Cerebrospinal Fluid Drainage

Discharge of cerebrospinal fluid through a hole through the skull bone most commonly draining from the nose (CEREBROSPINAL FLUID RHINORRHEA) or the ear (CEREBROSPINAL FLUID OTORRHEA).

Synonym
Spinal Cerebrospinal Fluid Leak, Traumatic
Cerebrospinal Fluid Leak, Post-Traumatic
Spinal Cerebrospinal Fluid Leak
Cerebrospinal Fluid Leak, Traumatic
Cerebrospinal Fluid Leakage
Cerebrospinal Fluid Leakage, Post-Traumatic
Cerebrospinal Fluid Leakage, Spontaneous
Cerebrospinal Fluid Leak, Spontaneous
Spinal Cerebrospinal Fluid Leak, Spontaneous
Cerebrospinal Fluid Drainage, Post-Traumatic
Spinal Cerebrospinal Fluid Leak, Post-Traumatic
Cerebrospinal Fluid Leakage, Traumatic
Cerebrospinal Fluid Leak
Cerebrospinal Fluid Drainage, Traumatic
Cerebrospinal Fluid Drainage, Spontaneous
Cerebrospinal Fluid Drainage

Excerpt	Reference
"Cerebrospinal fluid leakage is the most common complication of endoscopic trans-sphenoidal pituitary surgery."	( Carlin, WV; Darr, A; Hobbs, CG, 2011)
"Cerebrospinal fluid leakage is an immanent risk of cranial surgery with dural opening."	( Hutter, G; Mariani, L; Sailer, MH; Schulz, M; von Felten, S, 2014)
"Cerebrospinal fluid leakage is always the primary complication during the endoscopic endonasal skull base surgery."	( Gu, Y; Liu, T; Sun, C; Xie, T; Zhang, X, 2018)
"Spinal headache and cerebrospinal fluid leak are known complications after intrathecal baclofen treatment in children with cerebral palsy."	( Dixit, D; Imerci, A; McManus, M; Miller, F; Rogers, K; Sees, JP, 2020)
"However, cerebrospinal fluid leakage is still a concern."	( Heng, L; Qu, Y; Zhang, S, 2020)
"Cerebrospinal fluid leakage is a frequent complication after cranial and spinal surgery."	( Kinaci, A; Redegeld, S; Tooren, M; van Doormaal, TPC; van Thoor, S, 2021)

Excerpt	Reference
"If the site of the cerebrospinal fluid leak has been specified and the treatment method is understood by the patient, we think that continuous epidural infusion with physiological saline is safe and effective method of treating cerebrospinal fluid hypovolemia."	( Hashimoto, K, 2011)

Excerpt	Reference
"If the site of the cerebrospinal fluid leak has been specified and the treatment method is understood by the patient, we think that continuous epidural infusion with physiological saline is safe and effective method of treating cerebrospinal fluid hypovolemia."	( Hashimoto, K, 2011)
"One patient presented a cerebrospinal fluid leakage during medical treatment and refused surgery, however this resolved with conservative measures."	( Berriel, MR; Lima, GA; Melo, AS; Rahhal, H; Santos, ML; Taboada, GF, 2016)
"The treatment of cerebrospinal fluid leaks of the lateral recess of the sphenoid sinus (LRSS) faces difficulties due to the deep location of the osseous defect."	( Alves-Belo, JT; Cohen, S; Fernandez-Miranda, JC; Gardner, PA; Mangussi-Gomes, J; Snyderman, CH; Stefko, ST; Truong, HQ; Wang, EW, 2019)
"The incidence of spinal headache/cerebrospinal fluid leak was 31% (107/341), and 81/107 (76%) patients with spinal headache/cerebrospinal fluid leak responded to conservative treatments."	( Dixit, D; Imerci, A; McManus, M; Miller, F; Rogers, K; Sees, JP, 2020)
"Spinal headache and cerebrospinal fluid leak are known complications after intrathecal baclofen treatment in children with cerebral palsy."	( Dixit, D; Imerci, A; McManus, M; Miller, F; Rogers, K; Sees, JP, 2020)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	152 (66.38)	28.8240
2020's	77 (33.62)	9.53

Drug	Relationship Strength	Studies	Trials
methane	low	1	0
salicylic acid	low	5	0
glycolic acid	low	1	0
methanol	low	1	0
phenytoin	low	3	0
acetaminophen	low	1	0
acetazolamide	medium	9	2
theophylline	low	1	0
baclofen	low	8	0
bupivacaine	low	1	0
caffeine	low	1	0
pentetic acid	low	4	0
fentanyl	low	1	0
gentamicin	low	1	0
guaifenesin	low	1	0
lidocaine	low	1	0
ketorolac	low	1	0
khellin	low	1	0
labetalol	low	1	0
milrinone	low	1	0
nimodipine	low	1	0
ondansetron	low	1	0
pentoxifylline	low	1	0
triclosan	low	1	0
trimethoprim	low	1	0
urethane	low	1	0
mitomycin	low	1	0
prednisolone	low	1	0
chloramphenicol	low	1	0
arginine	low	1	0
triamcinolone acetonide	low	1	0
caprolactone	low	1	0
durapatite	low	6	0
bisphenol a-glycidyl methacrylate	low	1	0
fluorescein	low	18	0
enbucrilate	low	2	0
octyl 2-cyanoacrylate	low	3	0
titanium	low	10	0
gadolinium	low	15	0
gold	low	1	0
magnesium sulfate	low	1	0
tricalcium phosphate	low	4	0
fludrocortisone	low	1	0
transferrin	low	12	0
propiconazole	low	19	0
cabergoline	low	1	0
simendan	low	1	0
iopamidol	low	1	0
fluorodeoxyglucose f18	low	1	0
artemisinin	low	1	0
n-hydroxysuccinimide	low	1	0
fibrinogen	medium	12	2
cadusafos	low	1	0
1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid	low	1	0
technetium tc 99m pentetate	low	1	0
n-acetylneuraminic acid	low	1	0
fibrin	low	5	0
inositol 3-phosphate	low	1	0
meropenem	low	1	0
tacrolimus	low	1	0
prostaglandin d2	low	1	0
leuprolide	low	1	0
nitinol	low	1	0
amphotericin b	low	1	0
phenylephrine hydrochloride	low	51	0
oxycodone	low	1	0
bismuth	low	1	0
gadolinium dtpa	low	3	0
ergoline	low	1	0
chlorhexidine	low	1	0
cellulose	low	1	0
chitosan	low	1	0
ro13-9904	low	1	0
interleukin-8	low	1	0
rifampin	low	1	0
eye	low	1	0

Protein Targets (849)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
ATAD5 protein, partial	9	0	0	9
apical membrane antigen 1, AMA1	1	0	0	1
euchromatic histone-lysine N-methyltransferase 2	19	0	0	19
chromobox protein homolog 1	13	0	0	13
DNA polymerase iota isoform a (long)	8	0	0	8
geminin	21	0	0	21
lethal factor (plasmid)	7	0	1	8
botulinum neurotoxin type A	0	0	1	1
botulinum neurotoxin type F, BoNT/F	0	0	1	1
RAR-related orphan receptor gamma	16	0	0	16
GLS protein	9	0	0	9
Microtubule-associated protein tau	6	0	0	6
Smad3	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	9	0	0	9
thyroid stimulating hormone receptor	9	0	0	9
nuclear receptor subfamily 1, group I, member 3	14	0	0	14
progesterone receptor	13	0	0	13
EWS/FLI fusion protein	6	0	0	6
retinoic acid nuclear receptor alpha variant 1	16	0	0	16
retinoid X nuclear receptor alpha	17	0	0	17
estrogen-related nuclear receptor alpha	20	0	0	20
estrogen nuclear receptor alpha	27	0	0	27
peroxisome proliferator activated receptor gamma	12	0	0	12
aryl hydrocarbon receptor	15	0	0	15
thyroid hormone receptor beta isoform 2	18	0	0	18
peripheral myelin protein 22	12	0	0	12
cytochrome P450 3A4 isoform 1	6	0	0	6
Gamma-aminobutyric acid receptor subunit pi	6	4	0	10
ATP-binding cassette sub-family C member 3	0	18	0	18
Multidrug resistance-associated protein 4	0	18	0	18
Solute carrier family 22 member 6	0	3	0	3
Carbonic anhydrase 12	0	4	1	7
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	4	0	4
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Bile salt export pump	0	22	0	22
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Carbonic anhydrase 1	0	6	1	11
Carbonic anhydrase 2	0	6	1	10
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	2	1	4
Cytochrome P450 1A2	0	5	0	6
Prostaglandin G/H synthase 1	0	1	0	1
Carbonic anhydrase 3	0	4	1	7
Cytochrome P450 3A4	0	8	0	9
Cytochrome P450 2D6	0	5	0	5
Cytochrome P450 2C9	0	8	0	8
Polyunsaturated fatty acid lipoxygenase ALOX15	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	6	4	0	10
Sulfotransferase 1A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit delta	6	4	0	10
Gamma-aminobutyric acid receptor subunit gamma-2	6	4	1	11
UDP-glucuronosyltransferase 1-6	0	0	0	1
Glutamate receptor 2	8	0	0	8
Gamma-aminobutyric acid receptor subunit alpha-5	6	4	0	10
Gamma-aminobutyric acid receptor subunit alpha-3	6	4	0	10
Arachidonate 5-lipoxygenase-activating protein	0	2	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	4	1	6
Prostaglandin G/H synthase 1	0	4	0	4
Carbonic anhydrase 6	0	4	1	6
Gamma-aminobutyric acid receptor subunit gamma-1	6	4	0	10
Gamma-aminobutyric acid receptor subunit alpha-2	6	4	0	10
Gamma-aminobutyric acid receptor subunit alpha-4	6	4	0	10
Gamma-aminobutyric acid receptor subunit gamma-3	6	4	0	10
Gamma-aminobutyric acid receptor subunit alpha-6	6	4	0	10
Carbonic anhydrase 5A, mitochondrial	0	4	1	7
Prostaglandin G/H synthase 2	0	3	0	4
Carbonic anhydrase 7	0	4	1	6
Nuclear receptor ROR-gamma	4	0	0	4
Cytochrome P450 2J2	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	6	4	1	11
Gamma-aminobutyric acid receptor subunit beta-3	6	4	0	10
Gamma-aminobutyric acid receptor subunit beta-2	6	4	1	11
Carbonic anhydrase 9	0	4	1	7
GABA theta subunit	6	4	0	10
Canalicular multispecific organic anion transporter 1	0	17	0	17
Carbonic anhydrase 15	0	3	0	4
Carbonic anhydrase 13	0	4	0	5
Gamma-aminobutyric acid receptor subunit epsilon	6	4	0	10
Carbonic anhydrase 14	0	4	1	7
Carbonic anhydrase 5B, mitochondrial	0	4	1	7
toxin B	0	0	0	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Carbonic Anhydrase Ii	0	0	1	1
Chain A, Beta-lactamase	7	0	0	7
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Endochitinase	0	1	0	1
Chain A, Class Iii Chitinase Chia1	0	1	0	1
Chain A, Carbonic anhydrase 13	0	1	0	1
Chain A, Carbonic anhydrase II	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase	0	1	0	1
Chain B, Carbonic anhydrase	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Carbonic anhydrase	0	0	0	1
Carbonic anhydrase	0	1	0	1
thioredoxin reductase	13	0	0	13
GALC protein	5	0	0	5
GLI family zinc finger 3	17	0	0	17
cytochrome P450 family 3 subfamily A polypeptide 4	13	0	0	13
glucocorticoid receptor [Homo sapiens]	22	0	0	22
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
arylsulfatase A	7	0	0	7
Carbonic anhydrase	0	1	0	1
Bloom syndrome protein isoform 1	9	0	0	9
thyroid hormone receptor beta isoform a	6	0	0	6
nuclear factor erythroid 2-related factor 2 isoform 1	17	0	0	17
survival motor neuron protein isoform d	4	0	0	4
muscleblind-like protein 1 isoform 1	1	0	0	1
Carbonic anhydrase	0	1	0	1
Prolyl endopeptidase	0	1	0	1
Carbonic anhydrase-related protein 11	0	1	0	2
Glycogen phosphorylase, muscle form	0	2	0	2
Renin	0	4	0	4
Carbonic anhydrase 2	0	2	0	2
Cathepsin B	0	1	0	1
Steryl-sulfatase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	2
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Cytochrome P450 2C8	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
5-hydroxytryptamine receptor 2A	0	3	0	3
Androgen receptor	0	2	0	2
Translocator protein	0	1	0	1
Cannabinoid receptor 1	0	1	0	1
Cytochrome P450 2B6	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Adenosine receptor A1	0	5	0	7
Serum paraoxonase/arylesterase 1	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	2
Endochitinase	0	1	0	1
Adenosine receptor A2a	0	5	0	9
5-hydroxytryptamine receptor 2B	0	3	0	3
Sodium-dependent serotonin transporter	0	1	0	1
Delta-type opioid receptor	0	3	0	3
Cytochrome P450 2C19	0	4	0	4
Delta-type opioid receptor	0	5	0	5
Mu-type opioid receptor	0	5	1	6
Carbonic anhydrase	0	1	0	1
Kappa-type opioid receptor	0	4	0	4
Carbonic anhydrase	0	1	0	1
D(1A) dopamine receptor	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Carbonic anhydrase	0	1	0	1
D(2) dopamine receptor	0	2	0	2
Cholinesterase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Mu-type opioid receptor	0	4	0	4
Fatty-acid amide hydrolase 1	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Squalene synthase	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase, alpha family	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	2
Carbonic anhydrase	0	1	0	1
Sigma intracellular receptor 2	0	1	0	1
Delta carbonic anhydrase	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	4	0	4
Renin	0	1	0	1
Carbonic anhydrase	0	1	0	1
Endochitinase A1	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	1
Carbonic anhydrase 13	0	2	1	4
Carbonic anhydrase 4	0	2	0	2
Acidic mammalian chitinase	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Carbonic anhydrase 2, isoform A	0	1	0	1
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
Chain A, Cruzipain	4	0	0	4
interleukin 8	5	0	0	5
phosphopantetheinyl transferase	7	0	0	7
farnesoid X nuclear receptor	11	0	0	11
peroxisome proliferator-activated receptor delta	12	0	0	12
vitamin D (1,25- dihydroxyvitamin D3) receptor	15	0	0	15
tumor necrosis factor	1	0	0	1
vitamin D3 receptor isoform VDRA	3	0	0	3
lamin isoform A-delta10	13	0	0	13
Potassium voltage-gated channel subfamily H member 2	0	7	0	7
Aurora kinase B	0	2	0	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	5	0	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	8	0	0	8
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
NFKB1 protein, partial	4	0	0	4
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	6	0	0	6
flap endonuclease 1	6	0	0	6
muscarinic acetylcholine receptor M1	7	0	0	7
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	6	0	0	6
Chain A, Ferritin light chain	6	0	0	6
USP1 protein, partial	9	0	0	9
TDP1 protein	19	0	0	19
AR protein	25	0	0	25
nonstructural protein 1	4	0	0	4
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	12	0	0	12
Histone H2A.x	4	0	0	4
Cellular tumor antigen p53	18	0	0	18
TAR DNA-binding protein 43	7	0	0	7
Dihydroorotate dehydrogenase	0	1	0	1
ATPase family AAA domain-containing protein 5	10	0	0	10
Ataxin-2	12	0	0	12
regulator of G-protein signaling 4	5	0	0	5
67.9K protein	5	0	0	5
activating transcription factor 6	6	0	0	6
D(1A) dopamine receptor	1	0	0	1
histone acetyltransferase KAT2A isoform 1	5	0	0	5
Gamma-aminobutyric acid type B receptor subunit 2	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 2	0	2	0	2
Gamma-aminobutyric acid type B receptor subunit 1	0	2	1	3
Gamma-aminobutyric acid type B receptor subunit 1	0	1	0	1
glp-1 receptor, partial	8	0	0	8
hypoxia-inducible factor 1 alpha subunit	8	0	0	8
SMAD family member 2	8	0	0	8
SMAD family member 3	8	0	0	8
TSHR protein	1	0	0	1
estrogen receptor 2 (ER beta)	8	0	0	8
pregnane X nuclear receptor	17	0	0	17
IDH1	7	0	0	7
thyroid stimulating hormone receptor	8	0	0	8
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
v-jun sarcoma virus 17 oncogene homolog (avian)	6	0	0	6
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	3	0	0	3
heat shock protein beta-1	6	0	0	6
DNA polymerase eta isoform 1	1	0	0	1
Alpha-synuclein	3	1	0	4
