| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 2 | 0 | 0 | 2 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 3E | 0 | 1 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| SMAD family member 2 | 2 | 0 | 0 | 2 |
| Fumarate hydratase | 2 | 0 | 0 | 2 |
| USP1 protein, partial | 2 | 0 | 0 | 2 |
| PPM1D protein | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 2 | 0 | 0 | 2 |
| TDP1 protein | 3 | 0 | 0 | 3 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| AR protein | 4 | 0 | 0 | 4 |
| estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 3 | 0 | 0 | 3 |
| progesterone receptor | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 2 | 0 | 0 | 2 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 4 | 0 | 0 | 4 |
| estrogen-related nuclear receptor alpha | 3 | 0 | 0 | 3 |
| farnesoid X nuclear receptor | 2 | 0 | 0 | 2 |
| pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
| estrogen nuclear receptor alpha | 4 | 0 | 0 | 4 |
| G | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| polyprotein | 2 | 0 | 0 | 2 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 4 | 0 | 0 | 4 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 2 | 0 | 0 | 2 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| mu-type opioid receptor isoform MOR-1 | 0 | 0 | 1 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 5 | 0 | 0 | 5 |
| nuclear receptor ROR-gamma isoform 1 | 2 | 0 | 0 | 2 |
| geminin | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 | 3 | 0 | 0 | 3 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 0 | 1 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Solute carrier family 22 member 2 | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 4 | 0 | 4 |
| Interferon beta | 3 | 0 | 0 | 3 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
| ATP-dependent translocase ABCB1 | 0 | 3 | 0 | 3 |
| Cytochrome P450 3A4 | 0 | 5 | 0 | 5 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 1 | 3 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| D(2) dopamine receptor | 0 | 3 | 1 | 4 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 3 | 0 | 3 |
| D | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Glutamate receptor 2 | 2 | 0 | 0 | 2 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| D(1A) dopamine receptor | 0 | 1 | 0 | 1 |
| D(4) dopamine receptor | 0 | 1 | 0 | 1 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 8 | 1 | 10 |
| 5-hydroxytryptamine receptor 2C | 0 | 7 | 0 | 7 |
| D(4) dopamine receptor | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 4 | 1 | 5 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Histamine H1 receptor | 0 | 3 | 0 | 3 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 1 | 1 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 5 | 0 | 5 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 1 | 0 | 1 |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 2 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 7 | 0 | 7 |
| 5-hydroxytryptamine receptor 3D | 0 | 1 | 0 | 1 |
| Multidrug and toxin extrusion protein 2 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3C | 0 | 1 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| Multidrug and toxin extrusion protein 1 | 0 | 1 | 0 | 1 |
| Histamine H3 receptor | 0 | 2 | 0 | 2 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Acetylcholinesterase | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| cGMP-specific 3',5'-cyclic phosphodiesterase | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 2 | 0 | 2 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 2 | 2 | 4 |
| Liver carboxylesterase 1 | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 2 | 0 | 2 |
| Amine oxidase [flavin-containing] B | 0 | 1 | 0 | 1 |
| Choline O-acetyltransferase | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Glycogen synthase kinase-3 beta | 0 | 1 | 0 | 1 |
| Beta-secretase 1 | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Acetylcholine receptor subunit epsilon | 0 | 1 | 0 | 1 |
| cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Cytochrome P450 1B1 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Acyl-CoA:cholesterol acyltransferase | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 3 | 0 | 3 |
| Carboxylic ester hydrolase | 0 | 1 | 0 | 1 |
| Carboxylic ester hydrolase | 0 | 2 | 0 | 2 |
| Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | 0 | 0 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 2 | 0 | 0 | 2 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| lamin isoform A-delta10 | 2 | 0 | 0 | 2 |
| chaperonin-containing TCP-1 beta subunit homolog | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| Synaptic vesicle glycoprotein 2A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3A | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily KQT member 1 | 0 | 1 | 0 | 1 |
| Cysteinyl leukotriene receptor 1 | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 3B | 0 | 1 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2D6 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 2 | 0 | 2 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| aryl hydrocarbon receptor | 1 | 0 | 0 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| heat shock protein 90, putative | 0 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Rap guanine nucleotide exchange factor 3 | 2 | 0 | 0 | 2 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Transcriptional activator protein LuxR | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 1 | 3 |
| Sodium-dependent dopamine transporter | 0 | 1 | 0 | 1 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
| Melanocortin receptor 5 | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 1 | 3 |
| Envelope glycoprotein | 0 | 0 | 1 | 1 |
| Sigma intracellular receptor 2 | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | 0 | 2 | 0 | 2 |
| Sigma non-opioid intracellular receptor 1 | 0 | 1 | 0 | 1 |
| Transporter | 0 | 1 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Urease subunit alpha | 0 | 1 | 0 | 1 |
| Urease subunit beta | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |