Page last updated: 2024-09-28

Cheyne-Stokes Respiration

An abnormal pattern of breathing characterized by alternating periods of apnea and deep, rapid breathing. The cycle begins with slow, shallow breaths that gradually increase in depth and rate and is then followed by a period of apnea. The period of apnea can last 5 to 30 seconds, then the cycle repeats every 45 seconds to 3 minutes.

Synonyms(1)

Synonym
Cheyne-Stokes Respiration

Research

Studies (228)

TimeframeStudies, This Condition (%)All Conditions %
pre-199084 (36.84)23.3326
1990's43 (18.86)12.5806
2000's59 (25.88)18.1394
2010's39 (17.11)28.8240
2020's3 (1.32)9.53
DrugIndicatedRelationship StrengthStudiesTrials
carbon monoxide0low20
glycine0low10
hydrogen cyanide0low10
hydrogen carbonate0low10
melatonin0low10
nitrous oxide0low10
sulfur dioxide0low10
urea0low10
tacrine0low10
acetazolamide0medium112
theophylline0low170
bupivacaine0low10
caffeine0low10
diazepam0low10
ethylenediamine0low10
fentanyl0low10
gentamicin0low10
lidocaine0low10
meperidine0low20
mepivacaine0low10
methadone0low20
milrinone0low10
modafinil0low10
apnea0medium341
nitroglycerin0medium11
pentobarbital0low20
phenobarbital0low20
promethazine0low10
protriptyline0low10
temazepam0low10
penicillin g0low10
metaraminol0low10
pentylenetetrazole0low10
cyanides0low10
kanamycin a0low10
edetic acid0low10
trichloroacetic acid0low10
aminophylline0low100
n-pentyl nitrite0low10
medroxyprogesterone0low10
oxophenarsine0low10
mercury0low10
chlorine0low10
paraldehyde0low10
carbamide peroxide0low10
4-methoxyamphetamine0low10
amoxicillin0low10
timolol0low10
fomesafen0medium51
detomidine0low10
clopidogrel0low10
3-iodobenzylguanidine0medium11
adenosine0low20
cobalt0low10
atropine0low10
digitoxin0low20
tretinoin0low10
cocaine0low10
lithium0low10
codeine0low10
phenylephrine hydrochloride0medium52
dihydrocodeine0low10
naloxone0low10
iloprost0medium11
arsenic0low10
butorphanol0low10
triolein0low10
ticagrelor0low40
endothelin-10low10
sodium oxybate0low30
cardiovascular agents0medium11
natriuretic peptide, brain0medium163
nitrophenols0low10
eye0low20

Protein Targets (865)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
dopamine D1 receptor2002
thioredoxin reductase160016
GLS protein9009
Thrombopoietin2002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)6006
cytochrome P450 2D6 isoform 15005
cytochrome P450 2C19 precursor3003
ras-related protein Rab-9A3003
histone acetyltransferase KAT2A isoform 13003
lethal factor (plasmid)5005
POU domain, class 2, transcription factor 10001
Spike glycoprotein81110
ATP-dependent phosphofructokinase110011
5-hydroxytryptamine receptor 2C0415
5-hydroxytryptamine receptor 2A0516
5-hydroxytryptamine receptor 1A09312
5-hydroxytryptamine receptor 1B0617
5-hydroxytryptamine receptor 1D0213
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 2B0415
5-hydroxytryptamine receptor 60112
Sodium-dependent serotonin transporter0718
Sodium-dependent serotonin transporter0809
5-hydroxytryptamine receptor 7 0112
5-hydroxytryptamine receptor 5A0112
5-hydroxytryptamine receptor 5B0112
5-hydroxytryptamine receptor 3A0112
5-hydroxytryptamine receptor 4 0112
5-hydroxytryptamine receptor 3B0112
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, CARBONIC ANHYDRASE II0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Carbonic Anhydrase Ii0011
Chain A, Beta-lactamase7007
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Endochitinase0101
Chain A, Class Iii Chitinase Chia10101
Chain A, Carbonic anhydrase 130101
Chain A, Carbonic anhydrase II0101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase 20101
Chain A, Carbonic anhydrase0101
Chain B, Carbonic anhydrase0101
Chain A, Carbonic anhydrase 20101
Carbonic anhydrase 0001
Carbonic anhydrase 0101
GALC protein3003
GLI family zinc finger 3190019
nuclear receptor subfamily 1, group I, member 3140014
cytochrome P450 family 3 subfamily A polypeptide 4100010
glucocorticoid receptor [Homo sapiens]150015
retinoic acid nuclear receptor alpha variant 1140014
retinoid X nuclear receptor alpha110011
estrogen-related nuclear receptor alpha170017
Carbonic anhydrase 0101
Carbonic anhydrase 0202
arylsulfatase A8008
Carbonic anhydrase0202
euchromatic histone-lysine N-methyltransferase 2150015
Bloom syndrome protein isoform 18008
thyroid hormone receptor beta isoform a4004
nuclear factor erythroid 2-related factor 2 isoform 1160016
geminin130013
peripheral myelin protein 22110011
survival motor neuron protein isoform d3003
muscleblind-like protein 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi73212
ATP-binding cassette sub-family C member 3019019
Multidrug resistance-associated protein 4019019
Carbonic anhydrase0101
Solute carrier family 22 member 60202
Carbonic anhydrase 120216
Prolyl endopeptidase0101
Carbonic anhydrase-related protein 110102
Bile salt export pump024024
Glycogen phosphorylase, muscle form0202
Renin0404
Carbonic anhydrase 106112
Carbonic anhydrase 206111
Carbonic anhydrase 20202
Cytochrome P450 1A20415
Carbonic anhydrase 30216
Cathepsin B0101
Cytochrome P450 3A40213
Steryl-sulfatase0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Cytochrome P450 2C80202
Cytochrome P450 2D60617
Cytochrome P450 2A60101
Cytochrome P450 2C9 0314
Androgen receptor0303
Gamma-aminobutyric acid receptor subunit beta-173212
Translocator protein0214
Gamma-aminobutyric acid receptor subunit delta73212
Gamma-aminobutyric acid receptor subunit gamma-273212
Gamma-aminobutyric acid receptor subunit alpha-573212
Gamma-aminobutyric acid receptor subunit alpha-373212
Cannabinoid receptor 10101
Arachidonate 5-lipoxygenase-activating protein0101
Cytochrome P450 2B60303
Carbonic anhydrase 40518
Carbonic anhydrase 60316
Gamma-aminobutyric acid receptor subunit gamma-173212
Gamma-aminobutyric acid receptor subunit alpha-273212
Carbonic anhydrase 5A, mitochondrial0101
Adenosine receptor A106110
Serum paraoxonase/arylesterase 10101
Dipeptidyl peptidase 40001
Gamma-aminobutyric acid receptor subunit alpha-473212
Gamma-aminobutyric acid receptor subunit gamma-373212
Endochitinase0101
Gamma-aminobutyric acid receptor subunit alpha-673212
Adenosine receptor A2a05111
Delta-type opioid receptor0719
Cytochrome P450 2C190516
Delta-type opioid receptor0527
Mu-type opioid receptor0639
Carbonic anhydrase 5A, mitochondrial0317
Carbonic anhydrase0405
Kappa-type opioid receptor0518
Carbonic anhydrase 70316
Carbonic anhydrase0101
D(1A) dopamine receptor1102
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase0102
D(2) dopamine receptor0202
Gamma-aminobutyric acid receptor subunit alpha-173212
Gamma-aminobutyric acid receptor subunit beta-373212
Gamma-aminobutyric acid receptor subunit beta-273212
Cholinesterase0303
Carbonic anhydrase 0101
Mu-type opioid receptor0617
Fatty-acid amide hydrolase 10101
Beta-carbonic anhydrase 10101
Carbonic anhydrase 20101
Glutamate receptor ionotropic, NMDA 2B0416
Squalene synthase0202
Neuronal acetylcholine receptor subunit alpha-70202
Carbonic anhydrase 90317
Carbonic anhydrase0101
Carbonic anhydrase, alpha family 0101
Carbonic anhydrase 0102
Carbonic anhydrase 30101
Carbonic anhydrase0204
Carbonic anhydrase0103
Carbonic anhydrase 0101
Sigma intracellular receptor 20101
Delta carbonic anhydrase0101
Sigma non-opioid intracellular receptor 10606
Renin0101
Carbonic anhydrase 0102
Endochitinase A10101
Multidrug resistance-associated protein 10101
Carbonic anhydrase 130214
GABA theta subunit73212
Canalicular multispecific organic anion transporter 1018018
Carbonic anhydrase 40202
Carbonic anhydrase 150305
Acidic mammalian chitinase0101
Carbonic anhydrase 130305
Carbonic anhydrase 70101
Gamma-aminobutyric acid receptor subunit epsilon73212
Carbonic anhydrase 0101
Carbonic anhydrase 140216
Carbonic anhydrase 0101
Carbonic anhydrase 2, isoform A 0101
Carbonic anhydrase 5B, mitochondrial0317
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Membrane lipoprotein tmpC0011
Chain A, Structure of PAE2307 in complex with adenosine0011
Chain B, Structure of PAE2307 in complex with adenosine0011
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, ADENOSINE RECEPTOR A2A0101
Chain A, tRNA (guanine-N(1)-)-methyltransferase0011
Chain A, Uncharacterized protein MJ08830011
AR protein250025
signal transducer and activator of transcription 6, interleukin-4 induced1001
regulator of G-protein signaling 48008
estrogen nuclear receptor alpha240024
NPYLR7B0011
IDH15005
Histone H2A.x4004
glycogen synthase kinase-3 beta isoform 10011
mitogen-activated protein kinase 13003
flap endonuclease 13003
nuclear receptor ROR-gamma isoform 15005
high affinity choline transporter 1 isoform a0101
Sodium/nucleoside cotransporter 10202
Calcium dependent protein kinase0101
Mitogen-activated protein kinase kinase kinase 70011
Sodium/nucleoside cotransporter 20202
Voltage-dependent calcium channel gamma-2 subunit8008
Rap guanine nucleotide exchange factor 32002
Purine nucleoside phosphorylase0101
Epidermal growth factor receptor0202
Phosphoglycerate kinase 1 0101
Adenosine deaminase0001
Avidin0011
Adenosine deaminase0001
Glyceraldehyde-3-phosphate dehydrogenase0202
Receptor tyrosine-protein kinase erbB-20101
Insulin receptor0001
Phosphoglycerate kinase 20101
Heat shock protein HSP 90-alpha0112
Platelet-derived growth factor receptor beta0001
Adenosine receptor A30629
Heat shock 70 kDa protein 1A 0101
Heat shock cognate 71 kDa protein0011
Fibroblast growth factor receptor 10001
Inosine-5'-monophosphate dehydrogenase 20101
Endoplasmin0112
Glutamate receptor 28008
Inosine-5'-monophosphate dehydrogenase 1 0101
Fibroblast growth factor receptor 20001
Fibroblast growth factor receptor 40001
Fibroblast growth factor receptor 30001
Streptavidin0011
Adenosylhomocysteinase0001
Adenosine receptor A30303
Adenosine receptor A2a05513
Adenosine receptor A2b0216
Adenosine receptor A2b0417
Adenylate kinase 2, mitochondrial0101
Adenosine receptor A106415
Adenylate kinase isoenzyme 1 0101
Phosphatidylinositol 4-kinase alpha0203
Adenosine receptor A10213
Adenosine kinase0001
Adenosine deaminase 0001
Equilibrative nucleoside transporter 20202
Phosphatidylinositol 4-kinase type 2-beta0203
Histone-lysine N-methyltransferase, H3 lysine-79 specific0101
Equilibrative nucleoside transporter 10202
Phosphatidylinositol 4-kinase type 2-alpha0203
Solute carrier family 28 member 30202
Adenosine kinase0102
Phosphatidylinositol 4-kinase beta0203
5-methylthioadenosine/S-adenosylhomocysteine deaminase0001
Adenosine transporter 10001
USP1 protein, partial3003
Microtubule-associated protein tau7007
lamin isoform A-delta10150015
Chain A, 2-oxoglutarate Oxygenase100010
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
apical membrane antigen 1, AMA12002
Beta-lactamase 0002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 14004
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)3003
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
DNA polymerase kappa isoform 15005
Bile salt export pump0202
Beta-lactamase SHV-10002
Beta-lactamase SHV-10002
Beta-lactamase0002
Solute carrier family 15 member 10303
Solute carrier family 15 member 10101
Cytochrome P450 2J20202
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20202
Beta-lactamase 0002
Beta-lactamase 0002
Solute carrier family 15 member 20202
Beta-lactamase 0002
Beta-lactamase 0002
ATAD5 protein, partial5005
TDP1 protein140014
D(1A) dopamine receptor3003
neuropeptide S receptor isoform A1001
pregnane X nuclear receptor170017
cystic fibrosis transmembrane conductance regulator0101
DNA polymerase beta2002
short transient receptor potential channel 6 isoform 10011
Solute carrier family 22 member 1 0606
5-hydroxytryptamine receptor 40404
Muscarinic acetylcholine receptor M20519
Muscarinic acetylcholine receptor M40417
Muscarinic acetylcholine receptor M10518
Muscarinic acetylcholine receptor M30417
Muscarinic acetylcholine receptor M40417
Muscarinic acetylcholine receptor M50417
Muscarinic acetylcholine receptor M50417
Muscarinic acetylcholine receptor M20418
Muscarinic acetylcholine receptor M10519
Muscarinic acetylcholine receptor M10001
Muscarinic acetylcholine receptor M30417
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2C0404
Muscarinic acetylcholine receptor M40101
Histamine H2 receptor3004
5-hydroxytryptamine receptor 70202
Reverse transcriptase/RNaseH 0001
Muscarinic acetylcholine receptor0113
Potassium channel subfamily K member 30303
Potassium channel subfamily K member 30101
Potassium channel subfamily K member 20134
Potassium channel subfamily K member 90101
Mu-type opioid receptor011416
Delta-type opioid receptor09111
Kappa-type opioid receptor09313
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
phosphopantetheinyl transferase6006
RAR-related orphan receptor gamma140014
farnesoid X nuclear receptor4004
thyroid stimulating hormone receptor5005
v-jun sarcoma virus 17 oncogene homolog (avian)5005
atrial natriuretic peptide receptor 1 precursor2002
chromobox protein homolog 1130013
thyroid hormone receptor beta isoform 2110011
muscarinic acetylcholine receptor M18008
Cholinesterase0404
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0314
Replicase polyprotein 1ab0415
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0404
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0505
Vasopressin V2 receptor0002
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0202
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0202
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10002
Chitotriosidase-10202
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0103
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0235
Endochitinase B10202
Phosphodiesterase 0101
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Guanine deaminase0101
EWS/FLI fusion protein5005
nonstructural protein 12002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Liver carboxylesterase 10205
Rap guanine nucleotide exchange factor 41001
P2Y purinoceptor 120303
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0404
Gamma-aminobutyric acid receptor subunit delta0404
Amyloid-beta precursor protein0404
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20112
Tryptophan 5-hydroxylase 10101
Gamma-aminobutyric acid receptor subunit alpha-10527
Gamma-aminobutyric acid receptor subunit beta-10404
Gamma-aminobutyric acid receptor subunit gamma-20426
D0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Sodium-dependent noradrenaline transporter 09110
Sodium-dependent dopamine transporter0606
Gamma-aminobutyric acid receptor subunit beta-30516
Gamma-aminobutyric acid receptor subunit alpha-50426
Gamma-aminobutyric acid receptor subunit alpha-30415
Glutamate receptor ionotropic, NMDA 1 0315
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20426
Gamma-aminobutyric acid receptor subunit beta-20426
Gamma-aminobutyric acid receptor subunit alpha-40404
Gamma-aminobutyric acid receptor subunit epsilon0404
Glutamate receptor ionotropic, NMDA 2A 0315
Glutamate receptor ionotropic, NMDA 2C0315
Sodium-dependent dopamine transporter 0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0404
Potassium voltage-gated channel subfamily H member 2010010
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60404
Sodium-dependent dopamine transporter0202
Glutamate receptor ionotropic, NMDA 2D0315
Gamma-aminobutyric acid receptor subunit gamma-10404
Glutamate receptor ionotropic, NMDA 3B0315
Sigma non-opioid intracellular receptor 10707
Gamma-aminobutyric acid receptor subunit gamma-30404
Leukotriene B4 receptor 20112
Glutamate receptor ionotropic, NMDA 3A0315
Gamma-aminobutyric acid receptor subunit theta0404
Transporter0505
Cytochrome P450 2D10101
Cytochrome P450 2D260101
Cytochrome P450 2D30101
UDP-glucuronosyltransferase 2B70001
Kappa-type opioid receptor0304
Mu-type opioid receptor0405
Cytochrome P450 2D40101
Mas-related G-protein coupled receptor member X20022
Gamma-aminobutyric acid 0101
glp-1 receptor, partial4004
estrogen receptor 2 (ER beta)4004
progesterone receptor8008
G5005
peroxisome proliferator activated receptor gamma7007
vitamin D (1,25- dihydroxyvitamin D3) receptor9009
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
Voltage-dependent L-type calcium channel subunit alpha-1F0404
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 5005
Fatty acid-binding protein, liver0101
Alpha-1-acid glycoprotein 10001
Albumin0012
Albumin0011
Cellular tumor antigen p53100010
ATP-dependent translocase ABCB10203
Gamma-aminobutyric acid receptor subunit alpha-10202
Gamma-aminobutyric acid receptor subunit beta-10202
Neuronal acetylcholine receptor subunit alpha-41203
Gamma-aminobutyric acid receptor subunit alpha-20202
Gamma-aminobutyric acid receptor subunit alpha-30202
Neuronal acetylcholine receptor subunit beta-21203
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit gamma-20202
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Translocator protein0101
Translocator protein0202
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Voltage-dependent L-type calcium channel subunit alpha-1D 0404
Voltage-dependent L-type calcium channel subunit alpha-1S0404
Voltage-dependent L-type calcium channel subunit alpha-1C0404
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
Inositol hexakisphosphate kinase 15005
ATPase family AAA domain-containing protein 55005
Ataxin-28008
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
cytochrome P450 2C9, partial5005
Chain A, Cruzipain2002
acetylcholinesterase4004
SMAD family member 24004
SMAD family member 34004
STAT3, partial0101
Smad31001
67.9K protein1001
peroxisome proliferator-activated receptor delta4004
activating transcription factor 65005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
nuclear receptor subfamily 1, group I, member 21001
NPC intracellular cholesterol transporter 1 precursor1001
nuclear factor erythroid 2-related factor 2 isoform 22002
potassium voltage-gated channel subfamily H member 2 isoform d4004
signal transducer and activator of transcription 1-alpha/beta isoform alpha0101
Sodium/potassium-transporting ATPase subunit alpha-1 0101
Sodium/potassium-transporting ATPase subunit beta-10101
Sodium/potassium-transporting ATPase subunit alpha-30101
Sodium/potassium-transporting ATPase subunit beta-20101
Sodium/potassium-transporting ATPase subunit alpha-20101
Sodium/potassium-transporting ATPase subunit alpha-10101
Sodium/potassium-transporting ATPase subunit beta-30101
Sodium/potassium-transporting ATPase subunit gamma0101
Sodium/potassium-transporting ATPase subunit alpha-40101
Solute carrier organic anion transporter family member 4C10101
hypoxia-inducible factor 1 alpha subunit4004
Eyes absent homolog 20101
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130102
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0102
Endothelin-1 receptor0101
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha0101
Protein farnesyltransferase subunit beta0101
Glutaminyl-peptide cyclotransferase0101
Luciferase6006
Nuclear receptor subfamily 1 group I member 20011
D(2) dopamine receptor0505
D(4) dopamine receptor0303
Kappa-type opioid receptor0224
Histamine H1 receptor0303
D(3) dopamine receptor0505
Sigma non-opioid intracellular receptor 10202
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10202
Proton-coupled amino acid transporter 10101
Serine racemase0101
Olfactory receptor 51E20022
Sodium- and chloride-dependent glycine transporter 20101
Prostaglandin E2 receptor EP1 subtype0011
Prostaglandin E2 receptor EP3 subtype0101
Prostaglandin E2 receptor EP2 subtype0011
Prostacyclin receptor0213
Prostacyclin receptor0112
Solute carrier organic anion transporter family member 2A10001
Prostaglandin D2 receptor0011
3-oxoacyl-[acyl-carrier-protein] synthase 30101
Gap junction alpha-1 protein0101
Gap junction beta-2 protein0101
Acyl-protein thioesterase 10101
Chain A, HADH2 protein4004
Chain B, HADH2 protein4004
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
15-lipoxygenase, partial2002
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
importin subunit beta-1 isoform 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
snurportin-11001
M-phase phosphoprotein 84004
Polyphenol oxidase 20001
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Tyrosinase0101
SLC16A10 protein0001
Carbonic anhydrase-like protein, putative0001
Monocarboxylate transporter 100001
phosphoglycerate kinase1001
aldehyde dehydrogenase 1 family, member A19009
cytochrome P450 3A4 isoform 17007
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Potassium voltage-gated channel subfamily A member 50101
Sodium channel protein type 4 subunit alpha0101
Sodium channel protein type 5 subunit alpha0101
Sodium channel protein type 9 subunit alpha0101
Potassium voltage-gated channel subfamily D member 20101
Potassium channel subfamily K member 180101
Multidrug and toxin extrusion protein 10202
Sodium channel protein type 3 subunit alpha0202
PINK11001
Parkin2002
Glucocorticoid receptor0202
Glycine receptor subunit alpha-10202
Glycine receptor subunit beta0202
Glycine receptor subunit alpha-20202
Glycine receptor subunit alpha-30202
interleukin 81001
ClpP1001
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
aryl hydrocarbon receptor5005
peripheral myelin protein 22 isoform 11001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Myeloperoxidase0101
Cytochrome P450 2C11 0101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0303
Nociceptin receptor0101
Alpha-1A adrenergic receptor0303
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Nuclear receptor ROR-gamma2114
Nuclear factor erythroid 2-related factor 20001
Cytochrome P450 1B10101
Carboxylic ester hydrolase 0303
Histamine H3 receptor0101
cytochrome P450 2D67007
Macrophage migration inhibitory factor0202
Aldehyde oxidase 1 0101
thyroid stimulating hormone receptor3003
Phosphodiesterase 0303
Vpr2002
cGMP-dependent 3',5'-cyclic phosphodiesterase0202
Aurora kinase A0101
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A0101
cGMP-specific 3',5'-cyclic phosphodiesterase0101
3',5'-cyclic-AMP phosphodiesterase 0101
Prostaglandin G/H synthase 10101
Dual specificity protein kinase TTK0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0303
cGMP-inhibited 3',5'-cyclic phosphodiesterase B0303
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0202
cGMP-inhibited 3',5'-cyclic phosphodiesterase A0303
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Aurora kinase B0101
Inner centromere protein0101
Phosphodiesterase 0101
thioredoxin glutathione reductase2002
Transporter0101
Histidine decarboxylase0011
D(3) dopamine receptor0202
Beta-2 adrenergic receptor0112
UDP-glucuronosyltransferase 1A80001
Atrial natriuretic peptide receptor 10101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
streptokinase A precursor0011
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase TEM0102
Guanine nucleotide-binding protein G2002
Beta-lactamase0001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Solute carrier family 22 member 80101
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Alpha-synuclein1102
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10022
5-hydroxytryptamine receptor 2A0022
glucocerebrosidase1001
Snq2p0001
Spike glycoprotein0112
Replicase polyprotein 1ab0112
vitamin D3 receptor isoform VDRA2002
huntingtin isoform 21001
serine/threonine-protein kinase mTOR isoform 11001
Transmembrane protease serine 20112
Major prion protein0011
Procathepsin L0112
Aldo-keto reductase family 1 member B10404
Alpha-2A adrenergic receptor0202
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Calmodulin-10101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
D(1A) dopamine receptor0202
Histamine H2 receptor0202
5-hydroxytryptamine receptor 2A0202
Trypanothione reductase0303
Pleiotropic ABC efflux transporter of multiple drugs0102
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60202
Calmodulin 0011
Inositol monophosphatase 12002
Voltage-dependent N-type calcium channel subunit alpha-1B0303
Angiotensin-converting enzyme 2 0112
Chloroquine resistance transporter0101
NFKB1 protein, partial3003
cellular tumor antigen p53 isoform a2002
atrial natriuretic peptide receptor 2 precursor1001
chaperonin GroEL1001
Sulfotransferase 1A10101
Sulfotransferase 2A10101
Free fatty acid receptor 30011
Chain A, ACETYLCHOLINESTERASE0101
Chain A, liver Carboxylesterase I0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Chain A, Histamine N-methyltransferase0101
Glycogen synthase kinase-3 beta 0101
[Tau protein] kinase 0101
Voltage-dependent L-type calcium channel subunit beta-40101
Voltage-dependent P/Q-type calcium channel subunit alpha-1A0101
Solute carrier family 22 member 20101
Acetylcholinesterase0213
Voltage-dependent T-type calcium channel subunit alpha-1G0101
Voltage-dependent calcium channel gamma-3 subunit0101
Voltage-dependent T-type calcium channel subunit alpha-1H0101
Coagulation factor XII0101
Acetylcholinesterase0202
Neuronal acetylcholine receptor subunit alpha-30101
Cytochrome P450 2E10101
Fatty acid-binding protein, liver0011
Acyl-CoA desaturase 10101
Neuronal acetylcholine receptor subunit beta-40101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A 0101
Amine oxidase [flavin-containing] A 0101
Cannabinoid receptor 10101
Acetylcholinesterase0213
Choline O-acetyltransferase 0101
Cannabinoid receptor 2 0101
Acetylcholinesterase0202
Neuronal acetylcholine receptor subunit alpha-60101
Glycogen synthase kinase-3 beta0101
Histamine N-methyltransferase0001
Gastrotropin0011
Voltage-dependent L-type calcium channel subunit beta-30101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent calcium channel gamma-7 subunit0101
Small conductance calcium-activated potassium channel protein 30101
Cyclin-dependent-like kinase 5 0101
Histamine N-methyltransferase 0101
Voltage-dependent L-type calcium channel subunit beta-10101
Cholinesterase0101
Acetylcholine receptor subunit epsilon0202
Glutamate receptor ionotropic, NMDA 10101
Voltage-dependent calcium channel gamma-1 subunit0101
Voltage-dependent L-type calcium channel subunit beta-20101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Cyclin-dependent kinase 5 activator 10101
Voltage-dependent R-type calcium channel subunit alpha-1E0101
Voltage-dependent calcium channel subunit alpha-2/delta-40101
Multidrug and toxin extrusion protein 20101
Voltage-dependent calcium channel subunit alpha-2/delta-30101
Voltage-dependent calcium channel gamma-8 subunit0101
Acyl-CoA:cholesterol acyltransferase 0101
Voltage-dependent calcium channel gamma-6 subunit0101
Carboxylic ester hydrolase 0102
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Voltage-dependent T-type calcium channel subunit alpha-1I0101
Voltage-dependent calcium channel gamma-4 subunit0101
Voltage-dependent calcium channel gamma-5 subunit0101
Voltage-dependent calcium channel gamma-2 subunit0101
Chain A, Pyridoxal kinase0101
Chain A, Pyridoxal Kinase0101
bromodomain adjacent to zinc finger domain 2B2002
transcriptional regulator ERG isoform 31001
Alkaline phosphatase, tissue-nonspecific isozyme0202
5-hydroxytryptamine receptor 1A0101
Intestinal-type alkaline phosphatase0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
Thyroid hormone receptor beta0101
Adenosine receptor A10202
Adenosine receptor A10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
TAR DNA-binding protein 431001
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A0101
Phospholipase A-2-activating protein0101
P2Y purinoceptor 130101
Beta-1 adrenergic receptor 0011
Beta-2 adrenergic receptor0202
Beta-1 adrenergic receptor0202
Beta-3 adrenergic receptor0202
Beta-1 adrenergic receptor0101
Chain A, Nuclear Receptor ROR-beta0101
Chain A, Ferritin light chain1001
pregnane X receptor1001
thyrotropin-releasing hormone receptor1001
Caspase-71001
caspase-31001
heat shock protein beta-11001
Ornithine decarboxylase0001
Ornithine decarboxylase0001
60 kDa chaperonin0101
Retinoic acid receptor alpha0227
60 kDa heat shock protein, mitochondrial0101
Retinoic acid receptor beta0227
Retinoic acid receptor alpha0123
Retinoic acid receptor gamma 0227
Alpha-1B adrenergic receptor0202
Alpha-1A adrenergic receptor0101
Retinoic acid receptor gamma0123
Retinoic acid receptor RXR-alpha0224
Retinoic acid receptor beta0123
Cellular retinoic acid-binding protein 20011
Alpha-1D adrenergic receptor0101
Mitogen-activated protein kinase 10101
Retinoic acid receptor RXR-alpha0123
Retinoic acid receptor RXR-beta0224
Retinoic acid receptor RXR-beta0123
Retinoic acid receptor RXR-gamma0123
Indoleamine 2,3-dioxygenase 10101
Nuclear receptor ROR-alpha0101
Cellular retinoic acid-binding protein 10102
Retinoic acid receptor RXR-gamma0224
10 kDa heat shock protein, mitochondrial0101
Cellular retinoic acid-binding protein 10011
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10213
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Indoleamine 2,3-dioxygenase 20101
Nuclear receptor ROR-beta0101
Integrin beta-31001
Integrin alpha-IIb1001
Urease subunit alpha0101
Urease subunit beta0101
Thromboxane A2 receptor 0001
Type-1A angiotensin II receptor 0112
Type-1B angiotensin II receptor0101
Type-1 angiotensin II receptor0214
Type-1 angiotensin II receptor0101
Type-2 angiotensin II receptor0101
Platelet glycoprotein VI0011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]