Potassium channel subfamily K member 3	0	2	0	2
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	1	3	4
Potassium channel subfamily K member 9	0	1	0	1
acetylcholinesterase	7	0	0	7
cytochrome P450 2D6	10	0	0	10
5-hydroxytryptamine receptor 2B	0	5	1	6
Spike glycoprotein	10	0	0	10
Histamine H3 receptor	0	1	0	1
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
DNA polymerase beta	1	0	0	1
nuclear receptor ROR-gamma isoform 1	7	0	0	7
DNA polymerase kappa isoform 1	5	0	0	5
Cholinesterase	0	2	0	2
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	3	0	3
Adenosine receptor A3	0	3	0	3
Replicase polyprotein 1ab	0	3	0	3
Amine oxidase [flavin-containing] A	0	2	0	2
Acetylcholinesterase	0	3	0	3
Amine oxidase [flavin-containing] B	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	5	0	5
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2a	0	4	3	9
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A2b	0	3	0	5
Adenosine receptor A1	0	3	2	9
Vasopressin V2 receptor	0	0	0	2
Serine/threonine-protein kinase mTOR	0	2	0	2
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	2	0	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	2
Chitotriosidase-1	0	4	1	5
Serine-protein kinase ATM	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
Adenosine receptor A2b	0	1	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	3	4
Endochitinase B1	0	4	1	5
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	1	0	1
G	8	0	0	8
streptokinase A precursor	0	0	2	2
Dihydroxyacetone phosphate acyltransferase	0	0	0	1
Interferon beta	10	0	0	10
HLA class I histocompatibility antigen, B alpha chain	8	0	0	8
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Inositol hexakisphosphate kinase 1	8	0	0	8
Methionine--tRNA ligase, mitochondrial	0	0	1	1
cytochrome P450 2C9, partial	8	0	0	8
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
Luciferase	4	0	0	4
acid sphingomyelinase	1	0	0	1
PAX8	0	0	0	1
15-lipoxygenase, partial	4	0	0	4
pregnane X receptor	2	0	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	4	0	0	4
PINK1	2	0	0	2
glucocerebrosidase	1	0	0	1
Parkin	3	0	0	3
heat shock protein 90	0	0	1	1
caspase-3	3	0	0	3
calcineurin A1, putative	0	0	1	1
cytochrome P450 2D6 isoform 1	2	0	0	2
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
cytochrome P450 2C9 precursor	2	0	0	2
perilipin-5	0	1	0	1
perilipin-1	0	1	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	4	0	0	4
transcriptional regulator ERG isoform 3	3	0	0	3
huntingtin isoform 2	1	0	0	1
importin subunit beta-1 isoform 1	2	0	0	2
mitogen-activated protein kinase 1	3	0	0	3
ubiquitin-conjugating enzyme E2 N	0	1	0	1
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
protein AF-9 isoform a	0	0	0	1
snurportin-1	2	0	0	2
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
bcl-2-related protein A1	0	1	0	1
urokinase plasminogen activator surface receptor precursor	2	0	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	1	0	1
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Synaptojanin-2	0	1	0	1
Solute carrier family 22 member 2	0	2	0	2
Solute carrier family 22 member 1	0	5	0	5
Polyunsaturated fatty acid lipoxygenase ALOX15B	4	0	0	4
Synaptojanin-1	0	1	0	1
Solute carrier family 22 member 3	0	2	0	2
Glutathione reductase, mitochondrial	0	1	0	2
Integrin beta-3	1	1	0	2
72 kDa type IV collagenase	0	1	0	1
Integrin alpha-IIb	1	1	0	2
Matrix metalloproteinase-9	0	1	0	1
Trypanothione reductase	0	1	0	1
Histamine H2 receptor	5	0	0	5
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	2	0	2
Rap guanine nucleotide exchange factor 4	2	0	0	2
Multidrug and toxin extrusion protein 1	0	3	0	3
Spermine oxidase	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	4	4
ATP-dependent translocase ABCB1	0	1	0	1
D(2) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	1	0	1
Kappa-type opioid receptor	0	3	0	3
Histamine H1 receptor	0	1	0	1
Mu-type opioid receptor	0	3	2	5
D(3) dopamine receptor	0	1	0	1
Delta-type opioid receptor	0	2	1	3
Kappa-type opioid receptor	0	2	1	3
Mu-type opioid receptor	0	1	1	2
Sigma non-opioid intracellular receptor 1	0	5	0	5
Sigma non-opioid intracellular receptor 1	0	2	0	2
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
thyrotropin-releasing hormone receptor	2	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
ras-related protein Rab-9A	1	0	0	1
Fatty acid-binding protein, liver	0	2	0	2
Albumin	0	2	1	3
Fatty acid-binding protein, intestinal	0	1	1	2
Caspase-1	0	2	0	2
