| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| Proteasome subunit beta type-11 | 0 | 0 | 0 | 1 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| RAR-related orphan receptor gamma | 1 | 0 | 0 | 1 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| USP1 protein, partial | 1 | 0 | 0 | 1 |
| NFKB1 protein, partial | 1 | 0 | 0 | 1 |
| TDP1 protein | 1 | 0 | 0 | 1 |
| GLI family zinc finger 3 | 1 | 0 | 0 | 1 |
| Microtubule-associated protein tau | 1 | 0 | 0 | 1 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| AR protein | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| estrogen receptor 2 (ER beta) | 1 | 0 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | 1 | 0 | 0 | 1 |
| progesterone receptor | 1 | 0 | 0 | 1 |
| NADPH oxidase 1 | 0 | 1 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 1 | 0 | 0 | 1 |
| glucocorticoid receptor [Homo sapiens] | 1 | 0 | 0 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | 1 | 0 | 0 | 1 |
| retinoid X nuclear receptor alpha | 1 | 0 | 0 | 1 |
| estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
| farnesoid X nuclear receptor | 1 | 0 | 0 | 1 |
| pregnane X nuclear receptor | 1 | 0 | 0 | 1 |
| estrogen nuclear receptor alpha | 2 | 0 | 0 | 2 |
| G | 1 | 0 | 0 | 1 |
| cytochrome P450 2D6 | 1 | 0 | 0 | 1 |
| polyprotein | 1 | 0 | 0 | 1 |
| 67.9K protein | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
| Snq2p | 0 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| IDH1 | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 1 | 0 | 0 | 1 |
| Adenylate cyclase type 1 | 0 | 2 | 0 | 2 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
| Histone H2A.x | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| Spike glycoprotein | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
| chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 1 | 0 | 0 | 1 |
| histone deacetylase 9 isoform 3 | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| serine/threonine-protein kinase mTOR isoform 1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| histone acetyltransferase KAT2A isoform 1 | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
| Proteasome subunit alpha type-7 | 0 | 0 | 0 | 1 |
| Solute carrier family 22 member 1 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Transmembrane protease serine 2 | 0 | 1 | 1 | 2 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 1 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 1 | 0 | 1 |
| Transient receptor potential cation channel subfamily V member 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 4 | 0 | 2 | 0 | 2 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Epidermal growth factor receptor | 0 | 1 | 0 | 1 |
| Interferon beta | 1 | 0 | 0 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Albumin | 0 | 0 | 1 | 1 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 0 | 1 | 0 | 1 |
| Receptor tyrosine-protein kinase erbB-2 | 0 | 1 | 0 | 1 |
| Cellular tumor antigen p53 | 1 | 0 | 0 | 1 |
| Major prion protein | 0 | 0 | 1 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 0 | 1 | 1 |
| Tyrosine-protein kinase Fyn | 0 | 1 | 0 | 1 |
| Procathepsin L | 0 | 1 | 1 | 2 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| 5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Replicase polyprotein 1a | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Cys-loop ligand-gated ion channel | 0 | 1 | 0 | 1 |
| Calmodulin-1 | 0 | 2 | 1 | 3 |
| Replicase polyprotein 1ab | 0 | 1 | 1 | 2 |
| Cytochrome P450 2D6 | 0 | 1 | 1 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C9 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 2 | 0 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 3 |
| 5-hydroxytryptamine receptor 2A | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Sphingomyelin phosphodiesterase | 0 | 1 | 0 | 1 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| D | 0 | 2 | 0 | 2 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 1A | 0 | 2 | 0 | 2 |
| Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
| D(2) dopamine receptor | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Proteasome subunit beta type-1 | 0 | 0 | 0 | 1 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| D(1A) dopamine receptor | 0 | 2 | 0 | 3 |
| D(4) dopamine receptor | 0 | 2 | 0 | 3 |
| D(1B) dopamine receptor | 0 | 1 | 0 | 2 |
| Adenylate cyclase type 3 | 0 | 2 | 0 | 2 |
| Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
| UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
| Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 0 | 2 | 0 | 2 |
| Alpha-1D adrenergic receptor | 0 | 2 | 0 | 2 |
| D(1B) dopamine receptor | 0 | 2 | 0 | 2 |
| Proteasome subunit alpha type-1 | 0 | 0 | 0 | 1 |
| Proteasome subunit alpha type-2 | 0 | 0 | 0 | 1 |
| Proteasome subunit alpha type-3 | 0 | 0 | 0 | 1 |
| Proteasome subunit alpha type-4 | 0 | 0 | 0 | 1 |
| Adenylate cyclase type 2 | 0 | 2 | 0 | 2 |
| Adenylate cyclase type 4 | 0 | 2 | 0 | 2 |
| Proteasome subunit beta type-8 | 0 | 0 | 0 | 1 |
| Proteasome subunit beta type-9 | 0 | 0 | 0 | 1 |
| Proteasome subunit alpha type-5 | 0 | 0 | 0 | 1 |
| Proteasome subunit beta type-4 | 0 | 0 | 0 | 1 |
| Proteasome subunit beta type-6 | 0 | 0 | 0 | 1 |
| Proteasome subunit beta type-5 | 0 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2C | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
| Trypanothione reductase | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
| D(4) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 1 | 0 | 1 |
| Sodium-dependent serotonin transporter | 0 | 2 | 0 | 2 |
| Melanocortin receptor 4 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Melanocortin receptor 5 | 0 | 2 | 0 | 2 |
| Pleiotropic ABC efflux transporter of multiple drugs | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Histamine H1 receptor | 0 | 2 | 0 | 2 |
| Mu-type opioid receptor | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 2 | 0 | 3 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Adenylate cyclase type 8 | 0 | 2 | 0 | 2 |
| Proteasome subunit beta type-10 | 0 | 0 | 0 | 1 |
| Delta-type opioid receptor | 0 | 2 | 0 | 2 |
| Kappa-type opioid receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Melanocortin receptor 3 | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Histamine H2 receptor | 1 | 0 | 0 | 1 |
| Proteasome subunit beta type-3 | 0 | 0 | 0 | 1 |
| Proteasome subunit beta type-2 | 0 | 0 | 0 | 1 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| 5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 1 | 0 | 1 |
| Gastrin/cholecystokinin type B receptor | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 1 | 1 | 1 | 3 |
| Proteasome subunit alpha type-6 | 0 | 0 | 1 | 2 |
| D(2) dopamine receptor | 0 | 2 | 0 | 3 |
| Calmodulin | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| Aldehyde oxidase 1 | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Sodium channel protein type 7 subunit alpha | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| Adenylate cyclase type 6 | 0 | 2 | 0 | 2 |
| Adenylate cyclase type 5 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 1 | 0 | 1 | 0 | 1 |
| Aldehyde oxidase | 0 | 2 | 0 | 2 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
| Glutamate receptor ionotropic, NMDA 2A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2B | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2C | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 2D | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 3 group C member 3 | 0 | 2 | 0 | 2 |
| Adenylyl cyclase 7 | 0 | 2 | 0 | 2 |
| Proteasome subunit alpha-type 8 | 0 | 0 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3B | 0 | 1 | 0 | 1 |
| GABA theta subunit | 1 | 0 | 0 | 1 |
| Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 1 | 0 | 1 |
| D | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Proteasome subunit beta type-7 | 0 | 0 | 0 | 1 |
| Ataxin-2 | 1 | 0 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Angiotensin-converting enzyme 2 | 0 | 1 | 1 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Glutamate receptor ionotropic, NMDA 3A | 0 | 1 | 0 | 1 |
| Sodium channel protein type 11 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 8 subunit alpha | 0 | 1 | 0 | 1 |
| Histamine H3 receptor | 0 | 1 | 0 | 1 |
| Sodium channel protein type 10 subunit alpha | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
| N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | 0 | 1 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |