Page last updated: 2024-09-28

Congenital Cystic Adenomatoid Malformation

This type is microcystic, characterized by multiple cysts of 0.5 to 2.5 cm.

Synonyms(12)

Synonym
Congenital Cystic Adenomatoid Malformation, Type 1
Congenital Cystic Adenomatoid Malformation, Type III
Congenital Cystic Adenomatoid Malformation, Type 2
Congenital Cystic Adenomatoid Malformation, Type 3
Congenital Cystic Adenomatoid Malformation, Type I
Cystic Adenomatoid Malformation of Lung
Cystic Adenomatoid Malformation of Lung, Congenital
Congenital Cystic Adenomatoid Malformation, Type II
Lung Malformation, Cystic Adenomatoid, Congenital
Lung Malformation, Congenital Cystic Adenomatoid
Congenital Cystic Adenomatoid Malformation
Congenital Cystic Adenomatoid Malformation of Lung

Research Excerpts

Research

Studies (47)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's6 (12.77)12.5806
2000's17 (36.17)18.1394
2010's19 (40.43)28.8240
2020's5 (10.64)9.53
DrugIndicatedRelationship StrengthStudiesTrials
cytosine0low10
ethanolamine0low10
bupivacaine0low10
valproic acid0low10
fentanyl0low30
guaifenesin0low10
indomethacin0low10
iohexol0low10
iopromide0low10
propofol0low10
sevoflurane0low30
betamethasone0low160
vancomycin0low10
barium sulfate0low10
4-chlorophenyl methyl sulfide0low10
vecuronium bromide0low10
cidofovir anhydrous0low10
remifentanil0low30
xenon radioisotopes0low10
fluorodeoxyglucose f180low10
organophosphonates0low10
elastin0low10
rocuronium0low10
clindamycin0low10
misoprostol0low10
ethamolin0low10
neurotensin0low10
piperidines0low20
gastrin-releasing peptide0low10
cyclin d10low10
adrenomedullin0low10
exudates0low10
sildenafil citrate0low10

Protein Targets (380)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
nuclear receptor subfamily 1, group I, member 36006
thyroid hormone receptor beta isoform a5005
Cellular tumor antigen p537007
pregnane X receptor3003
GLI family zinc finger 37007
AR protein7007
progesterone receptor5005
cytochrome P450 family 3 subfamily A polypeptide 47007
glucocorticoid receptor [Homo sapiens]7007
estrogen-related nuclear receptor alpha8008
farnesoid X nuclear receptor7007
pregnane X nuclear receptor7007
estrogen nuclear receptor alpha120012
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
IDH13003
aryl hydrocarbon receptor3003
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
nuclear receptor subfamily 1, group I, member 22002
nuclear factor erythroid 2-related factor 2 isoform 22002
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 17007
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40707
Voltage-dependent calcium channel gamma-2 subunit4004
Bile salt export pump0909
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Glutamate receptor 24004
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
Canalicular multispecific organic anion transporter 10707
ORF730011
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20011
Potassium channel subfamily K member 90101
Thymidine kinase 0101
Solute carrier family 22 member 60102
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Thymidine kinase0001
Solute carrier family 22 member 60203
Protein-arginine deiminase type-40101
RAR-related orphan receptor gamma5005
geminin6006
Deoxycytidine kinase0001
aldehyde dehydrogenase 1 family, member A13003
thyroid stimulating hormone receptor2002
estrogen receptor 2 (ER beta)3003
retinoic acid nuclear receptor alpha variant 15005
retinoid X nuclear receptor alpha3003
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma5005
thyroid stimulating hormone receptor3003
activating transcription factor 63003
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
v-jun sarcoma virus 17 oncogene homolog (avian)2002
Histone H2A.x2002
thyroid hormone receptor beta isoform 24004
heat shock protein beta-14004
Glutaminyl-peptide cyclotransferase0101
Luciferase4004
TDP1 protein5005
euchromatic histone-lysine N-methyltransferase 26006
potassium voltage-gated channel subfamily H member 2 isoform d4004
Solute carrier family 22 member 1 0101
Nuclear receptor subfamily 1 group I member 20011
ATP-dependent translocase ABCB10202
D(2) dopamine receptor0101
Amine oxidase [flavin-containing] A0101
D(4) dopamine receptor0101
Amine oxidase [flavin-containing] B0101
Delta-type opioid receptor0202
Delta-type opioid receptor0202
Mu-type opioid receptor0314
Kappa-type opioid receptor0101
Histamine H1 receptor0101
Mu-type opioid receptor0213
D(3) dopamine receptor0101
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Potassium voltage-gated channel subfamily H member 20202
Sigma non-opioid intracellular receptor 10404
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10101
SMAD family member 22002
SMAD family member 32002
flap endonuclease 11001
Rap guanine nucleotide exchange factor 31001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, membrane-associated prostaglandin E synthase-20101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, 2-oxoglutarate Oxygenase3003
Chain A, Cruzipain3003
interleukin 81001
hypoxia-inducible factor 1 alpha subunit2002
Microtubule-associated protein tau3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
EWS/FLI fusion protein1001
G5005
67.9K protein1001
glucocerebrosidase1001
Parkin2002
bromodomain adjacent to zinc finger domain 2B2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
cytochrome P450 2D6 isoform 11001
peripheral myelin protein 22 isoform 11001
cytochrome P450 2C9 precursor1001
vitamin D3 receptor isoform VDRA3003
ras-related protein Rab-9A1001
serine/threonine-protein kinase mTOR isoform 11001
DNA polymerase iota isoform a (long)2002
nuclear receptor ROR-gamma isoform 13003
DNA polymerase kappa isoform 12002
M-phase phosphoprotein 82002
lamin isoform A-delta104004
neuropeptide S receptor isoform A2002
Prostaglandin-H2 D-isomerase0101
Prostaglandin E synthase0101
Prostaglandin G/H synthase 1 0102
Prostaglandin G/H synthase 2 0102
3',5'-cyclic-AMP phosphodiesterase 0101
Solute carrier organic anion transporter family member 2B1 0202
Cytochrome c oxidase subunit 20101
Epidermal growth factor receptor0101
Phospholipase A2, major isoenzyme0101
Interferon beta5005
HLA class I histocompatibility antigen, B alpha chain 5005
Albumin0123
Prostaglandin G/H synthase 10203
Procathepsin L0101
Neuronal acetylcholine receptor subunit alpha-41102
Interleukin-80101
Androgen receptor0011
Neuronal acetylcholine receptor subunit beta-21102
Polyunsaturated fatty acid 5-lipoxygenase0102
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member B10101
Aldo-keto reductase family 1 member C40101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 10202
Sodium-dependent dopamine transporter0101
Sodium- and chloride-dependent GABA transporter 10202
Thromboxane-A synthase 0101
Adenosine receptor A10101
Serum paraoxonase/arylesterase 10101
Indoleamine 2,3-dioxygenase 10202
Caspase-10001
Nitric oxide synthase, inducible0101
Adenosine receptor A2a0101
Substance-P receptor0101
Prostaglandin E2 receptor EP3 subtype0101
Sodium- and chloride-dependent GABA transporter 20202
Sodium- and chloride-dependent GABA transporter 30202
Prostaglandin E2 receptor EP4 subtype0101
Multidrug resistance-associated protein 1 0101
Bifunctional epoxide hydrolase 20101
Prostaglandin G/H synthase 20213
Prostaglandin G/H synthase 2 0101
Prostaglandin E2 receptor EP1 subtype0101
Peroxisome proliferator-activated receptor gamma0011
Aldo-keto reductase family 1 member C30202
Histamine H2 receptor1001
Sodium- and chloride-dependent betaine transporter0202
C-X-C chemokine receptor type 30101
Nuclear receptor ROR-gamma2114
Aldo-keto reductase family 1 member C2 0101
Spike glycoprotein4004
Guanine nucleotide-binding protein G1001
Prostaglandin D2 receptor 0202
Solute carrier organic anion transporter family member 1A30101
Prostaglandin G/H synthase 20202
Lactoylglutathione lyase0101