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Caspase-9	0	1	0	1
Cell division control protein 42 homolog	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	1	0	1
Serine/threonine-protein kinase PAK 1	0	1	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	4	0	0	4
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
Cytochrome P450 1B1	0	1	0	1
Beta-1 adrenergic receptor	0	0	1	1
Beta-2 adrenergic receptor	0	2	1	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Beta-1 adrenergic receptor	0	2	1	3
Beta-3 adrenergic receptor	0	0	1	1
5-hydroxytryptamine receptor 1A	0	4	0	4
Alpha-2B adrenergic receptor	0	0	1	1
Alpha-2C adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	1	1	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Alpha-1D adrenergic receptor	0	2	1	3
5-hydroxytryptamine receptor 1B	0	3	0	3
Alpha-1A adrenergic receptor	0	0	1	1
Alpha-1B adrenergic receptor	0	0	1	1
Sodium-dependent dopamine transporter	0	2	0	2
Beta-2 adrenergic receptor	0	0	1	1
Heparanase	0	0	1	1
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	1	0	1
Potassium voltage-gated channel subfamily A member 5	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	2	0	3
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	2	0	2
Potassium voltage-gated channel subfamily D member 2	0	1	0	1
Potassium channel subfamily K member 18	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	2	0	2
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase type 2	0	0	1	2
Metallo-beta-lactamase VIM-11	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Metallo-beta-lactamase VIM-19	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase TEM	0	0	0	1
B2 metallo-beta-lactamase	0	0	0	1
Metallo-beta-lactamase VIM-13	0	0	0	1
Metallo-beta-lactamase VIM-2	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Metallo-beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	1	2
Metallo-b-lactamase	0	0	0	1
Beta-lactamase IMP-1	0	0	0	1
BlaVIM-1	0	0	0	1
Beta-lactamase	0	0	0	1
Carbapenem-hydrolyzing beta-lactamase KPC	0	0	0	1
Histamine H3 receptor	0	0	0	1
Beta-lactamase class B VIM-2	0	0	1	2
Beta-lactamase	0	0	0	1
Beta-lactamase VIM-1	0	0	0	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
Phosphodiesterase	0	3	0	3
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
Vpr	3	0	0	3
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Aurora kinase A	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	2	0	2
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	2
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Dual specificity protein kinase TTK	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	3	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	5	0	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	3	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	4	0	4
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Inner centromere protein	0	1	0	1
Phosphodiesterase	0	1	0	1
Fumarate hydratase	2	0	0	2
polyprotein	2	0	0	2
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Sialidase-4	0	1	0	1
Sialidase-1	0	1	0	1
Sialidase-3	0	1	0	1
Sialidase-2	0	1	0	1
Bromodomain-containing protein 4	0	0	0	1
Protein cereblon	0	0	0	1
endonuclease IV	5	0	0	5
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
peripheral myelin protein 22 isoform 1	4	0	0	4
M-phase phosphoprotein 8	2	0	0	2
neuropeptide S receptor isoform A	1	0	0	1
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Cannabinoid receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	1	0	1
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
5-hydroxytryptamine receptor 3E	0	1	1	3
5-hydroxytryptamine receptor 3A	0	0	1	1
5-hydroxytryptamine receptor 3B	0	1	1	3
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
5-hydroxytryptamine receptor 1A	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-4	1	1	0	2
Beta-2 adrenergic receptor	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Beta-1 adrenergic receptor	0	1	0	1
D	0	1	0	1
D(3) dopamine receptor	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Interleukin-6 receptor subunit alpha	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
D(1B) dopamine receptor	0	1	0	1
Beta-3 adrenergic receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
5-hydroxytryptamine receptor 2A	0	1	0	1
5-hydroxytryptamine receptor 1D	0	1	0	1
Cholecystokinin receptor type A	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
D(4) dopamine receptor	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	2	1	3
Alpha-1A adrenergic receptor	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
5-hydroxytryptamine receptor 3A	0	2	1	4
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
5-hydroxytryptamine receptor 6	0	0	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Thyrotropin-releasing hormone receptor	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Glycine receptor subunit alpha-4	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3D	0	1	1	3
5-hydroxytryptamine receptor 3C	0	1	1	3
5-hydroxytryptamine receptor 3B	0	1	0	1
5-hydroxytryptamine receptor 3B	0	2	1	3
Histamine H3 receptor	0	1	0	1
Leukotriene B4 receptor 1	0	1	0	1
Nischarin	0	1	0	1
Acetylcholinesterase	0	1	0	1
Kappa-type opioid receptor	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	2	0	0	2
dopamine D1 receptor	2	0	0	2
vasopressin V1b receptor	1	0	0	1
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
relaxin receptor 1 isoform 1	1	0	0	1
Tumor necrosis factor	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Inositol monophosphatase 1	3	0	0	3
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Gamma-aminobutyric acid	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Sodium channel protein type 1 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Glucocorticoid receptor	0	4	1	10
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Glycine receptor subunit alpha-1	0	4	0	4
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Androgen receptor	0	2	0	2
Glutamine synthetase	0	0	1	1
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Histamine H1 receptor	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
Guanine nucleotide-binding protein G	2	0	0	2
heat shock protein 90, putative	0	0	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	2
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	0	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	1
Solute carrier organic anion transporter family member 2B1	0	2	0	2
NH(3)-dependent NAD(+) synthetase	0	2	0	2
60 kDa heat shock protein, mitochondrial	0	1	0	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	1	0	1
10 kDa heat shock protein, mitochondrial	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	3	0	3
DNA-directed RNA polymerase subunit beta	0	1	0	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	3
Solute carrier organic anion transporter family member 1B1	0	3	0	4
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Polyphenol oxidase 2	0	1	0	2
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Polymerase acidic protein	0	0	1	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
Cytochrome P450 3A5	0	1	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Phospholipase A-2-activating protein	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, enoyl-acyl carrier reductase	0	1	0	1
Chain C, enoyl-acyl carrier reductase	0	1	0	1
Chain A, Repressor	0	0	1	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Caspase-7	1	0	0	1
caspase-3	1	0	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Transthyretin	0	1	1	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Endoplasmic reticulum chaperone BiP	0	1	0	1
Carbonyl reductase [NADPH] 1	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	0	2	0	2
Enoyl-acyl carrier reductase	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	2	0	2
Enoyl-ACP reductase II	0	1	0	1
Chain A, Dihydrofolate Reductase	0	0	1	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, dihydrofolate reductase (DHFR)	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Chain A, Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase type 1	0	1	0	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	2	0	2
Dihydrofolate reductase type 1 from Tn4003	0	1	0	1
Dipeptidyl peptidase 4	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Metabotropic glutamate receptor 5	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Trace amine-associated receptor 5	0	0	1	1
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	2
Protein-arginine deiminase type-4	0	1	0	1
Dihydrofolate reductase	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Cerebrospinal Fluid Drainage

Synonyms(16)

Research Excerpts

Overview

Context

Treatment

Research

Studies (229)

Protein Targets (849)

Cerebrospinal Fluid Drainage

Synonyms(16)

Research Excerpts

Overview

Context

Treatment

Research

Studies (229)

Drugs Studied (91)

Protein Targets (849)