Page last updated: 2024-09-27

Central Nervous System Cysts

Congenital or acquired cysts of the brain, spinal cord, or meninges which may remain stable in size or undergo progressive enlargement.

Synonyms(8)

Synonym
Rathke's Cleft Cyst
CNS Cysts
Central Nervous System Cysts
Rathke's Cleft Cysts
Suprasellar Cyst
Cysts, Central Nervous System
Rathke Cleft Cyst
Rathke Cleft Cysts

Research Excerpts

Overview

ExcerptReference
"Rathke cleft cysts are commonly found on autopsy but are seldom symptomatic."( Hsu, HY; Piva, A; Sadun, AA, 2004)
"Microscopic Rathke cleft cysts are a common incidental autopsy finding, but some Rathke cleft cysts can become sufficiently large to cause visual impairment, hypothalamic-pituitary dysfunction, and headaches."( Aho, CJ; Couldwell, WT; Liu, C; Weiss, MH; Zelman, V, 2005)

Context

ExcerptReference
"Rathke cleft cysts have been known to recur after primary surgery; however, this is the first report of a single cyst recurring three times despite conventional surgical treatment."( Hsu, HY; Piva, A; Sadun, AA, 2004)

Treatment

ExcerptReference
"The authors report on a woman with Rathke cleft cyst that recurred three times after the initial treatment; the lesion was treated with alcohol cauterization on the final recurrence with devastating complications."( Hsu, HY; Piva, A; Sadun, AA, 2004)
"To clarify the outcome of all cases of Rathke's cleft cysts (RCC) treated surgically and followed up in Oxford during a long-term period."( Ansorge, O; Byrne, JV; Cudlip, S; Karavitaki, N; Plaha, P; Stavrinides, V; Trifanescu, R; Wass, JA, 2011)

Research

Studies (115)

TimeframeStudies, This Condition (%)All Conditions %
pre-19904 (3.48)23.3326
1990's0 (0.00)12.5806
2000's46 (40.00)18.1394
2010's52 (45.22)28.8240
2020's13 (11.30)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminolevulinic acid0low20
carnitine0low20
choline0low10
salicylic acid0low10
creatine0low20
lactic acid0low10
inositol0low10
melatonin0low10
albendazole0low40
aspirin0low10
verapamil0low10
carmustine0low30
metformin0low10
metoclopramide0low10
metronidazole0low10
nimodipine0low10
pioglitazone0low10
piracetam0low10
praziquantel0low10
risperidone0low10
sumatriptan0low10
thalidomide0low10
thiotepa0low10
ticlopidine0low10
prednisolone0low20
thyroxine0low20
serine0low20
aspartic acid0low40
levodopa0low10
leucine0low20
methionine0low10
phencyclidine0low10
pyrazines0low10
vancomycin0low20
mannose0low10
rhenium0low20
gadolinium0low20
amoxicillin0low10
s-adenosylmethionine0low10
etoposide0low10
cabergoline0low30
clopidogrel0low10
n-acetylaspartic acid0low40
triazoles0low10
fluorodeoxyglucose f180low10
fibrinogen0low10
cobalt0low10
amotosalen0low10
biotin0low10
cortisone0low30
carboplatin0low20
riboflavin0low10
bromochloroacetic acid0low90
curcumin0low10
amphotericin b0low10
phenylephrine hydrochloride0low80
levetiracetam0low10
deamino arginine vasopressin0low50
latanoprost0low10
cysteine0low10
gadolinium dtpa0low40
ergoline0low30
pasireotide0low10
sitagliptin phosphate0low10
indocyanine green0low10
pituitrin0low10
carbon-11 methionine0low10
cosyntropin0medium11
glucagon0medium11
ro13-99040low20
sodium ethylxanthate0low10
olanzapine0low10
eye0low10
technetium tc 99m bicisate0low10
phosphorus radioisotopes0medium31

Protein Targets (820)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit8008
RAR-related orphan receptor gamma170017
GLI family zinc finger 3140014
AR protein230023
aldehyde dehydrogenase 1 family, member A1160016
retinoic acid nuclear receptor alpha variant 1150015
retinoid X nuclear receptor alpha120012
estrogen nuclear receptor alpha240024
peroxisome proliferator-activated receptor delta100010
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
activating transcription factor 65005
v-jun sarcoma virus 17 oncogene homolog (avian)140014
Histone H2A.x7007
thyroid hormone receptor beta isoform a7007
heat shock protein beta-19009
nuclear factor erythroid 2-related factor 2 isoform 1150015
lamin isoform A-delta10190019
Voltage-dependent calcium channel gamma-2 subunit6006
Glutamate receptor 26006
Chain A, Beta-lactamase7007
Luciferase6006
glp-1 receptor, partial6006
ATAD5 protein, partial7007
Fumarate hydratase1001
TDP1 protein200020
caspase 7, apoptosis-related cysteine protease4004
nuclear receptor subfamily 1, group I, member 3130013
progesterone receptor110011
glucocorticoid receptor [Homo sapiens]160016
estrogen-related nuclear receptor alpha150015
farnesoid X nuclear receptor9009
pregnane X nuclear receptor160016
polyprotein1001
67.9K protein3003
peroxisome proliferator activated receptor gamma130013
vitamin D (1,25- dihydroxyvitamin D3) receptor100010
caspase-34004
IDH14004
euchromatic histone-lysine N-methyltransferase 2210021
aryl hydrocarbon receptor9009
nuclear receptor subfamily 1, group I, member 23003
cellular tumor antigen p53 isoform a4004
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 17007
chromobox protein homolog 1140014
nuclear factor erythroid 2-related factor 2 isoform 24004
transcriptional regulator ERG isoform 35005
thyroid hormone receptor beta isoform 2120012
histone deacetylase 9 isoform 31001
mitogen-activated protein kinase 17007
urokinase-type plasminogen activator precursor4004
plasminogen precursor4004
urokinase plasminogen activator surface receptor precursor4004
geminin190019
Vif0001
peripheral myelin protein 227007
survival motor neuron protein isoform d6006
muscleblind-like protein 1 isoform 14004
DNA dC->dU-editing enzyme APOBEC-3G isoform 12002
neuropeptide S receptor isoform A4004
ATP-binding cassette sub-family C member 3023023
Multidrug resistance-associated protein 4023023
Bile salt export pump028028
Interferon beta9009
Cellular tumor antigen p53160016
Integrin beta-33104
Integrin alpha-IIb3104
Methionine aminopeptidase0101
Fatty-acid amide hydrolase 10101
Inositol monophosphatase 13003
Canalicular multispecific organic anion transporter 1023024
ATPase family AAA domain-containing protein 54004
Ataxin-25005
bromodomain adjacent to zinc finger domain 2B3003
Gamma-aminobutyric acid receptor subunit rho-10101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10303
Glutamate receptor 40101
Solute carrier family 15 member 10202
Solute carrier family 15 member 20202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE110011
Chain A, 2-oxoglutarate Oxygenase9009
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
apical membrane antigen 1, AMA15005
Beta-lactamase 0001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 16006
DNA polymerase eta isoform 13003
DNA polymerase iota isoform a (long)9009
DNA polymerase kappa isoform 1100010
Bile salt export pump0707
Beta-lactamase SHV-10001
Beta-lactamase SHV-10001
Cytochrome P450 2C9 0707
Beta-lactamase0001
Kappa-type opioid receptor0102
Cytochrome P450 2J20505
B2 metallo-beta-lactamase 0001
Solute carrier family 15 member 20101
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Chain A, HADH2 protein7007
Chain B, HADH2 protein7007
Chain A, Cruzipain3003
interleukin 84004
phosphopantetheinyl transferase7007
GLS protein9009
tumor necrosis factor2002
vitamin D3 receptor isoform VDRA8008
Cytochrome P450 1A20202
Cytochrome P450 3A40505
Cytochrome P450 2D60606
Cytochrome P450 2C190505
Nuclear receptor ROR-gamma5005
Potassium voltage-gated channel subfamily H member 20606
Aurora kinase B0101
Broad substrate specificity ATP-binding cassette transporter ABCG20415
Chain A, TYROSYL-DNA PHOSPHODIESTERASE8008
Chain A, Ferritin light chain5005
arylsulfatase A8008
Bloom syndrome protein isoform 1100010
cytochrome P450 2C19 precursor4004
lethal factor (plasmid)5005
Metabotropic glutamate receptor 60011
Excitatory amino acid transporter 40101
Glutamate transporter homolog0011
Carbonic anhydrase 10406
Carbonic anhydrase 20507
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase0101
5-hydroxytryptamine receptor 1D0215
Glutamate receptor ionotropic, NMDA 1 0305
Excitatory amino acid transporter 10101
Excitatory amino acid transporter 20101
Excitatory amino acid transporter 30101
Glutamate receptor ionotropic, NMDA 2A 0305
Glutamate receptor ionotropic, NMDA 2B0305
Glutamate receptor ionotropic, NMDA 2C0306
Metabotropic glutamate receptor 10011
Metabotropic glutamate receptor 20011
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0305
Glutamate receptor ionotropic, NMDA 3B0305
Carbonic anhydrase 40001
Glutamate receptor ionotropic, NMDA 3A0305
Chain A, Phospholipase A2 isoform 30011
GTP-binding protein (rab7)0011
ras protein, partial0011
thioredoxin reductase150015
thyroid stimulating hormone receptor6006
hypothetical protein, conserved1001
cytochrome P450 family 3 subfamily A polypeptide 4140014
EWS/FLI fusion protein170018
cytochrome P450 2D6130013
glucocerebrosidase3003
Rac1 protein0011
cell division cycle 42 (GTP binding protein, 25kDa), partial0011
muscarinic acetylcholine receptor M1100010
Prostaglandin-H2 D-isomerase0101
Solute carrier family 22 member 60202
Prostaglandin G/H synthase 1 0101
Prostaglandin G/H synthase 2 0101
Epidermal growth factor receptor0202
Fatty acid-binding protein, liver0202
Myeloperoxidase0303
Prostaglandin G/H synthase 10303
Seed linoleate 13S-lipoxygenase-10101
Glutathione hydrolase 1 proenzyme0101
Prostaglandin G/H synthase 10303
Adenosine receptor A10203
Adenosine receptor A2a0203
Substance-P receptor0101
Prostaglandin G/H synthase 20505
Urotensin-2 receptor0101
4-aminobutyrate aminotransferase, mitochondrial0101
Ras-related protein Rab-2A0011
Gamma-aminobutyric acid receptor subunit alpha-18109
Prostaglandin G/H synthase 20202
Rho-associated protein kinase 20101
Nicotinate phosphoribosyltransferase0202
Solute carrier family 22 member 200303
Solute carrier family 22 member 60303
Sigma non-opioid intracellular receptor 10314
Sigma non-opioid intracellular receptor 10213
Chain A, Avidin0011
Chain A, Protein (streptavidin)0011
Chain B, Protein (streptavidin)0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin0011
Chain D, Streptavidin0011
Chain A, Streptavidin Complex With Biotin0011
Chain D, Circularly Permuted Core-streptavidin E51/a460011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Core-streptavidin0011
Chain D, Core-streptavidin0011
Chain A, Avidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, Streptavidin0011
Chain B, Streptavidin0011
Chain A, JmjC domain-containing histone demethylation protein 3A5005
nonstructural protein 10101
green fluorescent protein, partial0101
insulin-degrading enzyme isoform 10011
Streptavidin0011
Receptor-type tyrosine-protein phosphatase beta0001
thyroid stimulating hormone receptor110011
acetylcholinesterase9009
5-hydroxytryptamine receptor 2B09110
Spike glycoprotein9009
Histamine H3 receptor0303
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
estrogen receptor 2 (ER beta)6006
G6006
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
histone acetyltransferase KAT2A isoform 15005
HLA class I histocompatibility antigen, B alpha chain 6006
Inositol hexakisphosphate kinase 16006
cytochrome P450 2C9, partial6006
ATP-dependent phosphofructokinase8008
endonuclease IV3003
peripheral myelin protein 22 isoform 15005
huntingtin isoform 23003
nuclear receptor ROR-gamma isoform 13003
Glutathione reductase, mitochondrial0101
Alpha-synuclein2114
Glutathione reductase0101
Solute carrier family 22 member 50001
Solute carrier family 22 member 50001
Solute carrier family 22 member 160001
Solute carrier family 22 member 210001
Solute carrier family 22 member 50001
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein0011
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Glycine betaine/carnitine/choline-binding protein0011
Chain A, Choline-binding protein0011
Solute carrier family 22 member 10102
Solute carrier family 22 member 20203
Solute carrier family 22 member 1 0406
Solute carrier family 22 member 20101
Neuronal acetylcholine receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit alpha-41102
Neuronal acetylcholine receptor subunit alpha-20101
Neuronal acetylcholine receptor subunit beta-21102
Neuronal acetylcholine receptor subunit beta-30101
Neuronal acetylcholine receptor subunit beta-40101
Neuronal acetylcholine receptor subunit alpha-50101
Acetylcholinesterase0505
Sodium- and chloride-dependent creatine transporter 10101
Choline O-acetyltransferase 0001
Neuronal acetylcholine receptor subunit alpha-60101
Neuronal acetylcholine receptor subunit alpha-90101
Neuronal acetylcholine receptor subunit alpha-70101
Solute carrier family 22 member 10103
High affinity choline transporter 10101
Neuronal acetylcholine receptor subunit alpha-100101
Solute carrier family 22 member 20102
nonstructural protein 12002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
Cytochrome P450 2C80303
Cytochrome P450 2B60505
Liver carboxylesterase 10001
Sodium-dependent serotonin transporter0707
Rap guanine nucleotide exchange factor 43003
P2Y purinoceptor 120101
dopamine D1 receptor2002
pregnane X receptor2002
regulator of G-protein signaling 47007
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
atrial natriuretic peptide receptor 1 precursor2002
flap endonuclease 14004
cytochrome P450 3A4 isoform 18008
M-phase phosphoprotein 86006
Gamma-aminobutyric acid receptor subunit pi8008
Glucocorticoid receptor04110
Sex hormone-binding globulin0011
Glycine receptor subunit alpha-10404
Corticosteroid-binding globulin0202
Gamma-aminobutyric acid receptor subunit beta-18008
Gamma-aminobutyric acid receptor subunit delta8008
Gamma-aminobutyric acid receptor subunit gamma-28008
Gamma-aminobutyric acid receptor subunit alpha-58008
Gamma-aminobutyric acid receptor subunit alpha-38008
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Gamma-aminobutyric acid receptor subunit gamma-18008
Gamma-aminobutyric acid receptor subunit alpha-28008
Glycine receptor subunit alpha-30404
Gamma-aminobutyric acid receptor subunit alpha-48008
Gamma-aminobutyric acid receptor subunit gamma-38008
Gamma-aminobutyric acid receptor subunit alpha-68008
Gamma-aminobutyric acid receptor subunit beta-38008
Gamma-aminobutyric acid receptor subunit beta-28008
Potassium voltage-gated channel subfamily A member 10011
TAR DNA-binding protein 435005
GABA theta subunit8008
Multidrug and toxin extrusion protein 10404
Gamma-aminobutyric acid receptor subunit epsilon8008
Sodium- and chloride-dependent creatine transporter 10101
Proton-coupled amino acid transporter 10304
Chain A, Breast cancer type 1 susceptibility protein2002
Nrf21001
15-lipoxygenase, partial3003
SMAD family member 24004
USP1 protein, partial3003
SMAD family member 34004
Microtubule-associated protein tau2002
alkaline phosphatase, intestinal0101
thioredoxin glutathione reductase1001
Smad32002
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
PINK11001
Parkin2002
toll-like receptor 90101
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
TPA: protein transporter TIM100101
thyrotropin-releasing hormone receptor2002
lysosomal alpha-glucosidase preproprotein4004
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0101
hemoglobin subunit beta2002
polyunsaturated fatty acid lipoxygenase ALOX121001
perilipin-50101
intestinal alkaline phosphatase precursor0101
perilipin-10101
potassium voltage-gated channel subfamily H member 2 isoform d5005
importin subunit beta-1 isoform 12002
pyruvate kinase PKM isoform a1001
DNA polymerase beta1001
nuclear factor NF-kappa-B p105 subunit isoform 12002
snurportin-12002
tumor susceptibility gene 101 protein1001
GTP-binding nuclear protein Ran isoform 11001
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a0101
alkaline phosphatase, germ cell type preproprotein0101
caspase-1 isoform alpha precursor2002
hypothetical protein SA14220101
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Prostaglandin E synthase0101
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Histone deacetylase 30101
Acetylcholinesterase0202
Lysine-specific histone demethylase 1A0101
D-amino-acid oxidase0101
Phospholipase A20101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10202
Amyloid-beta precursor protein0203
Neuronal proto-oncogene tyrosine-protein kinase Src 0101
Cholinesterase0202
Heme oxygenase 1 0101
Glutathione S-transferase P0101
Polyunsaturated fatty acid 5-lipoxygenase0101
60 kDa chaperonin0202
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Microtubule-associated protein tau0102
60 kDa heat shock protein, mitochondrial0303
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 0101
Tissue factor0101
Tyrosinase0202
Aminopeptidase N0101
Aminopeptidase N0101
Alpha-1B adrenergic receptor0606
Sarcoplasmic/endoplasmic reticulum calcium ATPase 20202
Glycogen synthase kinase-3 beta0101
Amine oxidase [flavin-containing] A0303
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Heme oxygenase 20101
Alpha-1D adrenergic receptor0606
Amine oxidase [flavin-containing] B0404
Voltage-dependent L-type calcium channel subunit alpha-1D0101
Proteasome subunit beta type-50101
17-beta-hydroxysteroid dehydrogenase type 20101
Alpha-1A adrenergic receptor0707
Histamine H2 receptor2002
Glycogen synthase kinase-3 beta0101
Caspase-72002
Histone deacetylase 40101
Beta-secretase 10101
10 kDa heat shock protein, mitochondrial0303
Guanine nucleotide-binding protein G2002
Cholinesterase0202
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
Serine/threonine-protein kinase PAK 10101
Histone deacetylase 10202
5-hydroxytryptamine receptor 40011
Sodium/bile acid cotransporter0011
Nuclear factor erythroid 2-related factor 20012
Thiosulfate sulfurtransferase0303
Thioredoxin reductase 1, cytoplasmic0101
60 kDa chaperonin 0303
10 kDa chaperonin 0303
Thioredoxin reductase 30101
Sortase A0101
Histone deacetylase 70101
Histone deacetylase 20202
CREB-binding protein0101
Sarcoplasmic/endoplasmic reticulum calcium ATPase 30202
Cysteine protease 0101
Polyamine deacetylase HDAC100101
Histone deacetylase 11 0101
NACHT, LRR and PYD domains-containing protein 3 0101
Histone deacetylase 80202
Thioredoxin reductase 2, mitochondrial0101
CDGSH iron-sulfur domain-containing protein 10404
Histone deacetylase 60101
Histone deacetylase 90101
Histone deacetylase 50101
Lymphocyte antigen 960011
Beta lactamase (plasmid)0101
Vasopressin V2 receptor0112
Oxytocin receptor0011
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Translocator protein0101
Vasopressin V2 receptor 0112
LMP1 [Human herpesvirus 4]0001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Prothrombin0001
Regulatory protein E20011
ATP-dependent translocase ABCB10202
ATP-dependent translocase ABCB104115
DNA topoisomerase 10102
DNA topoisomerase 2-alpha0117
Polyunsaturated fatty acid lipoxygenase ALOX150303
DNA topoisomerase 20001
ATP-dependent translocase ABCB10203
UDP-glucuronosyltransferase 1A1 0102
Serum paraoxonase/arylesterase 10101
Caspase-30101
DNA topoisomerase 2-alpha 0001
DNA topoisomerase 2-beta0118
Tubulin beta-2B chain0101
Integrase 0101
Similar to alpha-tubulin isoform 1 0101
Similar to alpha-tubulin isoform 1 0101
Solute carrier organic anion transporter family member 1B30202
Chain B, Pulmonary surfactant-associated protein D0101
Chain A, Pulmonary surfactant-associated protein D0101
Sodium/myo-inositol cotransporter 20101
beta-2 adrenergic receptor2002
Solute carrier organic anion transporter family member 2A10101
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Chain A, Leucine Aminopeptidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Intestinal-type alkaline phosphatase0101
Large neutral amino acids transporter small subunit 10303
Phospholipase A-2-activating protein0101
Gonadotropin-releasing hormone receptor0101
Gonadotropin-releasing hormone receptor0202
chaperonin-containing TCP-1 beta subunit homolog2002
Synaptic vesicle glycoprotein 2A0202
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
pyruvate kinase1001
hexokinase-4 isoform 11001
glucokinase regulatory protein1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a3003
Polyphenol oxidase 20103
Carbonic anhydrase 120102
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Carbonic anhydrase 30102
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase0001
Carbonic anhydrase 70102
Carbonic anhydrase0001
SLC16A10 protein0001
Carbonic anhydrase 90102
Carbonic anhydrase 0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150102
Carbonic anhydrase 130102
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
phosphoglycerate kinase1001
Alpha-mannosidase 2C10101
Fucose-binding lectin PA-IIL0101
CD209 antigen0101
ClpP1001
cytochrome P450 2D6 isoform 14004
ras-related protein Rab-9A1001
Cytochrome P450 1A10101
Cytochrome P450 1A2 0101
Cytochrome P450 2C11 0101
Aromatase0101
Ribosyldihydronicotinamide dehydrogenase [quinone]0202
Metabotropic glutamate receptor 10101
Acetylcholinesterase 0101
Mu-type opioid receptor0202
Nociceptin receptor0101
Melatonin receptor type 1A0213
Melatonin receptor type 1C0011
Melatonin receptor type 1A0112
Melatonin receptor type 1B0213
Melatonin receptor type 1C0112
Melatonin receptor type 1B0112
Cytochrome P450 1B10101
Palmitoleoyl-protein carboxylesterase NOTUM0101
Carboxylic ester hydrolase 0101
Dihydrofolate reductase0101
Dipeptidyl peptidase 40101
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
5-hydroxytryptamine receptor 3E0213
D(1A) dopamine receptor1001
5-hydroxytryptamine receptor 40808
5-hydroxytryptamine receptor 3B0213
Albumin0022
5-hydroxytryptamine receptor 2C0606
Alpha-2A adrenergic receptor011011
D(2) dopamine receptor0707
5-hydroxytryptamine receptor 2A0606
D0303
D(3) dopamine receptor0303
5-hydroxytryptamine receptor 1A0819
Alpha-2B adrenergic receptor0404
D(2) dopamine receptor0101
Alpha-2C adrenergic receptor0404
Alpha-2A adrenergic receptor0404
5-hydroxytryptamine receptor 3A0101
D(1B) dopamine receptor0101
5-hydroxytryptamine receptor 2A010010
5-hydroxytryptamine receptor 2C0909
5-hydroxytryptamine receptor 1B0707
5-hydroxytryptamine receptor 1D0213
D(4) dopamine receptor0202
5-hydroxytryptamine receptor 1F0101
5-hydroxytryptamine receptor 2B0505
D(3) dopamine receptor0808
5-hydroxytryptamine receptor 3A0303
5-hydroxytryptamine receptor 3A0213
5-hydroxytryptamine receptor 70202
6-phosphogluconate dehydrogenase, decarboxylating0101
D(2) dopamine receptor0808
Lactoperoxidase0101
5-hydroxytryptamine receptor 4 0102
5-hydroxytryptamine receptor 3D0213
5-hydroxytryptamine receptor 3C0213
5-hydroxytryptamine receptor 3B0101
5-hydroxytryptamine receptor 3B0303
Thioredoxin reductase 0101
Flavodoxin0001
Voltage-dependent L-type calcium channel subunit alpha-1F0415
Voltage-dependent L-type calcium channel subunit alpha-1D 0415
Voltage-dependent L-type calcium channel subunit alpha-1S0415
Voltage-dependent L-type calcium channel subunit alpha-1C0415
Lanosterol 14-alpha demethylase0101
Voltage-dependent L-type calcium channel subunit beta-40101
Voltage-dependent P/Q-type calcium channel subunit alpha-1A0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Voltage-dependent T-type calcium channel subunit alpha-1G0101
Voltage-dependent calcium channel gamma-3 subunit0101
Nuclear receptor subfamily 1 group I member 20022
Voltage-dependent T-type calcium channel subunit alpha-1H0101
Adenosine receptor A30101
Cannabinoid receptor 10202
Voltage-dependent L-type calcium channel subunit beta-30101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Voltage-dependent calcium channel gamma-7 subunit0101
Voltage-dependent N-type calcium channel subunit alpha-1B0101
Voltage-dependent L-type calcium channel subunit beta-10101
Voltage-dependent calcium channel gamma-1 subunit0101
Voltage-dependent L-type calcium channel subunit beta-20101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0202
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Voltage-dependent R-type calcium channel subunit alpha-1E0101
Voltage-dependent calcium channel subunit alpha-2/delta-40101
Transient receptor potential cation channel subfamily A member 10011
Voltage-dependent calcium channel subunit alpha-2/delta-30101
Voltage-dependent calcium channel gamma-8 subunit0101
Bile acid receptor0202
Voltage-dependent calcium channel gamma-6 subunit0101
Voltage-dependent calcium channel subunit alpha-2/delta-20101
Voltage-dependent T-type calcium channel subunit alpha-1I0101
Voltage-dependent calcium channel gamma-4 subunit0101
Voltage-dependent calcium channel gamma-5 subunit0101
Voltage-dependent calcium channel gamma-2 subunit0101
FAD-linked sulfhydryl oxidase ALR0001
Muscarinic acetylcholine receptor M20314
Muscarinic acetylcholine receptor M40303
5-hydroxytryptamine receptor 1A0448
Muscarinic acetylcholine receptor M50404
Muscarinic acetylcholine receptor M10336
Glucose-6-phosphate 1-dehydrogenase0101
Angiotensin-converting enzyme0303
Alpha-2B adrenergic receptor0606
Alpha-2C adrenergic receptor0606
Muscarinic acetylcholine receptor M30404
D(1A) dopamine receptor0404
D(4) dopamine receptor0303
UDP-glucuronosyltransferase 1A40001
Sodium-dependent noradrenaline transporter 0101
Alpha-1D adrenergic receptor0404
Histamine H1 receptor0213
5-hydroxytryptamine receptor 70303
Alpha-1A adrenergic receptor0404
Histamine H1 receptor0415
Alpha-1B adrenergic receptor0202
5-hydroxytryptamine receptor 60303
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0202
Disintegrin and metalloproteinase domain-containing protein 172002
Sigma non-opioid intracellular receptor 10101
Transporter0202
Nuclear receptor subfamily 3 group C member 3 0303
Transporter0303
interferon gamma precursor0001
Somatostatin receptor type 10101
Somatostatin receptor type 20101
Somatostatin receptor type 40101
Somatostatin receptor type 30101
Somatostatin receptor type 50101
Chain A, Immunoglobulin0011
Chain B, Immunoglobulin0011
Glutamate receptor ionotropic, NMDA 2D0101
Glutamate receptor ionotropic, NMDA 3B0101
Muscarinic acetylcholine receptor M10225
Muscarinic acetylcholine receptor M30225
Muscarinic acetylcholine receptor M40225
Muscarinic acetylcholine receptor M50225
Muscarinic acetylcholine receptor M20225
Muscarinic acetylcholine receptor M10023
Sodium-dependent serotonin transporter0202
Muscarinic acetylcholine receptor M40012
Delta-type opioid receptor0102
Kappa-type opioid receptor0001
Lysosomal Pro-X carboxypeptidase0101
Mu-type opioid receptor0001
Cholinesterase0101
Glutamate receptor ionotropic, NMDA 10202
Glutamate receptor ionotropic, NMDA 2A0202
Glutamate receptor ionotropic, NMDA 2B0202
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, NMDA 3A0101
Muscarinic acetylcholine receptor M50012
Muscarinic acetylcholine receptor M30012
Muscarinic acetylcholine receptor M20012
GALC protein2002
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
cytochrome P450 2C9 precursor1001
Cytochrome P450 2A60112
Muscarinic acetylcholine receptor DM10101
Cytochrome P450 2A130112
CDGSH iron-sulfur domain-containing protein 10101
tyrosine-protein kinase Yes1001
Free fatty acid receptor 10011
Peroxisome proliferator-activated receptor gamma0101
Steryl-sulfatase0101
Tyrosine-protein phosphatase non-receptor type 10204
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Amine oxidase [flavin-containing] B0101
Amine oxidase [flavin-containing] A 0101
Peroxisome proliferator-activated receptor alpha0101
Carnitine O-palmitoyltransferase 2, mitochondrial0101
Peroxisome proliferator-activated receptor gamma0247
Peroxisome proliferator-activated receptor gamma0112
Carnitine O-palmitoyltransferase 1, liver isoform0101
Peroxisome proliferator-activated receptor alpha0112
Enoyl-[acyl-carrier-protein] reductase [NADH] 0101
CDGSH iron-sulfur domain-containing protein 20101
Hsf1 protein0012