Aldo-keto reductase family 1 member C10101
Prostaglandin G/H synthase 20102
Uracil nucleotide/cysteinyl leukotriene receptor0101
Solute carrier family 22 member 70001
Sigma intracellular receptor 20101
Prostaglandin E2 receptor EP2 subtype0101
Rho-associated protein kinase 20101
Prostaglandin G/H synthase 1 0101
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 80101
Inositol hexakisphosphate kinase 15005
Multidrug and toxin extrusion protein 10202
Dehydrogenase/reductase SDR family member 90101
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30202
Cytosolic phospholipase A2 gamma0101
Prostaglandin D2 receptor 20112
Solute carrier organic anion transporter family member 1B10202
cytochrome P450 2C9, partial5005
ATAD5 protein, partial2002
USP1 protein, partial3003
importin subunit beta-1 isoform 11001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
thioredoxin glutathione reductase2002
cytochrome P450 2D62002
DNA polymerase beta1001
peripheral myelin protein 224004
ATPase family AAA domain-containing protein 53003
Ataxin-23003
Neurotensin receptor type 10011
Neurotensin receptor type 20113
Myelin basic protein0011
Neurotensin receptor type 10112
Neurotensin receptor type 10225
Neurotensin receptor type 20213
Sortilin0101
glp-1 receptor, partial1001
thioredoxin reductase2002
GALC protein1001
beta-2 adrenergic receptor1001
Bloom syndrome protein isoform 13003
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
chromobox protein homolog 12002
Vpr1001
5-hydroxytryptamine receptor 2A0011
Chain A, Ferritin light chain2002
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
GLS protein2002
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
D(1A) dopamine receptor1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
cytochrome P450 3A4 isoform 12002
muscarinic acetylcholine receptor M11001
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit pi2114
UDP-glucuronosyltransferase 1A90002
5-hydroxytryptamine receptor 40202
Carbonic anhydrase 10102
Carbonic anhydrase 20102
Aldo-keto reductase family 1 member B10303
Gamma-aminobutyric acid receptor subunit alpha-10001
Gamma-aminobutyric acid receptor subunit beta-10001
Gamma-aminobutyric acid receptor subunit alpha-20001
Gamma-aminobutyric acid receptor subunit alpha-30001
Polyunsaturated fatty acid lipoxygenase ALOX150101
Gamma-aminobutyric acid receptor subunit alpha-10112
Gamma-aminobutyric acid receptor subunit beta-12114
Gamma-aminobutyric acid receptor subunit beta-10011
Gamma-aminobutyric acid receptor subunit delta2114
Gamma-aminobutyric acid receptor subunit gamma-20112
Gamma-aminobutyric acid receptor subunit gamma-22114
Gamma-aminobutyric acid receptor subunit alpha-52114
Gamma-aminobutyric acid receptor subunit alpha-32114
Gamma-aminobutyric acid receptor subunit alpha-40001
Gamma-aminobutyric acid receptor subunit gamma-20001
Gamma-aminobutyric acid receptor subunit gamma-12114
Gamma-aminobutyric acid receptor subunit alpha-22114
Sodium-dependent noradrenaline transporter 0202
5-hydroxytryptamine receptor 2C0202
Gamma-aminobutyric acid receptor subunit alpha-42114
Gamma-aminobutyric acid receptor subunit beta-30112
Gamma-aminobutyric acid receptor subunit gamma-32114
Gamma-aminobutyric acid receptor subunit alpha-62114
Gamma-aminobutyric acid receptor subunit alpha-50011
Gamma-aminobutyric acid receptor subunit alpha-30011
5-hydroxytryptamine receptor 2B0404
Gamma-aminobutyric acid receptor subunit alpha-20011
Gamma-aminobutyric acid receptor subunit beta-20011
Gamma-aminobutyric acid receptor subunit alpha-40011
Gamma-aminobutyric acid receptor subunit alpha-12114
Gamma-aminobutyric acid receptor subunit beta-32114
Gamma-aminobutyric acid receptor subunit beta-22114
Fatty-acid amide hydrolase 10101
Gamma-aminobutyric acid receptor subunit alpha-60011
GABA theta subunit2114
Gamma-aminobutyric acid receptor subunit epsilon2114
UDP-glucuronosyltransferase 1A80001
Carbonic anhydrase 120001
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Carbonic anhydrase 30001
Carbonic anhydrase 40001
Carbonic anhydrase 60001
Carbonic anhydrase 5A, mitochondrial0001
Carbonic anhydrase 70001
Carbonic anhydrase 90001
Carbonic anhydrase 130001
Carbonic anhydrase 140001
Carbonic anhydrase 5B, mitochondrial0001
Chain A, Nuclear Receptor ROR-beta0101
Chain A, Beta-lactamase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
phosphopantetheinyl transferase1001
regulator of G-protein signaling 41001
nonstructural protein 11001
thyrotropin-releasing hormone receptor1001
Caspase-71001
caspase-31001
survival motor neuron protein isoform d1001
histone acetyltransferase KAT2A isoform 11001
Ornithine decarboxylase0001
Amyloid-beta precursor protein0101
Cytochrome P450 1A20011
Cytochrome P450 3A40011
Ornithine decarboxylase0001
60 kDa chaperonin0101
Adenosine receptor A30202
Retinoic acid receptor alpha0227
Cytochrome P450 2D60011
60 kDa heat shock protein, mitochondrial0202
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Cytochrome P450 2C9 0011
Retinoic acid receptor gamma 0227
Alpha-1B adrenergic receptor0303
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
5-hydroxytryptamine receptor 1A0101
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Alpha-1D adrenergic receptor0202
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Cytochrome P450 2C190011
Nuclear receptor ROR-alpha0101
Alpha-synuclein0101
Cellular retinoic acid-binding protein 10102
Alpha-1A adrenergic receptor0303
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0202
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0202
60 kDa chaperonin 0202
10 kDa chaperonin 0202
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
ATP-dependent phosphofructokinase1001
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Cocaine esterase0101
Histone deacetylase 30202
Bile salt export pump0101
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
Alpha-2A adrenergic receptor0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Sodium-dependent serotonin transporter0101
D-alanyl-D-alanine dipeptidase0101
Transporter0101
acetylcholinesterase1001
Solute carrier family 22 member 20101
Multidrug and toxin extrusion protein 20101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]