Page last updated: 2024-09-28

Congenital Foot Deformities

Alterations or deviations from normal shape or size which result in a disfigurement of the foot occurring at or before birth.

Synonyms(6)

Synonym
Deformity, Congenital Foot
Foot Deformity, Congenital
Foot Deformities, Congenital
Congenital Foot Deformity
Congenital Foot Deformities
Deformities, Congenital Foot

Research

Studies (367)

TimeframeStudies, This Condition (%)All Conditions %
pre-1990211 (57.49)23.3326
1990's54 (14.71)12.5806
2000's49 (13.35)18.1394
2010's42 (11.44)28.8240
2020's11 (3.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbamates0low10
salicylic acid0low150
cytosine0low10
iodine0low10
thymine0low10
uric acid0low10
3-methylcholanthrene0low10
phenytoin0low20
acetazolamide0low10
baclofen0low10
bisoprolol0low10
bupivacaine0low30
busulfan0low10
valproic acid0low50
fluorouracil0low20
lidocaine0low10
1-methyl-3-isobutylxanthine0low10
2-propanol0low50
khellin0low10
mechlorethamine0low10
midazolam0low10
ofloxacin0low10
phenobarbital0low10
prilocaine0low10
proadifen0low10
procarbazine0low10
sevoflurane0low10
sumatriptan0low10
thalidomide0low30
lysergic acid diethylamide0low20
thyroxine0low10
penicillamine0low10
alanine0low10
serine0low40
lysine0low30
bromodeoxyuridine0low10
methylene blue0low10
dimethylnitrosamine0low10
histidine0low10
tryptophan0low20
arginine0low40
isoprene0low10
2,3,5-triiodobenzoic acid0low10
piperazine adipate0low10
aminophylline0low10
hydantoins0low20
methoxyacetic acid0low10
methylnitrosourea0low10
cadmium0low20
zinc sulfate0low10
aluminum sulfate0low10
cadmium sulfate0low10
trolamine salicylate0low80
phenyl acetate0low10
cetylpyridinium chloride anhydrous0low10
glutamic acid0low10
methyl(acetoxymethyl)nitrosamine0low10
propiconazole0low30
fomesafen0low20
imiquimod0low10
levobupivacaine0low10
methotrexate0low30
proline0low20
naproxen0low10
elastin0low20
oxytocin0low10
inositol 3-phosphate0low70
iduronate0low10
tretinoin0low30
cocaine0low10
bromochloroacetic acid0low10
thioinosine0low10
dieldrin0low10
enclomiphene0low10
ethylenethiourea0low10
dermatan sulfate0low10
humulene0low10
misoprostol0low20
phenylephrine hydrochloride0low330
geldanamycin0low10
cysteine0low20
phosphorus0low20
technetium tc 99m diphosphonate0low10
sodium ethylxanthate0low10
endrin0low10
chondroitin0low10
salicylates0low10
transforming growth factor beta0low10
aldrin0low10
technetium tc 99m medronate0low20
chondroitin sulfates0low20
folic acid0low10
eye0low10

Protein Targets (940)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Chain A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Chain A, Phosphodiesterase 9A0101
Chain A, JmjC domain-containing histone demethylation protein 3A4004
Chain A, Class I phosphodiesterase PDEB10101
Chain A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
Chain A, cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, cGMP-specific 3',5'-cyclic phosphodiesterase catalytic domain, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha chimera0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Chain A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
glp-1 receptor, partial9009
thyroid stimulating hormone receptor110011
estrogen-related nuclear receptor alpha330033
Phosphodiesterase 0101
mitogen-activated protein kinase 16006
geminin210021
cytochrome P450 3A4 isoform 18008
histone acetyltransferase KAT2A isoform 19009
cGMP-dependent 3',5'-cyclic phosphodiesterase0101
Gamma-aminobutyric acid receptor subunit pi84012
Monocarboxylate transporter 40101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0202
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A0101
Renin0303
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Gamma-aminobutyric acid receptor subunit beta-184012
Gamma-aminobutyric acid receptor subunit delta84012
Gamma-aminobutyric acid receptor subunit gamma-284113
Gamma-aminobutyric acid receptor subunit alpha-584012
Gamma-aminobutyric acid receptor subunit alpha-384012
Gamma-aminobutyric acid receptor subunit gamma-185013
Gamma-aminobutyric acid receptor subunit alpha-284012
Adenosine receptor A10405
Gamma-aminobutyric acid receptor subunit alpha-484012
Gamma-aminobutyric acid receptor subunit gamma-384012
Adenosine receptor A30101
Adenosine receptor A2a0203
Adenosine receptor A2b0001
Adenosine receptor A2b0202
Gamma-aminobutyric acid receptor subunit alpha-684012
Adenosine receptor A10013
Adenosine receptor A2a0405
Sodium-dependent serotonin transporter0506
Adenosine receptor A2a0101
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Gamma-aminobutyric acid receptor subunit alpha-184113
Gamma-aminobutyric acid receptor subunit beta-384012
Gamma-aminobutyric acid receptor subunit beta-284113
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
Voltage-dependent L-type calcium channel subunit alpha-1C0213
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Phosphodiesterase 0101
GABA theta subunit84012
Phosphodiesterase 0101
Gamma-aminobutyric acid receptor subunit epsilon84012
cAMP-specific 3',5'-cyclic phosphodiesterase 7B0101
hypoxia-inducible factor 1 alpha subunit100010
RAR-related orphan receptor gamma230023
GLI family zinc finger 3230023
AR protein310031
aldehyde dehydrogenase 1 family, member A1200020
retinoic acid nuclear receptor alpha variant 1260026
retinoid X nuclear receptor alpha190019
estrogen nuclear receptor alpha350035
peroxisome proliferator-activated receptor delta120012
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a180018
activating transcription factor 6100010
v-jun sarcoma virus 17 oncogene homolog (avian)110011
Histone H2A.x9009
thyroid hormone receptor beta isoform a110011
heat shock protein beta-18008
nuclear factor erythroid 2-related factor 2 isoform 1250025
lamin isoform A-delta10200020
Voltage-dependent calcium channel gamma-2 subunit130013
Glutamate receptor 2132116
peroxisome proliferator activated receptor gamma180018
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
thyroid hormone receptor beta isoform 2160016
Luciferase9009
pregnane X receptor7007
phosphopantetheinyl transferase140014
SMAD family member 26006
SMAD family member 36006
TDP1 protein280028
Microtubule-associated protein tau160016
caspase 7, apoptosis-related cysteine protease4004
nuclear receptor subfamily 1, group I, member 3210021
farnesoid X nuclear receptor120012
pregnane X nuclear receptor210021
caspase-34004
euchromatic histone-lysine N-methyltransferase 2240024
aryl hydrocarbon receptor150015
Cellular tumor antigen p53200020
Cytochrome P450 1A20516
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0202
Aldo-keto reductase family 1 member B10505
Adenosine receptor A30606
Alpha-1B adrenergic receptor0808
Acetylcholinesterase0202
Sodium-dependent noradrenaline transporter 0617
Aryl hydrocarbon receptor0011
Alpha-1A adrenergic receptor0808
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase7007
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
thioredoxin reductase170017
GALC protein3003
cytochrome P450 family 3 subfamily A polypeptide 4120012
glucocorticoid receptor [Homo sapiens]180018
Carbonic anhydrase 0101
Carbonic anhydrase 0101
arylsulfatase A110011
Carbonic anhydrase0101
Bloom syndrome protein isoform 1100010
peripheral myelin protein 22110011
survival motor neuron protein isoform d9009
muscleblind-like protein 1 isoform 14004
ATP-binding cassette sub-family C member 3014014
Multidrug resistance-associated protein 4014016
Carbonic anhydrase0101
Solute carrier family 22 member 60303
Carbonic anhydrase 120318
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump024024
Glycogen phosphorylase, muscle form0101
Carbonic anhydrase 105115
Carbonic anhydrase 205215
Carbonic anhydrase 20202
Carbonic anhydrase 30318
Cathepsin B0101
Cytochrome P450 3A40619
Steryl-sulfatase0101
5-hydroxytryptamine receptor 2C0607
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80101
Cytochrome P450 2D60516
Cytochrome P450 2A60202
Cytochrome P450 2C9 08111
5-hydroxytryptamine receptor 2A0617
Androgen receptor0404
Translocator protein0202
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60112
Carbonic anhydrase 40317
Carbonic anhydrase 60317
Carbonic anhydrase 5A, mitochondrial0101
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40001
Endochitinase0101
5-hydroxytryptamine receptor 2B0404
Delta-type opioid receptor0101
Cytochrome P450 2C190314
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Carbonic anhydrase 5A, mitochondrial0318
Carbonic anhydrase0103
Kappa-type opioid receptor0101
Carbonic anhydrase 70317
Carbonic anhydrase0101
D(1A) dopamine receptor0101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0103
D(2) dopamine receptor0303
Cholinesterase0202
Carbonic anhydrase 0101
Mu-type opioid receptor0101
Fatty-acid amide hydrolase 10202
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0418
Squalene synthase0101
Neuronal acetylcholine receptor subunit alpha-70101
Carbonic anhydrase 90419
Carbonic anhydrase0202
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0103
Carbonic anhydrase 30101
Carbonic anhydrase0104
Carbonic anhydrase0104
Carbonic anhydrase 0101
Sigma intracellular receptor 20101
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10202
Renin0101
Carbonic anhydrase 0103
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130215
Canalicular multispecific organic anion transporter 1014014
Carbonic anhydrase 40305
Carbonic anhydrase 150205
Acidic mammalian chitinase0101
Carbonic anhydrase 130306
Carbonic anhydrase 70101
Carbonic anhydrase 0101
Carbonic anhydrase 140318
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0318
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE130013
Alanine racemase, biosynthetic0001
5-hydroxytryptamine receptor 1D0317
Glutamate receptor ionotropic, NMDA 1 0518
Proton-coupled amino acid transporter 10303
Adenosine deaminase0001
USP1 protein, partial100010
ATAD5 protein, partial100010
D(1A) dopamine receptor2002
neuropeptide S receptor isoform A3003
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0022
NFKB1 protein, partial3003
GLS protein8008
alpha-galactosidase3003
cytochrome P450 2C19 precursor4004
chromobox protein homolog 1140014
flap endonuclease 19009
DNA polymerase iota isoform a (long)6006
muscarinic acetylcholine receptor M16006
lethal factor (plasmid)5005
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30202
ATP-dependent phosphofructokinase8008
regulator of G-protein signaling 44004
67.9K protein4004
Gamma-aminobutyric acid type B receptor subunit 20213
Gamma-aminobutyric acid type B receptor subunit 20202
Gamma-aminobutyric acid type B receptor subunit 10213
Gamma-aminobutyric acid type B receptor subunit 10101
DNA polymerase kappa isoform 16006
Beta-2 adrenergic receptor0213
Beta-1 adrenergic receptor0112
Beta-3 adrenergic receptor0213
Beta-1 adrenergic receptor0101
thyroid stimulating hormone receptor8008
Nuclear receptor ROR-gamma4116
interleukin 83003
progesterone receptor130013
bromodomain adjacent to zinc finger domain 2B5005
IDH19009
nuclear receptor subfamily 1, group I, member 22002
cellular tumor antigen p53 isoform a3003
Nuclear hormone receptor family member daf-120011
nuclear factor erythroid 2-related factor 2 isoform 29009
serine/threonine-protein kinase mTOR isoform 13003
oxysterols receptor LXR-beta isoform 10011
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
Thymidine kinase, cytosolic0101
Thymidine phosphorylase0001
Thymidylate kinase0101
Spike glycoprotein5005
Thymidine kinase0001
Thymidylate kinase0101
ATPase family AAA domain-containing protein 5120012
Ataxin-2120012
Potassium channel subfamily K member 30303
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20112
Potassium channel subfamily K member 90101
Chain A, 2-oxoglutarate Oxygenase100010
15-lipoxygenase, partial3003
apical membrane antigen 1, AMA12002
EWS/FLI fusion protein110011
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
Matrix metalloproteinase-90101
Disintegrin and metalloproteinase domain-containing protein 171001
acetylcholinesterase8008
Vpr4004
Bile salt export pump0505
Albumin0022
Major prion protein0011
Sodium channel protein type 1 subunit alpha0303
Sodium channel protein type 2 subunit alpha0404
Sodium channel protein type 3 subunit alpha0303
UDP-glucuronosyltransferase 2B70306
Sodium channel protein type 4 subunit alpha0305
Cytochrome P450 2J20404
Potassium voltage-gated channel subfamily H member 20909
Sodium channel protein type 9 subunit alpha0404
Frizzled-80011
P2X purinoceptor 40101
Chain A, Ferritin light chain7007
estrogen receptor 2 (ER beta)100010
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
thyrotropin-releasing hormone receptor3003
vitamin D3 receptor isoform VDRA7007
nuclear receptor ROR-gamma isoform 17007
Caspase-20011
Inositol monophosphatase 14004
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Amyloid-beta precursor protein1304
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10101
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Gamma-aminobutyric acid receptor subunit gamma-20202
D0101
5-hydroxytryptamine receptor 1A0617
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Liver carboxylesterase 10102
Sodium-dependent dopamine transporter0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0202
Gamma-aminobutyric acid receptor subunit beta-30202
5-hydroxytryptamine receptor 1B0303
5-hydroxytryptamine receptor 1D0213
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50202
Sodium-dependent serotonin transporter0404
5-hydroxytryptamine receptor 7 0202
Gamma-aminobutyric acid receptor subunit alpha-30202
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0202
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit epsilon0202
Glutamate receptor ionotropic, NMDA 2A 0316
Glutamate receptor ionotropic, NMDA 2C0316
Sodium-dependent dopamine transporter 0505
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60202
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0316
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10202
Glutamate receptor ionotropic, NMDA 3B0316
Sigma non-opioid intracellular receptor 10707
Gamma-aminobutyric acid receptor subunit gamma-30202
5-hydroxytryptamine receptor 3B0202
Leukotriene B4 receptor 20101
Glutamate receptor ionotropic, NMDA 3A0316
Gamma-aminobutyric acid receptor subunit theta0202
Transporter0202
Deoxycytidine kinase0001
Aldo-keto reductase family 1 member B100101
UDP-glucuronosyltransferase 1A90103
Prostaglandin G/H synthase 1 0202
Transient receptor potential cation channel subfamily A member 10011
Dihydrofolate reductase0607
Cytochrome c oxidase subunit 20101
Fatty acid-binding protein, liver0202
Transthyretin0115
Albumin0235
Prostaglandin G/H synthase 10303
Interleukin-80101
Calcium/calmodulin-dependent protein kinase type II subunit alpha0101
Fatty acid-binding protein, intestinal0101
Aldo-keto reductase family 1 member B10303
UDP-glucuronosyltransferase 1-60304
UDP-glucuronosyltransferase 1A1 0404
UDP-glucuronosyltransferase 1A40202
Prostaglandin G/H synthase 10404
Sodium- and chloride-dependent GABA transporter 10101
C-X-C chemokine receptor type 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Prostaglandin G/H synthase 20404
Prostaglandin G/H synthase 2 0203
UDP-glucuronosyltransferase 1A30001
UDP-glucuronosyltransferase 2B10 0202
Sodium- and chloride-dependent betaine transporter0101
Prostaglandin G/H synthase 20303
Prostaglandin G/H synthase 20101
Solute carrier family 22 member 60305
Prostaglandin G/H synthase 1 0203
Multidrug and toxin extrusion protein 10303
P2Y purinoceptor 120101
UDP-glucuronosyltransferase 1A70101
UDP-glucuronosyltransferase 1A100101
Fumarate hydratase5005
G9009
polyprotein5005
Caspase-73003
caspase-33003
Interferon beta110011
HLA class I histocompatibility antigen, B alpha chain 9009
Mitogen-activated protein kinase 140101
Inositol hexakisphosphate kinase 19009
cytochrome P450 2C9, partial9009
ORF730011
chaperonin-containing TCP-1 beta subunit homolog3003
Smad32002
ubiquitin-conjugating enzyme E2 N0101
protein AF-9 isoform a0002
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
5-hydroxytryptamine receptor 40202
Epidermal growth factor receptor0202
Estrogen receptor0404
Receptor tyrosine-protein kinase erbB-20101
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Muscarinic acetylcholine receptor M50202
Alpha-2A adrenergic receptor0202
Muscarinic acetylcholine receptor M10202
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Substance-K receptor0202
5-hydroxytryptamine receptor 2A0516
5-hydroxytryptamine receptor 2C0404
C-8 sterol isomerase0101
D(3) dopamine receptor0303
Alpha-synuclein3104
5-hydroxytryptamine receptor 2B0505
5-hydroxytryptamine receptor 60303
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
Hsf1 protein0011
transcriptional regulator ERG isoform 33003
Taste receptor type 2 member 380001
Chain A, Uracil Phosphoribosyltransferase0101
endonuclease IV2002
Skn7p0001
Thrombopoietin1001
nonstructural protein 13003
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
huntingtin isoform 22002
Solute carrier family 22 member 80001
Thymidylate synthase0404
Aromatase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
Chain A, Dihydrofolate reductase0011
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
acid sphingomyelinase2002
glucocerebrosidase1001
lysosomal alpha-glucosidase preproprotein2002
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 15005
DNA polymerase beta6006
Thymidylate synthase0404
Dihydrofolate reductase0235
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30103
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Smoothened homolog0112
Sonic hedgehog protein0102
Sonic hedgehog protein0101
Smoothened homolog0224
Broad substrate specificity ATP-binding cassette transporter ABCG20102
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0506
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
Integrin beta-32013
Integrin alpha-IIb2013
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0003
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Chain A, HISTIDINE-BINDING PROTEIN0011
Plasma kallikrein0002
Histidine-binding periplasmic protein0011
Large neutral amino acids transporter small subunit 10202
Glutaminyl-peptide cyclotransferase0101
Glycogen synthase kinase-3 alpha0101
Glycogen synthase kinase-3 beta0101
Protein cereblon0416
cytochrome P450 2D67007
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
7,8-dihydro-8-oxoguanine triphosphatase0101
Toll-like receptor 80011
Toll-like receptor 70011
histone deacetylase 9 isoform 32002
cytochrome P450 2D6 isoform 13003
importin subunit beta-1 isoform 12002
snurportin-12002
GTP-binding nuclear protein Ran isoform 11001
Cytochrome P450 1A10202
Cytochrome P450 1B10101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 5 subunit alpha0202
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Sodium channel protein type 3 subunit alpha0303
5-hydroxytryptamine receptor 1A0314
D(2) dopamine receptor0202
D(4) dopamine receptor0101
D(1B) dopamine receptor0101
Catechol O-methyltransferase0101
5-hydroxytryptamine receptor 1E0202
5-hydroxytryptamine receptor 70202
Histamine H1 receptor0101
5-hydroxytryptamine receptor 5A0202
D0101
Sodium-dependent dopamine transporter0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast0101
potassium voltage-gated channel subfamily H member 2 isoform d3003
PPM1D protein2002
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX121001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase eta isoform 13003
transactivating tegument protein VP16 [Human herpesvirus 1]0101
M-phase phosphoprotein 83003
caspase-1 isoform alpha precursor1001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase 0202
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Bifunctional dihydrofolate reductase-thymidylate synthase0101
High mobility group protein B10022
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Kappa-type opioid receptor0101
Reduced folate transporter0202
6-phosphogluconate dehydrogenase, decarboxylating0101
Caspase-71001
Dihydrofolate reductase0101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
TAR DNA-binding protein 433003
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80203
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Solute carrier organic anion transporter family member 1B30001
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Chain E, Fibrin beta chain0101
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
lens epithelium-derived growth factor p750101
Caspase 6, apoptosis-related cysteine peptidase0001
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase4004
hypothetical protein, conserved1001
isocitrate dehydrogenase 1, partial1001
luciferase1001
serine-protein kinase ATM isoform a1001
neutrophil cytosol factor 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
caspase-9 isoform alpha precursor0101
pyruvate kinase PKM isoform a1001
caspase-3 isoform a preproprotein0101
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
DNA repair protein RAD52 homolog isoform a0001
Glutathione reductase0101
Glycoprotein hormones alpha chain1001
Albumin0001
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Amine oxidase [flavin-containing] A0101
Alpha-1D adrenergic receptor0303
Cruzipain0101
Guanine nucleotide-binding protein G2002
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Zinc finger protein mex-50011
phosphoglycerate kinase1001
Solute carrier family 22 member 1 0102
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10101
Chain A, Cruzipain2002
Polyunsaturated fatty acid 5-lipoxygenase0103
Hormone-sensitive lipase0101
Aldo-keto reductase family 1 member C40101
Caspase-10101
Aldo-keto reductase family 1 member C30101
Caspase-30101
Caspase-40101
Caspase-50101
Aldo-keto reductase family 1 member C2 0101
Caspase-90101
Aldo-keto reductase family 1 member C10101
STE240001
CAAX prenyl protease0001
streptokinase A precursor0011
Trypsin0001
DNA gyrase subunit A0102
DNA gyrase subunit B0102
DNA gyrase subunit B0102
DNA gyrase subunit A0102
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0213
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Cystathionine gamma-lyase0202
Succinyl-diaminopimelate desuccinylase0101
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0202
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
Gamma-aminobutyric acid 0101
cytochrome P450 2C9 precursor2002
atrial natriuretic peptide receptor 1 precursor1001
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0112
Aldo-keto reductase family 1 member B10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Histamine H2 receptor3003
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Voltage-dependent L-type calcium channel subunit alpha-1D 0112
Voltage-dependent L-type calcium channel subunit alpha-1S0112
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
luciferase0001
Glucocorticoid receptor0218
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10202
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Histamine H1 receptor0011
Nociceptin receptor0011
Estrogen receptor beta0202
atrial natriuretic peptide receptor 2 precursor1001
ras-related protein Rab-9A1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Aldehyde oxidase0101
Aldehyde oxidase 1 0202
Glutamate 5-kinase0001
Angiotensin-converting enzyme 0101
Neutral amino acid transporter A0202
Neutral amino acid transporter B(0)0202
Amino acid transporter0202
heat shock protein HSP 90-alpha isoform 20001
heat shock protein 90, putative0001
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, Lysr-type Regulatory Protein0011
Chain A, 146aa long hypothetical transcriptional regulator0011
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Chain B, Anthranilate phosphoribosyltransferase0101
Chain C, Anthranilate phosphoribosyltransferase0101
Chain A, Anthranilate phosphoribosyltransferase0101
Anthranilate phosphoribosyltransferase0101
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Polyphenol oxidase 20102
5'-AMP-activated protein kinase subunit beta-20001
Polymerase acidic protein0011
Stromelysin-10112
Tyrosine-protein phosphatase YopH0101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Estrogen receptor0001
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Acetylcholinesterase0101
Pyruvate kinase PKM0011
5-hydroxytryptamine receptor 3E0101
5-hydroxytryptamine receptor 3B0101
Carboxypeptidase M0101
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 1F0213
Alpha-1A adrenergic receptor0101
5-hydroxytryptamine receptor 3A0101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1A0101
5-hydroxytryptamine receptor 3D0101
5-hydroxytryptamine receptor 3C0101
5-hydroxytryptamine receptor 1B0101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Thymidine phosphorylase0101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
serine/threonine-protein kinase PLK11001
Solute carrier organic anion transporter family member 1A40001
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 1A50001
Rap guanine nucleotide exchange factor 31001
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0246
Peroxisome proliferator-activated receptor gamma0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Bile acid receptor0101
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10001
Chain A, Nuclear Receptor ROR-beta0101
Parkin1001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Substance-P receptor0101
Tryptophan 2,3-dioxygenase0102
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Tryprostatin B synthase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Monocarboxylate transporter 100001
Phospholipase A-2-activating protein0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Solute carrier family 2, facilitated glucose transporter member 90112
Guanine deaminase0101
Cocaine esterase0101
Histone deacetylase 30202
Tissue factor0101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]