PPM1D protein1001
karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b0011
luciferase0001
Estrogen receptor0202
Progesterone receptor0203
Glucocorticoid receptor0112
Glucocorticoid receptor0011
Mineralocorticoid receptor 0213
Androgen receptor0202
Glutamine synthetase0011
Androgen receptor0101
Nociceptin receptor0011
Estrogen receptor beta0202
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase0011
Chain H, Immunoglobulin Igg1 Heavy chain0011
Chain L, Immunoglobulin Igg1 Lambda Light Chain0011
Chain A, DODECIN0011
Chain A, DODECIN0011
Chain C, DODECIN0011
Chain E, DODECIN0011
NPYLR7B0011
Riboflavin-binding protein0112
Beta-1 adrenergic receptor0101
Glycine receptor subunit alpha-10011
Sodium-dependent dopamine transporter0101
Histamine H2 receptor0404
5-hydroxytryptamine receptor 7 0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 2A0101
D(2) dopamine receptor0101
5-hydroxytryptamine receptor 2B0101
Sodium channel protein type 5 subunit alpha0202
5-hydroxytryptamine receptor 1A0202
Multidrug and toxin extrusion protein 20101
Met repressor 0022
Protein arginine N-methyltransferase 50011
Histone H3K27 methylase0001
Phenylethanolamine N-methyltransferase0012
S-adenosylmethionine decarboxylase proenzyme0102
Protein-L-isoaspartate(D-aspartate) O-methyltransferase0101
Catechol O-methyltransferase0001
Protein arginine N-methyltransferase 10101
Methylosome protein 500011
Estrogen receptor beta0001
Inhibitor of nuclear factor kappa-B kinase subunit beta0001
5'-AMP-activated protein kinase subunit beta-20001
Albumin0123
Polymerase acidic protein0011
Stromelysin-10011
Tyrosine-protein phosphatase YopH0101
High mobility group protein B10011
Aldo-keto reductase family 1 member B10101
Prolyl 4-hydroxylase subunit alpha-10101
Estrogen receptor0001
Cystathionine gamma-lyase0101
5'-AMP-activated protein kinase subunit gamma-10001
5'-AMP-activated protein kinase catalytic subunit alpha-20001
Xanthine dehydrogenase/oxidase0101
5'-AMP-activated protein kinase catalytic subunit alpha-10001
Carbonic anhydrase0101
Solute carrier family 22 member 60101
Solute carrier family 22 member 70001
Solute carrier family 22 member 80101
Ubiquitin-like domain-containing CTD phosphatase 10101
5'-AMP-activated protein kinase subunit gamma-30001
5'-AMP-activated protein kinase subunit gamma-20001
5'-AMP-activated protein kinase subunit beta-10001
Pyruvate kinase PKM0011
Neutral amino acid transporter A0101
Neutral amino acid transporter B(0)0101
Amino acid transporter0101
Caspase-71001
caspase-31001
Carboxypeptidase M0101
5-hydroxytryptamine receptor 1B0213
5-hydroxytryptamine receptor 1E0101
5-hydroxytryptamine receptor 1F0213
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 1B0101
5-hydroxytryptamine receptor 1D0101
5-hydroxytryptamine receptor 1B0101
Cereblon isoform 40202
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4C0101
DNA-binding protein Ikaros0001
DNA damage-binding protein 10112
Protein cereblon0214
serine/threonine-protein kinase PLK12002
Cytochrome P450 2B10101
Chain X, Thyroid hormone receptor beta-10011
Chain X, Thyroid hormone receptor beta-10011
Solute carrier organic anion transporter family member 1A40001
Solute carrier organic anion transporter family member 1A50001
Rap guanine nucleotide exchange factor 31001
Transthyretin0102
Thyroid hormone receptor alpha0011
Thyroid hormone receptor beta0011
Proliferating cell nuclear antigen0101
Retinoic acid receptor RXR-alpha0022
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20001
Solute carrier organic anion transporter family member 1A30001
Solute carrier organic anion transporter family member 4C10101
Monocarboxylate transporter 80001
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10203
D-alanyl-D-alanine dipeptidase0101
Glycoprotein0101
Muscarinic acetylcholine receptor M20011
Catechol O-methyltransferase0101
Potassium voltage-gated channel subfamily A member 30101
Multidrug resistance-associated protein 1 0214
Chloroquine resistance transporter0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]