Page last updated: 2024-09-27

Central Nervous System Fungal Infections

MYCOSES of the brain, spinal cord, and meninges which may result in ENCEPHALITIS; MENINGITIS, FUNGAL; MYELITIS; BRAIN ABSCESS; and EPIDURAL ABSCESS. Certain types of fungi may produce disease in immunologically normal hosts, while others are classified as opportunistic pathogens, causing illness primarily in immunocompromised individuals (e.g., ACQUIRED IMMUNODEFICIENCY SYNDROME).

Synonyms(6)

Synonym
Central Nervous System Fungal Infections
CNS Fungal Infections
Mycoses, Central Nervous System
Fungal Infections, Central Nervous System
Infections, Fungal, Central Nervous System
Central Nervous System Mycoses

Research Excerpts

Treatment

ExcerptReference
"39 patients with CNS fungal infections treated in neurology service during the last 3 years were included and a detailed medical history and clinical examination were undertaken."( Agarwal, R; Kalita, J; Marak, RS; Misra, UK, 2012)

Research

Studies (173)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's3 (1.73)12.5806
2000's80 (46.24)18.1394
2010's74 (42.77)28.8240
2020's16 (9.25)9.53
DrugIndicatedRelationship StrengthStudiesTrials
adenine0low10
salicylic acid0low10
lactic acid0low10
dimethyl sulfoxide0low10
formaldehyde0low10
iodine0low10
urea0low10
amantadine0low10
azathioprine0low10
valproic acid0low10
fluconazole0medium201
flucytosine0medium81
ketoconazole0low20
mitoxantrone0low10
prednisolone0low10
prednisone0low20
galactose0medium11
cytarabine0low10
fusarium0low10
methamphetamine0low10
vancomycin0low20
trolamine salicylate0low10
selegiline0low10
propiconazole0low30
itraconazole0medium221
glucose, (beta-d)-isomer0low10
cephalosporin c0low10
triazoles0medium531
voriconazole0low410
carbapenems0low10
deferasirox0low10
deoxycholic acid0low10
trimethoprim, sulfamethoxazole drug combination0low30
epiglucan0medium61
laminaran0medium11
cocaine0low10
posaconazole0medium171
l 743,8720low70
micafungin0low40
terbinafine0low40
laccase0low10
galactomannan0medium11
amphotericin b0medium701
isavuconazole0low20
phosphatidylcholines0low40
amphotericin b, deoxycholate drug combination0low10
pci 327650low10
mannans0medium21
piperidines0low10
warfarin0low10

Protein Targets (881)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
Chain A, MTA/SAH nucleosidase0101
Chain A, Ribosome-inactivating protein alpha-trichosanthin0011
Chain A, Ricin A chain0011
Chain A, Ribosome-inactivating protein 30011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
Chain A, Phenylethanolamine N-methyltransferase0011
RAR-related orphan receptor gamma150015
TDP1 protein120012
AR protein130013
nuclear receptor subfamily 1, group I, member 3110011
cytochrome P450 family 3 subfamily A polypeptide 4110011
glucocorticoid receptor [Homo sapiens]130013
estrogen-related nuclear receptor alpha130013
pregnane X nuclear receptor120012
estrogen nuclear receptor alpha170017
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a8008
nuclear factor erythroid 2-related factor 2 isoform 26006
heat shock protein beta-14004
importin subunit beta-1 isoform 13003
snurportin-13003
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 12002
lamin isoform A-delta10100010
Voltage-dependent calcium channel gamma-2 subunit9009
Bile salt export pump013013
Cyclin-dependent kinase 10112
Heat shock protein HSP 90-beta0101
Glutamate receptor 29009
Xanthine dehydrogenase/oxidase0101
TAR DNA-binding protein 434105
Protein mono-ADP-ribosyltransferase PARP150101
Leucine-rich repeat serine/threonine-protein kinase 20202
ATPase family AAA domain-containing protein 56006
Ataxin-28008
acetylcholinesterase5005
thioredoxin reductase5005
NFKB1 protein, partial2002
GLI family zinc finger 3120012
signal transducer and activator of transcription 6, interleukin-4 induced1001
thyroid stimulating hormone receptor1001
regulator of G-protein signaling 43003
EWS/FLI fusion protein100010
putative alpha-glucosidase1001
euchromatic histone-lysine N-methyltransferase 25005
thyroid hormone receptor beta isoform 2100010
peripheral myelin protein 226006
histone acetyltransferase KAT2A isoform 14004
