Page last updated: 2024-09-28

Ciliary Dyskinesia

Synonyms(4)

Synonym
Ciliary Dyskinesia, Primary
Ciliary Dyskinesia
Immotile Cilia Syndrome
Primary Ciliary Dyskinesia

Research Excerpts

Overview

ExcerptReference
"The immotile cilia syndrome is an inherited disorder characterized by inappropriate motility of the cilia."( Byloos, J; Clement, P; Delree, M; Ramet, J; Sacre, L, 1986)
"Primary ciliary dyskinesia is a genetic disorder causing dysfunctional motility of cilia and impaired mucociliary clearance, resulting in a myriad of clinical manifestations including recurrent sinopulmonary disease, laterality defects and infertility."( Ferkol, T; Lie, H, 2007)

Treatment

ExcerptReference
"In primary ciliary dyskinesia (PCD), chest physiotherapy for airway clearance is essential."( Bush, A; Heather, S; Phillips, GE; Thomas, S, 1998)
"Treatment of primary ciliary dyskinesia pulmonary exacerbations resulted in an increase in sputum nitric oxide (NO) metabolites and decrease in neutrophilic inflammation."( Dell, S; Grasemann, H; McDonald, N; Ratjen, F; Waters, V; Yuan, XZ, 2022)

Research

Studies (195)

TimeframeStudies, This Condition (%)All Conditions %
pre-199047 (24.10)23.3326
1990's43 (22.05)12.5806
2000's40 (20.51)18.1394
2010's38 (19.49)28.8240
2020's27 (13.85)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbon monoxide0low10
chlorine0low20
iodine0low40
phytic acid0low10
inositol0low20
sulfur dioxide0low20
menthol0low10
3-aminobenzamide0low10
albuterol0medium31
ambroxol0low10
theophylline0low20
bromhexine0low10
platinum tetrachloride0low10
clenbuterol0low10
pentetic acid0low20
valproic acid0low10
enflurane0low10
gentamicin0low10
guaifenesin0medium311
isoflurane0low10
nifedipine0low10
omeprazole0low10
pentoxifylline0low10
procaterol0low10
propidium0medium11
saccharin0medium121
sulforaphane0low10
terbutaline0low20
aminopyrine0low10
uridine diphosphate0medium11
methacholine chloride0low10
uridine triphosphate0low20
chloroform0low10
mannitol0low10
arginine0medium51
phencyclidine0low10
methylprednisolone0low10
pyocyanine0low10
2-naphthylamine0low10
pyrrolidonecarboxylic acid0low10
thiophenes0medium11
acridines0low10
nitroblue tetrazolium0low10
thiazolidines0low10
gentian violet0low10
acetylcysteine0medium21
fucose0low10
technetium0low30
helium0low10
phenyl acetate0low10
glutamic acid0low10
tobramycin0low10
vanadates0low10
10,10'-dimethyl-9,9'-biacridinium0low10
2-oxothiazolidine-4-carboxylic acid0low10
erdosteine0medium11
xenon radioisotopes0low10
laurdan0low10
technetium tc 99m pentetate0low40
atropine0low10
povidone-iodine0low10
n-acetylneuraminic acid0low10
mevalonic acid0low10
oxytocin0low10
arachidonic acid0low10
zithromax0medium62
sorbic acid0low10
cotinine0low10
tamoxifen0low10
lithium0low10
nitrogen dioxide0low10
freedom0low10
nitinol0low10
leukotriene b40low10
arachidonic acid omega-9 hydroperoxide0low10
montelukast0low10
phenylephrine hydrochloride0low220
diphenylhexatriene0low10
cysteine0low10
mevalonolactone0low10
helium-3 atom0low10
chlorhexidine0low10
motilin0low10
glycolipids0low20
interleukin-80low10
transforming growth factor beta0low10
technetium tc 99m sulfur colloid0low40
lewis x antigen0low10
vitamin b 120low10
muramidase0low10
ribosomal protein l7-l120low10
guanosine triphosphate0low10
folic acid0low10
1-hydroxyphenazine0low10
sildenafil citrate0low10

Protein Targets (840)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Putative fructose-1,6-bisphosphate aldolase6006
Chain A, JmjC domain-containing histone demethylation protein 3A7007
Luciferase110011
TDP1 protein200020
Microtubule-associated protein tau100011
thioredoxin glutathione reductase4004
Smad35005
apical membrane antigen 1, AMA14004
aldehyde dehydrogenase 1 family, member A1110011
nonstructural protein 14004
bromodomain adjacent to zinc finger domain 2B6006
euchromatic histone-lysine N-methyltransferase 2210021
lysosomal alpha-glucosidase preproprotein3003
glyceraldehyde-3-phosphate dehydrogenase isoform 11001
flap endonuclease 19009
ras-related protein Rab-9A2002
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase iota isoform a (long)9009
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
nuclear receptor ROR-gamma isoform 1100010
Vpr2002
transient receptor potential cation channel subfamily V member 11001
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
neuropeptide S receptor isoform A1001
Alpha-synuclein4004
Guanine nucleotide-binding protein G4004
TAR DNA-binding protein 437007
Chain A, HADH2 protein8008
Chain B, HADH2 protein8008
thioredoxin reductase120012
ClpP2002
pregnane X receptor7007
RAR-related orphan receptor gamma190019
SMAD family member 26006
SMAD family member 36006
AR protein210021
estrogen receptor 2 (ER beta)9009
nuclear receptor subfamily 1, group I, member 3150015
regulator of G-protein signaling 4110011
glucocorticoid receptor [Homo sapiens]180018
retinoic acid nuclear receptor alpha variant 1200020
estrogen-related nuclear receptor alpha230023
pregnane X nuclear receptor130013
estrogen nuclear receptor alpha270027
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a120012
nuclear factor erythroid 2-related factor 2 isoform 26006
thyroid hormone receptor beta isoform 2140014
nuclear factor erythroid 2-related factor 2 isoform 1170017
cytochrome P450 3A4 isoform 19009
Gamma-aminobutyric acid receptor subunit pi9009
Neutrophil cytosol factor 10101
Gamma-aminobutyric acid receptor subunit beta-19009
Gamma-aminobutyric acid receptor subunit delta9009
Gamma-aminobutyric acid receptor subunit gamma-29009
Gamma-aminobutyric acid receptor subunit alpha-59009
Gamma-aminobutyric acid receptor subunit alpha-39009
Gamma-aminobutyric acid receptor subunit gamma-19009
Gamma-aminobutyric acid receptor subunit alpha-29009
Gamma-aminobutyric acid receptor subunit alpha-49009
Gamma-aminobutyric acid receptor subunit gamma-39009
Gamma-aminobutyric acid receptor subunit alpha-69009
Nuclear receptor ROR-gamma100010
Gamma-aminobutyric acid receptor subunit alpha-191010
Gamma-aminobutyric acid receptor subunit beta-39009
Gamma-aminobutyric acid receptor subunit beta-29009
GABA theta subunit9009
Gamma-aminobutyric acid receptor subunit epsilon9009
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE130013
Chain A, 2-oxoglutarate Oxygenase130013
Chain A, Ferritin light chain6006
Chain A, Cruzipain4004
cytochrome P450 2D6 isoform 16006
cytochrome P450 2C9 precursor5005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 18008
lamin isoform A-delta10160016
Poly [ADP-ribose] polymerase 20101
Poly [ADP-ribose] polymerase 10202
Poly [ADP-ribose] polymerase 1 0101
Histamine H2 receptor100011
Transporter0101
ATP-dependent phosphofructokinase100010
Chain A, ATP-DEPENDENT DNA HELICASE Q14004
acetylcholinesterase7007
dopamine D1 receptor2002
15-lipoxygenase, partial5005
phosphopantetheinyl transferase120012
USP1 protein, partial140014
NFKB1 protein, partial4004
Thrombopoietin2002
retinoid X nuclear receptor alpha160016
farnesoid X nuclear receptor9009
vitamin D (1,25- dihydroxyvitamin D3) receptor140014
arylsulfatase A7007
Bloom syndrome protein isoform 19009
D(1A) dopamine receptor3003
thyroid hormone receptor beta isoform a7007
heat shock protein beta-16006
geminin190019
peripheral myelin protein 22120012
survival motor neuron protein isoform d6006
muscarinic acetylcholine receptor M15005
Histone deacetylase 30303
Solute carrier family 22 member 60202
Histone deacetylase 40303
Histone deacetylase 10303
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
Ataxin-29009
Histone deacetylase 80303
Histone deacetylase 60303
Histone deacetylase 90303
Histone deacetylase 50303
alpha-galactosidase3003
DNA topoisomerase 2-alpha0001
Acetylcholinesterase0505
glp-1 receptor, partial8008
GLS protein8008
NPYLR7B0011
thyroid stimulating hormone receptor9009
ATP-binding cassette sub-family C member 3013013
Multidrug resistance-associated protein 4013014
Bile salt export pump017017
Beta-2 adrenergic receptor07613
Beta-1 adrenergic receptor0437
60 kDa chaperonin0303
60 kDa heat shock protein, mitochondrial0303
Beta-3 adrenergic receptor0426
Delta-type opioid receptor0124
10 kDa heat shock protein, mitochondrial0303
Thiosulfate sulfurtransferase0303
Beta-2 adrenergic receptor 0039
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Beta-2 adrenergic receptor0135
Canalicular multispecific organic anion transporter 1013013
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)8008
cytochrome P450 2D67007
glucocerebrosidase6006
chromobox protein homolog 19009
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Rap guanine nucleotide exchange factor 32002
Lysosomal acid glucosylceramidase0112
Cytochrome P450 2D60303
Sodium-dependent serotonin transporter0606
interleukin 85005
GLI family zinc finger 3190019
thyroid stimulating hormone receptor100010
cytochrome P450 family 3 subfamily A polypeptide 4100010
G7007
peroxisome proliferator-activated receptor delta110011
activating transcription factor 69009
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
v-jun sarcoma virus 17 oncogene homolog (avian)100010
histone deacetylase 9 isoform 33003
Voltage-dependent calcium channel gamma-2 subunit8008
Interferon beta9009
HLA class I histocompatibility antigen, B alpha chain 7007
Glutamate receptor 282111
Nicotinate phosphoribosyltransferase0202
Inositol hexakisphosphate kinase 17007
cytochrome P450 2C9, partial7007
ORF730011
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN0011
Chain A, SERUM ALBUMIN0011
Chain A, SERUM ALBUMIN0011
Chain A, TYROSYL-DNA PHOSPHODIESTERASE9009
Chain A, Beta-lactamase3003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
cellular tumor antigen p53 isoform a5005
vitamin D3 receptor isoform VDRA9009
ubiquitin carboxyl-terminal hydrolase 2 isoform a4004
lethal(3)malignant brain tumor-like protein 1 isoform I2002
DNA polymerase kappa isoform 16006
histone acetyltransferase KAT2A isoform 16006
DNA dC->dU-editing enzyme APOBEC-3G isoform 11001
caspase-1 isoform alpha precursor2002
Fatty-acid amide hydrolase 10101
Polyunsaturated fatty acid lipoxygenase ALOX15B7007
Prostaglandin G/H synthase 1 0102
Trypsin0101
Coagulation factor VII0101
Aromatase0101
Tissue factor0202
Fatty acid-binding protein, adipocyte0112
Prostaglandin G/H synthase 20214
Nuclear receptor subfamily 4 group A member 20011
Calmodulin 0001
Disintegrin and metalloproteinase domain-containing protein 174004
Prostaglandin G/H synthase 20102
Solute carrier organic anion transporter family member 2A10001
Fatty acid-binding protein 50101
Fatty acid-binding protein 50011
Lanosterol 14-alpha demethylase0101
Solute carrier organic anion transporter family member 1B30202
Cytosolic phospholipase A2 gamma0101
Transient receptor potential cation channel subfamily V member 20101
Solute carrier organic anion transporter family member 1B10202
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
cytochrome P450 2C19 precursor6006
lethal factor (plasmid)6006
Cytochrome P450 3A40607
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0102
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
hypothetical protein, conserved4004
EWS/FLI fusion protein3003
Rac1 protein0011
IDH18008
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
Prostaglandin-H2 D-isomerase0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0505
Carbonic anhydrase 10406
Carbonic anhydrase 20406
Fatty acid-binding protein, liver0101
Integrin beta-34116
Myeloperoxidase0101
Prostaglandin G/H synthase 10101
Seed linoleate 13S-lipoxygenase-10101
Integrin alpha-IIb4116
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10304
Adenosine receptor A2a0305
Substance-P receptor0101
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Rho-associated protein kinase 20101
Solute carrier family 22 member 200101
Solute carrier family 22 member 60101
Sigma non-opioid intracellular receptor 10516
Sigma non-opioid intracellular receptor 10213
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0203
5-hydroxytryptamine receptor 40606
Muscarinic acetylcholine receptor M206112
Muscarinic acetylcholine receptor M406111
Muscarinic acetylcholine receptor M10226
Muscarinic acetylcholine receptor M30226
Muscarinic acetylcholine receptor M40226
Muscarinic acetylcholine receptor M50226
Muscarinic acetylcholine receptor M506110
Muscarinic acetylcholine receptor M20227
Muscarinic acetylcholine receptor M108114
Muscarinic acetylcholine receptor M10013
Muscarinic acetylcholine receptor M308112
Alpha-1D adrenergic receptor0606
5-hydroxytryptamine receptor 2C0606
Muscarinic acetylcholine receptor M40113
5-hydroxytryptamine receptor 70101
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0213
Chain A, BCL-2-RELATED PROTEIN A10011
acid sphingomyelinase2002
PAX80001
hypoxia-inducible factor 1 alpha subunit8008
caspase 7, apoptosis-related cysteine protease3003
PINK11001
progesterone receptor100010
67.9K protein5005
Parkin2002
peroxisome proliferator activated receptor gamma9009
heat shock protein 900011
caspase-33003
calcineurin A1, putative0011
Histone H2A.x4004
hepatocyte nuclear factor 4-alpha isoform 20101
perilipin-50202
perilipin-10202
potassium voltage-gated channel subfamily H member 2 isoform d6006
transcriptional regulator ERG isoform 33003
huntingtin isoform 23003
importin subunit beta-1 isoform 11001
mitogen-activated protein kinase 13003
ubiquitin-conjugating enzyme E2 N0202
nuclear factor NF-kappa-B p105 subunit isoform 12002
protein AF-9 isoform a0001
snurportin-11001
melanocortin receptor 40101
CAAX prenyl protease0001
bcl-2-related protein A10101
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0202
glycogen synthase kinase-3 alpha0001
hexokinase HKDC10101
DNA repair protein RAD52 homolog isoform a0001
bcl-2-like protein 11 isoform 10011
Synaptojanin-20101
Solute carrier family 22 member 20101
Synaptojanin-10101
Solute carrier family 22 member 30101
Glutathione reductase, mitochondrial0506
Cellular tumor antigen p53180018
72 kDa type IV collagenase0101
Matrix metalloproteinase-90101
Trypanothione reductase0101
Spike glycoprotein90110
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase0101
Multidrug and toxin extrusion protein 20101
Rap guanine nucleotide exchange factor 41001
Multidrug and toxin extrusion protein 10101
ATPase family AAA domain-containing protein 58008
Spermine oxidase0101
Carbonic anhydrase 40203
Carbonic anhydrase0101
Carbonic anhydrase 150101
5-hydroxytryptamine receptor 1A0404
5-hydroxytryptamine receptor 1B0404
ATAD5 protein, partial3003
GALC protein4004
Cytochrome P450 1A20202
Neuronal acetylcholine receptor subunit alpha-41113
Cytochrome P450 2A60202
Neuronal acetylcholine receptor subunit beta-21113
Cytochrome P450 2A50101
Chain A, Dihydrofolate reductase0011
Thymidylate synthase0202
Thymidylate synthase0101
Dihydrofolate reductase0011
Aldo-keto reductase family 1 member B10101
Folylpolyglutamate synthase, mitochondrial0001
Solute carrier organic anion transporter family member 1A30101
Folylpolyglutamate synthase, mitochondrial0001
Multidrug resistance associated protein0001
Fucose-binding lectin PA-IIL0101
CD209 antigen0202
beta-amyloid peptide, A beta {N-terminal} [human, cerebrospinal fluid, conditioned medium of mixed-brain cell cultures, Peptide Partial, 33 aa]1001
alpha synuclein, partial1001
luciferase1001
thyrotropin-releasing hormone receptor3003
nuclear receptor subfamily 1, group I, member 24004
Caspase-72002
tumor necrosis factor2002
polyunsaturated fatty acid lipoxygenase ALOX122002
caspase-32002
Tyrosine-protein kinase Fyn0303
Alpha-2A adrenergic receptor0606
Adenosine receptor A30909
D(2) dopamine receptor0505
Androgen receptor0606
Alpha-1B adrenergic receptor0909
Alpha-2B adrenergic receptor0404
Alpha-2C adrenergic receptor0404
Substance-K receptor0606
D(1A) dopamine receptor0404
Glutamate receptor ionotropic, kainate 11214
Histamine H2 receptor0404
5-hydroxytryptamine receptor 2A0404
Adenosine receptor A2a07210
Mu-type opioid receptor0404
D(3) dopamine receptor0606
Kappa-type opioid receptor0404
Glutamate receptor ionotropic, kainate 21214
Glutamate receptor ionotropic, kainate 31203
Alpha-1A adrenergic receptor0909
Fatty-acid amide hydrolase 11102
Inositol monophosphatase 16006
Glutamate receptor ionotropic, kainate 41203
Sodium-dependent dopamine transporter 0606
Leukotriene B4 receptor 11204
Glutamate receptor ionotropic, kainate 51203
Leukotriene B4 receptor 21103
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor4004
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0202
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0415
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Glutamate receptor ionotropic, NMDA 2A 0415
Glutamate receptor ionotropic, NMDA 2B0415
Glutamate receptor ionotropic, NMDA 2C0416
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10303
Glutamate receptor ionotropic, NMDA 2A0303
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0303
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0001
Glutamate receptor ionotropic, NMDA 2D0415
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0202
Glutamate receptor ionotropic, NMDA 3B0415
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0415
Chain A, Uracil Phosphoribosyltransferase0011
Chain B, Uracil Phosphoribosyltransferase0011
Chain C, Uracil Phosphoribosyltransferase0011
2-dehydropantoate 2-reductase0011
Ras-related protein Rab-7a0011
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 90202
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Amyloid-beta precursor protein0101
Sodium/myo-inositol cotransporter 20101
Neuronal acetylcholine receptor subunit beta-20101
Neuronal acetylcholine receptor subunit alpha-70101
Transient receptor potential cation channel subfamily A member 10011
Secreted chorismate mutase0101
Transient receptor potential cation channel subfamily M member 80124
Transient receptor potential cation channel subfamily A member 10022
Transient receptor potential cation channel subfamily M member 80011
galanin receptor type 30101
PPM1D protein3003
muscleblind-like protein 1 isoform 12002
Nuclear receptor subfamily 1 group I member 20011
Glucocorticoid receptor0415
Glycine receptor subunit alpha-10404
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Nuclear receptor subfamily 1 group I member 20011
Aldo-keto reductase family 1 member B10505
Cytochrome P450 2C80101
Sodium-dependent noradrenaline transporter 0404
Thromboxane-A synthase 0303
Delta-type opioid receptor0404
5-hydroxytryptamine receptor 2B0404
Uracil nucleotide/cysteinyl leukotriene receptor0101
Mitogen-activated protein kinase 140101
Leukotriene C4 synthase0101
Cysteinyl leukotriene receptor 10101
Cysteinyl leukotriene receptor 20101
Cysteinyl leukotriene receptor 10213
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
Fumarate hydratase2002
polyprotein2002
peripheral myelin protein 22 isoform 13003
atrial natriuretic peptide receptor 2 precursor1001
serine/threonine-protein kinase mTOR isoform 12002
serine/threonine-protein kinase PLK12002
eyes absent homolog 2 isoform a1001
M-phase phosphoprotein 83003
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
Bile salt export pump0202
Potassium channel subfamily K member 20022
ATP-dependent translocase ABCB10415
Cytochrome P450 2C9 0303
Polyunsaturated fatty acid lipoxygenase ALOX150101
Phospholipase A2, membrane associated0001
5-hydroxytryptamine receptor 2A0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Potassium voltage-gated channel subfamily A member 50101
3-oxo-5-alpha-steroid 4-dehydrogenase 1 0101
Platelet-activating factor receptor0001
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Indoleamine 2,3-dioxygenase 10101
Adenosine receptor A10619
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 4 subunit alpha0101
C-C chemokine receptor type 20202
Cytochrome P450 2J20202
Sodium channel protein type 7 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Potassium voltage-gated channel subfamily A member 10101
Potassium voltage-gated channel subfamily H member 20404
C-terminal-binding protein 11001
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0203
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0202
Sodium channel protein type 5 subunit alpha0101
Myosin light chain kinase, smooth muscle0101
Sodium channel protein type 9 subunit alpha0101
Potassium channel subfamily K member 2 0101
Indoleamine 2,3-dioxygenase 20101
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Sodium channel protein type 2 subunit alpha0101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Sodium channel protein type 3 subunit alpha0101
Sodium channel protein type 11 subunit alpha0101
Broad substrate specificity ATP-binding cassette transporter ABCG20202
Sodium channel protein type 8 subunit alpha0101
Sodium channel protein type 10 subunit alpha0101
Mcl-10101
pyruvate kinase PKM isoform a1001
cGMP-specific 3',5'-cyclic phosphodiesterase0303
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Bifunctional cytochrome P450/NADPH--P450 reductase0011
UDP-glucuronosyltransferase 2B70203
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 10101
UDP-glucuronosyltransferase 1-60102
Potassium-transporting ATPase alpha chain 10101
UDP-glucuronosyltransferase 1A1 0101
UDP-glucuronosyltransferase 1A40102
Bombesin receptor subtype-30011
Cytochrome P450 2C190102
UDP-glucuronosyltransferase 2B10 0101
Fatty acid synthase0202
Sodium/potassium-transporting ATPase subunit alpha-20101
Potassium-transporting ATPase subunit beta0101
Potassium-transporting ATPase alpha chain 20001
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
WD repeat-containing protein 50101
Glutathione S-transferase omega-10101
Histone-lysine N-methyltransferase 2A0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Cytosolic endo-beta-N-acetylglucosaminidase0101
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0213
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
endonuclease IV2002
vasopressin V1b receptor1001
relaxin receptor 1 isoform 11001
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
Tumor necrosis factor0101
Cholinesterase0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0303
Adenosine receptor A2b0203
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0303
Chitotriosidase-10314
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0202
Endochitinase B10314
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Cytochrome P450 2B60202
Sodium-dependent serotonin transporter0101
Delta-type opioid receptor0102
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
Chain D, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, PROTEIN (PHOSPHOGLYCERATE MUTASE 1)0101
Chain A, Beta-arrestin 10011
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Acetylcholinesterase0101
Acetylcholinesterase 0101
Caspase-71001
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase 0101
Carbonic anhydrase0101
Carbonic anhydrase 120102
Carbonic anhydrase 30102
D(3) dopamine receptor0202
Carbonic anhydrase 60102
Alpha-1D adrenergic receptor0101
Mu-type opioid receptor0101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
Carbonic anhydrase0101
Taste receptor type 2 member 310011
Mu-type opioid receptor0101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Carbonic anhydrase 90102
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase0101
Carbonic anhydrase 0101
Delta carbonic anhydrase0101
RmtA0101
Protein arginine N-methyltransferase 10101
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Carbonic anhydrase 130001
Transcription regulator protein BACH10101
Transcription factor MafK 0101
Macrophage migration inhibitory factor0101
NAD0001
Quinone oxidoreductase0003
Kelch-like ECH-associated protein 10123
Nuclear factor erythroid 2-related factor 20124
Nuclear factor erythroid 2-related factor 20001
NAD(P)H dehydrogenase [quinone] 10001
Kelch-like ECH-associated protein 10001
Chain A, CES1 protein0101
DNA polymerase III, partial1001
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
streptokinase A precursor0022
Transmembrane protease serine 20011
Serine/threonine-protein kinase D30101
Estrogen receptor0214
Receptor tyrosine-protein kinase erbB-20101
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Progesterone receptor0101
Procathepsin L0011
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Protein kinase C alpha type0101
D(4) dopamine receptor0202
Protein kinase C eta type0101
Substance-P receptor0202
B2 bradykinin receptor0202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Protein kinase C iota type0101
Melanocortin receptor 30202
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 60202
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Nuclear receptor subfamily 3 group C member 3 0202
Estrogen receptor beta0213
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Beta-adrenergic receptor kinase 10011
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
Phosphodiesterase 0202
Renin0101
Alkaline phosphatase, tissue-nonspecific isozyme0202
5-hydroxytryptamine receptor 1A0101
Intestinal-type alkaline phosphatase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Adenosine receptor A30101
Adenosine receptor A2b0102
Vasopressin V2 receptor0001
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0202
Adenylate cyclase type 10001
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0101
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Sigma non-opioid intracellular receptor 10202
Adenosine receptor A2b0001
Palmitoleoyl-protein carboxylesterase NOTUM0011
Phospholipase A-2-activating protein0101
Proton-coupled amino acid transporter 10101
Protein Rev 0011
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit0101
Seminal ribonuclease0101
Ribonucleoside-diphosphate reductase large subunit0001
Ribonucleoside-diphosphate reductase subunit M20001
P2Y purinoceptor 20022
P2Y purinoceptor 10022
P2Y purinoceptor 40022
Ribonuclease pancreatic0101
UDP-galactopyranose mutase0011
P2Y purinoceptor 60022
P2Y purinoceptor 140011
UDP-galactopyranose mutase0011
P2Y purinoceptor 60011
Ribonucleoside-diphosphate reductase subunit M2 B0001
P2Y purinoceptor 40011
Thromboxane A2 receptor 0011
N-acetyllactosaminide alpha-1,3-galactosyltransferase0101
Sodium-dependent dopamine transporter0011
P2Y purinoceptor 2 0112
P2Y purinoceptor 20011
RNA-directed RNA polymerase 0001
P2Y purinoceptor 110011
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Aldo-keto reductase family 1 member A10101
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Receptor-type tyrosine-protein phosphatase F0101
Tyrosine-protein phosphatase non-receptor type 20101
Tyrosine-protein phosphatase non-receptor type 10101
Tyrosine-protein phosphatase non-receptor type 60101
Tyrosine-protein phosphatase non-receptor type 110101
twin arginine protein translocation system - TatA protein0001
30S ribosomal protein S60101
30S ribosomal protein S70101
50S ribosomal protein L150101
50S ribosomal protein L100101
50S ribosomal protein L110101
50S ribosomal protein L7/L120101
50S ribosomal protein L190101
50S ribosomal protein L10101
50S ribosomal protein L200101
50S ribosomal protein L270101
50S ribosomal protein L280101
50S ribosomal protein L290101
50S ribosomal protein L310101
50S ribosomal protein L31 type B0101
50S ribosomal protein L320101
50S ribosomal protein L330101
50S ribosomal protein L340101
50S ribosomal protein L350101
50S ribosomal protein L360101
30S ribosomal protein S100101
30S ribosomal protein S110101
30S ribosomal protein S120101
30S ribosomal protein S130101
30S ribosomal protein S160101
30S ribosomal protein S180101
30S ribosomal protein S190101
30S ribosomal protein S200101
30S ribosomal protein S20101
30S ribosomal protein S30101
30S ribosomal protein S40101
30S ribosomal protein S50101
30S ribosomal protein S80101
30S ribosomal protein S90101
50S ribosomal protein L130101
50S ribosomal protein L140101
50S ribosomal protein L160101
50S ribosomal protein L230101
30S ribosomal protein S150101
50S ribosomal protein L170101
50S ribosomal protein L210101
50S ribosomal protein L300101
50S ribosomal protein L60101
30S ribosomal protein S140101
30S ribosomal protein S170101
30S ribosomal protein S10101
50S ribosomal protein L180101
50S ribosomal protein L20101
50S ribosomal protein L30101
50S ribosomal protein L240101
50S ribosomal protein L40101
50S ribosomal protein L220101
50S ribosomal protein L50101
30S ribosomal protein S210101
50S ribosomal protein L250101
50S ribosomal protein L36 20101
Protein-arginine deiminase type-40101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]