kinase 130022
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0022
Protein-tyrosine kinase 2-beta0022
Sodium channel protein type 5 subunit alpha0202
Maternal embryonic leucine zipper kinase0022
Structural maintenance of chromosomes protein 1A0022
Chromodomain-helicase-DNA-binding protein 40022
Peroxisomal acyl-coenzyme A oxidase 10022
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0022
Ribosomal protein S6 kinase alpha-10022
Dual specificity testis-specific protein kinase 10022
Myosin light chain kinase, smooth muscle0123
Mitogen-activated protein kinase 110022
Serine/threonine-protein kinase STK110022
Serine/threonine-protein kinase N10022
Serine/threonine-protein kinase N20022
Mitogen-activated protein kinase 140022
Calcium/calmodulin-dependent protein kinase type IV0022
Mitogen-activated protein kinase kinase kinase 110022
Discoidin domain-containing receptor 20022
AP2-associated protein kinase 10022
Myosin light chain kinase 30022
Putative heat shock protein HSP 90-beta 20022
Serine/threonine-protein kinase MRCK alpha0022
Serine/threonine-protein kinase MRCK gamma0022
Acyl-CoA dehydrogenase family member 100022
Serine/threonine-protein kinase N30022
Serine/threonine-protein kinase ULK30022
Uncharacterized protein FLJ452520022
Acyl-CoA dehydrogenase family member 110022
Serine/threonine-protein kinase/endoribonuclease IRE20022
Serine/threonine-protein kinase MARK20022
ATP-dependent RNA helicase DHX300022
Serine/threonine-protein kinase TAO10022
STE20-related kinase adapter protein alpha0022
Myosin-140022
AarF domain-containing protein kinase 10022
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30022
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Regulatory-associated protein of mTOR0202
Atypical kinase COQ8A, mitochondrial0022
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0022
Mitogen-activated protein kinase 150022
Serine/threonine-protein kinase Nek90022
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10022
Mitogen-activated protein kinase kinase kinase kinase 10022
Aurora kinase B0022
MAP/microtubule affinity-regulating kinase 40022
Serine/threonine-protein kinase Nek10022
ATPase family AAA domain-containing protein 54004
PAS domain-containing serine/threonine-protein kinase0022
Calcium/calmodulin-dependent protein kinase kinase 20022
EKC/KEOPS complex subunit TP53RK0022
Dual specificity testis-specific protein kinase 20022
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0022
Mitogen-activated protein kinase kinase kinase 50022
Ataxin-25005
Mitogen-activated protein kinase kinase kinase 30022
Eukaryotic translation initiation factor 2-alpha kinase 10022
Target of rapamycin complex subunit LST80202
Nucleolar GTP-binding protein 10022
Serine/threonine-protein kinase D20022
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0022
Serine/threonine-protein kinase SIK20022
STE20-like serine/threonine-protein kinase 0022
Serine/threonine-protein kinase TAO30022
dCTP pyrophosphatase 10022
Dual specificity protein kinase CLK40022
Casein kinase I isoform gamma-10022
Phenylalanine--tRNA ligase beta subunit0022
BMP-2-inducible protein kinase0022
Obg-like ATPase 10022
Midasin0022
Interleukin-1 receptor-associated kinase 40022
Mitogen-activated protein kinase kinase kinase 200022
Cyclin-dependent kinase 120022
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260022
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0022
Serine/threonine-protein kinase NLK0022
5'-AMP-activated protein kinase subunit gamma-20022
Serine/threonine-protein kinase TBK10022
Septin-90022
Potassium voltage-gated channel subfamily D member 30101
Ribosomal protein S6 kinase alpha-60022
TRAF2 and NCK-interacting protein kinase0022
Serine/threonine-protein kinase TAO20022
Long-chain-fatty-acid--CoA ligase 50011
RAC-gamma serine/threonine-protein kinase0022
Serine/threonine-protein kinase SIK30022
Mitogen-activated protein kinase kinase kinase 20022
Thyroid hormone receptor-associated protein 30022
Mitogen-activated protein kinase kinase kinase kinase 50022
Receptor-interacting serine/threonine-protein kinase 30022
Serine/threonine-protein kinase MRCK beta0022
Interleukin-1 receptor-associated kinase 30022
Casein kinase I isoform gamma-30022
Mitogen-activated protein kinase kinase kinase 40022
Luciferase6006
potassium voltage-gated channel subfamily H member 2 isoform d5005
Solute carrier family 22 member 1 0202
Nuclear receptor subfamily 1 group I member 20033
ATP-dependent translocase ABCB10404
D(2) dopamine receptor0101
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0213
Kappa-type opioid receptor0101
Histamine H1 receptor0101
D(3) dopamine receptor0101
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10202
GLI family zinc finger 39009
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)1001
nuclear receptor subfamily 1, group I, member 37007
progesterone receptor6006
retinoid X nuclear receptor alpha5005
G8008
cytochrome P450 2D63003
peroxisome proliferator-activated receptor delta5005
caspase-32002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)5005
Histone H2A.x2002
Caspase-71001
NPC intracellular cholesterol transporter 1 precursor1001
caspase-31001
huntingtin isoform 21001
atrial natriuretic peptide receptor 2 precursor2002
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 12002
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Sodium-dependent noradrenaline transporter0101
5-hydroxytryptamine receptor 40606
Voltage-dependent calcium channel gamma-2 subunit2002
Potassium channel subfamily K member 20134
Interferon beta8008
HLA class I histocompatibility antigen, B alpha chain 8008
Aldo-keto reductase family 1 member B10505
5-hydroxytryptamine receptor 2C0202
Muscarinic acetylcholine receptor M50203
Alpha-2A adrenergic receptor0101
Cytochrome P450 2C80101
Cytochrome P450 2D60101
Muscarinic acetylcholine receptor M10203
Angiotensin-converting enzyme0202
Dipeptidyl peptidase 40101
5-hydroxytryptamine receptor 2A0404
Gamma-aminobutyric acid receptor subunit alpha-10213
Alpha-1B adrenergic receptor0404
Alpha-2B adrenergic receptor0202
Gamma-aminobutyric acid receptor subunit beta-10112
Gamma-aminobutyric acid receptor subunit gamma-20213
Alpha-2B adrenergic receptor0101
Muscarinic acetylcholine receptor M30203
Acetylcholinesterase0101
Alpha-2C adrenergic receptor0101
Acetylcholinesterase0101
Alpha-2A adrenergic receptor0101
Prostaglandin G/H synthase 10202
Alpha-1D adrenergic receptor0202
Sodium-dependent noradrenaline transporter 0415
Sodium-dependent dopamine transporter0202
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0606
Gamma-aminobutyric acid receptor subunit beta-30213
5-hydroxytryptamine receptor 2B0202
Gamma-aminobutyric acid receptor subunit alpha-50112
Sodium-dependent serotonin transporter0224
Sodium-dependent serotonin transporter0202
Cytochrome P450 2C190202
Gamma-aminobutyric acid receptor subunit alpha-30112
Alpha-1A adrenergic receptor0404
Gamma-aminobutyric acid receptor subunit alpha-20112
Gamma-aminobutyric acid receptor subunit beta-20112
Gamma-aminobutyric acid receptor subunit alpha-40112
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Spike glycoprotein3003
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gastrin/cholecystokinin type B receptor 0101
Sodium-dependent dopamine transporter 0213
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Gamma-aminobutyric acid receptor subunit alpha-60112
Cytochrome P450 1B10101
Sigma intracellular receptor 20101
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0101
Nuclear receptor subfamily 3 group C member 3 0202
Beta-2 adrenergic receptor0102
Gamma-aminobutyric acid receptor subunit gamma-10101
Inositol hexakisphosphate kinase 18008
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0101
Histamine H3 receptor0101
cytochrome P450 2C9, partial8008
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Glucagon-like peptide 1 receptor0011
Glucagon-like peptide 1 receptor0112
Glucagon receptor0011
Glucagon receptor0011
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
glp-1 receptor, partial1001
beta-2 adrenergic receptor3003
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0404
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Integrin beta-31012
Integrin alpha-IIb1012
ATP-citrate synthase 0101
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, NMDA 2A 0429
Glutamate receptor ionotropic, NMDA 2B0429
Glutamate receptor ionotropic, NMDA 2C0429
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0005
Glutamate receptor ionotropic, NMDA 2D0429
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0429
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0429
Chain A, Glutamine Binding Protein0011
peripheral myelin protein 22 isoform 13003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
Neutral amino acid transporter A0202
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0202
Amino acid transporter0202
SMAD family member 24004
SMAD family member 34004
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)5005
Parkin2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
cytochrome P450 2C9 precursor3003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Solute carrier family 22 member 60202
ATP-binding cassette sub-family C member 90101
Solute carrier organic anion transporter family member 2B1 0001
Chymotrypsinogen A0101
Beta-lactamase0101
ATP synthase subunit beta, mitochondrial0101
ATP synthase subunit delta, mitochondrial0101
ATP synthase subunit gamma, mitochondrial0101
ATP synthase subunit epsilon, mitochondrial0101
Cystic fibrosis transmembrane conductance regulator0101
5-hydroxytryptamine receptor 1A0101
Cholesteryl ester transfer protein0101
Peroxisome proliferator-activated receptor gamma0123
Malate dehydrogenase, cytoplasmic0101
Histamine H2 receptor3003
Solute carrier family 15 member 10101
Guanine nucleotide-binding protein G1001
Solute carrier family 22 member 70101
Solute carrier family 15 member 20101
NACHT, LRR and PYD domains-containing protein 3 0101
NACHT, LRR and PYD domains-containing protein 3 0101
CDGSH iron-sulfur domain-containing protein 10202
Broad substrate specificity ATP-binding cassette transporter ABCG20303
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10607
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
67.9K protein3003
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
Chain A, AMINOPEPTIDASE0202
Chain A, AMINOPEPTIDASE0202
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
Intestinal-type alkaline phosphatase0202
Phospholipase A-2-activating protein0202
Chain A, JmjC domain-containing histone demethylation protein 3A2002
dopamine D1 receptor1001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
apical membrane antigen 1, AMA12002
vitamin D (1,25- dihydroxyvitamin D3) receptor3003
pyruvate kinase1001
hexokinase-4 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
glucokinase regulatory protein1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
DNA polymerase eta isoform 12002
M-phase phosphoprotein 82002
Polyphenol oxidase 20002
Carbonic anhydrase 120004
Plasma kallikrein0003
Carbonic anhydrase 30004
Polyunsaturated fatty acid lipoxygenase ALOX150303
Tyrosinase0101
Carbonic anhydrase 40105
Carbonic anhydrase 60004
Adenosine receptor A10003
Adenosine receptor A2a0104
Carbonic anhydrase 5A, mitochondrial0105
Carbonic anhydrase0003
Carbonic anhydrase 70004
Solute carrier family 15 member 10101
Carbonic anhydrase0003
SLC16A10 protein0003
Carbonic anhydrase 90105
Carbonic anhydrase 0003
Carbonic anhydrase0003
Carbonic anhydrase0003
Carbonic anhydrase 0003
Monocarboxylate transporter 100003
Carbonic anhydrase 150003
Carbonic anhydrase 130003
Carbonic anhydrase 140004
Carbonic anhydrase 5B, mitochondrial0004
phosphoglycerate kinase1001
farnesoid X nuclear receptor4004
bioA0001
nuclear receptor subfamily 1, group I, member 22002
DNA polymerase beta1001
muscleblind-like protein 1 isoform 13003
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Androgen receptor0202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Solute carrier family 22 member 20101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Solute carrier family 22 member 10001
Multidrug and toxin extrusion protein 10101
pregnane X receptor2002
hypoxia-inducible factor 1 alpha subunit1001
Fumarate hydratase1001
Thrombopoietin1001
Smad32002
hypothetical protein, conserved1001
polyprotein1001
bromodomain adjacent to zinc finger domain 2B1001
aryl hydrocarbon receptor2002
thyroid stimulating hormone receptor1001
cellular tumor antigen p53 isoform a1001
tumor necrosis factor1001
perilipin-50101
perilipin-10101
heat shock protein beta-12002
serine/threonine-protein kinase PLK12002
eyes absent homolog 2 isoform a1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Cytochrome P450 1A20101
Muscarinic acetylcholine receptor M20001
Muscarinic acetylcholine receptor M40001
Adenosine receptor A30202
Phospholipase A2, membrane associated0001
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Thromboxane-A synthase 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A2a0101
Adenosine receptor A10202
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Sodium channel protein type 1 subunit alpha0202
C-C chemokine receptor type 20202
Nuclear receptor ROR-gamma2002
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
C-terminal-binding protein 11001
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0203
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Leukotriene B4 receptor 10001
Transient receptor potential cation channel subfamily A member 10011
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Sodium channel protein type 2 subunit alpha0202
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Leukotriene B4 receptor 20001
Sodium channel protein type 3 subunit alpha0202
Sodium channel protein type 11 subunit alpha0101
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
E3 ubiquitin-protein ligase XIAP0101
Large neutral amino acids transporter small subunit 1 0101
Carbonic anhydrase 130001
Taste receptor type 2 member 310011
Taste receptor type 2 member 600011
Sodium/potassium/calcium exchanger 40112
Taste receptor type 2 member 140012
Taste receptor type 2 member 130011
Taste receptor type 2 member 90011
Taste receptor type 2 member 40011
Sodium/potassium/calcium exchanger 20112
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
activating transcription factor 61001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90002
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
5-hydroxytryptamine receptor 2B0202
Sodium- and chloride-dependent betaine transporter0101
UDP-glucuronosyltransferase 1A80001
Met repressor 0022
Protein arginine N-methyltransferase 50011
Histone H3K27 methylase0001
Phenylethanolamine N-methyltransferase0012
S-adenosylmethionine decarboxylase proenzyme0102
Protein-L-isoaspartate(D-aspartate) O-methyltransferase0101
Catechol O-methyltransferase0001
Protein arginine N-methyltransferase 10101
Methylosome protein 500011
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Tyrosine-protein kinase JAK20011
Cyclin-dependent kinase-like 50011
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Eukaryotic translation initiation factor 4E0011
Peptidyl-prolyl cis-trans isomerase FKBP1A0101
Serine/threonine-protein kinase receptor R30011
Alpha-synuclein1001
Peptidyl-prolyl cis-trans isomerase FKBP1A0213
Peptidyl-prolyl cis-trans isomerase FKBP1B0011
Protein kinase C zeta type0011
Cyclin-dependent kinase 180011
Tyrosine-protein kinase Mer0011
Peptidyl-prolyl cis-trans isomerase FKBP50101
Uncharacterized aarF domain-containing protein kinase 50011
Programmed cell death protein 40011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase mTOR 0101
Isoleucine--tRNA ligase, mitochondrial0011
Serine/threonine-protein kinase ICK0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Serine/threonine-protein kinase 240011
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Rap guanine nucleotide exchange factor 31001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0202
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Albumin0112
UDP-glucuronosyltransferase 1-60102
UDP-glucuronosyltransferase 1A40101
UDP-glucuronosyltransferase 2B10 0101
Lanosterol 14-alpha demethylase0101
Chain A, CHORISMATE MUTASE0101
Chain A, TYROSYL-tRNA SYNTHETASE0011
Tubulin--tyrosine ligase0101
Cocaine esterase0101
Cytochrome P450 2A60101
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]