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0203
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Matrix protein 20112
Matrix protein 20123
Glutamate receptor ionotropic, NMDA 1 0202
Spike glycoprotein5005
Glutamate receptor ionotropic, NMDA 2A 0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0202
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, NMDA 2B0101
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 2D0202
Solute carrier family 22 member 10101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0202
Multidrug and toxin extrusion protein 10202
Solute carrier family 22 member 20101
Glutamate receptor ionotropic, NMDA 3A0202
ATP-dependent phosphofructokinase3003
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, Cruzipain1001
interleukin 82002
phosphopantetheinyl transferase5005
GLS protein2002
farnesoid X nuclear receptor8008
peroxisome proliferator-activated receptor delta6006
vitamin D (1,25- dihydroxyvitamin D3) receptor4004
tumor necrosis factor1001
vitamin D3 receptor isoform VDRA4004
nuclear factor erythroid 2-related factor 2 isoform 1120012
Cytochrome P450 1A20202
Cytochrome P450 3A4010012
Cytochrome P450 2D60404
Cytochrome P450 2C9 0708
Cytochrome P450 2C190304
Nuclear receptor ROR-gamma4004
Potassium voltage-gated channel subfamily H member 20909
Aurora kinase B0112
Broad substrate specificity ATP-binding cassette transporter ABCG20506
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Ferritin light chain4004
SMAD family member 24004
ATAD5 protein, partial2002
Fumarate hydratase6006
SMAD family member 34004
Microtubule-associated protein tau1001
thioredoxin glutathione reductase2002
retinoic acid nuclear receptor alpha variant 1160016
retinoid X nuclear receptor alpha120012
G8008
polyprotein6006
P531001
peroxisome proliferator activated receptor gamma7007
arylsulfatase A2002
IDH13003
aryl hydrocarbon receptor4004
thyroid stimulating hormone receptor4004
activating transcription factor 64004
v-jun sarcoma virus 17 oncogene homolog (avian)7007
Histone H2A.x5005
Bloom syndrome protein isoform 12002
peripheral myelin protein 22 isoform 11001
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a3003
DNA polymerase iota isoform a (long)7007
geminin6006
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 13003
M-phase phosphoprotein 82002
muscleblind-like protein 1 isoform 12002
muscarinic acetylcholine receptor M12002
Gamma-aminobutyric acid receptor subunit pi3003
ATP-binding cassette sub-family C member 30909
Multidrug resistance-associated protein 40909
Bile salt export pump0404
Interferon beta120012
HLA class I histocompatibility antigen, B alpha chain 8008
Cellular tumor antigen p53120012
Gamma-aminobutyric acid receptor subunit beta-13003
Gamma-aminobutyric acid receptor subunit delta3003
Gamma-aminobutyric acid receptor subunit gamma-23003
Gamma-aminobutyric acid receptor subunit alpha-53003
Gamma-aminobutyric acid receptor subunit alpha-33003
Gamma-aminobutyric acid receptor subunit gamma-13003
Gamma-aminobutyric acid receptor subunit alpha-23003
Gamma-aminobutyric acid receptor subunit alpha-43003
Gamma-aminobutyric acid receptor subunit gamma-33003
Gamma-aminobutyric acid receptor subunit alpha-63003
Gamma-aminobutyric acid receptor subunit alpha-13003
Gamma-aminobutyric acid receptor subunit beta-33003
Gamma-aminobutyric acid receptor subunit beta-23003
GABA theta subunit3003
Inositol hexakisphosphate kinase 18008
Canalicular multispecific organic anion transporter 10909
Gamma-aminobutyric acid receptor subunit epsilon3003
Protein-arginine deiminase type-40101
cytochrome P450 2C9, partial8008
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION0011
Chain H, Fab M82G2, Heavy chain0011
Chain L, Fab M82G2, Light chain0011
Chain H, Fab M82g2, Heavy Chain0011
Chain L, Fab M82g2, Light Chain0011
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Amyloid-beta precursor protein1102
Fatty acid-binding protein, heart0101
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M10101
5-hydroxytryptamine receptor 2C0202
Tryptophan 5-hydroxylase 10101
5-hydroxytryptamine receptor 2A0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
D0101
5-hydroxytryptamine receptor 1A0101
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
Alpha-2A adrenergic receptor0202
Liver carboxylesterase 10102
Sodium-dependent noradrenaline transporter 0819
Sodium-dependent dopamine transporter0202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Gamma-aminobutyric acid receptor subunit beta-30101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0202
5-hydroxytryptamine receptor 60101
Gamma-aminobutyric acid receptor subunit alpha-50101
Sodium-dependent serotonin transporter0415
Sodium-dependent serotonin transporter0304
5-hydroxytryptamine receptor 7 0101
Gamma-aminobutyric acid receptor subunit alpha-30101
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 5B0101
5-hydroxytryptamine receptor 3A0101
Lysosomal Pro-X carboxypeptidase0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
D(2) dopamine receptor0101
Gamma-aminobutyric acid receptor subunit epsilon0101
Sodium-dependent dopamine transporter 0404
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Leukotriene B4 receptor 10101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sodium-dependent dopamine transporter0202
5-hydroxytryptamine receptor 4 0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Sigma non-opioid intracellular receptor 10505
Gamma-aminobutyric acid receptor subunit gamma-30101
5-hydroxytryptamine receptor 3B0101
Leukotriene B4 receptor 20101
Gamma-aminobutyric acid receptor subunit theta0101
Transporter0303
endonuclease IV1001
glp-1 receptor, partial3003
USP1 protein, partial4004
67.9K protein3003
LMP1 [Human herpesvirus 4]0002
chromobox protein homolog 16006
thyroid hormone receptor beta isoform a4004
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
serine/threonine-protein kinase mTOR isoform 12002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Thymidine kinase 2, mitochondrial0101
Thymidine kinase, cytosolic0101
Thymidine kinase0101
Thymidylate synthase0001
Thymidine kinase0101
Deoxycytidine kinase0012
Probable deoxycytidylate deaminase0001
Cytidine deaminase0102
D(1A) dopamine receptor1001
E3 ubiquitin-protein ligase Mdm20101
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
Thymidine kinase0101
Deoxynucleoside kinase0101
Luciferase3003
hypoxia-inducible factor 1 alpha subunit4004
estrogen receptor 2 (ER beta)6006
progesterone receptor8008
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
Lysine-specific demethylase 6B0101
Lysine-specific demethylase 4A0112
Lysine-specific demethylase 5A0101
Flavin reductase (NADPH)0011
Voltage-dependent L-type calcium channel subunit alpha-1C0303
Sodium channel protein type 5 subunit alpha0101
Potassium voltage-gated channel subfamily D member 30101
Chain A, STEROID DELTA-ISOMERASE0011
Steroid Delta-isomerase0011
Vitamin D3 receptor0112
Ileal sodium/bile acid cotransporter0101
G-protein coupled bile acid receptor 10011
Bile acid receptor0011
Cereblon isoform 40202
Insulin-like growth factor-binding protein 50011
Choline O-acetyltransferase 0101
Protein cereblon0202
Chain A, BCL-2-RELATED PROTEIN A10011
apical membrane antigen 1, AMA12002
cytochrome P450 2D64004
unnamed protein product0101
transcriptional regulator ERG isoform 31001
heat shock protein HSP 90-alpha isoform 20002
bcl-2-like protein 11 isoform 10011
Histone deacetylase 30303
Rap guanine nucleotide exchange factor 33003
Chymotrypsinogen A0202
Beta-lactamase0202
Steroid 17-alpha-hydroxylase/17,20 lyase0404
Heme oxygenase 1 0101
ATP-dependent translocase ABCB10303
ATP-dependent translocase ABCB10404
Lanosterol 14-alpha demethylase0134
Aromatase0404
Cytochrome P450 11B1, mitochondrial0303
Cytochrome P450 11B2, mitochondrial0303
ATP-dependent translocase ABCB10303
Heme oxygenase 20101
Malate dehydrogenase, cytoplasmic0202
Histone deacetylase 40303
Cytochrome P450 1440033
Steroid C26-monooxygenase0033
Steroid C26-monooxygenase0033
Mycocyclosin synthase0011
Lanosterol 14-alpha demethylase0011
Lanosterol 14-alpha demethylase0011
Histone deacetylase 10303
Lanosterol 14-alpha demethylase0325
Sterol 14-alpha demethylase0033
Sterol 14-alpha demethylase0224
Histone deacetylase 70303
Histone deacetylase 20303
Polyamine deacetylase HDAC100303
Histone deacetylase 11 0303
14-alpha sterol demethylase 0033
Histone deacetylase 80303
Histone deacetylase 60303
Histone deacetylase 90303
Histone deacetylase 50303
heat shock protein 90, putative0002
likely tRNA 2'-phosphotransferase0101
Skn7p0001
nonstructural protein 12002
heat shock protein 900011
calcineurin A1, putative0011
serine/threonine-protein kinase PLK11001
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
DNA polymerase kappa isoform 12002
Beta-galactosidase0101
Lipopolysaccharide heptosyltransferase 10101
PA-I galactophilic lectin0011
Jacalin0011
Glycogen phosphorylase, muscle form0101
Asialoglycoprotein receptor 10112
histone deacetylase 9 isoform 31001
GALC protein1001
Estrogen receptor beta0102
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0101
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial0202
Cytochrome P450 26A10101
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
3',5'-cyclic-AMP phosphodiesterase 0101
Camphor 5-monooxygenase0001
Phospholipase A2, major isoenzyme0101
Epoxide hydrolase 10001
Aldo-keto reductase family 1 member B10707
Muscarinic acetylcholine receptor M20404
Cytochrome P450 2C11 0101
Steroid 21-hydroxylase0101
Alpha-2A adrenergic receptor0707
Cytochrome P450 2C80203
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Polyunsaturated fatty acid lipoxygenase ALOX150202
Cholesterol side-chain cleavage enzyme, mitochondrial 0101
Indoleamine 2,3-dioxygenase 10101
Cytochrome P450 2A20101
Cytochrome P450 11B1, mitochondrial 0101
Translocator protein0101
Alpha-2B adrenergic receptor0404
Cytochrome P450 7A1 0101
Estrogen receptor0102
Substance-K receptor0202
UDP-glucuronosyltransferase 1A1 0101
Thromboxane-A synthase 0101
Histamine H2 receptor0202
Gonadotropin-releasing hormone receptor0112
Type-1 angiotensin II receptor0101
Delta-type opioid receptor0202
Cytochrome P450 4F20101
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0202
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0101
Sodium/bile acid cotransporter0101
Cytochrome P450 7A10101
Lanosterol 14-alpha demethylase 0202
Integrin beta-32002
Integrin alpha-IIb2002
Solute carrier family 22 member 30101
Amine oxidase [flavin-containing] B0304
Amine oxidase [flavin-containing] B0303
Synaptic vesicular amine transporter0101
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Trace amine-associated receptor 10011
Chain A, Probable serine/threonine-protein kinase pknB0101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
dopamine D1 receptor1001
15-lipoxygenase, partial1001
WRN1001
PPM1D protein3003
Thrombopoietin1001
Smad32002
DNA polymerase III, partial1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
hypothetical protein, conserved1001
nonstructural protein 10101
LANA0001
Parkin1001
pyruvate kinase1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
phospholipase A2, group III0101
cytochrome P450 2D6 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
atrial natriuretic peptide receptor 1 precursor1001
histone-lysine N-methyltransferase NSD2 isoform 10001
huntingtin isoform 21001
mitogen-activated protein kinase 12002
atrial natriuretic peptide receptor 2 precursor1001
flap endonuclease 11001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
ras-related protein Rab-9A1001
protein AF-9 isoform a0001
tyrosine-protein kinase Yes2002
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
DNA polymerase eta isoform 11001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
Vpr1001
DNA repair protein RAD52 homolog isoform a0001
pyruvate kinase PKM isoform b1001
Polyunsaturated fatty acid lipoxygenase ALOX15B3003
Voltage-dependent L-type calcium channel subunit alpha-1F0202
5-hydroxytryptamine receptor 40202
Solute carrier family 22 member 30202
Epidermal growth factor receptor0325
Glycoprotein hormones alpha chain1001
Receptor tyrosine-protein kinase erbB-20213
Tyrosine-protein kinase Fyn0213
Muscarinic acetylcholine receptor M40202
Proto-oncogene tyrosine-protein kinase ROS0101
Ornithine decarboxylase1001
Muscarinic acetylcholine receptor M10202
DNA topoisomerase 2-alpha0113
Angiotensin-converting enzyme0202
DNA topoisomerase 20001
Casein kinase II subunit alpha'0112
5-hydroxytryptamine receptor 2C0202
Multidrug resistance-associated protein 1 0101
Histamine H2 receptor3003
Guanine nucleotide-binding protein G2002
Casein kinase II subunit beta0101
Casein kinase II subunit alpha0101
Inositol monophosphatase 11001
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
DNA topoisomerase 2-beta0012
Tyrosine-protein kinase BTK0325
NEDD8-activating enzyme E1 regulatory subunit0011
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Nuclear receptor subfamily 3 group C member 3 0202
Integrase 0101
Multidrug and toxin extrusion protein 20101
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
Single-stranded DNA cytosine deaminase1001
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30202
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Bone morphogenetic protein receptor type-1B0011
Cell division cycle 7-related protein kinase0011
Serine/threonine-protein kinase PLK40011
ATP-dependent RNA helicase DDX3X0011
Pyridoxal kinase0011
Citron Rho-interacting kinase0011
Serine/threonine-protein kinase Chk10011
Aurora kinase A0011
Cyclin-G-associated kinase0011
Ephrin type-B receptor 60011
Peroxisomal acyl-coenzyme A oxidase 30011
Receptor-interacting serine/threonine-protein kinase 20011
Mitotic checkpoint serine/threonine-protein kinase BUB10011
Testosterone 17-beta-dehydrogenase 30101
Dynamin-like 120 kDa protein, mitochondrial0011
Putative nucleoside diphosphate kinase0011
Tyrosine-protein kinase JAK20202
Rho-associated protein kinase 20011
Serine/threonine-protein kinase ULK10011
Serine/threonine-protein kinase/endoribonuclease IRE10011
Ribosomal protein S6 kinase alpha-50011
U5 small nuclear ribonucleoprotein 200 kDa helicase0011
Ribosomal protein S6 kinase alpha-40011
Serine/threonine-protein kinase 160011
Serine/threonine-protein kinase 100011
Serine/threonine-protein kinase D30011
Structural maintenance of chromosomes protein 20011
Mitogen-activated protein kinase kinase kinase 60011
Mitogen-activated protein kinase kinase kinase kinase 40011
Serine/threonine-protein kinase LATS10011
Serine/threonine-protein kinase PAK 40011
Tyrosine-protein kinase ABL10011
High affinity nerve growth factor receptor0011
Guanine nucleotide-binding protein G(i) subunit alpha-20011
ADP/ATP translocase 20011
Protein kinase C beta type0011
Insulin receptor0011
Tyrosine-protein kinase Lck0112
Glycogen phosphorylase, liver form0011
Tyrosine-protein kinase Fes/Fps0011
Macrophage colony-stimulating factor 1 receptor0101
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0112
Tyrosine-protein kinase Lyn0112
Proto-oncogene tyrosine-protein kinase receptor Ret0112
Insulin-like growth factor 1 receptor0011
Signal recognition particle receptor subunit alpha0011
Cytochrome c1, heme protein, mitochondrial0011
Hepatocyte growth factor receptor0011
Tyrosine-protein kinase HCK0112
Platelet-derived growth factor receptor beta0112
Tyrosine-protein kinase Fgr0101
Serine/threonine-protein kinase A-Raf0011
Glycogen phosphorylase, brain form0011
Breakpoint cluster region protein0011
Serine/threonine-protein kinase pim-10011
Fibroblast growth factor receptor 10011
Cyclin-dependent kinase 40011
ADP/ATP translocase 30011
Inosine-5'-monophosphate dehydrogenase 20011
Proto-oncogene tyrosine-protein kinase Src0112
cAMP-dependent protein kinase type II-alpha regulatory subunit0011
Serine/threonine-protein kinase B-raf0011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0011
Ribosyldihydronicotinamide dehydrogenase [quinone]0011
Tyrosine-protein kinase Fer0011
Protein kinase C alpha type0011
cAMP-dependent protein kinase catalytic subunit alpha0011
General transcription and DNA repair factor IIH helicase subunit XPD0011
Ras-related protein Rab-6A0011
Cytochrome P450 2B60203
Ephrin type-A receptor 10011
Receptor tyrosine-protein kinase erbB-30101
Multifunctional protein ADE20011
Nucleoside diphosphate kinase B0011
cAMP-dependent protein kinase catalytic subunit gamma0011
cAMP-dependent protein kinase catalytic subunit beta0011
Ferrochelatase, mitochondrial0011
Ribosomal protein S6 kinase beta-10011
Tyrosine-protein kinase JAK10213
G1/S-specific cyclin-E10101
Cyclin-dependent kinase 20112
Beta-adrenergic receptor kinase 10011
Probable ATP-dependent RNA helicase DDX60011
Mitogen-activated protein kinase 3 0011
MAP/microtubule affinity-regulating kinase 30011
Mitogen-activated protein kinase 10011
Ephrin type-A receptor 20112
Ephrin type-B receptor 20011
Non-receptor tyrosine-protein kinase TYK20011
Phosphatidylethanolamine-binding protein 10011
Wee1-like protein kinase0011
Heme oxygenase 20011
S-adenosylmethionine synthase isoform type-20011
DnaJ homolog subfamily A member 10011
RAC-alpha serine/threonine-protein kinase0011
RAC-beta serine/threonine-protein kinase0011
Dual specificity protein kinase TTK0011
DNA replication licensing factor MCM40011
Myosin-100011
Dual specificity mitogen-activated protein kinase kinase 20112
Receptor-type tyrosine-protein kinase FLT30213
Bone morphogenetic protein receptor type-1A0011
Activin receptor type-1B0011
TGF-beta receptor type-10011
TGF-beta receptor type-20011
Tyrosine-protein kinase CSK0112
Glycine--tRNA ligase0011
Protein kinase C iota type0011
Exosome RNA helicase MTR40011
Tyrosine-protein kinase Tec0112
Tyrosine-protein kinase TXK0112
Tyrosine-protein kinase ABL20011
Tyrosine-protein kinase FRK0112
G protein-coupled receptor kinase 60011
Tyrosine-protein kinase SYK0112
26S proteasome regulatory subunit 6B0011
Mitogen-activated protein kinase 80011
Mitogen-activated protein kinase 90011
Dual specificity mitogen-activated protein kinase kinase 30011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0011
Casein kinase I isoform delta0011
MAP kinase-activated protein kinase 20011
Elongation factor Tu, mitochondrial0011
Choline-phosphate cytidylyltransferase A0011
Casein kinase I isoform epsilon0011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0011
Dual specificity protein kinase CLK10011
Dual specificity protein kinase CLK20011
Glycogen synthase kinase-3 alpha0011
Glycogen synthase kinase-3 beta0011
Cyclin-dependent kinase 70011
Cyclin-dependent kinase 90011
Ras-related protein Rab-27A0011
Tyrosine-protein kinase Blk0112
Interleukin-1 receptor-associated kinase 10011
Ribosomal protein S6 kinase alpha-30011
Cytoplasmic tyrosine-protein kinase BMX0213
cAMP-dependent protein kinase catalytic subunit PRKX0011
Serine/threonine-protein kinase Nek20011
Serine/threonine-protein kinase Nek30011
Tyrosine-protein kinase JAK30112
Dual specificity mitogen-activated protein kinase kinase 60011
Serine/threonine-protein kinase PLK10011
LIM domain kinase 10011
LIM domain kinase 20011
Mitogen-activated protein kinase 100011
Tyrosine--tRNA ligase, cytoplasmic0011
5'-AMP-activated protein kinase subunit gamma-10012
Ephrin type-B receptor 30011
Ephrin type-A receptor 50011
Ephrin type-B receptor 40011
Ephrin type-A receptor 40011
Adenylate kinase 2, mitochondrial0011
Adenosine kinase0011
Ras-related protein Rab-100011
Actin-related protein 30011
Actin-related protein 20011
GTP-binding nuclear protein Ran0011
Casein kinase I isoform gamma-20011
Cyclin-dependent kinase 30011
Cyclin-dependent kinase 60011
Cyclin-dependent-like kinase 5 0011
Cyclin-dependent kinase 160011
Cyclin-dependent kinase 170011
ATP-dependent 6-phosphofructokinase, platelet type0011
Dual specificity mitogen-activated protein kinase kinase 10011
Protein kinase C theta type0011
Activin receptor type-10011
Macrophage-stimulating protein receptor0011
Focal adhesion kinase 10011
Protein kinase C delta type0011
Activated CDC42 kinase 10011
Epithelial discoidin domain-containing receptor 10011
Tyrosine-protein kinase ITK/TSK0112
Mitogen-activated protein kinase kinase kinase kinase 20011
Tyrosine-protein kinase Mer0011
Serine/threonine-protein kinase 40011
5'-AMP-activated protein kinase catalytic subunit alpha-10012
Dual specificity mitogen-activated protein kinase kinase 50011
Mitogen-activated protein kinase 70011
Serine/threonine-protein kinase PAK 20011
Serine/threonine-protein kinase 30011
Mitogen-activated protein kinase kinase kinase 10011
Integrin-linked protein kinase0011
Rho-associated protein kinase 10011
Non-receptor tyrosine-protein kinase TNK10011
Calcium/calmodulin-dependent protein kinase type II subunit gamma0011
Calcium/calmodulin-dependent protein kinase type II subunit delta0011
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0011
Activin receptor type-2B0011
Bone morphogenetic protein receptor type-20011
Protein-tyrosine kinase 60112
cGMP-dependent protein kinase 1 0011
Cyclin-dependent kinase 130011
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0011
Protein-tyrosine kinase 2-beta0011
Maternal embryonic leucine zipper kinase0011
Structural maintenance of chromosomes protein 1A0011
Chromodomain-helicase-DNA-binding protein 40011
Serine/threonine-protein kinase 380011
Receptor tyrosine-protein kinase erbB-40112
Ephrin type-A receptor 70011
Delta(24)-sterol reductase0011
Ribosomal protein S6 kinase alpha-10112
Myosin light chain kinase, smooth muscle0011
Mitogen-activated protein kinase 110011
Serine/threonine-protein kinase STK110011
Serine/threonine-protein kinase N10011
Serine/threonine-protein kinase N20011
Mitogen-activated protein kinase 140011
Calcium/calmodulin-dependent protein kinase type IV0011
Mitogen-activated protein kinase kinase kinase 110011
MAP kinase-activated protein kinase 30011
Discoidin domain-containing receptor 20011
AP2-associated protein kinase 10011
Myosin light chain kinase 30011
Putative heat shock protein HSP 90-beta 20011
Rab-like protein 30011
Sigma intracellular receptor 20202
Serine/threonine-protein kinase MRCK alpha0011
Serine/threonine-protein kinase MRCK gamma0011
Acyl-CoA dehydrogenase family member 100011
Serine/threonine-protein kinase ULK30011
Uncharacterized protein FLJ452520011
Acyl-CoA dehydrogenase family member 110011
Serine/threonine-protein kinase/endoribonuclease IRE20011
Serine/threonine-protein kinase MARK20011
ATP-dependent RNA helicase DHX300011
Serine/threonine-protein kinase TAO10011
STE20-related kinase adapter protein alpha0011
Myosin-140011
AarF domain-containing protein kinase 10011
ATP-dependent RNA helicase DDX420011
Mitogen-activated protein kinase kinase kinase kinase 30011
MAP kinase-activated protein kinase 50011
Misshapen-like kinase 10011
Atypical kinase COQ8A, mitochondrial0011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0011
Mitogen-activated protein kinase 150011
Serine/threonine-protein kinase Nek90011
Serine/threonine-protein kinase Nek70011
ATP-dependent RNA helicase DDX10011
Nuclear receptor subfamily 4 group A member 30101
Mitogen-activated protein kinase kinase kinase kinase 10011
MAP/microtubule affinity-regulating kinase 40011
Calcium/calmodulin-dependent protein kinase type 1G0011
Serine/threonine-protein kinase Nek10011
PAS domain-containing serine/threonine-protein kinase0011
Calcium/calmodulin-dependent protein kinase kinase 20011
EKC/KEOPS complex subunit TP53RK0011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0011
Mitogen-activated protein kinase kinase kinase 50011
Mitogen-activated protein kinase kinase kinase 30011
Eukaryotic translation initiation factor 2-alpha kinase 10011
Peroxiredoxin-like 2A0101
Nucleolar GTP-binding protein 10011
Serine/threonine-protein kinase D20011
NUAK family SNF1-like kinase 20011
RNA cytidine acetyltransferase0011
Serine/threonine-protein kinase SIK20011
STE20-like serine/threonine-protein kinase 0011
Serine/threonine-protein kinase TAO30011
dCTP pyrophosphatase 10011
Dual specificity protein kinase CLK40011
Platelet glycoprotein VI0101
Casein kinase I isoform gamma-10011
Serine/threonine-protein kinase PAK 60011
Phenylalanine--tRNA ligase beta subunit0011
BMP-2-inducible protein kinase0011
Obg-like ATPase 10011
Midasin0011
Interleukin-1 receptor-associated kinase 40011
Mitogen-activated protein kinase kinase kinase 200011
Cyclin-dependent kinase 120011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130011
Serine/threonine-protein kinase 260011
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0011
Serine/threonine-protein kinase NLK0011
5'-AMP-activated protein kinase subunit gamma-20012
Serine/threonine-protein kinase TBK10011
Septin-90011
Ribosomal protein S6 kinase alpha-60011
TRAF2 and NCK-interacting protein kinase0011
Serine/threonine-protein kinase TAO20011
Serine/threonine-protein kinase ICK0011
RAC-gamma serine/threonine-protein kinase0011
Serine/threonine-protein kinase SIK30011
Mitogen-activated protein kinase kinase kinase 20011
Thyroid hormone receptor-associated protein 30011
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0011
Mitogen-activated protein kinase kinase kinase kinase 50011
Receptor-interacting serine/threonine-protein kinase 30011
Serine/threonine-protein kinase MRCK beta0011
Interleukin-1 receptor-associated kinase 30011
Serine/threonine-protein kinase 240011
Casein kinase I isoform gamma-30011
Mitogen-activated protein kinase kinase kinase 40011
Sterol 14-alpha-demethylase0022
caspase 7, apoptosis-related cysteine protease2002
caspase-32002
14-alpha sterol demethylase 0022
14-alpha sterol demethylase 0022
luciferase0001
nuclear receptor subfamily 1, group I, member 21001
Fatty acid-binding protein, liver0101
Estrogen receptor0202
Glucocorticoid receptor04211
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0101
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
Histamine H1 receptor0011
Prostaglandin G/H synthase 20202
Nociceptin receptor0011
Cytochrome P450 2J20101
Estrogen receptor beta0202
pregnane X receptor3003
aldehyde dehydrogenase 1 family, member A14004
nuclear receptor ROR-gamma isoform 13003
Chain A, Beta-lactamase2002
Chain A, 2-oxoglutarate Oxygenase2002
chaperonin-containing TCP-1 beta subunit homolog1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
Solute carrier family 22 member 60101
Polyphenol oxidase 20102
Carbonic anhydrase 120101
5'-AMP-activated protein kinase subunit beta-20001
Carbonic anhydrase 10202
Carbonic anhydrase 20202
Albumin0123
Polymerase acidic protein0011
Carbonic anhydrase 30101
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Tyrosine-protein phosphatase non-receptor type 10103
Acetylcholinesterase0202
Carbonic anhydrase 40101
Prostaglandin G/H synthase 10101
Carbonic anhydrase 60101
Cystathionine gamma-lyase0101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70101
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
Carbonic anhydrase 90101
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Nicotinate phosphoribosyltransferase0101
Solute carrier family 22 member 200101
Solute carrier family 22 member 80101
Solute carrier family 22 member 60101
Ubiquitin-like domain-containing CTD phosphatase 10101
Carbonic anhydrase 150101
Carbonic anhydrase 130101
5'-AMP-activated protein kinase subunit gamma-30001
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
5'-AMP-activated protein kinase subunit beta-10001
Acetylcholinesterase0101
Cytochrome P450 2B10101
Cholinesterase0101
Amine oxidase [flavin-containing] A 0203
Amine oxidase [flavin-containing] A0202
Amine oxidase [flavin-containing] A 0202
Adenosine receptor A10101
Amine oxidase [flavin-containing] B0213
Type-1 angiotensin II receptor0101
Alpha-synuclein0101
C-X-C chemokine receptor type 30101
Amine oxidase [flavin-containing] A0001
Amine oxidase [flavin-containing] B0001
cystic fibrosis transmembrane conductance regulator0101
potassium voltage-gated channel subfamily H member 2 isoform d2002
C-8 sterol isomerase0101
Squalene monooxygenase 0101
Squalene monooxygenase0202
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0101
lethal factor (plasmid)1001
Urease subunit alpha0101
Urease subunit beta0101
Olfactory receptor 51E20011
Cocaine esterase0101
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 2B70102
UDP-glucuronosyltransferase 1-60001
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Sigma non-opioid intracellular receptor 10101
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
60 kDa heat shock protein, mitochondrial0101
Alpha-1B adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Alpha-1A adrenergic receptor0101
10 kDa heat shock protein, mitochondrial0101
D-alanyl-D-alanine dipeptidase0101
Thiosulfate sulfurtransferase0101
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Cholesterol side-chain cleavage enzyme, mitochondrial 0011
Cholesterol 24-hydroxylase0213
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Albumin0011
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]