Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
Chain A, Cruzipain | 1 | 0 | 0 | 1 |
interleukin 8 | 1 | 0 | 0 | 1 |
phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
GLS protein | 1 | 0 | 0 | 1 |
glucocorticoid receptor [Homo sapiens] | 3 | 0 | 0 | 3 |
farnesoid X nuclear receptor | 3 | 0 | 0 | 3 |
peroxisome proliferator-activated receptor delta | 2 | 0 | 0 | 2 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 1 | 0 | 0 | 1 |
tumor necrosis factor | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 3 | 0 | 0 | 3 |
peripheral myelin protein 22 | 1 | 0 | 0 | 1 |
lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
Cytochrome P450 1A2 | 0 | 1 | 0 | 1 |
Cytochrome P450 3A4 | 0 | 4 | 0 | 4 |
Cytochrome P450 2D6 | 0 | 1 | 0 | 1 |
Cytochrome P450 2C9 | 0 | 4 | 0 | 4 |
Cytochrome P450 2C19 | 0 | 2 | 0 | 2 |
Nuclear receptor ROR-gamma | 1 | 0 | 0 | 1 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 2 | 0 | 2 |
Aurora kinase B | 0 | 1 | 0 | 1 |
Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 3 | 0 | 3 |
Chain A, BCL-2-RELATED PROTEIN A1 | 0 | 0 | 1 | 1 |
acetylcholinesterase | 1 | 0 | 0 | 1 |
GLI family zinc finger 3 | 3 | 0 | 0 | 3 |
apical membrane antigen 1, AMA1 | 1 | 0 | 0 | 1 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 5 | 0 | 0 | 5 |
retinoic acid nuclear receptor alpha variant 1 | 3 | 0 | 0 | 3 |
retinoid X nuclear receptor alpha | 3 | 0 | 0 | 3 |
pregnane X nuclear receptor | 3 | 0 | 0 | 3 |
estrogen nuclear receptor alpha | 3 | 0 | 0 | 3 |
G | 5 | 0 | 0 | 5 |
cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
unnamed protein product | 0 | 1 | 0 | 1 |
chromobox protein homolog 1 | 1 | 0 | 0 | 1 |
transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
heat shock protein HSP 90-alpha isoform 2 | 0 | 0 | 0 | 1 |
DNA polymerase iota isoform a (long) | 2 | 0 | 0 | 2 |
geminin | 2 | 0 | 0 | 2 |
cytochrome P450 3A4 isoform 1 | 1 | 0 | 0 | 1 |
bcl-2-like protein 11 isoform 1 | 0 | 0 | 1 | 1 |
Gamma-aminobutyric acid receptor subunit pi | 1 | 0 | 0 | 1 |
Histone deacetylase 3 | 0 | 1 | 0 | 1 |
ATP-binding cassette sub-family C member 3 | 0 | 4 | 0 | 4 |
Multidrug resistance-associated protein 4 | 0 | 4 | 0 | 4 |
Bile salt export pump | 0 | 4 | 0 | 4 |
Rap guanine nucleotide exchange factor 3 | 2 | 0 | 0 | 2 |
Chymotrypsinogen A | 0 | 1 | 0 | 1 |
Beta-lactamase | 0 | 1 | 0 | 1 |
Interferon beta | 5 | 0 | 0 | 5 |
HLA class I histocompatibility antigen, B alpha chain | 5 | 0 | 0 | 5 |
Cellular tumor antigen p53 | 3 | 0 | 0 | 3 |
Steroid 17-alpha-hydroxylase/17,20 lyase | 0 | 2 | 0 | 2 |
Heme oxygenase 1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Lanosterol 14-alpha demethylase | 0 | 1 | 3 | 4 |
Aromatase | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit beta-1 | 1 | 0 | 0 | 1 |
Cytochrome P450 11B1, mitochondrial | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit delta | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 1 | 0 | 0 | 1 |
Cytochrome P450 11B2, mitochondrial | 0 | 2 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 1 | 0 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 1 | 0 | 0 | 1 |
Heme oxygenase 2 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 1 | 0 | 0 | 1 |
Malate dehydrogenase, cytoplasmic | 0 | 1 | 0 | 1 |
Histone deacetylase 4 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-3 | 1 | 0 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-2 | 1 | 0 | 0 | 1 |
Cytochrome P450 144 | 0 | 0 | 3 | 3 |
Steroid C26-monooxygenase | 0 | 0 | 3 | 3 |
Steroid C26-monooxygenase | 0 | 0 | 3 | 3 |
Mycocyclosin synthase | 0 | 0 | 1 | 1 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
Lanosterol 14-alpha demethylase | 0 | 0 | 1 | 1 |
TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
Histone deacetylase 1 | 0 | 1 | 0 | 1 |
Lanosterol 14-alpha demethylase | 0 | 1 | 1 | 2 |
Sterol 14-alpha demethylase | 0 | 0 | 3 | 3 |
Sterol 14-alpha demethylase | 0 | 2 | 2 | 4 |
Histone deacetylase 7 | 0 | 1 | 0 | 1 |
GABA theta subunit | 1 | 0 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 5 | 0 | 0 | 5 |
Histone deacetylase 2 | 0 | 1 | 0 | 1 |
Canalicular multispecific organic anion transporter 1 | 0 | 4 | 0 | 4 |
Polyamine deacetylase HDAC10 | 0 | 1 | 0 | 1 |
Histone deacetylase 11 | 0 | 1 | 0 | 1 |
14-alpha sterol demethylase | 0 | 0 | 3 | 3 |
Histone deacetylase 8 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit epsilon | 1 | 0 | 0 | 1 |
Histone deacetylase 6 | 0 | 1 | 0 | 1 |
Histone deacetylase 9 | 0 | 1 | 0 | 1 |
Histone deacetylase 5 | 0 | 1 | 0 | 1 |
cytochrome P450 2C9, partial | 5 | 0 | 0 | 5 |
heat shock protein 90, putative | 0 | 0 | 0 | 1 |
likely tRNA 2'-phosphotransferase | 0 | 1 | 0 | 1 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 1 | 0 | 0 | 1 |
Skn7p | 0 | 0 | 0 | 1 |
AR protein | 3 | 0 | 0 | 3 |
EWS/FLI fusion protein | 3 | 0 | 0 | 3 |
nonstructural protein 1 | 1 | 0 | 0 | 1 |
heat shock protein 90 | 0 | 0 | 1 | 1 |
calcineurin A1, putative | 0 | 0 | 1 | 1 |
serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
HSP40, subfamily A [Plasmodium falciparum 3D7] | 0 | 0 | 0 | 1 |
Spike glycoprotein | 3 | 0 | 0 | 3 |
hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
RAR-related orphan receptor gamma | 2 | 0 | 0 | 2 |
Fumarate hydratase | 2 | 0 | 0 | 2 |
GALC protein | 1 | 0 | 0 | 1 |
estrogen receptor 2 (ER beta) | 2 | 0 | 0 | 2 |
nuclear receptor subfamily 1, group I, member 3 | 2 | 0 | 0 | 2 |
estrogen-related nuclear receptor alpha | 2 | 0 | 0 | 2 |
polyprotein | 2 | 0 | 0 | 2 |
activating transcription factor 6 | 1 | 0 | 0 | 1 |
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 1 | 0 | 0 | 1 |
thyroid hormone receptor beta isoform 2 | 2 | 0 | 0 | 2 |
heat shock protein beta-1 | 1 | 0 | 0 | 1 |
Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
Glutamate receptor 2 | 2 | 0 | 0 | 2 |
Sterol 14-alpha-demethylase | 0 | 0 | 2 | 2 |
SMAD family member 2 | 1 | 0 | 0 | 1 |
SMAD family member 3 | 1 | 0 | 0 | 1 |
TDP1 protein | 1 | 0 | 0 | 1 |
caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
progesterone receptor | 1 | 0 | 0 | 1 |
peroxisome proliferator activated receptor gamma | 1 | 0 | 0 | 1 |
caspase-3 | 1 | 0 | 0 | 1 |
thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
14-alpha sterol demethylase | 0 | 0 | 2 | 2 |
ATPase family AAA domain-containing protein 5 | 1 | 0 | 0 | 1 |
Ataxin-2 | 1 | 0 | 0 | 1 |
14-alpha sterol demethylase | 0 | 0 | 2 | 2 |
mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1F | 0 | 1 | 0 | 1 |
Cholesterol side-chain cleavage enzyme, mitochondrial | 0 | 0 | 1 | 1 |
Cytochrome P450 2B6 | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1D | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1S | 0 | 1 | 0 | 1 |
Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
Cholesterol 24-hydroxylase | 0 | 2 | 1 | 3 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |