| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 3 | 0 | 0 | 3 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 6 | 0 | 0 | 6 |
| Chain A, Ferritin light chain | 4 | 0 | 0 | 4 |
| interleukin 8 | 2 | 0 | 0 | 2 |
| acetylcholinesterase | 4 | 0 | 0 | 4 |
| thioredoxin reductase | 2 | 0 | 0 | 2 |
| phosphopantetheinyl transferase | 3 | 0 | 0 | 3 |
| RAR-related orphan receptor gamma | 3 | 0 | 0 | 3 |
| SMAD family member 2 | 5 | 0 | 0 | 5 |
| ATAD5 protein, partial | 4 | 0 | 0 | 4 |
| Fumarate hydratase | 2 | 0 | 0 | 2 |
| SMAD family member 3 | 5 | 0 | 0 | 5 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| GLI family zinc finger 3 | 5 | 0 | 0 | 5 |
| Microtubule-associated protein tau | 3 | 0 | 0 | 3 |
| AR protein | 6 | 0 | 0 | 6 |
| thioredoxin glutathione reductase | 4 | 0 | 0 | 4 |
| nuclear receptor subfamily 1, group I, member 3 | 3 | 0 | 0 | 3 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 2 |
| glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 6 | 0 | 0 | 6 |
| retinoid X nuclear receptor alpha | 6 | 0 | 0 | 6 |
| estrogen-related nuclear receptor alpha | 7 | 0 | 0 | 7 |
| farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
| pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 6 | 0 | 0 | 6 |
| G | 2 | 0 | 0 | 2 |
| polyprotein | 2 | 0 | 0 | 2 |
| P53 | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| IDH1 | 3 | 0 | 0 | 3 |
| euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
| aryl hydrocarbon receptor | 6 | 0 | 0 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 5 | 0 | 0 | 5 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| activating transcription factor 6 | 4 | 0 | 0 | 4 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 5 | 0 | 0 | 5 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| hemoglobin subunit beta | 2 | 0 | 0 | 2 |
| cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 5 | 0 | 0 | 5 |
| heat shock protein beta-1 | 4 | 0 | 0 | 4 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 4 | 0 | 0 | 4 |
| DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
| geminin | 3 | 0 | 0 | 3 |
| peripheral myelin protein 22 | 2 | 0 | 0 | 2 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 2 | 0 | 2 |
| Multidrug resistance-associated protein 4 | 0 | 2 | 0 | 2 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Bile salt export pump | 0 | 3 | 0 | 3 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 6 | 0 | 0 | 6 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 2 | 0 | 2 |
| ATPase family AAA domain-containing protein 5 | 3 | 0 | 0 | 3 |
| Ataxin-2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| Protein-arginine deiminase type-4 | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Chain A, Breast cancer type 1 susceptibility protein | 1 | 0 | 0 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 2 | 0 | 0 | 2 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| Luciferase | 2 | 0 | 0 | 2 |
| Nrf2 | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| pregnane X receptor | 2 | 0 | 0 | 2 |
| hypoxia-inducible factor 1 alpha subunit | 3 | 0 | 0 | 3 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| GLS protein | 2 | 0 | 0 | 2 |
| alkaline phosphatase, intestinal | 0 | 1 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 3 | 0 | 0 | 3 |
| PINK1 | 1 | 0 | 0 | 1 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
| progesterone receptor | 5 | 0 | 0 | 5 |
| glucocerebrosidase | 1 | 0 | 0 | 1 |
| Parkin | 1 | 0 | 0 | 1 |
| bromodomain adjacent to zinc finger domain 2B | 2 | 0 | 0 | 2 |
| toll-like receptor 9 | 0 | 1 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 5 | 0 | 0 | 5 |
| caspase-3 | 1 | 0 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| TPA: protein transporter TIM10 | 0 | 1 | 0 | 1 |
| thyrotropin-releasing hormone receptor | 3 | 0 | 0 | 3 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 3 | 0 | 0 | 3 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein | 0 | 1 | 0 | 1 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 2 | 0 | 0 | 2 |
| perilipin-5 | 0 | 1 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 3 | 0 | 0 | 3 |
| intestinal alkaline phosphatase precursor | 0 | 1 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
| perilipin-1 | 0 | 1 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| huntingtin isoform 2 | 1 | 0 | 0 | 1 |
| importin subunit beta-1 isoform 1 | 1 | 0 | 0 | 1 |
| pyruvate kinase PKM isoform a | 1 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| nuclear factor NF-kappa-B p105 subunit isoform 1 | 1 | 0 | 0 | 1 |
| flap endonuclease 1 | 1 | 0 | 0 | 1 |
| snurportin-1 | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 1 | 0 | 0 | 1 |
| tumor susceptibility gene 101 protein | 1 | 0 | 0 | 1 |
| GTP-binding nuclear protein Ran isoform 1 | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| nuclear receptor ROR-gamma isoform 1 | 3 | 0 | 0 | 3 |
| 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a | 0 | 1 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 3 | 0 | 0 | 3 |
| DNA dC->dU-editing enzyme APOBEC-3G isoform 1 | 1 | 0 | 0 | 1 |
| alkaline phosphatase, germ cell type preproprotein | 0 | 1 | 0 | 1 |
| caspase-1 isoform alpha precursor | 1 | 0 | 0 | 1 |
| hypothetical protein SA1422 | 0 | 1 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| DNA dC->dU-editing enzyme APOBEC-3F isoform a | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Prostaglandin E synthase | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Histone deacetylase 3 | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Lysine-specific histone demethylase 1A | 0 | 1 | 0 | 1 |
| D-amino-acid oxidase | 0 | 1 | 0 | 1 |
| Phospholipase A2 | 0 | 1 | 0 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 0 | 2 | 0 | 2 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 2 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Neuronal proto-oncogene tyrosine-protein kinase Src | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Heme oxygenase 1 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Glutathione S-transferase P | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 1 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Microtubule-associated protein tau | 0 | 1 | 0 | 2 |
| 60 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 0 | 1 | 0 | 1 |
| Tissue factor | 0 | 1 | 0 | 1 |
| Tyrosinase | 0 | 1 | 0 | 1 |
| Aminopeptidase N | 0 | 1 | 0 | 1 |
| Aminopeptidase N | 0 | 1 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 1 | 0 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 0 | 2 | 0 | 2 |
| Glycogen synthase kinase-3 beta | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] A | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Acetylcholinesterase | 0 | 1 | 0 | 1 |
| Heme oxygenase 2 | 0 | 1 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Amine oxidase [flavin-containing] B | 0 | 2 | 0 | 2 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-5 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 1 | 1 | 1 | 3 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Glycogen synthase kinase-3 beta | 0 | 1 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Histone deacetylase 4 | 0 | 1 | 0 | 1 |
| Beta-secretase 1 | 0 | 1 | 0 | 1 |
| 10 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Guanine nucleotide-binding protein G | 1 | 0 | 0 | 1 |
| Cholinesterase | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| Lactoylglutathione lyase | 0 | 1 | 0 | 1 |
| Histone acetyltransferase p300 | 0 | 1 | 0 | 1 |
| TAR DNA-binding protein 43 | 2 | 0 | 0 | 2 |
| Serine/threonine-protein kinase PAK 1 | 0 | 1 | 0 | 1 |
| Histone deacetylase 1 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 4 | 0 | 0 | 1 | 1 |
| Sodium/bile acid cotransporter | 0 | 0 | 1 | 1 |
| Nuclear factor erythroid 2-related factor 2 | 0 | 0 | 1 | 1 |
| Thiosulfate sulfurtransferase | 0 | 1 | 0 | 1 |
| Thioredoxin reductase 1, cytoplasmic | 0 | 2 | 0 | 2 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| 10 kDa chaperonin | 0 | 1 | 0 | 1 |
| Thioredoxin reductase 3 | 0 | 2 | 0 | 2 |
| Sortase A | 0 | 1 | 0 | 1 |
| Histone deacetylase 7 | 0 | 1 | 0 | 1 |
| Histone deacetylase 2 | 0 | 2 | 0 | 2 |
| CREB-binding protein | 0 | 1 | 0 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | 0 | 2 | 0 | 2 |
| Cysteine protease | 0 | 1 | 0 | 1 |
| Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
| Histone deacetylase 11 | 0 | 1 | 0 | 1 |
| NACHT, LRR and PYD domains-containing protein 3 | 0 | 1 | 0 | 1 |
| Histone deacetylase 8 | 0 | 2 | 0 | 2 |
| Thioredoxin reductase 2, mitochondrial | 0 | 2 | 0 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 2 | 0 | 2 |
| Histone deacetylase 6 | 0 | 1 | 0 | 1 |
| Histone deacetylase 9 | 0 | 1 | 0 | 1 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Histone deacetylase 5 | 0 | 1 | 0 | 1 |
| Lymphocyte antigen 96 | 0 | 0 | 1 | 1 |
| Beta lactamase (plasmid) | 0 | 1 | 0 | 1 |
| Chain A, Beta-lactamase | 2 | 0 | 0 | 2 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 2 | 0 | 0 | 2 |
| Genome polyprotein | 0 | 1 | 1 | 2 |
| chaperonin-containing TCP-1 beta subunit homolog | 1 | 0 | 0 | 1 |
| hypothetical protein, conserved | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 2 | 0 | 0 | 2 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| eyes absent homolog 2 isoform a | 1 | 0 | 0 | 1 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| relaxin receptor 1 isoform 1 | 1 | 0 | 0 | 1 |
| Flavin reductase (NADPH) | 0 | 0 | 1 | 1 |
| ATP-dependent phosphofructokinase | 1 | 0 | 0 | 1 |
| large T antigen | 0 | 1 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 2 | 0 | 0 | 2 |
| Glucocorticoid receptor | 0 | 4 | 1 | 5 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| nuclear receptor subfamily 1, group I, member 2 | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |